National Institutes of Health (NIH) — 2016 Investments
305 investments dated 2016 · page 1 of 2 · listed companies and verified rows first · show all
Agenus is a biotechnology company developing cancer immunotherapies, including its lead investigational combination of botensilimab (an anti-CTLA-4 antibody) and balstilimab (a PD-1 inhibitor), known as BOT+BAL.
BiotechHealthtechLexington, US
Garo Armen(Chairman & CEO, Co-founder)Ozer Baysal(Executive Officer)Robert Stein(Executive Officer)Christine Klaskin(Executive Officer)inKaren Valentine(Executive Officer)Steven O'Day(Chief Medical Officer)in
Co-investorsAdvent Life SciencesGrazia Equity GmbHHEALTHCARE ROYALTY PARTNERSOberland CapitalCommodore CapitalInvus+2 more
Arvinas is a biopharmaceutical company developing PROTAC protein degrader therapies, with a pipeline focused on oncology and neurology.
BiotechHealthtechNew Haven, US
Sean Cassidy(Executive Officer)inManuel Litchman(Executive Officer, Director)inRandy Teel(President and Chief Executive Officer; Director)inCraig Crews(Founder)
BoardStephen Squinto(Director)inLiam Ratcliffe(Director)in
Co-investors5AM VenturesAccess BiotechnologyCanaan PartnersConnecticut InnovationsNextech InvestRA Capital+3 more
Azitra is a clinical-stage biopharmaceutical company developing genetically engineered bacteria and proteins for treating skin diseases through precision dermatology.
AI & Machine LearningBiotechHealthtechFarmington, US
Francisco D. Salva(President and Chief Executive Officer)inAzim Munivar(Executive Officer, Director, Promoter)
BoardStella Robertson(Director)inTravis Whitfill(Executive Officer, Director, Promoter)in
Co-investorsBios PartnersConnecticut InnovationsKdT VenturesLeaps by Bayer
Context Therapeutics develops clinical-stage T cell engaging bispecific antibody therapies for the treatment of solid tumors.
BiotechHealthtechPhiladelphia, US
Martin Lehr(Founder)inJennifer Minai-Azary(Executive Officer)inAlex Levit(Executive Officer)Linda Beth West(Director)Richard Jay Berman(Director)Philip Kantoff(Director)in
Co-investorsNextech InvestOUP (Osage University Partners)Torrey Pines Investment
Mobia Medical (formerly MicroTransponder) develops Vivistim Paired VNS Therapy, an FDA-approved treatment for stroke survivors with moderate to severe upper extremity impairment.
Digital HealthHealthtechMedical DevicesAustin, US
Richard John Foust(Executive Officer, Director)Frank McEachern(Executive Officer, Director)in
BoardNelson Bunker Curnes(Executive Officer, Director)Thomas Jordan Curnes II(Executive Officer, Director)Casey Tansey(Director)Dana Mead(Director)
Co-investorsLongitude CapitalUT Horizon FundGreen Park & Golf VenturesUS Venture Partners
SAB BIO is a clinical-stage biopharmaceutical company developing multi-specific human immunoglobulin G (hIgG) therapies to treat and prevent immune and autoimmune disorders, using genetically engineered transchromosomic cattle to produce therapeutic candidates.
BiotechDigital HealthHealthtechMedical DevicesMiami Beach, US
Eddie J Sullivan(Founder)inRussell Beyer(Executive Officer)inSamuel J. Reich(Class III Director, Chief Executive Officer)in
BoardJeffrey Spragens(Director)Andrew Moin(Director)Jay Skyler(Director)
Co-investorsJDRF T1D Fund
Vaxcyte is a biotech company developing vaccines to treat or prevent serious infectious diseases.
BiotechDeep TechHealthtechSouth San Francisco, US
Grant Pickering(Chief Executive Officer, Director and Co-Founder)Jeff Fairman(Vice President of Research and Co-Founder)Ashish Khanna(Executive Officer)
BoardTracy Saxton(Director)William Newell(Director)Kurt von Emster(Director)in
Co-investorsAbingworthCTI Life Sciences Fund L.P.Foresite CapitalFrazier Life SciencesJanus Henderson InvestorsLongitude Capital+5 more
3Helix develops and sells collagen hybridizing peptides (CHP) and related conjugates for research and diagnostic applications.
BiotechHealthtechMedical DevicesNew MaterialsSalt Lake City, US
Mike Kirkness(CEO)inToby Barrack(VP)inMichael Fugman(Director)Michael Yu(Director)Noah Nasser(Director)
BoardNalini D Kelly(Director)
Co-investorsUtah Innovation Fund
Abilita Therapeutics is a drug discovery company built on its EMP (Enabled Membrane Proteins) technology, which uses directed evolution to create stability- and expression-enhanced membrane protein variants.
BiotechDeep Tech
Co-investorsTwo Bear Capital
Acpharis develops computational drug discovery software, including computational solvent mapping to identify druggable protein binding sites and protein-protein docking tools tested in CAPRI.
AI & Machine LearningBiotechDeep Tech
Sandor Vajda, Ph.D.(Founder)Dima Kozakov, Ph.D.(Founder)Dmitri Beglov, Ph.D.(CEO)
Acumen Pharmaceuticals is developing treatments for Alzheimer's disease and other neurodegenerative diseases, focusing on understanding and targeting amyloid beta oligomers in neurodegeneration.
BiotechHealthtechLongevityMedical Devices
Daniel O'ConnellinJim Doherty, PhDEric Siemers, MDinMatthew ZugaRussell Barton, MSAmy Schacterle, PhD
Co-investorsK2 HealthVenturesWestern Technology Investment
Adecto Pharmaceuticals develops therapeutic and diagnostic products targeting cancer, with a focus on antibody-based treatments for breast cancer.
BiotechHealthtechMedical DevicesBoston, US
Nora D. Mineva(Co-founder, CEO & CSO)Gail E. Sonenshein(Co-founder & President)Mathilde Romagnoli(Co-founder & Advisor - Strategic Planning & Scientific Approach)
Adeptrix develops the exoBAMS platform, using antibody-based immunoaffinity capture of extracellular vesicles combined with MALDI mass spectrometry to profile proteins, lipids, metabolites and other molecules from a single blood sample.
AI & Machine LearningBiotechMedical Devices
Vladislav Bergo(Founder)in
Co-investorsFormation Venture Engineering
Advanced Tactile Imaging develops tactile and ultrasound imaging devices for biomechanical mapping of the female pelvic floor to support diagnosis and treatment of women's health conditions.
Digital HealthFemTechHealthtechMedical Devices
Armen Sarvazyan(Co-founder)
BiotechAlbuquerque, US
Federica Pericle(Executive Officer, Director)Joseph Patti(Executive Officer, Director)Ebetuel Pallares(Executive Officer, Director)Faith Charles(Director)Debora E Ramirez(Executive Officer)
BoardWaneta Tuttle(Director)in
Co-investorsTramway Venture Partners
AnaBios generates predictive human data for pharmaceutical drug development, using authentic human cells and tissues from healthy and diseased donors to assess drug efficacy and toxicity before clinical trials.
BiotechDeep TechHealthtechSan Diego, US
Andre Ghetti(Chief Executive Officer)inRichard F. Erdman(Director)Paul Miller(Executive Officer)Jack Reynolds(Executive Officer, Director)Peter Crowley(Director)George Goldsmith(Director)
Co-investorsAmpersandKeiretsu ForumTech Coast Angels
Applied BioMath (now part of Certara) provides Quantitative Systems Pharmacology (QSP) consulting services that combine computational modeling with experimental data to address drug development challenges such as first-in-human dose selection.
AI & Machine LearningBiotechDigital HealthHealthtechWinchester, US
John Burke(Manager)inJoshua Apgar(Manager)Andrew Sutherland(Manager)Vihann Kong(Manager)
BoardPeter Sorger(Manager)
Applied StemCell is a genome engineering platform company that develops proprietary technologies and iPSC expertise to enable safe, scalable integration of large DNA payloads into the mammalian genome for gene and cell-based medicine.
BiotechDeep TechMedical DevicesMilpitas, US
Dolores Baksh(Chief Executive Officer)inRuhong Jiang(Executive Officer, Director)Guoliang Yu(Director)
BoardZhenyu Xiao(Director)
Co-investorsFirst Analysis
BiotechEvanston, US
Joseph R. Moskal(Chief Scientific Officer)Torsten M. Madsen(Chief Marketing Officer)Ashish Khanna(Secretary & Chief Business Officer)Norbert G. Riedel(Chief Executive Officer)
BoardLiam Ratcliffe(Director)Terry P. Gould(Director)
Co-investorsBain Capital Life SciencesFrazier Life SciencesLatterell Venture PartnersLongitude CapitalOUP (Osage University Partners)Agent Capital+4 more
Aruna Bio develops a proprietary neural exosome platform and a lead therapeutic neural cell-derived exosome, AB126, designed to cross the blood-brain barrier.
BiotechHealthtechAthens, US
Steven Stice(Chief Scientific Officer and Director)inHarold W. Ingalls(Chief Financial Officer and Director)Tracey Stice(Chief Operating Officer and Secretary)
BoardJohn F. Mangan, Jr.(Director)C. William Griffin(Director)Russell C. Lindner(Director)
Co-investorsEshelman Ventures, LLCEvolution VC PartnersGRA Venture
Cognitopia offers web-based self-management and executive functioning software used to set goals, track assignments and progress, and maintain communication for individuals in special education, independent living, and employment settings.
Digital HealthEdTechSaaS
Tom Keating(CEO & Founder)
BiotechDoylestown, US
Oren Gilad(Executive Officer, Director, Promoter)in
BoardBernard C. Rudnick(Executive Officer, Director)
Co-investorsKeiretsu Forum
Avery Therapeutics is a biotechnology company focused on developing immunomodulatory biologic therapeutics.
BiotechTucson, US
Jennifer Koevary(Executive Officer)Steven Goldman(Executive Officer)inJordan Lancaster(Chief Executive Officer)in
BoardLawrence Mehren(Director)Emile Nuwaysir(Director)
Co-investorsService Provider Capital
Co-investorsMission Bay CapitalMission Biocapital
AxNano provides systems for capturing, conditioning, and destroying PFAS and other contaminants across waste streams, offering a closed-loop solution that tests, extracts, and eliminates pollutants on-site.
Advanced ManufacturingCleantechClimate TechDeep TechNew Materials
BiotechNew Orleans, US
J. Lowry Curley(Executive Officer, Director)inMichael Moore(Executive Officer)inAlif Saleh(Executive Officer, Director)Benjamin Cappiello(Executive Officer)Jeffrey Silverman(Director)Monica Metea(Executive Officer)
Co-investorsNew Orleans Startup Fund
Azevan Pharmaceuticals is a clinical-stage biopharmaceutical company developing orally bioavailable V1a receptor antagonists targeting vasopressin biology for neuropsychiatric, neurodegenerative, neurodevelopmental, and brain injury conditions.
BiotechHealthtechMedical DevicesMental Health
Neal G. Simon(Chief Executive Officer & Director)
Co-investorsScientific Health Development
Baebies develops multifunctional syndromic diagnostic testing using proprietary digital microfluidics, integrating molecular, immunoassay, chemistry, and coagulation testing into a single compact platform (FINDER) that runs on small-volume samples.
BiotechDeep TechDigital HealthHealthtechMedical DevicesResearch Triangle Park, US
Vamsee Pamula(Executive Officer, Director)in
BoardDennis Sacha(Director)William A. Hawkins(Director)
Co-investorsCharlotte Angel FundDuke Capital PartnersIAG Capital PartnersRex Health VenturesSolas BioVenturesVentureSouth+2 more
BioAtla develops novel monoclonal antibody and cell-based therapeutics for cancer treatment using proprietary platforms including Conditionally Active Biologics (CAB) and Comprehensive Integrated Antibody Optimization (CIAO!).
BiotechHealthtechMedical DevicesSan Diego, US
Jay M. Short(Executive Officer, Director)Richard A. Waldron(Executive Officer)inCarolyn Short(Director)
Co-investorsKeshif VenturesPappas CapitalPfizer Venture InvestmentsHBM Healthcare InvestmentsPappas CapitalPfizer Ventures+1 more
Bionex Pharmaceuticals is a pharmaceutical development company focused on formulating, developing, and commercializing novel topical, transdermal/transmucosal, and implant drug delivery systems.
BiotechDeep TechHealthtechNorth Brunswick, US
BioRealm Research provides research and data analysis services delivered by a transdisciplinary team drawn from research universities and industry.
AI & Machine LearningBiotechHealthtech
A biotherapeutics company developing treatments based on compounds such as abscisic acid (ABA)-enriched fig extract, researched for improving glucose tolerance and insulin sensitivity in pre-diabetic patients.
BiotechDigital HealthBlacksburg, US
BrainXell is a company focused on advancing research and improving patient outcomes through scientific work and services.
BiotechHealthtechMadison, US
Su-Chun Zhang(MD, PhD)Chenfeng Song(Director)Shouming Du(Executive Officer, Director)Xinjun Liang(Director)Ed Baetge(Director)
HealthtechAnn Arbor, US
RONALD FRISBIE(Executive Officer)WILLIAM CLARKE(Director)HANNAH HENSEL(Executive Officer, Director)
Co-investorsCANTILEVER INVESTORSInvest Michigan
Briteseed develops hyperspectral imaging technology integrated into laparoscopic and robotic surgical instruments to provide real-time visualization of critical anatomical structures during surgery.
Deep TechHealthtechMedical DevicesChicago, US
Jonathan Whitney Gunn(CEO)Paul Albert Fehrenbacher(Executive Officer, Director)
Co-investorsGOOSE CapitalTMC Venture FundHyde Park AngelsLightbank
Based in Research Triangle Park, NC
BiotechResearch Triangle Park, US
Lucinda Camras(Executive Officer, Director, Promoter)inRoberto Alfaro(Executive Officer, Director)Ray Krauss(Executive Officer, Director)
BoardRobert Rothman(Director)
Co-investorsCharlotte Angel FundHatteras Venture PartnersInFocus Capital Partners, LLCVCapital
CapeSym manufactures advanced crystal materials for nuclear detection and radiation sensing applications, alongside thermal analysis software and materials consulting services.
Deep TechDefense TechHardwareNew MaterialsSemiconductorsNatick, US
Co-investorsAEON FoundryJDRF T1D Fund
Cell Microsystems develops automated instruments for cellular and molecular workflows used in life science research, including oncology, stem cell biology, and regenerative medicine.
BiotechDeep TechHardwareMedical DevicesDurham, US
Scott McGinnis(President)inNancy Allbritton(Director)Yuli Wang(Director)Matthew Megaro(Director)Gary Pace(Executive Officer, Director)Christopher Sims(Executive Officer, Director)
Co-investorsTelegraph Hill PartnersNC IDEA
CFD Research Corporation develops engineering simulations, advanced prototypes, and innovative designs for aerospace, defense, life sciences, materials, and energy sectors using software and experimental capabilities.
AI & Machine LearningBiotechDeep TechDefense TechEnergyHuntsville, US
CH3 Biosystems develops antibodies, cell lines, enzymes, vectors, and other research tools for studying protein methylation pathways in basic science and clinical laboratory settings.
BiotechDeep TechMedical DevicesWestern New York, US
John M. Aletta(Co-Founder and Director of Research)Elvira Gómez Aletta(Co-Founder)John C. Hu(Team Member)
Chaperone Therapeutics develops therapies targeting protein misfolding diseases, including neurodegenerative and rare conditions, using small molecule drug discovery platforms that enhance natural protein folding mechanisms.
BiotechDeep TechHealthtechMedical DevicesChapel Hill, US
Kalpana Merchant(Executive Officer)Dennis Thiele(Executive Officer, Director)Maria Sippola-Thiele(Executive Officer, Director, Promoter)
Capti ReadBasix is a diagnostic reading assessment for secondary students (grades 3-12) that identifies the root causes of reading difficulties through six individual subtests, benchmark reporting, Lexile measures, and dyslexia risk screening.
EdTechSaaS
CheckUp & Choices offers a digital, evidence-based program for people looking to change their relationship with alcohol, using assessments and cognitive behavioral exercises to support moderation or abstinence.
Digital HealthMental HealthWellness & Fitness
ChemoSen3D develops 3D cell culture and diagnostic technology platforms.
BiotechDeep TechHealthtechMedical Devices
Glauco Souza(Co-Founder, Director)Thomas C. Killian(Co-founder)Robert RaphaelDavid Lee
CivaTech Oncology develops polymer-encapsulated low dose rate brachytherapy devices—including CivaSheet, CivaString, and CivaDerm—used by radiation oncologists to deliver targeted radiation therapy for solid tumors such as prostate, pancreatic, and skin cancers.
BiotechHealthtechMedical DevicesDurham, US
Suzanne Troxler Babcock(Executive Officer, Director)
BoardCarlton Midyette(Director)Robert J. Greczyn, Jr.(Director)Delwin Coufal(Director)Tempe Lampe(Director)
Collaborations Pharmaceuticals develops software and conducts drug discovery research for biotech, pharma, animal health, and agrochemical companies.
AI & Machine LearningBiotechDeep TechSaaS
Sean Ekins(Founder, Chief Executive Officer)
Combinati developed the QuantStudio Absolute Q Digital PCR System, which uses microfluidic array plate (MAP) technology for detection and quantification of nucleic acids, rare mutations, and genome editing events.
BiotechDeep TechHardwarePalo Alto, US
Michael Mokelke(Director)Ju-Sung (Paul) Hung(Executive Officer, Director)Charles Collins(Director)
Co-investorsBand of AngelsBayMed Venture PartnersEndurance28IT-Farm Corporation
New Castle, US
Erica Nemser(Executive Officer, Director)inBill Charlton(Executive Officer)Bennett Nemser(Director)
BoardGuido Radaelli(Director)Chris Erickson(Director)Tony Sun(Director)
Co-investorsChevron Technology VenturesGC VenturesPangaea Ventures Us Inc.
Technology-focused company on rational drug design for cancer and chronic inflammatory diseases (acquired by Aclaris Therapeutics in August 2017).
HealthtechSaint Louis, US
Jennifer Bohnert(Executive Officer)inWalter Smith(Executive Officer, Director)Joseph Monahan(Executive Officer, Director)in
BoardDaniel Janiak(Director)Charles Bolten(Director)Thomas Smart(Director)
Co-investorsEpidarex Capital
Covaris manufactures focused-ultrasonicator instruments and cryoextraction systems for sample preparation in research and diagnostics, enabling DNA/RNA shearing, tissue processing, cell lysis, and other laboratory workflows.
BiotechDeep TechHardwareHealthtechMedical DevicesWoburn, US
Creative LIBS Solutions develops analytical instruments based on laser-induced breakdown spectroscopy (LIBS) technology for rapid detection and sample analysis.
Advanced ManufacturingDeep TechHardwareSector Agnostic
Dr. David Cremers(Founder)Dr. Rosalie Multari(Founder)Ann Nelson(Founder)
Curi Bio provides a preclinical drug development platform combining 3D human tissue models of disease (cardiac and skeletal muscle), biosystems for functional analysis, and AI/ML-based insights to assess drug safety, efficacy, and potency.
AI & Machine LearningBiotechMedical Devices
Elliot Fisher(Cofounder)in
Co-investorsDynamk Capital
BiotechSalt Lake City, US
Robert Armstrong(Director)John Kozarich(Director)Joseph Sorenson(Director)Lloyd Czaplewiski(Director)J. Flagg Flanagan(Director)Richard McKoewn(Director)
BiotechAndover, US
Sheila DeWitt(Executive Officer, Director)in
BoardAnthony W. Czarnik(Director)
Diamir Bio develops minimally invasive molecular diagnostic solutions for early detection and monitoring of neurological conditions such as mild cognitive impairment and Alzheimer's disease.
BiotechDigital HealthHealthtechMedical Devices
DiaVacs is a biotechnology company developing cell-based immunotherapies, focused on tolerogenic dendritic cell approaches for Type 1 diabetes and applications related to SARS-CoV-2.
La Jolla, US
Alan Lewis, Ph.D.(President and CEO)
BoardAlexander Casdin(Director)James Gavin(Director)Edwin Naylor(Director)Daniel Bradbury(Executive Officer, Director)Alan Lewis(Director)
Co-investorsBlackbird Ventures
Dimagi provides CommCare, a digital platform for frontline workers that combines data collection with job aids, decision support, referrals, training, and client messaging, plus SureAdhere for remote treatment support.
Digital HealthGovTechImpact & Social GoodSaaSCambridge, US
Vikram Kumar(Founder & Chief Medical Officer)inJonathan Jackson(Co-Founder & CEO)inNeal Lesh(Executive Officer)inClayton Sims(Executive Officer)inCarter Powers(Executive Officer)inScott Mahar(Director)
Co-investorsSteele Foundation for Hope
Doxy.me is a HIPAA-compliant telehealth platform that enables healthcare providers to conduct virtual patient visits through a simple browser-based interface requiring no downloads or passwords.
Digital HealthHealthtechSaaS
Brandon Welch(Founder and CEO)Dylan Turner
Dynavax is a commercial-stage biopharmaceutical company that develops and commercializes vaccines against infectious diseases using its adjuvant technology.
BiotechHealthtechDüsseldorf, DE
Ryan Spencer(Chief Executive Officer)inDavid Novack(President and Chief Operating Officer)inRobert Janssen(Chief Medical Officer and Senior Vice President, Clinical Development)inKelly MacDonald(Chief Financial Officer)inJeff Coon(Chief Human Resources Officer)Donn Casale(Chief Commercial Officer)in
Co-investorsBain Capital Life SciencesHealthCapSanderling Ventures
Eden Park manufactures wafer-thin Far-UVC 222nm technology panels that continuously disinfect air and surfaces to reduce viruses and bacteria in populated spaces.
CleantechHardwareHealthtechChampaign, US
James Garry Eden(Director)Sung-Jin Park(Executive Officer)inRon van Os(Executive Officer)inJeffrey Bulson(Executive Officer)Cyrus Herring(Executive Officer)John Regan(Executive Officer, Director)in
Co-investorsIllinois Ventures
Emmyon develops natural feed additives derived from fruits and vegetables to promote muscle growth and improve feed efficiency in livestock and aquaculture.
AgTechAI & Machine LearningBiotechFoodTechHealthtechLongevityMedical Devices
Enable Biosciences develops ultrasensitive antibody detection assays based on its Antibody Detection by Agglutination-PCR (ADAP) technology for diagnosing conditions including type 1 diabetes, celiac disease, food allergy, Lyme disease, and Zika/dengue.
BiotechDigital HealthHealthtechMedical DevicesBay Area, US
Carolyn Bertozzi(Co-Founder and Chair, SAB)Jason Tsai(Co-Founder and Chief Technology Officer)inPeter Robinson(Co-Founder and Chief Operating Officer)inDavid Seftel(Co-Founder and Chief Executive Officer)inDavid Seftel, MD, MBAin
Co-investorsStartX
BiotechBoston, US
Jeffrey D. Wager(Executive Officer, Director)Daniel Hartman(Director)Roberto Guttmann(Director)Dennis Ausiello(Director)
San Diego protein-sequencing company behind the ProteoCode platform; ceased operations in late 2025.
Co-investorsARCH Venture PartnersDecheng CapitalAlexandriaDeerfield Management CompanyGV (Google Ventures)Nan Fung Life Sciences+1 more
Energesis is a biopharmaceutical company focused on developing therapies for obesity and metabolic disorders through drug discovery targeting energy metabolism and mitochondrial function.
BiotechHealthtech
Brian Freeman(Chief Executive Officer & President, Co-Founder & Director)Olivier Boss(Chief Scientific Officer, Co-Founder & Director)Jean-Paul Giacobino(Scientific Advisory Board & Co-Founder)
EpiVax works with biologic and vaccine developers to assess and manage immunogenicity risk across the product lifecycle, combining in silico analysis with in vitro testing to produce actionable immunogenicity data.
AI & Machine LearningBiotechHealthtech
Annie De Groot MD(Founder)inRich-Henry Schabowsky, PhD, JDin
Co-investorsSV Health Investors
MindFind develops visuotactile measures using eye tracking and machine learning to assess mental functioning, producing reports intended to guide clinical interventions for patients recovering from brain injury and other causes of mental dysfunction.
AI & Machine LearningDigital HealthMedical Devices
Forge Therapeutics operates a drug discovery platform focused on developing medicines that target human metalloenzymes.
BiotechDeep Tech
Co-investorsMC Healthcare VenturesAlexandria
Gaia Medical Institute develops BrainGuardian, a rapid saliva-based test for traumatic brain injury detection that replaces traditional imaging and blood draws.
BiotechDigital HealthHealthtechMedical Devices
Dr. Southern(Founder & CEO)Dr. Peacock(Co-founder)Dr. Hanson(Co-founder)Mr. Lee(President)
HealthtechSan Diego, US
Xiao-Chang Dai(Director)Li Shen(Executive Officer, Director)Kenneth Fong(Director)
Image Analyst MKII is a microscopy image analysis platform for visualizing and measuring biological parameters, with interactive protocols and drag-and-drop pipelines for tasks such as cell counting, cytometry, high content analysis, and ion concentration and membrane potential time courses.
AI & Machine LearningBiotechDeep Tech
Akos Gerencser
Gfree Bio provides computational chemistry and drug design services for pharmaceutical discovery, supporting drug discovery programs across multiple companies.
AI & Machine LearningBiotechDeep Tech
Chuck Reynolds, PhD(Founder)
GlucoSentient develops diagnostic assays based on functional DNA (DNAzymes and aptamers) and nanomaterials for sensing applications.
BiotechDigital HealthMedical Devices
Yi Lu(Founder & Scientific Advisor)Tian Lan(Technical Lead)Steve Mayer
Co-investorsSerra Ventures
HealthtechChandler, US
David Smith(Executive Officer)inBill Colston(Executive Officer, Director)in
BoardCraig Asher(Director)Caren Masen(Director)Carolyn Compton(Director)Paul Conley(Director)
Co-investorsThird Point VenturesVital Venture Capital
Hsiri Therapeutics is a biotech company discovering and developing therapies for drug-resistant bacterial and fungal infections, with focus areas in tuberculosis, non-tuberculous mycobacterial (NTM) diseases, and drug-resistant fungal pathogens.
BiotechHealthtechMedia, US
William Claypool(President & CEO)Ivan Joseph(Chief Financial Officer)
Humanetics is an advanced clinical-stage pharmaceutical company developing drugs to protect and treat injuries from radiation, chemical, and biological threats.
BiotechDefense TechHealthtechMedical DevicesMinnesota, US
Colin Chinn(Chief Medical Officer)
Iaterion is a biopharmaceutical company developing small-molecule drugs for women's health and cancer indications.
BiotechFemTechHealthtechMedical DevicesBerkeley, US
Isaac Cohen(CEO)Dale Leitman(Chief Scientific Officer)
iHealthScreen offers iPredict, an AI-based system that analyzes retinal images captured by a medical assistant to diagnose eye disease status and generate diagnostic reports with referral recommendations.
AI & Machine LearningDigital HealthMedical Devices
Impel Pharmaceuticals develops therapies for diseases with high unmet medical needs by pairing established drugs with its proprietary upper-nasal drug delivery technology.
BiotechHealthtechMedical DevicesSeattle, US
John D. Hoekman(Executive Officer, Director)in
BoardMichael Hite(Director)Stewart Parker(Director)
Co-investors5AM VenturesB Capital GroupvenBio Global StrategicvenBio PartnersWestlake Village BioPartners
Inhibikase Therapeutics is a clinical-stage pharmaceutical company developing protein kinase inhibitor therapeutics for pulmonary arterial hypertension (PAH).
BiotechHealthtechAtlanta, US
Milton H. Werner Ph.D(Executive Officer, Director)inJoseph Frattaroli, C.P.A.(Executive Officer)Dennis Berman(Director)Gisele Dion(Director)
BoardPaul Grint, M.D.(Director)Roy Freeman M.D.(Director)
Co-investorsRA Capital
InnAVasc develops a vascular access graft for hemodialysis, featuring self-sealing pods and puncture-resistant backplates that guide dialysis needle placement to reduce needle-injury and bleeding complications.
BiotechHardwareHealthtechMedical DevicesDurham, US
Shawn Gage(Executive Officer)Jeffrey Lawson(Executive Officer, Director)Joseph Knight(Executive Officer, Director)Roberto Duane Manson(Executive Officer)
BoardDani Bolognesi(Director)
Co-investorsArieal Southeast Angel PartnersDuke Capital PartnersHatteras Venture Partners
An R&D firm that commercializes engineered technologies and research into market-ready solutions addressing real-world problems.
Deep TechDefense TechMedical DevicesNew MaterialsTorrance, US
Dr. Kisholoy Goswami(Cofounder)Uma Sampathkumaran(Senior Vice President of R&D)
Invenio develops rapid on-site tissue imaging systems combined with AI to improve cancer patient care.
AI & Machine LearningBiotechDeep TechMedical DevicesSanta Clara, US
Jay Trautman(President & CEO, Co-Founder)inChris Freudiger(Chief Technology Officer, Co-Founder)inXiaoliang Xie(Director)
BoardDoug Crawford(Director)in
Co-investorsBerkeley CatalystMission Bay CapitalMission Biocapital
Io Therapeutics develops small molecule retinoid drugs, including IRX4204 and IRX5183, as potential treatments for oncology, neurologic, autoimmune, and dermatologic conditions such as psoriasis.
BiotechHealthtechSpring, US
Roshantha A. Chandraratna(Executive Officer, Director)Rosh Chandraratna(Co-founder, initial President & Chief Scientific Officer)Martin Sanders, M.D.(Executive Chairman and CEO, co-founder)Vidyasagar (Sagar) Vuligonda, Ph.D.(Director and Chief Science Officer, co-founder)Rosh Chandraratna, Ph.D(Co-founder and initial President and Chief Scientific Officer)Sharon Lew(Executive Officer)
Voxello develops the noddle, a plug-and-play system that detects patients' small voluntary gestures via sensors so impaired or disabled patients can summon caregivers and operate nurse call systems and speech-generating devices.
Digital HealthHardwareHealthtechMedical DevicesIowa, US
Richard Hurtig(Chief Scientific Officer)Vince HahnBen BerkowitzZihan ZhuBlake Martinson
IQ Proteomics is a contract research organization (CRO) providing quantitative, proteome-wide mass spectrometry services, including drug target identification, chemoproteomics, protein-protein interaction profiling, and custom targeted assays.
BiotechDeep TechHealthtechBoston, US
Decode operates a platform that unifies multiomic, clinical, and real-world data with automated analytics and expert configuration to deliver validated R&D findings for precision medicine.
AI & Machine LearningBiotechDigital HealthNashville, US
Charles Floyd Spurlock III(Executive Officer, Director)Julia B. Polk(Executive Officer, Director)in
BiotechCranbury, US
Bo Liang(Executive Officer, Director)Houman Hemmati(Executive Officer, Director)Wei Wang(Executive Officer, Director)John J Baldwin(Director)Tao Du(Director)
BoardQi Zhu(Director)
Co-investorsBioAdvance
JangoBio is a biotechnology company developing regenerative stem cell therapies aimed at aging and age-related diseases by restoring sex hormone balance.
BiotechHealthtechLongevityFitchburg, US
Robert Cramer(Director)William Kohl(Executive Officer, Director)Victor Mohoney(Director)Richard Bowen(Director)Craig S. Atwood(Executive Officer, Director, Promoter)
Jericho Sciences develops small molecule therapeutics targeting chronic viral infections and emerging viruses, with a focus on achieving long-term remission through reduction of persistent viral sources.
BiotechHealthtechMedical DevicesTampa, US
Dr. Heidi Kay(Founder and CEO)inDr. Haitao GuoinDr. Deanna KulpainDr. Marco SchitoinDr. Esther AlegriainDr. Joe Sebastianin
KamTek is a biotechnology company providing sample storage, cryopreservation, and logistics services for biomedical research institutions, government labs, and biopharma companies.
BiotechEnterprise SoftwareHealthtechLogistics & Supply ChainFrederick, US
Karyopharm is a pharmaceutical company developing drugs based on its SINE (Selective Inhibitor of Nuclear Export) technology, with medicines targeting cancers including multiple myeloma and diffuse large B-cell lymphoma.
BiotechHealthtechNewton, US
Stuart Poulton(Executive Officer)inMichael Mano(Executive Officer)inReshma Rangwala(Executive Officer)inRichard Paulson(CEO)inStephen Mitchener(Executive Officer)inMichael Mason(Executive Officer)in
Co-investorsAvoro Capital AdvisorsForesite CapitalHEALTHCARE ROYALTY PARTNERSRA Capital
BiotechSeattle, US
Shawn Iadonato(Executive Officer, Director)inRobert Hedequist(Executive Officer)Pauline Kenny(Executive Officer)inCharles Magness(Director)
Co-investorsKeiretsu ForumPfizer Venture InvestmentsTSVCWellcome Trust
Kypha develops clinical diagnostic tests for immune system biomarkers, particularly complement activity markers, and provides solutions for real-time immune insights across therapeutic areas.
BiotechDeep TechHealthtechMedical DevicesSt. Louis, US
Nick Staten(Executive Officer)inT. Scott Glover(Executive Officer)inPaul K. Olson(Executive Officer, Director)
BoardDavid Smoller(Director)inJames D. Marselis(Director)Peter Reinecke(Director)in
Co-investorsBioGenerator VenturesMissouri Technology CorporationArsenalSerra Ventures
Instem is a SaaS platform provider offering integrated solutions for research organizations across discovery, study management, regulatory submission, and clinical trial analytics in the life sciences sector.
AI & Machine LearningBiotechData & InfrastructureDeep TechHealthtechSaaS
Lena Bio develops bioengineered products for organ and cell culture research, including perfused organ panels, cell culture scaffolds, and specialized research tools for life science laboratories.
BiotechDeep TechDigital HealthHealthtechMedical DevicesAtlanta, US
Cen4ard offers educational and activity kits, reading materials, and training resources, primarily serving individuals with dementia and their caregivers.
Digital HealthEdTechHealthtechMedical DevicesMental Health
Dr. Cameron Camp
Little Sparrows Technologies develops medical devices for newborn care, including the bili-hut portable phototherapy device for treating neonatal jaundice and the bili-ruler jaundice screening tool.
Winchester, US
DONNA BREZINSKI(Founder, CEO)inGARY GILBERT(Founder, COO)
BoardDOUGLAS TRECO(Director)GEORGIA MCGAUGHEY NICHOLLS(Director)FRANCIS KIM(Director)
Lumicell develops a fluorescence-guided intraoperative imaging technology, including its LUMISIGHT optical imaging agent, that illuminates cancerous tissue in the surgical cavity to help surgeons remove residual cancer during procedures such as lumpectomy.
BiotechHealthtechMedical DevicesNewton, US
Jorge Ferrer(Co-Inventor & Chief Scientific Officer)inW. David Lee(Co-Founder)inHoward Hechler(Executive Officer)inMarnie Curbow(Chief Commercial Officer)inJulio Rodriguez(Head of Finance)in
BoardCosimo Fiorenza(Director)
Co-investorsKinled HoldingLaunchCapitalLaunch Capital
Lumitex designs and manufactures specialized lighting solutions for medical devices and industrial applications.
Advanced ManufacturingHardwareHealthtechMedical DevicesStrongsville, US
Peter Broer(President / CEO)inScott Bogard(Executive Officer)in
BoardMaynard Murch(Director)Richard Gridley(Director)Jonathon Adams(Director)Steven Walling(Director)
Nortiva develops the LYNX drug delivery platform, an oral technology designed to provide long-acting, sustained dosing as a replacement for daily pills.
BiotechHealthtechMedical Devices
Lancaster, US
Solomon Luo(Director)Arthur Yang(Director)Caesar Luo(Director)Jeff Yang(Executive Officer, Director)
MandalMed develops protein-based treatments targeting glycobiology and innate immunity to prevent and reverse organ fibrosis, with an initial focus on heart disease.
BiotechHealthtechMedical DevicesSan Francisco, US
Dr. John(President & CEO)Dr. Mounzih(VP, Product Development)
MAX BioPharma develops lipid-based oxysterol drug candidates targeting debilitating and fatal diseases, including bone defects, fibrotic disorders, viral infections, and chronic inflammatory conditions.
BiotechDeep TechLongevityMedical DevicesCalifornia, US
Farhad Parhami(Founder, President, and CEO)Michael E. Jung(Scientific Co-Founder)William Matsui(Scientific Co-Founder)
MediBeacon develops biocompatible fluorescent tracer agents detected by skin sensors for clinical diagnostic applications including kidney function assessment and gastrointestinal permeability measurement.
AI & Machine LearningBiotechHealthtechMedical DevicesSaint Louis, US
Richard Dorshow(Executive Officer, Director)inTerence Stern(Executive Officer)inSteven Hanley(Executive Officer, Director)
BoardSteven Miller(Director)David Present(Director)Cherine Plumaker(Director)
Co-investorsBioGenerator VenturesMissouri Technology CorporationNewlin Investment Company LLC
Micro Sensor Labs develops sensor-based products for healthcare and life sciences, including Sanibit, a hand-hygiene compliance and risk analysis platform to reduce healthcare-associated infections in hospitals, and MagiCyte, a patented technology for detecting and isolating single cells from heterogeneous samples.
BiotechHealthtechMedical Devices
Millar designs and manufactures precision pressure, pH, and electrochemical sensors for medical devices, research, and industrial applications, serving OEM partners and research institutions globally.
Advanced ManufacturingDeep TechHardwareIoTMedical DevicesHouston, US
Huntly MillarBill Hall(Dr.)
BiotechEugene, US
Janis Weeks(Executive Officer, Director)inShawn Lockery(Executive Officer, Director)inMatt Beaudet(Executive Officer, Director)
Co-investorsStarve UpsOregon Venture FundRogue Venture Partners
NeuroEM Therapeutics develops MemorEM, a wearable head device that administers transcranial electromagnetic treatment to treat cognitive decline and Alzheimer's disease.
Deep TechHealthtechMedical DevicesTampa, US
Gary Arendash(Founder & Scientist Emeritus)inChuck Papageorgiou(Chief Executive Officer)in
BoardMitch Larimore(Director)Jonathan Gordon(Director)
Co-investorsBlueLake.vc
Neuroene Therapeutics develops a mitochondrial modulator drug discovery platform to identify clinical candidates for treating neurological diseases caused by mitochondrial dysfunction.
BiotechDeep TechHealthtechMedical Devices
Dr. Chan(Co-Founder and CEO)Dr. Chou(Co-Founder)
New Scale Technologies designs and manufactures miniature motion systems and robotic inspection tools for use in medical devices, smartphone cameras, robotic automation, and precision metrology.
Advanced ManufacturingDeep TechDefense TechHardwareRoboticsVictor, US
David A. Henderson(CEO and Founder)
Nexgenia develops proprietary stimuli-responsive polymer-based reagents for molecular and cellular selection, diagnostics, and immunoassays.
BiotechDeep TechNew MaterialsSeattle, US
Ron Myers(Executive Officer, Director)
BoardSteven Gillis(Director)Charles P. Waite(Director)Martin Simonetti(Director)Stewart Parker(Director)David Urdal(Director)
Co-investorsThe W FundAlliance of AngelsWRF Capital
NovoMedix is a biotech company developing therapies for cancer and fibrosis by leveraging expertise in drug discovery, development, and biomarker identification.
BiotechDeep TechMedical DevicesSan Diego, US
Cathy A. Swindlehurst(Founder & CEO)Kyle W.H. Chan(Cofounder & CSO)
NOVUSON develops biomedical instrumentation and medical devices, serving healthcare organizations and clinical environments.
BiotechDeep TechHardwareHealthtechMedical DevicesBothell, US
Stuart B. Mitchell(CEO, Founder and Chief Science Officer)inFrancesco P Curra(Executive Officer, Director)Christoph E Mack(Executive Officer, Director)
Co-investorsKeiretsu Forum
NuvOx Pharma is a clinical-stage pharmaceutical company developing NanO₂, an oxygen therapeutic drug intended to improve oxygen delivery from lungs to blood and to tissue in order to reverse tissue hypoxia.
BiotechHealthtech
Co-investorsBand of AngelsMEDA AngelsHunniwell Lake Ventures LLCPasadena Angels
Omega Optics develops integrated optical technologies and biosensing solutions, including silicon-based chips and printed photonics for sensing applications in chemical and biological detection.
BiotechDeep TechHardwareIoTNew MaterialsSemiconductorsAustin, US
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.






















































































































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