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Duo Oncology
Pittsburgh, US · Founded 2020 · Delaware corporation · 4 employees on LinkedIn · 3 known investors
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Duo Oncology is a clinical-stage company developing tumor-activated prodrug combinations intended to replace toxic multi-agent chemotherapy with single medicines that concentrate activity in tumors. Its lead candidate, DUO-207, combines gemcitabine and paclitaxel into a single-infusion prodrug positioned as a chemotherapy backbone for use with KRAS inhibitors in solid tumors such as pancreatic, lung, and breast cancer.
Founders & leadership
Duo Oncology was founded in 2020 by SONG LI, JING-ZHOU HOU, and Sam Rothstein.
Board
Investors · 3
Reported raises · per SEC filings
Form D private placements$7M disclosed across 3 rounds · 2021–2025
▶$1.6MraisedAug 2026 · 13 investors · PharmaceuticalsRule 506(b)
- SAM ROTHSTEINExecutive Officer, Director, Promoter
- JING-ZHOU HOUExecutive Officer, Director, Promoter
- STEPHEN THORNEExecutive Officer, Promoter
- SONG LIDirector, Promoter
- STANLEY MARKSDirector
- LUSONG LUODirector
- JOE GATTODirector
- VICTORIA MANAXDirector
- KATHERINE EICHINGERExecutive Officer
- Offering amount
- $3.5M
- Amount sold
- $1.6M
- Minimum investment
- $25K
- Proceeds to insiders
- $200K
- First sale
- Jun 2025
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$4.3MraisedAug 2023 · 14 investors · PharmaceuticalsRule 506(b)
- JING-ZHOU HOUExecutive Officer, Promoter
- JINGJING SUNPromoter
- SAM ROTHSTEINExecutive Officer, Director, Promoter
- SONG LIDirector, Promoter
- STEPHEN THORNEExecutive Officer, Promoter
- ROBERT ASHLEYDirector
- STANLEY MARKSDirector
- Offering amount
- $4.3M
- Amount sold
- $4.3M
- Minimum investment
- $25K
- Proceeds to insiders
- $150K
- First sale
- Jan 2023
- Incorporated
- Corporation, Delaware, 2020
- Federal exemptions
- 06b
▶$1.1MraisedFeb 2021 · 1 investors · PharmaceuticalsRule 506(b)
- JINGJING SUNPromoter
- SONG LIDirector, Promoter
- STEPHEN THORNEExecutive Officer, Director, Promoter
- JING-ZHOU HOUExecutive Officer, Director, Promoter
- SAM ROTHSTEINExecutive Officer, Director, Promoter
- STANLEY MARKSDirector
- Offering amount
- $1.5M
- Amount sold
- $1.1M
- Proceeds to insiders
- $145K
- First sale
- Feb 2021
- Incorporated
- Corporation, Delaware, 2020
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Related companies · 3
Companies working in the same space as Duo Oncology.
Non-dilutive funding · 1 SBIR/STTR award
Federal grants — no equity taken| Agency | Phase | Year | Amount |
|---|---|---|---|
| National Institutes of Health (NIH)National Institutes of Health | Phase ISTTR | 2023 | $395K |
Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.
In the news
Frequently asked questions
- What does Duo Oncology do?
- Duo Oncology is a clinical-stage company developing tumor-activated prodrug combinations intended to replace toxic multi-agent chemotherapy with single medicines that concentrate activity in tumors. Its lead candidate, DUO-207, combines gemcitabine and paclitaxel into a single-infusion prodrug positioned as a chemotherapy backbone for use with KRAS inhibitors in solid tumors such as pancreatic, lung, and breast cancer.
- Who founded Duo Oncology?
- Duo Oncology was founded by SONG LI, JING-ZHOU HOU, Sam Rothstein in 2020.
- Who are Duo Oncology's investors?
- Duo Oncology's investors include Ulu Ventures, Innovation Works, NuFund Venture Group.
- How much funding has Duo Oncology raised?
- Duo Oncology has disclosed $7M raised across 3 rounds.
- Where is Duo Oncology headquartered?
- Duo Oncology is headquartered in Pittsburgh, US.