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BillionToOne

NASDAQ: BLLNYC S17

San Francisco, US · Founded 2016 · 300 employees · Public · Hiring · 30 known investors

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BillionToOne is a precision diagnostics company that uses molecular counting technology to develop non-invasive prenatal screening and liquid biopsy tests for early disease detection. The company focuses on making molecular diagnostics accurate, fast, and accessible to patients.

BiotechDigital HealthHealthtechMedical DevicesDiagnosticsGenomicsUnited States of AmericaAmerica / CanadaPartly Remote

Founders & leadership· Y Combinator alumni (S17)

BillionToOne was founded in 2016 by Oguzhan Atay, David Tsao, and Sukrit Silas.

OAOguzhan Atay
Oguzhan AtayFounderHe completed his PhD as a graduate fellow in Stanford University's Department of Biology, following earlier research work at the University of Oxford. He co-founded the company in 2017 and has led it since.
DTDavid Tsao
David TsaoFounderCo-founder & CTO of BillionToOne
SSSukrit Silas
Sukrit SilasCo-founder, Chief Science Officer2016–201830 Under 30 2019

Investors · 30

500 Globallisted by 500 GlobalPalo Alto · $150K

How we know: open dataset · 500 Global portfolio 2026-08 · Not right? Tell us

Asymmetry Ventureslisted by Asymmetry VenturesRichmond · $125K – $500Kvia Rob Ness · inferred

How we know: the VCSheet dataset · Not right? Tell us

Civilization Ventures Management, Llclisted by Civilization Ventures Management, LlcTiburon · $1M – $10M

How we know: Civilization Ventures Management, Llc's portfolio page · funding news · the VCSheet dataset · open dataset · 5k.vc investor directory · Not right? Tell us

e2vclisted by e2vc

How we know: e2vc's portfolio page · the VCSheet dataset · Not right? Tell us

Fifty Yearslisted by Fifty YearsSan Francisco · $250K – $2M

How we know: Fifty Years's portfolio page · the VCSheet dataset · open dataset · 5k.vc investor directory · Not right? Tell us

Frialelisted by FrialeNashville · $100K – $600Kvia Bryan Frist · inferred

How we know: Friale's portfolio page · open dataset · 5k.vc investor directory · Not right? Tell us

Hemisphere Ventures LLClisted by Hemisphere Ventures LLCMckinney

How we know: Hemisphere Ventures LLC's portfolio page · open dataset · 5k.vc investor directory · Not right? Tell us

HOF Capitallisted by HOF CapitalNew York · $500K – $10M

How we know: HOF Capital's portfolio page · a partner's Signal profile · Not right? Tell us

Hummingbird Ventureslisted by Hummingbird VenturesBrussels · $500K – $10M

How we know: Hummingbird Ventures's portfolio page · a partner's Signal profile · the VCSheet dataset · open dataset · 5k.vc investor directory · Not right? Tell us

Metaplanetlisted by MetaplanetTallinn · $500K – $10M

How we know: Metaplanet's portfolio page · the VCSheet dataset · Not right? Tell us

Neotribe Ventureslisted by Neotribe VenturesMenlo Park · $250K – $2M

How we know: Neotribe Ventures's portfolio page · Not right? Tell us

Norwest Venture Partnerslisted by Norwest Venture PartnersMenlo Park · $10M – $30M

How we know: a partner's Signal profile · open dataset · 5k.vc investor directory · Not right? Tell us

Oberland Capitallisted by Oberland CapitalNew York
Premji Investlisted by Premji InvestMenlo Park
Standard Capitallisted by Standard CapitalSan Francisco

How we know: Standard Capital's portfolio page · Not right? Tell us

Start Capitallisted by Start Capital
Time BioVentureslisted by Time BioVenturesSouthern California

How we know: Time BioVentures's portfolio page · Not right? Tell us

Toba Capitallisted by Toba CapitalLos Angeles · $1M – $10M

How we know: open dataset · 5k.vc investor directory · Not right? Tell us

UpHonest Capitallisted by UpHonest CapitalSilicon Valley · $50K – $1M

How we know: the VCSheet dataset · Not right? Tell us

Y Combinatorlisted by Y CombinatorSan Francisco · $500K

How we know: Y Combinator's portfolio page · the Y Combinator directory · open dataset · 5k.vc investor directory · Not right? Tell us

4DX VenturesreportedAccra · $50K – $500K

How we know: Y Combinator's founder network · Not right? Tell us

Abenteuer.Venturesreported

How we know: open dataset · 5k.vc investor directory · Not right? Tell us

Avlok CapitalreportedLynnwood

How we know: Y Combinator's founder network · Not right? Tell us

Four Rivers GroupreportedSan Francisco

How we know: Y Combinator's founder network · Not right? Tell us

IDrive Venturesreported

How we know: Y Combinator's founder network · Not right? Tell us

Libertus CapitalreportedLuxembourg

How we know: Y Combinator's founder network · Not right? Tell us

Lombardstreet VenturesreportedWoodside · $500K

How we know: the VCSheet dataset · Not right? Tell us

Paragon PartnersreportedMünchen

How we know: Y Combinator's founder network · Not right? Tell us

Wipro VenturesreportedBengaluru · $1M – $10M

How we know: Y Combinator's founder network · Not right? Tell us

Funding

SEC filings, press & company announcements

Source: company announcements and press reports — follow each round's link for the claim.

Founder mafia

3 people who came through BillionToOne went on to found or lead other companies.

Doktor GursonInvestor/AdvisorFounded Doblet +1Shahram Seyedin-NoorSeed-to-Scale Investor → IPOFounded InspirnaSonia SetayeshSeed-to-Scale Investor → IPOFounded Inspirna

Related companies · 7

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LabcorpLabCorp provides diagnostic testing services and clinical trial recruitment solutions that connect patient insights to drug development for healthcare providers.
Luminist LabsLuminist Labs provided a non-invasive test to identify and assess the progression of liver fibrosis and NASH in patients. The company was acquired by DiscernDx in 2020.
Helix NanotechnologiesHelix Nanotechnologies develops mRNA-based therapeutics for disease treatment and environmental applications, currently advancing a COVID-19 vaccine candidate for immunocompromised patients and testing interventions targeting climate challenges.
Sigma GeneticsSigma Genetics makes devices that use magnetic fields to introduce DNA, RNA, and other charged molecules into cells, offering advantages over electroporation including reduced arcing, better scalability, and reduced invasiveness for in vivo applications. The technology targets cell therapies, cancer drug delivery, DNA vaccines, biopharmaceutical manufacturing, and cosmetics.
NateraNatera develops genetic tests and diagnostics using cell-free DNA technology to detect diseases including cancers, genetic disorders, and transplant-related conditions. The company serves patients, physicians, and healthcare systems across oncology, women's health, and organ health.
Quest DiagnosticsQuest Diagnostics is the world's leading provider of diagnostic information services, serving one in three adult Americans and half of US physicians and hospitals. The company offers diagnostic insights and testing services to consumers and healthcare providers to support health decision-making.

Companies working in the same space as BillionToOne.

Non-dilutive funding · 1 SBIR/STTR award

Federal grants — no equity taken
AgencyPhaseYearAmount
National Institutes of Health (NIH)National Institutes of HealthPhase I2018$224.2K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

In the news

Leading Molecular Diagnostics Company BillionToOne Raises $130 Million in Oversubscribed Series D Funding Over $1B+ Valuationprnewswire.com · Jun 2024

Frequently asked questions

What does BillionToOne do?
BillionToOne is a precision diagnostics company that uses molecular counting technology to develop non-invasive prenatal screening and liquid biopsy tests for early disease detection. The company focuses on making molecular diagnostics accurate, fast, and accessible to patients.
Who founded BillionToOne?
BillionToOne was founded by Oguzhan Atay, David Tsao, Sukrit Silas in 2016.
Who are BillionToOne's investors?
BillionToOne's investors include 500 Emerging Europe, 500 Global, Asymmetry Ventures, Civilization Ventures Management, Llc, e2vc, Fifty Years, Friale, Hemisphere Ventures LLC and 22 more.
Is BillionToOne publicly traded?
Yes — BillionToOne trades on NASDAQ under the ticker BLLN.
Where is BillionToOne headquartered?
BillionToOne is headquartered in San Francisco, US.