Saisei Ventures
Venture capitalCambridge · Seed–Series A · 7 people tracked
Also known as Saisei Ventures LLC
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Investment thesis
Saisei Ventures focuses on the Japanese biotech ecosystem, creating and backing ventures that translate pioneering Japanese research into globally competitive companies. It pairs cutting-edge science with global business and development experience, working alongside scientists, industry experts, and entrepreneurs. The firm targets advanced therapeutic platforms such as cell immunotherapies, pluripotent cell replacement therapies, and in vivo/ex vivo gene therapies, prioritizing programs with a realistic path to clinical and commercial-scale manufacturing and from proof-of-concept to IND. Although indication-agnostic, it concentrates on serious, life-threatening or debilitating diseases, sourcing technologies from a broad global network with a particular emphasis on Japan.
Source: firm website, verified Sep 27, 2026.
Team · 7 people
from curated & public directoriesWhat they invest in
from 3 of 6 portfolio companiesHealthtech ×3Medical Devices ×3AI & Machine Learning ×2Biotech ×2Deep Tech ×1Digital Health ×1Longevity ×1
HQs:Japan×2United States×1
Investments · 6 tracked
founders shown can be your intro pathBy year:2023 · 12021 · 12 dated
Craif develops biomarker analysis and AI-driven diagnostic solutions to enable early disease detection and personalized treatment through non-invasive testing of body fluids.
AI & Machine LearningBiotechHealthtechMedical DevicesTokyo, JP
Ryuichi Onose(Founder)inYuki Ichikawa(Director)Mika Yui(Director)Ryuichi Onose Takao Yasui(Founder)
Co-investors1955 CapitalGlobal BrainAozora Corporate InvestmentDreamers VC
CureApp HT is a smartphone application that helps patients manage hypertension through self-monitoring of blood pressure and lifestyle changes, with supporting guidance from physicians.
AI & Machine LearningDigital HealthHealthtechMedical DevicesTokyo, JP
Kohta Satake, MD, MPH, MBA(Founder)in
Co-investorsBeyond Next VenturesKeio Innovation Initiative
Tune Therapeutics develops a therapeutic platform targeting the epigenome to treat complex diseases and regenerative medicine applications.
BiotechDeep TechHealthtechLongevityMedical DevicesDurham and Seattle, US
Akira Matsuno(Co-Founder, President, CFO, COO)inDerek Jantz(Executive Officer)inCharles Gersbach(Co-Founder)inJohn McHutchison(CEO, Chairman of the Board)inDan McHugh(Co-Founder, Investor)inBlythe Sather(Executive Officer)in
Co-investorsDuke Capital PartnersHatteras Venture PartnersMission BiocapitalNew Enterprise Associates (NEA)Pappas CapitalRV Invest GmbH+2 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Kenai TherapeuticsNotch TherapeuticsUnited Immunity
Portfolio news
latest coverage across their companiesCraif · techcrunch.com · May 5, 2025
Frequently asked questions
- How many investments has Saisei Ventures made?
- Saisei Ventures has 6 tracked investments.
- What stage does Saisei Ventures invest at?
- Saisei Ventures invests at the Seed, Series A stages.
- What sectors does Saisei Ventures focus on?
- Saisei Ventures focuses on Biotech, Digital Health, Healthtech, Medical Devices, Sector Agnostic.
- Where is Saisei Ventures located?
- Saisei Ventures is headquartered in Cambridge, US.
- Who does Saisei Ventures co-invest with?
- Saisei Ventures most often shares deals with Global Brain, Hatteras Venture Partners, Mission Biocapital, among 13 tracked co-investors.
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