Invest Michigan
Venture capitalNorthville · Pre-Seed–Series A · 3 people tracked
Investment thesis
Invest Michigan, a Detroit-based Michigan nonprofit, manages the Michigan Pre-Seed Fund 2.0, a $6.8 million fund capitalized through a contract with the Michigan Strategic Fund.
Source: firm website, verified Jul 31, 2026.
Team · 3 people
from the firm's website & public directories
What they invest in
from 27 of 40 portfolio companiesBiotech ×9Healthtech ×9Hardware ×5Medical Devices ×5SaaS ×5Advanced Manufacturing ×4AI & Machine Learning ×4Digital Health ×4
HQs:United States×20
Investments · 40 tracked
founders shown can be your intro pathBy year:2025 · 12024 · 12023 · 12020 · 12019 · 12015 · 16 dated
Shoulder Innovations develops InSet® glenoid technology for shoulder joint implants that reduce the rocking horse effect and provide mechanical stability, serving patients with severe shoulder arthritis.
HardwareHealthtechMedical DevicesNorthern California, US
Robert Ball(CEO & Executive Chairman)Matthew Ahearn(Chief Operating Officer)Jeff Points(Executive Officer)David Blue(Executive Officer)Don Running(Manager and Chief Executive Officer)Jeff Ondrla(Chief Technology Officer)
ONL Therapeutics is a clinical-stage biopharmaceutical company developing neuroprotective treatments for retinal diseases including retinal detachment, geographic atrophy, and glaucoma.
BiotechHealthtechMedical DevicesAnn Arbor, US
David Zacks(Executive Officer)David Esposito(Executive Officer, Director)Constance Chang(Executive Officer)Loic Couraud(Director)William Brinkerhoff(Director)Mark Hooper(Director)
AdAdapted builds a platform that connects digital advertising to purchase intent for consumer packaged goods brands and agencies, enabling shoppers to see relevant ads earlier in their buying journey.
AdTechConsumerMarketing TechAnn Arbor, US
Molly McFarland(Executive Officer)Michael Pedersen(Executive Officer, Director)Robert Cell(Director, Promoter)
Akadeum manufactures GMP-compliant ancillary materials for cell and gene therapy applications, specializing in microbubble-based negative selection products.
Advanced ManufacturingBiotechDeep TechHealthtechMedical DevicesAnn Arbor, US
James Militello(Executive Officer)Kalyan Handique(Executive Officer, Director)Douglas Neal(Director)John Younger(Executive Officer, Director)
BoardJeffrey S. Williams(Director)Paul D'Amato(Director)
Wyoming, US
Mark Groendal(Executive Officer, Director)Daniel Molhoek(Director)
Autobooks provides embedded banking technology to financial institutions to help them attract and retain small business customers by enabling business owners to manage finances and cash flow directly through their bank's digital platform.
Enterprise SoftwareFintechSaaSDetroit, US
Steven Robert(Executive Officer)John Schmid(Executive Officer)Jeff Blackman(Executive Officer)in
HealthtechAnn Arbor, US
RONALD FRISBIE(Executive Officer)WILLIAM CLARKE(Director)HANNAH HENSEL(Executive Officer, Director)
Climate TechAnn Arbor, US
EVOQ Therapeutics develops immunotherapies for autoimmune diseases using its proprietary NanoDisc technology, which delivers disease-specific antigens to dendritic cells via subcutaneous administration to restore native immune tolerance.
BiotechHealthtech
Fusion Coolant Systems develops Pure-Cut, a supercritical CO2-based cooling and lubrication system for CNC machine tools that replaces traditional cutting fluids.
Advanced ManufacturingCleantechNew Materials
Genomenon uses purpose-built AI combined with expert scientific curation to index and structure real-world evidence from millions of biomedical articles, including full text, tables, figures, and supplemental data.
AI & Machine LearningBiotechDigital HealthAnn Arbor, US
Eli Salembier(Executive Officer, Director)Mark Kiel(Executive Officer, Director)Sonya Sepahban(Director)Michael Klein(Executive Officer, Director)Patricia Glaza(Director)David Gregorka(Director)
BiotechEast Lansing, US
Steven Bloembergen, PhD(Executive Officer, Director)Steven Bloembergen(Executive Officer, Director)Kenneth Pienta(Director)Frank van Luttikhuizen(Director)
BoardMichael Snyder(Director)Joerg Lahann, Ph.D.(Director)
High Yield Savings by Plinqit is a white-labeled, end-to-end savings product that helps banks and credit unions attract deposits, launch digital savings brands, and expand into new markets, handling KYC and compliance.
FintechSaaS
Kathleen Craig(Founder & CEO)in
Owner of ADHD Online; provides mental health diagnosis and treatment via smart assessments.
Grand Rapids, US
Randall Duthler(Director)Keith Brophy(Executive Officer)Dave Peralta(Executive Officer)Zachariah Booker(Director)Kristine White(Director)Barry Herman(Executive Officer)
Portage, US
John Balbach(Director)Tim Parker(Director)Deepak Ravindra(Executive Officer, Director)John Jackoboice(Director)
AgTechKalamazoo, US
Lee Huey(Director)Brian Steensma(Director)James Friedrich(Executive Officer, Director)Larry Mayberry(Director)
BoardSteve Haakenson(Director)
Orbion manufactures Hall-effect electric propulsion systems for small satellites, enabling orbital maneuvers, lifetime extension, and cost reduction.
Deep TechHardwareSpace Tech
Orthoforge develops ultrasonic medical devices that quantify the stage of bone fracture and soft tissue healing without radiation, providing objective feedback to healthcare professionals.
Digital HealthHardwareMedical Devices
The page presents open source tools, pretrained models, APIs, SDKs, and GPU-accelerated pipelines for healthcare and life sciences developers, covering drug discovery, healthcare robotics, medical imaging, genomics, and digital health.
AI & Machine LearningBiotechHealthtech
Advanced ManufacturingAnn Arbor, US
Lihang Nong(Executive Officer, Director)
Ripple Science offers EnrollNow, a HIPAA-compliant and SOC 2-certified platform for managing research participant prescreening, enrollment, scheduling, engagement, and study tracking.
Digital HealthHealthtechSaaS
SafeSense Technologies designs and manufactures flexible hybrid electronics, working with customers to develop, design, test, and produce custom electronics solutions.
Advanced ManufacturingDeep TechHardware
Ann Arbor, US
Robert Cell(Director)Laura Khoury(CEO and President)Nancy Gilby(Director)
SkySpecs provides data management and analytics software for renewable energy asset operators, helping them optimize maintenance and operational decisions for wind and solar installations.
AI & Machine LearningCleantechClimate TechEnergySaaSAnn Arbor, US
David Roberts(CEO)Daniel Ellis(President and CEO)Thomas Brady(CFO)James Adox(Director)
BoardRichard Katz(Director)Peter Wells(Director)
SpellBound develops mobile augmented reality applications for healthcare settings to engage and educate patients throughout their care journey, including distraction tools for waiting rooms and at-home engagement solutions.
Digital HealthHealthtech
BiotechAnn Arbor, US
JONATHAN LEINONEN(Executive Officer, Director)YOKE KHIN YAP(Executive Officer, Director)MICHAEL MORTLOCK(Executive Officer)MARK EHLERT(Director)STEVE TOKARZ(Executive Officer, Director)JOHN RANSOM(Director)
Tetra Therapeutics (Tetra Discovery Partners) was a discovery-based pharmaceutical company developing clinical programs including treatments for Fragile X Syndrome.
BiotechHealthtechFlorham Park, US
Exits · 1
IPOs and acquisitions across the tracked portfolioShoulder InnovationsNYSE: SI
Portfolio news
latest coverage across their companiesShoulder Innovations · investing.com · Jun 29, 2026
Akadeum Life Sciences · finsmes.com · Jun 4, 2025
Autobooks · saastake.com · May 13, 2025
SkySpecs · annarborusa.org · Mar 20, 2025
Frequently asked questions
- What stage does Invest Michigan invest at?
- Invest Michigan invests at the Pre-Seed, Seed, Series A stages.
- What is Invest Michigan's typical check size?
- Invest Michigan typically writes checks of $100K – $250K.
- What sectors does Invest Michigan focus on?
- Invest Michigan focuses on Advanced Manufacturing, Biotech, Defense Tech, Energy, Enterprise Software, Healthtech, Medical Devices, New Materials, SaaS.
- Where is Invest Michigan located?
- Invest Michigan is headquartered in Northville, US.
Images
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