/Companies

SetPoint Medical

Valencia, US · 125 employees on LinkedIn · 15 known investors

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SetPoint Medical develops an FDA-approved implantable neurostimulation device that stimulates the vagus nerve to reduce inflammation, offering a device-based treatment for adults with moderate-to-severe rheumatoid arthritis who have not responded to biologic or targeted synthetic drugs. The company applies this "neuroimmune modulation" approach to autoimmune disease care.

Founders & leadership

MSMurthy Simhambhatla
Murthy SimhambhatlaCEO
DCDavid Chernoff
David ChernoffChief Medical Officer (MD)
YLYaakov Levine
Yaakov LevinePhDYaakov Levine holds a PhD and leads the development of neuroimmune modulation therapies for chronic inflammatory diseases including rheumatoid arthritis and inflammatory bowel disease at SetPoint Medical.
RSRohan Seth
Rohan SethCFO
KT
Kevin TraceyFounder

Board

BWBlake Wu
Blake WuBoard directorPartner at New Enterprise Associates (NEA)
JMJuan-Pablo Mas
Juan-Pablo MasBoard DirectorPartner at Action Potential Venture Capital Ltd.
ZSZack Scott
Zack ScottBoard directorGeneral Partner at Norwest Venture Partners
SJ
Steven J WinickBoard director
HPHank Plain
Hank PlainBoard directorFounding Partner & Advisor at Lightstone Ventures
AWAllan Will
Allan WillChair of the Board of DirectorsExecutive Chair at EBR Systems

Investors · 15

Reported raises · per SEC filings

Form D private placements

$290.8M disclosed across 5 rounds · 2015–2025

▶$115.5MraisedOct 2025 · 24 investors · Other Health Care
Rule 506(b)
Officers, directors & promoters on the filing
  • David ChernoffExecutive Officer
  • Murthy SimhambhatlaExecutive Officer, Director
  • Zack ScottDirector
  • Allan WillDirector
  • Steven J WinickDirector
  • Rohan SethExecutive Officer
  • Tyler BinneyDirector
  • Kevin ReillyDirector
  • Hank PlainDirector
  • Blake WuDirector
  • Josh MakowerDirector
  • Juan-Pablo MasDirector
Offering amount
$115.5M
Amount sold
$115.5M
First sale
Mar 2025
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$80MraisedFeb 2025 · 21 investors · Other Health Care
Rule 506(b)
Officers, directors & promoters on the filing
  • Blake WuDirector
  • Murthy SimhambhatlaExecutive Officer, Director
  • David ChernoffExecutive Officer
  • Juan-Pablo MasDirector
  • Rohan SethExecutive Officer
  • Zack ScottDirector
  • Steven J WinickDirector
  • Allan WillDirector
  • Hank PlainDirector
Offering amount
$80M
Amount sold
$80M
First sale
Jan 2023
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$64.4MraisedFeb 2021 · 26 investors · Other Health Care
Rule 506(b)
Officers, directors & promoters on the filing
  • Josh MakowerDirector
  • Murthy SimhambhatlaExecutive Officer, Director
  • Alan WillDirector
  • Hank PlainDirector
  • Juan-Pablo MasDirector
  • Colin MorrisonDirector
  • Steven J. WinickDirector
  • William DaiDirector
Offering amount
$64.4M
Amount sold
$64.4M
Minimum investment
$1
First sale
Oct 2020
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$15.7MraisedSep 2019 · 8 investors · Other Health Care
Rule 506(b)
Officers, directors & promoters on the filing
  • Joe BillerDirector
  • Steven J. WinickDirector
  • Allan WillDirector
  • Hank PlainDirector
  • Juan-Pablo MasDirector
  • Josh MakowerDirector
  • Murthy SimhambhatlaExecutive Officer, Director
Offering amount
$20.5M
Amount sold
$15.7M
Minimum investment
$1
First sale
Sep 2019
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$15.1MraisedSep 2015 · 7 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Hank PlainDirector
  • David NeustaedterDirector
  • Bill GearyDirector
  • Juan-Pablo MasDirector
  • Anthony ArnoldExecutive Officer, Director
  • Alan WillDirector
  • Christopher KasterDirector
  • Steven WinickDirector
Offering amount
$15.1M
Amount sold
$15.1M
First sale
Aug 2015
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Founder mafia

2 people who came through SetPoint Medical went on to found or lead other companies.

Related companies · 2

Companies working in the same space as SetPoint Medical.

Frequently asked questions

What does SetPoint Medical do?
SetPoint Medical develops an FDA-approved implantable neurostimulation device that stimulates the vagus nerve to reduce inflammation, offering a device-based treatment for adults with moderate-to-severe rheumatoid arthritis who have not responded to biologic or targeted synthetic drugs. The company applies this "neuroimmune modulation" approach to autoimmune disease care.
Who are SetPoint Medical's investors?
SetPoint Medical's investors include Ally Bridge Group, New Enterprise Associates (NEA), Norwest Venture Partners, Topspin Partners, Asahi Kasei Corporate Venture Capital, Catalio Capital Management, LP, Citta Capital, Lightstone Ventures and 7 more.
How much funding has SetPoint Medical raised?
SetPoint Medical has disclosed $290.8M raised across 5 rounds.
Where is SetPoint Medical headquartered?
SetPoint Medical is headquartered in Valencia, US.