Affect Therapeutics
New York, US · Founded 2020 · Delaware corporation · 162 employees on LinkedIn · 11 known investors
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Affect Therapeutics operates an app-based digital treatment provider offering care for substance use disorders (alcohol, cannabis, opioid) and mental health conditions like depression and anxiety, using methods such as contingency management, CBT, medication-assisted treatment, and peer support. It serves members across the U.S. including those covered by Medicaid, and works with providers, courts, employers, and health systems.
Founders & leadership
Affect Therapeutics was founded in 2020 by Jeff DeFlavio.

Board


Investors · 11
How we know: Artis Ventures's portfolio page · the company's own site · funding news · globenewswire.com · Not right? Tell us
How we know: the company's own site · the VCSheet dataset · open dataset · 5k.vc investor directory · Not right? Tell us
How we know: the company's own site · board seat on SEC Form D · globenewswire.com · Not right? Tell us
How we know: Kapor Capital's portfolio page · open dataset · 5k.vc investor directory · Not right? Tell us
How we know: Samsung Next's portfolio page · globenewswire.com · Not right? Tell us
How we know: What If Ventures's portfolio page · globenewswire.com · the VCSheet dataset · Not right? Tell us
Also in the syndicate · 1
Funding
SEC filings, press & company announcements$24.6M disclosed across 2 of 3 rounds · 2021–2025
- Undisclosed amountSeries BNov 2025
Allumia Ventures (lead)
Source ↗
▶$18.1MraisedJul 2023 · 9 investors · Other Health CareRule 506(b)
- Jeff RinehartDirector
- Kevin RyanDirector
- Jeff DeFlavioDirector
- Stuart PetersonDirector
- Kristin MuhlnerExecutive Officer, Director
- Offering amount
- $18.1M
- Amount sold
- $18.1M
- First sale
- Dec 2022
- Incorporated
- Corporation, Delaware, 2020
- Federal exemptions
- 06b
▶$6.5MraisedSep 2021 · 10 investors · OtherRule 506(b)
- Kevin RyanDirector
- Kristin MuhlnerExecutive Officer, Director
- Jeff RinehartDirector
- Jeff DeFlavioDirector
- Offering amount
- $6.5M
- Amount sold
- $6.5M
- First sale
- Jun 2021
- Incorporated
- Corporation, Delaware, 2020
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Founder mafia
2 people who came through Affect Therapeutics went on to found or lead other companies.
Related companies · 5
Companies working in the same space as Affect Therapeutics.
Non-dilutive funding · 1 SBIR/STTR award
Federal grants — no equity taken| Agency | Phase | Year | Amount |
|---|---|---|---|
| National Institutes of Health (NIH)National Institutes of Health | Phase I | 2021 | $309.4K |
Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.
In the news
Frequently asked questions
- What does Affect Therapeutics do?
- Affect Therapeutics operates an app-based digital treatment provider offering care for substance use disorders (alcohol, cannabis, opioid) and mental health conditions like depression and anxiety, using methods such as contingency management, CBT, medication-assisted treatment, and peer support. It serves members across the U.S. including those covered by Medicaid, and works with providers, courts, employers, and health systems.
- Who founded Affect Therapeutics?
- Affect Therapeutics was founded by Jeff DeFlavio in 2020.
- Who are Affect Therapeutics's investors?
- Affect Therapeutics's investors include Artis Ventures, City Light, AlleyCorp, Gaingels, Kapor Capital, LifeArc Ventures, Mana Ventures, Samsung Next and 2 more.
- How much funding has Affect Therapeutics raised?
- Affect Therapeutics has disclosed $24.6M raised across 2 of its 3 known rounds.
- Where is Affect Therapeutics headquartered?
- Affect Therapeutics is headquartered in New York, US.




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