Fundraising FoxCentennial Investors
Angel networkColumbia · Seed
Find your way into Centennial Investors
Sign up to find every way you can get introduced to Centennial Investors
- Your email: who you already know at Centennial Investors, and who your contacts know
- 2nd- and 3rd-degree connections: people you know who worked, studied or invested with the Centennial Investors team
- Your LinkedIn: the connections who can make the intro for you
We rank every route by how warm it is, so you raise on warm intros instead of cold emails.
Investment thesis
Centennial Investors is a Columbia, Missouri angel investment group established as part of the centennial celebration of the Columbia Chamber of Commerce, working with regional partners to invest in high-growth Missouri startups.
Source: firm website, verified Oct 2, 2026.
What they invest in
from 13 of 31 portfolio companiesBiotech ×6Deep Tech ×4Hardware ×4New Materials ×4AgTech ×3Digital Health ×3Healthtech ×3Medical Devices ×3
HQs:United States×11
Who they back
founder profiles across 8 portfolio companiesFounding team size:solo founder×42 founders×34+ founders×1
Investments · 31 tracked
founders shown can be your intro pathAdSwapper operates two brands: one helps publishers and website owners monetize traffic through premium lead generation and direct advertiser connections; the other helps businesses acquire intent-focused leads in home services and auto insurance verticals.
AdTechB2B MarketplacesMarketing Tech
Amos Angelovici(Founder)in
Co-investorsMissouri Technology Corporation
Buck Surgical develops surgical technologies aimed at improving outcomes for complex procedures and expanding patient access to reconstructive and limb-preserving treatments.
HardwareHealthtechMedical DevicesSt. Louis, US
Donald W. Buck II(Founder)inDonald Buck(Executive Officer, Director)
Co-investorsMissouri Technology Corporation
CryoCrate develops cryopreservation solutions for cells and tissues in biomedical research and clinical applications, particularly for cell and tissue types that cannot be preserved or lose viability using existing storage methods.
BiotechDeep TechDigital HealthMedical DevicesNew MaterialsColumbia, US
Dr. Xu Han(President and Chief Technology Officer)
Elemental Enzymes develops peptide and biochemical solutions to protect plants from disease and stress.
AgTechBiotechCircular EconomyNew Materials
Brian Thompson(Executive Officer)
Co-investorsPaine Schwartz Partners
Healium is an immersive wellness platform that pairs VR with real-time biometric data such as EEG brainwaves and heart rate to give clinicians measurable, drug-free tools for managing patients' stress, anxiety, and pain.
Digital HealthHealthtechMental HealthWellness & Fitness
Sarah Hill(Founder)inDr. Jeff Tarrant(Co-founder)
Co-investorsCitrine AngelsKCRise FundMissouri Technology CorporationNueterra CapitalImpact Venture Capital
Immunophotonics is a clinical-stage biotech company developing novel treatments for solid-tumor cancers and infectious diseases by combining tumor ablation with systemic cancer immunotherapy.
BiotechDeep TechDigital HealthMedical DevicesSt. Louis, US
Dr. Hode(Co-Founder & Senior Fellow)Mr. Alleruzzo(Co-Founder & Director)Dr. Chen(Co-Founder)Dr. Robert Nordquist(Co-Founder)Luciano Alleruzzo(Director, Promoter)Wei Chen(Director, Promoter)
Co-investorsArgonautic VenturesBioGenerator VenturesiSelect FundMissouri Technology CorporationCultivation Capital
Impetus Ag develops early- to late-stage agricultural technologies, with a focus on Bt discovery and development and insecticidal proteins for insect and pest control in crops.
AgTechBiotechDeep TechSt. Louis, US
Jeffrey Staub(Co-founder & former Chief Scientist)inMartha Schlicher(CEO, Board of Directors)inBrian McNulty(Dr. Brian McNulty became CTO on 1/1/2021)Alexander Hromockyj(CTO)inThomas Malvar(COO)inMartha Schlicher, Ph.D., MBA(CEO, Board of Directors)
Co-investorsMissouri Technology CorporationRadicle GrowthSwan Venture FundCultivation CapitalTet Ventures
Intramotev develops battery-electric retrofit technology for rail transportation, converting traditional railcars into independently-moving, self-propelled vehicles that reduce operational costs and emissions.
Advanced ManufacturingCleantechHardwareMobility & TransportationSt. Louis, US
Timothy Luchini(Executive Officer, Director, Promoter)inAlex Peiffer(Founder)inCorey Vasel(Executive Officer, Promoter)
BoardPalmer Anna(Director)Aubrie Pagano(Director)in
Co-investorsAdvantage Capital PartnersAera VCAlpaca VCAlumni VenturesCantos VenturesCollide Capital+7 more
Kremenak NanoTech (KNT) is a deep tech startup that develops patented and patent-pending nanoengineered material platform technologies and products, including Shredder, which uses material science to prevent microbial spoilage in commercial beverage production.
Deep TechFoodTechHardwareNew MaterialsColumbia, US
Jesse Kremenak(Founder, CEO & CTO)inAJ Davis(COO)in
Co-investorsMissouri Technology Corporation
LendingStandard offers a cloud platform for commercial lenders and banks to originate, underwrite, manage, and close loans, with tools for document collection, automated credit memos, pipeline and covenant tracking, and AI-based document classification and data extraction.
AI & Machine LearningEnterprise SoftwareFintechPropTechSaaSKansas City, US
Graham Long(Head of Product)inAndrew Kallenbach(Executive Officer, Director)
BoardKeith Molzer(Director)in
Co-investorsFlyover CapitalNaples Technology VenturesSixThirty Ventures
Plastomics develops trait delivery technology for agriculture using cell biology, plant tissue culture, transformation, and molecular biology methods.
AgTechBiotechSt. Louis, US
Jeffrey Staub(Executive Officer, Director)inElizabeth Gallegos(Executive Officer)in
BoardMartha Schlicher(Executive Officer, Director)inBrian Clevinger(Director)Charles Bolten(Director)Dave Duncan(Director)
Co-investorsArgonautic VenturesBioGenerator VenturesFulcrum Global CapitaliSelect FundMissouri Technology CorporationCultivation Capital+2 more
Columbia, US
Dale Austen Prouty(Executive Officer, Director)Stephen Edward Guthrie(Executive Officer, Director)Deepak Kumar Singh(Executive Officer, Director)
Co-investorsMissouri Technology Corporation
ResistanceBio develops treatments to address drug resistance in cancer patients.
BiotechHealthtechSan Francisco, US
Nicholas Goldner(CEO/Founder)inChristopher Bulow(Founder)inKYLE LAPHAM(Executive Officer, Director)
BoardOMRI AMIRAV-DRORY(Director)in
Co-investorsAlumni VenturesFifty YearsY CombinatorAsymmetry VenturesBrightstone Venture CapitalCantos Ventures+11 more
ThermAvant Technologies designs and manufactures oscillating heat pipe (OHP) thermal management solutions and thermal straps for aero-defense and high-technology customers, including government and commercial spaceflight applications.
Defense TechHardwareNew MaterialsSpace TechUSA, US
Dr. Bill MaDr. Bin WuJoe Boswellin
Co-investorsMissouri Technology Corporation
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
BiographyBiography HealthEndevica BioEndevicabioEquinosisImpetus AgKalohexisMaxFiMaximumfidelitysurgicalsimulationsMIC Accelerator FundMissouriinnovationMobility DesignMobilitydesignedPapertrlZelusZelusenterprise
Portfolio news
latest coverage across their companiesPlastomics, Inc. · finsmes.com · Oct 28, 2025
Frequently asked questions
- How many investments has Centennial Investors made?
- Centennial Investors has 31 tracked investments.
- What stage does Centennial Investors invest at?
- Centennial Investors invests at the Seed stage.
- What sectors does Centennial Investors focus on?
- Centennial Investors focuses on Healthtech.
- Where is Centennial Investors located?
- Centennial Investors is headquartered in Columbia, US.
- Who does Centennial Investors co-invest with?
- Centennial Investors most often shares deals with Missouri Technology Corporation, Argonautic Ventures, BioGenerator Ventures, among 26 tracked co-investors.
Similar investors
83North is a global venture capital firm that invests in and helps entrepreneurs build large, category-defining companies, backing startups across multiple stages and sectors.
8VC is a venture capital firm investing across logistics, life sciences, healthcare, IT infrastructure, and government/defense, guided by its Smart Enterprise thesis focused on data integration and platform network effects.
ACT Venture Capital is an independent Irish venture capital firm that invests €1 million to €15 million in growth-stage private companies, with capacity for larger commitments through syndicated rounds.
Amadeus Capital Partners is a UK-based deep tech venture capital firm founded in 1997 that invests in technology companies from seed to growth stage. Since inception it has backed over 200 companies and raised more than $1.3 billion.
Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.