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LongeVC

Venture capitalActively deploying

Washington D.C. · Pre-Seed–Series A · 39 people tracked

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Investment thesis

LongeVC invests in early-stage biotech and longevity companies working toward an ageless future. Its focus areas include pre-clinical and clinical stage drug development companies studying the molecular and cellular mechanisms of aging, early-stage firms building solutions for personalized medicine and advanced diagnostics, and foundational platform technologies and integrated healthcare solutions that enable faster, scalable drug discovery and testing. The firm supports founders by connecting them with a global network of thought leaders and curating an ecosystem of longevity-focused companies.

Source: firm website, verified Aug 3, 2026.

Stage
Pre-Seed–Series A
HQ
Washington D.C., CA, US
Instruments
Equity
Tracked investments
30

Team · 39 people

from the firm's website
Greg Fishman· Venture Partner
John Mikhael· Advisory Board

What they invest in

from 23 of 30 portfolio companies

Biotech ×17Healthtech ×12AI & Machine Learning ×10Medical Devices ×9Deep Tech ×7Longevity ×6Digital Health ×5Wellness & Fitness ×2

HQs:United States×9Switzerland×2

Investments · 30 tracked

founders shown can be your intro path
PreCombprecomb.comin✓ verified

PreComb is a Swiss biotech company developing its proprietary 3DTwin technology, which combines automated drug testing on patient-derived tumor twins with AI-guided data analysis and response prediction.

AI & Machine LearningBiotechHealthtechMedical Devices

Aniani.ai
AOA Dxaoadx.comin𝕏

AOA Dx develops a blood-based liquid biopsy platform using mass spectrometry and machine learning to detect ovarian cancer at early stages through tumor-associated biomarkers in serum.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesDenver, US

Oriana Papin-Zoghbi(Founder)inAlex Fisher(Founder/COO)inAnna Jeter(Founder)inAbigail Mcelhinny(Executive Officer)Oriana Zoghbi-Harb(Executive Officer, Director)

BoardSurbhi Sarna(Director)

Basepawsbasepaws.comin
Catena Biosciencescatenabiosciences.comin𝕏

Catena develops a conjugation platform for antibody-drug conjugates (ADCs) and multi-payload conjugates used in oncology for solid tumors.

BiotechDeep TechHealthtechMedical DevicesSan Francisco, US

Marco Lobba(Founder)inMatthew Francis(Founder)in

CatenaBiocatenabio.comin

Catena Biosciences develops therapeutics using its CysTyr conjugation platform to create Multi-Payload Conjugates (MPCs), a next-generation form of antibody-drug conjugate that delivers dual payloads.

BiotechHealthtechBerkeley, US

Constructive Bioconstructive.bioin𝕏

Constructive develops synthetic biology technology using recoded genomes and engineered tRNAs to incorporate novel chemical building blocks into proteins, enabling new therapeutics, materials, and manufacturing applications.

BiotechDeep TechNew Materials

Deep Longevitydeeplongevity.comin𝕏

Deep Longevity develops AI-powered aging clocks that predict biological age using blood, DNA, microbiome, and behavioral data to provide personalized health insights and recommendations.

AI & Machine LearningHealthtechLongevity

First Longevity

Brings together innovators and investors to support companies forming the longevity economy.

Firstlongevityfirstlongevity.comin𝕏

First Longevity operates a longevity-focused platform, including a daily newsletter covering longevity science, investment, and innovation, and DLT, a data system that tracks longevity companies, signals, and trends.

Data & InfrastructureLongevityMedia & Entertainment

Freedom Biosciencesfreedombio.coin𝕏

Freedom Biosciences develops neuropsychiatric therapeutics, focusing on novel treatments for conditions including depression, PTSD, and alcoholism.

BiotechDigital HealthMental Health

Dr. John Krystal(Co-founder & CEO)Dina Burkitbayeva(Co-founder)

Glyphic Biotechnologiesglyphic.bioin𝕏

Glyphic Biotechnologies develops ProSE™, a high-throughput de novo protein sequencing technology for analyzing proteomes with single-molecule sensitivity.

BiotechDeep TechBerkeley, US

Joshua Yang(Founder & CEO)Daniel Estandian(Founder)Ed Boyden(Founder)Craig Asher(Director)Jimmy Yun(Director)

Hauthaut.aiin𝕏

Haut.AI develops LIQA (Live Image Quality Assurance), a smart image capture technology that guides users to take high-quality selfies for AI-based skin analysis by providing real-time feedback on face position, angle, lighting, and framing.

AI & Machine LearningHealthtechWellness & Fitness

Helix Nanotechnologieshelixnano.comin𝕏

Helix Nanotechnologies develops mRNA-based therapeutics for disease treatment and environmental applications, currently advancing a COVID-19 vaccine candidate for immunocompromised patients and testing interventions targeting climate challenges.

AI & Machine LearningBiotechHealthtechBoston, US

Nikolai Eroshenko(Founder/CSO)in

Insilicoinsilico.comin𝕏
Insilico Medicinein𝕏

Uses artificial intelligence innovations to bridge biomarker development and drug discovery.

BiotechBaltimore, US

Aleksandrs Zavoronkovs(Executive Officer, Director)

Longenesislongenesis.comin

Longenesis operates a platform for health and biomedical data management used to run research studies, including managing study participants across the Baltics and Mediterranean regions.

BiotechCrypto & Web3Digital HealthHealthtech

Longevitylongevity.foundationin𝕏

The Longevity Science Foundation is a nonprofit organization that funds fundamental research on healthy aging, awarding grants to academic institutions for longevity studies.

BiotechImpact & Social GoodLongevityZug, CH

Longevitybiotechlongevitybiotech.org𝕏

The Longevity Biotechnology Association is a global membership organization representing leaders in geroscience and gerotherapeutics, focused on developing medicines and therapies to prevent and cure age-related health conditions.

BiotechLongevity

Medici Therapeutics

Develops in-vivo TCR therapies, cancer vaccines, and genetic rejuvenation tools to treat cancer and reverse age-related decline.

Meliomelio.tech

Melio develops rapid diagnostic technology for bloodborne infections in neonatal care using microfluidics and machine learning, delivering results significantly faster than traditional blood cultures.

AI & Machine LearningDeep TechMedical Devices

ProtonIntelprotonintelligence.comin

Proton Intelligence develops CKM™, a continuous monitoring medical device drawing on biosensing and minimally invasive microdevice technology for clinical use.

Deep TechDigital HealthHealthtechMedical Devices

Paul(Veteran IVD technologist)Bill

Red Queen Bioredqueen.bio

Red Queen Bio builds an AI-powered biodefense system that rapidly designs and manufactures countermeasures against emerging biological threats, enabling faster defensive responses to evolving pathogenic risks.

AI & Machine LearningBiotechDefense Tech

Hannu Rajaniemi(Executive Director)Nikolai Eroshenko(CEO)

Rubedo Life Sciencesrubedolife.comin

Rubedo Life Sciences develops therapeutics targeting aging by eliminating senescent cells to extend human healthspan.

AI & Machine LearningBiotechLongevityMedical Devices

SiPhox Healthsiphoxhealth.comin𝕏

Siphox Health develops early diagnostic testing technology to detect and manage chronic diseases at home, delivered as a painless 5-minute test that enables frequent monitoring.

Digital HealthHealthtechLongevityMedical DevicesWellness & FitnessBoston, US

Michael Dubrovsky(Co-Founder)inDiedrik Vermeulen(Founder)in

The Longevity Biotech Association

A consortium aiming to advance the longevity industry by setting standards, educating stakeholders, and encouraging partnerships.

The Longevity Science Foundation

International non-profit funding early-stage research on extending the healthy human lifespan.

Trogenixtrogenix.comin

Trogenix develops precision gene therapies for cancer using its Odysseus platform and Synthetic Super-Enhancer (SSE) technology, engineered DNA elements activated only in diseased cell states to selectively target and kill tumour cells while triggering an immune response.

BiotechDeep TechHealthtech

Unnatural Productsunnaturalproducts.comin𝕏

Unnatural Products is a drug discovery platform company that develops synthetic macrocycles to target previously undruggable disease targets.

AI & Machine LearningBiotechDeep TechMedical DevicesSanta Cruz, US

Cameron Pye(Co-Founder & CEO)Joshua Schwochert(Co-Founder & CSO)Vasudev Bailey(Director)

Valink Therapeuticsvalinktx.comin𝕏

Valink Therapeutics develops bispecific antibody-drug conjugates (ADCs) for therapeutic applications, combining high-throughput discovery, antibody engineering, and medicinal chemistry capabilities.

AI & Machine LearningBiotechHealthtechMedical DevicesBoston, US

Arne Scheu(Founder)inIrsyad Khairil(Founder)in

Frequently asked questions

What stage does LongeVC invest at?
LongeVC invests at the Pre-Seed, Seed, Series A stages.
What sectors does LongeVC focus on?
LongeVC focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
Where is LongeVC located?
LongeVC is headquartered in Washington D.C., US.

Media · Podcasts & interviews

featuring the team

🚀 Investing in the Future of Health: Insights from Sergey Jakimov & LongeVC 🔬

Peggy Van de Plassche · Sergey Jakimov

E09: Revolutionizing Biotech Investment | Exclusive Interview with LongeVC's Sergey Jakimov 🌟

HasanTarek POD · Sergey Jakimov

Investing in the Age of Longevity 2022 – Sergey Jakimov – LongeVC

Master Investor · Sergey Jakimov

595th 1Mby1M Roundtable with Sergey Jakimov, LongeVC

1Mby1M Roundtables · Sergey Jakimov

Images

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