General Advance
Seed–Late Stage
Find your way into General Advance
What they invest in
from 43 of 44 portfolio companiesEnterprise Software ×30AI & Machine Learning ×27SaaS ×16Biotech ×9Deep Tech ×8Data & Infrastructure ×7Developer Tools ×7Fintech ×7
HQs:United States×31United Kingdom×4Germany×2Canada×1Israel×1Mexico×1
Investments · 44 tracked
founders shown can be your intro pathBy year:2026 · 12023 · 12022 · 32021 · 16 dated
FireTail is an AI security platform that discovers, assesses, and protects AI usage across an organization's employees, browsers, devices, applications, and agents.
AI & Machine LearningCybersecurityEnterprise SoftwareSaaSMclean, US
Jeremy Snyder(Executive Officer, Director)inRiley P.(Founder)inRiley Priddle(Executive Officer)
BoardMourad Yesayan(Director)in
Co-investorsPaladin Capital GroupSecure Octane
83 Sciences converts unpublished experimental research data into academic papers, patents, and commercialization opportunities for research organizations.
Advanced ManufacturingAI & Machine LearningBiotechDeep TechSan Francisco, US
Ian Naccarella(Founder)inEric Riesel(Founder)inYankang Yang(Founder)in
Co-investorsY CombinatorFounders FactoryGaingelsVentoWefunder
Alt-X operates an AI-powered infrastructure platform that connects buyers and sellers of private company stakes, starting with venture secondaries and expanding to other private assets.
FintechLos Angeles, US
Ryan Samadi(Founder)inMichael Wachsman(Founder)in
Co-investorsY Combinator
Applied Electrodynamics is building WaveSight, a hardware sensing product designed to see through walls and detect objects otherwise not visible.
Advanced ManufacturingDeep TechHardwareSan Francisco, US
Bilgehan Avser(Co-founder & CEO)inBrian Huppi(Founder)inPaul Leutheuser(Founder)inGeorge McLean(Founder)in
Co-investorsTranspose Platform ManagementY CombinatorKleiner PerkinsLiquid VenturesMassive Tech VenturesOurCrowd+5 more
AtlasDiscovery develops foundation models of patient drug response trained on pre-clinical and clinical data to improve drug trial design and success rates.
AI & Machine LearningBiotechHealthtechSan Francisco, US
Sanjukta Bhattacharya(Founder)inShaamil Karim(Founder)in
Co-investorsY CombinatorAlumni VenturesFrialeGlasswing VenturesLightspeed Venture PartnersOak HC/FT+2 more
Cardinal Gray automates vehicle titling and DMV documentation workflows for lenders and financial institutions.
AI & Machine LearningEnterprise SoftwareFintechNew York City, US
Jack Chapman(Founder)inMuhammad Khattak(Founder)inGrant Pease(Founder)in
Co-investorsY CombinatorAlloy FundAndreessen HorowitzKrew Capital VenturePeterson Venture PartnersTwenty Two Ventures+1 more
ClearMix operates a platform that pairs professional video producers with clients to create marketing and sales videos remotely, achieving faster turnaround and lower costs than traditional production methods.
Enterprise SoftwareMarketing TechNew York City, US
Gabe Ruttner(Founder)inTomer Dorfan(Founder)in
Co-investorsChaos VenturesNOEMIS VenturesSprint VcY CombinatorBloomberg BetaLiquid Ventures+6 more
Conntour provides a platform that allows security teams to search, monitor, and query video footage from thousands of cameras using natural language commands, enabling features like historical footage search, real-time alerts, and data extraction without requiring pre-configured detection rules.
Advanced ManufacturingTel Aviv-Yafo, IL
Matan Goldner(Co-Founder & CEO)inTomer Kulla(Co-Founder & CTO)in
Co-investorsOlive Tree CapitalY Combinator468 CapitalAnD VenturesExceptional CapitalGeneral Catalyst+6 more
Cosmonic offers Cosmonic Control, a Kubernetes-native WebAssembly control plane that runs Wasm components alongside containers using existing namespaces, RBAC, CI/CD, and observability tooling.
Cloud ComputingDeveloper ToolsEnterprise SoftwareArlington, US
Kevin Hoffman(Founder)in
Co-investorsVertex VenturesWolfpack Investor NetworkRelentless VCRembrandt Venture Partners
DryMerge provides AI agents that automatically capture customer interaction data from email, calendar, calls, and messaging tools, updating CRM systems like Salesforce and HubSpot without manual data entry.
AI & Machine LearningEnterprise SoftwareSales TechSan Francisco, US
Samuel Brashears(Founder)inEdward Frazer(Founder)in
Co-investorsRitual CapitalY CombinatorBreakpoint CapitalCapitalize VCGaingelsGarage Capital+2 more
EngageBio develops DNA-based medicines using proprietary non-viral delivery technology to achieve extended therapeutic expression from a single dose with low manufacturing complexity.
BiotechDigital HealthHealthtechSan Francisco, US
Will Olsen(Founder)in
Co-investorsCALIFORNIA INNOVATIONMetaplanetSciFoundersWorldQuant VenturesY Combinator10X Capital+8 more
Expanse predicts the GPU, memory, runtime, and failure risk of compute jobs before they run, so clusters do more work on the same hardware and reduce failed or overprovisioned jobs.
AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareSan Francisco, US
Ismaeel Bashir(Founder)inNikodem Bieniek(Founder)inYafet Melake(Founder)inEren Mendi(Founder)in
Co-investorsNew Enterprise Associates (NEA)Scribble VenturesY CombinatorAIP SeedCrane Venture PartnersCRV (Charles River Ventures)+10 more
Expanse provides attack surface management software that continuously discovers and monitors connected systems and exposed services to identify unknown security risks across hybrid and cloud infrastructure.
Cloud ComputingCybersecurityEnterprise SoftwareSaaS
Co-investorsWebb Investment NetworkAIP SeedCrane Venture PartnersRitual CapitalScribble VenturesStandard Capital+2 more
FinalDose develops a programmable DNA-targeting molecule designed to recognize and destroy cells carrying specific genetic sequences, with initial applications in oncology across cancer types.
AI & Machine LearningBiotechHealthtechLondon, GB
Li-Yao Huang(Founder)inSteven Lin(CTO & Co-Founder)inJeff Liu(CEO & Co-Founder)inLiyao Huang(CSO & Co-Founder)in
Co-investorsLobster CapitalScribble VenturesTranspose Platform ManagementY CombinatorZAKA VC468 Capital+13 more
Firecrawl provides an API to search, scrape, and interact with web content at scale, converting live internet data into clean markdown and structured data optimized for large language models, agents, and AI-native applications.
AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSan Francisco, US
Caleb Peffer(Co-Founder & CEO)inEric Ciarla(Co-Founder & Chief Growth Officer)inNicolas Silberstein Camara(Co-Founder & CTO)in
Co-investorsJude GomilaY CombinatorCrush VenturesMasad CapitalNexus Venture PartnersRedwood Trust
FullSeam provides AI agents that autonomously manage accounts receivable, accounts payable, cash application, and reconciliation tasks for finance teams.
AI & Machine LearningEnterprise SoftwareFintech
Thomas Dowling(Co-founder)inAaron Coppa(Co-founder)inGeoff Segal(Co-Founder)in
Co-investorsTranspose Platform ManagementY CombinatorAgrolimen VenturesClocktower VenturesDaft CapitalOurCrowd+6 more
Gaiia is a platform with developer-focused documentation and APIs designed to help developers build integrations.
Data & InfrastructureDeveloper ToolsEnterprise SoftwareSaaSRemote, US
Marc-André Campagna(Founder)inFrancis Careau(Founder)in
Co-investorsInovia CapitalJMI EquityY CombinatorAcequia Capital (AceCap)GTMfundInvestissement Quebec+2 more
Hardware Intelligence builds an agent-native toolchain for chip design, starting with Wave, an agentic waveform debugger for terminal use.
AI & Machine LearningDeep TechDeveloper ToolsEnterprise SoftwareHardwareSan Francisco, US
Athreya Anand(Founder)inRishov Sarkar(Founder)in
Co-investorsY CombinatorVela PartnersAera VCAmino CapitalFirst Degree CapitalFlex Capital Partners+4 more
Hyper provides a centralized knowledge system that connects to a company's internal information, automatically builds and maintains a knowledge graph, and enhances the performance of AI agents deployed within the organization.
Enterprise SoftwareFuture of WorkSan Francisco, US
Shalin Shah(Founder)inKanyes Thaker(Founder)in
Co-investorsY Combinator
A company developing computing solutions to solve NP-complete problems, focusing on reducing computational intractability for practical applications across domains.
AI & Machine LearningDeep TechDeveloper ToolsEnterprise SoftwareHardwareSan Diego, US
Co-investorsY CombinatorSouth Quad1984 Ventures Management, Llc640 OxfordFAST — by GETTYLABFour Cities+2 more
Keystroke is a platform for building specialized agents and workflow automations that integrate with coding agents like Claude Code and Cursor, allowing users to build actual TypeScript code that lives in their repository and deploy to the Keystroke platform for credential management, logging, and access control.
AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSaaSSalt Lake City, US
Blake Rouse(Founder)inDallin Bentley(Founder)in
Co-investorsY CombinatorBreakpoint CapitalContour Venture PartnersGaingelsGeneral CatalystKickstart+6 more
askLio is an AI-powered procurement platform that allows employees to request goods and services using natural language, automating the sourcing, negotiation, and execution of purchases.
AI & Machine LearningEnterprise SoftwareSaaSBY, DE
Vlad Keil(Founder)inLukas Heinzmann(Founder)inTill Wagner(Founder)inVladimir Keil(CEO)in
Co-investorsY CombinatorAndreessen HorowitzHeliad AGLightspeed Venture PartnersSAV (Scale Asia Ventures)Titan Capital+6 more
WithAI provides an AI platform called Multiplier that helps asset managers and investment firms automate research and decision-making by leveraging frontier AI agents that operate securely on clients' own cloud infrastructure.
AI & Machine LearningEnterprise SoftwareFintechSan Francisco, US
Ian McInnis(Founder)inBenjamin Finch(Founder)inBen Finch(Co-founder, CTO, President)inDavid Snider(Executive Officer, Director, Promoter)
BoardGregory Gretsch(Director)William Galvin(Director)
Co-investorsGoAhead VenturesY CombinatorAmino CapitalCRV (Charles River Ventures)Lux CapitalMultifaceted Capital+4 more
Overstand is a data platform that aggregates customer insights from across an organization's dispersed data sources and systems to help leadership teams validate product decisions and align on direction.
AI & Machine LearningData & InfrastructureEnterprise SoftwareSaaSNew York City, US
Mihir Patil(Founder)inDerrick Cheng(Founder)in
Co-investorsTranspose Platform ManagementY Combinator468 CapitalAgrolimen VenturesForward Deployed VCRebel Fund+1 more
ParcelBio develops APEXm, a proprietary mRNA platform that enhances protein expression for longer-lasting therapeutic effect compared to conventional mRNA technologies.
AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US
David Weinberg(Founder)inChris Carlson(Founder)in
BoardMorgan Cheatham(Director)in
Co-investorsY CombinatorBreyer CapitalGeneral CatalystLexi VenturesMetaplanetNorth South Ventures+9 more
Parsewise builds enterprise software that transforms fragmented, unstructured data into structured evidence to enable organizations to make reliable risk decisions.
AI & Machine LearningData & InfrastructureEnterprise SoftwareFintechInsurTechSaaSLondon, GB
Max Hofer(Founder)inGreg Csegzi(Founder)inGergely Csegzi(Founder)in
Co-investorsOxonian VenturesY CombinatorNetwork VC
Pharosyn uses AI to continuously monitor clinical trials, regulatory filings, press releases, and earnings calls, and produce strategic competitive intelligence reports on a company's competitors.
AI & Machine LearningBiotechEnterprise SoftwareSaaSLondon, GB
Stephen Cowley(CEO)inJoshua Hampson(CTO)in
Co-investorsEntrepreneur FirstMoonfire VenturesTranspose Platform Management
Phosphorus provides a cybersecurity remediation platform for Internet of Things (xIoT) devices in enterprise environments, offering visibility, patching, and compliance capabilities that integrate with existing security tools.
CybersecurityEnterprise SoftwareIoTNashville, US
Chris Rouland(Founder)inEarle Ady(Executive Officer, Director)Charles Andros(Director)Martin LeRoy(Executive Officer)
BoardJR Smith(Director)Arthur Coviello, Jr.(Director)
Co-investorsEvolution Equity PartnersFirstMark CapitalMassMutual VenturesNeva Sgr.Service Provider CapitalSyn Ventures Seed Management Llc+2 more
Plerk provides virtual benefit cards that let companies allocate budgets for employee perks, allowing workers to choose from merchant options while maintaining centralized billing and spending controls across distributed teams.
Enterprise SoftwareFintechMarketplacesSaaSGuadalajara, MX
Miguel Medina(Founder)inAngel Arias(Founder)inAntonio Martinez Quintero(Founder)inJosé Antonio Martínez QuinteroAntonio Martinez(Director, Promoter)in
Co-investors500 GlobalFirst Check VenturesHorseplay VenturesMGV CapitalStartupsY Combinator+3 more
Polymorph operates a continuous experimentation platform that enables product teams to run thousands of experiments simultaneously across consumer applications.
Enterprise SoftwareMarketing TechSaaSSan Francisco, US
Co-investorsY CombinatorAmino CapitalAndreessen HorowitzFounders FactoryWefunder
Radiant Security offers an AI-powered Security Operations Center (SOC) platform that uses AI triage and research agents to investigate every security alert across attack surfaces such as endpoint, identity, network, cloud, and SIEM, escalating only significant cases with explainable reasoning.
AI & Machine LearningCybersecuritySaaS
Shahar Ben-Hador(Founder)inBarry Shteiman(Founder)in
Co-investorsAcrew CapitalCheyenne VenturesJibe VenturesLightspeed Venture PartnersNext47Uncorrelated Ventures
Rasyn.ai offers Marigold, an AI research assistant that lets scientists ask research questions, run tools, or delegate entire tasks, returning results such as structures, charts, code, and papers in panels.
AI & Machine LearningBiotechDeep TechHealthtechSaaSSan Francisco, US
Ayush Chauhan(Founder)inDaood Hashmi(Founder)inAnsh Tiwari(Founder/CEO)
Co-investorsY CombinatorArray Ventures Management LlcCaladanCapitalize VCCharacterInflection Point Ventures+4 more
SchedulingWiz builds automated physician scheduling software for hospital departments and medical institutions.
Enterprise SoftwareHealthtechSaaSWashington, US
Samuel Oberly(Founder)inZachary Dermody(Founder)inAbdelrahman Hamimi(Founder)in
Co-investorsY CombinatorTeamworthy Ventures
Shotwell.ai provides automated failure detection from video data for robotics companies, analyzing footage from both development and production environments to generate annotations with minimal latency.
Advanced ManufacturingRoboticsSan Francisco, US
Farhan Khan(CEO, Founder)inAli Abdalla(Founder)inAli Abid(Founder)inNour Eldifrawy(Founder)in
Co-investorsY CombinatorAmino CapitalRace CapitalRobinhood
Solve Intelligence provides AI-powered software for patent drafting, prosecution, and claim analysis for legal professionals and corporate IP departments.
AI & Machine LearningEnterprise SoftwareLegalTechLondon, GB
Chris Parsonson(Founder/CEO)inSanj Ahilan(Founder)inAngus Parsonson(Founder)in
Co-investorsAmino CapitalCoho DeeptechFoundersX VenturesM12 (Microsoft's Venture Fund)Operator CollectiveSAV (Scale Asia Ventures)+15 more
Standard Machines is building reinforcement learning environments for long-horizon chip design tasks.
AI & Machine LearningDeep TechEnterprise SoftwareSemiconductorsSan Francisco, US
Jacob Peake(Founder)in
Co-investorsTranspose Platform ManagementVela PartnersY CombinatorAndreessen HorowitzRobinhood
Synchron develops brain-computer interface technology delivered via catheter to restore or improve motor and cognitive function in people with impairment or decline.
BiotechDeep TechMedical DevicesCampbell, US
Thomas James Oxley(Executive Officer, Director)Nicholas Opie(Director)inThomas Oxley(Founder)in
BoardRahul Sharma(Director)Alex Morgan(Director)inMartin Dieck(Director)
Co-investorsARCH Venture PartnersForepont Capital PartnersID8 InvestmentsKaleida CapitalKhosla VenturesAlumni Ventures+11 more
Talking Computers uses AI-driven agents to optimize machine learning training and inference infrastructure, working across multi-week engagements to run parallel experiments and improve performance on customer workloads, including GPU kernel acceleration and model latency.
AI & Machine LearningEnterprise SoftwareToronto, CA
Zayaan Mulla(Founder)inParsa Bahraminejad(Founder)in
Co-investorsY CombinatorNorthside VenturesPioneerRobinhood
Toven provides AI agents that automate compliance work for institutional brokerages, performing a first-pass review of communications, surveillance alerts, and research reports and auto-clearing false positives while escalating cases that need human judgment.
AI & Machine LearningEnterprise SoftwareFintechNew York City, US
Batu Balci(Co-Founder & CEO)inSam Turchetta(Founder)in
Co-investorsY CombinatorKyber Knight CapitalMatrixVento
Unpopular Ventures (UV) is an early-stage venture capital firm that invests in startups across sectors globally.
Sector Agnostic
Peter Livingston(Founder)in
Co-investorsPeakAfore CapitalAmino CapitalCIVGoAhead VenturesLux Capital+4 more
Velorium develops transformational medicines by combining scientific research with patient-focused collaboration.
BiotechHealthtechMedical DevicesSan Francisco, US
Pouya Modareszadeh(Founder)inParsa Modareszadeh(Founder)in
Co-investorsMetaplanetMyAsiaVCSciFoundersTranspose Platform ManagementY Combinator468 Capital+5 more
Ventura automates quote generation and order processing for sales teams by extracting information from emails, images, and call transcripts, then pushing structured data directly to ERPs and CRMs.
Advanced ManufacturingAI & Machine LearningEnterprise SoftwareSaaSSan Francisco, US
Swen Koller(Founder)inJack Collins(Founder)in
Co-investorsY CombinatorRebel FundUnpopular Ventures
Windsor produces software that generates individualized video messages by using AI to synthesize variations of a single recorded video with unique recipient details, enabling mass personalization at scale.
AI & Machine LearningEnterprise SoftwareSaaSSan Francisco, US
Pranay Prakash(Founder/CEO)inAndrew Faust(Founder)in
Co-investors7percent VenturesY CombinatorAfore CapitalFour CitiesKearny JacksonLeyden Ventures+6 more
Zeit AI builds an autonomous AI system that connects enterprise data sources, prepares data, and converts business questions into operational applications for operators and managers in European companies.
AI & Machine LearningData & InfrastructureEnterprise SoftwareSaaSMunich, DE
Leopold von Waldthausen(Founder)inMarvin Christopher Bornstein(Founder)in
Co-investorsY CombinatorTranspose Platform ManagementACE & CompanyAcequia Capital (AceCap)CervinOxford Seed Fund+1 more
Portfolio news
latest coverage across their companiesFirecrawl · siliconangle.com · Sep 22, 2026
Zeit AI · eu-startups.com · Sep 3, 2026
TovenAI · ycombinator.com · Aug 19, 2026
Rasyn · ycombinator.com · Aug 3, 2026
Applied Electrodynamics, Inc. · ycombinator.com · Jul 30, 2026
Keystroke · ycombinator.com · Jul 10, 2026
Parsewise · ycombinator.com · May 26, 2026
Engage Bio · biospace.com · May 20, 2026
Frequently asked questions
- How many investments has General Advance made?
- General Advance has 44 tracked investments, 4 of which have exited, including 1 dated in the last 24 months.
- What stage does General Advance invest at?
- General Advance invests at the Seed, Late Stage stages.
Similar investors
83North is a global venture capital firm that invests in and helps entrepreneurs build large, category-defining companies, backing startups across multiple stages and sectors.
8VC is a venture capital firm investing across logistics, life sciences, healthcare, IT infrastructure, and government/defense, guided by its Smart Enterprise thesis focused on data integration and platform network effects.
Accel is a venture capital firm that partners with exceptional teams, positioning itself as a first partner to founders globally.
AirTree Ventures runs Pathfinders, a free four-week in-person program in Sydney for young builders (high-school graduates up to age 23) to work on a real product, access the AirTree team and founders, and build a peer network.











__Twitter.png)






































.png)

















































-2.png)

































































































































