National Institutes of Health (NIH) — 2017 Investments

Soligenix is a biopharmaceutical company developing treatments for rare diseases, with programs in photodynamic therapy for cutaneous T-cell lymphoma and psoriasis, immunomodulatory drugs for inflammatory conditions, and vaccine candidates for infectious diseases.

BiotechPrinceton, US

RCRichard C. Straube, MD MSc(Executive Officer)Karen Krumeich(Executive Officer)Oreola Donini, PhD(Executive Officer)CJChristopher J. Schaber(Executive Officer, Director)inAdam T. Rumage(Executive Officer)R. Christopher Cavalli, PhD(Executive Officer)

Co-investorsPOPontifax Venture Capital

3P Biotechnologies identifies plant-derived bioactive compounds and develops drug delivery systems targeting cancer and chronic disease prevention.

BiotechDeep TechHealthtechLouisville, US

Dr. Gupta(Founder)Al Poskanzer, PhD(Director of Strategic Partnerships)Niti Gupta, BA(Director of Finances & Administration)

AG Pharma is a theranostics company developing monoclonal antibodies against cancer-specific biomarkers, pairing targeted therapeutics with companion diagnostic tests for personalized cancer treatment.

BiotechHealthtechMedical Devices

Aavogen is a biotechnology company focused on muscle disease treatment through gene therapy.

BiotechDeep TechHealthtechMedical Devices

Buel Dan Rodgers(Founder & CEO)Chris Novashinski(Co-Founder & COO)Gary Carswell(Founder & President)

HealthtechSt. Paul, US

Angeline Conley(Executive Officer, Director)AFAaron Fletcher(Director)inDonald Santel(Director)Steve Seme(Executive Officer)

Co-investorsDEDEFTA PartnersIRIrishAngelsSOSoutheast Minnesota Capital Fund

AbleLink Smart Living Technologies develops research-based assistive and cognitive technologies, including GPS-guided travel apps, step-by-step daily living supports, simplified desktop software, and accessible cloud-based survey systems.

Digital HealthHealthtechImpact & Social Good

Dan Davies(Founder & President)

Accudava develops diagnostic kits that predict patient response to platinum-based chemotherapy, helping oncologists identify which patients will benefit from standard cancer treatment.

AI & Machine LearningBiotechDigital HealthHealthtechMedical Devices

Dr. Nahid Razi(CEO, Founder)

AcuraStem is a biotechnology company developing antisense oligonucleotide treatments for neurodegenerative diseases such as ALS and frontotemporal dementia, using its iNeuroRx technology platform for disease modeling and drug discovery.

AI & Machine LearningBiotechDeep TechHealthtechLongevityPasadena, US

JIJustin Ichida(Co-founder)inSASam Alworth(Founder)inMarcel van der Brug(Chief Scientific Officer)inRobert Bowser(Chief Scientific Officer)

BoardQing Liu-Michael(Director)Paul August(Director)

Co-investorsCACANTILEVER INVESTORSKEKeiretsu Forum

BiotechNew York, US

Christopher Frigon(Executive Officer)Jeffrey Gardner(Executive Officer)Tyler Martin(Executive Officer, Director)Phil Livingston(Director)

BoardMary Gin(Director)John Gallo(Director)

ATS Bio produces Saporin, a plant-derived enzyme used as a control reagent for targeted immunotoxins and ligand toxins in research applications.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesCalifornia, US

Douglas Lappi(Co-founder)Ronald Wiley(Co-founder)Denise Higgins

EleGARD is an FDA-cleared and CE-marked patient positioning device and cardiopulmonary board that elevates a patient's head and thorax during airway management and cardiopulmonary resuscitation procedures.

HardwareHealthtechMedical DevicesSycamore, US

Contract research organization specializing in CNS preclinical efficacy and neurotoxicity evaluations using its patented Enhanced Spine Profiling (ESP) technology.

Co-investorsTOTorrey Pines Investment

ALA Scientific develops BrainDancer, a dynamic phantom system that uses deep learning to identify and remove scanner-induced noise from fMRI signals, improving signal-to-noise ratios and enabling standardization across imaging sites.

AI & Machine LearningDeep TechHardwareHealthtechMedical Devices

AlphaThera develops oYo-Link reagents for rapid, site-specific, covalent labeling of antibodies with fluorescent proteins, oligonucleotides, and drug conjugates for life sciences researchers.

BiotechDeep TechPhiladelphia, US

Develops targeted MR imaging agents for early detection of Alzheimer's and other neurodegenerative diseases.

Co-investorsCECentral Texas Angel NetworkDODolby Family Ventures

Ambigroup provides waste management, demolition, and dismantling services with a focus on construction and demolition waste (RCD), operating recycling facilities that turn waste and materials into secondary raw materials.

Circular EconomyCleantechConstruction Tech

AmideBio discovers and designs peptide therapeutics for metabolic diseases, using in-silico design and its BioPure process to produce ultrapure peptides.

AI & Machine LearningBiotechDeep TechHealthtechBoulder, US

Michael H. B. Stowell(CSO, Founder and Board Member)Mikhail Plam(Executive Officer, Director)Pawel Fludzinski, PhD(CEO, President and Board Member)Pawel Fludzinski(CEO, President and Board Member)inDerek Watson(Fractional CFO)

BoardDavid Barker(Director)

Bend, US

Jean-Paul Audette(Executive Officer, Director, Promoter)Adam S. Carroll(Executive Officer, Director, Promoter)

BoardChristopher Kraybill(Director)J. Corey Schmid(Director)

Co-investorsGEGeekdom

Applied Separations manufactures sample preparation instruments and consumables based on supercritical fluid extraction and related chromatography technologies for analytical laboratories and industrial applications.

Advanced ManufacturingBiotechCleantechDeep TechHardwareNew MaterialsAllentown, US

Rolf Schlake(CEO)

Developer of advanced pulmonary drug delivery systems for systemic conditions and lung diseases

Co-investorsCACamden Partners

ZeroG 3D is a medical device that uses dynamic body-weight support technology to help patients safely rebuild strength and functional mobility during physical rehabilitation sessions.

HardwareHealthtechMedical DevicesRoboticsWashington, DC, US

Joe Hidler, PhD(Founder)

Avanti Biosciences is a biopharmaceutical company focused on therapeutic innovation and drug development across multiple therapeutic areas including oncology, cardiovascular disease, neurological disorders, and immunology.

BiotechDeep TechDigital HealthSan Diego, US

Gian Luca Araldi(Founder and Chief Executive Officer)

AyuVis develops novel small-molecule immunotherapies with a unique mode of action to fight inflammation and infection.

BiotechHealthtechMedical DevicesFort Worth, US

SASuchi Acharya(Founder and CEO)inDavid Riley(Chief Medical Officer)inDennis Dean(Head of CMC)Dale Christensen(Director of Early Development)Gagan Acharya(Executive Officer, Director)Stella M Robertson(Director)

Bacterioscan develops diagnostic technologies and solutions for bacterial detection and identification.

BiotechHealthtechMedical DevicesSt. Louis, US

Dana A. Marshall(President and Chief Executive Officer)inMEMichael E. Thaman, Sr.(CEO & Chairman of the Board)

BoardMichael E. Thaman(Director)Amnon Weischelbaum(Director)Richard R. Vietor(Director)James Brigham, Jr.(Director)

Provides technologies for detection, neutralization, and removal of endotoxin for bioresearch and bioprocess markets.

Co-investorsTATargeted Technology Funds

Benchlight Science is a publication that explains the vocabulary and concepts used in biotechnology and life-science research.

BiotechMedia & EntertainmentAlameda, US

Judith Segall(Director)Robert W Peabody(Executive Officer)Michael D West(Executive Officer, Director)William P. Tew(Executive Officer)

BoardNeal C Bradsher(Director)Alfred D Kingsley(Director)

BioVentures develops products and tools for genomics and molecular research, serving scientists and researchers exploring the genetic foundations of life.

BiotechE-commerce

BiVACOR is a clinical-stage medical device company developing a Total Artificial Heart (TAH), an electro-mechanical rotary blood pump with a single magnetically levitated rotor that replaces both ventricles for patients with end-stage biventricular heart failure.

HardwareHealthtechMedical DevicesHuntington Beach, US

DTDaniel Timms(Founder & Chief Technical Officer)inJames Dillon(Executive Officer, Director)Tom Vassiliades(Executive Officer, Director)WCWilliam Cohn(Chief Medical Officer)in

BoardBihua Chen(Director)PKPaul Kelly(Director)in

Co-investorsONOneVentures

BlueWillow Biologics develops an intranasal vaccine delivery platform using novel oil-in-water emulsion technology to address pandemic preparedness, infectious diseases, and food allergies.

BiotechHealthtechMedical DevicesAnn Arbor, US

CCChad Costley(President and Chief Executive Officer)inGAGeorge Arida(Chief Financial and Operating Officer)inJakub Simon(Chief Medical Officer)

Co-investorsMIMichigan Capital Network

CPG develops materials, instrumentation, and devices with patents spanning orthopaedic polymers, hydrogels, rheometry equipment, and medical sensors.

BiotechDeep TechMedical DevicesNew MaterialsCambridge, US

Dr. Gavin Braithwaite(Chief Executive Officer)Dr. Stephen Spiegelberg(Chief Scientific Officer)

Cambridge Medical Technologies designs and manufactures medical devices for non-invasive blood biomarker monitoring.

HardwareHealthtechMedical DevicesCambridge, GB

Michael Lacey-Solymar(Chairman)Jack Jachmann(Chief Executive Officer)James Cooke(Chief Financial Officer)John Currie(Chief Scientist)

Co-investors2424 Haymarket

Camellix develops natural health care products supported by laboratory research and clinical trials.

BiotechHealthtechWellness & FitnessAugusta, US

Dr. Stephen Hsu(Founder and CEO)

CapsicoHealth develops AI and large language model technology platforms that help life sciences companies and healthcare providers optimize revenue, margins, and personalized care delivery using population risk analysis and clinical decision tools.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechSilicon Valley, US

RameshLaurentWilliam Stein, III(Chief Medical Officer)

Developing implantable low-energy pain-free atrial cardioverters for atrial fibrillation.

HealthtechSt. Louis, US

M. Brent Shelton(Executive Officer)Paula Skjefte(Executive Officer, Director)Nick Lanners(Executive Officer)Igor Efimov(Director)

BoardEric A. Gulve(Executive Officer, Director)Warren Watson(Director)

Co-investorsBRBroadview VenturesRIRiverVest Venture PartnersCUCultivation Capital

A biotech company developing a caveolae-based drug delivery platform that uses engineered molecular carriers to transport therapeutic agents across biological barriers into diseased tissues.

BiotechMedical DevicesLa Jolla, US

Jan E. Schnitzer(Founder)

Cayman Chemical supplies assay kits, antibodies, biochemicals, and proteins, and provides contract research services for the life sciences research market.

Biotech

Cell-Safe develops an implantable immunoisolation device that houses bioengineered islet cell constructs perfused with ultrafiltrate for β-cell replacement therapy in diabetes, with potential applications for other diseases such as liver failure and ALS.

BiotechDigital HealthMedical Devices

CellSight Technology develops molecular imaging technologies for precision health and cancer detection.

AI & Machine LearningBiotechDeep TechDigital HealthMedical Devices

Sanjiv Gambhir(Founder)Sam Quezada(Co-founder)Shahriar Yaghoubi(Co-founder)Aruna Bodapati Gambhir(CEO)

Cerrx publishes online articles about menstrual and women's health topics, such as causes of blood clots during periods.

BiotechFemTechMedia & EntertainmentLubbock, US

CPC. Patrick Reynolds, M.D., Ph.D.(Director)Richard Love(President & CEO)

BoardBarry Maurer, M.D., Ph.D.(Director)

BiotechDallas, US

Perry Molinoff(Director)John D. Harkey, Jr.(Director)Brent Duncan(Director)Pat Confalone(Director)Dennis Robbins(Director)David Hitt II(Director)

Cetya Therapeutics develops histone deacetylase inhibitors (HDACi) based on analogs of largazole, with a lead candidate, CT-101, being developed to treat sickle cell disease.

BiotechHealthtechFort Collins, US

Champaign Imaging develops advanced technology for neuroimaging using magnetic resonance imaging (MRI) techniques.

Deep TechHardwareHealthtechMedical DevicesChampaign, US

Curtis A. Corum(Co-Founder & CEO)Stephen Otto(VP, Business Development)

Click Diagnostics offers the Visby device, an at-home PCR test that delivers results in about 30 minutes for common curable STIs including chlamydia, gonorrhea, and trichomoniasis.

BiotechConsumerDigital HealthMedical DevicesMenlo Park, US

ADAM DE LA ZERDA(Director, Promoter)

BoardAJIT SINGH(Executive Officer, Director)JEROME BEHAR(Director)STEVEN ROSSTON(Director)

Co-investorsJAJam Fund

CoapTech makes the PUMA-G System, an FDA-cleared ultrasound-based device for bedside feeding tube (gastrostomy) placement, used in ICUs, step-down units, IR suites, and long-term acute care hospitals.

BiotechHardwareHealthtechMedical DevicesBaltimore, US

STSteven Tropello(Executive Officer, Director)inHCHoward Carolan(Executive Officer, Director)in

BoardJOJohn Osborne(Director)inPeter Boyd(Director)William Walker(Director)Tim Collins(Director)

Co-investorsGOGood Growth CapitalUNUniversity System of Maryland Momentum FundHUHunniwell Lake Ventures LLC

Cognivive develops at-home virtual reality therapeutics that adapt in real time to patient performance, designed for patients to self-administer.

Digital HealthHealthtechMedical Devices

Co-investorsCRCreative Destruction Lab (CDL)

An independent research and consulting organization funded by the National Institutes of Health that develops innovative approaches to public health through research and collaboration with academic and private sector experts.

Digital HealthHealthtechWellness & FitnessEugene, US

William Collinge(President)

Community Science is a social enterprise founded in 1997 that provides consulting and evaluation services to support social change and equity work.

Enterprise SoftwareImpact & Social GoodWashington, US

CorMedix develops and commercializes therapeutic products for life-threatening diseases and conditions, including DefenCath (taurolidine and heparin).

BiotechHealthtech

Co-investorsHAHarbor Light Capital Partners

Cellular Scientist develops automated laboratory devices and specialized cell culture media for drug discovery and preclinical research.

BiotechDeep TechEnterprise SoftwareHealthtechMedical DevicesResearch Triangle Park, US

Creatv is a company with three divisions: a microfabrication and electroplating services unit, a cancer diagnostics research division (Creatv Bio) that uses CellSieve microfilters to isolate and image cancer-associated cells from blood, and LifeTracDx, which offers diagnostic blood testing through a CLIA-certified laboratory.

BiotechHardwareMedical Devices

Curii is a software company that develops and supports Arvados, an open-source platform for storing, organizing, processing, and sharing large genomic and biomedical datasets and running reproducible workflows at scale.

AI & Machine LearningBiotechData & Infrastructure

George Church(Founder)Sarah Wait Zaranek(CEO & Founder)Sasha Wait Zaranek(Chief Innovation Officer & Founder)Tom Clegg(Chief Architect & Founder)Ward Vandewege(Founder)Peter Amstutz(CTO & Founder)

Curtana Pharmaceuticals develops small molecule drugs targeting cancer stem cells in brain tumors, specifically gliomas and related CNS malignancies.

BiotechDigital HealthMedical DevicesAustin, US

GSGregory Stein(Chief Executive Officer, Co-Founder, Chairman)

Co-investorsTHThynk Capital

CytoBioscience develops automated patch clamp instruments (CytoPatch) and offers contract research organization (CRO) services, cell lines, and consumables for electrophysiology and ion channel research.

BiotechHardwareHealthtech

Co-investorsTATargeted Technology Funds

Co-investorsLOLongitude Capital

Direct Electron manufactures direct detector cameras for electron microscopy applications, including single-particle cryo-EM, in situ transmission electron microscopy (TEM), and low-energy electron microscopy.

BiotechDeep TechHardwareMedical DevicesSemiconductors

Co-investorsSOSocial Starts

Dynaflow develops computational fluid dynamics software and specialized hardware systems for hydrodynamic analysis, cavitation testing, and water-based material erosion applications.

Cloud ComputingDeep TechDefense TechDeveloper ToolsHardwareNew MaterialsSaaSAnnapolis Junction, US

Dr. Georges L. Chahine

DynamiCare offers a digital recovery platform that uses behavioral science and technology to help individuals reduce or eliminate their use of alcohol, drugs, and tobacco.

Digital HealthHealthtechMental HealthNewton, US

EGEric Gastfriend(Executive Officer, Director)inKelley Bowker(Was no longer CEO at time of closing.)inDavid Gastfriend(Director)

BoardBenjamin Blum(Left board upon closing.)in

Co-investorsEAEarly Light VenturesMEMEDA AngelsMEMEDA VenturesTHThe MBA FundHYHyperplane Venture Capital

Eclipsebio provides RNA biology analytical services and sequencing-based assays that help drug developers and researchers characterize RNA at nucleotide-level resolution and generate datasets for AI-driven drug discovery.

AI & Machine LearningBiotechDeep TechSan Diego, US

EYEugene Yeo(Director)PCPeter Chu(Executive Officer, Director)inEric L Van Nostrand(Director)Hallie Kuhn(Director)

BoardEWEdmond Wong(Director)inDaniel Vasella(Director)

Co-investorsBRBrainstorm VenturesIGiGlobe PartnersMAMagnetic VenturesPHPhoenix Venture Partners

Edovo provides educational and rehabilitative programming delivered on tablets inside correctional facilities, covering literacy, GED and college courses, vocational training, and substance abuse and mental health curricula.

EdTechGovTechImpact & Social GoodChicago, US

BHBrian Hill(Founder)inCACarl Alguire(Executive Officer, Director)in

BoardHarry Harczak(Director)Greg Lernihan(Director)Chris Bentley(Director)

Co-investorsSUSustainVCTRTribal VenturesIMImpact EngineKAKapor CapitalTWTwilio Ventures

BiotechMaple Grove, US

Jafar Golzarian(Executive Officer, Director, Promoter)Jon Freeman(Executive Officer)Lihui Weng(Executive Officer)Omid Souresrafil(Executive Officer, Director, Promoter)

BoardGerald D. Van Eeckhout(Director)Reza Malek(Director)

EncepHeal develops small-molecule medications targeting the dopamine transporter to treat stimulant addiction, including cocaine and methamphetamine, for which no FDA-approved treatments currently exist.

BiotechHealthtechWinston-Salem, US

ALAaron Lazarus(Founder)inOROmeed Rahimi(Founder)in

Co-investorsY Y Combinator

EnLiSense develops wearable sensor technology for real-time, non-invasive biomarker monitoring across wellness and medical applications.

Digital HealthMedical Devices

Shalini Prasad(Co-founder)

EnviroMetrix Instruments (EMI) designs and manufactures real-time laser light-scattering instruments that measure the size and concentration of particulates in process industries and consumer products.

Advanced ManufacturingDeep TechHardware

Donald Holve(Co-founder & Owner)Janice Holve(Co-founder & Owner)

Everglades Biopharma develops ligand-based therapeutic antibodies for vascular diseases, using proprietary ligandomics technology to identify disease-specific targets with higher efficacy and fewer side effects.

BiotechHealthtechMedical DevicesHouston, US

FaceView Mask makes a surgical face mask with a clear window designed to allow patients to see the clinician's face and support communication in healthcare settings.

Direct to ConsumerHealthtechMedical DevicesSan Francisco, US

Jeanne Hahne(Founder)

Ferrologix is a biotechnology startup developing bioprocessing tools that use arrays of cell-sized micromagnets, made with semiconductor manufacturing techniques, to sort and analyze biological cells.

BiotechDeep TechMedical Devices

FLAG Therapeutics develops drug delivery and dosage form solutions for pharmaceutical development and manufacturing, serving biotech and pharmaceutical companies in oncology and rare disease therapeutics.

BiotechHealthtechMedical DevicesRaleigh, US

RUHI AHMED(Executive Officer)FLFrank L. Sorgi(President and Chief Executive Officer)in

Floreo develops virtual reality experiences for education and therapeutic purposes, with a focus on individuals with intellectual and developmental disabilities.

AI & Machine LearningDigital HealthEdTechHardwareHealthtechWashington, US

VRVijay Ravindran(Founder)in

Co-investorsAIAIFBLBloomberg BetaCICity LightCOColopl NextLILifeforce CapitalMOMount Pleasant Ventures+2 more

Focal Medical develops energy-based drug delivery systems that use a targeted electric field to move drug molecules precisely into target cells via non-blood pathways, aiming to reduce systemic side effects.

BiotechHealthtechMedical DevicesRaleigh, US

Fox Learning Systems produces documentary-style video training courses and educational media for professional development and workplace training.

EdTechEnterprise SoftwareHealthtechMedia & Entertainment

From the Future builds VR and AI-based training and education solutions for skilled trades and enterprise workforces, using its DRIVE platform, Hololab VR client, and HoloGPT AI framework.

AI & Machine LearningEdTechGaming

Mike Christian(CEO and Founder)

Fzata develops biotherapeutics for C. difficile infection and inflammatory bowel disease, leveraging proprietary antibody and vaccine technologies.

BiotechHealthtechMedical DevicesHalethorpe, US

Zhiyong Yang(Co-founder and CEO)Hanping Feng(Co-Founder & Chief Scientific Officer)

Galera Therapeutics is a biotechnology company developing antibody-based and other therapeutics.

BiotechHealthtechMedical DevicesMalvern, US

MSMel Sorensen(Executive Officer, Director)inJSJoel Sussman(Executive Officer)inJeffery L. Keene(Executive Officer)inDPDennis P. Riley(Executive Officer)inJon T. Holmlund(Executive Officer)RARobert A. Beardsley(Executive Officer, Director)in

Co-investorsNENew Enterprise Associates (NEA)SOSofinnova Ventures

GenetiVision produces transgenic Drosophila flies for research laboratories using site-specific integration and other genetic engineering techniques.

BiotechDeep TechHouston, US

Graeme Mardon(Founder)Rui Chen(Founder)

GenNext Technologies develops tools and platforms for life science research, specifically focused on radical protein footprinting (HRPF) technologies for biopharmaceutical discovery and development.

AI & Machine LearningBiotechDeep TechHardware

Josh Sharp(CTO)Scot R Weinberger(President and CEO)

GenTegra develops sample collection and storage technology that stabilizes biological samples including tissue, DNA, and blood for clinical, research, and forensic applications.

BiotechHealthtechMedical DevicesNew Materials

William Anderson(Co-founder)Mike Hogan(Co-founder)James Nelson(Co-founder)

Gentuity develops high-frequency optical coherence tomography (HF-OCT) imaging systems for interventional cardiologists to visualize and treat coronary artery disease.

AI & Machine LearningHardwareHealthtechMedical Devices

DavidDesmondRennyJasonAlexRaj

Integrated platforms for rapid delivery of low-cost, high-resolution genomic maps for research and diagnostics.

Co-investors1111.2 Capital

Co-investorsCACanaan Partners

GlycoT Therapeutics develops chemoenzymatic protein glycosylation technologies for the synthesis of homogeneous antibody glycoforms and site-specific antibody-drug conjugates for therapeutic applications.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Dr. Lai-Xi Wang(Founder and President)

GoDx builds GoDEVICE, a portable, automated point-of-care molecular diagnostics platform that runs single-use cartridges to perform sample preparation, targeted pathogen and antimicrobial-resistance detection, NGS library preparation, and environmental surveillance.

BiotechHealthtechMedical DevicesMadison, US

Real-time objective behavioral health monitoring

HealthtechLong Island City, US

MMMark Mathews(Director)Paul Gilbert(Executive Officer, Director)

Co-investorsCUCU Healthcare Innovation FundINInformed Ventures Advisors, LlcWAWaterline VenturesCICity LightINInflect Health

HeartLander is a robotic walker surgical device in pre-clinical development that attaches to the epicardium through a small percutaneous port and moves across a beating heart to enable minimally invasive procedures such as cardiac ablation, myocardial regeneration therapy delivery, and biventricular pacing lead placement.

HealthtechMedical DevicesRobotics

Hemex Health develops and commercializes the Gazelle diagnostic platform, including point-of-care readers and tests for conditions such as sickle cell disease and hemoglobin variants.

Digital HealthHealthtechMedical DevicesPortland, US

PWPatricia White Seminario(Executive Officer, Director, Promoter)PGPeter Galen(Chief Innovation Officer, Co-Founder)inPWPatti White(Chief Executive Officer, Co-Founder)inDaren Bledsoe(Sr. VP, Engineering & Operations)inGVGerrit van Roekel(VP, Business Development)inUGUmut Gurkan(Chief Scientist, Microfluidics)in

Co-investorsCWCWRU Technology VenturesELElevate CapitalIDIdeashipIMImpact India Investment PartnersPOPortland Seed Fund

HepaTx develops stem cell-based hepatocyte therapies for liver disease treatment as an alternative to organ transplantation.

BiotechHealthtechMedical DevicesSan Francisco, US

ESEric Schuur(CEO)inMark Chao

Co-investorsISiSelect FundSASand Hill AngelsSTStartXY Y CombinatorPAPalapa VenturesSPSP Investment Fund

Hesperos develops "Human-on-a-Chip" organ-on-a-chip platforms, offering custom multi-organ models (up to 5 organ or tissue types) with functional readouts such as gene expression and electrophysiology.

BiotechDeep TechMedical DevicesOrlando, US

MLMichael L. Shuler(Co-founder)inJJJames J. Hickman(Chief Scientist)inLFLawrence Florin(Chief Executive Officer)inJSJames Stanker(CFO)

Co-investorsBTBtomorrow Ventures

Hinge Bio is a biotechnology company developing next-generation therapeutics based on its GEM-DIMER platform, aimed at improving efficacy and reducing resistance and side effects.

BiotechHealthtechBurlingame, US

Daniel J. Capon(Director)CMCarin Mueller Rollins(Co-Founder & Chief Operating Officer)HEHarold E. Selick, PhD(Executive Officer, Director)Miriam Siekevitz(Executive Officer)inHarold E. "Barry" Selick(Chief Executive Officer & Director)PBPaul Brunetta(Chief Medical Officer)in

Co-investorsPOPoint72AGAgent CapitalBABaruch Future VenturesINInVivium CapitalRIRidgeback Capital

BiotechCalabasas, US

Danny JJ Wang(Executive Officer, Director)Conn Davis(Director)Marc Korczykowski(Executive Officer, Director)

HylaPharm is a University of Kansas spinout developing cancer therapies that reverse tumor-induced immune suppression to make "cold" tumors responsive to the immune system, with the goal of improving response to checkpoint inhibitors in human patients.

BiotechDeep TechHealthtechLawrence, US

iFyber is a product development and research services firm that helps companies commercialize technologies at the intersection of chemistry, biology, and materials science.

BiotechDeep TechHealthtechMedical DevicesNew MaterialsIthaca, US

Aaron Strickland(Co-founder & Vice President of Research and Development)

Inanovate is a diagnostics company that developed Lyme-ID, an FDA 510(k)-cleared blood test for Lyme disease based on its proprietary Bio-ID technology.

BiotechSioux Falls, US

David Ure(Executive Officer, Director)inJames E Oury(Executive Officer)

BoardBlaine Crissman(Director)Katie Pohlson(Director)Peter D. Los(Director)David Arslanian(Director)

Incom manufactures glass and polymer microstructures used in optical and display applications for medical, dental, scientific, and defense industries.

Deep TechDefense TechHardwareMedical DevicesNew MaterialsCharlton, US

Inhibrx develops protein therapeutics, using target biology and protein engineering to create therapeutic candidates in clinical trials for conditions including sarcoma and head and neck cancer.

BiotechLa Jolla, US

MLMark Lappe(Executive Officer, Director)inBrendan Eckelman(Director)inDoug Forsyth(Director)Jon Faiz Kayyem(Director)Margery Fischbein(Director)

BoardJudith Li(Director)

Co-investorsLALAVLILilly Asia VenturesRARA CapitalVIViking GlobalOXOxford Finance LLC

Innovative Biochips develops microfluidic technologies for biomedical research and diagnostics applications.

BiotechDeep TechHardwareLongevityMedical DevicesHouston, US

InRedox develops and commercializes self-organized nanoceramic materials, including nanoporous anodic aluminum oxide, for advanced technology and research applications.

Deep TechHardwareNew MaterialsNorthern Front Range of Colorado, US

Dmitri Routkevitch(Co-Founder, President & CTO)F. Howland "Howie" Carpenter(Co-Founder, VP Business Development)Michael H. B. Stowell(Co-Founder, Chair of Scientific Advisory Board)

Baltimore, US

ASAlexander Sulakvelidze(Executive Officer, Director)inJohn J Woloszyn(Executive Officer, Director)inMRMel Ruzicka(Executive Officer)

BoardGary Pasterneck(Director)Patrick Hervy(Director)

IonOptix manufactures systems for fluorescent ion quantitation and muscle mechanics measurements used in preclinical cardiac and cellular research.

BiotechDeep TechHardwareHealthtechMedical DevicesWestwood, US

Douglas Tillotson(Founder)

iotaMotion develops robotic systems for cochlear implant surgery, assisting otolaryngologists in achieving precision beyond human capability.

HealthtechMedical DevicesRoboticsSt. Paul, US

Marlan Hansen, MD(Executive Officer, Director)MHMarlan Hansen(Executive Officer, Director)Christopher Kaufmann(Executive Officer, Director)MHMarlan Hansen, MD, FACS(Co-founder & Chief Medical Officer)Michael Lobinsky(Executive Officer, Director)

BoardWWWayne Wallace(Director)

Co-investorsISISA VenturesMUMutual Capital PartnersNENext Level Ventures

JANUS Research is a defense-focused organization providing research, analysis, and solutions for government customers.

AI & Machine LearningDeep TechDefense TechSector AgnosticSpace Tech

John Dewey(Chief Executive Officer)Curtis Sumner(Chief Operating Officer)

Co-investorsGEGemini Ventures

Kephera develops diagnostic technologies and products targeting point-of-care testing, third-party assay development, and specific disease markets including Lyme disease and neuroinfectious diseases.

BiotechDigital HealthHealthtechMedical DevicesFramingham, US

Andrew Levin, Ph.D.(Chief Executive Officer / Chief Scientific Officer)

Kinetic River provides nanoparticle analysis services, characterizing exosomes and other nanoparticles in customer-submitted samples and delivering detailed reports.

BiotechDeep TechHealthtech

Dr. Vacca(Founder)

BioKinetiq develops next-generation replacement enzymes aimed at reducing the treatment burden for people with rare diseases.

BiotechHealthtech

Digital HealthMedical Devices

Co-investorsBOBoulder VenturesENEntrada Ventures

Lucendi develops AI-enabled smart measurement platforms using computational microscopy and holographic imaging for micro-object detection and characterization across various industrial and scientific applications.

AI & Machine LearningDeep TechHardwareLos Angeles, US

Maxim Batalin(Executive Officer, Director)Aydogan Ozcan(Director)

BoardGilbert Hakim(Director)

Luxel manufactures photocathodes for high-performance streak cameras used in scientific instrumentation, including ultra-flat cathodes optimized for precise time resolution.

Advanced ManufacturingDeep TechHardwareNew MaterialsFriday Harbor, US

MAA Laboratories is a specialty pharmaceutical company developing nanoparticle-based drug products using its proprietary NanoCont™ continuous manufacturing platform to address unmet medical needs across multiple therapeutic areas.

BiotechDeep TechHealthtechMedical DevicesResearch Triangle Park, US

Dr. Anjani Jha(Founder and CEO)

Manzanita Pharmaceuticals develops novel therapeutics targeting pain management and cancer treatment through targeted drug delivery technologies.

BiotechHealthtechMedical Devices

Robert R. Webb(Co-founder, Investor and Board Member)Constance McKee(President & CEO)Stephen B. Kahl(Chief Scientific Officer, Vice President & Principal Scientist)

Martineau & Associates designs computer vision instruments and imaging systems to monitor complex animal behavior, primarily using zebrafish as a research model.

AI & Machine LearningBiotechDeep TechHardwareHealthtechMedical DevicesMenlo Park, US

Pierre Martineau

BiotechSan Francisco, US

MMMartin Moore(Executive Officer, Director, Promoter)RTRoderick Tang(Executive Officer, Director, Promoter)in

Co-investorsFUFundRx

HealthtechBothell, US

Jon Hauser(Executive Officer, Director)Corey Fagan(Executive Officer, Director)Todd Lowdon(Executive Officer, Director)Nicholas Talbott(Executive Officer)Eric Meier(Executive Officer, Director)

Co-investorsENEntrepreneurs'

Metaclipse Therapeutics develops next-generation immunotherapies and vaccines for cancer and infectious diseases using proprietary biological adjuvants.

AI & Machine LearningBiotechDeep TechHealthtech

Micro-Leads develops implantable neurostimulation devices and a closed-loop platform for spinal cord stimulation, peripheral nerve stimulation, and brain-computer interfaces.

Deep TechHardwareMedical Devices

Microgen develops and manufactures rapid point-of-care diagnostic tests for infectious diseases, targeting public health and clinical applications with solutions designed for speed, cost-effectiveness, and ease of use.

BiotechDeep TechHealthtechMedical Devices

MicroMGx runs a high-throughput natural product discovery process that combines metabolomics and genomics (metabologenomics) to find bioactive compounds produced by microbes, supplying patented natural products to life science R&D organizations.

AgTechAI & Machine LearningBiotechDeep TechEvanston, US

RTRegan Thomson(Co-founder & Board Member)inWMWilliam Metcalf(Chairman of the Board and CoFounder)JKJack Kloeber(CEO and Co-Founder)inNLNeil L. Kelleher(Co-founder)JKJennifer Kelleher(COO and Corporate Secretary)

BoardAnthony Goering(Director)

Co-investorsAGAg Ventures AllianceAGAgLaunch AcceleratorTHThe Innovation Space

ION manufactures wearable devices for continuous health and behavioral monitoring, including alcohol consumption tracking capabilities for individuals and monitoring partners.

HardwareHealthtechIoTWellness & FitnessSanta Barbara, US

Evan R. Strenk(Executive Officer, Director)Bob Lansdorp(Director)

MiraVista Diagnostics is a CAP and CLIA certified clinical reference laboratory specializing in diagnostic testing for serious fungal infections, processing over 100,000 fungal diagnostic tests annually.

BiotechHealthtechMedical Devices

Lawrence Joseph Wheat(Founder)

miRecule is a biotechnology company developing therapeutics, with programs focused on oncology.

BiotechHealthtechGaithersburg, US

ADAnthony D. Saleh(CEO)inDLDave Lemus(COO/CFO)in

Co-investorsALAlumni VenturesBOBoutique Venture PartnersBRBrown and White VenturesPAPathway BioventuresTATachyon VenturesUNUniversity System of Maryland Momentum Fund+1 more

Mirimus is a preclinical contract research organization (CRO) and biotech that uses gene editing and RNA interference (RNAi) technologies to build genetically engineered animal and cellular disease models.

BiotechDeep TechHealthtech

Darien, US

Ki Chon(Executive Officer, Director)Justin Chickles(Executive Officer, Director, Promoter)

BoardPatrick O'Neill(Director)

Monon Bioventures assists early-stage academic and clinical investigators in translating their research into commercially viable assets attractive to follow-on funders.

BiotechHealthtech

Morgan & Mendel develops genetic testing and analysis technologies for medical diagnostics, focusing on identifying genetic risk factors and functional analysis of genetic variation.

BiotechDigital HealthHealthtechMedical DevicesNew York, US

Andrew Paul(CEO)Thomas Kusch(PhD)Harry Ostrer(Professor of Pathology and Pediatrics, Director of Genetic and Genomic Testing)Johnny Loke

BiotechCambridge, US

George Whitesides(Director)Peter Howe(Executive Officer)Brian Mayers(Executive Officer)in

BoardHerbert Winokur(Director)Myer Berlow(Director)

NanoAffix develops a portable analyzer for real-time, onsite detection of toxic contaminants in drinking water, with current focus on lead detection at point-of-use.

CleantechDeep TechHardwareHealthtechIoT

Nanocomposix manufactures hydroxyapatite nanoparticles—biocompatible calcium phosphate materials—for research and medical applications including bone regeneration, drug delivery, dental care, and water purification.

Advanced ManufacturingBiotechDeep TechNew MaterialsSan Diego, US

Steven Oldenburg(Founder)

Nanohmics performs collaborative and client-funded research and advanced product development in applied materials science and instrumentation, building novel sensing devices and measurement platforms for applications such as surveillance, detection, and energy conversion.

CleantechDeep TechDefense TechEnterprise SoftwareHardwareNew MaterialsSemiconductors

Neofluidics develops laboratory automation and analytical instruments for research labs, focused on tools that prepare, process, and characterize samples.

AI & Machine LearningBiotechHardware

NeuraLynx builds neural recording data acquisition and analysis systems, including its Digital Lynx multichannel recording and stimulation platform, telemetry systems, and portable acquisition tools.

Deep TechHardwareHealthtech

NeuroLux develops ultra-miniaturized, flexible optoelectronic devices for implantation into brain regions, enabling wireless power delivery and control for optogenetic research and drug delivery applications.

BiotechDeep TechHardwareMedical DevicesEvanston, US

John A. Rogers(Co-Founder)Anthony R. Banks(CEO and Co-Founder)Robert W. Gereau(Co-Founder)Michael R. Bruchas(Co-Founder)

NovaFlux develops medical devices using proprietary two-phase flow technology to sterilize medical channels, remove biofilm, and enable drug delivery, with applications in hemodialysis, infection control, and otitis media treatment.

Deep TechHealthtechMedical DevicesNew Jersey, US

Mohamed E. Labib(Chief Executive & Chief Scientific Officer)

BiotechSan Bruno, US

Guido Lanza(Executive Officer, Director)JGJohn Griffin(Executive Officer)

BoardBruce Booth(Director)Steve Hall(Director)Lucio Lanza(Director)

Oligomerix is a biopharmaceutical company developing therapeutic compounds, with leadership focused on advancing drug candidates through clinical development stages.

BiotechDeep TechHealthtechLongevityMedical DevicesWhite Plains, US

Eliot Davidowitz(Executive Officer, Director)James Moe(CEO, Head Discovery & Strategy, Co-founder, Director)inEJEliot J. Davidowitz(Chief Scientific Officer, Co-Founder)Dr. Moe(Founder)Dr. Davidowitz(Founder)William Erhardt(Executive Officer, Director)

Co-investorsCOCounterview Capital

Organovo develops regenerative medicine therapies using bioprinting technology to treat serious liver diseases.

BiotechDeep TechHealthtechMedical Devices

Keith Murphy(Executive Chairman)

Co-investorsAUAurum Venture PartnersKHKhosla Ventures

Orthocare Innovations designs and manufactures prosthetic and orthotic devices that automatically adapt to users' movements and integrate mobile technology to deliver real-time activity data to clinicians.

HealthtechMedical DevicesRoboticsSaaS

David Boone

Ossium Health develops cellular therapies and bioengineered products for clinical use, leveraging adult stem cell technologies and advanced cell processing platforms.

BiotechHealthtechMedical DevicesSan Francisco, US

KCKevin Caldwell(Founder)inDr. Woods(Chief Science Officer, Co-Founder, EVP, CLIA Laboratory Director)SGSebastian Giwa(Director)inEWErik Woods(Founder)in

BoardWTWilliam Trenchard(Director)inThomas Cycyota(Director)

Co-investorsALAlumni VenturesFEFemHealth VenturesFIFirst Round CapitalGAGaingelsGEGeneral CatalystHEHemisphere Ventures LLC+6 more

Oxford Biomedical Research develops research products including assays, antibodies, and enzymes for drug metabolism and biochemical applications.

BiotechDeep TechDigital HealthHealthtechMedical DevicesRochester Hills, US

Denis M. Callewaert(Founder)

BiotechBaltimore, US

Weijie Poh(Manager)Joshua Weiyuan Wang(Manager)

PECA Labs develops cardiovascular implants—including vascular grafts and the MASA Valve, a polymeric bi-leaflet valved conduit for pulmonary valve reconstruction—based on a proprietary tunable polymeric material platform.

BiotechHealthtechMedical DevicesNew MaterialsPittsburgh, US

C. Douglas Bernstein(CEO)DBDoug Bernstein(CEO, Co-Founder)inDADr. Arush Kalra(CSO, Co-Founder)Jamie Quinterno(COO, Co-Founder)inDavid Smith(Executive Officer)Bob Donohue(Director)

A spine surgery clinic in Fairfax, Virginia that provides orthopedic spine care and back pain treatment with integrated digital health tools and personalized patient engagement.

Digital HealthHealthtechMedical DevicesFairfax, US

Atiyya H. Mughal(MD, MS)Sohail K. Mirza(MD, MPH)

Pharmazz is a biopharmaceutical company developing and commercializing therapeutics for critical care and acute medicine, focused on Endothelin-B receptor agonists and resuscitative agents for conditions such as hypovolemic shock, ischemic stroke, and septic shock.

BiotechHealthtechWillowbrook, US

AGAnil Gulati(Founder & CEO)inDCDavid Costello(Executive Officer)SGSunil Gulati(Executive Officer)inDaniel Stauder(Executive Officer)Gaylord Toft(Executive Vice President)Ajit Srimal(Director)

PhenoVista provides contract research services focused on phenotypic and high-content imaging studies, using quantitative fluorescence microscopy and cell-based disease models to support R&D and drug discovery decisions.

BiotechDeep TechHealthtechSan Diego, US

James G. Evans, Ph.D.(CEO)inAEAnthony Essex, Ph.D.(CSO)inBrian Conn(Executive Officer)James G. Evans(CEO)Anthony Essex(Executive Officer, Director)

PhotoSound Technologies develops and sells biomedical imaging systems based on optics and photoacoustics, including 3D preclinical imaging instruments and OEM electronics for multi-channel data acquisition.

BiotechHardwareHealthtechMedical DevicesHouston, US

Physcient develops Differential Dissection, a powered blunt surgical dissector that separates soft tissues connecting other tissues without cutting or burning, leaving blood vessels, organ capsules, and nerve sheaths intact.

HardwareHealthtechMedical DevicesDurham, US

CHARLES A. PELL(Executive Officer, Director)HCHugh Crenshaw(Founder)inETERIC T. ESPENHAHN(Executive Officer)

BoardCHRIS DUNN(Director)KEVIN SCHIMELFENIG(Director)R. FREDERICK MCCOY, JR.(Director)

Co-investorsELElevate Innovation PartnersLALaunchCapitalNCNC IDEA

PinMed develops customized hardware, software, and analytical services for medical researchers and clinical centers, specializing in continuous patient monitoring systems compatible with MRI and other imaging environments.

AI & Machine LearningDigital HealthHardwareHealthtechMedical Devices

Polarean is a medical imaging company that manufactures xenon-based imaging products for healthcare applications and maintains compliance with pharmaceutical industry standards and regulations.

Deep TechHardwareHealthtechMedical DevicesDurham, US

Bastiaan Driehuys(Founder and Chief Scientific Officer)KWKENNETH WEST(Executive Officer)JAYE MCDERMOTT(Executive Officer)Kiarash Emami(Co-founding member, Vice President, Technology and Applications)

BoardDan Deaton(Director)John Sudol(Director)

Co-investorsSESeneca Partners

Possibilities for Change offers evidence-based youth mental health screening tools that let schools and health programs mix and tailor assessments such as RAAPS, PHQ-9, and GAD-7 to identify risk and guide intervention.

Digital HealthEdTechMental Health

Potrero Hill Therapeutics discovers and develops new drug candidates and therapeutic programs.

BiotechSan Francisco, US

Jeremy Blitzer(Co-founder and Managing Director)Steve Halasz(Co-founder and Managing Director)

Praevium Research designs and manufactures miniaturized semiconductor lasers, detectors, and photonic integrated circuits for applications in medicine, agriculture, and communications.

Deep TechHardwareSemiconductors

PPS develops capacitive tactile sensing technology and software for measuring pressure and contact in applications including medical devices, robotics, ergonomics, and automotive systems.

Data & InfrastructureDeep TechDeveloper ToolsHardwareIoTMedical Devices

BiotechBoise, US

Michael O'Donnell(Executive Officer)Emily Stein(Executive Officer, Director)

BoardTerry Fadem(Appointment effective upon this financing.)David Eigen(Appointment effective upon this financing.)

Prolynx develops ultra-long-acting therapeutics for obesity and metabolic diseases such as type 2 diabetes, using a hydrogel-based microsphere platform with tunable release linker chemistry to control drug release over extended dosing intervals.

BiotechDeep Tech

GAGary Ashley(Co-Founder)inDSDaniel Santi(Co-Founder)inCBChris Boulton(CEO)inSimon Harnest(Chief Financial Officer)inAMAmer Mirza(Chief Scientific Officer)inCWChristian Weyer(Chief Medical Officer)in

Co-investorsMOMonograph Capital PartnersOROrbiMed