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SciFounders

San Francisco · Pre-Seed–Series A · 3 people tracked

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Investment thesis

SciFounders focuses on backing technical founders building research-heavy companies with transformative potential. The firm brings deep experience in building science-focused ventures, evidenced by prior company-building successes. The firm supports founders from the earliest stages through Series A and offers structured mentorship and capital via its fellowship program to accelerate technology development and commercialization.

Invests inDeep TechSan Francisco

Source: firm website, verified Jul 20, 2026.

Stage
Pre-Seed–Series A
Check
$1M
HQ
San Francisco, US
Tracked investments
5

Team · 3 people

from the firm's website
Alexander Schubert· Co-founder

PhD in Molecular Biology from University of Cambridge with research focused on alternative causes of neurodegeneration. Previously worked in the Research & Early Development group at Genentech before co-founding SciFounders.

Lucas Harrington· Co-founder and CSO

Co-founder and Chief Scientific Officer of Mammoth Biosciences, developing next-generation CRISPR gene editing therapies. Holds a PhD in Biochemistry from UC Berkeley, where he studied in the laboratory of Nobel Laureate Jennifer Doudna.

Matt Krisiloff· CEO

CEO of Conception, a company focused on converting pluripotent stem cells into viable human eggs. Previously served as director of Y Combinator Research and was a founding team member of OpenAI, with advisory and investment experience across over 150 startups.

What they invest in

from 2 of 5 portfolio companies

Biotech ×2Digital Health ×2Healthtech ×2Medical Devices ×1

HQs:United States×2

Investments · 5 tracked

founders shown can be your intro path
Luminateluminatemed.comin𝕏✓ verified

Luminate develops medical device technology to address chemotherapy side effects, particularly hair loss and peripheral neuropathy, for oncology patients and healthcare providers. The company is advancing clinical-stage devices while supporting cancer patients, clinicians, and health systems.

BiotechDigital HealthHealthtechMedical DevicesGalway, US

Aaron Hannon(Co-founder)inBarbara Oliveira(Founder)inDr. Bárbara Oliveira(Co-founder)Prof. Martin O'Halloran(Co-founder)

Engage Bioengagebio.comin𝕏

EngageBio develops DNA-based medicines using proprietary non-viral delivery technology to achieve extended therapeutic expression from a single dose with low manufacturing complexity.

BiotechDigital HealthHealthtechSan Francisco, US

Will Olsen(Founder)in

Fluorescent-guided surgery
In vivo cell editing
The future of cancer care

Frequently asked questions

What stage does SciFounders invest at?
SciFounders invests at the Pre-Seed, Series A stages.
What is SciFounders's typical check size?
SciFounders typically writes checks of $1M.
What sectors does SciFounders focus on?
SciFounders focuses on Deep Tech.
Where is SciFounders located?
SciFounders is headquartered in San Francisco, US.

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