National Institutes of Health (NIH) — 2021 Investments

BioRestorative Therapies develops cell- and tissue-based therapeutic products, primarily using adult stem cells, targeting conditions such as degenerative disc disease and metabolic disorders.

BiotechHealthtechLongevityMelville, US

Mark Weinreb(Chief Executive Officer, Chairman of the Board and President)Robert Kristal(Executive Officer)Francisco Silva(Director, Executive Officer)Lance Alstodt(Director, Executive Officer)inEdward L. Field(President, Disc/Spine Division)Mandy Clyde(Vice President of Operations and Secretary)

Cellectar Biosciences is a clinical-stage oncology company developing targeted cancer therapies using its proprietary PLE (phospholipid ether) delivery platform, which delivers therapeutic payloads directly to cancer cells.

BiotechHealthtechMadison, US

JPJamey P. Weichert(Executive Officer, Director)inJohn E. Friend II(Executive Officer)James V. Caruso(President, CEO and Director)JLJarrod Longcor(Executive Officer)inSimon Pedder(Executive Officer, Director)inChad J. Kolean(Executive Officer)in

FibroBiologics develops fibroblast cell-based therapies for chronic and degenerative conditions, targeting areas such as multiple sclerosis and other autoimmune diseases, degenerative disc disease, wound healing, and age-related organ decline (thymus and spleen).

BiotechHealthtechLongevityHouston, US

POPete O'Heeron(Chairman, Founder and Chief Executive Officer)inJDJason D. Davis(Chief Financial Officer)inRARuben A. Garcia(General Counsel)inHamid Khoja(Chief Scientific Officer)in

BoardStacy Coen(Director)Matthew Link(Director)

Oragenics develops treatments for concussion and traumatic brain injury, focusing on clinical development of therapeutic candidates.

BiotechDeep TechDigital HealthLongevityMedical DevicesTampa, US

AJAlan Joslyn(Executive Officer, Director)inMichael Sullivan(Executive Officer)JHJanet Huffman(Chief Executive Officer & Chief Financial Officer)James P. Kelly(Chief Medical Officer)William Peacock(Chief Clinical Officer)

BoardRobert Koski(Director)

1910 develops an AI platform that integrates multimodal data, frontier AI models, and high-throughput lab automation to accelerate drug discovery and development for pharmaceutical companies.

AI & Machine LearningBiotechDeep TechHealthtechBoston, US

JAJen Asher(CEO)inJOJennifer O. Nwankwo(Executive Officer, Director)JAJen Asher, Ph.D.(Founder)inJen Nwankwo(Founder)

BoardSamir Kumar(Director)Marc Foster(Director)

Co-investorsFOFoundersX VenturesPLPlayground GlobalY Y CombinatorEMEmles Venture PartnersJUJude GomilaM1M12 (Microsoft's Venture Fund)+6 more

2Morrow provides evidence-based digital wellness programs delivered through a smartphone and web app, using Acceptance and Commitment Therapy principles to help people quit tobacco, manage stress, and change health behaviors.

Digital HealthMental HealthWellness & FitnessKirkland, US

JMJo Masterson(Executive Officer, Director)inBrandon Masterson(Executive Officer)in

BoardJohn Koster(Director)ELEric Larsen(Director)in

Co-investorsPOPortland Seed FundALAlliance of AngelsWRWRF Capital

3D Molecular Designs operates SMART Teams, an educational program where students model protein structures using molecular visualization tools and 3D printing to communicate research findings.

BiotechDeep TechEdTechHealthtechMilwaukee, US

Tim Herman(Founder & PhD)Diane Herman(Co-founder & Business Manager)

BoneScore makes the OsteoProbe, a handheld, radiation-free medical device that measures bone tissue strength by delivering a controlled impact and producing a Bone Material Strength Index (BMSi).

Deep TechDigital HealthHealthtechMedical DevicesSanta Barbara, US

Paul Hansma(Co-founder)Alexander Proctor(Co-founder)Steven Dorfman(Director)Peter Burks(Executive Officer)Linda Heller(Director)Bill Casner(Director)

Co-investorsTETech Coast Angels

Acurex is developing CU-00048, a T-type selective calcium inhibitor in clinical development for Essential Tremor, a neurological disorder affecting millions of patients.

BiotechLongevityMedical Devices

Lev Leytes(CEO and Co-Founder, Chairman of the Board)William D. Shrader(CSO and Co-Founder)Galina Leytes(COO and Co-Founder, Director)

BiotechChicago, US

Erik B. Kulstad(President)

BoardMark Ritz(Director)Cliff Turner(Director)Don Morath(Director)Igal Ladabaum(Director)Rick McCaulley(Director)

Advanced Silicon Group works in nanotechnology, using the tagline "Nanotechnology for Life."

BiotechDeep TechMedical DevicesNew MaterialsSemiconductorsLowell, US

MBMarcie Black(CEO & Co-founder)inBill Rever(Chief Marketing and Sales Officer & Co-founder)in

BoardAlan Watson(Director)Sarah Kelly(Director)

Co-investorsTETenon Ventures

Affect Therapeutics operates an app-based digital treatment provider offering care for substance use disorders (alcohol, cannabis, opioid) and mental health conditions like depression and anxiety, using methods such as contingency management, CBT, medication-assisted treatment, and peer support.

Digital HealthHealthtechMental HealthNew York, US

JDJeff DeFlavio(Co-founder)inKMKristin Muhlner(Executive Officer, Director)in

BoardKRKevin Ryan(Director)inJRJeff Rinehart(Director)in

Co-investorsARArtis VenturesCICity LightALAlleyCorpGAGaingelsKAKapor CapitalLILifeArc Ventures+4 more

Affinity Molecules provides protein and antibody production, purification, and characterization services across bacterial, insect, and mammalian expression systems.

BiotechDeep TechHealthtech

AgileMD operates a forum for users and customers to exchange ideas, questions, and techniques related to the company's services and operations.

AI & Machine LearningDigital HealthHealthtechSaaSSan Francisco, US

BSBorna Safabakhsh(CEO)inScott Freedman(Vice President of Sales and Business Developement)Jonathan LeeKurt EricsonZack ListonRobin Horca(Executive Assistant)

Co-investorsMDMDT VenturesY Y Combinator

Aidar (Aidar Health) develops digital medicine solutions that combine physical and digital biomarkers with predictive algorithms to support precision medicine and remote patient monitoring.

AI & Machine LearningDigital HealthMedical Devices

SESathya Elumalai(Founder)in

Co-investorsMAMaryland TEDCOTETEDCO

Pittsburgh, US

Illah Nourbakhsh(Executive Officer, Director, Promoter)

Thumby Color is a pocket-sized gaming device powered by the Raspberry Pi RP2350 processor, featuring a color display and programmable rumble motor.

ConsumerEdTechGamingHardwareAkron, US

Alessa Therapeutics develops a proprietary drug-delivery platform for sustained and localized release of therapies to treat early-stage prostate cancer.

BiotechHealthtechMedical DevicesSan Carlos, US

PMPamela Munster(Founder, Director & Chief Scientific Advisor)inCam Gallagher(President & Chief Executive Officer)inJMJohn Maroney(Executive Officer, Director)in

BoardZCZachary Collins(Executive Officer)inSTSteve Tregay(Director)inAMAnnie Mitsak(Director)in

Co-investorsCUCure VenturesMIMission Bay CapitalMIMission Biocapital

Alida Biosciences develops tools for RNA modification detection and analysis that enable research and diagnostic applications across drug discovery, clinical testing, and biotechnology.

AI & Machine LearningBiotechData & InfrastructureDeep TechHealthtechSan Diego, US

BPByron Purse(Co-Founder)inJDJohn Drewry(Director)inGudrun Stengel(CEO & Co-Founder)

Co-investorsFUFusionX VenturesGEGENERAL INCEPTIONVEVertical Venture PartnersPAPaladin Capital Group

BiotechLaguna Hills, US

George Guikai Wu(Executive Officer, Director)Yonglei Shang(Executive Officer, Director)Weian Zhao(Director)

Amira Learning provides AI-powered reading instruction software for schools, combining the Science of Reading with machine learning to deliver reading growth at scale.

AI & Machine LearningEdTechLas Vegas, US

Peter Jungwirth(Executive Officer)APAdam Porsch(Executive Officer)inASHISH GUPTA(Executive Officer)inMONIKA FLOOD(Executive Officer)inKATIE JANSEN(Director)inRICHARD H. COLLINS(Director)in

Co-investorsAUAUTHENTIC VENTURESGSGSV VenturesOWOwl VenturesVEVertical Venture PartnersRERethink Capital Partners

Amissa Health quantifies symptoms through wearable data and biometric collection to improve clinical care and research, with a focus on early detection of Alzheimer's and digital biomarkers for perimenopause in women.

AI & Machine LearningDigital HealthFemTechHealthtechMedical DevicesCharlotte, US

SSSam Smith(Founder & CEO)inJCJon Corkey(Founder & CSO)in

BoardDJDr. Jaclyn Piasta(Founder, Monarch Health)

Co-investorsPRPrimordial VenturesTETechstars

APCBio Innovations is a consulting and contract research company focused on biopharmaceutical product development, providing protein therapeutics, vaccines, and specialized research reagents using its proprietary production platforms.

BiotechFrederick, US

Apex Bait Technologies develops scientifically-formulated bait products to control urban and agricultural pest insects.

AgTechBiotechSilicon Valley, US

Dangsheng Liang(President and Founder)

Aptus Bioreactors develops bioreactor systems and processes for tissue engineering research, specifically enabling scientists to test and grow heart valve replacements using stem cells and scaffolds.

BiotechDeep TechHealthtechMedical Devices

Dr. Lee Sierad

BiotechAlbuquerque, US

Stephen Brueck(Executive Officer, Promoter)Emily Milsovic(Executive Officer, Director)Steven R.J. Brueck(Director)Scott L. Goldman(Executive Officer, Director, Promoter)Zachary Lerner(Executive Officer)

BoardDBDavid Blivin(Director)in

Co-investorsCOCottonwood Technology FundSUSun Mountain Capital8V8VCALAlumni VenturesDUDurable Capital PartnersLOLockheed Martin Ventures+3 more

Artiam Bio develops CB1 receptor antagonist compounds for treating diseases linked to dysregulated endocannabinoid signaling, including NASH, cannabis use disorder, and Prader-Willi syndrome.

BiotechHealthtechMedical Devices

Ronnie Maitra(Founder & President)Herb Seltzman(Vice President)

ASAKE Biotechnology develops novel therapeutics using biosynthetic technology and synthetic chemistry, with research focused on infectious diseases, diabetes, and cancer.

BiotechDeep TechHealthtechAthens, US

Dr. Shiyong Wu(Founder)

Attune develops a wearable platform that delivers targeted, adaptive focused-ultrasound neuromodulation to the deep brain to affect mood, focus, and performance.

Deep TechMedical DevicesWellness & Fitness

Rajiv Mahadevan(Founder)inKeith Murphy(Co-Founder & CTO)in

Co-investorsGEGenoa VenturesJOJoyance PartnersSTStartX

Auration Biotech develops therapeutics for diseases of the ear, nose, and throat, with programs focused on non-surgical repair of tympanic membranes and an alternative to tympanotomy tubes.

BiotechMedical DevicesChapel Hill, US

Benjamin F. McGraw, III(Executive Chairman)Sanjay Chanda(Development Consultant)Peter Santa Maria(Chairman, SAB)

Avantyx Pharma is developing a small-molecule therapeutic aimed at preventing and restoring nerve damage caused by diabetes and chemotherapy, targeting what it identifies as the root-cause mechanism of peripheral neuropathy.

BiotechHealthtech

Sandra Rieger(Founder & CEO)Bianca Ruiz(Founder & COO)Yangbo Feng(VP Chemistry)

BehaVR develops VR-based (XR) therapeutics for mental and behavioral health, translating clinical science into immersive programs that address stress, anxiety, fear, pain management, addiction recovery, and maternal health.

Digital HealthHealthtechMental HealthElizabethtown, US

Aaron Gani(Executive Officer, Director)

Co-investorsCHChrysalis VenturesKEKeyhorse CapitalPOPoplar VenturesACAccenture VenturesFRFrist Cressey VenturesFUFuture Labs Capital+2 more

BioAesthetics develops NACgraft, a cell-free, collagen-rich nipple-areolar complex graft that a surgeon applies so the patient's own cells integrate it into living nipple and areola tissue.

BiotechHealthtechMedical DevicesNew Materials

JBJuliana Blum(CEO & Director)BHBilly Heim(COO)in

Co-investorsFEFemHealth VenturesHEHemi Ventures, LlcJOJoyance PartnersNENew Orleans Startup FundSOSOSVTHThe Launch Place+2 more

BioLum Sciences develops small molecule probes and bioanalyte detection assays using chemiluminescent, colorimetric, and fluorescent technologies for precision medicine and biomarker detection in research and clinical applications.

BiotechHealthtechMedical DevicesDallas, US

Jack Reynolds(CEO)Dr. Alex Lippert(CSO)Dr. Husain Kagalwala(CTO)

BioPROVAR develops BioTremvar, a biological therapy that targets the primary immune response pathway to reduce excessive inflammation in immune-mediated diseases.

BiotechMedical DevicesHouston, US

Eugene Roussel(Founder, CEO, and Chief Scientific Officer)Marie-Claude Gingras(Founder, Chief Operating Officer)

Bleep designs and sells CPAP masks—specifically the Eclipse™ and DreamPorts®—that prioritize comfort and eliminate common pain points associated with traditional CPAP therapy, serving patients with sleep apnea.

HealthtechMedical DevicesWellness & Fitness

Boston Immune Tech develops immunotherapies for treatment of infectious diseases and cancer.

BiotechHealthtechMedical DevicesBoston, US

Russell LaMontagne(Chief Executive Officer)inDavid Brooks(Chief Medical Officer)in

Co-investorsHAHatteras Venture Partners

Boundless Science is a medtech company with a team of experienced entrepreneurs, engineers, and clinicians working on medical technology projects.

HealthtechMedical Devices

Calyx provides precision sensing and AI-powered flock monitoring solutions for poultry producers, turning camera and sensor data into actionable insights for harvest planning and operational efficiency.

AgTechAI & Machine LearningHardwareIoTBerkeley, US

Co-investorsSOSOSVWIWI Harper Group

Castner Inc. is a healthcare research and consulting firm that combines nursing expertise, public health knowledge, and data analysis to develop evidence-based solutions for improving health outcomes and community well-being.

Climate TechData & InfrastructureDigital HealthEdTechHealthtechGrand Island, US

Syntax Bio operates a stem cell discovery platform, using its Cellgorithm technology to control and accelerate cell differentiation by mimicking human development to generate diverse functional cell types.

BiotechDeep TechMedical Devices

Cellular Logistics develops biological products focused on cardiac treatments, combining expertise in cell therapy and cGMP manufacturing to advance novel therapies for heart failure and interventional cardiology applications.

BiotechHealthtechMedical DevicesNew MaterialsMadison, US

AVAlex Vodenlich(Executive Officer, Director)inEric Schmuck(Executive Officer)Amish Raval(Executive Officer, Director)

BoardPaul Resnick(Director)

Cooler Heads develops scalp cooling technology to prevent hair loss in cancer patients undergoing chemotherapy.

HealthtechMedical DevicesSan Diego, US

KDKate Dilligan(Founder & CEO)in

BoardMGMaria Gonzalez-Blanch(Director)inMSMICHAEL SCHOTZINGER(Director)inLIZ TODIA(Director)LZLIZ ZAMBORY(Director)inJPJASON PESTERFIELD(Director)in

Co-investorsADAd Astra VenturesALAloft VCASAstiaBABacchus Venture CapitalCACAL InnovationCACalifornia Innovation Fund+8 more

BiotechElk Grove Village, US

Ze-Qi Xu(Executive Officer)Wenbin Lin(Director)Jianhua Yang(Director)Xiaochang Dai(Director)

Farmington, US

F. Kevin Didden(Director)Michael Grillo(Executive Officer, Director)Michael Sapack(Executive Officer)ADAlan D Kersey(Executive Officer, Director)inPatrick M. Curry(Executive Officer)

Adam Hanina(Founder)in

Co-investorsBOBoro CapitalCOComcast Ventures

Daxor manufactures and distributes FDA-cleared blood volume analysis (BVA) diagnostic devices for measuring blood volume in clinical settings.

Digital HealthHealthtechMedical DevicesOak Ridge, US

Michael Feldschuh(President & Chief Executive Officer)Jonathan Feldschuh(Chief Scientific Officer)

Defined Bioscience develops cell culture media, growth factors, and related reagents for stem cell biology and regenerative medicine research.

BiotechDeep TechHealthtechMedical DevicesNew Materials

Steve Rees(Co-Founder, CEO)Jerome Karpiak(Co-Founder, VP of R&D)Jose M. Morachis(Founder and Board Chairman)Will Alaynick(Founder and Board Member)

Co-investorsPHPhase Two Ventures

Diatech Diabetes is a medical device company developing SmartFusion, a software platform and mobile app that monitors insulin infusion pumps for medication delivery failure and measures the accuracy of insulin delivery for people living with diabetes.

Digital HealthHealthtechMedical Devices

JWJohn Wilcox(Co-founder & CEO)inLELuis E. Blanco(Co-founder & CTO)in

Co-investorsLALaunch TennesseeSTStarve UpsTATA Associates

Dorian Therapeutics was a biotechnology startup developing senoblockers, drugs designed to rejuvenate cells and tissues by targeting aging-related mechanisms.

BiotechDeep TechHealthtechLongevitySan Francisco, US

MAMaddalena Adorno(Founder)inBDBenedetta di Robilant(Founder)in

Co-investorsBLBlumberg CapitalSTStartXY Y Combinator

Eclipse Regenesis develops a regenerative therapy platform for treating intestinal failure, starting with Short Bowel Syndrome, and extending to other complex gastrointestinal conditions.

BiotechHealthtechMedical Devices

ABAndre Bessette(CEO, Co-Founder)inJDJames Dunn(Co-Founder)TKTom Krummel(Co-Founder)

Co-investorsATAtacama Ventures

Evren Technologies develops bioelectronic therapeutic devices using transcutaneous vagus nerve stimulation (taVNS) to treat PTSD and other neurological and psychiatric conditions.

BiotechDeep TechDigital HealthHealthtechMedical DevicesMental Health

Weaver Gaines(Chairman)

FD Neurotech manufactures specialized staining kits and accessories for neuroscience research and histology applications.

BiotechDeep TechHardwareHealthtechMedical Devices

Fu Du(President)

Co-investorsKEKeiretsu Forum

Fizz Studio develops data visualization and accessibility software solutions, with a focus on making complex data representations accessible to users with visual impairments.

AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSaaS

Doug Schepers(Founder, CEO)

FluidForm Bio uses 3D bioprinting technology to manufacture living human tissue for disease treatment and drug development.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Mike Graffeo(Chief Executive Officer & Co-founder)Adam Feinberg(Chief Technology Officer & Co-founder)

GogyUp develops assistive technology to help adults understand information and develop literacy skills for career advancement.

AI & Machine LearningEdTechSaaS

Gordian Biotechnology develops therapies aimed at treating age-related diseases to extend healthy lifespan.

AI & Machine LearningBiotechHealthtechLongevity

Co-investorsAGage1FIFifty YearsMEMetaplanetPRPrime Movers LabSTStartXSTStreamlined Ventures+3 more

Gradient Medical develops INSPIRE therapy, an interventional oncology treatment that uses engineered electrical pulses to target cancer cells with real-time sensing for clinical control and adaptive energy delivery.

BiotechDeep TechHealthtechMedical Devices

Greffex develops engineered adenoviral vectors for gene delivery, used to manufacture vaccines, gene therapy products, and immune suppression therapeutics.

AI & Machine LearningBiotechDeep TechDefense TechHealthtechMedical Devices

John R. Price(Co-Chairman, President, Chief Executive Officer and Co-founder)Uwe D. Staerz(Chief Scientist and Co-founder)

Gryphon Bio is a clinical-stage company that develops and manufactures blood tests based on brain-specific molecular biomarkers to monitor brain health and detect conditions such as traumatic brain injury, Alzheimer's disease, and mild cognitive impairment.

BiotechDigital HealthHealthtech

Handl Health is an AI platform that aggregates and analyzes publicly available healthcare price transparency data to help insurance brokers and benefits consultants build and maintain affordable health plans for their clients.

AI & Machine LearningData & InfrastructureDigital HealthHealthtechInsurTechCerritos, US

Aishwaria Shah(Executive Officer, Director, Promoter)AMAhmed Marmoush(Executive Officer, Director, Promoter)inRia(Co-founder)inRia Shah(Founder)inScott(Technology/Engineering Leader)inAlison(Marketing Leader)in

Co-investorsARArthur VenturesBOBoutique Venture PartnersEVEverywhere VenturesPLPlug and Play VenturesRIRiverfront Ventures, LLCTATau Ventures+3 more

HDT Bio is a clinical-stage biopharmaceutical company developing novel immunotherapy technologies and products to treat oncology and infectious diseases.

BiotechHealthtechMedical DevicesSeattle, US

Bryan BerubeDavid LaPointeKelli CarabelloShamini Thiagarajan

ImgGyd develops hardware and software for image-guided neurosurgery, including trajectory guides for mm-level precision and custom sterile drapery.

HardwareHealthtechMedical DevicesMadison, US

Immertec develops virtual reality training solutions for medical education, enabling healthcare professionals to practice procedures through immersive technology.

AI & Machine LearningDigital HealthEdTechHealthtechMedical Devices

Erik Maltais(CEO / Co-Founder)Jon Clagg(CTO / Co-Founder)

Co-investorsRERevolution

Immunartes develops preventive therapies against Staphylococcus aureus by neutralizing the pathogen's immune-evasion mechanism, using two modalities: a vaccine for durable immunity and a monoclonal antibody for immediate protection in perioperative and other high-risk hospital settings.

BiotechHealthtechChicago, US

Dominique Missiakas(Founder and Chief Scientific Officer)Vilasack Thammavongsa(CEO and Director of Research)

Immunophotonics is a clinical-stage biotech company developing novel treatments for solid-tumor cancers and infectious diseases by combining tumor ablation with systemic cancer immunotherapy.

BiotechDeep TechDigital HealthMedical DevicesSt. Louis, US

Dr. Hode(Co-Founder & Senior Fellow)Mr. Alleruzzo(Co-Founder & Director)Dr. Chen(Co-Founder)Dr. Robert Nordquist(Co-Founder)Luciano Alleruzzo(Director, Promoter)WCWei Chen(Director, Promoter)

Co-investorsARArgonautic VenturesBIBioGenerator VenturesCECentennial InvestorsISiSelect FundMIMissouri Technology CorporationCUCultivation Capital

Inflammatix develops host-response-based molecular diagnostics tests to identify acute infections and sepsis in emergency and critical care settings.

AI & Machine LearningBiotechHealthtechMedical DevicesBurlingame, US

TSTim Sweeney(Co-Founder and CEO)inPKPurvesh Khatri(Founder)inJRJONATHAN ROMANOWSKY(Co-Founder)inTimothy Sweeney(Founder)

BoardKENNETH BAHK(Director)MICHAEL RUBIN(Director)

Co-investorsKHKhosla VenturesNONorthpond VenturesINInitiate Venture PartnersMAMarram VenturesOSOSF VenturesSTStartX+1 more

Inso Bio develops low-cost workflow automation tools for genomics laboratories to accelerate sample-to-result processing and increase accessibility to genomic analysis.

AI & Machine LearningBiotechDeep TechHardwareMedical DevicesIthaca, US

Harvey Tian(Co-Founder and CEO)inAdam Bisogni(Co-Founder and CSO)in

Co-investors202048 VenturesSOSocial StartsSOSOSVSPSpacecadet Ventures

A professional services site for Alexandra, a business and career expert offering keynote speaking, consulting, and media engagements focused on the global workforce and workplace training.

Future of WorkHR Tech

LifeLoop is a software platform for senior living communities that integrates with electronic health records to streamline administrative workflows and enable resident engagement and enrichment activities.

Digital HealthHealthtechSaaSWellness & Fitness

Javelin Bio offers a microphysiological system platform that simulates human liver biology using primary human cells to provide drug and disease response data for preclinical research.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Murat Cirit(CEO, Cofounder)Emily Geishecker(VP of Operations, Cofounder)

Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.

AI & Machine LearningBiotechLongevityMedical DevicesRedwood City, US

JOJeremy O'Connell, PhD(Chief Scientific Officer and Co-Founder)HYHanadie Yousef, PhD(Co-Founder, Director and Executive Advisor)JOJeremy O'Connell(Director)inDHDr. Hanadie Yousef(Founder)inJulie Anne Smith(Chief Executive Officer and Director)in

BoardBHBen Hemani(Director)in

Co-investorsALAlumni VenturesBABascom VenturesBIBison VenturesCOCompoundHAHarmonix FundHOHorizons Ventures+6 more

K Medical is a healthcare startup developing simple, effective medical solutions, with a current focus on preventing bedsores (pressure ulcers).

HardwareHealthtechMedical DevicesCleveland, US

David Kay(Director)William Fuller(Executive Officer)

ILMUTOTO is a licensed online gaming platform serving Indonesian players with various popular game types, daily bonuses, and 24/7 customer support.

Digital HealthGamingHealthtechWellness & Fitness

KatheraBio develops antifungal therapies targeting cellular enzymes involved in fungal growth and pathogenicity, with applications as monotherapies or combination treatments for drug-resistant fungal infections.

BiotechDeep TechHealthtechMedical DevicesUnion, US

Stephen Parent

Kytopen develops non-viral gene delivery technology called Flowfect that combines fluid flow with electric fields to deliver payloads such as mRNA, DNA, and CRISPR Cas9 RNP into cells for high-throughput transfection.

BiotechDeep TechHardwareCambridge, US

CBCullen Buie(Founder; Board Observer)inPGPaulo Garcia(Founder)inMCMichael Chiu(Chief Executive Officer)in

BoardPMPaxton Major(Director)inADAnn DeWitt(Director)inPaul Wotton(Director)

Co-investorsBABantam GroupHOHorizons VenturesMAMassVenturesSESelvedge VentureTBTBD AngelsTETelegraph Hill Partners+3 more

Lab11 Therapeutics develops host-directed therapeutics using small molecules and mRNA approaches to modulate human immune response against viral infections, targeting prevention and treatment of diseases including influenza and COVID-19.

BiotechDigital HealthHealthtechMedical DevicesNew York, US

Lifetime Omics is a biotech and health-informatics company that builds infrastructure for training clinical AI systems on quality-controlled, integrated data from electronic health records, multi-omics, and imaging while protecting patient privacy.

AI & Machine LearningBiotechDigital Health

Likarda develops a hydrogel encapsulation platform that delivers cell therapies, biologics, and small molecules with customizable release profiles and protection from immune attack.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesLawrence, US

Lisa Stehno-Bittel(Founder, PhD)

LinAmp Technologies designs and manufactures standardized power amplifier modules for cellular base stations operating in 2G, 3G, and 4G networks, serving commercial, medical, and military markets globally.

Deep TechDefense TechHardwareLaguna Hills, US

LinkedIn is the professional network — profiles, connections, job listings and a feed built around work rather than friendship.

Sunnyvale, US

RHReid Hoffman(Founder)inABAllen Blue(Founder)inKGKonstantin Guericke(Founder)inELEric Ly(Founder)inJVJean-Luc Vaillant(Founder)inLHLee Hower(Co-founder)in

Co-investorsDGDG Ventures, Inc.GRGreylock PartnersSASapphire VenturesACAccelBEBessemer Venture PartnersCRCrosslink Capital+6 more

Liv Labs develops pelvic floor fitness products, including the Pippa® Resistance Spring, designed to improve pelvic floor strength for women.

FemTechHardwareHealthtechWellness & FitnessChicago, US

MRMelody Roberts(Founder)inCPCarly Price(Founder)inDMDr. Melissa Stendahl(PT, Co-leader)inTim McKeown(Vice President, Product \u0026 Commercialization)

Co-investorsJOJosephine CollectiveY Y CombinatorHAHarvard Management Company

LongWave Photonics designs and manufactures distributed feedback quantum cascade lasers operating in the terahertz frequency range.

Deep TechHardwareNew MaterialsSemiconductors

Maxwell Biosciences develops therapeutics aimed at treating infectious diseases.

AI & Machine LearningBiotechHealthtechLongevityAustin, US

Joshua McClure(Executive Officer, Director, Promoter)inKate McKinley(Director)inPraveen Tyle(Director)Barbara R Holcomb(Director)Annelise Barron(Director)

Co-investorsCACapital FactoryDADas & Co.KEKeiretsu ForumLOLoftyInc CapitalTRTransform Investments

HealthtechWellness & FitnessWashington, US

Jennifer Newton-Small(Executive Officer, Director)

Co-investorsARArgon VenturesONOne Planet GroupPIPixel Perfect VenturesTETechstars

Mercator MedSystems develops catheter-based Micro-Infusion technologies, including the Bullfrog Micro-Infusion Device, for the local delivery of pharmacologic and biologic agents to the peripheral vasculature.

BiotechHealthtechMedical DevicesSan Leandro, US

KPKirk P. Seward(Co-founder, President and CEO)inTrent Reutiman(Executive Officer, Director)Stephen Baker(Executive Officer)Charles Crocker(Director)Doug Wall(Director)

BoardNSNed Scheetz(Director)in

Co-investorsAPAphelion CapitalMEMedvest Capital

METIS-DoSense Health Analytics offers a platform that measures quality in medical imaging practice, assessing medical image quality and radiation dose at the organ level in individual patient images.

Digital HealthHealthtechMedical Devices

Minutia develops insulin-producing cell transplants that can be monitored in vivo over time, aimed at improving cell replacement therapy for diabetes.

BiotechDeep TechDigital Health

Co-investorsBIBioBritDEDemos Strategic Investing PartnersSOSOSVLULucas Venture Group

MiResource helps people find and connect with affordable mental health care tailored to their needs, ranging from counseling to psychiatric treatment and crisis services.

B2B MarketplacesHealthtechMental HealthSaaS

MDMackenzie Drazan(CEO of MiResource)inGAGabriela Asturias(COO of MiResource)in

Co-investorsDRDraper AssociatesRORoyal Street Ventures Management Company, LlcSTStartX

Molecular Instruments develops HCR (hybridization chain reaction) imaging products for enzyme-free, multiplex, quantitative in situ hybridization and immunofluorescence, enabling detection of RNA and protein targets.

BiotechDeep TechHardwareHealthtechMedical DevicesLos Angeles, US

DHDr. Harry M.T. Choi(Founder & CEO)PNProf. Niles A. Pierce(Founder & Chair of the Board)

Co-investorsFRFREEFLOW

MyExposome develops passive sampling wristbands and data analytics software to measure individual chemical exposures and support epidemiological research.

BiotechData & InfrastructureHardwareHealthtech

Marc I. Epstein(Chief Executive Officer and Co-Founder)Kevin A. Hobbie(Co-founder)Steven G. O'Connell(Senior Scientist and Inventor of Core Technology)Kim A. Anderson

BiotechJupiter, US

CMCourtney Miller(Executive Officer, Director)inPatrick Griffin, Ph.D.(Director)Dave Adams(Director)Andrew Ritter(Director)Robert Finizio(Director)Theodore Kamenecka(Director)

Co-investorsFLFlorida Opportunity FundDEDeepWork CapitalMAMayo Clinic Ventures

Nalu Scientific designs mixed-signal integrated circuits and data acquisition systems for precision measurement, including particle tracking and time-of-flight applications.

Deep TechHardwareSemiconductorsHonolulu, US

NanoDiagnostic Technology LLC (NDT) develops platforms that combine smartphones, nanosensors, and cloud software for point-of-care diagnosis and point-of-need detection.

BiotechCloud ComputingMedical Devices

Nano Imaging Services is a US-based contract research organization (CRO) with in-house cryo-EM microscopes, providing protein production and cryo-electron microscopy services.

BiotechDeep TechHealthtechSan Diego, US

BCBridget Carragher(Director)inClinton S. Potter(Director)JRJohn Rigg(Executive Officer, Director)inJLJanine LeBlanc(Executive Officer)inPHPeter H. Glick(Executive Officer, Director)inBrian Conkle(Executive Officer)

Co-investorsAMAmpersand

NanoPin Technologies develops diagnostic platforms for infectious diseases including tuberculosis, HIV, and COVID-19 using nanotechnology-based approaches to detect biomarkers in patient samples.

BiotechDigital HealthHealthtechMedical Devices

Tony Hu(Co-founder, Science Advisor)Thomas Tombler(Co-founder)

GECHO is an FDA-cleared clinical software workstation for contrast-enhanced echocardiography that helps cardiologists assess left ventricular function and myocardial blood flow through enhanced imaging and patented Time-to-Replenish spatial maps.

AI & Machine LearningHealthtechMedical Devices

Nema Life provides bioactive screening and mechanism discovery services using microfluidic automation of Caenorhabditis elegans worms paired with computer vision and AI to measure efficacy across health domains.

AI & Machine LearningBiotechDeep TechFoodTech

BiotechPortland, US

VLADIMIR BOGIN(Executive Officer, Director)

Nova Thin Film develops oral soluble film (OSF) drug delivery technology called DepoFilm, working with pharmaceutical partners on proprietary products as well as its own drug candidates.

BiotechHealthtechMedical Devices

Joseph Fuisz(Management/Board (JD))Madhu Hariharan(Management/Board)Kurt Lauenstein(Management/Board)

ObjectiveEd develops digital curriculum and performance monitoring tools designed for students with disabilities, as well as the parents and professionals supporting their education.

AI & Machine LearningEdTechImpact & Social Good

Co-investorsGOGood Growth Capital

BiotechBaltimore, US

Praveen Sinha(Executive Officer, Director)Daniel Roche(Director)Todd McNutt(Executive Officer, Director)

Clinical-stage oncology company developing cancer treatments

BiotechDel Mar, US

Dana McGowan(Treasurer and Secretary)Karen Lundgren(Vice President and Chief Scientific Officer)LGLauren G. Otsuki(Chief Business Officer)inJames Freddo(Chief Medical Officer)James B. Breitmeyer, M.D., Ph.D.(President and Chief Executive Officer)

BoardDavid F. Hale(Director)

Co-investorsMEMESA VERDE VENTURE PARTNERSVEVedanta Capital

Optimeos develops a nanoparticle-based drug formulation and delivery platform (CINCs and LINCs) for complex biologics including mRNA, DNA, peptides, and proteins, targeting rare diseases, immunology, and metabolic conditions such as obesity.

BiotechDeep TechHealthtechPrinceton, US

Robert K. Prud'homme, PhD(Director)BPBob Prud'homme(Leadership (PhD))RPRob Pagels(Leadership (PhD))CMChet Markwalter(Leadership (PhD))inSHShahram Hejazi(Leadership (PhD))inGHGregory Harriman(Leadership (MD))in

Co-investors7G7G BioVenturesANAnzu PartnersHAHatch BioFund

Outcome Referrals provides a behavioral health assessment and matching system called the Treatment Outcome Package (TOP) to connect patients with personalized mental health care and help payers implement value-based reimbursement models.

AI & Machine LearningDigital HealthHealthtechMental HealthFramingham, US

DRDavid R. Kraus, PhD(Founder & President)DRDavid R. Kraus(President and CEO)

Parametric Studio develops STEM software and maker kits designed to teach science, technology, engineering and math to students through hands-on, technology-enabled learning experiences.

ConsumerEdTechHardwareSaaS

PARMedics develops compounds targeting specific molecular pathways to treat chronic pain, asthma, inflammation, and migraines with reduced side effects.

BiotechHealthtechMedical Devices

Scott Boitano(Partner & Co-founder)Theodore Price(Partner & Co-founder)Gregory Dussor(Partner & Co-founder)Josef Vagner(Partner & Co-founder)Kathryn DeFea(CEO)

Pataigin develops diagnostic technology for microbial lipid analysis using mass spectrometry, primarily serving clinical laboratories and healthcare institutions.

BiotechHealthtechMedical Devices

David Goodlett(VP Analytical Chemistry)Robert Ernst(VP Microbiology)Erik Nilsson(CEO)

Perfusion Medical develops PM-208, a patent-protected drug addressing capillary compression in hemorrhagic shock and ischemic conditions.

BiotechHealthtechMedical Devices

PhotoPharmics is a clinical-stage medical device company developing non-invasive, light-based photo-neuromodulation therapies for neurodegenerative disease, with a focus on Parkinson's disease.

BiotechDigital HealthHealthtechMedical DevicesSalt Lake City, US

Kent Savage(Executive Officer, Director)

BoardGCGavin Christensen(Director)inTed Stanley(Director)Daniel Adams(Director)

Co-investorsKIKickstartUPUpStart Ventures

Pneumotactix develops therapeutics and vaccines targeting Streptococcus pneumoniae infections, using approaches including enzymatic capsule degradation and monoclonal antibodies.

BiotechHealthtechMedical DevicesAtlanta, US

Prepped Health develops digital education and patient-engagement tools for healthcare providers and patients facing serious illness, including apps that generate suggested questions for clinical visits and interactive tools teaching about palliative care, hospice, cancer diagnosis, and advance care planning.

Digital HealthHealthtech

Prisms develops VR/AR learning experiences for middle school math and science education, with a focus on teacher professional development and classroom outcomes.

AI & Machine LearningEdTechHardwareSan Francisco, US

AGAnurupa Ganguly(Founder)in

BoardJeffrey Jordan(Director)

Co-investorsANAndreessen HorowitzFIFirst Row PartnersSCScout FundWXWXR FundANAnorak VenturesAVAvalanche VC

Platform for high-throughput material property simulation based on quantum mechanics.

Cambridge, US

Toru Shiozaki(CEO and Co-Founder)

BoardGuanhua Chen(Director)Garnet Chan(Chief Visionary Advisor and Co-founder)

Co-investorsABAbies VenturesEMEmbark VenturesKYKyoto University Innovation CapitalUTUTokyo Innovation Platform Co. Ltd.2X2xN

Quicksilver Biosciences is developing a CMOS-integrated biosensor platform that uses proprietary sensing techniques to reach higher sensitivity in a portable, lower-cost form factor.

BiotechDeep TechSemiconductorsNew York, US

Co-investorsKAKairos Venture Investments, Llc

Radiation Emergency Services provides simulation-based training, exercise support, and planning expertise for radiological and nuclear emergency response organizations worldwide.

Deep TechDefense TechEdTechGovTechSaaS

Wendy Renno(Founder and President)

RadioMedix is a biotechnology company developing targeted radioactive diagnostic and therapeutic agents for oncology, focusing on radiopharmaceuticals and precision imaging in nuclear medicine.

BiotechHealthtechMedical DevicesTexas, US

Ebrahim S. Delpassand, MD(Founder & Chairman of the Board / CEO)Izabela Tworowska, Ph.D, MS.Pharm(Chief Scientific Officer & Co-Founder)Azar Delpassand, RN, BSN(Board Member & Co-Founder)

RadTran develops technology to extract and produce radioactive isotopes (Ra-224 and Ac-225) from naturally occurring thorium for use in targeted alpha therapy cancer treatments.

BiotechDeep TechEnergyHealthtechMedical DevicesNew Materials

Saleem Drera(Chief Executive Officer & Founder)Andy Edwards(Chief Technical Officer)

Rhaeos develops FlowSense, a noninvasive wireless wearable skin patch that monitors fluid flow in the body, initially targeting hydrocephalus patients who depend on implantable shunts for cerebrospinal fluid management.

HardwareHealthtechMedical DevicesEvanston, US

Dr. Chad WebbJAJohn A. Rogers(Executive Officer, Director)RGRoozbeh Ghaffari(Director)inALAnna Lisa Somera(Executive Officer)inChad Seaver(Director)R. Chad Webb(Executive Officer, Director)

Co-investorsCRCreative VenturesPOPortal InnovationsSTSteele Foundation for HopeLALateral Capital

RNet Tech develops computational tools for biomedical research and diagnostics.

AI & Machine LearningBiotechCloud ComputingDeep TechDefense TechMedical DevicesDayton, US

Savage Medical is developing a solution aimed at improving care for patients undergoing colorectal surgery.

HealthtechMedical Devices

Sensit Ventures develops and sells custom miniaturized MEMS chemical sensors that detect specific chemicals in the air and transmit data wirelessly.

AgTechDeep TechHardware

Tom Turpen(President & CEO)in

Ship of Theseus is a therapeutics company developing biologics based on the homeobox (HOX) family of transcription factors.

BiotechHealthtech

Silverbills is a US-based bill payment service where dedicated concierges receive, review, negotiate, and pay clients' bills on time.

ConsumerFintech

Co-investorsGAGaingelsGEGener8tor

SINTX develops advanced ceramic technology solutions for biomedical, aerospace, defense, and energy industries.

BiotechDeep TechDefense TechEnergyMedical DevicesNew Materials

Co-investorsGRGRA Venture

SNJ Pharma is developing SNJ101, a plasmin-independent thrombolytic agent for the treatment of thrombotic disorders.

BiotechHealthtech

Sparian Biosciences is a biotech company developing novel therapeutics for pain and substance use disorders, with a focus on compounds derived from opiate receptor biology research.

BiotechDigital HealthHealthtechLongevityMedical DevicesNew York City, US

Jeff Reich(Co-founder, MD)Gavril Pasternak(Co-founder, MD, PhD)Dr. Amitabh Majumdar(Scientific Co-founder)Dr. Pan(Scientific Co-founder)

Springbok Analytics uses MRI data to measure individual muscle volume, fat infiltration, and symmetry at the individual-muscle level with pixel-level precision.

AI & Machine LearningHealthtechSports TechCharlottesville, US

Joe H(Founder)

Co-investorsALAlumni VenturesANAnthropy PartnersCACartan CapitalTITitletownTech

StemCultures develops microencapsulation technology products for controlling growth factors in cell cultures, serving researchers working with stem cells, primary tumor cells, and organoids.

BiotechDeep TechHealthtechMedical Devices

Sally Temple(Co-founder)Jeff Stern(Co-founder)

SygnaMap uses spatial omics and AI-driven computational pathology to identify molecular biomarkers that map disease pathways, guide therapeutic targets, and monitor disease activity for rare and common diseases.

AI & Machine LearningBiotechDigital HealthSan Antonio, US

Synbal is a biotech company using a proprietary "Active Genetics" gene-editing platform developed at UC San Diego to create humanized transgenic mouse and rat laboratory models expressing multiple human genes.

BiotechDeep TechSan Diego, US

Valentino Gantz(Board Member & Founder)Ethan Bier(Board Member & Founder)

TheraBionic develops a tumor-specific radiofrequency medical device (P1) for cancer treatment, administered non-invasively via a metal spoon applicator on the tongue.

BiotechDeep TechHealthtechMedical DevicesDetroit, US

Boris Pasche(CEO, Board Chair, Co-Founder)Alexandre Barbault(Co-Inventor)Valerie Pasche(Chief Operating Officer)Stefan Grant(General Counsel)

Thermogenesis manufactures cryopreservation and cell processing systems for cord blood banking and cellular therapy applications in the biotechnology and healthcare sectors.

Advanced ManufacturingBiotechHealthtechMedical DevicesRancho Cordova, US

Toi Labs manufactures an AI-enabled toilet seat system that monitors and reports on waste patterns and health indicators for senior living communities and consumers.

AI & Machine LearningHardwareHealthtech

VKVik Kashyap(Founder)in

Co-investors3L3Lines Venture CapitalPOPortfoliaSCScaleGood Fund LP (powered by TELUS)FRFreestyle Capital

BiotechCambridge, US

Shawn Marcell(Executive Officer, Director)BLBen Linden(Executive Officer)inDavid Yu Zhang(Director)Peng Yin(Director)

BoardAdam Wiechhaus(Director)

Co-investorsILIllumina VenturesNONorthpond Ventures

Tradewind BioScience translates research discoveries into novel cancer therapeutics.

BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US

TAThaddeus Allen(CEO)in

Co-investorsY Y Combinator

Trialus Bioscience provides protein purification products and services for laboratory and research applications.

BiotechDeep TechBirmingham, US

Robert Shufflebarger(Chief Executive Officer of the Issuer)

Co-investorsINInnovation Depot

Tybrhealth develops the B3 GEL™ System, a protective gel applied during tendon and ligament repair surgery to reduce post-operative scar formation and preserve tissue mobility.

BiotechHealthtechMedical DevicesHouston, US

TKTim Keane(Founder)inASAlex Smith(Founder)inJeffrey Tyber(Director)PAP. Alex Smith(Founder)inSRStephen Ramon(Executive Officer)inTimothy J. Keane, Jr.(Executive Officer, Director)

Co-investorsARArieal Southeast Angel PartnersASAsymmetry VenturesEIEight CapitalVEVentureSouqY Y CombinatorMEMEDA Angels+2 more

Cyclarity Therapeutics (formerly Underdog Pharmaceuticals) develops drugs based on cyclodextrin compounds that aim to treat and reverse atherosclerosis by removing non-degradable cholesterol and arterial plaque from cells in artery walls.

BiotechHealthtechLongevity

Unify Medical develops advanced vision and imaging systems for the surgical market, including work in multimodal imaging, augmented reality, and 3D computer vision for the operating room.

HardwareHealthtechMedical DevicesCleveland, US

Francis Papay(Co-Founder)Yang Liu(Co-Founder & CTO)inDCDouglas Carroll(President & CEO)inArt Bailey(Chief Operating Officer)inRichard L. Kovach(Executive Officer)

Vectech develops AI-powered vector identification and surveillance technologies to support public health interventions and targeted mosquito control during disease outbreaks.

AI & Machine LearningBiotechData & InfrastructureGovTechHealthtechBaltimore, US

TFTristan Ford(Co-founder + CEO)inMGMeg Glancey(Co-founder + Advisor)inAGAutumn Goodwin(Co-founder + Chief Technology Officer)in

Co-investorsTETechstars

Versametrics develops automated testing equipment for electronic devices that addresses limitations of traditional instruments like source-measurement units.

AI & Machine LearningDeep TechHardwareSaaSSemiconductorsDurham, US

Dr. Steven Noyce(CEO)Jay Doherty(CTO)Dr. Aaron Franklin(Scientific Director)

Viora Health provides a technology-enabled, evidence-based lifestyle change and wellness program that engages diverse and remote patient populations at home through AI-driven behavioral, nutrition, and exercise counseling plus social support.

AI & Machine LearningDigital HealthWellness & Fitness

Deboleena Dutta(Founder and CEO)in

Co-investorsLILighthouse Network Ventures Llc

Vivacelle Bio develops phospholipid nanoparticle therapies (VBI-S and VBI-1) that restore intravascular volume and redirect excess nitric oxide to treat hypovolemia in patients with septic shock or severe blood loss.

BiotechHealthtechMedical DevicesChicago, US

COCuthbert Ormand Simpkins(Executive Officer, Director)DSDiane Simpkins(Co-Founder & Treasurer, Board of Directors)inConrad Epting(Founding Member / Scientific Consultant)inHDHarven DeShield(Executive Officer, Director)inPPaul(CEO/CFO)SNStephen N. Keith(Former CEO)in

Co-investors2F2Flo Ventures

VRx Medical develops web-based AR, VR, and mixed-reality therapies for pain, anxiety, and mental health, including an illusion-therapy experience for arthritis pain relief and a VR surgical simulator for robotic hysterectomy training.

Digital HealthMedical DevicesMental Health

Workit Health is a 100% online addiction treatment program that prescribes FDA-approved medications like Suboxone and naltrexone for opioid, alcohol, and kratom use disorders via licensed clinicians through video consultations.

Digital HealthHealthtechAnn Arbor, US

LMLisa McLaughlin(Executive Officer, Director)inRMRobin McIntosh(Executive Officer, Director)in

BoardTKTodd Kimmel(Director)in

Co-investorsCVCVS Health VenturesIDID VenturesLULux CapitalRRRRE VenturesWAWakestream Ventures3L3L Capital+6 more

HealthtechAlston, US

Brian Chang(Director)Jayon Wang(Mr. Wang is President of the Issuer.)Steven Keller(Director)

Co-investorsGOGood Growth Capital

Relay Response is developing a modern, evidence-based CPR training experience aimed at making CPR readiness accessible to everyone.

EdTechHealthtech

Zaiput Flow Technologies, an MIT spin-out, makes liquid-liquid and liquid-gas separators, back pressure regulators, and multi-stage extraction platforms for continuous flow chemistry.

Advanced ManufacturingDeep TechEnterprise SoftwareHardware

BiotechPhiladelphia, US

Daniel Mazzucco(Executive Officer, Director)Rugart Eric(Executive Officer, Director)

BoardLouis Berardi(Director)

Co-investorsBEBen Franklin Technology PartnersBRBroad Street AngelsRORowan Innovation Venture Fund