Fundraising Fox
Fractyl
NASDAQ: GUTSLexington, US · Founded 2010 · Delaware corporation · 106 employees on LinkedIn · 8 known investors
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Fractyl develops therapies for obesity and type 2 diabetes, focusing on non-drug-based approaches rooted in understanding metabolic disease mechanisms. The company serves patients and the physician community seeking alternatives to lifelong pharmaceutical treatments.
Founders & leadership
Fractyl was founded in 2010 by Jay Caplan and Harith Rajagopalan.
HR
Harith RajagopalanCo-Founder and CEOHarith Rajagopalan, M.D., Ph.D., is co-founder and CEO of Fractyl Health, which he started while an Entrepreneur-in-Residence at General Catalyst Partners; he was previously an academic cardiologist and physician-scientist. He holds a B.S. in chemistry from Stanford University, earned M.D. and Ph.D. degrees at Johns Hopkins School of Medicine where he researched intestinal cancers, trained in internal medicine and clinical cardiology at Brigham and Women's Hospital, and completed a research fellowship at the Harvard Stem Cell Institute.
LD
LISA DAVIDSONChief Financial Officer2015–2025Senior finance executive with experience scaling biotech, medtech, and specialty pharma companies from early development through IPO and public growth; previously held CFO roles and led over $1B in combined equity and debt financings across multiple life sciences organizations.
Board
AW
NS
CG
Christopher GabrieliBoard director
AR
SL
Stanley LapidusBoard director
Investors · 8
Bessemer Venture Partnerslisted by Bessemer Venture PartnersSan Francisco · $50K – $100M
How we know: Bessemer Venture Partners's portfolio page · the S-1 prospectus · the VCSheet dataset · open dataset · 5k.vc investor directory · Not right? Tell us
Catalio Capital Management, LPlisted by Catalio Capital Management, LPNew York
How we know: Catalio Capital Management, LP's portfolio page · Not right? Tell us
Emergent Medical Partners, LLPlisted by Emergent Medical Partners, LLPSan Jose
How we know: Emergent Medical Partners, LLP's portfolio page · Not right? Tell us
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General Catalystlisted by General CatalystSan Francisco · $30M
How we know: General Catalyst's portfolio page · the S-1 prospectus · open dataset · 5k.vc investor directory · Not right? Tell us
Mithril Capital Managementlisted by Mithril Capital ManagementAustin
How we know: Mithril Capital Management's portfolio page · the VCSheet dataset · open dataset · 5k.vc investor directory · Not right? Tell us
Domain AssociatesreportedPrinceton · $200K – $15M
How we know: the S-1 prospectus · open dataset · 5k.vc investor directory · Not right? Tell us
Reported raises · per SEC filings
Form D private placements$275.7M disclosed across 6 rounds · 2014–2022
▶$20.1MraisedJan 2022 · 4 investors · OtherRule 506(b)
▶$20.1MraisedJan 2022 · 4 investors · Other
Rule 506(b)Officers, directors & promoters on the filing
- ALLAN WILLDirector
- JUAN CARLOS LOPEZ-TALAVERAExecutive Officer
- CLIVE MEANWELLDirector
- LISA DAVIDSONExecutive Officer
- HARITH RAJAGOPALANExecutive Officer, Director
- WILLIAM BRADLEYDirector
- BRIAN DOVEYDirector
- KELLY BARNESDirector
- AMY SCHULMANDirector
- JAY CAPLANExecutive Officer
- MARC ELIADirector
- AJAY ROYANDirector
- Offering amount
- $20.1M
- Amount sold
- $20.1M
- First sale
- Jan 2022
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$100MraisedJun 2021 · 15 investors · Other Health CareRule 506(b)
▶$100MraisedJun 2021 · 15 investors · Other Health Care
Rule 506(b)Officers, directors & promoters on the filing
- WILLIAM BRADLEYDirector
- JUAN CARLOS LOPEZ-TALAVERAExecutive Officer
- ALLAN WILLDirector
- CLIVE MEANWELLDirector
- MARGARET BORYSExecutive Officer
- JAY CAPLANExecutive Officer
- MICHAEL HUANGDirector
- LISA DAVIDSONExecutive Officer
- MARC ELIADirector
- HARITH RAJAGOPALANExecutive Officer, Director
- BRIAN DOVEYDirector
- AJAY ROYANDirector
- AMY SCHULMANDirector
- Offering amount
- $100M
- Amount sold
- $100M
- First sale
- Jun 2021
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$44.8MraisedMar 2020 · 15 investors · Other Health CareRule 506(b)
▶$44.8MraisedMar 2020 · 15 investors · Other Health Care
Rule 506(b)Officers, directors & promoters on the filing
- WILLIAM BRADLEYDirector
- AMY SCHULMANDirector
- JUAN CARLOS LOPEZ-TALAVERAExecutive Officer
- HARITH RAJAGOPALANExecutive Officer, Director
- JAY CAPLANExecutive Officer
- MARGARET BORYSExecutive Officer
- LISA DAVIDSONExecutive Officer
- JOHN AMATRUDADirector
- CHRISTOPHER GABRIELIDirector
- STANLEY LAPIDUSDirector
- AJAY ROYANDirector
- BRIAN DOVEYDirector
- ALLAN WILLDirector
- Offering amount
- $44.8M
- Amount sold
- $44.8M
- Finders' fees
- $468K
- First sale
- Mar 2020
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$44MraisedDec 2017 · 19 investors · Other Health CareRule 506(b)
▶$44MraisedDec 2017 · 19 investors · Other Health Care
Rule 506(b)Officers, directors & promoters on the filing
- STANLEY LAPIDUSDirector
- HARITH RAJAGOPALANExecutive Officer, Director
- CHRISTOPHER GABRIELIDirector
- LISA DAVIDSONExecutive Officer
- AJAY ROYANDirector
- JOHN AMATRUDADirector
- ALLAN WILLDirector
- BRIAN DOVEYDirector
- JAY CAPLANExecutive Officer
- WILLIAM BRADLEYDirector
- Offering amount
- $44M
- Amount sold
- $44M
- Finders' fees
- $250K
- First sale
- Jun 2017
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$47.2MraisedFeb 2016 · 16 investors · Other Health CareRule 506(b)
▶$47.2MraisedFeb 2016 · 16 investors · Other Health Care
Rule 506(b)Officers, directors & promoters on the filing
- ALLAN WILLDirector
- STANLEY LAPIDUSDirector
- NIMESH SHAHDirector
- CHRISTOPHER GABRIELIDirector
- AJAY ROYANDirector
- HARITH RAJAGOPALANExecutive Officer, Director
- JAY CAPLANExecutive Officer, Director
- LISA DAVIDSONExecutive Officer
- Offering amount
- $47.2M
- Amount sold
- $47.2M
- First sale
- Oct 2015
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$19.8MraisedSep 2014 · 13 investors · Other Health CareRule 506(b)
▶$19.8MraisedSep 2014 · 13 investors · Other Health Care
Rule 506(b)Officers, directors & promoters on the filing
- Ajay RoyanDirector
- Christopher GabrieliDirector
- Jay CaplanExecutive Officer, Director
- Diane MarcouExecutive Officer
- Allan WillDirector
- Harith RajagopalanExecutive Officer, Director
- Stanley LapidusDirector
- Nimesh ShahDirector
- Offering amount
- $48.6M
- Amount sold
- $19.8M
- First sale
- Aug 2014
- Incorporated
- Corporation, Delaware, 2010
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Founder mafia
2 people who came through Fractyl went on to found or lead other companies.
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Frequently asked questions
- What does Fractyl do?
- Fractyl develops therapies for obesity and type 2 diabetes, focusing on non-drug-based approaches rooted in understanding metabolic disease mechanisms. The company serves patients and the physician community seeking alternatives to lifelong pharmaceutical treatments.
- Who founded Fractyl?
- Fractyl was founded by Jay Caplan, Harith Rajagopalan in 2010.
- Who are Fractyl's investors?
- Fractyl's investors include Bessemer Venture Partners, Catalio Capital Management, LP, Emergent Medical Partners, LLP, General Catalyst, Mithril Capital Management, Domain Associates, Polaris Partners, Veltro Argento.
- How much funding has Fractyl raised?
- Fractyl has disclosed $275.7M raised across 6 rounds.
- Where is Fractyl headquartered?
- Fractyl is headquartered in Lexington, US.