Abalone Bio
YC W20San Francisco, US · Founded 2018 · 14 employees · 11 known investors
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Abalone Bio develops target-activating antibodies for difficult-to-drug disease targets by combining engineered biology with machine learning. The company uses large-scale biological measurement platforms and AI-powered sequence analysis to discover functional antibody drugs for pharmaceutical and biotechnology applications.
Also known as Inc
Founders & leadership· Y Combinator alumni (W20)
Abalone Bio was founded in 2018 by Richard Yu and Gustavo Pesce.

Investors · 11
How we know: Freemind Investments's portfolio page · Y Combinator's founder network · Not right? Tell us
How we know: Y Combinator's founder network · gaingels.com · Not right? Tell us
How we know: Y Combinator's founder network · Not right? Tell us
How we know: Harmonix Fund's portfolio page · Y Combinator's founder network · Not right? Tell us
How we know: Jude Gomila's portfolio page · Not right? Tell us
How we know: Metaplanet's portfolio page · the VCSheet dataset · Y Combinator's founder network · Not right? Tell us
How we know: Y Combinator's founder network · pioneerfund.vc · open dataset · 5k.vc investor directory · Not right? Tell us
How we know: the Y Combinator directory · open dataset · 5k.vc investor directory · Not right? Tell us
How we know: Y Combinator's founder network · Not right? Tell us
How we know: the VCSheet dataset · Not right? Tell us
Related companies · 7
Companies working in the same space as Abalone Bio.
Non-dilutive funding · 8 SBIR/STTR awards
Federal grants — no equity taken| Agency | Phase | Year | Amount |
|---|---|---|---|
| National Institutes of Health (NIH)National Institutes of Health | Phase II | 2022 | $2M |
| National Institutes of Health (NIH)National Institutes of Health | Phase I | 2022 | $292.9K |
| National Institutes of Health (NIH)National Institutes of Health | Phase II | 2021 | $2M |
| National Institutes of Health (NIH)National Institutes of Health | Phase I | 2021 | $300.2K |
| National Institutes of Health (NIH)National Institutes of Health | Phase I | 2020 | $349K |
| National Science Foundation | Phase II | 2019 | $750K |
| National Institutes of Health (NIH)National Institutes of Health | Phase I | 2019 | $300K |
| National Science Foundation | Phase I | 2018 | $225K |
Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.
Legal entities · 1
corporate structureFrequently asked questions
- What does Abalone Bio do?
- Abalone Bio develops target-activating antibodies for difficult-to-drug disease targets by combining engineered biology with machine learning. The company uses large-scale biological measurement platforms and AI-powered sequence analysis to discover functional antibody drugs for pharmaceutical and biotechnology applications.
- Who founded Abalone Bio?
- Abalone Bio was founded by Richard Yu, Gustavo Pesce in 2018.
- Who are Abalone Bio's investors?
- Abalone Bio's investors include Freemind Investments, Gaingels, Gravity, Harmonix Fund, Horizons Ventures, Jude Gomila, Metaplanet, Pioneer and 3 more.
- Where is Abalone Bio headquartered?
- Abalone Bio is headquartered in San Francisco, US.


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