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National Institutes of Health (NIH)

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Investment thesis

The dominant non-dilutive funder of biotech and life-science startups: more SBIR/STTR awards than any other single agency component. Phase I typically ~$300k, Phase II $2M+, across therapeutics, diagnostics, devices, and digital health.

SBIR/STTR awards · non-dilutive funding

Federal grants and contracts to small businesses — no equity taken. Awards on record 1999–2023.

Awards
34,775
Companies funded
8,833
Total awarded
$18.7B
Median award
$252.6K

24,756 Phase I · 10,019 Phase II · 4,759 via STTR · most-funded states: CA, MA, MD, NY, NC

Recent awardeesPhaseYearAmount
TYMPANOGEN, INC.Richmond, VAPhase II2023$3.2M
PROTHERA BIOLOGICS, INC.Providence, RIPhase II2023$2.8M
ARIMA GENOMICS, INC.San Diego, CAPhase II2023$2.1M
REVBIO, INC.Lowell, MAPhase II2023$2.1M
VOXIMETRY INCMadison, WIPhase II2023$2M
EARLYDIAGNOSTICS INCLOS ANGELES, CAPhase II2023$2M
Siloam Vision, Inc.Lake Oswego, ORPhase II2023$1.9M
BIOCIRCUIT TECHNOLOGIES INCAtlanta, GAPhase II2023$1.9M
CIVATECH ONCOLOGY, INC.Morrisville, NCPhase II2023$1.9M
Redbud Labs, Inc.Durham, NCPhase II2023$1.8M
REVBIO, INC.Lowell, MAPhase II2023$1.7M
PICCOLO MEDICAL, INC.San Francisco, CAPhase II2023$1.7M
BIVACOR INCHouston, TXPhase II2023$1.6M
SINOPIA BIOSCIENCES INCSan Diego, CAPhase II2023$1.6M
AQUALUNG THERAPEUTICS, CORPJuno Beach, FLPhase II2023$1.5M
OLIGOMERIX INCWhite Plains, NYPhase II2023$1.5M
ACURASTEM INCMonrovia, CAPhase II2023$1.5M
BLACKROCK MICROSYSTEMS, INCSalt Lake City, UTPhase II2023$1.5M
LINSHOM MEDICAL INCEllicott City, MDPhase II2023$1.5M
SPINOGENIX, INC.San Diego, CAPhase II2023$1.4M
ACURASTEM INCMonrovia, CAPhase II2023$1.4M
ATLASXOMICS INCNew Haven, CTPhase II2023$1.4M
Spark Neuro Inc.New York, NYPhase II2023$1.3M
MODULATION THERAPEUTICS, INC.Morgantown, WVPhase II2023$1.3M
CARE.COACH CORPORATIONMillbrae, CAPhase II2023$1.3M
PRENOSIS INCChampaign, ILPhase II2023$1.3M
Neuroptics, Inc.Irvine, CAPhase II2023$1.3M
REVBIO, INC.Lowell, MAPhase II2023$1.3M
IMMUNOPHOTONICS INCSaint Louis, MOPhase II2023$1.2M
SAROS THERAPEUTICS INCRiverwoods, ILPhase II2023$1.2M

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are non-dilutive — the agency takes no equity.

Instruments
Grants
Tracked investments
2639
Unicorns
6
IPOs
42
Acquisitions
26

Founder mafia

2 people who came through National Institutes of Health (NIH) went on to found or lead other companies.

What they invest in

from 1842 of 2639 portfolio companies

Biotech ×1112Healthtech ×1032Medical Devices ×815Deep Tech ×617Digital Health ×390AI & Machine Learning ×354Hardware ×332New Materials ×117

HQs:United States×1278United Kingdom×3Canada×1Germany×1Spain×1Indonesia×1

Investments · showing 1200 of 2639

founders shown can be your intro path

By year:2023 · 1532022 · 1952021 · 1982020 · 1722019 · 2552018 · 2542017 · 2682016 · 3052015 · 3572014 · 1862013 · 362012 · 32388 dated

Achieve Life Sciencesachievelifesciences.comin𝕏NASDAQ: ACHVAug 2021 · $2.8M

Achieve is a specialty pharmaceutical company developing and commercializing cytisinicline as a treatment for nicotine dependence, aimed at helping people who smoke quit.

BiotechHealthtechVancouver, B.C., US

Anthony Clarke(Executive Officer)Richard Stewart(Co-founder & Director (former President and CEO))Cindy Jacobs(Executive Officer, Director)inJaime Xinos(Executive Officer)inJohn Bencich(Executive Officer, Director)inAndrew D. Goldberg(Chief Executive Officer & Director)in

Co-investorsLifeSci Venture PartnersvenBio PartnersVivo CapitalFrazier Life Sciences

Aethlon Medicalaethlonmedical.cominNASDAQ: AEMDSep 2018 · $2.5M

Aethlon Medical develops the Hemopurifier, a clinical-stage extracorporeal device that uses lectin-based technology to remove extracellular vesicles and enveloped viruses from blood plasma, with current clinical programs targeting patients with advanced cancer resistant to immunotherapy and potential applications in life-threatening viral infections.

BiotechSan Diego, US

Richard H. Tullis(Executive Officer, Director)James B. Frakes(Executive Officer, Director)Rodney S. Kenley(Executive Officer, Director)James Joyce(Executive Officer, Director)inSteven P. LaRosa(Chief Medical Officer)inRICHARD H. TULLIS, PhD(Executive Officer)

Agenusagenusbio.comNASDAQ: AGENSep 2016 · $1.3M

Agenus is a biotechnology company developing cancer immunotherapies, including its lead investigational combination of botensilimab (an anti-CTLA-4 antibody) and balstilimab (a PD-1 inhibitor), known as BOT+BAL.

BiotechHealthtechLexington, US

Garo Armen(Chairman & CEO, Co-founder)Ozer Baysal(Executive Officer)Robert Stein(Executive Officer)Christine Klaskin(Executive Officer)inKaren Valentine(Executive Officer)Steven O'Day(Chief Medical Officer)in

Co-investorsAdvent Life SciencesGrazia Equity GmbHHEALTHCARE ROYALTY PARTNERSOberland CapitalCommodore CapitalInvus+2 more

Alto Neurosciencealtoneuroscience.comin𝕏NYSE: ANROMar 2020 · $3.2M

Alto Neuroscience is a clinical-stage biopharmaceutical company developing biology-driven medicines for neuropsychiatric conditions, using measurements of brain biology to predict clinical response and identify patients likely to benefit from its drug candidates.

BiotechDigital HealthMental HealthMountain View, US

Amit Etkin(Founder)inAdam Savitz(Executive Officer)inMichael Hanley(Executive Officer)Nicholas Smith(Chief Financial Officer and Chief Business Officer)inAaron Weaver(Director)Po Yu (Jeff) Chen(Director)

Co-investorsAble PartnersAlpha Wave GlobalInVivium CapitalK2 HealthVenturesKorify CapitalMana Ventures+12 more

Arcadia Biosciencesarcadiabio.cominNASDAQ: RKDAMar 2015 · $3.9M

Arcadia Biosciences develops specialty wheat ingredients with enhanced nutritional profiles — such as higher fiber, improved protein, reduced gluten, and longer shelf life — working with food manufacturers and processors to reformulate wheat-based products.

AgTechBiotechFoodTechDallas, US

Thomas J. Schaefer(Executive Officer, Director)Matthew T Plavan(Executive Officer)Rajendra Ketkar(Executive Officer, Director)inEric J. Rey(Executive Officer, Director)inMark Wong(Director)James Reis(Director)

Co-investorsSaints Capital

Arvinas Holding Co. LLCarvinas.comin𝕏NASDAQ: ARVNApr 2016 · $1.1M

Arvinas is a biopharmaceutical company developing PROTAC protein degrader therapies, with a pipeline focused on oncology and neurology.

BiotechHealthtechNew Haven, US

Sean Cassidy(Executive Officer)inManuel Litchman(Executive Officer, Director)inRandy Teel(President and Chief Executive Officer; Director)inCraig Crews(Founder)

BoardStephen Squinto(Director)inLiam Ratcliffe(Director)in

Co-investors5AM VenturesAccess BiotechnologyCanaan PartnersConnecticut InnovationsNextech InvestRA Capital+3 more

Azitraazitrainc.comNYSE: AZTRAug 2016 · $375K

Azitra is a clinical-stage biopharmaceutical company developing genetically engineered bacteria and proteins for treating skin diseases through precision dermatology.

AI & Machine LearningBiotechHealthtechFarmington, US

Francisco D. Salva(President and Chief Executive Officer)inAzim Munivar(Executive Officer, Director, Promoter)

BoardStella Robertson(Director)inTravis Whitfill(Executive Officer, Director, Promoter)in

Co-investorsBios PartnersConnecticut InnovationsKdT VenturesLeaps by Bayer

Beta Bionics, Incbetabionics.cominNASDAQ: BBNXSep 2018 · $2M

Beta Bionics develops the iLet Bionic Pancreas System, an insulin delivery device for people with type 1 diabetes aged 6 and older that requires a physician's prescription.

Digital HealthHealthtechMedical DevicesIrvine, US

Edward Damiano(Executive Officer, Director)Sean Saint(President, Chief Executive Officer and Director)inStephen Feider(Chief Financial Officer)inMike Mensinger(Chief Product Officer)inSteven Russell(Chief Medical Officer)inMark Hopman(Chief Commercial Officer)in

Co-investorsLifeSci Venture PartnersWellington ManagementOmega FundsRTW Investments L.P.Soleus Capital

BillionToOnebilliontoone.comin𝕏NASDAQ: BLLNSep 2018 · $224.2K

BillionToOne is a precision diagnostics company that uses molecular counting technology to develop non-invasive prenatal screening and liquid biopsy tests for early disease detection.

BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US

Oguzhan Atay(Founder)inDavid Tsao(CTO)inSukrit Silas(Founder)inBrett Huff(Director of Engineering)Mihir Sewak(Software Engineering Manager)Jen Katzburg(Principal Recruiter)

Co-investors500 Emerging Europe500 GlobalAsymmetry VenturesCivilization Ventures Management, Llce2vcFifty Years+24 more

BioRestorative Therapiesbiorestorative.comNASDAQ: BRTXSep 2021 · $513.2K

BioRestorative Therapies develops cell- and tissue-based therapeutic products, primarily using adult stem cells, targeting conditions such as degenerative disc disease and metabolic disorders.

BiotechHealthtechLongevityMelville, US

Mark Weinreb(Chief Executive Officer, Chairman of the Board and President)Robert Kristal(Executive Officer)Francisco Silva(Director, Executive Officer)Lance Alstodt(Director, Executive Officer)inEdward L. Field(President, Disc/Spine Division)Mandy Clyde(Vice President of Operations and Secretary)

Capricor Therapeuticscapricor.comin𝕏NASDAQ: CAPRSep 2013 · $8.4M

Capricor Therapeutics is a biotechnology company developing allogeneic cardiosphere-derived cell (CDC) and exosome-based therapeutics to treat serious diseases including Duchenne muscular dystrophy.

BiotechMedical DevicesLos Angeles, US

Linda Marban(President and Chief Executive Officer, Director)inLinda Marbán, Ph.D.(Chief Executive Officer and Director; co-founder of Capricor, Inc.)Rachel Smith(Executive Officer)inKaren Krasney(Executive Officer)inAnthony Bergmann(Executive Officer)Andrew Hamer(Executive Officer)in

Co-investorsBroadview Ventures

Cartesian Therapeutics (NASDAQ: RNAC)cartesiantherapeutics.comin𝕏NASDAQ: RNACAug 2018 · $6.3M

Cartesian Therapeutics is a clinical-stage biotechnology company developing mRNA-based cell therapies aimed at treating autoimmune diseases.

BiotechHealthtechWatertown, US

Metin Kurtoglu(Executive Officer)Omid Farokhzad(Director)Chris Jewell(Executive Officer)inCarsten Brunn(President, CEO & Chairman of the Board)inEmily English(Executive Officer)inBlaine Davis(Executive Officer)in

Co-investorsK2 HealthVenturesMaryland TEDCOSchooner CapitalTEDCO+ND CapitalPolaris Partners+1 more

CEL SCIcel-sci.comin𝕏NYSE: CVMSep 2017 · $2.5M

CEL-SCI Corporation is a biotech company developing immunotherapies, particularly Multikine, which is advancing through FDA regulatory processes.

BiotechHealthtechMedical DevicesVienna, US

Patricia B. Prichep(Executive Officer)Eyal Talor(Executive Officer)inGeert R. Kersten(Chief Executive Officer)inDaniel H. Zimmerman(Executive Officer)inJohn Cipriano(Executive Officer)in

BoardPeter Young(Director)

Cellectar Biosciencescellectar.comin𝕏NASDAQ: CLRBSep 2021 · $6.1M

Cellectar Biosciences is a clinical-stage oncology company developing targeted cancer therapies using its proprietary PLE (phospholipid ether) delivery platform, which delivers therapeutic payloads directly to cancer cells.

BiotechHealthtechMadison, US

Jamey P. Weichert(Executive Officer, Director)inJohn E. Friend II(Executive Officer)James V. Caruso(Executive Officer, Director)Jarrod Longcor(Executive Officer)inSimon Pedder(Executive Officer, Director)inChad J. Kolean(Executive Officer)in

Champions Oncologychampionsoncology.comin𝕏NASDAQ: CSBRMar 2015 · $2M

Champions Oncology offers a KRAS-focused preclinical platform built on patient-derived xenograft (PDX) models screened with the pan-RAS(ON) inhibitor daraxonrasib, combining in vivo pharmacology with multi-omic characterization to study drug response and resistance.

AI & Machine LearningBiotechHealthtechHackensack, US

Ronnie Morris(Executive Officer, Director)inJames McGorry(Executive Officer)David Miller(Chief Financial Officer)inJoel Ackerman(Executive Officer, Director)inRob Brainin(Chief Executive Officer)inMaria Mancini(Chief Operating Officer)in

Co-investorsBattery VenturesNew Enterprise Associates (NEA)Israel Biotech Fund

Collegium Pharmaceuticalcollegiumpharma.comin𝕏NASDAQ: COLL

Collegium Pharmaceutical is a biopharmaceutical company developing a portfolio of medications to treat serious medical conditions.

BiotechCanton, US

Michael Heffernan(Executive Officer, Director)inPaul Brannelly(Executive Officer)inVikram Karnani(President and Chief Executive Officer, and Director)in

BoardEran Nadav(Director)John Freund(Director)Patrick Heron(Director)in

Co-investorsAPERTURE Venture PartnersEcoR1 CapitalFrazier Life SciencesLongitude CapitalBoston Millennia PartnersRA Capital

Context Therapeuticscontexttherapeutics.comin𝕏NASDAQ: CNTXSep 2016 · $225.2K

Context Therapeutics develops clinical-stage T cell engaging bispecific antibody therapies for the treatment of solid tumors.

BiotechHealthtechPhiladelphia, US

Martin Lehr(Founder)inJennifer Minai-Azary(Executive Officer)inAlex Levit(Executive Officer)Linda Beth West(Director)Richard Jay Berman(Director)Philip Kantoff(Director)in

Co-investorsNextech InvestOUP (Osage University Partners)Torrey Pines Investment

Crinetics Pharmaceuticalscrinetics.comin𝕏NASDAQ: CRNXFeb 2015 · $10.3M

Crinetics is a pharmaceutical company focused on discovering, developing, and commercializing therapies for endocrine diseases and endocrine-related conditions.

BiotechSan Diego, US

Richard Scott Struthers(Executive Officer, Director)Stephen Betz(Chief Scientific Officer)inR. Scott Struthers(President, Chief Executive Officer and Director)inTobin Schilke(Chief Financial Officer)inIsabel Kalofonos(Chief Commercial Officer)inYunFei Zhu(Executive Officer)

Co-investors5AM VenturesForesite CapitalOrbiMedRA CapitalVivo Capital

Editas Medicineeditasmedicine.comin𝕏NASDAQ: EDITJul 2015 · $225K

Editas Medicine develops gene editing medicines using CRISPR/Cas9 and CRISPR/Cas12a technology to treat serious diseases including blood disorders, cardiovascular conditions, and cancer.

BiotechDeep TechMedical DevicesCambridge, US

Feng Zhang(Founder)inGeorge Church(Scientific Founder, Professor of Genetics, Harvard University and MIT)inKeith Joung(Scientific Founder, Professor of Pathology, Harvard Medical School)inDavid Liu(Scientific Founder, Professor of Chemistry and Chemical Biology, Harvard University)inKatrine Bosley(Executive Officer, Director)inVic Myer(Executive Officer)in

Co-investorsEcoR1 CapitalGV (Google Ventures)Sofinnova VenturesViking GlobalAtlas VentureDeerfield Management Company+3 more

FibroBiologicsfibrobiologics.cominNASDAQ: FBLGSep 2021 · $551.3K

FibroBiologics develops fibroblast cell-based therapies for chronic and degenerative conditions, targeting areas such as multiple sclerosis and other autoimmune diseases, degenerative disc disease, wound healing, and age-related organ decline (thymus and spleen).

BiotechHealthtechLongevityHouston, US

Pete O'Heeron(Chairman, Founder and Chief Executive Officer)inJason D. Davis(Chief Financial Officer)inRuben A. Garcia(General Counsel)inHamid Khoja(Chief Scientific Officer)

BoardStacy Coen(Director)Matthew Link(Director)

Ginkgo Bioworksginkgo.bioin𝕏NYSE: DNA

Ginkgo Bioworks builds autonomous labs that accelerate bioengineering for applications in pharmaceutical, agricultural, and industrial biotechnology.

AgTechAI & Machine LearningBiotechDeep TechHealthtechRoboticsBoston, US

Jason Kelly(Founder)inReshma Shetty(Founder)inBarry Canton(Founder)inAustin Che(Founder)inTom Knight(Founder)inBartholomew Canton(Executive Officer)

Co-investors11.2 CapitalAllen Institute for AI (AI2) IncubatorAzure Capital PartnersB3 HoldingBlue Owl CapitalCannage Capital+63 more

Inmune Bioinmunebio.comin𝕏NASDAQ: INMBSep 2020 · $2M

INmune Bio is a clinical-stage biotechnology company developing immunotherapies, including XPro1595, aimed at treating neurodegenerative and psychiatric diseases through a biomarker-directed approach.

BiotechDigital HealthHealthtechLa Jolla, US

Mark Lowdell(CSO/CMO)inRaymond Tesi(Chief Executive Officer)David J. Moss(CEO)inJ. Kelly Ganjei(Director)Terry R. Knapp(Director)

Jupiter Orphan Therapeuticsjupiterorphan.comNASDAQ: JUNSSep 2020 · $2M

Jupiter Neurosciences develops JOTROL, an enhanced resveratrol formulation designed to address neuroinflammatory and central nervous system disorders, with a Phase IIa trial underway in Parkinson's Disease, while also selling wellness supplements under the Nugevia brand through direct-to-consumer channels.

HealthtechJupiter, US

Jacob Uittenbogaard(Chief Financial Officer, Treasurer and Secretary)inMarshall Hayward(Chief Scientific Officer)Christer Rosén(Chief Executive Officer and President)inSaleem Elmasri(Chief Financial Officer)Alexander Rosén(Chief Administrative Officer)inAlison D. Silva(President and Chief Operating Officer, and Director)

Co-investorsTarnagulla Ventures

KALA BIOkalarx.cominNASDAQ: KALA

A biopharmaceutical company developing an artificial intelligence infrastructure platform designed for on-premises deployment in biotechnology and pharmaceutical research environments, serving biotech firms and pharma companies seeking secure access to advanced AI capabilities while retaining control over proprietary biological data; the company is also evaluating strategic alternatives for its legacy mesenchymal stem cell secretome assets after discontinuing its lead rare eye disease therapeutic program.

BiotechArlington, US

Justin Hanes(Director)inKevin Pojasek(Executive Officer)inDarius Kharabi(Executive Officer)inTodd Bazemore(Executive Officer)inMark Iwicki(Executive Officer, Director)inMary Reumuth(Executive Officer)in

Co-investorsLongitude CapitalSR One Capital ManagementWellington ManagementYsios CapitalAtlas VentureLux Capital+2 more

Marker Therapeuticsmarkertherapeutics.cominNASDAQ: MRKRAug 2023 · $664.8K

Marker Therapeutics develops novel T cell therapies, including adoptive T cell therapy approaches, for clinical applications in oncology and other diseases with high unmet need.

BiotechHealthtechHouston, US

Juan Vera(Executive Officer, Director)inDr. Vera(Co-founder)Glynn Wilson(Executive Officer, Director)John Bonfiglio(Executive Officer, Director)

BoardSteven Elms(Director)inJohn Wilson(Director)

Co-investorsAisling CapitalNew Enterprise Associates (NEA)

MicroTranspondermicrotransponder.com𝕏NASDAQ: MOBIFeb 2016 · $8.1M

Mobia Medical (formerly MicroTransponder) develops Vivistim Paired VNS Therapy, an FDA-approved treatment for stroke survivors with moderate to severe upper extremity impairment.

Digital HealthHealthtechMedical DevicesAustin, US

Richard John Foust(Executive Officer, Director)Frank McEachern(Executive Officer, Director)in

BoardNelson Bunker Curnes(Executive Officer, Director)Thomas Jordan Curnes II(Executive Officer, Director)Casey Tansey(Director)Dana Mead(Director)

Co-investorsLongitude CapitalUT Horizon FundGreen Park & Golf VenturesUS Venture Partners

Myomomyomo.comin𝕏NYSE: MYO

Myomo develops wearable robotic orthoses to restore arm and hand function for individuals with limited mobility due to stroke, brachial plexus injury, or spinal cord injury.

HardwareHealthtechMedical DevicesRoboticsCambridge, US

Paul R. Gudonis(Chairman & Chief Executive Officer)inSteve Kelly(Executive Officer, Director)

BoardThomas Kirk(Director)Byron Smith(Director)Thomas A. Crowley, Jr.(Director)

Co-investorsBoston Harbor Angels

Omada Healthomadahealth.comin𝕏NASDAQ: OMDAJul 2015 · $195.7K

Omada Health provides virtual-first, integrated care programs for chronic disease management, delivered as data-driven solutions for employers, health plans, and healthcare organizations.

Digital HealthHealthtechWellness & FitnessSan Francisco, US

Andrew DiMichelle(Executive Officer, Director)Adrian James(Founder)inSean Duffy(Founder)inWei-Li Shao(President)inSteve Cook(Chief Financial Officer)inAndrew DiMichele(Founder)

Co-investorsaMoonAndreessen HorowitzBlackbird VenturesCanvas VenturesCivilization Ventures Management, LlcDesigner Fund+19 more

Oragenicsoragenics.cominNYSE: OGENAug 2021 · $456.7K

Oragenics develops treatments for concussion and traumatic brain injury, focusing on clinical development of therapeutic candidates.

BiotechDeep TechDigital HealthLongevityMedical DevicesTampa, US

Alan Joslyn(Executive Officer, Director)inMichael Sullivan(Executive Officer)Janet Huffman(Chief Executive Officer & Chief Financial Officer)James P. Kelly(Chief Medical Officer)William Peacock(Chief Clinical Officer)

BoardRobert Koski(Director)

PDS Biotechnology Corp.pdsbiotech.comin𝕏NASDAQ: PDSB

PDS Biotech develops T cell activating immunotherapies for cancer and infectious disease vaccines in clinical stages.

BiotechHealthtechNorth Brunswick, US

Frank K. Bedu-Addo(Executive Officer)inFrank Bedu-Addo(President, Chief Executive Officer, Principal Executive Officer and Director)inGregory L. Conn(Chief Scientific Officer)Kirk Shepard(Chief Medical Officer)inLars Boesgaard(Chief Financial Officer, Principal Financial Officer and Principal Accounting Officer)inStephan Toutain(Chief Operating Officer)in

Co-investorsElevate VenturesEMV CapitalYorkville Advisors

Protagonist Therapeuticsprotagonist-inc.comin𝕏NASDAQ: PTGXSep 2015 · $3.2M

Protagonist is a company that emphasizes a diverse and inclusive corporate culture as central to its innovation, with stated goals of creating wins for its organization and for patients.

BiotechHealthtechMilpitas, US

Dinesh V. Patel, PhD(Executive Officer, Director)Dinesh Patel(President & Chief Executive Officer)

BoardAsish K. Xavier, Ph.D.(Director)Michael Panaccio, Ph.D.(Director)Armen Shanafelt, Ph.D.(Director)Paul F. Truex(Director)

Co-investorsAisling CapitalCanaan PartnersJJDCJohnson & Johnson Innovation – JJDCLilly VenturesRA Capital+1 more

Recursion Pharmaceuticalsrecursion.comin𝕏NASDAQ: RXRXMar 2015 · $3.5M

Recursion applies computational and data-driven approaches to biological science, aiming to accelerate drug discovery and develop new treatments.

AI & Machine LearningBiotechData & InfrastructureDeep TechMedical DevicesSalt Lake City, US

Chris Gibson(Co-founder and Chairman of the Board)inBlake C. Borgeson(Executive Officer, Director)inDean Y. Yi(Executive Officer, Director)Najat Khan(Chief Executive Officer)inNajat Khan, Ph.D.(CEO and President)inBlake Borgeson(Founder)

Co-investorsDCVC (Data Collective)Lux CapitalBaillie GiffordAdvantage Capital PartnersAir Street CapitalAmplify Partners+23 more

Sabsab.bioin𝕏NASDAQ: SABSAug 2016 · $3M

SAB BIO is a clinical-stage biopharmaceutical company developing multi-specific human immunoglobulin G (hIgG) therapies to treat and prevent immune and autoimmune disorders, using genetically engineered transchromosomic cattle to produce therapeutic candidates.

BiotechDigital HealthHealthtechMedical DevicesMiami Beach, US

Eddie J Sullivan(Founder)inRussell Beyer(Executive Officer)inSamuel J. Reich(Class III Director, Chief Executive Officer)in

BoardJeffrey Spragens(Director)Andrew Moin(Director)Jay Skyler(Director)

Co-investorsJDRF T1D Fund

Savarasavarapharma.cominNASDAQ: SVRAMar 2013 · $4.5M

Savara is a biopharmaceutical company developing treatments for autoimmune pulmonary alveolar proteinosis (autoimmune PAP) and other rare lung diseases.

BiotechHealthtechMedical DevicesAustin, US

Matt Pauls(Chair of the Board of Directors and Chief Executive Officer)inMike Ciesla(Executive Officer)Badrul Chowdhury(Executive Officer)inSantosh J. Vetticaden(Executive Officer)Gregory D. Gorgas(Executive Officer)Patrick Keran(Executive Officer)

Co-investorsBain Capital Life SciencesCentral Texas Angel NetworkGreen Park & Golf VenturesKeiretsu ForumMoore Venture PartnersNew Enterprise Associates (NEA)

Scynexisscynexis.comin𝕏NASDAQ: SCYXDec 2014 · $448.3K

SCYNEXIS develops fungerp-based antifungal therapies, including SCY-247, for treating and preventing severe, progressive, and often fatal fungal diseases and antimicrobial-resistant infections.

BiotechDurham, US

Yves J. Ribeill(Executive Officer, Director)inCharles F. Osborne, Jr.(Executive Officer)Brian Schwab(Executive Officer)inDavid Angulo(Chief Executive Officer, President and Director)in

BoardLaurent Arthaud(Director)Mounia Chaoui(Director)

Co-investorsDecheng CapitalForesite CapitalDeerfield Management CompanyRA Capital

Seerseer.bioinNASDAQ: SEERSep 2019 · $2M

Seer develops proteomics tools for large-scale protein analysis, including an assay, automation instrument, and analysis software for studying the proteome across human and non-human samples.

BiotechDeep TechHardwareHealthtechBoston, US

Omid Farokhzad(Founder)inPhilip Ma(Executive Officer)Shadi Aryanpour(Executive Officer)David Singer(Director)Omid Cameron Farokhzad(Founder)in

BoardTerrance McGuire(Director)

Co-investorsSoftBank Vision FundSolasta VenturesWingaMoonMaverick VenturesPolaris Partners+1 more

SenesTechsenestech.comNASDAQ: SNES

SenesTech develops fertility-control products for managing rodent populations, offering an alternative to traditional rodenticides.

AgTechBiotechPhoenix, US

Thomas C. Chesterman(Executive Officer)inJoel L. Fruendt(Chief Executive Officer)inKenneth Siegel(Chief Executive Officer and Director)Michael Edell(Interim Chief Operating Officer)Julie Williams, MD(Director)Marc Dumont(Director)

Senti Biosciencessentibio.comin𝕏NASDAQ: SNTISep 2018 · $2.2M

Senti Bio develops cell and gene therapies for cancer and difficult-to-treat diseases using synthetic biology and engineered Gene Circuits to enhance precision, control, and selectivity in targeting tumor cells.

BiotechDeep TechMedical DevicesSouth San Francisco, US

Tim Lu(Co-Founder and Chief Executive Officer)inPhilip Lee(Executive Officer)inKanya Rajangam(President, Head of Research & Development and Chief Medical Officer)inYvonne Li(Executive Officer)inJames Collins(Director)Timothy Lu(Founder)

Co-investorsEvolution VC PartnersFlucas VenturesGreen Sands EquityLifeforce CapitalLifeSci Venture PartnersLux Capital+13 more

Soligenixsoligenix.comNASDAQ: SNGXSep 2017 · $7.1M

Soligenix is a biopharmaceutical company developing treatments for rare diseases, with programs in photodynamic therapy for cutaneous T-cell lymphoma and psoriasis, immunomodulatory drugs for inflammatory conditions, and vaccine candidates for infectious diseases.

BiotechPrinceton, US

Richard C. Straube, MD MSc(Executive Officer)Karen Krumeich(Executive Officer)Oreola Donini, PhD(Executive Officer)Christopher J. Schaber(Executive Officer, Director)inAdam T. Rumage(Executive Officer)R. Christopher Cavalli, PhD(Executive Officer)

Co-investorsPontifax Venture Capital

SUTROVAX, INC.sutrovax.comNASDAQ: PCVXJul 2016 · $196.1K

Vaxcyte is a biotech company developing vaccines to treat or prevent serious infectious diseases.

BiotechDeep TechHealthtechSouth San Francisco, US

Grant Pickering(Chief Executive Officer, Director and Co-Founder)Jeff Fairman(Vice President of Research and Co-Founder)Ashish Khanna(Executive Officer)

BoardTracy Saxton(Director)William Newell(Director)Kurt von Emster(Director)in

Co-investorsAbingworthCTI Life Sciences Fund L.P.Foresite CapitalFrazier Life SciencesJanus Henderson InvestorsLongitude Capital+5 more

EMMUNE INCemmune.bioJun 2015 · $16.2M✓ verified

Emmune develops synthetic antibodies for HIV treatment and prevention, using engineered proteins that block viral infection pathways.

BiotechDeep TechDigital HealthHealthtechMedical DevicesMiami, US

Dr. Alpert(President & Co-founder)Dr. Michael FarzanDr. Charles BaileyDr. Matthew GardnerDr. Guocai Zhong

InformAIinformai.comin𝕏✓ verified

InformAI develops AI-guided clinical solutions for oncology and diagnostic imaging to improve patient treatment outcomes.

AI & Machine LearningDigital HealthHealthtechMedical DevicesHouston, US

Co-investorsJoyance PartnersSocial StartsDEFTA PartnersJP Morgan Chase

▶︎ STRM.BIOstrm.bioinJul 2022 · $2.1M

STRM.BIO develops technology to deliver gene therapies, aiming to improve how these treatments reach patients.

BiotechDeep TechHealthtechLongevityMedical Devices

Michael Luther(CEO)in

Co-investorsAscension VenturesBreakout LabsBreakout VenturesDelos CapitalNYBC VenturesBoehringer Ingelheim Venture Fund+2 more

149 BIO LLC149bio.comin𝕏Aug 2023 · $306.5K

149 Bio develops integrin-targeted therapies for kidney disease, with a lead program (ONT01) that is a Phase 1/2-stage small molecule integrin αMβ2 (CD11b) agonist for lupus nephritis and focal segmental glomerulosclerosis.

AI & Machine LearningBiotechDeep Tech

19101910.aiin𝕏Jul 2021 · $546.4K

1910 develops an AI platform that integrates multimodal data, frontier AI models, and high-throughput lab automation to accelerate drug discovery and development for pharmaceutical companies.

AI & Machine LearningBiotechDeep TechHealthtechBoston, US

Jen Asher(CEO)inJennifer O. Nwankwo(Executive Officer, Director)Jen Nwankwo(Founder)

BoardSamir Kumar(Director)Marc Foster(Director)Jory Bell(Director)in

Co-investorsFoundersX VenturesPlayground GlobalY CombinatorEmles Venture PartnersJude GomilaM12 (Microsoft's Venture Fund)+6 more

1ST PLAYABLE PRODUCTIONS LLC1stplayable.comin𝕏May 2016 · $375K

1st Playable Productions is a game development studio that creates games for entertainment, education, and other applications while also supporting other developers and partners in game creation.

EdTechGaming

Tobi Saulnier(Founder and CEO)

20/20 GeneSystems2020gene.com

20/20 BioLabs develops laboratory blood tests using machine learning for the early detection of cancers and chronic diseases, including a multi-cancer early detection (MCED) protein tumor marker test and an inflammation biomarker test.

AI & Machine LearningBiotechDigital HealthGaithersburg, US

Jonathan Cohen(President & CEO, founder)inMr. Cohen(Founder, CEO & President)Anne Shiflett(Executive Officer)Jiminy Zhou(Executive Officer)Dr. Lebowitz(Chief Scientific Officer)Mr. Bergman(Chief Financial Officer)

Co-investorsKeiretsu Forum

21st Century Medicine, Inc.21cm.comSep 2018 · $4M

21CM develops advanced biopreservation technologies, including vitrification and cryopreservation solutions, for preserving living systems ranging from mammalian cells to whole organs in biomedical research and clinical applications.

BiotechDeep TechFemTechHealthtechLongevityMedical DevicesFontana, US

Greg Fahy(Chief Scientific Officer)

2B TECHNOLOGIES, INC.twobtech.comAug 2015 · $2.2M
2Morrow2morrowinc.cominMay 2021 · $1.9M

2Morrow provides evidence-based digital wellness programs delivered through a smartphone and web app, using Acceptance and Commitment Therapy principles to help people quit tobacco, manage stress, and change health behaviors.

Digital HealthMental HealthWellness & FitnessKirkland, US

Jo Masterson(Executive Officer, Director)inBrandon Masterson(Executive Officer)in

BoardJohn Koster(Director)Eric Larsen(Director)in

Co-investorsPortland Seed FundAlliance of AngelsWRF Capital

2WITECH SOLUTIONS LLC2witech.comMay 2023 · $173.1K

2Witech Solutions develops sensing products for water monitoring and contamination detection using engineered nanostructures.

CleantechDeep TechNew Materials

3-C INSTITUTE FOR SOCIAL DEVELOPMENT INC3cisd.comAug 2014 · $36.2M

3C Institute builds custom technology and digital health software for researchers, educators, program developers, and clinicians, supporting the development and delivery of research-based programs.

Digital HealthEdTechHealthtech

3D Molecular Designs, LLC3dmoleculardesigns.comin𝕏Apr 2021 · $3.6M

3D Molecular Designs operates SMART Teams, an educational program where students model protein structures using molecular visualization tools and 3D printing to communicate research findings.

BiotechDeep TechEdTechHealthtechMilwaukee, US

Tim Herman(Founder & PhD)Diane Herman(Co-founder & Business Manager)

3DT HOLDINGS, LLC3dtholdings.comApr 2015 · $15.9M
3Helix3helix.com𝕏Apr 2016 · $1.6M

3Helix develops and sells collagen hybridizing peptides (CHP) and related conjugates for research and diagnostic applications.

BiotechHealthtechMedical DevicesNew MaterialsSalt Lake City, US

Mike Kirkness(CEO)inToby Barrack(VP)inMichael Fugman(Director)Michael Yu(Director)Noah Nasser(Director)

BoardNalini D Kelly(Director)

Co-investorsUtah Innovation Fund

3P BIOTECHNOLOGIES, INC.3pbiotechnologies.comSep 2017 · $2.5M

3P Biotechnologies identifies plant-derived bioactive compounds and develops drug delivery systems targeting cancer and chronic disease prevention.

BiotechDeep TechHealthtechLouisville, US

Dr. Gupta(Founder)Al Poskanzer, PhD(Director of Strategic Partnerships)Niti Gupta, BA(Director of Finances & Administration)

3Scan3scan.comSep 2018 · $240.8K

San Francisco, US

Todd Huffman(Founder)Megan Klimen(Founder)

BoardJoshua Wolfe(Director)Matt Ocko(Director)inAdam Goulburn(Director)inAdam Goulborn(Director)

Co-investorsComet LabsDolby Family VenturesRecode VenturesDCVC (Data Collective)Dimension CapitalLux Capital+1 more

490 BIOTECH INC490biotech.comin𝕏Jul 2015 · $4.8M

490 BioTech develops autobioluminescent assay technology that enables cells to produce light autonomously without external luciferin or excitation, allowing continuous, non-destructive monitoring of cellular viability and metabolic activity.

BiotechDeep TechMedical Devices

4e Therapeutics4etherapeutics.comSep 2019 · $7.1M

BiotechAustin, US

Joseph Price(Director)Eric Price(Director)Thomas Craig Benson(Executive Officer, Director)Theodore Price(Director)

5 POINT APP, INC.5pointacupuncture.comSep 2021 · $397.4K

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

ACME EXPRESS, INCActive Signal Technologies, Inc.ADELPHI TECHNOLOGY, LLCADVR, INC.

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CORPHUMMINGBIRD PRECISION MACHINE CO.HUMURINE TECHNOLOGIES, INC.Hunterian MedicineHura ImagingHurdleHydrocisionHydrostasisHYLAPHARM LLCHYPER TECH RESEARCH INCHYPERMELT, LLCHYPNALGESICS, LLCHYPRES INCHYPROTEK, INC.I-FUNCTION, INC.I.S.S (USA), Inc.I3 NirfI3PiIaso TherapeuticsIaterion, Inc.IBC ADVANCED TECHNOLOGIES, INCICBiomeIcellKealex Therapeutics LLCIchor Life Sciences, Inc.IDBiologicsIFYBER LLCIGE THERAPEUTICS, INC.IHEALTHSCREEN INCILLIONIX, LLCImageIQ, Inc.IMAGINE SCIENTIFIC INCImaging Biomarker Solutions Inc.ImaginosticsImago Pharmaceuticals, Inc.Imago Systems, Inc.Imanis Life Sciences, LLCImbed BiosciencesimBioimCare BiotechIMETABOLIC BIOPHARMA CORPIMGGYD LLCIMMERSIVE TECH INCImmPORT Therapeutics Inc dba Antigen Discovery IncImmuDX LLCIMMUNARTES LLCImmune-Onc TherapeuticsIMMUNEXT PHARMACEUTICALSIMMUNO TECHNOLOGIES INCIMMUNOGENICS LLCImmunomic TherapeuticsImmunophotonics, Inc.ImmunoTarget Therapeutics, Inc.ImmusoftImmuto ScientificImmventiontheraIMPACT BUSINESS INFORMATION 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Exits · 68

42 IPOs · 26 acquisitions · showing 41

Achieve Life SciencesNASDAQ: ACHVAethlon MedicalNASDAQ: AEMDAgenusNASDAQ: AGENAlto NeuroscienceNYSE: ANROArcadia BiosciencesNASDAQ: RKDAArvinas Holding Co. LLCNASDAQ: ARVNAzitraNYSE: AZTRBeta Bionics, IncNASDAQ: BBNXBillionToOneNASDAQ: BLLNBioRestorative TherapiesNASDAQ: BRTXCapricor TherapeuticsNASDAQ: CAPRCartesian Therapeutics (NASDAQ: RNAC)NASDAQ: RNACCEL SCINYSE: CVMCellectar BiosciencesNASDAQ: CLRBChampions OncologyNASDAQ: CSBRCollegium PharmaceuticalNASDAQ: COLLContext TherapeuticsNASDAQ: CNTXCrinetics PharmaceuticalsNASDAQ: CRNXEditas MedicineNASDAQ: EDITFibroBiologicsNASDAQ: FBLGGinkgo BioworksNYSE: DNAInmune BioNASDAQ: INMBJupiter Orphan TherapeuticsNASDAQ: JUNSKALA BIONASDAQ: KALAMarker TherapeuticsNASDAQ: MRKRMicroTransponderNASDAQ: MOBIMyomoNYSE: MYOOmada HealthNASDAQ: OMDAOragenicsNYSE: OGENPDS Biotechnology Corp.NASDAQ: PDSBProtagonist TherapeuticsNASDAQ: PTGXRecursion PharmaceuticalsNASDAQ: RXRXSabNASDAQ: SABSSavaraNASDAQ: SVRAScynexisNASDAQ: SCYXSeerNASDAQ: SEERSenesTechNASDAQ: SNESSenti BiosciencesNASDAQ: SNTISoligenixNASDAQ: SNGXSUTROVAX, INC.NASDAQ: PCVXAkoya Biosciencesacq. by Quanterix

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Frequently asked questions

How many investments has National Institutes of Health (NIH) made?
National Institutes of Health (NIH) has 2,639 tracked investments, 68 of which have exited.