Palo Alto · Pre-Seed–Seed · 42 people tracked
Also known as GENERAL INCEPTION MANAGEMENT, LLC
Investment thesis
General Inception acts as a business co-founder for scientific and technical entrepreneurs building science-based companies. Its model centers on assembling the right people, customers, and funding partners at the optimal time for company formation and growth. GI supports founders across legal, financial, business strategy, and operational challenges, partnering through company formation, product development, and institutional fundraising. Its portfolio forms an interconnected ecosystem that shares access to new technologies, customers, and markets. The firm focuses on translating deep tech visions into customer-facing businesses, guiding founders from initial idea through seed-stage investment and beyond.
Source: firm website, verified Aug 25, 2026.
Team · 42 people
from the firm's website & curated & public directoriesFounder mafia
5 people who came through GENERAL INCEPTION went on to found or lead other companies.
What they invest in
from 31 of 41 portfolio companiesBiotech ×24Deep Tech ×16Medical Devices ×12Healthtech ×10AI & Machine Learning ×7Digital Health ×5Cleantech ×4Hardware ×4
HQs:United States×11France×2Spain×1
Who they back
founder profiles across 8 portfolio companiesFounding team size:solo founder×22 founders×13 founders×34+ founders×2
Investments · 41 tracked
founders shown can be your intro pathBy year:2026 · 12025 · 12024 · 22023 · 15 dated
Switchback Systems develops a benchtop DNA synthesis platform that combines onboard oligonucleotide synthesis and gene assembly, aimed at putting synthetic biology tools directly in scientists' hands.
BiotechDeep TechHardwareSan Francisco Bay Area, US
Board seatCraig Asher· per SEC Form D
Co-investorsAhren Innovation CapitalVertical Venture PartnersOMX Ventures
Biocellis develops a patented bioluminescence immunoassay platform that delivers laboratory-grade, picogram-level sensitivity with results in under 60 seconds in a compact, portable format for point-of-care and high-throughput screening.
BiotechDeep TechMedical Devices
Inapill develops first-in-class, orally available small-molecule therapeutics that target immune cell metabolism to suppress multiple pro-inflammatory cytokines at once.
BiotechDeep TechHealthtech
Greg Timblin(Founder & CEO)Eric Noel(Head of Operations)Kathleen Pestal(Head of Research)
BRAINBox Solutions develops a multi-modality diagnostic approach for mild traumatic brain injury (mTBI), combining blood biomarker panels with tablet-based neurocognitive testing to produce an objective injury score and a prognosis of post-injury symptoms.
AI & Machine LearningBiotechDigital HealthMedical DevicesHouston, US
Steve Wallace(Chief Operating Officer, Global Supply Chain Management)Donna J. Edmonds(CEO)inJames V. Snider(Chief Technology Officer / Advisor)Tim Van Meter(Chief Scientific Officer)Richard Noel(Chief Product and Commercial Officer)Robert Sledd(Director)
Board seatVikram Chaudhery· per SEC Form D · $18.5M raise · filed Nov 2023
Co-investorsAmbit Health VenturesBioventures InvestorsGenoa VenturesVTC Ventures
New York, US
Board seatCraig Asher· per SEC Form D · $52.9M raise · filed Feb 2024
SimBioSys builds AI-powered 3D visualization and diagnostic technology that models tumors as "digital twins" to support individualized cancer treatment planning.
AI & Machine LearningBiotechDigital HealthMedical DevicesChicago, US
John A Cole(Executive Officer)Joe Peterson(Co-founder)John Cole(Co-founder)Tushar Pandey(Co-founder)Joseph Peterson(Executive Officer, Director)Stacey Stevens(Executive Officer, Director)
Board seatVikram Chaudhery· per SEC Form D · $8M raise · filed Jan 2025
Co-investorsAV8 VenturesGenoa Ventures
Linking CRISPR to single cell genomics with DNA-RAM
Alida Biosciences develops EpiPlex, a platform for detecting RNA modifications (m6A, inosine, and pseudouridine) through both turnkey profiling services and in-lab kits, with EpiScout machine-learning software that converts sequencing data into analysis results.
AI & Machine LearningBiotechHealthtechSan Diego, US
John Drewry(Director)Gudrun Stengel(Executive Officer, Director)
Co-investorsFusionX VenturesVertical Venture Partners
Basilard BioTech develops Celletto, a nanomechanical (mechanoporation) gene delivery platform that inserts genes directly into the nucleus of cells without viral vectors, aimed at cell and gene therapy (CGT) developers and manufacturers.
BiotechDeep TechMedical Devices
Co-investorsBand of AngelsPaladin Capital GroupVertical Venture Partners
Novel clinical sample collection from breath
Clearcut Surgical develops a surgical device that combines electrosurgery, continuous smoke evacuation, and on-demand fluid suction in a single instrument.
HardwareHealthtechMedical DevicesBoston, US
Alex Yang(MD)inJeffery John Caputo(Executive Officer, Director)Heung Bae Kim(MD)
Co-investorsLaunchpad Venture GroupMassVentures
Constructive Bio is a biotechnology company that rewrites the genetic code to give cells access to non-canonical amino acid building blocks, expanding the range of proteins that can be designed, engineered, and manufactured.
BiotechDeep TechNew Materials
Jason Chin(Professor)
Co-investors+ND CapitalAmadeus Capital PartnersFine Structures VenturesLongeVCOMX VenturesPaladin Capital Group+2 more
CryoVeritas makes user-activated temperature indicators that integrate both time and temperature to confirm the integrity of vaccines and biospecimens exposed to heat during cold-chain storage down to −200 °C.
BiotechHardwareHealthtech
Co-investorsPaladin Capital Group
Detective Biosciences is developing a blood-based cancer detection test that analyzes patients' DNA epigenetic profiles.
BiotechHealthtechMedical Devices
Dyno Therapeutics develops artificial intelligence-powered genetic technologies for gene therapy, specifically engineering adeno-associated virus (AAV) capsids to improve gene delivery for treating genetic diseases.
AI & Machine LearningBiotechWatertown, US
Eric Kelsic(CEO & Cofounder)inSam Sinai(Vice President, Head of ML & Cofounder)inAdrian Veres(Chief Scientific Officer & Cofounder)George Church(Scientific Cofounder)Tomas Bjorklund(Scientific Co-founder)Alan Crane(Executive Chairman & Cofounder, Polaris Entrepreneur Partner)
Co-investorsAndreessen HorowitzCRV (Charles River Ventures)GV (Google Ventures)Lux CapitalObvious VenturesCasdin Capital+2 more
Eleni Health makes the Pareli Relief Patch, a wearable device worn under clothing over the lower abdomen that delivers heat and transcutaneous electrical nerve stimulation (TENS) to relieve menstrual pain.
Digital HealthFemTechMedical Devices
Ennovate Pharma is an early-stage biotech company developing personalized therapeutic antibodies for autoimmune and inflammatory diseases, focusing on refractory and non-responder patients of current cytokine-based treatments.
AI & Machine LearningBiotechMedical DevicesSaint-Louis, FR
Exodigm develops extracellular organic sensors that monitor the intracellular genomic and transcriptomic content of living cells, allowing researchers to select, track, and study specific cells by their genomic content.
BiotechDeep TechMedical Devices
Hao Yan(Co-founder)Rizal Hariadi(Co-founder)
Hermes Biosciences develops a benchtop extracellular vesicle isolation system that purifies exosomes from bodily fluids and cell culture media for research and clinical applications in oncology, degenerative disease, and regenerative medicine.
BiotechDeep TechMedical Devices
Co-investorsPaladin Capital Group
Bridging the gap between conceptualization and realization
Targeting RNA modifying enzymes in autoimmunity
Kindbody is a fertility care provider offering services such as egg freezing, IVF, IUI, and prenatal and gynecological care through its own clinics across the US.
Digital HealthFemTechHealthtechSan Francisco, US
Dr. Lynn Westphal(Co-founder)Gina Bartasi(Executive Officer, Director)inFahimeh Sasan(Founding Physician / Ob-Gyn)Angeline Beltsos, M.D.(Director)
BoardKathy Harris(Director)inCheryl Pegus(Director)
Co-investorsAnsa CapitalClaritas CapitalGV (Google Ventures)Spice CapitalTMVTq Ventures Llc+3 more
Single-molecule protein sequencing for unbiased high depth proteomics
Origin Peptides develops greener, cheaper, and faster peptide synthesis technology as an alternative to Solid Phase Peptide Synthesis (SPPS), and offers proteomic analysis and consulting services.
BiotechCleantechNew Materials
Partillion generates cell-cell interaction data using Nanovials that co-localize cells in defined microenvironments to measure signaling, activation, binding, and other responses, with live-cell recovery via standard flow cytometry.
AI & Machine LearningBiotechDeep TechLos Angeles, US
Joseph de Rutte(Executive Officer, Director)Dino Di Carlo(Director)Joe de Rutte(Founder)inEric Moessinger(Director)
BoardPaul Conley(Director)
Co-investors+ND CapitalPaladin Capital GroupVertical Venture Partners
Pharmacelera develops computational chemistry software and services for drug discovery, using proprietary 3D molecular field descriptors, quantum mechanics, and AI to screen ultra-large chemical libraries and identify novel, synthesizable compounds.
AI & Machine LearningBiotechDeep TechBarcelona, ES
Enric Gibert(Founder)Enric Herrero(Founder)
Co-investorsCapital CellHeran Partners
Planet Smart develops bio-based, home-compostable superabsorbent polymers (PlanetSorb) that absorb liquid without leaving microplastics.
Circular EconomyCleantechNew Materials
Surf Therapeutics develops a non-invasive broad-beam ultrasound platform that stimulates nerves to activate the body's cholinergic anti-inflammatory pathway, aiming to restore immune balance and treat inflammatory and autoimmune disorders without drugs.
Deep TechHealthtechMedical Devices
Co-investorsCapital FactoryTMC Venture FundSOSVVVP Ignite
SynthBiome designs synthetic growth media that replicate the physiological conditions bacterial pathogens encounter in human infection sites, including media mimicking cystic fibrosis sputum and chronic wound environments.
BiotechDeep TechHealthtech
Tactile Therapeutics is a venture-funded biotechnology company working on Targeted Protein Degradation.
Biotech
Tavira Therapeutics develops an AAV delivery platform for gene therapy that uses modular, post-manufacture enzymatic modification of AAV vectors to target intended tissues more accurately.
BiotechDeep TechMedical Devices
Els Henckaerts(Co-founder)Benjamien Moeyaert(Co-founder)Veronick Benoy(Co-founder)Vibha Kiran Tamboli(Co-founder)Inge Van Hove(Co-founder)
Trench Therapeutics develops live biotherapeutic products derived from research on the nasal microbiome to prevent and treat infectious and inflammatory diseases.
BiotechHealthtech
Cindy Liu(Co-founder)David Harburger(Co-founder)Prashant Girinath(Co-founder)
Developing a vein-to-vein autologous cell therapy manufacturing system
Xera Energy is developing recycling solutions for electric vehicle batteries, targeting the growing volume of battery scrap generated in the U.S.
Circular EconomyCleantechEnergy
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Portfolio news
latest coverage across their companiesSurf Therapeutics · finsmes.com · Apr 13, 2026
Pharmacelera · ddw-online.com · Feb 20, 2026
ClearCut Surgical · gscapitalconnect.substack.com · Jan 26, 2026
Abbelight · finsmes.com · Jan 8, 2026
Constructive Bio · nature.com · Oct 20, 2025
Partillion · insideprecisionmedicine.com · Jun 9, 2025
Frequently asked questions
- How many investments has GENERAL INCEPTION made?
- GENERAL INCEPTION has 38 tracked investments, including 1 dated in the last 24 months.
- What stage does GENERAL INCEPTION invest at?
- GENERAL INCEPTION invests at the Pre-Seed, Seed stages.
- What sectors does GENERAL INCEPTION focus on?
- GENERAL INCEPTION focuses on Biotech, Deep Tech, Medical Devices, Sector Agnostic.
- Where is GENERAL INCEPTION located?
- GENERAL INCEPTION is headquartered in Palo Alto, US.
- Does GENERAL INCEPTION lead rounds?
- GENERAL INCEPTION typically participates in rounds rather than leading them.
- Who does GENERAL INCEPTION co-invest with?
- GENERAL INCEPTION most often shares deals with Vertical Venture Partners, Paladin Capital Group, GV (Google Ventures), among 29 tracked co-investors.
Images
Co-investors · 2
ARCH Venture Partners is a venture capital firm that invests in and helps build transformational companies, with a strong focus on the life sciences and biotechnology sector.
Northpond Ventures is a venture capital firm based in Bethesda, Maryland that invests in life sciences, technology, and related sectors.
Firms observed investing alongside GENERAL INCEPTION, from public investor directories. Shared companies are the overlap with GENERAL INCEPTION's recorded portfolio.
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