Fractyl
NASDAQ: GUTSLexington, US · Founded 2010 · Delaware corporation · 106 employees on LinkedIn · 9 known investors
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Fractyl develops therapies for obesity and type 2 diabetes, focusing on non-drug-based approaches rooted in understanding metabolic disease mechanisms. The company serves patients and the physician community seeking alternatives to lifelong pharmaceutical treatments.
Founders & leadership
Fractyl was founded in 2010 by HARITH RAJAGOPALAN, JAY CAPLAN, Jay Caplan, and Harith Rajagopalan.





Board


Investors · 9
Reported raises · per SEC filings
Form D private placements$275.7M disclosed across 6 rounds · 2014–2022
▶$20.1MraisedJan 2022 · 4 investors · OtherRule 506(b)
- ALLAN WILLDirector
- JUAN CARLOS LOPEZ-TALAVERAExecutive Officer
- CLIVE MEANWELLDirector
- LISA DAVIDSONExecutive Officer
- HARITH RAJAGOPALANExecutive Officer, Director
- WILLIAM BRADLEYDirector
- BRIAN DOVEYDirector
- KELLY BARNESDirector
- AMY SCHULMANDirector
- JAY CAPLANExecutive Officer
- MARC ELIADirector
- AJAY ROYANDirector
- Offering amount
- $20.1M
- Amount sold
- $20.1M
- First sale
- Jan 2022
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$100MraisedJun 2021 · 15 investors · Other Health CareRule 506(b)
- WILLIAM BRADLEYDirector
- JUAN CARLOS LOPEZ-TALAVERAExecutive Officer
- ALLAN WILLDirector
- CLIVE MEANWELLDirector
- MARGARET BORYSExecutive Officer
- JAY CAPLANExecutive Officer
- MICHAEL HUANGDirector
- LISA DAVIDSONExecutive Officer
- MARC ELIADirector
- HARITH RAJAGOPALANExecutive Officer, Director
- BRIAN DOVEYDirector
- AJAY ROYANDirector
- AMY SCHULMANDirector
- Offering amount
- $100M
- Amount sold
- $100M
- First sale
- Jun 2021
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$44.8MraisedMar 2020 · 15 investors · Other Health CareRule 506(b)
- WILLIAM BRADLEYDirector
- AMY SCHULMANDirector
- JUAN CARLOS LOPEZ-TALAVERAExecutive Officer
- HARITH RAJAGOPALANExecutive Officer, Director
- JAY CAPLANExecutive Officer
- MARGARET BORYSExecutive Officer
- LISA DAVIDSONExecutive Officer
- JOHN AMATRUDADirector
- CHRISTOPHER GABRIELIDirector
- STANLEY LAPIDUSDirector
- AJAY ROYANDirector
- BRIAN DOVEYDirector
- ALLAN WILLDirector
- Offering amount
- $44.8M
- Amount sold
- $44.8M
- Finders' fees
- $468K
- First sale
- Mar 2020
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$44MraisedDec 2017 · 19 investors · Other Health CareRule 506(b)
- STANLEY LAPIDUSDirector
- HARITH RAJAGOPALANExecutive Officer, Director
- CHRISTOPHER GABRIELIDirector
- LISA DAVIDSONExecutive Officer
- AJAY ROYANDirector
- JOHN AMATRUDADirector
- ALLAN WILLDirector
- BRIAN DOVEYDirector
- JAY CAPLANExecutive Officer
- WILLIAM BRADLEYDirector
- Offering amount
- $44M
- Amount sold
- $44M
- Finders' fees
- $250K
- First sale
- Jun 2017
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$47.2MraisedFeb 2016 · 16 investors · Other Health CareRule 506(b)
- ALLAN WILLDirector
- STANLEY LAPIDUSDirector
- NIMESH SHAHDirector
- CHRISTOPHER GABRIELIDirector
- AJAY ROYANDirector
- HARITH RAJAGOPALANExecutive Officer, Director
- JAY CAPLANExecutive Officer, Director
- LISA DAVIDSONExecutive Officer
- Offering amount
- $47.2M
- Amount sold
- $47.2M
- First sale
- Oct 2015
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$19.8MraisedSep 2014 · 13 investors · Other Health CareRule 506(b)
- Ajay RoyanDirector
- Christopher GabrieliDirector
- Jay CaplanExecutive Officer, Director
- Diane MarcouExecutive Officer
- Allan WillDirector
- Harith RajagopalanExecutive Officer, Director
- Stanley LapidusDirector
- Nimesh ShahDirector
- Offering amount
- $48.6M
- Amount sold
- $19.8M
- First sale
- Aug 2014
- Incorporated
- Corporation, Delaware, 2010
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Competitors · 2
by search overlapCompanies competing with Fractyl for the same Google search keywords, organic and paid, via search-intersection analysis.
In the news
Frequently asked questions
- What does Fractyl do?
- Fractyl develops therapies for obesity and type 2 diabetes, focusing on non-drug-based approaches rooted in understanding metabolic disease mechanisms. The company serves patients and the physician community seeking alternatives to lifelong pharmaceutical treatments.
- Who founded Fractyl?
- Fractyl was founded by HARITH RAJAGOPALAN, JAY CAPLAN, Jay Caplan, Harith Rajagopalan in 2010.
- Who are Fractyl's investors?
- Fractyl's investors include Bessemer Venture Partners, Catalio Capital Management, LP, Emergent Medical Partners, LLP, Mithril Capital Management, Domain Associates, General Catalyst, MITHRIL, Polaris Partners and 1 more.
- How much funding has Fractyl raised?
- Fractyl has disclosed $275.7M raised across 6 rounds.
- Where is Fractyl headquartered?
- Fractyl is headquartered in Lexington, US.




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