Maryland TEDCO

aBreak Music is a free music and artist discovery platform for independent artists. It connects emerging talent with industry expertise from experienced music executives.

B2B MarketplacesCreator EconomyMedia & Entertainment

Aidar develops digital medicine and precision medicine solutions that connect patients, clinicians, and healthcare systems to improve health outcomes. The company serves providers, life sciences companies, and payers with tools for treatment optimization, clinical trial support, and population health management.

AI & Machine LearningDigital HealthHealthtech

Aloe Therapeutics develops AIM-001, a localized cell-based immunotherapy implanted at tumor sites during surgery to activate the immune system and improve response to checkpoint immunotherapy in patients with advanced solid tumors.

BiotechMedical Devices

Aphage develops AI and sensor technologies to identify, track, and classify physical threats across borders, infrastructure, and transportation networks for government and security organizations.

AI & Machine LearningDefense TechGovTech

AquaLith manufactures advanced battery materials and next-generation batteries with faster charging times, improved safety, higher energy density, and lower costs for consumer electronics and electric vehicles. The company's lithium-ion technology operates efficiently at very low temperatures and extends beyond current market capabilities.

EnergyHardwareNew MaterialsCollege Park, US

Ardent Privacy provides data privacy compliance and security software for enterprises across multiple industries. The platform helps organizations implement privacy programs, achieve regulatory compliance, and manage data governance across jurisdictions globally.

CybersecurityData & InfrastructureEnterprise Software

ARMR Systems develops a wearable vascular clamp system for rapid hemorrhage control in trauma situations where medical help is not immediately available. The technology is designed for soldiers, first responders, and emergency personnel to stop life-threatening bleeding without advanced medical training.

Defense TechHealthtechMedical Devices

Astek Diagnostics develops a diagnostic platform for rapid and accurate detection of urinary tract infections and related conditions in clinical specimens. The company serves physicians and patients needing point-of-care diagnostic solutions for infectious diseases.

AI & Machine LearningDigital HealthHealthtechMedical DevicesBaltimore, US

Mustafa Al-Adhami(CEO)

Mimecast provides a platform for securing humans, data, and AI within organizations. The company serves enterprise customers seeking protection and secure work environments.

AI & Machine LearningCloud ComputingCybersecurityEnterprise Software

Ranjan Singh(CEO)

Balance Theory provides a platform that manages cybersecurity investment programs end-to-end, including decision-trigger detection, cost and coverage optimization, and program rationalization. The company serves enterprise security budget owners across multiple industries seeking to align cybersecurity spending with strategic business objectives.

CybersecurityEnterprise SoftwareSaaS

Banadura Systems provides a network security platform that blocks malicious traffic and DNS threats across devices and networks. The solution serves small businesses, enterprises, managed service providers, and remote workforces.

Cybersecurity

Beyond Commissions provides software for revenue and commission accounting, designed for wealth management and life insurance companies to automate payment processing, reconciliation, and financial operations.

Enterprise SoftwareFintechSaaS

BlockSynop develops a non-invasive real-time monitoring device for anesthesiologists to objectively measure the effectiveness of local anesthetics during clinical procedures. The Neural Blockade Monitor enables quantitative assessment of nerve blocks to improve pain management outcomes and reduce procedural complications.

HealthtechMedical Devices

BondTrue develops medical devices through design and development services. The company serves medical device manufacturers and is funded by the National Science Foundation.

Medical DevicesBaltimore, US

OpenText provides enterprise information management, content management, and cybersecurity solutions powered by AI, serving large organizations across multiple industries. The company offers data unification, compliance and governance, AI-ready content management, and network detection and response capabilities for hybrid and cloud environments.

AI & Machine LearningCybersecurityEnterprise Software

BullFrog AI develops software that harmonizes fragmented biomedical data and applies machine learning to uncover patterns, biomarkers, and drug targets from clinical trial and multi-omics datasets for pharmaceutical R&D teams.

AI & Machine LearningBiotechData & Infrastructure

Vin Singh

Capsulomics offers Esopredict, a DNA methylation-based risk-stratification test that predicts progression from Barrett's esophagus to high-grade dysplasia or esophageal adenocarcinoma for gastroenterologists and pathologists. The test is used as a secondary option when the company's primary TissueCypher spatialomics test cannot provide results.

AI & Machine LearningDigital HealthMedical Devices

CarrTech Corp manufactures FROG, an FDA-cleared medical device that combines a filter and hypodermic needle to safely prepare injectable medications from glass ampoules. The device is designed for healthcare providers to reduce contamination, needle stick injuries, and preparation delays in hospital and clinical settings.

Medical Devices

Cartesian Therapeutics develops mRNA-based cell therapies for autoimmune diseases. The company is a clinical-stage biotech firm focused on advancing immunology treatments through its proprietary mRNA platform.

BiotechHealthtech

Celcy manufactures a smart oven and freezer appliance that autonomously cooks pre-loaded meals on a remote schedule, allowing users to prepare food without being physically present. It serves consumers seeking time savings and healthy meal options through automation technology.

ConsumerHardware

Cerebro Capital provides a technology-enabled platform for commercial lending that connects businesses with lenders to simplify and accelerate the business loan process. The company aims to make access to capital easier, faster, and more equitable for mid-sized businesses.

B2B MarketplacesEnterprise SoftwareFintechSaaSBaltimore, US

Matthew Bjonerud(Founder & CEO)

Cide Kic is a digital kitchen management platform that uses pictorial interfaces to help chefs and kitchen teams track recipes, menus, food safety, and food waste. The product is designed specifically for professional kitchen workflows and restaurant operations.

Enterprise SoftwareFoodTech

Not applicable - this is a media/news site

Clymb develops emotional wellness programs for young people to build resilience, emotional intelligence, and reduce stress. The company targets schools and youth populations to prevent mental health and behavioral disorders.

EdTechHealthtechHR TechMental HealthWellness & FitnessBaltimore, US

Ashley Williams(Founder)

Common Curriculum offers a digital lesson planning and collaboration platform for teachers and school administrators. The tool helps educators organize lessons, share resources, and manage curriculum planning.

EdTech

CoolStat is an investigational medical device that delivers dry air through the nasal passages to cool patients with fever and other conditions, currently being studied in clinical trials for neurogenic fever, cardiac arrest, and migraine pain management.

Digital HealthHealthtechMedical Devices

An AI-powered mobile app that recommends restaurants and recipes based on user preferences, dietary restrictions, and mood. The app enables group decision-making for dining and cooking with personalized suggestions for different users' dietary needs.

AI & Machine LearningConsumerFoodTech

Curbio manages home preparation and improvement services for real estate agents, teams, and brokers. The platform coordinates repairs, refreshes, renovations, and exterior updates for properties being listed for sale, with flexible payment options including pay-at-closing for sellers.

B2B MarketplacesPropTech

CyDeploy provides a platform that uses automated asset discovery, digital twins, and AI-driven testing to help organizations understand the impact of technology changes like patches and digital transformations on their environment. The platform serves enterprise IT and operations teams seeking to implement changes confidently through environment verification and compatibility checks.

AI & Machine LearningCybersecurityDeveloper ToolsEnterprise SoftwareLaurel, US

Datakwip connects building data sources (BAS, meters, sensors, weather) and deploys AI agents to automatically identify energy savings, detect equipment faults, and generate compliance reports. The platform eliminates the need for site drawings, custom code, and domain experts by using AI to map data points and generate building intelligence continuously.

AI & Machine LearningCleantechPropTech

Dockshare is a peer-to-peer marketplace that connects private dock owners with boaters seeking short-term or long-term dock rentals. The platform enables dock owners to monetize unused waterfront property while providing boaters flexible access to docking locations.

ConsumerMarketplacesPropTech

Nate Young

Dogwood Gaming develops video games and AI-powered game development tools for creators. The company creates games across multiple genres (adventure, party brawlers, RPGs) and offers developer-focused products like EveryMan AI for character creation and the Dogwood Companion System for scaling AI-controlled characters.

AI & Machine LearningDeveloper ToolsGamingRockville, US

Dynamic Dimension Technologies develops VxSIM, a high-fidelity simulation platform for testing autonomous systems, robotics, and control algorithms in defense and industrial applications. The company provides engineering and software solutions to government and commercial clients, with particular experience supporting the U.S. military branches.

Defense TechDeveloper ToolsRobotics

EcoMap builds a software platform that provides connective infrastructure for entrepreneurial ecosystems, helping regional economic development organizations, state agencies, and business support organizations make their programs discoverable and interconnected for small business owners.

AI & Machine LearningData & InfrastructureGovTechImpact & Social GoodMarketing TechSaaSWilmington, US

Pava LaPere(Founder)Sherrod Davis(CEO)

Elixir Therapeutics develops therapies for rare diseases and aging-related conditions using proprietary technologies, including ZSCAN4 for telomere extension in stem cell therapies and Bobcat mRNA for delivering large genes. The company is advancing clinical candidates for telomere biology disorders and Duchenne muscular dystrophy.

BiotechLongevityMedical Devices

Minoru Ko(Chief Scientific Officer)

eMedicalSentry provides remote patient monitoring and telehealth solutions for hospitals and healthcare providers to reduce hospital readmissions and improve patient outcomes. The platform integrates patient monitoring devices, care coordination, and real-time communication between patients and care teams.

Digital HealthHealthtechSaaS

Ensemble Consultancy is a technology consulting firm specializing in digital modernization, artificial intelligence, and cloud infrastructure solutions. The company serves federal agencies, universities, and enterprises with services including data platforms, machine learning deployment, cloud architecture, and human-centered digital experiences.

AI & Machine LearningCloud ComputingEnterprise Software

EpiWatch is an FDA-cleared seizure detection app for Apple Watch that monitors for tonic-clonic seizures and sends real-time alerts to users and their caregivers. The app is designed for people with epilepsy in the United States to help reduce the risk of sudden unexpected death in epilepsy (SUDEP) and enable faster intervention.

Digital HealthHealthtechMedical Devices

FintechNewark, US

Escalate provides support solutions for businesses managing hourly and frontline workers, focusing on reducing turnover and increasing productivity to drive profitability and business growth.

EdTechEnterprise SoftwareFintechHR TechSilver Spring, US

Sienna Daniel(Cofounder & President)Sean Segal(Cofounder & CEO)

Eyrus provides an AI-driven construction management platform that handles worker registration, time tracking, access control, video surveillance, and onboarding for construction sites. The platform serves project managers, safety managers, superintendents, owners, and field teams across the construction industry.

AI & Machine LearningConstruction Tech

Xometry provides an instant quoting and manufacturing platform that connects startups and enterprises with a global network of manufacturers to produce precision components from prototype through high-volume production.

Advanced ManufacturingB2B MarketplacesSaaSUnknown, US

FanzPlay is a mobile social gaming app where fans compete in real-time trivia and knowledge-based games about their favorite sports teams and performers, with prizes and live scoreboard displays during events.

GamingSocial

Femly supplies organic cotton period care products (tampons and pads) to offices, schools, airports, and hospitality venues to improve workplace wellness and accessibility for employees and visitors.

FemTechWellness & Fitness

FlexNode provides modular AI infrastructure solutions designed for rapid deployment at the edge. The company delivers turnkey facilities, IT systems, and operational support for AI workloads, optimized for both hyperscaler quality and edge inference deployment.

AI & Machine LearningCloud ComputingDeep Tech

FlixMate is a community-powered app that enables TV and movie fans to discover, share, and track content across streaming platforms in a centralized social interface.

ConsumerMedia & EntertainmentSocial