/Companies

Allyx Therapeutics, Inc.

New Haven, US · Founded 2018 · Delaware corporation · 5 employees on LinkedIn · 4 known investors

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Allyx Therapeutics is a clinical-stage biopharmaceutical company developing therapies to preserve and protect synapses in people with neurodegenerative diseases. Its lead compound, ALX-001, is a first-in-class oral therapy acting at mGluR5, currently in Phase 1b clinical development for Alzheimer's disease.

Founders & leadership

Allyx Therapeutics, Inc. was founded in 2018 by Paul Fonteyne, Stephen Strittmatter, Stephen Bloch, Timothy Siegert, and Tim Siegert, PhD.

PFPaul Fonteyne
Paul FonteyneCo-FounderInvestor at Canaan Partners
SSStephen Strittmatter
Stephen StrittmatterScientific Founder
SBStephen Bloch
Stephen BlochCEO & Co-FounderStephen Bloch is CEO and co-founder of Allyx Therapeutics. He previously spent over 23 years as a General Partner at Canaan Partners investing in healthcare companies, served as CEO of RMS (a radiology benefits management company) for 6 years, and worked as a pharmaceutical strategy consultant at Arthur D. Little.
TSTimothy Siegert
Timothy SiegertCo-founder · Chief Operating Officer
TS
Tim Siegert, PhDCOO & Co-Founder
JGJennifer Gabler
Jennifer GablerFinance ConsultantJennifer Gabler serves as an Executive Officer at Allyx Therapeutics. She previously held CFO positions at multiple venture-backed and biotech companies and co-founded Marlborough Street Partners, which provides strategic and operational services to investors and venture-funded enterprises.

Board

RARobert A. Bettigole
Robert A. BettigoleBoard MemberManaging Partner at Elm Street Ventures
GP
Gregory P. HoBoard directorGeneral Partner at WHIN

Investors · 4

Reported raises · per SEC filings

Form D private placements

$39.6M disclosed across 4 rounds · 2021–2026

▶$26.4MraisedMay 2026 · 32 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Stephen BlochExecutive Officer, Director
  • Stephen StrittmatterDirector
  • Robert A BettigoleDirector
  • Paul FonteyneDirector
  • Gregory P HoDirector
  • Timothy SiegertExecutive Officer
  • Kevin L. RakinDirector
Offering amount
$30M
Amount sold
$26.4M
Finders' fees
$149.4K
Placement agents
Supervision Partners LLC
First sale
May 2026
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$3.3MraisedMar 2026 · 12 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Jennifer GablerExecutive Officer
  • Robert A BettigoleDirector
  • Paul FonteyneDirector
  • Gregory P HoDirector
  • Stephen StrittmatterDirector
  • Stephen BlochExecutive Officer, Director
  • Timothy SiegertExecutive Officer
Offering amount
$4M
Amount sold
$3.3M
First sale
Feb 2026
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$2.3MraisedFeb 2023 · 11 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Robert A. BettigoleDirector
  • Stephen StrittmatterDirector
  • Paul FonteyneDirector
  • Gregory P. HoDirector
  • Timothy SiegertExecutive Officer
  • Stephen BlochExecutive Officer, Director
Offering amount
$2.3M
Amount sold
$2.3M
First sale
Feb 2023
Incorporated
Corporation, Delaware, 2018
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$7.6MraisedJun 2021 · 10 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Gregory P. HoDirector
  • Robert A. BettigoleDirector
  • Stephen StrittmatterExecutive Officer, Director
  • Stephen BlochExecutive Officer, Director
  • Timothy SiegertExecutive Officer
  • Paul FonteyneDirector
Offering amount
$8M
Amount sold
$7.6M
First sale
May 2021
Incorporated
Corporation, Delaware, 2018
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Founder mafia

2 people who came through Allyx Therapeutics, Inc. went on to found or lead other companies.

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Companies working in the same space as Allyx Therapeutics, Inc..

Non-dilutive funding · 2 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
National Institutes of Health (NIH)National Institutes of HealthPhase II2022$2M
National Institutes of Health (NIH)National Institutes of HealthPhase I2020$450K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

Frequently asked questions

What does Allyx Therapeutics, Inc. do?
Allyx Therapeutics is a clinical-stage biopharmaceutical company developing therapies to preserve and protect synapses in people with neurodegenerative diseases. Its lead compound, ALX-001, is a first-in-class oral therapy acting at mGluR5, currently in Phase 1b clinical development for Alzheimer's disease.
Who founded Allyx Therapeutics, Inc.?
Allyx Therapeutics, Inc. was founded by Paul Fonteyne, Stephen Strittmatter, Stephen Bloch, Timothy Siegert, Tim Siegert, PhD in 2018.
Who are Allyx Therapeutics, Inc.'s investors?
Allyx Therapeutics, Inc.'s investors include Elm Street Ventures, Spring Mountain Capital, Connecticut Innovations, WHIN.
How much funding has Allyx Therapeutics, Inc. raised?
Allyx Therapeutics, Inc. has disclosed $39.6M raised across 4 rounds.
Where is Allyx Therapeutics, Inc. headquartered?
Allyx Therapeutics, Inc. is headquartered in New Haven, US.