LongeVC
Venture capitalActively deployingWashington D.C. · Pre-Seed–Series A · 39 people tracked
Investment thesis
LongeVC invests in early-stage biotech and longevity companies working toward an ageless future. Its focus areas include pre-clinical and clinical stage drug development companies studying the molecular and cellular mechanisms of aging, early-stage firms building solutions for personalized medicine and advanced diagnostics, and foundational platform technologies and integrated healthcare solutions that enable faster, scalable drug discovery and testing. The firm supports founders by connecting them with a global network of thought leaders and curating an ecosystem of longevity-focused companies.
Source: firm website, verified Aug 17, 2026.
Team · 39 people
from the firm's websiteWhat they invest in
from 26 of 29 portfolio companiesBiotech ×20Healthtech ×13AI & Machine Learning ×12Medical Devices ×9Deep Tech ×7Longevity ×7Digital Health ×5Wellness & Fitness ×2
HQs:United States×10Switzerland×2
Who they back
founder profiles across 12 portfolio companiesFounding team size:solo founder×42 founders×64+ founders×2
Where their founders studiedfrom 10 founders with education data
University of Oxford ×2
Where their founders worked beforefrom 11 founders with career history
Parsagen Diagnostics, Inc. ×2
Accelerator rootsportfolio companies that came through a program
Investments · 29 tracked
founders shown can be your intro pathBy year:2025 · 12024 · 12019 · 13 dated
PreComb is a Swiss biotech company developing its proprietary 3DTwin technology, which combines automated drug testing on patient-derived tumor twins with AI-guided data analysis and response prediction.
AI & Machine LearningBiotechHealthtechMedical Devices
Co-investorsKinled Holding
ANI.AI is a San Francisco research lab building a computational platform for longevity medicine that integrates deep multiomics, longitudinal digital phenotyping, and physician-supervised intervention into a unified model of an individual's biological state.
AI & Machine LearningBiotechLongevitySan Francisco, US
Bruno Balen(Co-Founder, Co-CEO)Nika Pintar(Co-Founder, Co-CEO)
Co-investorsUntapped Ventures
AOA Dx develops a blood-based liquid biopsy platform using mass spectrometry and machine learning to detect ovarian cancer at early stages through tumor-associated biomarkers in serum.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesDenver, US
Oriana Papin-Zoghbi(Founder)inAlex Fisher(Founder/COO)inAnna Jeter(Founder)inOriana Zoghbi-Harb(Executive Officer, Director)Abigail Mcelhinny(Executive Officer)
BoardSurbhi Sarna(Director)
Co-investorsAlleyCorpGood Growth CapitalJoyance PartnersY CombinatorAstiaAurum Venture Partners+18 more
Basepaws offers at-home DNA test kits for cats and dogs, using an oral swab to provide digital reports on breed mix, genetic health markers, oral health, and physical traits.
BiotechConsumerDirect to Consumer
Co-investorsBand of AngelsChloe CapitalIrishAngelsPasadena AngelsGingerbread CapitalInertia Ventures
Catena develops a conjugation platform for antibody-drug conjugates (ADCs) and multi-payload conjugates used in oncology for solid tumors.
BiotechDeep TechHealthtechMedical DevicesSan Francisco, US
Marco Lobba(Founder)inMatthew Francis(Founder)in
Co-investorsCivilization Ventures Management, LlcIaso VenturesY CombinatorAxial VCMBX CapitalSocial Impact Capital
Catena Biosciences develops therapeutics using its CysTyr conjugation platform to create Multi-Payload Conjugates (MPCs), a next-generation form of antibody-drug conjugate that delivers dual payloads.
BiotechHealthtechBerkeley, US
Co-investorsFREEFLOWNYBC Ventures
Constructive Bio is a biotechnology company that rewrites the genetic code to give cells access to non-canonical amino acid building blocks, expanding the range of proteins that can be designed, engineered, and manufactured.
BiotechDeep TechNew Materials
Jason Chin(Professor)
Co-investors+ND CapitalAmadeus Capital PartnersFine Structures VenturesGENERAL INCEPTIONOMX VenturesPaladin Capital Group+2 more
Deep Longevity develops AI-powered aging clocks that predict biological age using blood, DNA, microbiome, and behavioral data to provide personalized health insights and recommendations.
AI & Machine LearningHealthtechLongevity
Co-investorsBold Capital PartnersKickstart Innovation
First Longevity operates a longevity-focused platform, including a daily newsletter covering longevity science, investment, and innovation, and DLT, a data system that tracks longevity companies, signals, and trends.
Data & InfrastructureLongevityMedia & Entertainment
Freedom Biosciences develops neuropsychiatric therapeutics, focusing on novel treatments for conditions including depression, PTSD, and alcoholism.
BiotechDigital HealthMental Health
Dr. John Krystal(Co-founder & CEO)inDina Burkitbayeva(Co-founder)in
Co-investorsBeni Venture CapitalIter InvestmentsManta Ray VenturesPsyMed VenturesUnruly CapitalMBX Capital
Glyphic Biotechnologies develops ProSE™, a high-throughput de novo protein sequencing technology for analyzing proteomes with single-molecule sensitivity.
BiotechDeep TechBerkeley, US
Joshua Yang(Founder & CEO)Daniel Estandian(Founder)Ed Boyden(Founder)Josh Yang(Founder)in
BoardCraig Asher(Director)inJimmy Yun(Director)
Co-investorsArtis VenturesBlack FlagCivilization Ventures Management, LlcFoundersX VenturesModi VenturesOMX Ventures+3 more
Haut.AI develops LIQA (Live Image Quality Assurance), a smart image capture technology that guides users to take high-quality selfies for AI-based skin analysis by providing real-time feedback on face position, angle, lighting, and framing.
AI & Machine LearningHealthtechWellness & Fitness
Helix Nanotechnologies develops mRNA-based therapeutics for disease treatment and environmental applications, currently advancing a COVID-19 vaccine candidate for immunocompromised patients and testing interventions targeting climate challenges.
AI & Machine LearningBiotechHealthtechBoston, US
Nikolai Eroshenko(Founder/CSO)in
Co-investorsBascom VenturesBeast VenturesChampion Hill VenturesDCVC (Data Collective)Fifty YearsHAWKTAIL+8 more
This page is a thought-leadership essay by Teymour Boutros-Ghali of Bold Capital Partners arguing that venture investors and foundations should fund the commercialization phase of health-equity-focused life science companies using non-dilutive capital.
BiotechBaltimore, US
Aleksandrs Zavoronkovs(Executive Officer, Director)
Co-investorsB Capital GroupBold Capital PartnersBOLD LongevityHarmonix FundSquareOne Capital
Insilico Medicine applies computational and AI-based modeling to drug design and problems such as protein folding for pharmaceutical research and development.
AI & Machine LearningBiotechHealthtechHong Kong
Alex Zhavoronkov(Founder & CEO)Lennart Lee(Director)Alex Zavoronkov(Director)James Mellon(Director)
BoardNisa Leung(Director)
Co-investorsB Capital GroupB4 CapitalBOLD LongevityF-Prime CapitalGestio CapitalLAV+5 more
Longenesis operates a platform for health and biomedical data management used to run research studies, including managing study participants across the Baltics and Mediterranean regions.
BiotechCrypto & Web3Digital HealthHealthtech
The Longevity Biotechnology Association is a global membership organization representing leaders in geroscience and gerotherapeutics, focused on developing medicines and therapies to prevent and cure age-related health conditions.
BiotechLongevity
Develops in-vivo TCR therapies, cancer vaccines, and genetic rejuvenation tools to treat cancer and reverse age-related decline.
Melio develops rapid diagnostic technology for bloodborne infections in neonatal care using microfluidics and machine learning, delivering results significantly faster than traditional blood cultures.
AI & Machine LearningDeep TechMedical Devices
Co-investorsCove FundLexi Ventures
Proton Intelligence develops CKM™, a continuous monitoring medical device drawing on biosensing and minimally invasive microdevice technology for clinical use.
Deep TechDigital HealthHealthtechMedical Devices
Co-investors15th RockAIN VenturesTenmile
Red Queen Bio builds an AI-powered biodefense system that rapidly designs and manufactures countermeasures against emerging biological threats, enabling faster defensive responses to evolving pathogenic risks.
AI & Machine LearningBiotechDefense Tech
Hannu Rajaniemi(Executive Director)Nikolai Eroshenko(CEO)
Co-investorsCompoundThe Venture CollectiveCerberus VenturesFifty Years
Rubedo Life Sciences develops therapeutics targeting aging by eliminating senescent cells to extend human healthspan.
AI & Machine LearningBiotechLongevityMedical Devices
Co-investorsBeiersdorf Innovation FundCDP Venture CapitalEvolution VenturesKhosla VenturesModi VenturesMoonstone Venture Capital+1 more
Siphox Health develops early diagnostic testing technology to detect and manage chronic diseases at home, delivered as a painless 5-minute test that enables frequent monitoring.
Digital HealthHealthtechLongevityMedical DevicesWellness & FitnessBoston, US
Michael Dubrovsky(Co-Founder)inDiedrik Vermeulen(Founder)in
Co-investorsDuke Capital PartnersNeer Venture PartnersOverlap HoldingsY CombinatorBalaji SrinivasanInflect Health+4 more
A consortium aiming to advance the longevity industry by setting standards, educating stakeholders, and encouraging partnerships.
International non-profit funding early-stage research on extending the healthy human lifespan.
Trogenix develops precision gene therapies for cancer using its Odysseus platform and Synthetic Super-Enhancer (SSE) technology, engineered DNA elements activated only in diseased cell states to selectively target and kill tumour cells while triggering an immune response.
BiotechDeep TechHealthtech
Co-investorsACADEMY INVESTORAIN Ventures
Unnatural Products is a drug discovery platform company that develops synthetic macrocycles to target previously undruggable disease targets.
AI & Machine LearningBiotechDeep TechMedical DevicesSanta Cruz, US
Cameron Pye(Co-Founder & CEO)inJoshua Schwochert(Co-Founder & CSO)
BoardVasudev Bailey(Director)in
Co-investorsAbstract VenturesArtis VenturesAsset Management CompanyBetter Ventures Central LlcBlue Bear VenturesDroia Ventures+6 more
Valink Therapeutics develops bispecific antibody-drug conjugates (ADCs) for therapeutic applications, combining high-throughput discovery, antibody engineering, and medicinal chemistry capabilities.
AI & Machine LearningBiotechHealthtechMedical DevicesBoston, US
Arne Scheu(Founder)inIrsyad Khairil(Founder)in
Co-investorsHoxton VenturesMetaplanetOxonian VenturesP53 InvestSynBioVenY Combinator+1 more
Portfolio news
latest coverage across their companies

SiPhox Health · ycombinator.com · Jun 3, 2026
Rubedo Life Sciences · fightaging.org · Apr 8, 2026
Basepaws · finance.yahoo.com · Mar 5, 2026
Red Queen Bio · news.crunchbase.com · Mar 4, 2026
Valink Therapeutics · finsmes.com · Oct 20, 2025
Frequently asked questions
- How many investments has LongeVC made?
- LongeVC has 28 tracked investments, including 1 dated in the last 24 months.
- What stage does LongeVC invest at?
- LongeVC invests at the Pre-Seed, Seed, Series A stages.
- What sectors does LongeVC focus on?
- LongeVC focuses on AI & Machine Learning, Biotech, Digital Health, FemTech, Healthtech, Longevity, Medical Devices, Mental Health, Wellness & Fitness.
- Where is LongeVC located?
- LongeVC is headquartered in Washington D.C., US.
- Who does LongeVC co-invest with?
- LongeVC most often shares deals with Y Combinator, The Venture Collective, Artis Ventures, among 94 tracked co-investors.
Media · Podcasts & interviews
featuring the team🚀 Investing in the Future of Health: Insights from Sergey Jakimov & LongeVC 🔬
Peggy Van de Plassche · Sergey Jakimov
E09: Revolutionizing Biotech Investment | Exclusive Interview with LongeVC's Sergey Jakimov 🌟
HasanTarek POD · Sergey Jakimov
Investing in the Age of Longevity 2022 – Sergey Jakimov – LongeVC
Master Investor · Sergey Jakimov
595th 1Mby1M Roundtable with Sergey Jakimov, LongeVC
1Mby1M Roundtables · Sergey Jakimov
Images
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