Cowtown Angels
Angel networkFort Worth · Pre-Seed–Series A · 12 people tracked
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Investment thesis
Cowtown Angels operates as Fort Worth's leading angel investor network, linking early-stage entrepreneurs with angel capital to help startups scale. Since its founding in 2013, the group has deployed more than $27 million into over 50 portfolio companies, generating nine exits including the $465M acquisition of Encore Vision. Its investments span sectors such as biotech, medical devices, therapeutics, consumer products, and technology. Members evaluate companies for sustainable markets and strong teams, and the network accepts applications from founders seeking funding while welcoming prospective angel investors to join.
Source: firm website, verified Oct 1, 2026.
Team · 12 people
from the firm's websiteWhat they invest in
from 26 of 61 portfolio companiesHealthtech ×17Biotech ×12Medical Devices ×11Deep Tech ×6Consumer ×5Digital Health ×4Direct to Consumer ×4Advanced Manufacturing ×3
HQs:United States×22Canada×1
Investments · 61 tracked
founders shown can be your intro pathBy year:2025 · 12018 · 12017 · 13 dated
Decoy Therapeutics is a biotechnology company developing Designable Multi-Antivirals (D-MAVs), peptide conjugate antivirals built on its AI-enabled IMP³ACT platform to target viral mechanisms shared across multiple viruses.
AI & Machine LearningBiotechHealthtechHouston, US
Christoph Westphal(Executive Officer, Director)Mark Rosenblum(Executive Vice President, Chief Financial Officer)inDavid Arthur(Chief Executive Officer, President)in
BoardStephen Kraus(Director)Arnold C. Hanish(Director)Jonathan Lieber(Director)
Co-investorsDellin Investments
CorInnova develops a minimally invasive, non-blood contacting cardiac assist device designed to treat acute heart failure patients who cannot use existing solutions.
Deep TechHealthtechMedical DevicesHouston, US
John Criscione(Director)inWilliam Altman(Executive Officer, Director)inDennis Robins(Director)Boris Leschinsky(Executive Officer)Clarice Motter(Executive Officer)Keith Svagerko(Executive Officer)
Co-investorsHouston Angel NetworkKeiretsu ForumTMC Venture FundHarvard Business School Alumni Angels of Greater New YorkWellcome TrustAggie Angel Network+1 more
Altis Biosystems builds RepliGut®, human intestinal tissue models grown from human intestinal stem cells that provide human-relevant preclinical data for drug absorption, metabolism, toxicity, and disease modeling.
BiotechDeep TechHealthtechMedical DevicesDurham, US
Christopher Sims(Executive Officer)inJimmy Smedley(Executive Officer)inSamuel Franklin(Director)Joseph McMahon(Director)Michael Biron(Executive Officer, Director)
BoardChristopher Perkins(Director)
Co-investorsAtlanta Technology AngelsCentral Texas Angel NetworkCheckmate Capital Group LLCHatteras Venture PartnersIDEA NCJohnson Venture Partners+1 more
Arovia manufactures Splay, a portable display device that combines a collapsible screen with ultra-short-throw projection technology for productivity, presentations, and entertainment.
ConsumerDeep TechHardwareNew MaterialsHouston, US
Alex(Co-founder, Optical Engineer)Alexander David Wesley(Executive Officer, Director)inGeorge Shengliang Zhu(Founder)inTaylor Yoke(Executive Officer, Director)Rahul Chandra(Executive Officer)Wesley D Alexander(Executive Officer, Director)
Co-investorsBoot64 VenturesGOOSE CapitalHouston Angel NetworkTexas HALO Fund
Ateios develops electrode manufacturing techniques designed to accelerate production speed, reduce carbon emissions, and decrease the physical footprint of battery manufacturing and gigafactories.
Advanced ManufacturingCleantechEnergyMedical DevicesNew MaterialsLa Jolla, US
Terry Taber(CTO)
Co-investorsCarat Venture PartnersCharmides CapitalE8 AngelsElevate VenturesGood Growth CapitalHG Ventures+6 more
Atticus Pharma develops immunodermatology therapeutics using patented sustained-release technology for enhanced delivery to the viable epidermis.
BiotechHealthtechMedical Devices
Co-investorsAEON FoundryVentureSouth
Chromis Technologies engineers and manufactures custom amorphous fluoropolymers, marketed under the CyclAFlor brand, with tunable optical, chemical, and electrical properties for applications such as semiconductor pellicles, optical coatings, gas separation membranes, and fuel cell ionomers.
Advanced ManufacturingDeep TechNew MaterialsSemiconductorsWarren, US
Whitney White(Chief Technology Officer)inFrank J. Graziano(Chief Executive Officer)inMiri Park(Chief Operating Officer)in
BoardPeggy Wallace(Director)Boying Barry Zhang(Director)Bill Michaels(Director)
Co-investorsBoston Harbor AngelsNew York Angels
Cognition Therapeutics is a clinical-stage biotechnology company developing zervimesine (CT1812), an investigational once-daily oral small-molecule therapy designed to protect brain synapses by blocking toxic protein oligomers.
BiotechHealthtechPittsburgh, US
Susan Catalano(Executive Officer, Director)inSusan Catalano, Ph.D.(Co-founder)Lisa Ricciardi(Chief Executive Officer)inHarold Safferstein(Executive Officer, Director)
BoardNada Jain(Director)Franz Hefti(Director)
Co-investors3E Bioventures CapitalAtlanta Technology AngelsDolby Family VenturesGolden SeedsHouston Angel NetworkiNetworks
Cx Precision Medicine develops blood-based diagnostic tests for Alzheimer's and other neurodegenerative diseases, delivering precision medicine tools for early diagnosis and personalized treatment in primary care settings.
AI & Machine LearningBiotechDigital HealthMedical DevicesFort Worth, US
Sid O'Bryant(Scientific Founder, Executive Director of the Institute for Translational Research)Frank Gerome(Director, CEO and President)in
Eisana Health is an early-stage medical device company developing a patient-centered cooling system — including cooling gloves, booties, and a portable chiller — to prevent chemotherapy-induced peripheral neuropathy (CIPN) in cancer patients.
HardwareHealthtechMedical Devices
Carole Spangler Vaughn(Founder)
Fort Worth, US
Evelyn Blake(Executive Officer)William R. Burns(Executive Officer, Director)in
BoardLes Kreis(Director)Robert Willard(Director)John Hunkeler(Director)Adrienne Graves(Director)
Co-investorsBios Partners
Evecxia Therapeutics develops 5-HTP-based drugs using proprietary drug delivery technologies designed to increase brain serotonin production as adjunctive treatments for depression and other mental disorders.
BiotechDigital HealthMental HealthResearch Triangle Park, US
Marc Caron(Executive Officer, Director)Marc Caron, PhD(Founder)Jacob Jacobsen, PhD(Co-Founder & Chief Executive Officer)Jacob Jacobsen(Executive Officer, Director)inDavid Zaccardelli(Director)Roger Jeffs(Director)
Co-investorsEvolution VC PartnersAvAir Investments
Interplay Learning builds online skilled trades courses designed and delivered by industry experts and instructional designers, covering foundational technical knowledge and real-world applications for technicians.
EdTechEnterprise SoftwareFuture of WorkHR TechSaaSAustin, US
Douglas Donovan(Executive Officer, Director)
BoardIan Chiu(Director)inCharlie Plauche(Director)inRichard Waitumbi(Director)Sam Decker(Director)Kimberly Caldbeck(Director)
Co-investorsCathexis VenturesCentral Texas Angel NetworkCerity Partners Venturesgumi IncOwl VenturesS3 Ventures+7 more
Little Passports is a direct-to-consumer children's subscription brand that ships monthly activity kits with hands-on projects, stories, stickers, and activity books focused on geography, culture, science, and art.
ConsumerDirect to ConsumerEdTechSan Francisco, US
Amy Norman(Executive Officer, Director)inStella Ma(Executive Officer, Director)
BoardAldo Manzini(Director)inTyler Head(Director)Jennifer Dulski(Director)inSheri Anderson(Director)
Co-investorsAstiaGolden SeedsNext Play Ventures
MOGL operates a marketplace and software platform for NIL (name, image, and likeness) deals in collegiate athletics, connecting student-athletes with donors and brands.
Marketing TechMarketplacesSaaSSports Tech
Matthew Himelstein(Chief Product & Technology Officer)inAyden Syal(Co-founder & Chief Executive Officer)inBrandon Wimbush(Co-founder & Advisor)in
Co-investorsAperture Venture CapitalEvolution VC PartnersSand Hill AngelsChaos VenturesIrishAngelsMagarac Venture Partners+1 more
OmniLife Health develops FlowHawk, a clinical workflow automation platform that helps care teams manage complex care pathways, with initial focus on organ transplant centers.
Digital HealthEnterprise SoftwareHealthtechBeaverton, US
Co-investorsBoston Harbor AngelsDakota Venture GroupKeyhorse Capital
VistaApex Solutions is a dental healthcare company formed by uniting the VistaApex, PerioProtect, and PerioSciences brands, offering products such as antioxidant-based oral care, FDA-cleared non-invasive tray therapy for gum disease, and clinical endodontic and operatory materials.
ConsumerDirect to ConsumerHealthtechMedical DevicesWellness & Fitness
Russell Moon(Founder)in
Co-investorsGreen Park & Golf Ventures
Prosoria is an over-the-counter consumer healthcare company that develops pharmaceutical-grade products for chronic health conditions using scientifically-tested formulations.
ConsumerDirect to ConsumerHealthtechWellness & Fitness
Co-investorsHouston Angel NetworkNorth Texas Angel Network
Seattle, US
Ryan Vogel(CEO)in
Co-investorsDakota Venture GroupRobin Hood VenturesRockies Venture ClubSWAN Impact Network
Renerva develops implantable medical devices to treat peripheral nerve injuries.
BiotechDeep TechHealthtechMedical DevicesPittsburgh, US
Lorenzo Soletti(LLC Manager)inBryan N. Brown(Chief Technology Officer)inWilliam A Sekkel(LLC Manager)inPeter DeComo(LLC Manager)J. Christopher Flaherty(Executive Vice President for Intellectual Property)Paul A Gardner(Chief Medical Officer)
SageMedic is a California-licensed clinical laboratory providing cancer treatment testing and diagnostics through its SAGE Oncotest™ platform.
BiotechHealthtechMedical Devices
Chris Apfel(Founder, CEO & Chair)inBrigitte Apfel(Co-Founder, Treasurer)
Co-investorsKeiretsu Forum
Decoy Therapeutics is a biotechnology company developing Designable Multi-Antivirals (D-MAVs), peptide conjugate antivirals built on its AI-enabled IMP³ACT platform to target viral mechanisms conserved across multiple viruses.
AI & Machine LearningBiotechHealthtech
Co-investorsCentral Texas Angel NetworkDellin Investments
Stream Biomedical is a clinical-stage biotechnology company developing LG3, a biologic derived from a natural repair protein intended to protect and restore the brain by activating its repair systems.
BiotechDeep TechHealthtechHouston, US
H. Davis Adkisson(Chief Scientific Officer)inChris Garabedian(Director)William Schwieterman(Board of Directors)Fred Callori(Director)
BoardAmanda De La Garza(Director)in
Co-investorsBios Partners
True Made Foods makes no-sugar condiments—including ketchup, BBQ sauces, and rubs—sweetened with fruits and vegetables such as butternut squash, carrots, and apples instead of refined or artificial sweeteners.
ConsumerDirect to ConsumerFoodTechAlexandria, US
Abraham Kamarck(Executive Officer, Director)in
BoardRichard Scheiner(Director)
Co-investorsBlack Jays VenturesCentral Texas Angel NetworkSiddhi Capital
SelfWrap develops bioabsorbable wrap materials for vascular grafts that conform to individual patient anatomy and are designed to be absorbed by the body, unlike alloy-based alternatives.
BiotechDigital HealthHealthtechMedical DevicesHouston, US
Tim Boire(Founder)inGeoffrey Lucks(Founder)in
BoardJoel Whitley(Director)inJim Monsor(Director)Robert Crutchfield(Director)in
Co-investorsAlumni VenturesC3 VenturesCreative VenturesGood Growth CapitalHealth WildcattersKube VC+10 more
Vessl designs adaptive prosthetic technology that adjusts to the body's dynamic changes to provide consistent comfort and natural movement for amputees.
Advanced ManufacturingHardwareHealthtechMedical DevicesWellness & FitnessIlderton, CA
Co-investorsRobin Hood VenturesTechstars
Zylö Therapeutics develops therapeutic delivery technology, focusing on product development in the biotech and drug-delivery space.
BiotechHealthtechGreenville, US
Scott R. Pancoast(CEO & Founder)inCharles E. Hinkle(Chief Financial Officer)inAndrew Draganski(Vice President, Product Development)Thomas Patrick Murray(Executive Officer)Lance Michael White(Director)Gary J Atkinson(Director)
Co-investorsAEON FoundryBoston Harbor AngelsHBS Angels of Boston
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
BimotalBMI Organ BankCAGE Bio Inc.CardioWiseDigital Seat MediaEnsemble OrthopedicsEoseraGale HSAGlidanceGreen Steel EnvironmentalHaxiotIn TUMO TherapeuticsKEYKlinriskMerge Labs, Inc.ModumetalMy Art CacheMyndVRNoninvasixNuvotheraPleiogenixRancho Santa Fe BioRevitalize Charging SolutionsRuby's Naturals, Inc.Smart Human DynamicsSmart Response TechnologiesSolGroStrategic Thermal LabsSurvey LocalTerecircuitsTradeverifydTympanogenZenblen
Exits · 1
1 IPOsSalarius PharmaceuticalsNASDAQ: DCOY
Portfolio news
latest coverage across their companiesCognition Therapeutics · manilatimes.net · Sep 8, 2026
True Made Foods · finance.yahoo.com · Oct 31, 2025
Frequently asked questions
- How many investments has Cowtown Angels made?
- Cowtown Angels has 61 tracked investments, 1 of which have exited, including 1 dated in the last 24 months.
- What stage does Cowtown Angels invest at?
- Cowtown Angels invests at the Pre-Seed, Seed, Series A stages.
- What sectors does Cowtown Angels focus on?
- Cowtown Angels focuses on Biotech, Cleantech, Consumer, Deep Tech, Healthtech, Medical Devices, New Materials, SaaS, Sector Agnostic.
- Where is Cowtown Angels located?
- Cowtown Angels is headquartered in Fort Worth, US.
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