Acephale Ventures
Seed · 1 people tracked
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Investment thesis
Acephale Ventures is a Chicago-based principal investment firm that deploys capital in both early-stage venture and public markets. It invests internationally.
Team · 1 people
from public directoriesWhat they invest in
from 7 of 7 portfolio companiesAdvanced Manufacturing ×5AI & Machine Learning ×5Hardware ×4Robotics ×3Deep Tech ×2Enterprise Software ×2Fintech ×2Circular Economy ×1
HQs:United States×5United Kingdom×2
Investments · 7 tracked
founders shown can be your intro pathDenta embeds AI engineers into dental organizations to automate business operations and administrative processes using AI.
AI & Machine LearningEnterprise SoftwareFintechHealthtechInsurTechSan Francisco, US
Jack Beecher(Founder)in
Co-investorsY CombinatorAV CapitalDTA Capital Advisors, LLCGood CapitalMetsu CapitalTwenty Two Ventures
Ethos Space develops technology to build and operate spaceports and infrastructure on the Moon using in-situ lunar resources, including construction material (Durandal), onsite propellant production (Prometheus), and materials for space-based data centers.
Advanced ManufacturingDeep TechHardwareSpace TechLos Angeles, US
Ross Centers(Founder/CEO)inBrogan BamBrogan(Founder/CTO)in
Co-investorsAcequia Capital (AceCap)AIR CapitalAtas VCCosmic Venture PartnersStreamlined VenturesTranspose Platform Management+12 more
Frontier Computing grows lab-cultured biological neural networks at large scale to serve as a training substrate for machine learning, colocating memory and compute to support training of large-parameter models.
Advanced ManufacturingAI & Machine LearningHardwareLondon, GB
Michael Domarkas(Founder/CEO)in
Co-investorsLocalGlobePioneerY CombinatorAmino CollectiveAndreessen HorowitzAtomico+15 more
Mass Magnetics manufactures high-performance neodymium-iron-boron rare-earth magnets in the United States from recycled and domestic feedstocks, using a rapid sintering process and machine learning to sort scrap by grade and chemistry.
Advanced ManufacturingCircular EconomyNew MaterialsRoboticsBoston, US
Matthew Groll(Founder)inEric Silver(Founder)in
Co-investorsY CombinatorAndreessen HorowitzDoomers Media LLCFounders FactoryInvestorXLiquid Ventures+9 more
Pacific builds modular, containerized supercomputers ("pods") that deploy onto stalled construction sites with existing grid connections to provide AI compute infrastructure.
Advanced ManufacturingAI & Machine LearningCleantechFintechHardwareRoboticsLondon, GB
Harper Dammann Smith(Founder)in
Co-investorsY CombinatorGaingelsRebel FundWSS
Robocurve develops open-source tools and benchmarks for evaluating the real-world capabilities of AI systems and robots.
Advanced ManufacturingAI & Machine LearningDeep TechHardwareRoboticsSan Francisco, US
Jay Chooi(Founder)inAris Zhu(Founder)in
Co-investorsPioneerY CombinatorCapitalize VCDecasonicDoomers Media LLCGaingels+10 more
Studio builds simulated "societies" that model consumer cohorts of a market and runs a company's proposed decisions—such as price changes, product placements, or promotions—through them to forecast outcomes before launch.
AI & Machine LearningData & InfrastructureEnterprise SoftwareMarketing TechSan Francisco, US
Cameron Malloy(Founder)inNikita Mullangi(Founder)in
Co-investorsPioneerVela PartnersY CombinatorImpact46Merak Capital
Portfolio news
latest coverage across their companies
Robocurve · svpost.com · Sep 14, 2026
Frontier Computing · ycombinator.com · Aug 31, 2026
Ethos Space Resources · ycombinator.com · Aug 25, 2026
Mass Magnetics · ycombinator.com · Aug 18, 2026
Frequently asked questions
- How many investments has Acephale Ventures made?
- Acephale Ventures has 7 tracked investments.
- What stage does Acephale Ventures invest at?
- Acephale Ventures invests at the Seed stage.
- What sectors does Acephale Ventures focus on?
- Acephale Ventures focuses on Advanced Manufacturing, Enterprise Software, Fintech.




















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