National Institutes of Health (NIH) — 2015 Investments

Champions Oncology offers a KRAS-focused preclinical platform built on patient-derived xenograft (PDX) models screened with the pan-RAS(ON) inhibitor daraxonrasib, combining in vivo pharmacology with multi-omic characterization to study drug response and resistance.

AI & Machine LearningBiotechHealthtechHackensack, US

Ronnie Morris(Executive Officer, Director)inJames McGorry(Executive Officer)DMDavid Miller(Chief Financial Officer)inJoel Ackerman(Executive Officer, Director)inRBRob Brainin(Chief Executive Officer)inMMMaria Mancini(Chief Operating Officer)in

Co-investorsBABattery VenturesNENew Enterprise Associates (NEA)ISIsrael Biotech Fund

Crinetics is a pharmaceutical company focused on discovering, developing, and commercializing therapies for endocrine diseases and endocrine-related conditions.

BiotechSan Diego, US

Richard Scott Struthers(Executive Officer, Director)SBStephen Betz(Chief Scientific Officer)inRSR. Scott Struthers(President, Chief Executive Officer and Director)inTSTobin Schilke(Chief Financial Officer)inIKIsabel Kalofonos(Chief Commercial Officer)inYunFei Zhu(Executive Officer)

Co-investors5A5AM VenturesFOForesite CapitalOROrbiMedRARA CapitalVIVivo Capital

Editas Medicine develops gene editing medicines using CRISPR/Cas9 and CRISPR/Cas12a technology to treat serious diseases including blood disorders, cardiovascular conditions, and cancer.

BiotechDeep TechMedical DevicesCambridge, US

FZFeng Zhang(Founder)inGCGeorge Church(Scientific Founder, Professor of Genetics, Harvard University and MIT)inKeith Joung(Scientific Founder, Professor of Pathology, Harvard Medical School)inDLDavid Liu(Scientific Founder, Professor of Chemistry and Chemical Biology, Harvard University)inKBKatrine Bosley(Executive Officer, Director)inVMVic Myer(Executive Officer)in

Co-investorsECEcoR1 CapitalGVGV (Google Ventures)SOSofinnova VenturesVIViking GlobalATAtlas VentureDEDeerfield Management Company+3 more

Omada Health provides virtual-first, integrated care programs for chronic disease management, delivered as data-driven solutions for employers, health plans, and healthcare organizations.

Digital HealthHealthtechWellness & FitnessSan Francisco, US

Andrew DiMichelle(Executive Officer, Director)Adrian James(Founder)inSDSean Duffy(Founder)inWSWei-Li Shao(President)inSCSteve Cook(Chief Financial Officer)inAndrew DiMichele(Founder)

Co-investorsAMaMoonANAndreessen HorowitzBLBlackbird VenturesCACanvas VenturesCICivilization Ventures Management, LlcDEDesigner Fund+19 more

Protagonist is a company that emphasizes a diverse and inclusive corporate culture as central to its innovation, with stated goals of creating wins for its organization and for patients.

BiotechHealthtechMilpitas, US

Dinesh V. Patel, PhD(Executive Officer, Director)DPDinesh Patel(President & Chief Executive Officer)

BoardAsish K. Xavier, Ph.D.(Director)Michael Panaccio, Ph.D.(Director)Armen Shanafelt, Ph.D.(Director)Paul F. Truex(Director)

Co-investorsAIAisling CapitalCACanaan PartnersJJJJDCJOJohnson & Johnson Innovation – JJDCLILilly VenturesRARA Capital+1 more

Recursion applies computational and data-driven approaches to biological science, aiming to accelerate drug discovery and develop new treatments.

AI & Machine LearningBiotechData & InfrastructureDeep TechMedical DevicesSalt Lake City, US

CGChris Gibson(Co-founder and Chairman of the Board)inBCBlake C. Borgeson(Executive Officer, Director)inDean Y. Yi(Executive Officer, Director)NKNajat Khan(Chief Executive Officer)inNajat Khan, Ph.D.(CEO and President)inBlake Borgeson(Founder)

Co-investorsDCDCVC (Data Collective)LULux CapitalBABaillie GiffordADAdvantage Capital PartnersAIAir Street CapitalAMAmplify Partners+23 more

Emmune develops synthetic antibodies for HIV treatment and prevention, using engineered proteins that block viral infection pathways.

BiotechDeep TechDigital HealthHealthtechMedical DevicesMiami, US

Dr. Alpert(President & Co-founder)Dr. Michael FarzanDr. Charles BaileyDr. Matthew GardnerDr. Guocai Zhong

490 BioTech develops autobioluminescent assay technology that enables cells to produce light autonomously without external luciferin or excitation, allowing continuous, non-destructive monitoring of cellular viability and metabolic activity.

BiotechDeep TechMedical Devices

San Diego, US

BMBradley Messmer(Executive Officer, Director)

BoardNeil Senturia(Director)

Co-investorsBLBlackbird VenturesKEKeshif VenturesVEVertical Venture Partners

BiotechLouisville, US

Ronald Nutt(Director)inThomas E Welch(Executive Officer, Director)Robert A Vincill(Executive Officer)

BoardDennis Dougherty(Director)Bengt Langstrom(Director)

Co-investorsMOMountain Group Capital

HealthtechCarlsbad, US

Theodore DeFrank(Chief Executive Officer and President of Issuer)PYPatrick Yount(Chief Financial Officer of Issuer)inStephanie Liva(Director)August Sick(Director)Mary Janatpour(Director)Tammy Brach(Director)

Advanced MRI Technologies is a research and development company specializing in magnetic resonance imaging (MRI) methods for brain, heart, and cancer studies.

Deep TechHealthtechMedical DevicesSebastopol, US

Aeon Imaging develops medical and scientific imaging technology, using confocal imaging based on the electronic aperture of CMOS sensors.

HardwareHealthtechMedical DevicesBloomington, US

Ann Elsner(Founder)

BiotechCincinnati, US

RSRobert Shalwitz(Executive Officer)JGJoseph Gardner(Founder)inDuane Nash(Director)Kevin Peters(Executive Officer)Steve Pakola(Executive Officer)Ian A.W. Howes(Executive Officer)

Co-investorsCICincyTechSOSofinnova VenturesALAlly Bridge GroupOROrbiMed

AfaSci is a biopharmaceutical company developing small molecule and peptide therapeutics for pain and neurology indications, with a lead candidate (AFA-281) that has completed Phase I trials for chronic pain and epilepsy.

BiotechDeep TechHardwareHealthtechSan Francisco, US

Co-investorsBRBroadview Ventures

HealthtechNashville, US

SWScott Werntz(Executive Officer, Director)GSGary Slagle(Executive Officer, Director)in

BoardDirector Ghertner(Director)Vic Gatto(Director)

Payment processing portal for businesses to accept and manage transactions.

Advanced ManufacturingDeep TechDefense TechFintechHardwareBoston, US

AI Biosciences develops rapid and low-cost molecular diagnostic technologies for point-of-care use with high sensitivity and specificity.

AI & Machine LearningBiotechHealthtechMedical DevicesCollege Station, US

Akston Biosciences develops protein-based therapies for pets to support veterinary care and improve treatment accessibility.

BiotechHealthtechBeverly, US

TCTodd C. Zion(Executive Officer, Director)inJames Herriman(Executive Officer)RDRobyn Davis(Director)Lovick E. Cannon(Director)Thomas M. Lancaster(Executive Officer, Director)

Co-investorsBOBoston Harbor AngelsFOFormation Venture Engineering

Aldatu Biosciences develops diagnostic tests for detecting pathogenic drug resistance, particularly HIV and other infectious diseases, using its PANDAA technology platform.

BiotechDigital HealthHealthtechMedical DevicesCambridge, US

Iain J. Macleod(Co-founder & CEO, Chief Science Officer)Marta Fernández Suárez(Co-founder, CEO and CSO)Raúl Rodriguez(Founder & Partner)Mark Urdea(Founder & Partner)David M. Raiser(Executive Officer, Director)Mike(CBO)

Algomedix develops non-opioid pain management therapies based on TRPA1 drug development, targeting chronic pain indications through a clinical-stage biotechnology approach.

BiotechHealthtechMedical Devices

Dr. Jeffrey Herz, Ph.D.(Founder and CEO)Jeffrey Herz(Founder, Chairman of the Board, President and Chief Executive Officer)

AllCells supplies cryopreserved human blood and bone marrow-derived cell products to research organizations worldwide, with a focus on maintaining product integrity through cold chain logistics and validated shipping protocols.

BiotechHealthtechLogistics & Supply ChainMedical DevicesBoston; San Francisco, US

Amprion offers SAAmplify-αSYN, a clinically validated diagnostic test that detects misfolded (pathological) α-synuclein in cerebrospinal fluid to aid diagnosis of neurodegenerative disorders such as Parkinson's disease, Lewy body dementia, and Alzheimer's.

BiotechDigital HealthMedical Devices

Co-investorsDEDecathlon Capital Partners

Angiocrine Bioscience is a biotechnology company focused on developing therapies, presenting its work under a science-driven mission to cure disease.

BiotechSan Diego, US

John T Lomoro(Chief Financial Officer/Treasurer)inPaul W Finnegan(President/Chief Executive Officer)John R Jaskowiak(Chief Operating Officer/Secretary)Marc Cohen(Director)Jeff Jonas(Director)

BoardDavid Parkinson(Director)

Co-investorsGOGood Growth Capital

ArchieMD develops 3D medical animations and interactive educational platforms for healthcare training and patient education.

Digital HealthEdTechHealthtechMedical DevicesAtlanta, US

Robert Levine(President and Chief Medical Officer)Doug Levine(Chairman)

Arima Genomics develops DNA-based cancer diagnostics that combine genomic sequence with 3D genome structural information (via Hi-C sequencing) to detect fusions, rearrangements, ecDNA, and other structural drivers of cancer.

BiotechHealthtechMedical Devices

SSSid Selvaraj(Founder & Chief Operating Officer)inTWTom Willis(Chief Executive Officer)inASAnthony Schmitt(Senior Vice President, Science)inEDErin Davis(Vice President, Marketing)in

Co-investorsBEBerkeley CatalystILIllumina VenturesPHPhase Two Ventures

Biotechnology company developing blood-brain-barrier-penetrating recombinant protein therapies for CNS disorders; acquired by JCR Pharmaceuticals in 2020.

RBRuben Boado(Founder)in

Co-investorsMIMitsui Global InvestmentBOBoehringer Ingelheim Venture Fund

BiotechConsumerGamingMedia & EntertainmentPrairie Village, US

Frank Nicholas Franano(Executive Officer, Director)F. Nicholas Franano(Manager)Maria Sainz(Director)James M. Schultz(Director)Nathaniel Hagedorn(Director)John Ayres(Executive Officer)

Co-investorsSESerra Ventures

BiotechSpringdale, US

Omid Moghadam(Executive Officer)

Cloudflare provides web performance and security infrastructure solutions, helping websites optimize speed and protect against threats and malicious traffic.

Cloud ComputingCybersecurityHealthtechGroton, US

JDJames D. Lechleiter(Director)William Korinek(Executive Officer, Director)JLJeffrey L. Ives(Director)

Co-investorsBOBoston Harbor AngelsUTUT Horizon FundDEDeepWork Capital

Bat&Cat develops a modern wearable hearing aid using connectivity and deep learning to help hearing-impaired people converse in noisy environments, and builds research instruments (the Portable Hearing Laboratory) for scientists working on hearing aid processing technology.

AI & Machine LearningHardwareMedical DevicesPalo Alto, US

Caleb Bell III(Founder)in

Co-investorsNANat Turner

BellBrook Labs supplies life-science research products and services to laboratories, distributed internationally through regional partners across Europe, Asia, and Oceania.

BiotechDeep TechHealthtechMadison, US

RLRobert Lowery(CSO & Founder)inTPTraci Pretsch(CFO)inJBJustin Brink(President)inDon Kennedy(Director)

Co-investorsWIWisconsin Investment Partners

BioAxone is a regenerative medicine and translational neuroscience company developing treatments for spinal cord injury and neurotrauma.

BiotechHealthtechMedical DevicesMontreal, CA

Pierre Caouette(Chief Operating Officer, co-Founder)Lisa McKerracher(Chief Executive Officer)

BioFluidica is a privately held biotechnology company that develops an automated liquid biopsy platform, LiquidScan, for isolating and analyzing rare cells, extracellular vesicles (exosomes), and cfDNA from blood and plasma samples.

Chapel Hill, US

SSSteven Soper(Director)RMRolf Muller(Chief Executive Officer)in

BoardSam Tetlow(Director)Michael Stocum(Director)

BioKier develops oral products for managing lipids and glucose in type 2 diabetes and cardiometabolic disorders, designed to replicate the metabolic benefits of bariatric surgery through colon-targeted nutrient delivery.

BiotechHealthtechMedical DevicesChapel Hill, US

Jerzy R Szewczyk(Executive Officer, Director)RDRoger D Nolan(Executive Officer, Director)in

BoardJames Farrelly(Director)

Co-investorsBRBroadview VenturesFRFreemind Investments

BiotechRockville, US

Jerry Parrott(Executive Officer, Director)in

BoardGlenn Miller(Director)Scott Allocco(Director)Katarzyna Kusmierz(Director)Douglas Clark(Director)Jack Davis(Director)

Co-investorsFRFreemind InvestmentsABAbell Foundation, Inc.

Biomedical Development Corporation develops and commercializes medical technologies from laboratory stage through regulatory approval and market entry.

BiotechConsumerDeep TechDigital HealthHealthtechMedical Devices

The page presents content related to ATTO-TEC fluorescence dyes and consumables used for microscopy imaging applications.

BiotechMedical Devices

BioSensics develops wearable sensors and digital platforms for collecting digital biomarkers, patient monitoring, and outcome assessment in healthcare.

BiotechDeep TechDigital HealthHealthtechIoTMedical DevicesNewton, US

Boston Cell Standards develops calibration and quality-control products (IHCalibrators and IHControls) for immunohistochemistry (IHC) laboratories, used for assay validation, instrument alignment, troubleshooting, and proficiency testing.

BiotechHealthtechMedical DevicesBoston, US

SBSteve Bogen MD PhD(Founder)inKodela Vani, MS(Vice President and Co-Founder, Manufacturing)SSSeshi Sompuram(Co-Founder)in

Co-investorsBABantam Group

BrightOutcome develops digital health research platforms and evidence-based wellness programs for researchers, clinicians, and consumers.

AI & Machine LearningDigital HealthEdTechHealthtechSaaSWellness & Fitness

Niina Haas(Co-President)DerShung Yang(Co-President)

Bruin Biometrics develops biology-based pressure injury detection technology that enables clinicians to identify sub-clinical tissue damage days before visible signs appear.

AI & Machine LearningDigital HealthHealthtechMedical Devices

Cancer Targeted Technology develops small molecule drugs that target Prostate-Specific Membrane Antigen (PSMA) on cancer cells, initially for prostate cancer but with potential for other solid tumors.

BiotechDigital HealthMedical DevicesSan Francisco, US

Clifford Berkman(Founder and Director)John Dugan(Founder and Director)Beatrice Langton-Webster(Chief Executive Officer and Director)

Canget BioTekpharma is a biotech and biopharma company, spun off in 2012 from Roswell Park Cancer Institute, that develops cancer-targeting anticancer agents (including the drug candidate FL118) designed for low toxicity to normal tissue and high efficacy against cancer.

BiotechHealthtechBuffalo, US

Fengzhi Li

Carterra designs and manufactures flexible microfluidic manufacturing systems for the life sciences and biotech research markets.

BiotechDeep TechMedical DevicesNew MaterialsSan Diego, US

Mr. Eckman(Founder)

Co-investorsPAPasadena AngelsTETelegraph Hill Partners

The page is an online gambling/gaming platform (branded "LUXURY333") promoting casino-style games, togel/toto betting, bonuses, and 24-hour customer support.

BiotechSan Diego, US

DSDavid Schwartz(Executive Officer)

Co-investorsFOFormation Venture Engineering

Cellecta develops CRISPR, RNAi, and cell engineering tools and services for genetic screening and cell analysis in research and therapeutic development.

AI & Machine LearningBiotechDeep TechHealthtech

Co-investorsCLCLI Ventures

BiotechPittsburgh, US

Michael Hoerres(Executive Officer, Director)

BoardJames Peters(Director)Steve Grenfell(Director)Paul Schmitt(Director)Noel Doheny(Director)

Co-investorsILIllumina VenturesBEBen Franklin Technology Partners of Northeastern PennsylvaniaPIPittsburgh Life Sciences Greenhouse

Charles River Analytics conducts research and develops AI-driven intelligent systems for defense, cybersecurity, space, and healthcare applications, serving the U.S.

AI & Machine LearningCybersecurityDefense TechRobotics

ChemRegen is a regenerative medicine research and development company that combines stem cell biology with drug development to discover pre-clinical drug candidates.

BiotechDeep TechLongevitySan Diego, US

John Cashman(Chief Operating Officer)

HealthtechHayward, US

GDGUY DIPIERRO(Director)inALAN LEVY, PH.D.(Executive Officer, Director)ANTHONY RIMAC(Executive Officer)ALAN LEVY(Executive Officer, Director)

BoardELIZABETH ROCKETT(Director)WHWENDE HUTTON(Director)in

Co-investorsCOCota CapitalEMEmergent Medical Partners, LLPFOFountain Healthcare PartnersKAKaiser Permanente VenturesMIMission Bay Capital5A5AM Ventures+3 more

Ciencia develops the Centinela platform, an optical diagnostics system for performing scientific assays at lower cost than traditional methods, serving academic researchers and clinical diagnostics applications.

BiotechDigital HealthMedical Devices

Clear Guide Medical develops image-guidance technology, including the Clear Guide SCENERGY system, that provides precision targeting for ultrasound-guided invasive procedures while reducing the need for intermediate imaging.

HardwareHealthtechMedical DevicesBaltimore, US

PHILIPP JAKOB STOLKA(Executive Officer, Director, Promoter)Dorothee Heisenerg(Executive Officer, Director, Promoter)DOROTHEE HEISENBERG(Executive Officer, Director, Promoter)

BoardJames J Condon(Director, Promoter)Paul Clark(Director, Promoter)

Cofactor Genomics develops predictive diagnostics for cancer immunotherapy using RNA-expression models to characterize tumor microenvironments and predict patient response.

AI & Machine LearningBiotechHealthtechMedical DevicesSt. Louis, US

DMDave Messina(COO)inJGJarret Glasscock(CTO)inJarret Glassock(Executive Officer, Director)JAJon Armstrong(COO)inJonathan Wald(Software Engineering Intern)

BoardMAMatthew A. Ocko(Director)in

Co-investorsARArgonautic VenturesASAscension VenturesDCDCVC (Data Collective)FIFifty YearsISiSelect FundJUJude Gomila+12 more

COG provides infrastructure and administrative support for research and technology development, fostering a collaborative environment where scientists can pursue their work with freedom and access to professional development resources.

AI & Machine LearningDeep TechDigital HealthHealthtechImpact & Social GoodPotomac, US

Cognition Therapeutics is a clinical-stage biotechnology company developing zervimesine (CT1812), an investigational once-daily oral small-molecule therapy designed to protect brain synapses by blocking toxic protein oligomers.

BiotechHealthtechPittsburgh, US

SCSusan Catalano(Executive Officer, Director)inSusan Catalano, Ph.D.(Co-founder)LRLisa Ricciardi(Chief Executive Officer)inHarold Safferstein(Executive Officer, Director)

BoardNada Jain(Director)Franz Hefti(Director)

Co-investors3E3E Bioventures CapitalARArieal Southeast Angel PartnersATAtlanta Technology AngelsCOCowtown AngelsDODolby Family VenturesGOGolden Seeds+2 more

CTA is an information technology engineering firm that provides systems services and advanced technology solutions to government and commercial clients for mission-critical operations, with expertise in complex data challenges.

AI & Machine LearningData & InfrastructureEnterprise SoftwareGovTech

CHI (Connecting Health Innovations) develops diagnostic products and counseling services based on its patented Dietary Inflammatory Index (DII) to help individuals and the medical community reduce diet-induced inflammation.

Digital HealthFoodTechWellness & Fitness

James Hébert(Founder / Inventor of the Dietary Inflammatory Index)

Coridea invests in and develops healthcare companies focused on patient-centric solutions.

HealthtechMedical Devices

MGMark Gelfand(Managing Partner and Chief Technical Officer)inHRHoward R. Levin(Managing Partner, President, and Chief Medical Officer)inZEZoar Engelman(Partner and Chief Scientific Officer)inARAdam Rosenwach(Partner and Chief Business Officer)in

Co-investorsBRBroadview VenturesSTStar51 Capital

Co-investorsSISilicon Valley

Crosslife Tech develops diagnostic assay technologies for rapid detection of infectious diseases and genetic conditions.

BiotechHealthtechMedical Devices

HyunDae Cho(President, CEO)

CryoCrate develops cryopreservation solutions for cells and tissues in biomedical research and clinical applications, particularly for cell and tissue types that cannot be preserved or lose viability using existing storage methods.

BiotechDeep TechDigital HealthMedical DevicesNew MaterialsColumbia, US

Dr. Xu Han(President and Chief Technology Officer)

Co-investorsCECentennial Investors

Co-investorsNCNC IDEA

Ask Dr.

Digital HealthHealthtechWellness & Fitness

Yolandra Hancock(Physician (Dr. Yola))

DeNovX develops technologies to improve crystallization outcomes in pharmaceutical discovery, development, and manufacturing, thereby reducing the cost and time required to bring new drugs to market.

Advanced ManufacturingBiotechDeep Tech

Diagnostic Biochips develops multichannel neural probes for extracellular recording in electrophysiology research, along with cloud-based software for spike sorting and analysis.

BiotechHardwareMedical DevicesGlen Burnie, US

BJBrian Jamieson(Founder & CEO)inFWFan Wu(CTO & VP Product Development)inRobert Seaton Collins(Executive Officer, Director)

Co-investorsTETEDCO

A pharmaceutical company developing treatments for serious chronic diseases with a focus on long-term health solutions and improving medicine access and affordability globally.

BiotechDigital HealthHealthtech

Co-investorsACAccess BiotechnologyBABain Capital Life SciencesRIRidgeback CapitalOXOxford Bioscience PartnersRARA Capital

Digital Artefacts was a digital endpoint technology company offering a modular platform (including BrainBaseline) for capturing cognitive, behavioral, and physiological data in clinical research; it was acquired by Clinical ink, a clinical trial data and technology company focused on eSource and decentralized clinical trials.

AI & Machine LearningDigital HealthHealthtechHorsham, US

Dignify Therapeutics is developing drug programs that induce on-demand defecation and urination to treat functional bowel and bladder disorders, including incontinence and retention associated with neurological conditions and aging.

BiotechDigital HealthMedical DevicesResearch Triangle Park, US

Edward C Burgard(Executive Officer, Director, Promoter)Karl Thor(Chief Scientific Officer)inBWBenny Ward(Executive Officer, Director, Promoter)inAnthony DiTonno(CEO)inEd Burgard(President)Jeff Welch(Chief Operating Officer)

Co-investorsESEshelman Ventures, LLCRARA CapitalMOMontreux Equity Partners

DoseOptics develops Cherenkov imaging technology for real-time radiation visualization in cancer radiotherapy, helping clinical teams verify treatment accuracy and reduce delivery errors.

Deep TechHardwareHealthtechMedical DevicesDartmouth, US

Doty Scientific designs and manufactures scientific instrumentation for nuclear magnetic resonance analysis, primarily CP/MAS probes used to determine the chemical structure of solid materials.

Deep TechEnterprise SoftwareHardwareMedical DevicesColumbia, US

Judy M. Doty(Co-Founder, Operations Manager, Board of Directors)JB Spitzmesser(Co-Founder, Senior Manufacturing Engineer)Dr. F. David Doty(President and Chief Engineering Scientist)

Electronic Bio designs low-noise electronic systems for measuring nanopores and ion channels, with applications in DNA sequencing, ion channel characterization, and chemical sensing.

BiotechDeep TechHardwareSan Diego, US

Co-investorsCHCheckmate Capital Group LLCSASand Hill Angels

Endomimetics develops peptide-based nanotechnology coatings and gels, particularly its proprietary Bionanomatrix, designed to enhance the safety, healing, and longevity of medical implants and devices across cardiovascular, neurovascular, orthopedic, and other medical applications.

BiotechDeep TechMedical DevicesNew MaterialsBirmingham, US

Dr. Brigitta C. Brott(Co-founder)Dr. Ho-Wook Jun(Co-founder & Chief Scientific Officer)Dr. Joseph N. Garner(Chief Executive Officer)

EnduRx Pharmaceuticals develops peptide-directed polymeric nanoparticles for tumor-specific delivery of chemotherapy agents and other active pharmaceutical ingredients, aiming to reduce systemic toxicity.

BiotechMedical DevicesTucson, US

David Loynd(President & CEO)

Ension is a product design and development company focused on the clinical translation of medical technologies, working under FDA design controls and ISO standards.

HealthtechMedical Devices

Envisagenics uses AI-driven analysis of RNA splicing to discover novel drug targets for immuno-oncology and neurodegenerative diseases.

AI & Machine LearningBiotechMedical DevicesNew York, US

MAMartin Akerman, PhD(CEO & Co-founder)MAMartin Akerman(Founder)inMLMaria Luisa Pineda(Founder)in

Co-investorsDODolby Family VenturesDYDynamk CapitalHAHAWKTAILM1M12 (Microsoft's Venture Fund)MAMadrona Venture GroupRERed Cell Incubation+1 more

EpiBone engineers bone tissue from stem cells for regenerative medicine and clinical reconstruction, serving patients requiring bone grafts or craniofacial repair.

BiotechHealthtechMedical DevicesNew York, US

NTNina Tandon(Co-Founder, CEO)inSBSarindr Bhumiratana(Co-Founder)inGVGordana Vunjak-Novakovic(Director)Elma Hawkins(Director)

BoardRLRobert Langer(Director)DZDavid Zhu(Director)in

Co-investorsBEBeresford VenturesCACatalytic Impact FoundationEMEMV CapitalHAHackensack Meridian Health Bear's DenKEKendall Capital PartnersLILifespan Vision Ventures+4 more

Etiometry develops a clinical decision support platform that uses continuous streams of physiologic data to quantify clinical risks for patients in hospital critical care and intensive care units.

AI & Machine LearningDigital HealthHealthtechMedical DevicesBoston, US

EBEvan Butler(Chief Operating Officer and Co-Founder)inDBDimitar Baronov(Chief Technology Officer and Co-Founder)Peter Rock(Chief Financial Officer)Jesse Lock(Chief Medical Officer)SCShane Cooke(President & Chief Executive Officer)inHBHoward Brick(Chief Strategy Officer)in

Co-investorsESEscalate Capital Partners

An all-in-one platform for ABA (Applied Behavior Analysis) providers that combines scheduling, billing, and real-time data collection with compliance and practice management tools.

Digital HealthHealthtechSaaS

Exscien Corporation was an Alabama-based research entity focused on mitochondrial DNA (mtDNA) repair, developing a proprietary fusion protein platform to deliver DNA repair enzymes into mitochondria and protect cells from oxidative damage.

BiotechDeep Tech

eNew Beginnings Program (eNBP) offers research-based online parenting classes to help divorced or separated parents support their children's adjustment.

EdTechWellness & Fitness

FocusStart selects early-stage medical technologies and develops them through testing, validation, and commercialization phases before seeking strategic partnerships for regulatory approval.

Deep TechHardwareHealthtechMedical Devices

For-Robin develops biomedical imaging technology for cancer detection and diagnosis, with planned clinical trials beginning in 2026.

BiotechDigital HealthMedical DevicesBuffalo, US

Dr. Kate Rittenhouse-Olson(President, Founder)Dr. Olson(Chairman/Vice President)Dr. Quataert(Chief Executive Officer)Kate

GameTheory is a consultancy or design firm that develops human-centered, adaptive solutions aimed at creating sustainable social impact, working alongside partners and the people affected by the challenges it addresses.

Impact & Social Good

Co-investorsVEVermont Center for Emerging Technologies (VCET)

GeneTAG develops diagnostic qPCR probes and detection systems for identifying infectious diseases, cancer mutations, and cellular biomarkers.

BiotechDeep TechDigital HealthMedical Devices

Dr. David Shafer

GeoVax Labs is a clinical-stage biotechnology company developing vaccines and immunotherapies for high-consequence infectious diseases and solid tumor cancers.

BiotechHealthtech

GlycoScientific develops reagents for studying protein modifications linked to diseases such as cancer, diabetes, and neurodegenerative disorders.

BiotechDeep Tech

BiotechRichmond, US

Michael D. Grisham(Chief Executive Officer)in

Co-investorsAMAmgen VenturesVEVensana Capital

Great Lakes NeuroTechnologies develops bioinstrumentation products including physiological monitors and patient-centered diagnostic and therapy systems with wireless, remote, and web-based applications.

Digital HealthHealthtechMedical Devices

Gust provides a platform for startup founders to incorporate their companies, manage cap tables and equity, and handle governance, risk, and compliance.

Enterprise SoftwareFintechFuture of WorkLegalTechSaaSNew York, US

DSDavid S. Rose(Executive Officer, Director)in

BoardHMHoward Morgan(Director)in

Co-investors3737 AngelsANAngels4WomenBEBeacon AngelsBRBroad Street AngelsFAFashion Capital PartnersIUIU Ventures+11 more

Hager Bio develops a small-molecule drug discovery platform targeting central nervous system disorders by modulating multiple signaling pathways simultaneously to achieve better therapeutic efficacy with fewer side effects.

BiotechDigital HealthHealthtech

Bel Mekonnen(Founder, President & CEO)John Butera(Chief Scientific Officer & SVP of Research)

Healionics develops STARgraft, a synthetic vascular graft built on its STAR biomaterial scaffold that resists occlusion and infection to create a reliable bloodstream access site for kidney dialysis patients.

BiotechMedical DevicesNew MaterialsSeattle, US

BRBuddy Ratner(Director)MCMike Connolly(Executive Officer, Director)inAndrew Marshall(Director)Max Maginness(Executive Officer)

BoardRyan Takeuchi(Director)Arthur Coury(Director)

Co-investorsALAlliance of AngelsBABand of AngelsCECentral Texas Angel NetworkISiSelect FundKEKeiretsu ForumMEMEDA Angels+1 more

BiotechMarlborough, US

Alon Singer(Executive Officer, Director, Promoter)inLarry Pearson(Director)Sheppard Mollick(Director)

Co-investorsARArieal Southeast Angel Partners

HemoSonics develops FDA-cleared viscoelastic testing (VET) technology that provides real-time hemostasis data at the point of care for hospital teams managing bleeding in obstetric, trauma, and surgical settings.

HardwareHealthtechMedical DevicesCharlottesville, US

FVFrancesco Viola(Manager)inTimothy J. Fischer(Manager)William F. Walker(Manager)

BoardJosep Manent(Manager)William P Moffitt(Manager)Mark Wheeler(Director)

BiotechPlymouth, US

Douglas Wicks(Founder)Patrick M. Schlievert(Founder)William Falkner(Founder and Chairman of the Board)TBThomas Burke(Executive Officer, Director)

BoardJohn Bullion(Director)Williamson Bradford(Director)

Imanis Life Sciences is a contract research organization staffed by virologists, immunologists, molecular biologists, and assay scientists that provides laboratory and development services to help clients accelerate therapy development.

BiotechHealthtechRochester, US

Dr. Stephen Russell(Executive Officer, Director, Promoter)in

ImCare Biotech develops diagnostic biomarkers and therapeutic drugs targeting liver diseases, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

AI & Machine LearningBiotechDigital HealthMedical DevicesDoylestown, US

XLXuanyong Lu(President & Co-Founder)inAYAaron Yefei Lu(Chief Executive Officer)Karteek Kadimisetty(Chief Science Officer)inXuanyong Lu, PhD(Executive Officer, Director)

BoardFelix Y. Lu(Director)

Antigen Discovery provides proteome microarray technology and research services for biomarker discovery, vaccine development, and therapeutic antibody identification.

BiotechDeep TechMedical DevicesIrvine, US

Xiaowu Liang(Co-founder, Chairman & CEO)Angela Yee(Co-founder, Board Member, COO & CFO)

InvivoAX provides an AI-native platform that automates segmentation and extraction of radiomic biomarkers from multimodal biomedical imaging (CT, MRI, PET, and optical scans), converting raw images into structured, analysis-ready datasets.

AI & Machine LearningBiotechHealthtech

InferLink applies artificial intelligence and statistical inference to solve complex problems for clients across multiple sectors.

AI & Machine LearningData & InfrastructureDeep TechEnterprise Software

Steven Minton(President and Founder)

Integral BioSystems is a contract research organization specializing in drug delivery and complex pharmaceutical product development, serving the pharmaceutical and biotech industry from the pre-clinical stage through product formulation.

BiotechDeep TechHealthtechMedical DevicesBedford, US

Shikha P. Barman(Founder, President and CEO)Dave Karasic(Co-Founder, Chief Operations Officer, Legal Counsel and IP)

IsoPlexis offers the Cell Analysis Suite (CAS), software for its Beacon optofluidic platform that lets researchers design, automate, and analyze functional live single-cell workflows.

AI & Machine LearningBiotechDeep TechMedical DevicesSaaSNew Haven, US

Rong Fan(Director)Sean McKay(Executive Officer, Director)Sean Mackay(Executive Officer, Director)inRaj KhakharinJing Zhouin

BoardDaniel Wagner(Director)

Co-investorsCOConnecticut InnovationsALAlly Bridge GroupIRIronwood CapitalNONorthpond VenturesSPSpring Mountain Capital

iVeena Delivery Systems is a clinical-stage ophthalmology company developing pharmacologic eye-drop therapies for refractive eye diseases, including IVMED-80 for keratoconus and IVMED-85 for pediatric myopia.

BiotechHealthtechMedical DevicesSalt Lake City, US

BABalamurali Ambati(Executive Officer, Director)Gerald Simmons(Executive Officer)NWNed Weinshenker(Executive Officer, Director)in

BoardDavid Robinson(Director)James Jensen(Director)Greg Jones(Director)

iXpressGenes operates a CLIA-certified, CAP-accredited molecular diagnostics laboratory that provides genetic testing and analysis services.

BiotechDigital HealthMedical DevicesHuntsville, US

John Schmitt(Executive Officer, Director)inJNJoseph Ng(Executive Officer, Director)

BoardPeggy Sammon(Director)Barbara Fisk(Director)

Co-investorsGEgener8tor

Jan Biotech develops molecular diagnostics that directly detect RNA at the cellular level using its patented RNAamp chemical amplification technology, applied to quantifying latent HIV reservoir cells and discriminating Covid-19 variants.

BiotechHealthtechMedical Devices

KAER develops aerosolization systems (AeroPulsR for aqueous aerosols and SUPRAER for dry aerosols) that generate high-concentration respirable aerosols from liquid APIs, biologics, and advanced formulations for delivery to pediatric and adult patients in critical, acute, chronic, and home respiratory care.

BiotechHealthtechMedical Devices

Key Tech designs and develops medical, industrial, and consumer products using advanced technologies including sensors, wireless systems, ultrasound, microfluidics, optics, and robotics.

Advanced ManufacturingDigital HealthHardwareHealthtechMedical DevicesSaaSBaltimore, US

Jenny(Founder and former CEO)Scott(Co-founder)

KIYATEC develops 3D Predict, a tumor-specific testing platform that uses patient-derived tumor cells to predict how individual cancers respond to therapies.

BiotechDigital HealthHealthtechMedical DevicesGreenville, US

Matthew Gevaert(Director)EPEric Perreault(Executive Officer, Director)inMRMelissa Rayner(Executive Officer)inSIScott Isacksen(Executive Officer)inDEDavid E Orr(Chief Operating Officer)in

BoardCBChristopher Brotherton(Director)

Co-investorsATAtlanta Technology AngelsSESeae VenturesVEVentureSouth

Klein Buendel is a women-owned research and communication firm that develops health communication materials and conducts multimedia production and research.

Digital HealthHealthtechImpact & Social GoodLakewood, US

Mary K. Buller

LayerBio develops ophthalmology therapies, including OcuRing, a bioerodible sustained-release drug delivery technology designed to work with standard intraocular lenses (IOLs) used in cataract surgery.

BiotechHealthtechMedical Devices

Lebrun Labs is a toxicology company that develops and commercializes nonanimal, human-relevant toxicity tests, offering contract testing, test kit manufacturing, and licensing across ocular, dermal, and systemic organ endpoints.

BiotechHealthtechNew MaterialsAnaheim, US

LTI develops prosthetic and orthotic technologies and conducts research to improve outcomes for individuals with limb loss.

Deep TechDefense TechHealthtechMedical DevicesHolliston, US

Localized Therapeutics is a pre-revenue biotechnology company developing therapeutic resonance technology to treat cancer by identifying resonance frequencies specific to a patient's tumor DNA and generating those frequencies to destroy cancer cells while sparing healthy tissue.

BiotechHealthtechMedical Devices

LumiThera develops the Valeda Light Delivery System, an FDA-authorized photobiomodulation (PBM) device that applies multiple light wavelengths to treat early and intermediate dry age-related macular degeneration (AMD).

BiotechHealthtechMedical DevicesPoulsbo, US

TPTracy Puckett(Executive Officer)Clark Tedford(Executive Officer, Director)inSBScott Bradley(Executive Officer)inDMDuane Morrison(Executive Officer)inCCCindy Croissant(Executive Officer)RMRyan Montecucco(Executive Officer)

Co-investors3E3E Bioventures CapitalEFEFung CapitalKEKeiretsu ForumLILife Sciences Greenhouse InvestmentsIMImagine VenturesKEKeiretsu Capital

Luna Innovations develops fiber optics, nanomaterials, and precision assembly solutions across multiple technical domains.

Advanced ManufacturingData & InfrastructureDeep TechHardwareNew MaterialsRoanoke, US

SAScott A. Graeff(Executive Officer, Director)inDavid Chanley(Director)Gary Spiegel(Director)George Gomez-Quintero(Executive Officer)Thomas Oldemeyer(Executive Officer)Brian J. Soller(Executive Officer)

Co-investorsPEPerot Jain

Magnetic Particle Imaging (MPI) is an imaging technology that detects iron oxide nanoparticle tracers using time-varying magnetic fields to create medical images with high contrast and sensitivity.

Deep TechHealthtechMedical Devices

Co-investors5A5AM VenturesAIAimTop VenturesALAlumni VenturesCLCloudStone CapitalEVEvolution VC PartnersGAGaingels+5 more

Mainstream Engineering develops and manufactures thermal management, power systems, refrigerated containers, and specialty products for government, military, commercial, and industrial applications.

Advanced ManufacturingDeep TechDefense TechEnergyHardwareRockledge, US

MAKScientific is a pharmaceutical company developing small-molecule drugs that target the endocannabinoid system, including cannabinoid receptors and regulatory enzymes, to treat conditions such as substance use disorders and metabolic diseases.

BiotechHealthtechBoston, US

MedChem Partners provides contract medicinal chemistry and custom synthesis services for early-stage pharmaceutical companies, functioning as an external chemistry department.

BiotechHealthtechMedical DevicesWatertown, US

Tsvetelina Lazarova(Co-Founder)Steven Riesinger(Co-Founder)

MedShape develops foot and ankle surgical implants and instruments, including total ankle replacement systems, plating, screws, staples, biologics, and NiTiNOL-based dynamic compression devices such as the DynaNail family.

BiotechHealthtechMedical DevicesAtlanta, US

BoardNiles Noblitt(Director)Paul F. Hills(Director)

Co-investorsINIn-Q-Tel

Miyazaki Enterprises produces realistic training models for surgical simulation, particularly in gynecology.

EdTechHealthtechMedical DevicesWinston-Salem, US

Douglas W. Miyazaki(Co-founder, Senior Partner)Dr. Miyazaki(Founder & Board-Certified OB/GYN)

Modulation Therapeutics discovers and develops novel drug candidates targeting aggressive cancers and liver disease using peptide-based, small molecule, and targeted radio-therapy approaches.

BiotechMedical DevicesMorgantown, US

Lori Hazlehurst(Chief Executive Officer & Co-founder)Mark McLaughlin(Executive Vice President & Co-founder)

Co-investorsFLFlorida Technology Seed Capital Fund

Molecular Assemblies uses a Fully Enzymatic Synthesis (FES) technology to produce long, pure, and accurate synthetic DNA oligonucleotides, up to 400 bases, without post-synthesis purification.

BiotechDeep TechNew MaterialsSan Diego, US

J. William Efcavitch, Ph.D.(Treasurer and Chief Scientific Officer)MJMichael J. Kamdar(President, Chief Executive Officer and Secretary)Bill Efcavitch(Founder)Curt Becker(Founder)

BoardDavid Hwang(Director)Larry Stambaugh(Chairman of the Board of Directors)

Co-investors1111.2 CapitalDCDCVC (Data Collective)ISiSelect FundKEKeshif VenturesRIRising TideALAlexandria+3 more

Molecular Express provides formulation services and advanced solutions for scaling novel compounds used in vaccine and therapeutic drug development.

BiotechDeep TechHealthtech

Molecular Targeting Technologies develops and sells specialty chemistry research products, including cell membrane labels, apoptosis labels, fluorescent dyes, click chemistry reagents, crosslinkers, and optical imaging agents.

BiotechDeep Tech

MT develops cancer-specific molecular imaging agents (probes) targeting a common oncoprotein in the tumor microenvironment, intended for use with imaging modalities such as CT, PET, MRI, SPECT and ultrasound.

BiotechHealthtechMedical DevicesOhio, US

Audrey Carballo

Co-investorsCWCWRU Technology Ventures

Multimeric Biotherapeutics develops FortiVac, a vaccine platform technology for infectious diseases and cancer immunotherapies.

BiotechHealthtechMedical DevicesSan Diego, US

Richard S. Kornbluth(President & Chief Scientific Officer)David A. Roth(Chief Operating Officer)Marc Herz(Board Chair)