Amalgam
Wilmington, US · Founded 2016 · Delaware corporation · 51 employees on LinkedIn · 3 known investors
Amalgam builds a modular, AI-powered Software as a Medical Device (SaMD) platform and EHR-integrated solutions for life sciences companies, health plans, and providers to support clinical decisions, patient engagement, and digital therapeutics. It also acts as Manufacturer of Record for regulated software, holding regulatory clearance across four continents.
Founders & leadership
Amalgam was founded in 2016 by RYAN A. SYSKO and Ryan Sysko.
RA
RYAN A. SYSKOCo-founder
RS
Ryan SyskoFounder
Board
SV
SONNY VUBoard director
JP
JEFFREY P. COURTNEYBoard director
Investors · 3
Reported raises · per SEC filings
Form D private placements$27.3M disclosed across 5 rounds · 2016–2025
▶$7.9MraisedAug 2025 · 28 investors · Other Health CareRule 506(b)
▶$7.9MraisedAug 2025 · 28 investors · Other Health Care
Rule 506(b)Officers, directors & promoters on the filing
- SONNY VUDirector
- JEFFREY P. COURTNEYDirector
- RYAN A. SYSKOExecutive Officer, Director
- Offering amount
- $7.9M
- Amount sold
- $7.9M
- Sales commissions
- $616.3K
- Placement agents
- ERG SECURITIES (US) LLC
- First sale
- Aug 2025
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$17.4MraisedJan 2023 · 62 investors · Other Health CareRule 506(b)
▶$17.4MraisedJan 2023 · 62 investors · Other Health Care
Rule 506(b)Officers, directors & promoters on the filing
- Sonny VuDirector
- Ryan SyskoExecutive Officer, Director
- Jeffrey CourtneyDirector
- Offering amount
- $45M
- Amount sold
- $17.4M
- First sale
- Dec 2022
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$650KraisedOct 2019 · 5 investors · Other Health CareRule 506(b)
▶$650KraisedOct 2019 · 5 investors · Other Health Care
Rule 506(b)Officers, directors & promoters on the filing
- Ryan A SyskoExecutive Officer, Director
- Sarwar IslamDirector
- Offering amount
- $750K
- Amount sold
- $650K
- First sale
- Sep 2019
- Incorporated
- Corporation, Delaware, 2016
- Federal exemptions
- 06b
▶$1.2MraisedMay 2019 · 27 investors · Other Health CareRule 506(b)
▶$1.2MraisedMay 2019 · 27 investors · Other Health Care
Rule 506(b)Officers, directors & promoters on the filing
- Sarwar IslamDirector
- Ryan A SyskoExecutive Officer, Director
- Offering amount
- $2M
- Amount sold
- $1.2M
- Finders' fees
- $9.4K
- Placement agents
- Steven Sarigianis
- First sale
- Jun 2017
- Incorporated
- Corporation, Delaware, 2016
- Federal exemptions
- 06b
▶$215KraisedMar 2016 · 7 investors · Other Health CareRule 506(b)
▶$215KraisedMar 2016 · 7 investors · Other Health Care
Rule 506(b)Officers, directors & promoters on the filing
- Ryan Adam SyskoExecutive Officer, Director
- Offering amount
- $500K
- Amount sold
- $215K
- Minimum investment
- $25K
- Proceeds to insiders
- $105K
- First sale
- Mar 2016
- Incorporated
- Corporation, Delaware, 2016
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Competitors · 3
by search overlap
Rula31 shared keywordsRula operates a digital mental health platform connecting patients with licensed therapists for remote behavioral care. The platform serves individuals seeking mental healthcare and partners with insurers to make therapy accessible and affordable.
Medscape30 shared keywordsMedscape is an online medical information platform providing clinical news, expert perspectives, case studies, quizzes, and reference material across specialties such as cardiology, oncology, neurology, and psychiatry. It serves physicians, nurses, pharmacists, residents, and medical students.
Aacap29 shared keywordsThe American Academy of Child and Adolescent Psychiatry (AACAP) is a professional medical organization focused on child and adolescent mental health, publishing resources and policy statements on topics such as youth suicide, screen media use, autism spectrum disorders, and access to care. It provides guidance for families, clinicians, and policymakers on pediatric psychiatric issues.
Companies competing with Amalgam for the same Google search keywords, organic and paid, via search-intersection analysis.
Frequently asked questions
- What does Amalgam do?
- Amalgam builds a modular, AI-powered Software as a Medical Device (SaMD) platform and EHR-integrated solutions for life sciences companies, health plans, and providers to support clinical decisions, patient engagement, and digital therapeutics. It also acts as Manufacturer of Record for regulated software, holding regulatory clearance across four continents.
- Who founded Amalgam?
- Amalgam was founded by RYAN A. SYSKO, Ryan Sysko in 2016.
- Who are Amalgam's investors?
- Amalgam's investors include Catalio Capital Management, LP, CVS Health Ventures, Supermorpheus.
- How much funding has Amalgam raised?
- Amalgam has disclosed $27.3M raised across 5 rounds.
- Where is Amalgam headquartered?
- Amalgam is headquartered in Wilmington, US.