Catalio Capital Management, LP — Full Portfolio

Avalyn Pharma develops inhaled therapies for pulmonary fibrosis, using a nebulization approach that delivers treatment directly to the lungs to reduce the tolerability problems of existing oral therapies.

BiotechHealthtech

LBLyn Baranowski(CEO)in

Co-investorsANAndera PartnersF-F-Prime CapitalINInVivium CapitalNONorwest Venture PartnersPIPivotal Life SciencesRIRiverVest Venture Partners+9 more

Compass Pathways develops novel treatments for mental health conditions, with a focus on psychedelic-assisted therapies supported by rigorous clinical research.

BiotechDigital HealthHealthtechMedical DevicesMental Health

Kabir Nath(CEO)Ekaterina Malievskaia(Founder)George Goldsmith(Founder)

Co-investorsABAble PartnersAIAisling CapitalBABailey Venture PartnersNONoeticOMOMX VenturesVIVivo Capital+2 more

Fractyl develops therapies for obesity and type 2 diabetes, focusing on non-drug-based approaches rooted in understanding metabolic disease mechanisms.

BiotechHealthtechMedical DevicesLexington, US

Jay Caplan(Founder)inHRHarith Rajagopalan(Co-Founder and CEO)inLDLISA DAVIDSON(Executive Officer)inDiane Marcou(Executive Officer)in

BoardAWAllan Will(Director)inNSNimesh Shah(Director)in

Co-investorsBEBessemer Venture PartnersEMEmergent Medical Partners, LLPGEGeneral CatalystMIMithril Capital ManagementDODomain AssociatesPOPolaris Partners+1 more

Freenome develops early-stage cancer detection technology using blood tests to identify cancer in its earliest, most treatable phases.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesLondon, US

RERiley Ennis(Founder)inCharles Roberts(Founder)inGOGabriel Otte(Founder)inAdam Stone(Chief Executive Officer and Director)Michael Altman(Chief Business Officer and Director)Shmuel (Sam) M. Cohn(Chief Financial Officer)

Co-investorsRARA CapitalAGAgent CapitalAMAME Cloud VenturesANAndreessen HorowitzARArtis VenturesASAsset Management Company+15 more

Kardigan develops targeted cardiovascular treatments through a discovery and translational research platform, with a pipeline of late-stage drug candidates aimed at functional cures for cardiovascular disease.

AI & Machine LearningBiotechHealthtechMedical Devices

Co-investorsARARCH Venture PartnersSESequoia CapitalSESequoia HeritageT.T. Rowe PriceVEVenrock

Neumora is a clinical research company developing investigational medications, with a focus on conducting clinical trials to obtain regulatory approval and make treatments available to patients.

BiotechDeep TechDigital HealthMedical DevicesWatertown, US

PLPaul L. Berns(Chairman and Chief Executive Officer)Joshua Pinto(Executive Officer)TTTamara Tompkins(Executive Officer)inKari Stefansson(Director)MHMaykin Ho(Director)AHAlaa Halawa(Director)

Co-investorsARARCH Venture PartnersF-F-Prime CapitalK2K2 HealthVenturesMEMercury FundPRPremier PartnersSOSoftBank Vision Fund+12 more

Helicons develops a peptide-based therapeutic platform designed to target intracellular proteins previously considered undruggable by combining the specificity of antibodies with the cell-penetrating properties of small molecules.

AI & Machine LearningBiotechDeep TechMedical Devices

MMMathai Mammen(CEO, President and Chairman)in

Co-investorsARARCH Venture PartnersFOForesite CapitalFRFrazier Life SciencesGEGeneral CatalystGVGV (Google Ventures)HBHBM Healthcare Investments+9 more

Protara develops transformative therapies for patients with cancer and rare diseases, applying modern scientific and manufacturing advancements to accelerate drug development.

BiotechHealthtechMedical Devices

JSJesse Shefferman(President, Chief Executive Officer and Director)inPFPatrick Fabbio(Chief Financial Officer)inJacqueline Zummo(Chief Research & Development Officer)inWilliam Conkling(Chief Commercial Officer)LNLeonardo Nicacio(Chief Medical Officer)

Recursion applies computational and data-driven approaches to biological science, aiming to accelerate drug discovery and develop new treatments.

AI & Machine LearningBiotechData & InfrastructureDeep TechMedical DevicesSalt Lake City, US

CGChris Gibson(Co-founder and Chairman of the Board)inBCBlake C. Borgeson(Executive Officer, Director)inDean Y. Yi(Executive Officer, Director)NKNajat Khan(Chief Executive Officer)inNajat Khan, Ph.D.(CEO and President)inBlake Borgeson(Founder)

Co-investorsDCDCVC (Data Collective)LULux CapitalBABaillie GiffordADAdvantage Capital PartnersAIAir Street CapitalAMAmplify Partners+22 more

9amHealth provides virtual care for cardiometabolic conditions, offering weight management, diabetes care, and heart health treatment that combines prescription medication (including GLP-1s), lifestyle coaching, and lab testing.

Digital HealthHealthtechWellness & FitnessEncinitas, US

FWFrank Westermann(Executive Officer, Director)inAKAnton Kittelberger(Founder)inMHMichael Hofner(Executive Officer)inAWAvantika Waring(Executive Officer)PGPaul Geevarghese(Executive Officer)inBSBernhard Schandl(Executive Officer)in

Co-investors7W7wire VenturesCACalm/Storm VCDEDefine VenturesHAHabitat PartnersHAHansmann Family OfficeLILIP Ventures Boutique+4 more

Abridge builds AI software that converts clinical conversations into structured insights for healthcare providers.

AI & Machine LearningDigital HealthHealthtechPhiladelphia, US

SRShiv Rao(CEO, Co-Founder)inSKSandeep Konam(Founder)inJCJulia Chapin(Founder)Sagar Sanghvi(Executive Officer)inFlorian Metze(Founder)Shivdev Rao(Founder)

Co-investorsALAlpha Square GroupALalphabet angelsANAndreessen HorowitzATAtria VenturesBEBessemer Venture PartnersCACapitalG+27 more

AdvanCell is a clinical-stage radiopharmaceutical company developing a pipeline of targeted alpha therapies for the treatment of cancers including prostate, melanoma, ovarian, breast, and lung.

BiotechHealthtechMedical DevicesCambridge, US

AAAndrew Adamovich(Director)inPLPhilina Lee(Executive Officer, Director)inAPAaron Pickett(Executive Officer)in

BoardWing Cheong Lam(Director)Nik Economopoulos(Director)Anthony Aiudi(Director)

Co-investorsBABain Capital Life SciencesPRProto AxiomSASanofi VenturesSVSV Health InvestorsTETenmileABAbingworth+2 more

Alentis is a biotech company developing therapies for chronic liver disease, fibrosis, and cancer based on the molecular biology of liver disease.

AI & Machine LearningBiotechHealthtechMedical DevicesBasel, CH

TBThomas Baumert(Founder)inMPMark Pruzanski(Chief Executive Officer)inLMLuigi Manenti(Chief Medical Officer)inJFJon Freve(Chief Financial Officer)inBYBryan Yoon(General Counsel and Chief Administrative Officer)inAVAditya Venugopal(Chief Business Officer)in

Co-investorsAVAvego BioScience CapitalBIBioMedPartnersFRFrazier Life SciencesJEJeito CapitalLOLongitude CapitalNONovo Holdings+5 more

Amalgam builds a modular, AI-powered Software as a Medical Device (SaMD) platform and EHR-integrated solutions for life sciences companies, health plans, and providers to support clinical decisions, patient engagement, and digital therapeutics.

AI & Machine LearningDigital HealthHealthtechWilmington, US

RSRyan Sysko(Founder)in

BoardSONNY VU(Director)JEFFREY P. COURTNEY(Director)

Co-investorsCVCVS Health VenturesSUSupermorpheus

ArriVent BioPharma is a clinical-stage biopharmaceutical company focused on identifying, developing, and commercializing medicines for difficult-to-treat diseases, starting with cancers.

BiotechHealthtechMedical DevicesNewtown Square, US

Z(Zhengbin (Bing) Yao(Executive Officer, Director)inBRBrent Rice(Chief Commercial Officer)in

BoardJason Zhang(Director)Cong Xu(Director)Stuart Lutzker(Director)

Co-investorsFOForesite CapitalGEGeneral CatalystHBHBM Healthcare InvestmentsHBHBM PartnersHOHongShan Capital GroupLALAV+4 more

New York-based D2C provider of high-quality hearing aids in the US.

HealthtechNew York, US

PFPatrick Freuler(Executive Officer, Director)inAndre Sequin(Executive Officer)

Co-investorsECECONA AGHOHOWZAT PartnersNANat TurnerTITIA Ventures

Biotechnology company developing immunomodulators using a HALOS nanotechnology platform for chronic inflammation.

BiotechDigital HealthHealthtechMedical DevicesCambridge, US

MTMichael Tolentino(Executive Officer, Director)inMAMohamed A. Genead(Chairman & CEO)inDavid Callanan(Executive Officer)inDerek Kunimoto(Executive Officer)inJNJeffrey Nau(Chief Executive Officer)inTSTarek S. Hassan(Chief Development Officer)in

Co-investorsJEJeito CapitalLOLongitude CapitalOROrbiMedAVAvoro Capital AdvisorsDIDigitalis VenturesOMOmega Funds

Axena Health develops digital therapeutic devices for women's pelvic health, specifically treating urinary and fecal incontinence through at-home pelvic floor muscle training.

Digital HealthFemTechHealthtechMedical DevicesAuburndale, US

SPSamantha Pulliam(CEO and Chief Medical Officer)inVRVincent Ricci(Executive Officer)JOJim O'Connor(Executive Officer)inSPShacey Petrovic(Executive Officer, Director)inEileen Maus(Executive Officer, Director)in

BoardJonathan Dean(Director)

Co-investorsAVAvestria VenturesCRCross-Border Impact VenturesSOSolas BioVentures

Bayesian Health develops clinical artificial intelligence for real-time patient monitoring and clinical decision support.

AI & Machine LearningDigital HealthHealthtechMedical Devices

SSSuchi Saria(Founder and CEO)in

Co-investorsANAndreessen HorowitzEPEpsilon Health InvestorsHEHealth2047 Capital Partners LLCLILifeforce CapitalMEMemorialCare Innovation Fund

Beacon Biosignals develops AI-powered EEG analytics technology to improve diagnosis and treatment of neurological, psychiatric, and sleep disorders.

AI & Machine LearningBiotechDigital HealthMedical DevicesBoston, US

Jacob A. Donoghue, M.D., Ph.D.(Executive Officer, Director)JDJacob Donoghue(CEO & Co-Founder)inJRJarrett Revels(CTO & Co-Founder)in

BoardCaitlin Donovan(Director)Pavel Raifeld(Director)NRNaveen Rao(Director)in

Co-investorsGEGeneral CatalystALAlumni VenturesGVGV (Google Ventures)IAIaso VenturesIRIrregular ExpressionsKIKicker Ventures+4 more

Blackrock Neurotech develops a neurotechnology platform, including brain-computer interface systems, aimed at improving patient lives and treating neurological conditions.

BiotechDeep TechMedical Devices

FSFlorian Solzbacher(Co-Founder & CSO)inMGMarcus Gerhardt(Co-Founder & CEO)inTTThomas Thiele(CFO)in

BoardChristian Angermayer(Co-Chairman)Tim Sievers(Co-Chairman)

Co-investors202050 CapitalFOForepont Capital PartnersPRPresight CapitalWPWPSS InvestmentsTETether

Cambrian Bio is a clinical-stage drug development company creating precision therapeutics that target metabolic pathways which decline with age, such as AMPK and mTOR.

BiotechHealthtechLongevityNew York, US

JPJames Peyer(CEO, Founder, Board Director)inMNMark Nuttall(Chief Business Officer)inRTRuth Thieroff-Ekerdt(Chief Medical Officer)inBDBill DeVaul(Chief Legal Officer)in

BoardCAChristian Angermayer(Chairman, Co-Founder, Board Director)inMSMaryanna Saenko(Director)in

Co-investorsALAlumni VenturesFJFJ LabsFUFuture VenturesKHKhosla VenturesKOKorify CapitalSPSprint Vc+4 more

Carbon Health operates a chain of clinics offering urgent care, primary care, and chronic condition management, combining technology with in-person care to provide broader access to health services.

Digital HealthHealthtechMedia & Entertainment

EBEren Bali(Founder)inGBGreg Burrell(Founder)inTom Berry(Founder)Caesar Djavaherian(Founder)Greg Burell(Founder)

Co-investors50500 Emerging Europe50500 Global51515 VenturesAKAkkadian VenturesANAnnex InvestmentsBUBuilders VC+31 more

Cartography develops antibody-based cancer therapies using single-cell sequencing and computational biology to identify precise cellular targets.

AI & Machine LearningBiotechDeep TechMedical DevicesSouth San Francisco, US

MMMax Mumbach(Founding Scientist, Target Discovery)inJVJeffrey Verboon(Founding Scientist, Computational Biology)inASAnsu Satpathy(Founder)KPKevin Parker, PhD(Chief Executive Officer, Board Director; co-founder)ASAnsuman Satpathy, MD, PhD(Co-founder; Board Director)HCHoward Chang(Founder)in

Co-investors8V8VCANAndreessen HorowitzARArtis VenturesFIFinchley Healthcare VenturesGAGaingelsGLGlobal BioAccess Fund+9 more

Combines single-cell RNA analysis technology from the Broad Institute with AI/ML models and large-scale clinical sample collection for novel drug discovery and precision medicine.

HealthtechCambridge, US

TKTariq Kassum(Executive Officer, Director)inMBMichael Boretti(Executive Officer)inCLChristoph Lengauer(Executive Officer, Director)in

Co-investorsFAFast Track InitiativeGVGV (Google Ventures)ALAlexandriaAMAmplitude Venture CapitalCACasdin CapitalTHThird Rock Ventures

Centenara Labs is a longevity-focused drug discovery company that translates research on the biology of aging into therapies intended to improve healthy aging and extend lifespan.

BiotechHealthtechLongevity

CAChristian Angermayer(Founder)in

Co-investorsGAGaingelsKOKorify CapitalMAManta International Consultancy S.A.LP5P53 Invest

Centrexion develops therapies for the treatment of pain, focusing on the design and execution of clinical trials for pain drug development.

BiotechHealthtechBaltimore, US

JNJames N. Campbell(President, Chief Scientific Officer)inKLKerrie L. Brady(Executive Officer)inGregg Beloff(Executive Officer)JBJeffrey B. Kindler(Chief Executive Officer)inCOCharles Oh(Chief Medical Officer)inSSSmital Shah(Acting CBO)in

Co-investorsEFEFung CapitalNENew Enterprise Associates (NEA)QUQuan Capital6 6 Dimensions CapitalAVAvoro Capital AdvisorsEXExome Asset Management

Character Bio is a patient-driven therapeutics company that combines genomics, longitudinal clinical and imaging data, and machine learning to identify genetic drivers of disease progression and develop new treatments, with a focus on polygenic diseases.

AI & Machine LearningBiotechDigital HealthJersey City, US

CZCheng Zhang(CEO, Co-Founder)inMarcel van der Brug(Scientific Advisor, Co-Founder)inNick Johnson(Technology Advisor, Co-Founder)inDEDaniel Elgort(Chief Data and Analytics Officer)inLCLaura Carter(Chief Scientific Officer)inRobert Kim(Chief Medical Officer)in

Co-investorsAMaMoonLULuma GroupSASanofi VenturesINInnovation EndeavorsCACantos VenturesDUDuke Capital Partners+5 more

Claris Bio develops biologic therapies for sight-threatening eye diseases, with a current focus on bringing CSB-001, a novel treatment for patients with limbal stem cell deficiency, through clinical development and to market.

BiotechHealthtechMedical DevicesJersey City, US

CAClarke Atwell(Co-Founder and Chief Operating Officer)inHenry Rath(Executive Officer)SOSusan Orr(Executive Officer)inStephen Brady(Executive Officer, Director)Michael Dybbs(Director)Matt Hobson(Director)

Co-investorsRARA CapitalSOSofinnova VenturesCACatalio Capital ManagementNONovo HoldingsSASamsara BioCapital

Clasp Therapeutics develops off-the-shelf precision T cell engagers (its proprietary pHLАre molecules) that target mutant peptide-HLA complexes displayed on cancer cells, directing T cells to destroy tumors carrying common driver mutations such as KRas.

BiotechHealthtechCambridge, US

Co-investorsCUCure VenturesVIVivo CapitalBRBrightEdgeCACatalio Capital ManagementNONovo HoldingsTHThird Rock Ventures

Cresilon develops plant-based flowable hemostatic gel technology that controls bleeding within seconds without manual pressure, with products for veterinary care (VETIGEL) and human trauma (TRAUMAGEL).

BiotechHealthtechMedical DevicesNew MaterialsBrooklyn, US

IMIsaac Miller(Co-founder)inJLJoe Landolina(Co-founder & CEO)inSLScott Levine(Executive Officer)in

Co-investorsDODorm RoomINInnovating Capital

DNA Script develops enzymatic DNA synthesis technology, producing nucleic acids for research and biotech applications.

BiotechDeep TechHardwareParis, FR

TYThomas Ybert(Founder)inXGXavier Godronin

Co-investorsCOCoatue ManagementILIllumina VenturesKUKurma PartnersM M VenturesSOSofinnova PartnersCACasdin Capital

Biotechnology company using multiplex gene editing to develop genetically engineered porcine organs for human transplantation.

BiotechBrookline, US

Luhan Yang(President, Secretary and Treasurer)Geoff MacKay(Chief Executive Officer)

BoardGMGeorge M. Church(Director)

Co-investorsALAlta PartnersARARCH Venture PartnersHBHBM Healthcare InvestmentsHBHBM PartnersKHKhosla VenturesLILifeSci Venture Partners+12 more

Elektrofi is a biotech company developing an ultra-high concentration microparticle formulation platform that enables subcutaneous delivery of biologic medicines such as monoclonal antibodies.

BiotechDeep TechHealthtechMedical DevicesBoston, US

Chase Coffman(Chief Executive Officer & Co-founder)inSam Huang(Director)Jason Norris(Co-founder)Charles L. Cooney(Director)Andrew Goldberg(Director)Constatine Chinoporos(Director)

Co-investorsBIBiotechnology Value FundNONovo HoldingsCHCharlotte Angel FundGEGeneral CatalystRARA CapitalSRSR One Capital Management+1 more

Ensoma is a genomic medicine company developing a platform for in vivo engineering of hematopoietic stem cells (HSCs), combining an off-the-shelf delivery system with a gene engineering toolkit intended to treat diseases with a one-time treatment.

BiotechHealthtechMedical DevicesBoston, US

Albert Seymour(Director)

BoardKPKush Parmar(Executive Officer, Director)inPSPaula Soteropoulos(Director)SKStephen Knight(Director)in

Co-investors5A5AM VenturesAJAju IB InvestmentDEDelos CapitalF-F-Prime CapitalSOSolasta VenturesVIViking Global+10 more

Enveda operates a drug-discovery platform that analyzes natural samples—primarily plant-derived molecules—using mass spectrometry, AI foundation models, and automated high-throughput labs to identify their chemical structures and therapeutic properties.

AI & Machine LearningBiotechDeep TechBoulder, US

VCViswa Colluru(Founder)inDaniel Wee(Executive Officer)Pieter Dorrestein(Founder)Viswa Colluru Pieter Dorrestein(Founder)

BoardRohit Sharma(Director)ZDZavain Dar(Director)in

Co-investorsAIAir Street CapitalBOBoulder VenturesCOCox EnterprisesFPFPVGAGaingelsHUHummingbird Ventures+21 more

Erisyon is a biotechnology company that develops technology to advance scientific and health discoveries, building on research from the University of Texas at Austin's Center for Systems and Synthetic Biology.

BiotechDeep TechHealthtech

Co-investorsFOFoothill Ventures

FogPharma develops ultra-tunable Helicon peptide therapeutics designed to reach historically undruggable targets, aiming to treat cancer and other serious diseases.

BiotechBoston, US

Gregory L Verdine(Executive Officer, Director)MMMathai Mammen(CEO, President and Chairman)in

Co-investorsHOHorizons VenturesGVGV (Google Ventures)VEvenBio Global Strategic

Georgiamune is a biopharmaceutical company developing targeted immunomodulator drugs that activate or down-modulate immune signaling pathways to treat cancer and autoimmune diseases.

BiotechDeep TechHealthtechGaithersburg, US

SNSamir N. Khleif(Founder & CEO)inRIRamy Ibrahim(Chief Medical and Strategy Officer)inMMMikayel Mkrichyan(Senior Vice President of Science and Discovery)SSSarah Sharman(Vice President of IP Legal Affairs)

BoardSPSean Parker(Director)EVElena Viboch(Director)in

Co-investorsGEGeneral CatalystHAHAWKTAILLALauder PartnersPRPrevail Venture CapitalALAlexandriaCACatalio Capital Management+3 more

GlycoEra develops glycan-based therapeutics, applying glycoengineering technology to create biologic drugs.

BiotechHealthtechNewton, US

Ganesh V. Kaundinya(President & CEO)in

Co-investors5A5AM VenturesLILifeArc VenturesRORoche Venture FundSISixty Degree CapitalSOSofinnova PartnersAGAgent Capital+1 more

Hippocratic AI develops generative AI agents designed for healthcare delivery, working with hospital systems, health plans, and life sciences companies to support clinical decision-making and patient care.

AI & Machine LearningDigital HealthHealthtech

MSMunjal Shah(Chief Executive Officer, Co-founder)inDMDr. Meenesh Bhimani(Chief Medical Officer, co-founder)inVPVishal Parikh(Chief Product Officer, Co-founder)inSMSubho Mukherjee(Chief Science Officer, Co-founder)inSGSaad Godil(Founder)inS(Subhabrata (Subho) Mukherjee(Founder)in

Co-investorsANAndreessen HorowitzGEGeneral CatalystA*A*AVAvenir Growth CapitalFOFounders Circle CapitalGRGreycroft+7 more

Iambic develops AI technologies for drug discovery, using a high-throughput experimental platform to design small-molecule medicines and advance a pipeline of clinical candidates for cancers such as HER2-driven, breast, and ovarian tumors.

AI & Machine LearningBiotechDeep TechSan Diego, US

TMTom Miller(Founder)inFred Manby(Founder)inCZChao Zhang(Executive Officer)inTabbert Teng(Executive Officer)NJNeil Josephson(Chief Medical Officer)inPOPete Olson(Chief Scientific Officer)in

Co-investorsASAscenta CapitalABAbingworthCACatalio Capital ManagementALAlumni VenturesCOCoatue ManagementEIEisai Innovation, Inc.+7 more

Imbria Pharmaceuticals develops novel cardiovascular disease treatments that target cardiac energy metabolism, with a lead drug candidate, ninerafaxstat, in clinical trials for non-obstructive hypertrophic cardiomyopathy.

BiotechDigital Health

ASAlvin Shih(CEO)inAMAlbert M. Kim(Chief Medical Officer)in

Co-investorsANAN Venture PartnersRARA CapitalSASanofi VenturesSVSV Health InvestorsCACatalio Capital Management

Immunai develops AMICA, a data platform for decoding the immune system to accelerate drug discovery and development.

AI & Machine LearningBiotechData & InfrastructureNew York City, US

Luis Voloch(Founder)Noam Solomon(Founder)

Co-investorsGEGefen CapitalKOKoch Disruptive TechnologiesMEMeron CapitalPEPerot JainTLTLV PartnersVIViola Ventures+2 more

Imperative Care develops medical technologies for treating stroke and other vascular diseases, aiming to address gaps across the patient care journey.

HealthtechMedical DevicesCampbell, US

Farhad Khosravi(Executive Officer, Director)MGMatthew Garrett(Executive Officer)inCharles Alpuche(Executive Officer)SEScott Elliott(Executive Officer)in

BoardJames Rogers(Director)SEStacy Enxing Seng(Director)

Co-investorsASAscension VenturesBABain Capital Life SciencesDEDelos CapitalFEFemHealth VenturesLILightstone Ventures

Insightec develops Exablate Neuro, an MRI-guided focused ultrasound platform that treats Essential Tremor and tremor-dominant Parkinson's Disease through an incision-free outpatient procedure.

HealthtechMedical DevicesTirat Carmel

Roni Karie(Vice President - Finance)SAShirel Aroshase(Vice President - Human Resources)inEZEyal Zadicario(General Manager)inMenashe Frank(Vice President - Legal)inJ(Jun (Jim) Tao(Chief Operating Officer)inMRMaurice R. Ferre(Chairman and Chief Executive Officer)in

Co-investorsEXExigent CapitalGEGEOCJAJazzya InvestmentsKOKoch Disruptive TechnologiesKRKrillion VenturesPEPeregrine Ventures+6 more

Kailera develops obesity management medications, including GLP-1 and multi-agonist receptor peptides and small molecules, with a global development pipeline led by injectable and oral formulations of ribupatide.

BiotechHealthtechMedical Devices

Co-investorsATAtlas VentureBABain Capital Life Sciences

Lassen Therapeutics is a biotechnology company developing therapeutics targeting IL-11, with a pipeline focused on immune and fibrotic diseases.

Biotech

DKDavid King(Co-Founder & CSO)inMFMaria Fardis(CEO)inCCCadmus C. Rich(Chief Medical Officer)inESElaine Stracker(General Counsel)in

Co-investorsALAlta PartnersDCDC Investment PartnersFRFrazier Life SciencesLOLongitude CapitalLOLongwood FundBIBiotechnology Value Fund+2 more

Leo Cancer Care develops upright radiotherapy and particle therapy solutions that integrate CT imaging with patient positioning systems.

Deep TechHardwareHealthtechMedical Devices

STStephen Towe(Founder)in

Co-investorsDEDevice of Tomorrow CapitalGAGaingelsSESerra VenturesSTStar51 CapitalYUYu GalaxyCACatalio Capital Management+1 more

LifeSprout develops synthetic materials that mimic the body's own tissues for aesthetic and regenerative medicine, creating products to treat patients with soft tissue loss from aging, cancer, and metabolic disease.

BiotechMedical DevicesNew MaterialsBaltimore, US

HMHai-Quan Mao(Co-founder, PhD)SRSashank Reddy(Co-founder, MD, PhD)KCKevin Colbert(Co-founder, Business Development)inRMRuss Martin(Co-founder, Head of R&D, PhD)inAGAdam Gridley(Executive Chairman, MBA)

Co-investorsEMEmerald Development ManagersMAMaryland TEDCOTETEDCO

LILA Sciences builds AI systems for autonomous scientific research and discovery across medicine, materials, energy, and defense sectors.

AI & Machine LearningBiotechDeep TechSaaS

Geoffrey von Maltzahn(CEO)Molly Gibson(Founder)Noubar Afeyan(Founder)

Co-investorsALAlumni VenturesDADauntless VenturesFLFlagship PioneeringGEGeneral CatalystINIn-Q-TelMAMarch Capital Partners+9 more

Metagenomi is a genetic medicines company developing therapies based on gene editing technologies to treat patients with serious diseases.

BiotechDeep TechHealthtechMedical DevicesBerkeley, US

BTBrian Thomas(Founder)inBrian Thomas Jillian Banfield(Founder)Jill Banfield(Founder)Jian Irish(President and CEO)

BoardAFAndrew Farquharson(Director)inJak Knowles(Director)

Co-investorsRARA CapitalSOSozo VenturesAGAgent CapitalFRFrazier Life SciencesHUHumboldtINInCube Ventures+5 more

NextPoint is a precision therapeutics company developing cancer treatments targeting the B7-H7/HHLA2 axis, including a T-cell engager, an antibody-drug conjugate with proprietary linker technology, and a multi-functional checkpoint inhibitor.

BiotechHealthtechAustin, US

GFGordon Freeman(Scientific Founder)XZXingXing Zang(Scientific Founder)inICIvan Cheung(Chief Executive Officer)inLGLeena Gandhi(Chief Medical Officer)inTNTatiana Novobrantseva(Chief Scientific Officer)inAHAxel Hoos(Director)

Co-investorsMPMPM BioImpactSASanofi VenturesCACatalio Capital ManagementINInvusLELeaps by BayerSISixty Degree Capital

Noetik builds AI models to identify cancer patients most likely to respond to treatments and to discover new oncology drug targets.

AI & Machine LearningBiotechHealthtechSouth San Francisco, US

Jacob Rinaldi(Founder)inRonald Alfa(Executive Officer, Director, Promoter)RARon Alfa, MD, PhD(Co-Founder, CEO)inRon Alfa(Founder)Ron Alfa Jacob Rinaldi(Founder)

BoardJHJames Hardiman(Director)in

Co-investors1111.2 CapitalBRBreakout LabsBRBreakout VenturesEPEPIC VENTURESINIntermountain HealthLILinearis Ventures+6 more

Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases.

AI & Machine LearningBiotechDeep TechMedical DevicesEmeryville, US

SKSri Kosuri(Founder)inRHRamsey Homsany(Founder)inRobert Andrade(Executive Officer, Director, Promoter)Maurice J. Costantini(Executive Officer, Director, Promoter)

Co-investorsANAndreessen Horowitz+N+ND Capital8V8VCCACarbon SiliconEXExplorer InvestmentsFIFifty Years+10 more

Odyssey Therapeutics develops small molecule and protein therapeutics targeting upstream signaling nodes and innate immune system mechanisms to prevent pathological inflammation.

BiotechMedical DevicesCambridge, US

GDGary D Glick(Executive Officer, Director)inGary D. Glick(Founder)Gary D. Glick, Ph.D.(Founder, President & CEO)

BoardJCJill Carroll(Director)inCGCarl Gordon(Director)inValerie Odegard(Director)

Co-investorsACActivant CapitalASAscenta CapitalBABalderton CapitalFOForesite CapitalGLGlobal BioAccess FundGRGreatPoint Ventures+9 more

OnCusp Therapeutics develops oncology therapeutics for cancer treatment, including antibody-drug conjugates and small molecule compounds in clinical and preclinical stages.

BiotechMedical DevicesNew York, US

Dr. Bing Yuan(Co-Founder, Chief Executive Officer)Dr. Eric Slosberg(Co-Founder, Chief Development Officer)Dr. Andy Fu(Co-Founder, Chief Business Officer)Bing Yuan, Ph.D., MBA(Co-Founder, Chief Executive Officer)Eric Slosberg, Ph.D.(Co-Founder, Chief Development Officer)Andy Fu, PharmD, MBA(Co-Founder, Chief Business Officer)

Co-investorsOROrbiMedF-F-Prime CapitalSOSofinnova VenturesDEDe Novo VenturesINInsight PartnersNVNVIDIA

AI company developing a medical search engine used by physicians for clinical decision support.

DNDaniel Nadler(Founder)inZZZachary Ziegler(Founder)Daniel Nadler Zachary Ziegler(Founder)Zack Ziegler(Founder)

Co-investorsALAlkeon InnovationAMAmity VenturesANAndreessen HorowitzBABas1s VenturesBOBond Capital ManagementBRBreyer Capital+26 more

Orasis is a pharmaceutical company developing drugs for the eye, operating in the ophthalmology and eyecare space.

BiotechHealthtechMedical Devices

Co-investorsARArboretum VenturesMAMaverick Ventures IsraelVIVisionary VenturesCACatalio Capital ManagementJOJohnson & Johnson Innovation – JJDCLILifeSci Venture Partners+1 more

Perfuse Therapeutics develops novel ocular therapies for retinal and glaucoma diseases through drug delivery and formulation platforms.

BiotechHealthtechMedical DevicesSan Francisco, US

SGSevgi Gurkan(Founder, Chief Executive Officer, and Member of the Board of Directors)in

BoardChristy Shaffer(Director)CKChau Khuong(Director)in

Co-investorsOROrbiMedACAccess BiotechnologyHAHatteras Venture PartnersLALAVLILilly Asia VenturesHAHatteras

A precision oncology company providing genomic testing and resources to support cancer care decisions, operating under Labcorp Oncology.

BiotechDigital HealthHealthtechMedical DevicesBaltimore, US

VVVictor Velculescu(Executive Officer, Director, Promoter)inLuis A. Diaz, Jr.(Executive Officer, Director, Promoter)SASam Angiuoli(Executive Officer)inSJSian Jones(Executive Officer)inLisa Kann(Executive Officer)inAnthony Newton(Executive Officer)

Co-investors3B3B Future Health FundCOCo-Win VenturesNENew Enterprise Associates (NEA)WIWindham Capital PartnersVEVensana Capital

Pheast Therapeutics develops immunotherapies targeting cancer, building on foundational research from Stanford's stem cell research institute.

BiotechHealthtechMedical DevicesRedwood City, US

IWIrv Weissman(Cofounder, Scientific Advisor, Board Director)RMRavi Majeti(Cofounder, Scientific Advisor, Board Observer)ABAmira Barkal(Principal Founder, Scientific Advisor, Board Director)inRMRoy Maute(Cofounder & Chief Executive Officer)in

BoardJVJacob Vogelstein(Director)SGSteven Gillis(Director)in

Co-investorsARARCH Venture PartnersALAlexandriaCACatalio Capital Management

Pillar Biosciences develops kitted next-generation sequencing (NGS) panels and its SLIMamp single-tube library preparation technology for clinical and research laboratories, focused on cancer diagnostics.

BiotechDigital HealthHealthtechMedical DevicesNatick, US

Shawn Liu(Director)Hui Yang(Director)Gang Song(Executive Officer, Director)Zhaohui Wang(Director)Robert Forrester(Director)inHong Fang Song(Director)

Co-investorsHBHB VenturesBABain Capital Life SciencesSOSoleus Capital

PinkDx is a diagnostics company developing tests, led by a leadership team spanning scientific, medical, and business functions.

BiotechDigital HealthFemTechIndianapolis, US

RTRichard T. Kloos(Chief Medical Officer)inTMTimothy McMeekan(Co-Founder, Chief Financial Officer, and Chief Business Officer)GKGiulia Kennedy(Founder)IRIsaac Ro(Director)inRSRisa Stack(Director)inEric Wang(Executive Officer)

Co-investorsBEBEVCBLBlue Venture FundsMOMountain Group CapitalSASandbox Industries

Port Therapeutics is a company focused on cancer immunotherapy development.

BiotechHealthtech

LGLena Gamboa(Head of Cancer Immunotherapy)inSASteve Altschuler(Executive Chair)in

PrognomiQ is a clinical-stage company developing blood-based tests for early detection and treatment of cancer and other complex diseases using multi-omics data.

AI & Machine LearningBiotechHealthtechSan Mateo, US

PMPhilip Ma, Ph.D.(Executive Officer, Director)Philip Ma(Chief Executive Officer & Founder)inOFOmid Farokhzad(Chair of the Board of Directors)inDavid Siewers(Chief Financial Officer)inBrian Koh(Chief Medical Officer)inBruce Wilcox(Chief Technology Officer)in

Co-investorsAMaMoonWIWingMAMaverick Ventures

ProSomnus offers oral appliance devices for treating obstructive sleep apnea and snoring, positioned as an alternative to CPAP machines.

Digital HealthHealthtechMedical DevicesWellness & FitnessPleasanton, US

Leonard Liptak(Executive Officer, Director)Sung Kim(Executive Officer)Jason Orchard(Director)Steven Pacelli(Director)Heather Rider(Director)Laing Rikkers(Executive Officer, Director)

Co-investorsCACatalio Capital ManagementSPSpring Mountain Capital

Recognify is a biotech company developing therapeutic and diagnostic products for CNS disease, oncology, and infectious disease.

BiotechDigital HealthMental Health

GWGary Walker(Founder, VP Clinical Development)inTCThomas C. Südhof(Founder, Chairman of SAB)Angela Macfarlane(Founder, Board Member, Business Advisor)MPMatt Pando(Founder, CEO/President)in

Co-investorsATatai Life Sciences

RefleXion Medical develops SCINTIX autonomous radiotherapy, an external beam theranostic oncology platform that uses biological signals from radiopharmaceutical-labeled cancer cells to deliver real-time, motion-managed radiation to lung and bone tumors from primary or metastatic disease.

BiotechHealthtechMedical DevicesHayward, US

Samuel Mazin(Executive Officer, Director)inAkshay Nanduri(Executive Officer, Director)in

BoardJWJay Watkins(Director)in

Co-investorsASAscension VenturesPFPfizer Venture InvestmentsSOSofinnova PartnersSOSonder CapitalVEVenrock

Centenara Labs develops longevity drugs and therapies by translating aging research into novel medical treatments aimed at improving healthy aging.

BiotechDeep TechHealthtechLongevity

Christian Angermayer(Founder)Shannon Thyme KlingerEtienne

Co-investorsQCQC·VENTURES

Resilience is a contract development and manufacturing organization (CDMO) that manufactures complex pharmaceutical products and active pharmaceutical ingredients to broaden access to medicines and protect biopharmaceutical supply chains against disruption.

Advanced ManufacturingBiotechEnterprise SoftwareBlue Ash, US

William S. Marth(Chief Executive Officer)William S. Marth, RPh., MBA(President & CEO)

BoardRNRobert Nelsen(Chairman, Resilience; Founder, ARCH)

Co-investors8V8VCARARCH Venture PartnersGLGlobal Health Investment CorporationGVGV (Google Ventures)KOKoch Disruptive TechnologiesLULux Capital+14 more

Rhapsogen is developing a precision biologic therapy aimed at treating autoimmune diseases, focused on efficacy, safety, and durability.

BiotechHealthtech

Co-investorsCACatalio Capital Management

Satellite Bio develops an off-the-shelf cell therapy that delivers functional liver cells (hepatocytes) into the body, where they engraft to restore liver function.

BiotechHealthtechCambridge, US

CCChristopher Chen(Director, Promoter)inThomas Lowery(Executive Officer)

BoardEllie McGuire(Director)Ling Wong(Director)Sujata Bhatia(Director)William Young(Director)

Co-investorsALAlumni VenturesAMaMoonLILightspeed Venture PartnersHIHighbury HoldingsPOPolaris PartnersS3S32

Septerna is a biotechnology company that uses its proprietary Native Complex Platform to discover and develop oral small molecule therapies targeting GPCRs for endocrinology, immunology and inflammation, and metabolic diseases.

AI & Machine LearningBiotechDeep TechSouth San Francisco, US

Robert Lefkowitz(Founder)Arthur Christopoulos(Founder)Patrick Sexton(Founder)RXRan Xiao(Executive Officer)inElizabeth Bhatt(Executive Officer)SSSamira Shaikhly(Executive Officer)in

Co-investorsRARA CapitalSASamsara BioCapitalVEVertex Ventures HCTHThird Rock Ventures

SetPoint Medical develops an FDA-approved implantable neurostimulation device that stimulates the vagus nerve to reduce inflammation, offering a device-based treatment for adults with moderate-to-severe rheumatoid arthritis who have not responded to biologic or targeted synthetic drugs.

BiotechHealthtechMedical DevicesValencia, US

MSMurthy Simhambhatla(CEO)inDCDavid Chernoff(Chief Medical Officer (MD))YLYaakov Levine(PhD)inRSRohan Seth(Executive Officer)inKevin Tracey(Founder)

BoardBWBlake Wu(Director)in

Co-investorsALAlly Bridge GroupNENew Enterprise Associates (NEA)NONorwest Venture PartnersTOTopspin PartnersASAsahi Kasei Corporate Venture CapitalCICitta Capital+8 more

HealthtechCambridge, US

RDRahul Dhanda(Executive Officer, Director)inJCJames Collins(Director)DWDavid Walt(Director)in

BoardIRIssi Rozen(Director)in

Co-investorsGAGaingelsILIllumina VenturesCACatalio Capital ManagementGOGood VenturesGVGV (Google Ventures)NONorthpond Ventures+1 more

Sidera Bio is a biotechnology company using human genetics to develop new medicines for patients.

Biotech

Co-investorsRARA CapitalFOForbionNONovo Holdings

Singular Genomics develops spatial pathology technology to map molecules and cells directly in tissue for disease characterization.

BiotechDeep TechMedical DevicesSan Diego, US

John Stark(CEO)ABAaron Berlin(CTO)in

Co-investorsARARCH Venture PartnersCOCoatue ManagementF-F-Prime Capital

HealthtechBaltimore, US

Carolyn Reed Yarina(Executive Officer, Director)Katherine Kirsch(Executive Officer, Director)GHGillian Henker(Executive Officer, Director)in

Co-investorsBEBelle Impact FundWHWhoa I Lp, By: Whoa VenturesCACamden PartnersCACatalio AccessGOGolden SeedsRERevolution+1 more

Somethings connects teenagers with peer mentorship support to address gaps in mental health access in the United States.

Digital HealthHealthtechMental HealthWellness & Fitness

PGPatrick Gilligan(Founder)in

Co-investorsCOCoalition OperatorsGAGaingelsGEGeneral CatalystMAMana VenturesPLPlug and Play VenturesTATau Ventures+4 more

Synthio Labs develops AI-powered synthesis and clinical interpretation systems for pharmaceutical interactions, offering text, voice, and video interfaces designed for healthcare professionals and patients that integrate FDA labels, drug mechanisms, and clinical literature.

AI & Machine LearningBiotechDigital HealthHealthtechSan Francisco, US

SDSupreet Deshpande(CEO)inSSSahitya Sridhar(Founder)inRVRajashekar Vasantha(CTO)inRajashekhar Vasantha(Founder)Supreet Deshpande Sahitya Sridhar(Founder)Jarvis Nguyen(s Office Associate)

Co-investorsELElevation CapitalPEPeak XV PartnersPIPioneerY Y Combinator191984 Ventures Management, LlcLLLlama ventures