National Institutes of Health (NIH) — 2022 Investments
195 investments dated 2022 · listed companies and verified rows first · show all
AbbraTech develops a platform technology for discovering and validating antibody therapies targeting disease.
BiotechBranford, US
Advertent Biotherapeutics is a biotechnology company developing first-in-class biologics that modulate TGF-β family growth factors to protect muscle quality and promote regeneration in neuromuscular disorders, with a particular focus on muscular dystrophies.
BiotechDeep TechHealthtech
Monique Floer(Co-Founder, President & CEO)Erik M. Martinez-Hackert(Co-Founder & CSO)
HealthtechSaint Paul, US
Morgan E. Evans(Executive Officer, Director)Morgan Clyburn(Executive Officer, Director)Robert A. Kukuljan(Executive Officer)
BoardKathleen Tune(Director)Micah Eimer(Director)Mark Pacyna(Director)
Altay Therapeutics develops small molecule inhibitors targeting transcription factors to treat serious diseases including facioscapulohumeral muscular dystrophy and cancer.
BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US
Ananya Health develops a portable, battery-powered cryoablation platform for treating pre-cancerous cervical lesions at the point of care in any clinic setting.
FemTechHardwareHealthtechMedical DevicesSan Francisco, US
Anu Parvatiyar(Founder)inWei-Hsiang Chang(Director)
Atelerix Life Sciences develops novel respiratory therapies for drug-induced respiratory depression, respiratory disease exacerbations, and bio-defense against respiratory threats.
BiotechHealthtechMedical DevicesIndianapolis, US
David Kalergis(Executive Officer, Director, Promoter)William Akridge(Director)Peter Barton Hutt(Director)
AtlasXomics develops spatial epigenomics tools, spanning chip fabrication, hardware, and bioinformatics, for researchers studying areas such as cancer and systems biology.
BiotechDeep TechHealthtechNew Haven, US
Gregory Ho(Director)Richard Andersson(Director)Kenneth Wang(Investor and entrepreneur (board member))
BRAINBox Solutions develops a diagnostic and prognostic platform for mild traumatic brain injury that combines blood biomarker panels, neurocognitive testing, and AI-driven scoring to provide objective evidence of injury and predict post-injury symptoms.
AI & Machine LearningBiotechHealthtechMedical DevicesHouston, US
Robert Sledd(Director)Steve Wallace(Executive Officer)Scott Gazelle(Director)
BoardMarc Goldberg(Director)Donna Edmonds(Executive Officer, Director)Vikram Chaudhery(Director)
BrainCheck provides digital cognitive assessment and care planning tools that help healthcare providers screen for and monitor cognitive decline, supporting patients and caregivers.
Digital HealthHealthtechSaaSHouston, US
Yael Katz(Executive Officer, Director)David Eagleman(Executive Officer, Director)
Clarametyx develops novel immune-enabling therapeutics targeting bacterial biofilms to modify disease progression in patients with chronic respiratory diseases.
BiotechHealthtechMedical DevicesColumbus, US
David Richards(Executive Officer)Peter G. Kleinhenz(Director)Michael Layman(Director)William Baumel(Director)Chuck Bramlage(Director)Larry Edwards(Director)
A mobile app aimed at helping reduce opioid use disorder, described in the context of telehealth and prescription management for patients and healthcare providers.
Digital HealthHealthtechMental HealthRaleigh, US
Barry L Jenkins(Executive Officer, Director)
DataJoint provides a computational database that codifies experiments, pipelines, and results as reproducible, governed scientific data for life sciences R&D teams.
AI & Machine LearningBiotechData & Infrastructure
Diadem is a diagnostics company developing AlzoSure, a plasma/blood-based test that uses a proprietary antibody targeting a specific conformation of the p53 protein to predict and diagnose Alzheimer's disease.
BiotechDigital HealthMedical Devices
BiotechHouston, US
Drew Pardoll(Director)Brian Mooney(Executive Officer)Daniel Watkins(Director)Francis Patrick McCormick(Director)Frank Tufaro(Executive Officer, Director)Isaac Cheng(Director)
EpiVario is a biotechnology company developing small-molecule ACSS2 inhibitors that target a neuroepigenetic process involved in long-term memory formation, aimed at treating PTSD and substance use disorders.
BiotechHealthtechMental HealthPhiladelphia, US
Thomas Kim(Executive Officer, Director)Eric Schultenover(Director)Michael Dishowitz(Director)Shelley Berger(Co-Founder)Philipp Mews(Co-Founder)
Estrigenix Therapeutics is a drug development company focused on women's health, using estrogen biology and chemical libraries to develop treatments for menopause symptoms.
BiotechFemTechHealthtechWauwatosa, US
Daniel Sem(Executive Officer, Director)William Donaldson(Executive Officer, Director)Karyn Frick(Executive Officer)Patricia Scheller(Director)Victoria Zellmer(Executive Officer)
EVOQ Therapeutics develops immunotherapies for autoimmune diseases using its proprietary NanoDisc technology, which delivers disease-specific antigens to dendritic cells via subcutaneous administration to restore native immune tolerance.
BiotechHealthtech
FluoroFinder offers an AI-enabled platform for designing flow cytometry and fluorescent microscopy experiments, analyzing marker and fluorophore combinations across more than 3 million products from 78+ suppliers.
AI & Machine LearningBiotechSaaSWestminster, US
Ron Lowy(Manager)James Franklin(Manager)William Marshall(Manager)John Allen(CEO, Manager)Roland Marcus(Founder, Manager)
GeneLancet develops proprietary LgRNA technology for precise gene editing, with applications in CRISPR polymerase-directed therapies targeting neurodegenerative diseases and cancers with unmet medical needs.
BiotechDeep TechHealthtech
Glyphic Biotechnologies develops ProSE™, a high-throughput de novo protein sequencing technology for analyzing proteomes with single-molecule sensitivity.
BiotechDeep TechBerkeley, US
Joshua Yang(Founder & CEO)Daniel Estandian(Founder)Ed Boyden(Founder)Jimmy Yun(Director)
BoardCraig Asher(Director)
Hunterian Medicine is a gene editing company developing CRISPR-based therapies, with a patented platform that enables delivery through a single adeno-associated virus (AAV) to address the CRISPR delivery problem.
BiotechDeep TechBaltimore, US
Vinod Jaskula-Ranga(Executive Officer, Director)
Injectsense develops an ultra-miniature, wireless, rechargeable implantable smart sensor that continuously measures parameters inside the body such as absolute pressure, oxygenation, and motion, providing physicians with 24/7 health data.
Digital HealthHardwareMedical DevicesEmeryville, US
Enrique Malaret(Executive Officer, Director)Ariel Cao(Executive Officer, Director)Zack Scott(Director)
Active seed-stage healthcare company
Eugene, US
Jan Hardorp(Director)Phillip Scripa(Chief Financial Officer and Secretary)William Shortt(Chief Operating Officer)Nicholas Allen(Chief Executive Officer)
FemTechHealthtechWellness & FitnessSanta Monica, US
Stephanie Canale(Executive Officer, Director)Melissa Gee(Director)Eric Canale(Executive Officer, Director)
LEAH Labs engineers gene-edited CAR-T cell therapies to treat cancer in pet dogs, with the goal of generating translational insights for human cancer therapy.
AI & Machine LearningBiotechHealthtechMedical DevicesMinneapolis, US
Wesley Wierson(Founder)inStephen C. Ekker(Scientific Founder & Board Director)Saad S. Kenderian(Scientific Founder)Jonathan P. Mochel(Scientific Founder)Alex M. Abel(Chief Scientific Officer)
Linshom Medical manufactures a wearable, FDA-cleared respiratory monitoring device that provides operating room quality respiratory data at the patient bedside, designed to detect early signs of respiratory problems and reduce adverse events in post-surgical and other patient care settings.
HealthtechMedical Devices
Dave Smith(Founder)
Million Marker provides testing and solutions to help people understand and reduce their exposures to toxic chemicals and environmental contaminants.
FemTechHealthtechWellness & FitnessSan Francisco, US
Jenna Hua(Founder)in
BiotechNational Harbor, US
Dave Krasne(Executive Officer)Eric C. Broyles(Executive Officer, Director)Jacques P. Walker(Executive Officer, Director)
NeurOptics manufactures the NPi-300 pupillometer, a handheld medical device that measures pupil size and reactivity for critical care assessment in hospitals.
HealthtechMedical DevicesIrvine, US
Kamran Siminou(Executive Officer, Director)Joseph Kiani(Director)William Worthen(Executive Officer, Director)
BoardBob Mellen(Director)
NovoPedics is developing MeniscoFix, a resorbable implant placed via arthroscopically-assisted surgery to replace the entire medial or lateral meniscus of the knee, intended to relieve pain, restore mobility, and prevent osteoarthritis in patients with severe meniscal injuries.
BiotechHealthtechMedical DevicesMonmouth Junction, US
Charles J. Gatt, Jr., MD(Founder & CEO)Michael G. Dunn, PhD(Founder & Secretary/Treasurer)Kevin Weadock, PhD(Chief Operating Officer)
Orthobond develops proprietary antimicrobial nanosurface technology that covalently binds to metallic and polymeric surfaces to mechanically kill bacteria, viruses, and fungi without antibiotics or eluting chemicals.
HealthtechMedical DevicesNew MaterialsMonmouth Junction, US
David Nichols(CEO)Peter Goodwin(Director)Frank Cammisa(Director)Khalil Barrage(Director)Lisa D'Urso(Director)David Helfet(Director)
Burke, US
Pezzini Joanna(President)Kevin Hill-Byrne(Vice President)
Pelagos Pharma is a therapeutics developer working on "exercise mimetics," drug candidates designed to activate the metabolic, mitochondrial, and structure-function pathways associated with the benefits of aerobic exercise.
BiotechHealthtechLongevity
BiotechUniversal City, US
Paul Bohm(Executive Officer)Agustin Fernandez III(Executive Officer, Director)Aziz Friedrich(Executive Officer)William P. Halford(Executive Officer, Director)
Remmie Health develops AI-powered ear-nose-throat diagnostic solutions for families and telemedicine providers, using a digital otoscope and app to reduce unnecessary doctor visits and improve diagnostic accuracy in primary care.
AI & Machine LearningDigital HealthHealthtechMedical DevicesSeattle, US
Jane Zhang(Founder & CEO)inElijah Tsai(Co-Founder / Applications Engineer)inLorren(Co-Founder / Global Commercial Lead)in
Safe BVM develops flow-guided manual ventilation products, including the Sotair device for clinical use and the SotairIQ manual ventilation training system, aimed at reducing errors such as hyperventilation and overventilation during emergency ventilatory support.
HardwareHealthtechMedical Devices
SafetySpect builds a handheld, multispectral imaging device (CSI) with on-device machine learning that detects biological residues and contamination on surfaces in real time, replacing ATP swab spot testing.
AI & Machine LearningFoodTechHardwareLos Angeles, US
DAVID ALLEN CARROLL(SECRETARY, DIRECTOR)THOMAS KENNEDY BURKE(CFO, DIRECTOR)KENNETH EDWARD BARTON(CEO, DIRECTOR)
A company developing wearable devices combined with artificial intelligence to detect early signs of sepsis in patients outside hospital settings.
HealthtechSan Francisco, US
Robert Quinn(Founder/CEO)inWei-Jien Tan(Founder/CTO)in
Shift Labs develops DripAssist, an FDA-cleared infusion rate monitor that enables safe delivery of gravity IV medications in home and out-of-hospital settings.
Digital HealthHardwareHealthtechMedical DevicesSeattle, US
Beth Kolko(Founder/CEO)inJoseph Mechlinski(Executive Officer, Director)
SonALAsense develops SONALA-001, a tumor-targeting drug used with an ultrasound device as sonodynamic therapy (SDT), a noninvasive treatment for cancers including brain tumors and blood cancers.
BiotechHealthtechMedical DevicesBerkeley, US
Stuart Marcus(Executive Officer, Director)Mark P. de Souza(Executive Officer, Director)
Los Angeles, US
Jason Lehmbeck(Executive Officer, Director)
Talus develops a proprietary platform that measures and modulates the regulome—the body's gene expression control system—in native cellular contexts.
AI & Machine LearningBiotechDeep TechHealthtechSeattle, US
Alex Federation(Founder)inLindsay Pino(Founder)in
BoardOmri Amirav-Drory(Director)J. Seth Strattan(Director)
VeriSIM uses machine learning and computational simulation to accelerate drug development, replacing traditional trial-and-error experimentation with computational prediction to improve success rates and reduce animal testing.
AI & Machine LearningBiotechDigital HealthMedical Devices
Dr. Jo Varshney
Vivo offers live, small-group fitness classes led by certified trainers over Zoom, combining strength training with cognitive exercises for older adults who work out from home.
Digital HealthHealthtechHR TechLongevityWellness & FitnessAtlanta, US
Eric(Founder, CEO)
BoardKendric Speagle(Director)
We The Village offers a clinically validated online program with group and individual coaching that teaches families the skills to support a loved one through addiction recovery.
Digital HealthMental HealthWellness & Fitness
ZBeats is a cardiac technology company offering FDA-cleared electrocardiographic analysis software that transforms ECG signals into structured clinical intelligence for cardiology workflows.
AI & Machine LearningHealthtechMedical Devices
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.






