SciFounders
Venture capitalSan Francisco · Pre-Seed–Series A · 3 people tracked
Also known as SCIFOUNDERS MANAGEMENT, LLC
Investment thesis
SciFounders supports strong technical leaders developing world-changing, research-intensive technologies, investing from pre-seed through Series A. Drawing on experience founding science companies such as Mammoth Bio and Conception, the firm aims to help more technical founders start and build impactful deep-science businesses. Through the SciFounder Fellowship it provides up to $1M in funding along with hands-on mentorship to help founders get started.
Source: firm website, verified Aug 25, 2026.
Team · 3 people
from the firm's website
Founder mafia
2 people who came through SciFounders went on to found or lead other companies.
What they invest in
from 16 of 21 portfolio companiesBiotech ×14Healthtech ×10Deep Tech ×9AI & Machine Learning ×5Medical Devices ×4Digital Health ×2Longevity ×2Advanced Manufacturing ×1
HQs:United States×7
Who they back
founder profiles across 8 portfolio companiesFounding team size:solo founder×32 founders×33 founders×2
Where their founders studiedfrom 11 founders with education data
The University of Texas at Dallas ×2
Where their founders worked beforefrom 10 founders with career history
Neuralink ×2OpenAI ×2University of California, San Francisco ×2
Accelerator rootsportfolio companies that came through a program
Investments · 21 tracked
founders shown can be your intro pathBy year:2026 · 12025 · 12 dated
Luminate develops medical device technology to address chemotherapy side effects, particularly hair loss and peripheral neuropathy, for oncology patients and healthcare providers.
BiotechDigital HealthHealthtechMedical DevicesGalway, US
Aaron Hannon(Founder)inBarbara Oliveira(Founder)inProf. Martin O'Halloran(Co-founder)inTOD FRANCIS(Director)ROBERT LISBONNE(Executive Officer, Director)SAAD KHAN(Director)
Co-investorsY Combinator8VCArtis VenturesFaberMetaplanetLachy Groom
Xterna develops xeno nucleic acid (XNA) technology to engineer cell-specific binders aimed at treating diseases currently considered untreatable.
BiotechDeep TechHealthtech
Co-investorsReinforced VenturesBoxOne Ventures
Conception develops stem cell technology to create functional reproductive cells in the laboratory, enabling in-vitro gametogenesis as a solution for individuals facing biological and medical fertility barriers.
BiotechDeep TechHealthtech
Matt Krisiloff(CEO)inBianka Seres(President)
Co-investorsage1CompoundHOF CapitalMetaplanetVU Venture Partners
Current Surgical develops a smart needle technology platform for surgical treatment of cancerous tumors.
Deep TechHealthtechMedical DevicesWashington, US
Co-investorsTrue VenturesCarbon SiliconDraper Associates
Deliver Biosciences develops a nanoparticle-based delivery platform to genetically engineer cells inside patients (in vivo) for cell and gene therapies, using programmable targeting to transport payloads such as DNA and mRNA to specific cell types.
BiotechDeep TechHealthtech
Earth AI uses AI to locate critical mineral deposits by analyzing geological data, supporting the supply chain for hardware and emerging technologies.
Advanced ManufacturingAI & Machine LearningClimate TechDeep TechNew MaterialsSan Francisco, US
Roman Teslyuk(Founder)in
BoardIan Rountree(Director)inMikhail Taver(Director)Jamie Lee(Director)inIsabella Sykes(Director)Arnoud Balhuizen(Director)
Co-investorsAirTree VenturesAlpaca VCBlackbird VenturesCantos VenturesCorigin VenturesDCVC (Data Collective)+12 more
EnduraTx develops small-molecule medicines that form permanent covalent bonds with disease-causing RNA to block production of proteins that cannot be drugged at the protein level, targeting conditions such as certain cancers and neurodegenerative diseases.
AI & Machine LearningBiotechDeep Tech
Co-investorsMoxxie VenturesScribble Ventures
EngageBio develops DNA-based medicines using proprietary non-viral delivery technology to achieve extended therapeutic expression from a single dose with low manufacturing complexity.
BiotechDigital HealthHealthtechSan Francisco, US
Will Olsen(Founder)in
Co-investorsMetaplanetWorldQuant VenturesY Combinator
Fletcher Bio engineers natural immune proteins using protein design to create precision immunotherapies that target and eliminate autoreactive T cells.
AI & Machine LearningBiotechDeep Tech
HarborSite develops a targeted gene insertion platform that engineers site-specific recombinase enzymes to integrate therapeutic genes into safe genomic sites.
BiotechDeep TechLongevity
Erik Aznauryan, PhD(Founder)in
Co-investorsFifty YearsSmartGateVC
Company started by the SciFounders team developing impactful technologies; has raised roughly $450M.
NewLimit develops epigenetic reprogramming medicines to extend healthspan and treat age-related diseases at the intersection of computer science and biotechnology.
AI & Machine LearningBiotechLongevitySouth San Francisco, US
Brian Armstrong(Co-founder, Board of Directors)inBlake Byers(Director)inJacob Kimmel(Director)inMichael Polansky(Executive Officer)
BoardZavain Dar(Director)in
Co-investorsS32Valor Equity Partners8VCAbstract Venturesage1Beyond Capital+6 more
Olio Labs develops drug combination therapies using machine learning to identify treatments that target multiple interacting proteins simultaneously, with initial candidates focused on obesity treatment.
BiotechHealthtech
David Tingley(Founder)inTom Roseberry(Founder)in
Co-investorsOverwater Ventures LlcScrum VenturesY CombinatorZAKA VC
Preventive.bio focuses on preventing disease before birth.
BiotechFemTechHealthtech
Co-investorsHOF Capital
Co-investorsFifty Years
Trace Biosciences develops targeted fluorescent imaging agents, called Nerve Trace, that highlight nerves in real time during surgery so surgeons and surgical robots can avoid nerve damage.
BiotechHealthtechMedical DevicesBeaverton, US
Connor Barth(Executive Officer, Director)Summer Gibbs(Executive Officer, Director)Lei Wang(Executive Officer, Director)Jonathan Sorger(Director)
Co-investorsElevate Capital
Velorium develops transformational medicines by combining scientific research with patient-focused collaboration.
BiotechHealthtechMedical DevicesSan Francisco, US
Pouya Modareszadeh(Founder)inParsa Modareszadeh(Founder)in
Co-investorsMetaplanetMyAsiaVCY Combinator468 CapitalRitual Capital
Portfolio news
latest coverage across their companiesEndura · discoveryalert.com.au · Aug 13, 2026
Preventive · hindustantimes.com · Aug 11, 2026
Trace Bio · newswise.com · Aug 1, 2026
Luminate · luminatedata.com · Jul 15, 2026
Conception · medscape.com · Nov 8, 2025
Olio Labs · citybiz.co · Mar 21, 2025
Frequently asked questions
- How many investments has SciFounders made?
- SciFounders has 21 tracked investments, 1 of which have exited via acquisition or IPO, including 2 dated in the last 24 months.
- What stage does SciFounders invest at?
- SciFounders invests at the Pre-Seed, Seed, Series A stages.
- What is SciFounders's typical check size?
- SciFounders typically writes checks of $1M.
- What sectors does SciFounders focus on?
- SciFounders focuses on Biotech, Deep Tech.
- Where is SciFounders located?
- SciFounders is headquartered in San Francisco, US.
- Does SciFounders lead rounds?
- SciFounders typically participates in rounds rather than leading them.
- Who does SciFounders co-invest with?
- SciFounders most often shares deals with Metaplanet, Y Combinator, Fifty Years, among 39 tracked co-investors.
Images
Co-investors · 1
Sequoia Capital is a venture capital firm that partners with founders to build technology companies.
Firms observed investing alongside SciFounders, from public investor directories. Shared companies are the overlap with SciFounders's recorded portfolio.
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