National Institutes of Health (NIH) — 2023 Investments

149 Bio develops integrin-targeted therapies for kidney disease, with a lead program (ONT01) that is a Phase 1/2-stage small molecule integrin αMβ2 (CD11b) agonist for lupus nephritis and focal segmental glomerulosclerosis.

AI & Machine LearningBiotechDeep Tech

2Witech Solutions develops sensing products for water monitoring and contamination detection using engineered nanostructures.

CleantechDeep TechNew Materials

ACatechol develops bioinspired surface treatment technologies to prevent infections in medical devices, particularly catheters, by inhibiting biofilm formation.

BiotechHealthtechMedical DevicesNew MaterialsSanta Barbara, US

KAKollbe Ando Ahn(Chief Executive Officer)Phillip Ho(EVP of Product Development)Eric Ryan(Chief Financial Officer)Jin-Soo Ahn(Executive Officer, Director)Byung-Jun Ahn(Executive Officer, Director)

BoardJinsoo Ahn(Clinical Advisor)

Acoustica.bio develops acoustophoretic technology and microgel suspension formulations that concentrate biologic drugs (such as monoclonal antibodies) to ultra-high concentrations exceeding 500 mg/mL for small-volume subcutaneous injection.

BiotechDeep TechMedical DevicesCambridge, US

DFDaniele Foresti(Founder)inDaniele Foresti, Ph.D.(Founder & CEO)Professor Jennifer Lewis(Scientific Co-Founder)

Co-investors3C3CC | Third Culture CapitalSASafar Partners

Adhera develops AI health agents that support families managing pediatric chronic conditions by providing empathic, personalized guidance and care coordination.

AI & Machine LearningDigital HealthHealthtech

Ricardo C. Berrios(Co-founder and Chief Executive Officer)Luis Fernandez-Luque(Co-founder and Chief Scientific Officer)

Alara is a healthcare company focused on improving the safety and quality of healthcare for organizations.

Healthtech

Co-investorsIDID VenturesINInvest Michigan

Allerdia develops a rapid immunosensor-based allergy diagnostic test using its patented Reverse-Lateral Flow ImmunoAssay (R-LFIA) platform, which detects allergic IgE from a small drop of serum or capillary blood within 15 minutes at the point of care.

BiotechDigital HealthMedical DevicesTorrance, US

Allergyamulet develops a portable food allergen and ingredient sensor to help people with food allergies safely identify potential allergens in food before consumption.

ConsumerHardwareHealthtechMedical Devices

Abigail Barnes(Co-Founder & CEO)in

Co-investorsALAllerfund Ventures, LlcCOColle Capital PartnersDIDipalo VenturesGRGreat North VenturesGRGreat Oaks Venture CapitalHEHealthX Ventures+3 more

Anatomy Mapper offers anatomical mapping technology built on language, language-vision, and vision-language models, with a free education version of its product available online.

AI & Machine LearningEdTechHealthtech

AmplifiDx develops point-of-care molecular diagnostic tests and its DX 100 platform for family, women's, and sexual health, targeting infectious disease detection for healthcare professionals and patients.

BiotechDigital HealthFemTechHealthtechMedical DevicesPleasanton, US

NSNancy Schoenbrunner(Chief Executive Officer)inSDShoulian Dong(Chief Scientific Officer)DSDaniel Schoener(Chief Product Officer)CMChris Meda(Chief Commercial Officer)inMing Tan(Director)Sammy Datwani(Director)

Co-investorsAVAvestria VenturesBEBeacon AngelsSOSocial StartsSHShepherd Ventures

Amplified Sciences is a clinical-stage diagnostics company that has developed an ultra-sensitive optical reporter platform for multi-omics diagnostic tests, aimed at helping clinicians detect, treat, and monitor difficult diseases.

BiotechHealthtechMedical DevicesWest Lafayette, US

DCDiana Caldwell(Executive Officer, Director)inVincent Jo Davisson(Executive Officer, Director)

BoardACAndrew Cothrel(Director)inWade Lange(Director)Robert Saunders(Director)

Co-investorsBEBeni Venture CapitalELElevate VenturesGRGravity VenturesHOHouston Angel NetworkIUIU VenturesFLFlywheel Fund+1 more

Appa provides a technology-based mentorship program that pairs teens with vetted, trained mentors and an evidence-based curriculum to build motivation, confidence, and resilience.

Digital HealthEdTechMental Health

SWSean Woodruff(Founder)in

Co-investorsMAMagnify VenturesVEVery Serious VenturesPRProgression

Aprea Therapeutics is a biopharmaceutical company developing novel cancer therapies targeting DNA damage response pathways to treat solid tumors including ovarian, colorectal, prostate, and breast cancers.

BiotechDigital HealthMedical DevicesDoylestown, US

JPJohn P. Hamill(Executive Officer)inOGOren Gilad(Chief Executive Officer, President)in

BoardJean-Pierre Bizzari(Director)Gabriela Gruia(Director)Rifat Pamukcu(Director)Bernd Seizinger(Director)

Co-investors5A5AM VenturesHEHealthCapRORobin Hood VenturesRORosetta Capital Ltd.VEVersant VenturesSOSoleus Capital

Aquillius supports early-stage life sciences companies by connecting them with capital, resources, and expertise to accelerate technology commercialization.

BiotechDeep TechEdTechFintechHardwareHealthtechMedical DevicesSan Diego, US

MyPhuong Le(President)Leah Villegas(Vice President)

Arche XR builds a VR mental health suite of immersive experiences aimed at developing emotional and behavioral resilience.

Digital HealthEdTechMental Health

Armida Labs develops anti-metastatic drug candidates for pancreatic cancer and other solid tumors, using a platform for covalent drug discovery that targets histidine, lysine, or tyrosine residues to induce tumor apoptosis.

BiotechDeep Tech

BAC Stitch DNA is a biotech company that develops DNA sequencing and analysis technology for genomic research and applications.

AgTechBiotechDeep Tech

David Craford(CEO)Sasha Levy(CSO)Gavin Sherlock(Advisor)

Bay Genomics is a Berkeley-based biotechnology services firm offering cell model development, genetic sequence analysis, cell culture, drug testing, and device prototyping (hardware and software) for researchers, startups, and small organizations.

BiotechDeep TechHardwareBerkeley, US

Beaver provides digital support and guidance for family caregivers managing aging loved ones, combining assistive technologies with behavioral science research.

Digital HealthHealthtechLongevityWellness & Fitness

Emily

BioSurfaces develops medical devices, 3D tissue engineering scaffolds, and personal care products using its proprietary Bio-Spun nanofiber technology.

BiotechMedical DevicesNew MaterialsAshland, US

Tina M Phaneuf(Executive Officer and Director of Manager)inMDMatthew D. Phaneuf(Executive Officer and Director of Manager)in

BoardThomas L Barrette(Director of Manager)

Co-investorsBIBill & Melinda Gates Foundation

Bloomer Tech develops digital biomarkers and precision cardiovascular care built around female physiology.

Digital HealthFemTechMedical Devices

ACAlicia Chong Rodriguez(Founder & CEO)inAHAceil Halaby(Founder & COO)in

Co-investorsCACatalytic Impact FoundationMAMaterial Impact

Bold Type helps medtech startups build secure, FDA-compliant software through a team of engineers and cybersecurity experts with deep regulatory experience.

CybersecurityDigital HealthMedical Devices

Jose Bohorquez(CEO & Co-founder)Mohamad Foustok(CTO & Co-founder)Andres Echeverry(COO & Co-founder)

Borrow My Glasses is an education and consulting company that develops training, learning solutions, and evaluation services for organizations serving older adults and caregivers.

EdTechHealthtechLongevityMental HealthWellness & FitnessNew Haven, US

Donna B. Fedus(Gerontologist & Founder)

BRI (Bubbleology Research International) provides environmental measurement, field research, and instrumentation services, combining mobile measurement platforms, high-volume aerosol/bioaerosol sampling, sensor integration, and satellite data fusion for emissions and source characterization.

Climate TechDeep TechHardware

Ira Leifer(Dr.)

Celestial Therapeutics is a biotech company whose team works across genetics, virology, bioengineering, pulmonary surfactant lipid and protein chemistry, innate immunity, infectious diseases, and pharmacology.

BiotechIrvine, US

Leontis Teryazos(CFO and Corporate Secretary)inAjay Gupta(President, CEO and Chairman of the Board)inANNELISE E BARRON(Director)

BoardGeorge Siber(Director)

Co-investorsSTStartX

CellChorus develops a visual AI platform called TIMING that performs high-throughput dynamic analysis of single cells, measuring cell activation, killing, and movement over time for biopharmaceutical research.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesHouston, US

DMDan Meyer(Founder)inNVNavin Varadarajan(Founder)inLCLaurence Cooper(Co-founder & Board Chair)inRBRebecca Berdeaux(Chief Scientific Officer)in

Co-investorsBRBreakout VenturesHOHouston Angel NetworkTETexas HALO FundY Y CombinatorASAsymmetry Ventures

Austin, US

Stephen Edward Popovich(Executive Officer)

ClearVoya is a company associated with interventional neuroradiology, led by a physician specializing in minimally invasive brain, head/neck, and spine procedures.

HealthtechMedical Devices

Sameer A. Ansari(CEO & Co-Founder)

Clinic Chat builds AI-powered chatbots that use machine learning and natural language processing to encourage health screenings, appointment scheduling, and behavior change for people with or at risk for infectious and chronic diseases.

AI & Machine LearningDigital HealthHealthtech

HealthtechRoanoke, US

JSJohn Schmedtje(Executive Officer)in

Cove Technology is a consulting firm offering hardware and embedded systems engineering services, including system design, embedded development on microcontrollers and FPGAs, and Apple MFi program navigation.

Deep TechDeveloper ToolsHardware

HealthtechNorth Chicago, US

John Alverdy(Director)Jamie Contreras(Director)Peter Farmakis(Executive Officer, Director, Promoter)Brian Yoor(Director)

Cyberdontics develops a handheld intraoral scanner using OCT imaging plus AI-based diagnostics and treatment planning, along with a dental robotics system intended to perform restorative procedures such as crowns and fillings faster and more accurately.

AI & Machine LearningMedical DevicesRobotics

DCDr. Chris Ciriello(Founder)in

Co-investorsTATaihill Venture

Duo Oncology is a clinical-stage company developing tumor-activated prodrug combinations intended to replace toxic multi-agent chemotherapy with single medicines that concentrate activity in tumors.

BiotechHealthtechPittsburgh, US

SLSONG LI(Director, Promoter)JING-ZHOU HOU(Executive Officer, Director, Promoter)SRSam Rothstein(CEO & Cofounder)inKEKatherine Eichinger(Chief Operating Officer)STSTEPHEN THORNE(Executive Officer, Promoter)in

BoardJOE GATTO(Director)in

Co-investorsULUlu VenturesINInnovation WorksNUNuFund Venture Group

Eitr Bio develops single domain antibody-based immunotherapeutics through its Orthogonal Dual-Interacting Nanotherapeutic (ODIN) platform, including small bispecific molecules designed to penetrate solid tumors, gram-negative bacteria, and viral reservoirs in deep tissues.

BiotechDeep TechHealthtech

Elgia Therapeutics is a biopharmaceutical company developing novel molecular therapies for metabolic, inflammatory, and fibrotic diseases.

BiotechHealthtechSan Diego, US

Michael KarinMichelle ArkinAdam RensloBrian Hubbard(Director)Alan Saltiel(Executive Officer, Director)Thomas Coll(Executive Officer)

Elysium develops healthcare products focused on aging research and healthy aging rather than disease treatment.

HealthtechLongevityWellness & FitnessNew York City, US

LGLeonard Guarente, Ph.D.(Co-founder & Chief Scientist)DADan Alminana(COO, co-founder)inEric Marcotulli(CEO, co-founder)inJason AndersoninLeonard Guarente, PhD(Co-founder & Chief Scientist)

Co-investorsBRBreyer CapitalGAGaingelsSPSprint VcTHThe Venture CollectiveWEWestern Technology InvestmentOSOS Fund

eMedicalSentry provides remote patient monitoring (RPM) and telehealth services that let hospitals and healthcare providers track and communicate with patients remotely to reduce 30-day readmissions and avoid Medicare penalties.

Digital HealthHealthtechMedical Devices

Co-investorsMAMaryland TEDCOTETEDCO

Alborz Yazdi(Founder)in

Co-investorsGAGaingels

Formation Venture Engineering is a venture capital and advisory firm focused on founding and scaling life science companies, particularly in therapeutics, diagnostics, and platform technologies with emphasis on neurology.

BiotechDeep Tech

Rahul(Managing Partner and Co-Founder)Gary Magnant(Co-founder and General Partner)

GelSana Therapeutics develops zwitterionic polymer-based biomaterials for wound care, addressing excess sustained inflammation that impedes healing.

BiotechHealthtechMedical DevicesNew MaterialsAurora, US

MKMelissa Krebs(Founder and CEO)inDGDonald Gregg(Chief Commercial Officer)inARAdam Rocker(Director R&D)inVAVicki Abbas(Executive Director Clinical Operations)inACAnia Camplin(Fractional CFO)in

BoardMFMike Freeman(Director)in

Co-investorsINInnosphere VenturesBOBoulder VenturesCOColorado BioScience AssociationMIMINES VENTUREPLPlug and Play Ventures

GenMedPro is a genetics-based medication management platform that analyzes 26 genes to identify drug-drug and gene-drug interactions across a patient's entire medication regimen.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesKing of Prussia, US

Dr. Ronald Dozoretz(Founder)SHStephen Haller(Executive Officer)Gloria Nuss(Executive Officer)Beth E. Dozoretz(Executive Officer, Director)THThomas Hess(Executive Officer)inMichael Koffler(Executive Officer, Director, Promoter)

Co-investorsCLClaritas Capital

GMJ Techs develops analytical instruments that combine capillary electrophoresis with optical and mass spectrometry detection for bioanalytical applications.

BiotechDeep TechHardwareMedical DevicesSeattle, US

Carol Berry(CEO)Tosin Dada(President & CTO)

Greenstone develops induced pluripotent stem cell (iPSC)-based non-animal models combined with AI for drug discovery and development.

AI & Machine LearningBiotechDeep TechStanford, US

Dr. Joseph C. Wu(Co-founder)

Co-investorsWAWalden Catalyst

HaptX develops wearable haptic gloves and related technology that enable realistic touch simulation in virtual reality, spatial computing, and robotics applications.

Deep TechHardwareRobotics

JRJake RubininDr. Bob Crockett(Co-founder)

Co-investorsKEKeiretsu ForumCRCRESCENT COVE CAPITALTATaylor Frigon Capital PartnersVEVerizon Ventures

Hats & Ladders provides a digital career exploration curriculum and platform for K-12 students to discover career pathways, develop workplace skills, and plan their educational and professional futures.

Creator EconomyEdTechFuture of WorkSaaS

Leah Potter(President & Co-Founder)David Langendoen(CFO & Co-Founder)Scott Brewster(Director of Partnerships & Co-Founder)

Healcisio develops AI-driven clinical decision support systems for hospitals, including sepsis prediction, quality reporting automation, and outpatient monitoring.

AI & Machine LearningDigital HealthHealthtech

Michael McCurdy(MD)Hayden PourJennifer AttiasGeorgia PoirierNabil AsadiNeha Shashikumar

Heligenics is a genomics and cell biology company that develops assays and platforms for drug screening and genetic analysis.

AI & Machine LearningBiotechDeep TechMedical DevicesLas Vegas, US

Martin Schiller, Ph.D.(Founder & CEO)Lawrence John Loomis(Chief Operating Office & Corporate Secretary)Martin Schiller(Executive Officer)

Helixomer is a preclinical RNA nanodrug company developing fully synthetic, reversible anticoagulants and reversal agents to replace heparin in acute critical care.

BiotechDeep TechHealthtechResearch Triangle Park, US

Henley Ion develops patented miniaturized Electrostatic Precipitator (mEP) technology used in respiratory protection and air purification systems designed to protect against nuclear, biological, and chemical contaminants as well as toxic industrial materials.

CleantechHardwareHealthtech

Julian Henley(Founder)

HydroCision develops minimally invasive surgical instruments using proprietary FluidJet technology to selectively remove soft tissue in a precise manner.

BiotechHardwareHealthtechMedical DevicesNorth Billerica, US

PAUL KOWALSKI(Executive Officer)inRICHARD A. LYTLE, III(Executive Officer, Director)TDTHOMAS D. ABERT(Executive Officer)inPATRICIA VANBLARCOM(Executive Officer)RLRick Lytle(President & Chief Executive Officer)in

BoardLONG ZHAN(Director)

Co-investorsBIBioVenturesNENewbury VenturesOXOxford Bioscience Partners

iMetabolic Biopharma Corporation develops pharmaceutical candidates targeting metabolic and lipid-related disorders, including obesity, cardiovascular disease, and neurodegenerative conditions.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Urban A. Kiernan(Dr.)

Inovodel develops a compact, portable system for generating and delivering inhaled nitric oxide to treat pulmonary conditions including pulmonary hypertension and hypoxic lung failure.

BiotechDeep TechHealthtechMedical Devices

InsiteHub provides learning technology solutions and consulting services for organizations in life sciences and healthcare industries, focusing on enterprise learning strategy, digital transformation, and workforce development.

EdTechEnterprise SoftwareHealthtechHR TechSaaSNewark, US

John Royer(CEO/Managing Partner)

Intact Therapeutics develops next-generation biopharmaceutical therapies for gastrointestinal diseases to address unmet clinical needs.

BiotechHealthtechSan Francisco, US

RPRavi Pamnani(CEO)inSSSidhartha Sinha(Founder)inNavdeep Kaur(Director of R\u0026D)

Co-investorsBRBrightstone Venture CapitalY Y CombinatorHAHanmi HealthcareSTStanford UniversityVEVenture Investment Associates

Co-investorsTRTribes Ventures

Isabl develops whole genome and transcriptome sequencing technology for cancer diagnosis, delivering comprehensive genomic profiling and treatment options to physicians and research teams.

BiotechDigital HealthHealthtechMedical DevicesNew York City, US

JMJuan Medina(CTO and Technical Co-founder)inAKAndrew Kung(MD PhD, Medical Co-Founder)inEPElli Papaemmanuil(PhD, CEO and Scientific Co-founder)in

Co-investorsY Y CombinatorBOBoxOne VenturesTWTwo Sigma VenturesEVEvolution VC PartnersSASand Hill AngelsAMAmino Capital+1 more

Kairos Research conducts applied research on human-AI collaboration and cognitive systems for clients in commercial, academic, and government sectors.

AI & Machine LearningDeep TechDefense TechDayton, US

Dr. Brandon (Brad) Minnery(Founder and CEO)Ebi Maki(Co-founder and COO)

BiotechSeattle, US

Jonathan Himmelfarb(Executive Officer, Director)Buddy Ratner(Executive Officer, Director)

Lazarus 3D uses a patented soft-tissue 3D printing process to produce anatomically accurate, operable surgical models that let surgeons rehearse patient-specific procedures before operating.

Advanced ManufacturingBiotechHealthtechMedical DevicesHouston, US

JEJACQUES ERIC ZANEVELD(Executive Officer, Director)Dr. Jaques Zaneveld, Ph.D(Founder & CEO)JZJacques Zaneveld(Founder)inDr. Jacques Zaneveld(Founder)Cheri Waddell(Vice President of Pre-Sure Products)Brian Patch(Chief Operating Officer)

Co-investorsRERevolution

Lightswitch Bio develops photoactivated chemotherapy treatments using laser-precision technologies to reduce side effects for cancer patients.

BiotechDeep TechHealthtechMedical DevicesRichmond, US

Limber Prosthetics builds 3D-printed prosthetic devices and a digital scan-design-fabricate workflow for orthotics and prosthetics (O&P) clinicians.

HardwareHealthtechMedical DevicesSan Diego, US

Luca DeVivo Nicoloso(Executive Officer, Director)inJSJoshua Stephen Pelz(Chief Executive Officer, Co-founder)HBHerb Barrack(Chief Clinical Officer, Co-founder)inLuca De Vivo Nicoloso(Co-founder, Board Advisor)inHerbert Joseph Barrack(Executive Officer, Director)WWWalker White(Executive Officer)in

Luciole Pharma is a biotech company focused on metabolic and inflammatory diseases through mitochondrial-targeted therapeutics.

AI & Machine LearningBiotechDeep TechHealthtechLongevityNatick, US

Dennis Goldberg, PhD(President and CEO, Director, Co-founder)Bill Rumsey, PhD(Vice President and CSO, Director, Co-founder)Eric Morrel, PhD(Vice President and COO, Director, Co-founder)Dennis I. Goldberg(Chief Executive Officer)Dr. Lloyd

Metabolon provides metabolomics services and bioinformatics tools that measure small molecules to give biological context to research data.

AI & Machine LearningBiotechHealthtechDurham, US

John A. Ryals(Executive Officer, Director)inGerald M. Haines II(Executive Officer)RFRohan F. Hastie(Executive Officer, Director)inJohn Ryals, Ph.D(Founder)Rohan (Ro) F. Hastie, Ph.D.(President & Chief Executive Officer)

BoardJohn Oxaal(Director)

Co-investorsCACamden PartnersESEssex Woodlands Healthcare PartnersHAHavencrest Capital ManagementRERevelation PartnersSYSyngenta Group Ventures

The Ionique Manual Platform is an ion source replacement for mass spectrometry instruments that enables switching between multiple ionization methods including electrospray ionization and matrix-assisted ionization.

AI & Machine LearningBiotechData & InfrastructureDeep TechHardwareMedical DevicesPhiladelphia, US

Charles McEwen(President and Co-founder)Sarah Trimpin(CEO and Co-founder)Milan Pophristic(CTO)

Nephrogen develops AI-powered AAV delivery vehicles for genetic medicines targeting kidney and pancreatic diseases.

AI & Machine LearningBiotechData & InfrastructureHealthtechMedical DevicesNew York City, US

DMDemetri Maxim(Founder and CEO)Demetri M.(Founder)inVBVivek Bhalla(Chief Medical Officer)

Co-investorsCHChicago Early Growth Ventures (CEGV)GAGaingelsNANational Kidney Foundation, Inc.NONovogenia GmbHSTStartXTETechstars+15 more

NeurAegis is a biotechnology company focused on discovering and developing therapies for neurodegeneration, leveraging research into calpain-2 protease inhibitors.

BiotechHealthtechMedical Devices

Michel Baudry(Founder & Chief Scientific Advisor)Stella M. Sung(President & CEO)

neuro42 develops a portable, FDA 510(k)-cleared MRI platform that brings neurological imaging directly to the patient rather than requiring transport to a facility.

Deep TechHealthtechMedical DevicesSan Francisco, US

AVAmit Vohra(Executive Officer, Director)inABAbhita Batra(Executive Officer, Director)Shibu Gangadharan(Executive Officer)

BoardKrishna R. Bhupal(Director)Rahul Talwar(Director)

Co-investorsFRFrontier Path VCSHShangBay Capital LLCSOSonder Capital

NeuroGevity develops a sleep headband with biometric sensors and AI algorithms to assess brain health and detect neurophysiological biomarkers at home.

AI & Machine LearningBiotechDigital HealthHardwareHealthtechWellness & FitnessSanta Fe, US

Karen Crow(Executive Officer, Director)inBarry Jason Worchel(Executive Officer, Director)

Co-investorsTETechstars

Neuronoff develops Injectrode, a needle-delivered electrode platform for minimally invasive neuromodulation to treat chronic pain and neurogenic bladder in spinal cord injury patients.

AI & Machine LearningHealthtechMedical Devices

Manfred Franke, PhD(CEO & CO-FOUNDER)Andrew Shoffstall, PhD(CSO & CO-FOUNDER)

NFlection is a biopharmaceutical company developing novel therapeutics.

BiotechMedical DevicesBoston, US

CPChristopher Powala(Chief Development Officer, Former President & CEO)Mark de Souza(Executive Officer, Director)in

BoardCorey Goodman(Director)KPKetan Patel(Director)in

Co-investorsF-F-Prime CapitalVEvenBio PartnersVEvenBio Global Strategic

NXT Biomedical is a medical device incubator that develops and spins out startups building clinical medical technologies aimed at addressing unmet needs and reducing healthcare costs.

BiotechHealthtechMedical DevicesIrvine, US

Stanton Rowe(CEO)inDon Bobo(Director)

BoardKadhiresan V Kadir(Director)AEAndrew ElBardissi(Director)inSteven Hochberg(Director)Andrew Cleeland(Director)

Co-investorsDEDeerfield Management Company

Nytricx develops biomedical devices and materials leveraging nitric oxide chemistry and fiber optic technology for wound healing, catheter applications, and extracorporeal circuits.

BiotechDeep TechHealthtechMedical DevicesHoughton, US

Ronald Shebuski(President and CEO)

ORRxD is a preclinical drug discovery company that uses structure-based, high-performance-computing-driven virtual high-throughput screening for hit discovery, along with medicinal chemistry and biological validation.

AI & Machine LearningBiotechDeep Tech

OCMS Bio develops immunology-based technology for vaccine and infectious disease applications.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesKing of Prussia, US

Scott Dessain(Founder and Chief Scientific Officer)Thomas Halpern(COO)Onne Ganel(Business Development)

OmegaQuant is a CLIA-certified laboratory offering fatty acid testing services, including Omega-3 Index, Prenatal DHA, and Mother's Milk DHA tests to researchers, clinicians, and consumers.

Digital HealthHealthtechMedical DevicesWellness & FitnessSioux Falls, US

Bill Harris(Founder, Former President)Jason Polreis(CEO)Kristina Harris Jackson

Opsin Biotherapeutics develops gene therapies to treat chronic pain by converting pain-blocking neurons into photoreceptors that can be activated with red LED light.

BiotechDeep TechDigital HealthHealthtechMedical Devices

Bob Benkowski(CEO and co-founder)Dr. Mohanty(co-founder)

Origami Therapeutics is a preclinical-stage biopharmaceutical company developing protein degrader therapeutics to treat neurodegenerative diseases, starting with Huntington's disease.

BiotechDeep TechHealthtechMedical DevicesSan Diego, US

BHBeth Hoffman(Founder)inLSLeslie Schulze(Co-Founder and CFO)in

Co-investorsY Y CombinatorAJAJGIMImpact Assets

OrthoPreserve develops a minimally invasive meniscus implant for orthopedic care, designed to address unmet clinical needs in knee surgery.

BiotechHealthtechMedical DevicesHenrico, US

JSJonathan Schwartz(Chief Executive Officer)inCKCyrus Kump(Chief Medical Officer)

Co-investorsATAtlanta Technology Angels

Otis Dental offers bruxism (teeth grinding) relief products with a focus on the connection between mental and oral health.

ConsumerDigital HealthDirect to ConsumerHealthtechWellness & Fitness

Pacific Optica develops optical and photonic components including objectives, scan lenses, and imaging systems for applications in neuroscience research, bioengineering, clinical investigations, and advanced manufacturing.

BiotechDeep TechHardwareMedical DevicesSanta Barbara, US

Spencer LaVere Smith, Ph.D.(CEO)Che-Hang Yu, Ph.D.(Engineering)Ryan P. McGreal, M.S.(Operations)

BiotechPhiladelphia, US

Yi Xing(Director)Mingfu Zhu(Executive Officer, Director)Jimmy Lu(Director)

Co-investorsWIWI Harper Group

PATH2Caregiving develops resources and support for caregivers and individuals with disabilities, with a focus on rehabilitation nursing and care coordination.

Digital HealthHealthtechSocialWellness & Fitness

Michelle Camicia(Co-founder)Barbara Lutz(Co-creator)

PATH to Reading is a patented brain-training web application that accelerates visual processing and motion perception to improve reading fluency, attention, and memory in children and adults with dyslexia, reading difficulties, and cognitive impairments from concussions or aging.

AI & Machine LearningDigital HealthEdTechHealthtechSan Diego, US

Dr. Teri Lawton

Perosphere is a medical technology company developing point-of-care coagulation diagnostics, including a pharmacodynamic test that provides a global view of a patient's coagulation status.

BiotechHealthtechMedical DevicesDanbury, US

Sasha Bakhru(Founder)inSolomon Steiner(Director)Michelle Brennan(Director)Daryl Mootoo(Executive Officer)Bakhru Sasha(Executive Officer, Director)Mark Pavao(Director)

Co-investorsCOConnecticut InnovationsAMAmbit Health Ventures

Pilltrax develops tools to support medication adherence and chronic disease self-management for patients between clinical visits, including a virtual adherence assistant and a patented pillbox.

Digital HealthHealthtechMedical Devices

Alvin Ramsey(Founder & Technical Lead)Maria Venegas(Domain Expert on Community-Based Participatory Research)Wes Rutledge(Operations Lead)

Pirouette develops self-injection devices for chronic condition management at home, featuring hidden-needle technology to reduce injection anxiety.

BiotechHardwareHealthtechMedical DevicesNew Hampshire, US

Conor Cullinane(Co-Founder, Chairman, CEO, President, Principal Investigator)Matthew J. Kane(Co-Founder, Secretary, and Chief Operating Officer)Elijah Kapas(Co-Founder and Chief Technology Officer)MKMatthew Kane(Founder)in

Co-investorsGAGaingelsLILiquid VenturesSASafar PartnersY Y CombinatorHEHelium-3 Ventures

PRO Therapeutics is an early-stage regenerative medicine company developing a platform for soft tissue repair that regenerates tendons, ligaments, and muscles, with an initial off-the-shelf graft product aimed at rotator cuff tendon-to-bone repair.

BiotechHealthtechMedical DevicesManchester, US

Procyon Technologies develops immunoisolation cellular therapies and implantable devices for medical applications including diabetes and other conditions.

BiotechDeep TechHealthtechMedical Devices

Klearchos Papas(Co-founder, Ph.D.)Robert C. Johnson(Co-founder)

Promakhos Therapeutics develops immunomodulatory therapies to restore immune system balance and reduce chronic inflammation in diseases like Crohn's disease, ankylosing spondylitis, and psoriasis.

BiotechHealthtechBoston, US

KCKaterina Chatzi(Founder)inJEJasper Edgar Neggers(Founder)inAIKATERINI CHATZI(Executive Officer, Director, Promoter)KCKaterina Chatzi, PhD(Founder)in

Co-investorsFOFoundersGAGaingelsMEMetaplanetPIPioneerY Y CombinatorZAZAKA VC+7 more

Co-investorsOSOssian Capital

PG Pharma develops CBD-based pain relief medicines, including water-soluble sublingual tablets aimed at treating diabetic neuropathic and osteoarthritic inflammatory pain.

BiotechHealthtech

REST Technologies develops technologies for the field of sleep medicine, aiming to expand diagnostic and treatment services for patients with sleep disorders such as insomnia, sleep apnea, restless legs syndrome, and narcolepsy.

Digital HealthHealthtechMedical Devices

Jerald H. Simmons(Founder)

Revel Pharmaceuticals develops enzyme-based therapeutics designed to recognize and reverse molecular damage that accumulates in the body's structural tissue — collagen, elastin, and extracellular matrix — targeting age-related damage that drives disease.

BiotechDeep TechLongevitySan Francisco, US

ACAaron Cravens(Co-Founder & CEO)inJCJennifer Cochran(Director)

Co-investorsGAGaingelsLOLong Game

Rip Road develops a patient tracking platform built on SMS and mobile technology for patients managing complex therapies and chronic conditions.

Digital HealthHealthtechSaaSNew York, US

SMS and mobile data pioneers from AT&T Wireless

Rock by Rock provides project-based learning experiences designed to help students develop real-world problem-solving skills and agency.

EdTech

JeffSung-Ae

S-3 Research develops digital tools using machine learning and data science to increase young adult participation in clinical trials.

AI & Machine LearningData & InfrastructureDigital HealthHealthtechFullerton, US

Tim Mackey(Co-PI)

Saavsus develops evidence-based educational and health programs delivered through digital platforms and print materials, serving K–8 schools, early childhood programs, and transition educators.

EdTechHealthtechImpact & Social GoodSaaSSocialEugene, US

SanaHeal develops soft-material and bioadhesive technologies, such as hemostatic and tissue-regeneration solutions, for medical device applications.

BiotechHealthtechMedical DevicesNew Materials

Hyunwoo Yuk(Founder & CTO)Patrick Rivelli(President & CEO)

Co-investorsARArcherman CapitalFUFuturePlayTATaihill VentureTHThe E14 Fund

Sano Healthcare develops technologies and systems to improve healthcare access, delivery, and quality for diverse populations.

Digital HealthHealthtechMedical DevicesOntario, US

The company develops cancer immunotherapy treatments.

AI & Machine LearningBiotechHealthtech

RJRich Johnson(Co-Founder, VP of Development)inDominique Kendrick(Co-Founder, SVP of Regulatory Affairs)Prof. James Moon(Co-Founder, Chief Scientific Officer)Prof. Yu Leo Lei(Co-Founder, Clinical and Pre-Clinical Advisor)RPRobert Petit(Co-Founder, Clinical and Pre-Clinical Advisor)inMatthew Martin(Co-Founder, Partner at Pathway Bioventures)

Co-investorsSMSmartHealth Catalyzer

BiotechDurham, US

Robert Black(Director)Lesco Rogers(Director)Steven Bischoff(Director)Lanty L Smith(Executive Officer, Director, Promoter)

Co-investorsNCNC IDEA

Vivid Vision builds a vision care platform that uses virtual reality technology to treat conditions such as amblyopia and strabismus.

Digital HealthHealthtechMedical Devices

James(Founder)Manish(Co-founder)

Co-investorsCOColopl NextGUgumi IncSOSoftTech VCSOSOSV

Siloam Vision develops medical imaging and software solutions for eye care, with initial focus on retinopathy of prematurity (ROP) in premature infants.

AI & Machine LearningHealthtechMedical DevicesPortland, US

DPDr. Pete Campbell(Founder)Dr. Paul Chan(Founder)John Peter Campbell(Executive Officer, Director)Tong Sun(Executive Officer)RVRobison Vernon Paul Chan(Executive Officer)Karyn Jonas(Executive Officer)in

Co-investorsIDIdeashipILIllinois Ventures

Smart Information Flow Technologies (SIFT) is a research and development consulting company working in natural language processing, automated planning, cybersecurity, supervisory control, healthcare, and human-automation interaction.

AI & Machine LearningCybersecurityDeep TechMinneapolis, US

Fort Collins, US

Robert Calvin Goforth(Director)Michael Artinger(Executive Officer, Director)

Spike Neuro develops advanced neural probes and surface array technologies for neuroscience research, enabling academic and commercial researchers to conduct high-quality electrophysiology studies for brain-computer interface and medical device development.

BiotechDeep TechHardwareHealthtechMedical DevicesAnn Arbor, US

Lawrence Savoy(Chief Executive Officer)Charla Howard(Chief Clinical Officer)Rebecca Gerth

HealthtechSan Francisco, US

ALEXANDER MARSON(Executive Officer, Director)PATRICK DAVID HSU(Director)JACOB CORN(Director)

BoardBBBLAKE BYERS(Director)in

Co-investorsTETeam Builder VenturesGVGV (Google Ventures)MAMagnetic Ventures

Sus Clinicals provides preclinical testing services using its Oncopig cancer model, a large-animal platform that induces tumors and other diseases on demand to generate predictive data for medical devices, drugs, and diagnostics.

BiotechDeep TechHealthtechCincinnati, US

Lawrence Schook(Founder)inDr. Jessicca M. Rege(Chief Executive Officer)Stephen J Baggott(Executive Officer, Director)Geoffrey T Marshall(Executive Officer, Director)Jeffrey D Weedman(Executive Chair & Co-Founder)

Teen Health Research develops online, evidence-based sexual and relationship health programs for adolescents.

Digital HealthEdTechHealthtechWellness & FitnessRaleigh, US

Dr. Laura Widman(Founder & CEO)

TSI develops mobile phone-based software for capturing and analyzing heart and lung sounds through auscultation, making diagnostic information available to healthcare providers in remote, resource-limited, and humanitarian settings.

AI & Machine LearningDigital HealthHealthtechMedical Devices

David Wolfson(CEO)

BiotechAustin, US

Brian Windsor(Executive Officer, Director)Kirk Coleman(Executive Officer)Robert S. Mills, Jr.(Executive Officer, Director)Aaron Fletcher(Director)

Thyreos develops recombinant herpesvirus-based vaccines for both animal and human health applications, designed to generate immune responses without affecting the nervous system.

BiotechHealthtechMedical Devices

Co-investorsINInvest Nebraska

Tocagen is a clinical-stage biotechnology company developing cancer-selective gene therapies designed to activate a patient's immune system against their own cancer.

BiotechHealthtechSan Diego, US

Harry Gruber(Executive Officer, Director)Thomas Darcy(Executive Officer, Director)Dennis Berman(Executive Officer, Director)Douglas Jolly(Executive Officer)

BoardFaheem Hasnain(Director)Lori Kunkel(Director)

Co-investorsBIBioBrit

Trace Biosciences develops technology to make nerves visible in real time during surgical procedures, enabling surgeons to better identify and preserve nerve structures.

BiotechDeep TechHealthtechMedical DevicesBeaverton, US

Connor Barth(Cofounder & CEO)inSummer Gibbs(Cofounder & CSO)Lei Wang(Cofounder & CTO)Jonathan Sorger(Director)

Co-investorsELElevate CapitalSCSciFounders

Reddy Book is an online platform for sports betting and live casino gaming, covering cricket (including IPL), football, tennis, and casino games such as Teen Patti, Blackjack, Roulette, and Baccarat.

ConsumerGaming

Co-investorsCHChaos VenturesGOGood Startup

Urban Design 4 Health (UD4H) is a research, development, and consulting firm that connects urban planning, transportation, and public health, offering consulting services, data analyses, and predictive modeling to public and private organizations.

AI & Machine LearningGovTechHealthtech

Virtus Therapeutics is a biotechnology company developing therapies for genetic disorders, with its first target being PKAN (Pantothenate Kinase-Associated Neurodegeneration).

BiotechHealthtech

Choukri Ben Mamoun(John F. Enders Professor of Medicine (Infectious Diseases), Microbial Pathogenesis and Pathology, Yale School of Medicine)

VitaKey is a precision delivery platform that increases the nutrient density of everyday foods and beverages, applying pharmaceutical-level science to nutrition.

BiotechFoodTechWellness & Fitness

Robert S. Langer(Co-founder)

Volver Health develops technology solutions to improve access to substance abuse treatment and recovery resources for Hispanic and Latinx communities in the United States.

Digital HealthHealthtechMental HealthWellness & Fitness

Wicked Sheets manufactures moisture-wicking bed sheets and pillowcases made from silk-weight polyester designed for consumers seeking improved sleep through better moisture management and airflow.

Advanced ManufacturingConsumerDirect to ConsumerE-commerceHardwareHealthtechWellness & FitnessLouisville, US

ATAlli TruttmanninALLISON M. TRUTTMANN(Executive Officer, Director)

BoardBOB GORMAN(Director)MIKE PARADIS(Director)OMOSCAR MORALEZ(Director)inRANDALL J. BUFFORD(Director)

Co-investorsELElevate VenturesKEKeyhorse Capital

BiotechWayne, US

GNGodfrey Nazareth(President, CEO, Secretary & Treasurer)inMatthew Maltese(Director)

X-Therma develops a proprietary peptoid-based technology that inhibits ice crystal formation to enable long-term sub-zero preservation and transport of cells, tissues, organs, and other biologics.

BiotechDeep TechMedical DevicesNew MaterialsRichmond, US

XWXiaoxi Wei(Founder & CEO)inMKMark Kline(Executive Officer, Director)inJohannes Weggemann(Director)

Co-investorsAUAurum Venture PartnersDEDellin InvestmentsLILIFTTMEMethuselah FoundationMEMethuselah FundsPOPortfolia+2 more

XyloCor Therapeutics develops gene therapies for advanced coronary artery disease and cardiac damage.

BiotechHealthtechMedical DevicesMalvern, US

RCRonald Crystal(Founder and Advisor (Board Observer))TRTodd Rosengart(Founder; Board Observer)JTJohn Tucker(President and CEO)Albert Gianchetti(Executive Officer, Director)

BoardGBGlenn Batchelder(Director)inJames Cohen(Director)

Co-investorsLULumira VenturesFOFountain Healthcare PartnersJEJeito CapitalLOLongwood FundSOSofinnova Ventures

Yali develops fermentation technology to produce sustainable fats and lipids for alternative dairy products like ice cream, butter, and milk, using fewer inputs than conventional sources.

BiotechCleantechClimate TechFoodTech

Co-investorsFIFirst In VenturesFTFTW VenturesS2S2G InvestmentsCRCRCM VenturesTHThird Kind Venture Capital

Zeteo Tech develops mass spectrometry and detection technologies for biomedical, defense, and security applications, including bioaerosol detection and breath analysis.

BiotechDeep TechDefense TechMedical DevicesSykesville, US

CJCharles J. Call(Executive Officer, Director)inWayne Bryden(President and CEO)inTMTom McCreery(VP, Innovation / Chief Innovation Officer)inMMMike McLoughlin(VP, Research / Chief Technology Officer)SFSusan Furney(Chief Operating Officer)JCJerry Carlisle(Chief Financial Officer)

Co-investorsANAnzu PartnersCOCottonwood Technology Fund