/Investor DB

SciFounders

Venture capital

San Francisco · Pre-Seed–Series A · 4 people tracked

Also known as SCIFOUNDERS MANAGEMENT, LLC

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Investment thesis

SciFounders supports strong technical leaders developing world-changing, research-intensive technologies, investing from pre-seed through Series A. Drawing on experience founding science companies such as Mammoth Bio and Conception, the firm aims to help more technical founders start and build impactful deep-science businesses. Through the SciFounder Fellowship it provides up to $1M in funding along with hands-on mentorship to help founders get started.

Source: firm website, verified Sep 29, 2026.

Stage
Pre-Seed–Series A
Check
$1M
HQ
San Francisco, CA, US
Leads rounds
Follows
Instruments
Equity
Founded
2021
Last 12 months
3 investments
Private fund assets
$22.7M
VC funds
2
Tracked investments
22
Unicorns
1
Acquisitions
1

Team · 4 people

from the firm's website & public directories

Founder mafia

2 people who came through SciFounders went on to found or lead other companies.

What they invest in

from 18 of 22 portfolio companies

Biotech ×16Deep Tech ×10Healthtech ×10AI & Machine Learning ×6Medical Devices ×5Advanced Manufacturing ×2Climate Tech ×2Digital Health ×2

HQs:United States×10

Who they back

founder profiles across 11 portfolio companies
18%
solo founders
2 of 11 mapped founding teams
33%
repeat founders
of 15 founders with career history

Founding team size:solo founder×22 founders×63 founders×24+ founders×1

Where their founders studiedfrom 15 founders with education data

University of Cambridge ×3The University of Texas at Dallas ×2

What their founders studiedfrom 15 founders with field-of-study data

Life Sciences ×10Engineering ×5

Where their founders worked beforefrom 15 founders with career history

IBM ×2MRC Laboratory of Molecular Biology (LMB) ×2OpenAI ×2University of California, San Francisco ×2

Accelerator rootsportfolio companies that came through a program

Y Combinator ×5

Investments · 22 tracked

founders shown can be your intro path

By year:2026 · 22025 · 22024 · 15 dated

Luminateluminatemed.comin𝕏Seed · Jan 2026 · $21M✓ verified

Luminate develops medical device technology to address chemotherapy side effects, particularly hair loss and peripheral neuropathy, for oncology patients and healthcare providers.

BiotechDigital HealthHealthtechMedical DevicesGalway, US

Aaron Hannon(Founder)inBarbara Oliveira(Founder)inProf. Martin O'Halloran(Co-Founder)JAMES EVERINGHAM(Executive Officer, Director)Eldad Livni(Founder)Leonid Belkind(Founder)

Co-investorsY Combinator8VCArtis VenturesAtlantic Bridge VenturesFaberMetaplanet+12 more

Xternaxterna.bioin✓ verified

Xterna develops xeno nucleic acid (XNA) technology to engineer cell-specific binders aimed at treating diseases currently considered untreatable.

BiotechDeep TechHealthtech

Jessica Corry(Founder)inChris Wan(Founder)in

Co-investorsReinforced VenturesBoxOne Ventures

Alga Biosciencesalga.bioin𝕏Seed

Alga Biosciences develops feed additives that reduce methane emissions from cattle — cutting cow burps to combat climate change.

Advanced ManufacturingAgTechBiotechClimate TechSan Francisco, US

Alex Brown(Founder)inDaria Balatsky(Founder)inCaroline McKeon(Founder)inAlexander Brown(Founder)in

Co-investorsY CombinatorDay One VenturesAngel Collective Opportunity FundBBQ CapitalCollaborative FundCool Climate Collective+13 more

Coherence Neurocoherenceneuro.comin𝕏Seed · Nov 2025 · $10M

Coherence develops neurotechnology systems that measure and modulate brain activity to treat cancer and other neurological diseases.

AI & Machine LearningBiotechMedical DevicesSan Francisco, US

Ben Woodington(Founder)inElise Jenkins(Founder)in

Co-investorsArtesianASDF VenturesBlackbird VenturesDivergent CapitalEmpath VenturesIrregular Expressions+5 more

Conception Bioconception.bioin

Conception develops stem cell technology to create functional reproductive cells in the laboratory, enabling in-vitro gametogenesis as a solution for individuals facing biological and medical fertility barriers.

BiotechDeep TechHealthtechBerkeley, US

Matt Krisiloff(CEO)inBianka Seres(President)in

Co-investorsage1CompoundHOF CapitalMaiora Rebel VenturesMetaplanetVU Venture Partners

Current Surgicalcurrentsurgical.comin𝕏

Current Surgical develops a smart needle technology platform for surgical treatment of cancerous tumors.

Deep TechHealthtechMedical DevicesWashington, US

Al Mashal, Ph.D.(CEO / CoFounder)Chris Wagner, Ph.D.(CTO / CoFounder)

Co-investorsTrue VenturesCarbon SiliconDraper AssociatesMBX Capital

Deliverbiodeliverbio.comin𝕏

Deliver Biosciences develops a nanoparticle-based delivery platform to genetically engineer cells inside patients (in vivo) for cell and gene therapies, using programmable targeting to transport payloads such as DNA and mRNA to specific cell types.

BiotechDeep TechHealthtech

EARTH AIearth-ai.comin𝕏

Earth AI uses AI to locate critical mineral deposits by analyzing geological data, supporting the supply chain for hardware and emerging technologies.

Advanced ManufacturingAI & Machine LearningClimate TechDeep TechNew MaterialsSan Francisco, US

Roman Teslyuk(Founder)inRoman(Founder)

BoardIan Rountree(Director)inMikhail Taver(Director)inJamie Lee(Director)inIsabella Sykes(Director)

Co-investorsAirTree VenturesAlpaca VCBlackbird VenturesCantos VenturesCorigin VenturesDCVC (Data Collective)+25 more

Enduraenduratx.cominSep 2024

EnduraTx develops small-molecule medicines that form permanent covalent bonds with disease-causing RNA to block production of proteins that cannot be drugged at the protein level, targeting conditions such as certain cancers and neurodegenerative diseases.

AI & Machine LearningBiotechDeep Tech

Co-investorsMoxxie VenturesScribble VenturesTrue VenturesCalm Ventures

Engage Bioengagebio.cominSeedAcquired

EngageBio develops DNA-based medicines using proprietary non-viral delivery technology to achieve extended therapeutic expression from a single dose with low manufacturing complexity.

BiotechDigital HealthHealthtechSan Francisco, US

Will Olsen(Founder)inKathryn Kwant

Co-investorsCAL InnovationCalifornia Innovation FundMetaplanetVentureSouqWorldQuant VenturesY Combinator+9 more

Fletcherbiofletcherbio.comin

Fletcher Bio engineers natural immune proteins using protein design to create precision immunotherapies that target and eliminate autoreactive T cells.

AI & Machine LearningBiotechDeep Tech

Harborsiteharborsite.comin𝕏

HarborSite develops a targeted gene insertion platform that engineers site-specific recombinase enzymes to integrate therapeutic genes into safe genomic sites.

BiotechDeep TechLongevity

Erik Aznauryan, PhD(Founder)in

Co-investorsFifty YearsSmartGateVC

Moabtxmoabtx.bioin

MOAB develops minibinders — small, stable, modular protein binders based on natural scaffolds — for use as new therapeutics.

AI & Machine LearningBiotechDeep Tech

NewLimitnewlimit.com𝕏May 2025

NewLimit develops epigenetic reprogramming medicines to extend healthspan and treat age-related diseases at the intersection of computer science and biotechnology.

AI & Machine LearningBiotechLongevitySouth San Francisco, US

Brian Armstrong(Founder)inBlake Byers(Founder)inJacob Kimmel(Founder)inMichael Polansky(Executive Officer)

BoardZavain Dar(Director)in

Co-investorsS32Valor Equity Partners8VCAbstract Venturesage1Beyond Capital+15 more

Olio Labsoliolabs.coinSeed

Olio Labs develops drug combination therapies using machine learning to identify treatments that target multiple interacting proteins simultaneously, with initial candidates focused on obesity treatment.

BiotechHealthtech

David Tingley(Founder)inTom Roseberry(Founder)inTim Krausz(Lead Research Engineer)

Co-investorsOverwater Ventures LlcPioneerScrum VenturesY CombinatorZAKA VC

Preventivepreventive.bioin𝕏

Preventive.bio focuses on preventing disease before birth.

BiotechFemTechHealthtech

Co-investorsHOF Capital

Trace Biotrace-bio.cominJul 2026

Trace Biosciences develops technology to make nerves visible in real time during surgical procedures, enabling surgeons to better identify and preserve nerve structures.

BiotechDeep TechHealthtechMedical DevicesBeaverton, US

Connor Barth(Cofounder & CEO)inSummer Gibbs(Cofounder & CSO)Lei Wang(Cofounder & CTO)Jonathan Sorger(Director)

Co-investorsElevate Capital

Velorum Therapeuticsvelorumtx.comin𝕏Seed

Velorium develops transformational medicines by combining scientific research with patient-focused collaboration.

BiotechHealthtechMedical DevicesSan Francisco, US

Pouya Modareszadeh(CEO)inParsa Modareszadeh(COO)in

Co-investorsEight CapitalMetaplanetMyAsiaVCTranspose Platform ManagementY Combinator468 Capital+6 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Fluorescent-guided surgeryIn vivo cell editingMammoth BioSculpta

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has SciFounders made?
SciFounders has 22 tracked investments, 1 of which have exited, including 4 dated in the last 24 months.
What stage does SciFounders invest at?
SciFounders invests at the Pre-Seed, Seed, Series A stages.
What is SciFounders's typical check size?
SciFounders typically writes checks of $1M.
What sectors does SciFounders focus on?
SciFounders focuses on Biotech, Deep Tech.
Where is SciFounders located?
SciFounders is headquartered in San Francisco, US.
Does SciFounders lead rounds?
SciFounders typically participates in rounds rather than leading them.
Who does SciFounders co-invest with?
SciFounders most often shares deals with Metaplanet, Y Combinator, Fifty Years, among 56 tracked co-investors.

Images

SciFounders photo

Co-investors · 1

Sequoia Capital

Sequoia Capital is a venture capital firm that partners with founders to build technology companies.

$100K – $50M

Firms observed investing alongside SciFounders, from public investor directories. Shared companies are the overlap with SciFounders's recorded portfolio.

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