ZAKA VC
Venture capitalSan Francisco · Pre-Seed–Series A · 1 people tracked
Investment thesis
ZAKA VC is a seed and pre-seed venture fund that backs founders with global ambition regardless of location, aiming to build a bridge between North America and Europe. It invests mainly in the US and Europe, with a particular focus on the Health & Biotech and Industrial Tech verticals. The firm positions itself as founders backed by entrepreneurs, and has invested in 95 companies across five continents.
Source: firm website, verified Aug 3, 2026.
Team · 1 people
from public directories
What they invest in
from 68 of 88 portfolio companiesAI & Machine Learning ×28Biotech ×21Healthtech ×19Deep Tech ×15SaaS ×12Enterprise Software ×11Advanced Manufacturing ×7Data & Infrastructure ×7
HQs:United States×25United Kingdom×7Germany×4Estonia×3Austria×2Czechia×2
Investments · 88 tracked
founders shown can be your intro pathBy year:2026 · 22025 · 12024 · 22023 · 12022 · 12021 · 18 dated
Alixia develops therapeutics targeting tumor ecosystems to address cancer drug resistance and age-related diseases.
BiotechDeep TechHealthtechMedical DevicesSan Francisco, US
Olof Mollstedt(Founder)inHelen Chen(Founder)in
BoardSungwon Lim(Director)
Co-investorsY Combinator
Webel is an online marketplace that connects consumers with local professionals offering home services such as cleaning, private tutoring, beauty, and physiotherapy.
ConsumerFuture of WorkMarketplaces
Co-investorsTrind Ventures
Ateios develops electrode manufacturing techniques designed to accelerate production speed, reduce carbon emissions, and decrease the physical footprint of battery manufacturing and gigafactories.
Advanced ManufacturingCleantechEnergyMedical DevicesNew MaterialsLa Jolla, US
Terry Taber(CTO)
Co-investorsCarat Venture PartnersCharmides CapitalElevate VenturesGood Growth CapitalHG VenturesTechstars+2 more
Avelis audits medical claims using AI and clinician review to identify billing, coding, and contract errors for health plans and third-party administrators.
AI & Machine LearningHealthtechInsurTech
Angel Onuoha(Founder)inAhmad Shehu(Founder)in
Co-investorsY CombinatorGFT Ventures
b12 develops AI agents and lab automation software to help chemists plan, optimize, and execute the synthesis of complex molecules.
AI & Machine LearningBiotechDeep TechEnterprise SoftwareHealthtechRoboticsSan Francisco, US
Zlatko Jončev(Founder)inAndres Bran(Founder)in
Co-investorsY CombinatorTranspose Platform Management
bit.bio is a synthetic biology company that engineers human induced pluripotent stem cells into defined cell types for research, drug discovery, and cell therapy applications.
BiotechDeep TechHealthtechMedical Devices
Dr Mark Kotter(Founder)Przemek Obloj(CEO)
Co-investorsForesite CapitalBlueYard CapitalARCH Venture PartnersDynamk CapitalGood AI CapitalMetaplanet+1 more
Mews is a cloud-based hospitality platform and property management system (PMS) for hotels, covering booking, pre-arrival, check-in, in-stay purchases, point of sale, and check-out.
Cloud ComputingPropTechSaaSTravel & HospitalityPrague, CZ
Richard Valtr(Founder)in
Co-investorsBattery VenturesColumbia Lake PartnersNotion CapitalOutrun VenturesAtomico
Blockmate provides crypto infrastructure and compliance tools for banks and fintech companies, including portfolio management, payment integration, and AML compliance features accessible via a single API.
Crypto & Web3Enterprise SoftwareFintech
Co-investorsBADideas.fundDEPO VenturesDiaspora Ventures
Bluejay develops tools for improving the reliability of generative AI systems in production environments.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSan Francisco, US
Rohan Vasishth(Founder)inFaraz Siddiqi(Founder)in
Co-investorsFloodgateHomebrewY Combinator
Bullseye Biosciences discovers drug molecules directly in living cells using directed evolution to target difficult intracellular proteins and protein interactions implicated in cancer and other serious diseases.
AI & Machine LearningBiotechDeep Tech
Corey Gray(Co-founder and CEO)Michael McKeown(Co-founder and Head of Research)
Co-investorsIllumina Ventures
CellType uses AI agents and biological models to automate drug discovery, having identified a novel cancer treatment signal and partnering with major pharmaceutical companies.
BiotechHealthtechNew York City, US
David van Dijk(Co-Founder & CEO)inIvan Vrkic(Co-Founder)in
Co-investorsACVC PartnersY Combinator
Cirrus Therapeutics is a biotech developing gene and cell therapies based on ocular immunology to treat dry age-related macular degeneration (AMD), including an AAV gene therapy to restore the IRAK-M immune regulator and a next-generation retinal pigment epithelium (RPE) cell therapy for advanced geographic atrophy.
BiotechHealthtechLongevityCambridge, US
Ying Kai Chan(Co-founder & CEO)in
Conntac provides a self-service platform for customer support, enabling end users and service teams to resolve issues independently while helping companies reduce support costs and improve customer satisfaction.
Enterprise SoftwareSaaSGermany, DE
Co-investorsBasinghall PartnersBayern Kapital
Creasallis develops CreaTap, a patented "plug-and-play" antibody modification technology that improves the penetration of antibody-based drugs into solid tumours, applicable to monoclonal, bispecific, and antibody-drug conjugates.
Biotech
Zahra Jawad(Founder)
Co-investorsBlueYard CapitalPace VenturesKdT Ventures
CRUXO is a modular, self-service retail media platform that lets retailers, brands, and media agencies manage vendor marketing and ad campaigns across onsite, offsite, and in-store channels in one tool.
AdTechMarketing TechRetail Tech
Co-investorsPresto VenturesRockaway Ventures
DeepSeq develops AI-designed biologics, using datasets of billions to trillions of real protein interactions to predict properties such as binding affinity, specificity, immunogenicity, pharmacokinetics, and manufacturability.
AI & Machine LearningBiotechDeep Tech
Co-investorsIllumina Ventures
e-mobilio provides a digital ecosystem for electric mobility, offering fleet electrification, charging infrastructure, billing systems, and a digital purchase advisor with product matching for EV charging stations and wallboxes.
CleantechEnergyMobility & Transportation
Co-investorsSeed+SpeedÜbermorgen VenturesVireo Ventures
easySales is an all-in-one eCommerce management platform that automates order processing, product listing, and inventory across multiple marketplaces, online stores, invoicing software, and couriers.
E-commerceRetail TechSaaS
EdgeTrace provides AI-powered video search software that allows law enforcement and public safety agencies to query video footage in plain language, finding answers in seconds instead of hours of manual review.
AI & Machine LearningDefense TechEnterprise SoftwareGovTechSan Francisco, US
Kyle Orciuch(Co-Founder & CEO)in
Co-investorsY Combinator
ExcepGen develops biologics, gene therapies, and vaccines using synthetic biology approaches to create therapies that operate outside normal cellular regulation constraints.
AI & Machine LearningBiotechHealthtechSan Francisco, US
Thomas Folliard(Founder)in
Co-investorsOxonian VenturesPi CampusY Combinator
ExoMatter builds a software platform for materials research and development, providing tools to help scientists discover and evaluate materials faster.
AI & Machine LearningDeep TechNew MaterialsMunich, DE
Co-investorsTechFounders
FinalDose develops a programmable DNA-targeting molecule designed to recognize and destroy cells carrying specific genetic sequences, with initial applications in oncology across cancer types.
AI & Machine LearningBiotechHealthtechLondon, GB
Li-Yao Huang(Founder)inSteven Lin(Founder)inJeff Liu(Founder)in
Co-investorsLobster CapitalScribble VenturesY Combinator
Co-investorsDEPO Ventures
Co-investorsE2MC VenturesEmerald Development ManagersSeraphim SpaceTreeo VC
Human Archive is a data lab that collects, labels, and synchronizes multimodal sensor data (video, audio, tactile, motion capture) from 100,000+ contributors across homes, hospitality, agriculture, industrial, construction, and retail settings.
Advanced ManufacturingAI & Machine LearningData & InfrastructureDeep TechRoboticsSan Francisco, US
Raj Patel(Founder)inRushil Agarwal(Founder)inSamay Maini(Founder)inShloke Patel(Founder)in
Co-investorsY CombinatorNVP CapitalWing
BiotechCambridge, US
Myron Spector(Director)Pierre Colombe Dromel(Executive Officer, Director)Deepti Singh(Director)Michael Young(Director)
InGel Therapeutics develops engineered cell therapies for complex retinal degenerative diseases, combining retinal precursor cells with a biomimetic hyaluronic acid and gelatin hydrogel delivery matrix that mimics the human vitreous.
BiotechDeep TechHealthtech
Patrick Jiang(CEO & Co-founder)Pierre Colombe Dromel(Chief Technology Officer & Co-founder)Deepti Singh(Chief Scientific Officer & Co-founder)
Co-investorsMassVenturesThe Venture CollectiveService Provider Capital
Inversion Semiconductor develops next-generation semiconductor lithography equipment based on miniaturized particle accelerators that increase transistor density and improve chip manufacturing precision.
Advanced ManufacturingDeep TechHardwareRoboticsSemiconductorsSan Francisco, US
Rohan Karthik(Founder)inDaniel Vega(Founder)inRohan Shishir Karthik(CEO)inDaniel Ricardo Vega Bermudez(CTO)in
Co-investorsAnorak VenturesEntrepreneur FirstLobster CapitalMoonfire VenturesMyAsiaVCTranspose Platform Management+2 more
Kano Therapeutics develops circular single-stranded DNA (cssDNA) as a genetic payload for gene-editing and other DNA-based therapies, offering an alternative to viral vectors and double-stranded DNA.
BiotechDeep TechCambridge, US
Floris Engelhardt(Executive Officer, Director)John Vroom(Director)
BoardAnn DeWitt(Director)in
Co-investorsFifty YearsLaunchpad Venture GroupMetaplanetThe Engine VenturesVsquared Ventures
KiraGen Bio develops gene-edited, donor-derived cell therapies designed to resist tumor microenvironment suppression and maintain durable function.
BiotechDeep TechHealthtech
Co-investors2048 VenturesFifty Years
Lime Therapeutics is a biotechnology company developing lipid-altering medicines for cancer, cardiometabolic diseases, lysosomal storage diseases, and neurodegenerative disorders.
BiotechMedical DevicesNew York, US
Prakrit V. Jena(Co-founder & CTO)Shardule Shah(CEO)
Co-investorsHBS Angels of Boston
LunaBill provides AI automation software for hospital billing teams to manage denied claims and patient revenue cycles.
AI & Machine LearningEnterprise SoftwareHealthtechSaaSSan Francisco, US
Suhail Parry(Founder)inDavid Day(Founder)in
Co-investorsGarage CapitalLobster CapitalY Combinator
Mbodi develops AI-powered robots that can learn new tasks through natural language instructions and demonstration, eliminating the need for reprogramming when processes change.
Advanced ManufacturingAI & Machine LearningRoboticsNew York City, US
Xavier (Tianhao) Chi(Founder)inSebastian Peralta(Founder)in
Co-investorsACADEMY INVESTORAIN VenturesBetaworksFuel Venture CapitalImagination CapitalMozilla Ventures+5 more
MediSearch provides instant answers to medical questions sourced from reliable medical information.
AI & Machine LearningDigital HealthHealthtechWellness & FitnessLondon, GB
Eduard Oravkin(Founder)inMichal Pándy(Founder)in
Co-investorsAmino CapitalKAYAY Combinator
Miros builds a visual AI product for e-commerce retailers that reads shopper intent from behaviour to surface relevant products without requiring text search, aimed particularly at visual categories like fashion.
AI & Machine LearningE-commerceMarketing TechRetail TechTallinn, EE
Co-investorsTera VenturesBADideas.fundMetis VenturesSnatched VenturesSpecialist VC
Nephrogen develops AI-powered AAV delivery vehicles for genetic medicines targeting kidney and pancreatic diseases.
AI & Machine LearningBiotechData & InfrastructureHealthtechMedical DevicesNew York City, US
Demetri Maxim(Founder and CEO)Vivek Bhalla(Chief Medical Officer)
Co-investorsTechstarsY Combinator
Olio Labs develops drug combination therapies using machine learning to identify treatments that target multiple interacting proteins simultaneously, with initial candidates focused on obesity treatment.
BiotechHealthtech
David Tingley(Founder)inTom Roseberry(Founder)in
Co-investorsOverwater Ventures LlcSciFoundersScrum VenturesY Combinator
Orderlion provides an eCommerce and order-management platform for food & beverage wholesalers and distributors, offering a branded online ordering app, ERP integration, customer-specific pricing, sales analytics, and an AI inbox that converts email, WhatsApp, and voicemail orders into integrated orders.
E-commerceFoodTechSaaS
Co-investorsAxeleo CapitalBloomhaus VenturesRockstartSeed+SpeedSICTIC
ParcelBio develops APEXm, a proprietary mRNA platform that enhances protein expression for longer-lasting therapeutic effect compared to conventional mRNA technologies.
AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US
David Weinberg(Founder)inChris Carlson(Founder)in
BoardMorgan Cheatham(Director)in
Co-investorsY CombinatorBreyer CapitalGeneral CatalystLexi VenturesMetaplanetNorth South Ventures+3 more
Perfectbit generates high-quality, information-dense synthetic data for AI model training using formal proof systems, simulators, and executable tests rather than human annotation.
AI & Machine LearningData & InfrastructureEnterprise SoftwareSan Francisco, US
Seiji Yamamoto(Founder)inPeter Vajda(Founder)in
Co-investorsImagination CapitalY Combinator
Positive Carbon makes Scrappy-1, an autonomous AI-powered robot and analytics platform that monitors, identifies, weighs, and prices food waste in commercial kitchens.
AI & Machine LearningClimate TechFoodTech
Co-investorsBusiness Venture PartnersHeartfelt Capital
Promakhos Therapeutics develops immunomodulatory therapies to restore immune system balance and reduce chronic inflammation in diseases like Crohn's disease, ankylosing spondylitis, and psoriasis.
BiotechHealthtechBoston, US
Katerina Chatzi(Founder)inJasper Edgar Neggers(Founder)inAIKATERINI CHATZI(Executive Officer, Director, Promoter)
Co-investorsMetaplanetY Combinator
Readmio is a voice-reactive storytelling app that reads illustrated fairy tales and stories to children, adding sound effects and music that respond to the reader's voice for an interactive bedtime experience.
ConsumerEdTechMedia & Entertainment
Co-investorsSimpact VenturesDEPO VenturesZero Gravity Capital
Rendin is a rental platform in Estonia that connects landlords and tenants, offering digital lease agreements with insurance protection and background-checked tenants.
B2B MarketplacesInsurTechPropTechTallinn, EE
Co-investorsIron Wolf Capital
Salu is a healthcare provider offering online and in-person medical care, including doctor consultations, sick leave management, prescription renewals, and appointment scheduling, positioned as an alternative to a family doctor and to public or private health insurance.
Digital HealthHealthtechInsurTech
Co-investorsDEPO Ventures
Developing next-generation mRNA medicines by turning living cells into mRNA factories.
Sensible Biotechnologies develops a cell-based mRNA design and manufacturing platform that produces pure, low immunogenicity mRNA therapeutics for drug development.
AI & Machine LearningBiotechDeep TechHealthtechOxford, GB
Miroslav Gasparek(Founder)inMarian Kupculak(Founder)in
Co-investorsCivilization Ventures Management, LlcKAYARecode VenturesY CombinatorBlueYard Capital
SharpGrid provides a data platform for targeting and analyzing HoReCa (hotel, restaurant, café) outlets across 61 markets.
Data & InfrastructureMarketing Tech
Co-investorsCzech Founders VC
smino is a software platform for managing construction projects from planning to handover, enabling digital collaboration among all project participants on a single centralized system.
Construction TechEnterprise SoftwareSaaSSwitzerland, CH
Co-investorsBitStone CapitalSerpentine Ventures
Sorwe is a mobile app for digitalising HR processes, offering online employee training, engagement and performance measurement, and workplace atmosphere tracking.
Future of WorkHR TechSaaS
Co-investorsMetis VenturesTechOne Venture Capital
Superlinked builds SIE, an open-source inference engine that runs specialized AI models on shared GPUs, enabling organizations to reduce API costs and improve control over their AI infrastructure for search and document processing workloads.
AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsSan Francisco, US
DanielBen
Co-investorsIndex VenturesSamsung NextTheory VenturesEpisode1Firestreak VenturesKAYA+4 more
Supliful is a fulfillment and private-label platform that lets creators and entrepreneurs build consumer packaged goods (CPG) brands—such as supplements, coffee, and on-demand products—without holding inventory, handling manufacturing, or managing logistics.
B2B MarketplacesDirect to ConsumerE-commerceLogistics & Supply ChainWellness & FitnessDenver, US
Martins Lasmanis(CEO)in
Co-investorsBADideas.fundDiaspora VenturesNeer Venture Partners
Sutro provides production-grade backend infrastructure and APIs for applications through a declarative language called SLang, enabling developers to define data models and deploy complete backend systems with minimal effort.
Cloud ComputingData & InfrastructureDeveloper Tools
Co-investorsCrosscut VenturesLorimer Ventures
Sygaldry develops quantum-accelerated AI servers that combine multiple qubit modalities to speed up training and inference for AI models.
Advanced ManufacturingAI & Machine LearningHardwareQuantum ComputingAnn Arbor, US
Chad Rigetti(Founder)inIdalia Friedson(Founder)in
BoardChristian Garcia(Director)inAndrew Sather(Director)inMichael Keiser(Director)
Co-investorsEarth Venture CapitalExpeditionsGarage CapitalMVP VenturesPage One VenturesQubits Ventures+8 more
tripmakery operates an online booking platform and marketplace for organizing group trips across Europe, letting groups such as school classes, sports clubs, and companies search over 115,000 accommodations and receive real-time offers.
B2B MarketplacesMarketplacesSaaSTravel & HospitalityVienna, AT
Robert(Co-Founder)Ajmal(Co-Founder)
Co-investorsPUSH VenturesSpeedinvest
Velaris is an AI-native Customer Success Platform that centralizes customer data, tracks account health, predicts churn and expansion, and automates post-sales workflows such as QBRs, reporting, and follow-ups.
AI & Machine LearningEnterprise SoftwareSaaS
Co-investors42CAPOctopus Ventures
Verne Robotics develops robotics technology, with a focus on multi-modal perception capabilities.
Advanced ManufacturingAI & Machine LearningDeep TechRoboticsSan Francisco, US
Neil Nie(Founder)inAditya Jha(Founder)in
Co-investorsCrucible CapitalY Combinator468 Capital
VETSTOR develops technology for pet health management using data-driven approaches.
Digital HealthHealthtech
We Make Games is a blockchain game studio developing Gems & Goblins, a Play & Earn PvP game where players earn GNG tokens to spend on in-game purchases or trade on the Gemwelry marketplace.
Crypto & Web3GamingBratislava, SK
Wectory provides rent advance factoring and Direct Debit rent collection services for UK letting agents and property managers, allowing them to offer new revenue lines to landlords without holding funds or requiring regulatory licensing.
FintechPropTech
Co-investorsFlyer One Ventures
Co-investorsRed Bike Capital
Yenmo provides affordable lending products designed to promote healthy financial behavior and customer satisfaction.
FintechBengaluru, IN
Ashutosh Purohit(Founder)inAryan Agarwal(Founder)in
Co-investorsY Combinator
Zee Prime Capital is an investment firm focused on crypto and cypherpunk-oriented technologies, positioning itself as a long-term, flexible capital provider.
Crypto & Web3
Zephyr Fusion develops compact, in-orbit fusion power systems for space-based applications including microgravity manufacturing, data centers, defense, propulsion, and human habitation.
Advanced ManufacturingDeep TechEnergySpace TechSan Diego, US
Edward Hinson(Founder)inGalen Burke(Founder)in
Co-investorsSterling RoadY Combinator
Portfolio news
latest coverage across their companiesMbodi AI · automate.org · Jul 6, 2026
Bluejay · investing.com · Jun 2, 2026
Human Archive · finsmes.com · Jun 1, 2026
Sygaldry Technologies · thequantuminsider.com · May 16, 2026
PerfectBit, Inc. · ycombinator.com · May 14, 2026
FinalDose · ycombinator.com · May 12, 2026
CellType · startuphub.ai · May 12, 2026
ParcelBio · technews180.com · May 8, 2026
Frequently asked questions
- How many investments has ZAKA VC made?
- ZAKA VC has 88 tracked investments, including 3 dated in the last 24 months.
- What stage does ZAKA VC invest at?
- ZAKA VC invests at the Pre-Seed, Seed, Series A stages.
- What sectors does ZAKA VC focus on?
- ZAKA VC focuses on Advanced Manufacturing, AI & Machine Learning, Biotech, Climate Tech, Deep Tech, Enterprise Software, Fintech, Healthtech, Robotics, SaaS, Sector Agnostic.
- Where is ZAKA VC located?
- ZAKA VC is headquartered in San Francisco, US.
- Who does ZAKA VC co-invest with?
- ZAKA VC most often shares deals with Y Combinator, DEPO Ventures, Metaplanet, among 123 tracked co-investors.
Images
Co-investors · 8
Blueyard is a small equal partnership with offices in the US and Europe, investing in early-stage companies.
Trind Ventures is an early-stage venture capital firm that backs consumer and community-driven startups across Europe, supporting founders from the first investment through multiple rounds.
Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.
Alumni Ventures (AV) is a venture firm that gives accredited individual investors access to professionally managed, diversified venture portfolios by co-investing alongside leading lead VC firms. It offers annual funds, syndicate deal-by-deal investing, and various investor clubs.
Pioneer Fund is a venture capital firm investing in the top Y Combinator startups.
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Forum Ventures is a founder-first venture studio, accelerator, and pre-seed fund focused on early-stage B2B software startups, providing hands-on support from concept through first fundraising round.
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MizMaa Ventures is an early-stage, thesis-driven venture capital firm backing Israeli entrepreneurs building deep-technology solutions, offering hands-on support alongside long-term capital.
SeaX Ventures is a globally focused venture capital fund backing early-stage companies developing exponential and deep-tech technologies, with a strategic emphasis on bridging the U.S. and Southeast Asia.
Firms observed investing alongside ZAKA VC, from public investor directories. Shared companies are the overlap with ZAKA VC's recorded portfolio.
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