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Cambrian Ventures

Venture capitaloperating company · company profile

San Francisco · Pre-Seed–Seed · 2 people tracked

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1,874 people in our graph share verified history with the Cambrian Ventures team — schools, employers, funds. One of them is your warm intro.

Iva Messyunlockedknows Rex Salisbury · together at Andreessen Horowitz (overlapped)
knows the team · via Thatch
×7knows the team · via The London School of Economics and Political Science (LSE)
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Investment thesis

Cambrian invests in early-stage fintech startups, believing the next evolution of fintech will come from strong founders backed by strong networks. It writes $300k to $1mm+ checks at pre-seed and seed, acting as lead, co-lead, or participant. Beyond capital, the firm activates the Cambrian network of founders, investors, and operators to help portfolio companies with insights, funding, early hires, customers, channel partners, and infrastructure. Its interests span the breadth of fintech, including payments, banktech, supply chain, insurtech, accounting and tax, capital markets, healthtech-fintech, HR-fintech, consumer finance, lending, wealthtech, identity and fraud, regtech, blockchain and crypto, proptech, and retail/e-commerce.

Source: firm website, verified Aug 3, 2026.

Stage
Pre-Seed–Seed
Check
$300K – $1M
HQ
San Francisco, CA, US
Leads rounds
Leads
Instruments
Equity
Founded
2000
Tracked investments
12

Team · 2 people

from the firm's website & public directories
Alexander J. Roepers· Executive Officer

What they invest in

from 11 of 12 portfolio companies

Enterprise Software ×7Fintech ×7SaaS ×7AI & Machine Learning ×6Healthtech ×4Digital Health ×2InsurTech ×2Data & Infrastructure ×1

HQs:United States×6Canada×2

Investments · 12 tracked

founders shown can be your intro path

By year:2024 · 12023 · 12 dated

Uplinquplinq.coin𝕏✓ verified

Uplinq provides a global credit assessment and scoring platform for small business lenders, leveraging analytics from over $1.4 trillion in underwritten loans and 10,000+ data sources to approve loans that conventional underwriting would decline.

AI & Machine LearningFintechSaaSVancouver, CA

Ron Benegbi(Founder & CEO)inPatrick Reily(Co-Founder)in

BoardDerek Ellington(Former EVP, Head Small Business Banking, Wells Fargo)

Co-investorsATX Venture PartnersWedbush Ventures

32Health32health.careinNov 2024

LightSpun provides an AI-powered healthcare administration platform that automates claims processing, credentialing, benefit administration, and contact center operations for payors, providers, and dental service organizations.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechChestnut Hill, US

Shaju Puthussery(Executive Officer, Director)Deepak Ramaswamy(Executive Officer, Director)

BoardRohan Malhotra(Director)

PartnerRex Salisbury· solo GP

Co-investorsIndustry Ventures

Anatomyanatomy.comin

Anatomy automates financial workflows for healthcare organizations by consolidating claims, banking, and accounting data into a unified system.

AI & Machine LearningEnterprise SoftwareFintechHealthtech

Co-investorsMeridian Street CapitalOptum VenturesCanapi VenturesLightspeed Venture Partners

Asterastercare.comacquired by Elation

Aster provides patient management software and agentic AI voice tools for healthcare providers.

AI & Machine LearningDigital HealthHealthtech

Co-investorsCake VenturesCornerstone VCOctopus VenturesIVP (Institutional Venture Partners)Sequoia CapitalSterling Road+1 more

Everyevery.ioin𝕏

Every.io is a financial technology company that enables businesses to invest in U.S.

Enterprise SoftwareFintechFuture of WorkSaaSSan Francisco, US

Rajeev Behera(Founder)inBarry Peterson(Founder)in

Co-investorsRedpoint VenturesY CombinatorFormus CapitalOlive Tree CapitalWayfinder VenturesCamber Creek+3 more

Hellopaidhellopaid.comin𝕏

Paid is a financial technology platform that offers payroll and banking services, including high-yield checking accounts, early pay access, and rewards programs for employees and business owners.

FintechHR TechSaaS

Keeptrykeep.comin𝕏

Keep provides an all-in-one financial platform for Canadian businesses, offering business cards with higher credit limits, expense automation, global banking services, and growth capital financing.

Enterprise SoftwareFintechSaaSCanada, CA

Oliver Takach(Founder)in

Co-investors305 VenturesAngel Collective Opportunity FundBase Venture Management, Inc.Brainstorm VenturesData TechEvolution Ventures+1 more

Lightspunlightspun.comin

LightSpun provides a platform that consolidates core insurance operations, including claims processing, provider network management, and policy administration, for insurance companies and health plans.

AI & Machine LearningEnterprise SoftwareHealthtechInsurTech

Co-investorsBrewer Lane VenturesVirtue Ventures

OatFioatfi.comin𝕏

OatFi operates a B2B credit network that embeds working capital into B2B payments, providing credit at the point of invoicing and payment.

Data & InfrastructureEnterprise SoftwareFintechSaaSNew York, US

John Jordan(Co-Founder & CTO)inMike Barbosa(Co-Founder & CEO)in

Co-investorsDunbar CapitalEvolution VenturesLorimer VenturesPICUS CAPITALQED InvestorsWhite Star Capital

Oysterwithoyster.comin𝕏

Oyster builds AI software for the insurance industry that connects customers, agencies, and carriers through an operating system featuring integrated digital workers that autonomously handle tasks across the insurance value chain.

AI & Machine LearningInsurTechSaaS

Co-investorsConversion CapitalHypothesisInterlace VenturesPosition Ventures

Salsasalsa.devin

Salsa builds modern payroll infrastructure for financial software platforms and businesses.

Enterprise SoftwareFintechSaaSSan Francisco, US

John Kramer(Founder)inJuan Barroso(Founder)in

Co-investorsBetter Tomorrow VenturesEvolution VenturesGreycroftSemperVirens Venture CapitalAltos VenturesDefinition

Vigil SoftwareJul 2023

Pataskala, US

Reis Renneker(Chief Technology Officer)inJonathan Mason Entingh(Chief Executive Officer)

Co-investorsM25

Exits · 1

IPOs and acquisitions across the tracked portfolio

Asteracq. by Elation

Portfolio news

latest coverage across their companies

Frequently asked questions

What stage does Cambrian Ventures invest at?
Cambrian Ventures invests at the Pre-Seed, Seed stages.
What is Cambrian Ventures's typical check size?
Cambrian Ventures typically writes checks of $300K – $1M.
What sectors does Cambrian Ventures focus on?
Cambrian Ventures focuses on Crypto & Web3, E-commerce, Fintech, Healthtech, HR Tech, InsurTech, PropTech, SaaS.
Where is Cambrian Ventures located?
Cambrian Ventures is headquartered in San Francisco, US.
Does Cambrian Ventures lead rounds?
Yes, Cambrian Ventures leads investment rounds.

Media · Podcasts & interviews

featuring the team

#411: Rex Salisbury of Cambrian Ventures

Peter Renton · Rex Salisbury

Building a Community-Driven VC with Rex Salisbury of Cambrian Ventures

Ripple Ventures · Rex Salisbury

Podcast 411: Rex Salisbury of Cambrian Ventures

Fintech Nexus · Rex Salisbury

America's #2 Neobank That Nobody Talks About

Rex Salisbury

⁠How AI Rewrote Ramp's Product Playbook

Rex Salisbury

Startup Ideas Are Boring Now (Ex-YC Partner Dalton Caldwell)

Rex Salisbury

Images

Cambrian Ventures photo

Co-investors · 34

Kleiner Perkins

Kleiner Perkins is a venture capital firm that backs founders across technology and life sciences, from early stage through growth.

Both backed · 1
$500K – $15M
PICUS CAPITAL

Picus Capital is a privately financed venture capital investor focused on early-stage technology ventures, having backed over 170 companies with a long-term, entrepreneur-aligned approach.

Both backed · 1
$100K – $300M
QED Investors

QED Investors is a venture capital firm focused on financial services, founded by former Capital One executives to back founders bringing transparency and fairness to fintech.

Both backed · 1
$30K – $25M
Conversion Capital

Conversion Capital is a venture firm that has invested in and supported founders since 2015, focusing on software, AI/ML, and cloud technology. It partners with companies early and runs a fellowship program called Conversion Labs.

Both backed · 1
$500K – $5M
M25

M25 is an early-stage venture firm based in Chicago that invests exclusively in tech startups headquartered in the U.S. Midwest. Since 2015 it has become the region's most active investor, using an analytical scorecard approach to screening startups.

Both backed · 1
$500K – $3M
Andreessen Horowitz

Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.

$500K – $50M
GV (Google Ventures)

GV (Google Ventures) is a venture capital firm that has invested in artificial intelligence and machine learning since its early days, building a global portfolio of more than 100 AI companies across infrastructure, life sciences, and applications.

$250K – $50M
Insight Partners

Insight Partners is an investment firm focused on accelerating revenue and profit growth in software companies, providing capital and operational support through its Insight Onsite team.

$120M – $350M
BoxGroup

BoxGroup is an early-stage venture capital firm that invests in startups at their earliest stages.

$1M
Susa Ventures

Susa Ventures operates two early-stage technology funds that invest in companies leveraging data, network effects, and economies of scale.

$1M – $5M
Liquid Ventures

Liquid 2 is an early- and growth-stage venture capital firm that invests in founders across all sectors of technology, providing capital along with support from a network of operators.

$250K – $5M
Innovation Endeavors

Innovation Endeavors is an early-stage venture fund that invests in founders and supports venture creation through pre-team and pre-idea programs. The firm provides portfolio companies with access to mentors, advisors, and an entrepreneur ecosystem.

$1M – $15M
22 more co-investors

Lookout VenturesTrajectory VenturesParadigmBase10 PartnersWEEKENDBanana CapitalCowboy VenturesFootworkNextGen Venture PartnersNotion CapitalKearny JacksonMischiefEnsemble VCVera EquityTTV CapitalJump CapitalTimespan VenturesFin CapitalMPG FundFlyover CapitalUpWestHoneyBook

Firms observed investing alongside Cambrian Ventures, from public investor directories. Shared companies are the overlap with Cambrian Ventures's recorded portfolio.

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