/Companies

AcuraStem

Pasadena, US · Founded 2016 · Delaware corporation · 2 known investors

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AcuraStem is a biotechnology company developing antisense oligonucleotide treatments for neurodegenerative diseases such as ALS and frontotemporal dementia, using its iNeuroRx technology platform for disease modeling and drug discovery. It targets PIKFYVE, discovered by its co-founders, to advance a pipeline of therapies.

Founders & leadership

AcuraStem was founded in 2016 by Justin Ichida and Sam Alworth.

JIJustin Ichida
Justin IchidaCo-Founder
SASam Alworth
Sam AlworthCo-founder · Chief Executive OfficerHe has over 20 years of experience in life sciences including research and drug development, and previously led development of AI-enabled drug discovery software that was acquired by Leica.
MVMarcel van der Brug
Marcel van der BrugChief Scientific Officer
RB
Robert BowserChief Scientific Officer

Board

QL
Qing Liu-MichaelBoard director
PA
Paul AugustBoard director

Investors · 2

Reported raises · per SEC filings

Form D private placements

$3.9M disclosed across 3 of 6 rounds · 2018–2026

▶$5MofferedJun 2026 · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Samuel AlworthExecutive Officer, Director
  • Qing Liu-MichaelDirector
  • Paul AugustDirector
  • Marcel van der BrugExecutive Officer
  • Justin IchidaDirector
Offering amount
$5M
Minimum investment
$10K
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$3.1MraisedNov 2022 · 1 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Justin IchidaDirector
  • Samuel AlworthExecutive Officer, Director
  • Paul AugustDirector
  • Qing Liu-MichaelDirector
Offering amount
$3.1M
Amount sold
$3.1M
Minimum investment
$25K
First sale
Nov 2022
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$400KraisedNov 2022 · 1 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Paul AugustDirector
  • Justin IchidaDirector
  • Samuel AlworthExecutive Officer, Director
  • Qing Liu-MichaelDirector
Offering amount
$3.5M
Amount sold
$400K
Minimum investment
$25K
First sale
Nov 2022
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$380KraisedJun 2019 · 1 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Samuel AlworthExecutive Officer, Director
  • Paul AugustDirector
  • Justin IchidaExecutive Officer, Director
  • Qing Liu-MichaelDirector
Offering amount
$2M
Amount sold
$380K
Minimum investment
$25K
Proceeds to insiders
$150K
First sale
Jun 2018
Incorporated
Corporation, Delaware, 2016
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Related companies · 4

Companies working in the same space as AcuraStem.

Non-dilutive funding · 6 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
National Institutes of Health (NIH)National Institutes of HealthPhase II2023$1.5M
National Institutes of Health (NIH)National Institutes of HealthPhase II2023$1.4M
National Institutes of Health (NIH)National Institutes of HealthPhase II2021$2.6M
National Institutes of Health (NIH)National Institutes of HealthPhase II2019$3M
National Institutes of Health (NIH)National Institutes of HealthPhase I2018$433.1K
National Institutes of Health (NIH)National Institutes of HealthPhase I2017$224.9K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

In the news

Frequently asked questions

What does AcuraStem do?
AcuraStem is a biotechnology company developing antisense oligonucleotide treatments for neurodegenerative diseases such as ALS and frontotemporal dementia, using its iNeuroRx technology platform for disease modeling and drug discovery. It targets PIKFYVE, discovered by its co-founders, to advance a pipeline of therapies.
Who founded AcuraStem?
AcuraStem was founded by Justin Ichida, Sam Alworth in 2016.
Who are AcuraStem's investors?
AcuraStem's investors include CANTILEVER INVESTORS, Keiretsu Forum.
How much funding has AcuraStem raised?
AcuraStem has disclosed $3.9M raised across 3 of its 6 known rounds.
Where is AcuraStem headquartered?
AcuraStem is headquartered in Pasadena, US.