/Investor DB

Cowtown Angels

Angel network

Fort Worth · Pre-Seed–Series A · 12 people tracked

Find your way into Cowtown Angels

Sign up to find every way you can get introduced to Cowtown Angels

  • Your email: who you already know at Cowtown Angels, and who your contacts know
  • 2nd- and 3rd-degree connections: people you know who worked, studied or invested with the Cowtown Angels team
  • Your LinkedIn: the connections who can make the intro for you

We rank every route by how warm it is, so you raise on warm intros instead of cold emails.

✨ Fox Verdict
Sign up to see your fit

Investment thesis

Cowtown Angels operates as Fort Worth's leading angel investor network, linking early-stage entrepreneurs with angel capital to help startups scale. Since its founding in 2013, the group has deployed more than $27 million into over 50 portfolio companies, generating nine exits including the $465M acquisition of Encore Vision. Its investments span sectors such as biotech, medical devices, therapeutics, consumer products, and technology. Members evaluate companies for sustainable markets and strong teams, and the network accepts applications from founders seeking funding while welcoming prospective angel investors to join.

Source: firm website, verified Oct 1, 2026.

Stage
Pre-Seed–Series A
HQ
Fort Worth, TX, US
Instruments
Equity
Founded
2013
Tracked investments
61
IPOs
1

Team · 12 people

from the firm's website
Kaison Giles· Program Manager
Pete O'Brien· Co-Vice Chair
Venkata Jasti· Co-Vice Chair

What they invest in

from 26 of 61 portfolio companies

Healthtech ×17Biotech ×12Medical Devices ×11Deep Tech ×6Consumer ×5Digital Health ×4Direct to Consumer ×4Advanced Manufacturing ×3

HQs:United States×22Canada×1

Investments · 61 tracked

founders shown can be your intro path

By year:2025 · 12018 · 12017 · 13 dated

Salarius Pharmaceuticalsdecoytx.comNASDAQ: DCOY

Decoy Therapeutics is a biotechnology company developing Designable Multi-Antivirals (D-MAVs), peptide conjugate antivirals built on its AI-enabled IMP³ACT platform to target viral mechanisms shared across multiple viruses.

AI & Machine LearningBiotechHealthtechHouston, US

Christoph Westphal(Executive Officer, Director)Mark Rosenblum(Executive Vice President, Chief Financial Officer)inDavid Arthur(Chief Executive Officer, President)in

BoardStephen Kraus(Director)Arnold C. Hanish(Director)Jonathan Lieber(Director)

Co-investorsDellin Investments

Corinnovacorinnova.cominJun 2017✓ verified

CorInnova develops a minimally invasive, non-blood contacting cardiac assist device designed to treat acute heart failure patients who cannot use existing solutions.

Deep TechHealthtechMedical DevicesHouston, US

John Criscione(Director)inWilliam Altman(Executive Officer, Director)inDennis Robins(Director)Boris Leschinsky(Executive Officer)Clarice Motter(Executive Officer)Keith Svagerko(Executive Officer)

Co-investorsHouston Angel NetworkKeiretsu ForumTMC Venture FundHarvard Business School Alumni Angels of Greater New YorkWellcome TrustAggie Angel Network+1 more

Altis Biosystemsaltisbiosystems.comin𝕏

Altis Biosystems builds RepliGut®, human intestinal tissue models grown from human intestinal stem cells that provide human-relevant preclinical data for drug absorption, metabolism, toxicity, and disease modeling.

BiotechDeep TechHealthtechMedical DevicesDurham, US

Christopher Sims(Executive Officer)inJimmy Smedley(Executive Officer)inSamuel Franklin(Director)Joseph McMahon(Director)Michael Biron(Executive Officer, Director)

BoardChristopher Perkins(Director)

Co-investorsAtlanta Technology AngelsCentral Texas Angel NetworkCheckmate Capital Group LLCHatteras Venture PartnersIDEA NCJohnson Venture Partners+1 more

Aroviaarovia.com

Arovia manufactures Splay, a portable display device that combines a collapsible screen with ultra-short-throw projection technology for productivity, presentations, and entertainment.

ConsumerDeep TechHardwareNew MaterialsHouston, US

Alex(Co-founder, Optical Engineer)Alexander David Wesley(Executive Officer, Director)inGeorge Shengliang Zhu(Founder)inTaylor Yoke(Executive Officer, Director)Rahul Chandra(Executive Officer)Wesley D Alexander(Executive Officer, Director)

Co-investorsBoot64 VenturesGOOSE CapitalHouston Angel NetworkTexas HALO Fund

Ateiosateios.comin𝕏

Ateios develops electrode manufacturing techniques designed to accelerate production speed, reduce carbon emissions, and decrease the physical footprint of battery manufacturing and gigafactories.

Advanced ManufacturingCleantechEnergyMedical DevicesNew MaterialsLa Jolla, US

Terry Taber(CTO)

Co-investorsCarat Venture PartnersCharmides CapitalE8 AngelsElevate VenturesGood Growth CapitalHG Ventures+6 more

Atticus Pharmaatticuspharma.com

Atticus Pharma develops immunodermatology therapeutics using patented sustained-release technology for enhanced delivery to the viable epidermis.

BiotechHealthtechMedical Devices

Co-investorsAEON FoundryVentureSouth

Austlen Baby Co.austlen.com
Chromis Fiberopticschromisfiber.com𝕏

Chromis Technologies engineers and manufactures custom amorphous fluoropolymers, marketed under the CyclAFlor brand, with tunable optical, chemical, and electrical properties for applications such as semiconductor pellicles, optical coatings, gas separation membranes, and fuel cell ionomers.

Advanced ManufacturingDeep TechNew MaterialsSemiconductorsWarren, US

Whitney White(Chief Technology Officer)inFrank J. Graziano(Chief Executive Officer)inMiri Park(Chief Operating Officer)in

BoardPeggy Wallace(Director)Boying Barry Zhang(Director)Bill Michaels(Director)

Co-investorsBoston Harbor AngelsNew York Angels

Cognition Therapeuticscogrx.comin𝕏

Cognition Therapeutics is a clinical-stage biotechnology company developing zervimesine (CT1812), an investigational once-daily oral small-molecule therapy designed to protect brain synapses by blocking toxic protein oligomers.

BiotechHealthtechPittsburgh, US

Susan Catalano(Executive Officer, Director)inSusan Catalano, Ph.D.(Co-founder)Lisa Ricciardi(Chief Executive Officer)inHarold Safferstein(Executive Officer, Director)

BoardNada Jain(Director)Franz Hefti(Director)

Co-investors3E Bioventures CapitalAtlanta Technology AngelsDolby Family VenturesGolden SeedsHouston Angel NetworkiNetworks

Cx Precision Medicinecxprecisionm.comin

Cx Precision Medicine develops blood-based diagnostic tests for Alzheimer's and other neurodegenerative diseases, delivering precision medicine tools for early diagnosis and personalized treatment in primary care settings.

AI & Machine LearningBiotechDigital HealthMedical DevicesFort Worth, US

Sid O'Bryant(Scientific Founder, Executive Director of the Institute for Translational Research)Frank Gerome(Director, CEO and President)in

EISANA CORPeisana.com

Eisana Health is an early-stage medical device company developing a patient-centered cooling system — including cooling gloves, booties, and a portable chiller — to prevent chemotherapy-induced peripheral neuropathy (CIPN) in cancer patients.

HardwareHealthtechMedical Devices

Carole Spangler Vaughn(Founder)

Encore Vision Inc.encorevisionusa.com

Fort Worth, US

Evelyn Blake(Executive Officer)William R. Burns(Executive Officer, Director)in

BoardLes Kreis(Director)Robert Willard(Director)John Hunkeler(Director)Adrienne Graves(Director)

Co-investorsBios Partners

Evecxiaevecxia.com

Evecxia Therapeutics develops 5-HTP-based drugs using proprietary drug delivery technologies designed to increase brain serotonin production as adjunctive treatments for depression and other mental disorders.

BiotechDigital HealthMental HealthResearch Triangle Park, US

Marc Caron(Executive Officer, Director)Marc Caron, PhD(Founder)Jacob Jacobsen, PhD(Co-Founder & Chief Executive Officer)Jacob Jacobsen(Executive Officer, Director)inDavid Zaccardelli(Director)Roger Jeffs(Director)

Co-investorsEvolution VC PartnersAvAir Investments

Interplay Learninginterplaylearning.comin𝕏

Interplay Learning builds online skilled trades courses designed and delivered by industry experts and instructional designers, covering foundational technical knowledge and real-world applications for technicians.

EdTechEnterprise SoftwareFuture of WorkHR TechSaaSAustin, US

Douglas Donovan(Executive Officer, Director)

BoardIan Chiu(Director)inCharlie Plauche(Director)inRichard Waitumbi(Director)Sam Decker(Director)Kimberly Caldbeck(Director)

Co-investorsCathexis VenturesCentral Texas Angel NetworkCerity Partners Venturesgumi IncOwl VenturesS3 Ventures+7 more

Little Passportslittlepassports.comin𝕏

Little Passports is a direct-to-consumer children's subscription brand that ships monthly activity kits with hands-on projects, stories, stickers, and activity books focused on geography, culture, science, and art.

ConsumerDirect to ConsumerEdTechSan Francisco, US

Amy Norman(Executive Officer, Director)inStella Ma(Executive Officer, Director)

BoardAldo Manzini(Director)inTyler Head(Director)Jennifer Dulski(Director)inSheri Anderson(Director)

Co-investorsAstiaGolden SeedsNext Play Ventures

MOGLmogl.onlinein𝕏

MOGL operates a marketplace and software platform for NIL (name, image, and likeness) deals in collegiate athletics, connecting student-athletes with donors and brands.

Marketing TechMarketplacesSaaSSports Tech

Matthew Himelstein(Chief Product & Technology Officer)inAyden Syal(Co-founder & Chief Executive Officer)inBrandon Wimbush(Co-founder & Advisor)in

Co-investorsAperture Venture CapitalEvolution VC PartnersSand Hill AngelsChaos VenturesIrishAngelsMagarac Venture Partners+1 more

OmniLifeomnilife.healthin𝕏

OmniLife Health develops FlowHawk, a clinical workflow automation platform that helps care teams manage complex care pathways, with initial focus on organ transplant centers.

Digital HealthEnterprise SoftwareHealthtechBeaverton, US

Co-investorsBoston Harbor AngelsDakota Venture GroupKeyhorse Capital

Periosciencesperiosciences.com

VistaApex Solutions is a dental healthcare company formed by uniting the VistaApex, PerioProtect, and PerioSciences brands, offering products such as antioxidant-based oral care, FDA-cleared non-invasive tray therapy for gum disease, and clinical endodontic and operatory materials.

ConsumerDirect to ConsumerHealthtechMedical DevicesWellness & Fitness

Russell Moon(Founder)in

Co-investorsGreen Park & Golf Ventures

Prosoriaprosoria.comin𝕏

Prosoria is an over-the-counter consumer healthcare company that develops pharmaceutical-grade products for chronic health conditions using scientifically-tested formulations.

ConsumerDirect to ConsumerHealthtechWellness & Fitness

Co-investorsHouston Angel NetworkNorth Texas Angel Network

Renervarenerva.comin

Renerva develops implantable medical devices to treat peripheral nerve injuries.

BiotechDeep TechHealthtechMedical DevicesPittsburgh, US

Lorenzo Soletti(LLC Manager)inBryan N. Brown(Chief Technology Officer)inWilliam A Sekkel(LLC Manager)inPeter DeComo(LLC Manager)J. Christopher Flaherty(Executive Vice President for Intellectual Property)Paul A Gardner(Chief Medical Officer)

Sagemedicsagemedic.com

SageMedic is a California-licensed clinical laboratory providing cancer treatment testing and diagnostics through its SAGE Oncotest™ platform.

BiotechHealthtechMedical Devices

Chris Apfel(Founder, CEO & Chair)inBrigitte Apfel(Co-Founder, Treasurer)

Co-investorsKeiretsu Forum

Salariussalariuspharma.com

Decoy Therapeutics is a biotechnology company developing Designable Multi-Antivirals (D-MAVs), peptide conjugate antivirals built on its AI-enabled IMP³ACT platform to target viral mechanisms conserved across multiple viruses.

AI & Machine LearningBiotechHealthtech

Co-investorsCentral Texas Angel NetworkDellin Investments

Stream Biomedicalstreambiomedical.com

Stream Biomedical is a clinical-stage biotechnology company developing LG3, a biologic derived from a natural repair protein intended to protect and restore the brain by activating its repair systems.

BiotechDeep TechHealthtechHouston, US

H. Davis Adkisson(Chief Scientific Officer)inChris Garabedian(Director)William Schwieterman(Board of Directors)Fred Callori(Director)

BoardAmanda De La Garza(Director)in

Co-investorsBios Partners

True Made Foodstruemadefoods.comin

True Made Foods makes no-sugar condiments—including ketchup, BBQ sauces, and rubs—sweetened with fruits and vegetables such as butternut squash, carrots, and apples instead of refined or artificial sweeteners.

ConsumerDirect to ConsumerFoodTechAlexandria, US

Abraham Kamarck(Executive Officer, Director)in

BoardRichard Scheiner(Director)

Co-investorsBlack Jays VenturesCentral Texas Angel NetworkSiddhi Capital

VenoStentvenostent.comin𝕏Seed

SelfWrap develops bioabsorbable wrap materials for vascular grafts that conform to individual patient anatomy and are designed to be absorbed by the body, unlike alloy-based alternatives.

BiotechDigital HealthHealthtechMedical DevicesHouston, US

Tim Boire(Founder)inGeoffrey Lucks(Founder)in

BoardJoel Whitley(Director)inJim Monsor(Director)Robert Crutchfield(Director)in

Co-investorsAlumni VenturesC3 VenturesCreative VenturesGood Growth CapitalHealth WildcattersKube VC+10 more

Vessl Prostheticsvesslpro.comin

Vessl designs adaptive prosthetic technology that adjusts to the body's dynamic changes to provide consistent comfort and natural movement for amputees.

Advanced ManufacturingHardwareHealthtechMedical DevicesWellness & FitnessIlderton, CA

Co-investorsRobin Hood VenturesTechstars

Zylo Therapeuticszylotherapeutics.com

Zylö Therapeutics develops therapeutic delivery technology, focusing on product development in the biotech and drug-delivery space.

BiotechHealthtechGreenville, US

Scott R. Pancoast(CEO & Founder)inCharles E. Hinkle(Chief Financial Officer)inAndrew Draganski(Vice President, Product Development)Thomas Patrick Murray(Executive Officer)Lance Michael White(Director)Gary J Atkinson(Director)

Co-investorsAEON FoundryBoston Harbor AngelsHBS Angels of Boston

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

BimotalBMI Organ BankCAGE Bio Inc.CardioWiseDigital Seat MediaEnsemble OrthopedicsEoseraGale HSAGlidanceGreen Steel EnvironmentalHaxiotIn TUMO TherapeuticsKEYKlinriskMerge Labs, Inc.ModumetalMy Art CacheMyndVRNoninvasixNuvotheraPleiogenixRancho Santa Fe BioRevitalize Charging SolutionsRuby's Naturals, Inc.Smart Human DynamicsSmart Response TechnologiesSolGroStrategic Thermal LabsSurvey LocalTerecircuitsTradeverifydTympanogenZenblen

Exits · 1

1 IPOs

Salarius PharmaceuticalsNASDAQ: DCOY

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Cowtown Angels made?
Cowtown Angels has 61 tracked investments, 1 of which have exited, including 1 dated in the last 24 months.
What stage does Cowtown Angels invest at?
Cowtown Angels invests at the Pre-Seed, Seed, Series A stages.
What sectors does Cowtown Angels focus on?
Cowtown Angels focuses on Biotech, Cleantech, Consumer, Deep Tech, Healthtech, Medical Devices, New Materials, SaaS, Sector Agnostic.
Where is Cowtown Angels located?
Cowtown Angels is headquartered in Fort Worth, US.

Images

Cowtown Angels photo

Similar investors

AirTree Ventures

AirTree Ventures runs Pathfinders, a free four-week in-person program in Sydney for young builders (high-school graduates up to age 23) to work on a real product, access the AirTree team and founders, and build a peer network.

$132K – $16.5M
B Capital Group

B Capital is a global investment firm backing early to late-stage technology innovators across technology, healthcare, and energy & resilience sectors.

$10M – $50M
Balderton Capital

Balderton Capital is a European venture capital firm that backs technology startups.

$5M – $50M
CRV (Charles River Ventures)

CRV is a venture capital firm that backs founders at the seed and Series A stages, focusing on those with deep conviction and unique insights.

$250K – $5M
Cherubic Ventures

Cherubic Ventures is known for investing before a startup even launches or reaches product-market fit, often as the first institutional investor, while also setting aside half of its latest fund for follow-on support all the way through pre-IPO; it was also one of the first venture firms to operate as a solo general partner and has grown into one of the largest funds run that way. Founded by Matt Cheng, who previously built two companies that each reached over $1 billion in public market value, the firm was designed from the start to invest across both the U.S. and Asia, backing early breakout companies in places like Croatia, Bangladesh, Japan, and Taiwan in addition to the U.S., with its Taipei roots still central to its identity alongside its Silicon Valley presence.

$220K – $27M

Featured in lists