/Companies

Lygos

YC W16

San Francisco, US · Founded 2011 · Delaware corporation · 55 employees · 17 known investors

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Lygos uses genetically engineered microorganisms to produce industrial chemicals from sugar feedstocks, focusing on compounds where fermentation offers cost advantages compared to fossil fuel-based manufacturing.

Climate TechHealthtechSynthetic BiologyClimateBiotechnologyUnited States of AmericaAmerica / Canada

Founders & leadership· Y Combinator alumni (W16)

Lygos was founded in 2011 by Eric Steen and Jeffrey A. Dietrich.

ESEric Steen
Eric SteenCEO & Co-founderEric Steen is Co-Founder and Chief Scientific Officer of Lygos, a biotechnology company that engineers microorganisms to produce industrial chemicals from renewable feedstocks. He has spent over 15 years building companies across agriculture, consumer products, advanced materials, and industrial biotechnology, including helping grow Lygos from a university research spinout into a platform that raised over $210 million and built partnerships with Fortune 100 companies and U.S. government agencies.
JAJeffrey A. Dietrich
Jeffrey A. DietrichCo-founder, Chief Technology Officer2011–2019Jeffrey A. Dietrich is an executive and director at Lygos, which uses genetically engineered microorganisms to produce industrial chemicals from renewable feedstocks. He has experience in R&D leadership and corporate management across technology commercialization.
JD
Jay D. KeaslingNamed on SEC filing
JDJeffrey Dietrich
Jeffrey DietrichCo-founder, Chief Technology Officer2011–2019Founder at Rarebird

Board

LK
Leonard KatzBoard director

Investors · 17

Fifty Yearslisted by Fifty YearsSan Francisco · $250K – $2M

How we know: Fifty Years's portfolio page · the VCSheet dataset · Y Combinator's founder network · Not right? Tell us

10x GroupreportedMünchen

How we know: Y Combinator's founder network · Not right? Tell us

Agrolimen Venturesreported

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Brainchild Holdingsreported

How we know: Y Combinator's founder network · Not right? Tell us

First Round CapitalreportedSan Francisco · $100K – $20M

How we know: funding news · Y Combinator's founder network · Not right? Tell us

Four CitiesreportedNewton

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IA VenturesreportedNew York · $1M – $3M

How we know: a partner's Signal profile · funding news · Y Combinator's founder network · Not right? Tell us

OS FundreportedPark Ridge · $1M – $2M

How we know: a partner's Signal profile · the VCSheet dataset · Y Combinator's founder network · Not right? Tell us

SCM Advisorsreported

How we know: Y Combinator's founder network · Not right? Tell us

SP Investment Fundreported

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Reported raises · per SEC filings

Form D private placements

$41.7M disclosed across 4 rounds · 2016–2018

▶$10.9MraisedApr 2019 · 8 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • Eric SteenExecutive Officer, Director
  • Jay KeaslingDirector
  • Brad GillespieDirector
  • Jeffrey DietrichExecutive Officer
Offering amount
$15M
Amount sold
$10.9M
First sale
Nov 2018
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$15.5MraisedApr 2019 · 31 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • Eric SteenExecutive Officer, Director
  • Jay KeaslingDirector
  • Jeffrey DietrichExecutive Officer
  • Brad GillespieDirector
Offering amount
$20M
Amount sold
$15.5M
First sale
Mar 2018
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$14.1MraisedJul 2017 · 35 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • Eric SteenExecutive Officer, Director
  • Jeffrey DietrichExecutive Officer
  • Brad GillespieDirector
  • Jay KeaslingDirector
Offering amount
$14.1M
Amount sold
$14.1M
First sale
Oct 2016
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$1.2MraisedFeb 2016 · 13 investors · Other
Rule 506(b)
Officers, directors & promoters on the filing
  • Eric SteenExecutive Officer, Director
  • Jay D. KeaslingDirector
  • Jeffrey A. DietrichExecutive Officer, Director
  • Leonard KatzDirector
Offering amount
$2.9M
Amount sold
$1.2M
First sale
Jan 2016
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Founder mafia

2 people who came through Lygos went on to found or lead other companies.

Related companies · 5

Companies working in the same space as Lygos.

Non-dilutive funding · 11 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
Department of EnergyPhase I2018$150K
Department of Agriculture (USDA)Phase I2018$100K
National Science FoundationPhase II2015$750K
Department of Agriculture (USDA)Phase I2015$100K
Department of EnergyPhase II2014$1M
Department of Agriculture (USDA)Phase II2014$450K
National Science FoundationPhase I2014$150K
Department of Agriculture (USDA)Phase I2014$100K
Department of Agriculture (USDA)Phase I2013$100K
Department of EnergyPhase II2012$988.2K
Department of EnergyPhase I2011$150K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

Legal entities · 1

corporate structure
Lygos, Inc.

In the news

Frequently asked questions

What does Lygos do?
Lygos uses genetically engineered microorganisms to produce industrial chemicals from sugar feedstocks, focusing on compounds where fermentation offers cost advantages compared to fossil fuel-based manufacturing.
Who founded Lygos?
Lygos was founded by Eric Steen, Jeffrey A. Dietrich in 2011.
Who are Lygos's investors?
Lygos's investors include Fifty Years, FundersClub, Jude Gomila, LG Technology Ventures, Y Combinator, 10x Founders, 10x Group, Agrolimen Ventures and 9 more.
How much funding has Lygos raised?
Lygos has disclosed $41.7M raised across 4 rounds.
Where is Lygos headquartered?
Lygos is headquartered in San Francisco, US.