Two Bear Capital
Venture capitalActively deployingWhitefish · Pre-Seed–Series B · 35 people tracked
Find your way into Two Bear Capital
2,499 people in our graph share verified history with the Two Bear Capital team — schools, employers, funds. One of them is your warm intro.
Investment thesis
Two Bear Capital invests in founders with breakthrough ideas aimed at solving urgent and complex problems by leveraging both life sciences and technology. The firm focuses on disruptive sectors where these two domains intersect, seeking opportunities where scientific and technological breakthroughs can scale. Its team is composed of investors, operators, and advisors with deep domain expertise across technology and life sciences. Two Bear Capital emphasizes partnering closely with founders to help transform ambitious ideas into enduring, transformative companies capable of delivering impact on a world-changing scale.
Source: firm website, verified Aug 3, 2026.
Team · 35 people
from the firm's website & public directoriesWhat they invest in
from 26 of 28 portfolio companiesAI & Machine Learning ×13Biotech ×12Deep Tech ×8Data & Infrastructure ×7Enterprise Software ×7Healthtech ×7Cybersecurity ×6Cloud Computing ×4
HQs:United States×21
Who they back
founder profiles across 16 portfolio companiesFounding team size:solo founder×82 founders×64+ founders×2
Where their founders studiedfrom 17 founders with education data
University of Idaho ×2Willamette University ×2
What their founders studiedfrom 23 founders with field-of-study data
Life Sciences ×7Computer Science ×5Chemistry ×4Engineering ×4Physics ×3Business & Management ×2Economics ×2Mathematics & Statistics ×2
Where their founders worked beforefrom 24 founders with career history
Stanford University ×4University of Montana ×4Broad Institute ×2GSK ×2Juniper Networks ×2Sandia National Laboratories ×2
13 founders hold a PhD · 1 hold an MBA (of 23 with degree data)
Investments · 28 tracked
founders shown can be your intro pathBy year:2026 · 22025 · 52024 · 52023 · 12022 · 42021 · 22020 · 12015 · 121 dated
CIQ is an enterprise infrastructure software company that builds and supports the Linux, HPC, and AI infrastructure stack from the kernel to the orchestrator, serving enterprises, research institutions, and government agencies.
AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsReno, US
Gregory Kurtzer(Founder & CEO)inBjorn Hovland(President)inPeter Nelson(Chief Technology Officer)inMarlin Prager(CFO)in
Co-investorsRho Capital PartnersRho Ventures
Inimmune is a clinical-stage biotech company developing immunotherapies for allergy, cancer, infectious, and autoimmune diseases.
AI & Machine LearningBiotechDeep TechHealthtechWhitefish, US
Jay EvansinDavid BurkhartinHelene Bazin-LeeinKendal Ryterinalan joslynin
Sanavia discovers novel cancer-specific epitopes using proprietary immunization technology and AI to enable more effective antibody therapies for oncology.
AI & Machine LearningBiotechDigital HealthHealthtechMedical Devices
Arch builds agentic AI that acts as a virtual factory expert, analyzing manufacturing data to identify root causes and give operators, engineers, and shift leaders prescriptive next steps in real time.
Advanced ManufacturingAI & Machine LearningIoTPalo Alto, US
Andrew Scheuermann(CEO & Co-founder)inTim Burke(CTO & Co-founder)inJennifer Davis(Chief Operating Officer)inBen Freeman(SVP of Engineering)inGus Shahin(Director)
Board seatMichael Goguen· per SEC Form D
Co-investorsCapmontComet LabsHCVCMerus CapitalNeotribe VenturesTeam Builder Ventures+2 more
Elisity provides an identity-based microsegmentation platform that turns existing network infrastructure (Cisco, Arista, Aruba, Juniper switches and Palo Alto firewalls) into policy enforcement points to discover devices and enforce least-privilege access without agents, new hardware, or re-IPing.
CybersecurityEnterprise SoftwareIoTSaaSSan Jose, US
Brian Thompson(Executive Officer)inJames Winebrenner(Executive Officer, Director)in
BoardBrian Long(Director)inSpencer Tall(Director)inStephen Ward(Director)in
Board seatMichael Goguen· per SEC Form D
Co-investorsAllegisCyber CapitalAtlantic Bridge VenturesInsight PartnersRain CapitalALLEGIS CAPITAL
BiotechMissoula, US
Brian Conway(Executive Officer)inChristopher Booth(Executive Officer, Director)Sarjubhai Patel(Executive Officer, Director)
Board seatAvery SonnenbergMichael Goguen· per SEC Form D
Novoron develops lipoprotein-receptor small molecule therapies aimed at repairing damage and degeneration of the brain and spinal cord, including treatments for proteinopathies and neuroregeneration following traumatic injury.
BiotechDeep TechHealthtechMedical DevicesSan Diego, US
Travis Stiles(CEO & Co-founder)inShawn Gahr(COO & Co-founder)inDavid Weiner(Executive Chairman)Ryan McMillian(CFO & Financial Strategy)
Board seatMichael Goguen· per SEC Form D
Co-investorsBackstage Capital
PulseData builds patented machine learning and AI predictive analytics models that help healthcare organizations identify chronic diseases earlier and predict disease progression, with a focus on kidney disease and end-stage renal disease.
AI & Machine LearningDigital HealthHealthtechNew York, US
Hai Po Sun(Co-founder)inTeddy Cha(Co-Founder)inHai PoinDean Panovich(Chief Executive Officer)in
BoardDANIELLE WANG(Director)
Board seatMichael Goguen· per SEC Form D
Co-investorsBlue CollectiveMilkbox PartnersRed Dog CapitalAndreessen HorowitzBloomberg BetaTiger Global Management
R2 Semiconductor develops power management semiconductor technology, including envelope tracking for RF power amplifiers and core power management for multi-core application processors and digital SoCs.
Deep TechHardwareIoTSemiconductorsSunnyvale, US
DAVID FISHER(Executive Officer, Director)ANDREW HARTLAND(Executive Officer)
BoardFAHRI DINER(Director)ROBERT SCHWARTZ(Director)BOB PAVEY(Director)RICHARD GOLD(Director)
Board seatMichael Goguen· per SEC Form D · $10M raise · filed Aug 2015
Co-investorsThird Point VenturesSigma Prime Ventures, Llc
TileDB builds a database platform for organizing, cataloging, and analyzing large-scale data across organizations.
AI & Machine LearningBiotechCloud ComputingData & InfrastructureEnterprise SoftwareCambridge, US
Stavros Papadopoulos(Executive Officer, Director)inSamuel Madden(Director)in
BoardAbhishek Sharma(Director)in
Board seatMichael Goguen· per SEC Form D
Co-investorsAlleyCorpBig Pi VenturesIntel CapitalNTT DOCOMO VenturesS VenturesSAV (Scale Asia Ventures)+2 more
Abilita Therapeutics is a drug discovery company focused on membrane protein targets, using its EMP (Enabled Membrane Proteins) technology based on directed evolution to create stability- and expression-enhanced protein variants for discovering and optimizing drug candidates.
BiotechDeep TechSan Diego, US
Mauro Mileni(Founder & Chief Executive Officer)inMatthew Ritter(Chief Business Officer)Jim Schmidt(Chief Financial Officer)Arshan Amiri(General Counsel)
Bain Capital Private Equity is an investment firm operating a private equity portfolio, with an investor portal for account holders.
Boston, US
Co-investorsBain Capital Double Impact Fund LPBain Capital Life SciencesBain Capital Tech OpportunitiesBain Capital Venture
Santa Monica, US
Alex Matrosov(Founder)
Co-investorsCanaan PartnersStoneMill Ventures
Conceal builds browser-based security that moves enforcement into the browser runtime and application layer, binding application access to identity rather than network location.
CybersecurityEnterprise SoftwareSaaSAugusta, US
Craig Whetstone(Executive Officer)inEric Cornelius(Director, Executive Officer)inGordon Lawson(Executive Officer, Director)inRonald Kolson(Executive Officer)
BoardSpencer Tall(Director)inRon Gula(Director)in
Co-investorsAllegisCyber CapitalGula Tech AdventuresRRE Ventures
Dymium is a data-centric, zero-trust platform that governs access to enterprise data in real time, applying identity-, role-, and context-based policies before data is returned.
AI & Machine LearningCybersecurityData & InfrastructureLos Gatos, US
Valentyn Kamyshenko(Founder)in
Co-investorsSINEWAVE VENTURES
Graphiant provides a software-based, unified network platform for connecting AI, cloud, SaaS, B2B, and branch environments.
Cloud ComputingData & InfrastructureEnterprise SoftwareSan Jose, US
Stefan Olofsson(Founder)in
Co-investorsHarpoon VenturesMVP VenturesAtlantic Bridge VenturesIAG Capital PartnersSequoia CapitalWa'ed Ventures
Gravwell is a security data platform that collects, stores, and analyzes unstructured logs and large data volumes in raw format without enforcing predefined schemas.
CybersecurityData & InfrastructureEnterprise Software
Kristopher Watts(Founder)in
Co-investorsGula Tech AdventuresInnosphere VenturesKickstartNext Frontier Capital
Gula Tech Adventures invests in and supports cybersecurity companies, combining venture investments with philanthropy and cyber advocacy.
Cybersecurity
Ron Gula(Co-founder)inCyndi Gula(Co-founder)in
Co-investorsInner Loop CapitalGula Tech Adventures
Leapfrog Bio is an oncology therapeutics company that uses its Precision PGx Platform to identify and develop targeted cancer treatments, focusing on patients with loss-of-function mutations through synthetic lethality and pharmacogenomic screening.
AI & Machine LearningBiotechDeep TechHealthtechMedical Devices
Tomas Babak(Founder and CSO)in
Montara is a biotech company developing small-molecule therapeutics focused on neurodegeneration and diseases such as Alzheimer's.
AI & Machine LearningBiotechDeep TechSan Francisco, US
Kevan Shokat(Co-Scientific Founder & Chairman of the SAB)Thomas Südhof(Co-Scientific Founder & SAB Member)Seth Stratton(Director)Dirk Langdorf(Director)Nicholas Hertz(Executive Officer, Director)
Co-investorsBEVCDolby Family VenturesSV Health InvestorsDementia Discovery FundKdT Ventures
QuSecure provides a cryptographic management platform that discovers, remediates, and reports on encryption across cloud, on-premises, and legacy systems.
Crypto & Web3CybersecurityEnterprise SoftwareQuantum ComputingSan Mateo, US
Rebecca Krauthamer(Founder)inDave Krauthamer(Founder)in
Co-investorsKickstart InnovationTechstarsAccenture VenturesBand of Angels
Rainfall Health provides a compliance and reimbursement-modeling platform built for the CMS TEAM Model, helping hospital CEOs and CFOs quantify and capture TEAM incentives across surgical episodes and the mandatory 30-day post-discharge window.
Digital HealthHealthtechSaaS
Ahmed 'Eddie' Qureshi(Founder)in
Revenium provides real-time attribution and cost monitoring for AI spend, breaking down every model call, agent turn, and tool call by team, customer, feature, and agent.
AI & Machine LearningCloud ComputingData & InfrastructureFintechSaaS
John(Co-founder (Architecture Lead))inJason(Co-founder (Product Strategy))in
Co-investorsWestWave Capital
Selector builds an AI-driven observability platform that helps operations teams understand and manage complex infrastructure through natural language interaction and contextual intelligence.
AI & Machine LearningData & InfrastructureEnterprise SoftwareSanta Clara, US
Kannan Kothandaraman(Founder)inNitin Kumar(Founder)in
Co-investorsAnsa CapitalAtlantic Bridge VenturesAzure Capital PartnersComcast VenturesSINEWAVE VENTURESAtlantic Vantage Point+2 more
Talus develops a proprietary platform that measures and modulates the regulome—the body's gene expression control system—in native cellular contexts.
AI & Machine LearningBiotechDeep TechHealthtechSeattle, US
Alex Federation(Founder)inLindsay Pino(Founder)inAlex Federation, Ph.D.(Chief Executive Officer & Co-Founder)Lindsay Pino, Ph.D.(Chief Technology Officer & Co-Founder)
BoardOmri Amirav-Drory(Director)inJ. Seth Strattan(Director)in
Co-investorsFarvatn VentureFifty YearsFundersClubJude GomilaNFXY Combinator+1 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Portfolio news
latest coverage across their companiesSelector AI · finsmes.com · Feb 18, 2026
Rainfall Health · finsmes.com · Feb 18, 2026
Revenium · prnewswire.com · Nov 20, 2025
Gravwell · fintech.global · Oct 22, 2025
Conceal · fintech.global · Oct 17, 2025
Frequently asked questions
- How many investments has Two Bear Capital made?
- Two Bear Capital has 28 tracked investments, including 7 dated in the last 24 months.
- What stage does Two Bear Capital invest at?
- Two Bear Capital invests at the Pre-Seed, Seed, Series A, Series B stages.
- What is Two Bear Capital's typical check size?
- Two Bear Capital typically writes checks of $3M – $10M.
- What sectors does Two Bear Capital focus on?
- Two Bear Capital focuses on AI & Machine Learning, Biotech, Cybersecurity, Data & Infrastructure, Deep Tech, Digital Health, Healthtech, Longevity.
- Where is Two Bear Capital located?
- Two Bear Capital is headquartered in Whitefish, US.
- Does Two Bear Capital lead rounds?
- Yes, Two Bear Capital leads investment rounds.
- Who does Two Bear Capital co-invest with?
- Two Bear Capital most often shares deals with AllegisCyber Capital, Atlantic Bridge Ventures, Gula Tech Adventures, among 39 tracked co-investors.
Media · Podcasts & interviews
featuring the teamMembers Talk - Mike Goguen - Founder & CEO, Two Bear Capital
FII Institute · Mike Goguen
Hello Whitefish - Cris Neckar - Hacking life / Two Bear Capital (Episode 14)
Hello Whitefish · Cris Neckar
Two Bear Capital: Why Montana, Why Now? Transformational Opportunities in Life Science w Mike Goguen
Montana High Tech Business Alliance · Mike Goguen
Images
Co-investors · 28
Atlantic Bridge is a global growth equity technology firm investing in technology companies across Europe and the US, with multiple funds under management and a dedicated University Bridge Fund for early-stage deeptech.
AllegisCyber Capital is a venture capital firm focused exclusively on cybersecurity investments, emphasizing deep domain expertise and operating experience.
Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.
Sequoia Capital is a venture capital firm that partners with founders to build technology companies.
Insight Partners is an investment firm focused on accelerating revenue and profit growth in software companies, providing capital and operational support through its Insight Onsite team.
Canaan Partners is a venture capital firm with over 30 years of history, backing companies across technology and healthcare sectors through close, hands-on partnerships with founders.
Third Point Ventures is the venture capital arm of Third Point LLC, backing technology founders across the full corporate lifecycle and offering guidance, coaching, and connections.
WestWave Capital is an early-stage venture firm run by former entrepreneurs that backs AI-native and deep-tech founders building enterprise software, investing at inception before consensus.
Greylock Partners is an early-stage venture capital firm that partners with founders building companies from inception. Its partners make only one or two new investments per year to focus deeply on each partnership.
Menlo Ventures is an early-stage venture capital firm backing transformative technology companies, with a strong current emphasis on artificial intelligence across enterprise, healthcare, and consumer markets.
Sapphire Ventures partners with expansion-stage enterprise software companies, aiming to help them become category leaders. Its Platform team of operators supports portfolio companies with customer introductions, go-to-market talent, and growth advisory.
Battery Ventures is a global investment firm that has backed more than 450 companies over its 40-year history, operating its investment staff as a single global unit.
▶16 more co-investors
Liquid VenturesNexus Venture PartnersAccompliceWingUnusual VenturesTenaya CapitalCisco InvestmentsWalden InternationalEvolution Equity PartnersS3 VenturesAcrobator VenturesMorgenthalerDag VenturesLumia CapitalEmerald Technology Ventures AgDigital Horizon VC
Firms observed investing alongside Two Bear Capital, from public investor directories. Shared companies are the overlap with Two Bear Capital's recorded portfolio.
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