/Companies

Alume Biosciences

La Jolla, US · Founded 2017 · Delaware corporation · 17 employees on LinkedIn · 1 known investors

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Alume Biosciences develops nerve illumination technology for surgery, including bevonescein (ALM-488), an injectable peptide that makes nerves glow to help surgeons identify and preserve them during procedures such as head-and-neck and prostate surgery. The drug candidate is in Phase 3 clinical trials, with a planned FDA New Drug Application submission in 2026.

Founders & leadership

Alume Biosciences was founded in 2017 by Quyen Nguyen and Roger Tsien.

QNQuyen Nguyen
Quyen NguyenFounder and CEOQuyen Nguyen is a Professor of Otolaryngology – Head and Neck Surgery at UC San Diego and Co-founder of Alume Biosciences, which develops fluorescent nerve visualization technology for surgery. He has over two decades of experience in healthcare, translational research, and surgical care.
RT
Roger TsienCo-founder
KP
Kaveri ParkerChief Business OfficerExecutive Officer at Synedgen
BBBrett Berman
Brett BermanChief Medical Officerformer
JSJames Schmidt
James SchmidtChief Financial Officer

Board

KK
Kim KamdarBoard director
DBDan Bradbury
Dan BradburyExecutive ChairmanInvestor at BioBrit
JM
Jean-Pierre MillonBoard director
MM
Magda MarquetBoard director

Investors · 1

BioBritlisted by BioBritLa Jolla

How we know: a partner's Signal profile · Not right? Tell us

Funding

SEC filings, press & company announcements

$35.5M disclosed across 6 of 7 rounds · 2019–2026

▶$2.2MraisedMay 2026 · 4 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Kim KamdarDirector
  • Jean-Pierre MillonDirector
  • Kaveri ParkerExecutive Officer
  • Brett BermanExecutive Officer, Director
  • Dan BradburyDirector
  • James SchmidtExecutive Officer
  • Quyen NguyenExecutive Officer, Director
  • Magda MarquetDirector
Offering amount
$8M
Amount sold
$2.2M
Minimum investment
$50K
First sale
Mar 2026
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$6.9MraisedFeb 2026 · 92 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Kim KamdarDirector
  • Kaveri ParkerExecutive Officer
  • Jean-Pierre MillonDirector
  • Brett BermanExecutive Officer, Director
  • James SchmidtExecutive Officer
  • Dan BradburyDirector
  • Quyen NguyenExecutive Officer, Director
  • Magda MarquetDirector
Offering amount
$23.5M
Amount sold
$6.9M
Minimum investment
$25K
Sales commissions
$662.8K
Placement agents
PHX Financial Inc.
First sale
Oct 2025
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$12.8MraisedJan 2023 · 43 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Kim KamdarDirector
  • Jean-Pierre MillonDirector
  • Magda MarquetDirector
  • James SchmidtExecutive Officer
  • Quyen T. NguyenExecutive Officer, Director
  • Dan BradburyDirector
  • Brett BermanExecutive Officer, Director
Offering amount
$45M
Amount sold
$12.8M
Proceeds to insiders
$153.6K
First sale
Dec 2022
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$4MraisedSep 2022 · 26 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Magda MarquetDirector
  • Quyen T. NguyenExecutive Officer, Director
  • Jean-Pierre MillonDirector
  • Dan BradburyDirector
  • Kim KamdarDirector
  • James SchmidtExecutive Officer
  • Brett BermanExecutive Officer, Director
Offering amount
$5.2M
Amount sold
$4M
First sale
Apr 2022
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$4MraisedAug 2020 · 34 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Kim KamdarDirector
  • Magda MarquetDirector
  • Brett BermanExecutive Officer, Director
  • James SchmidtExecutive Officer
  • Dan BradburyDirector
  • Quyen T NguyenExecutive Officer, Director
  • Jean-Pierre MillionDirector
Offering amount
$4M
Amount sold
$4M
First sale
Aug 2020
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$5.8MraisedJul 2019 · 40 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Quyen T NguyenExecutive Officer, Director
  • James SchmidtExecutive Officer
  • Brett BermanExecutive Officer
Offering amount
$8.6M
Amount sold
$5.8M
First sale
Jun 2019
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Related companies · 3

Companies working in the same space as Alume Biosciences.

Non-dilutive funding · 4 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
National Institutes of Health (NIH)National Institutes of HealthPhase II2023$937.2K
National Institutes of Health (NIH)National Institutes of HealthPhase II2022$3.4M
National Institutes of Health (NIH)National Institutes of HealthPhase II2020$2.5M
National Institutes of Health (NIH)National Institutes of HealthPhase I2019$299.9K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

In the news

Frequently asked questions

What does Alume Biosciences do?
Alume Biosciences develops nerve illumination technology for surgery, including bevonescein (ALM-488), an injectable peptide that makes nerves glow to help surgeons identify and preserve them during procedures such as head-and-neck and prostate surgery. The drug candidate is in Phase 3 clinical trials, with a planned FDA New Drug Application submission in 2026.
Who founded Alume Biosciences?
Alume Biosciences was founded by Quyen Nguyen, Roger Tsien in 2017.
Who are Alume Biosciences's investors?
Alume Biosciences's investors include BioBrit.
How much funding has Alume Biosciences raised?
Alume Biosciences has disclosed $35.5M raised across 6 of its 7 known rounds.
Where is Alume Biosciences headquartered?
Alume Biosciences is headquartered in La Jolla, US.