/Companies

Nephrogen

YC S20Techstars '25

New York City, US · Founded 2022 · 5 employees · 21 known investors

Find your way into Nephrogen

Sign up to see every warm intro you have to Nephrogen

  • Paths you didn't know you had: your email and LinkedIn already hold routes to the Nephrogen team. We find them for you
  • 2nd- and 3rd-degree connections: the friend-of-a-friend routes that take hours to manually find through your inbox or LinkedIn
  • Answers now, not in days: momentum is everything in a raise. Skip asking around whether someone knows someone

Days of research, done the moment you sign in, with every route ranked by how warm it is.

Nephrogen develops AI-powered AAV delivery vehicles for genetic medicines targeting kidney and pancreatic diseases. The company uses high-throughput in vivo screening to design tissue-specific viral vectors that are significantly more efficient and less immunogenic than existing alternatives.

Founders & leadership· Y Combinator alumni (S20)

Nephrogen was founded in 2022 by Demetri Maxim and Demetri M..

DMDemetri Maxim
Demetri MaximFounder and CEO
DM
Demetri M.Founder
VBVivek Bhalla
Vivek BhallaChief Medical Officer

Investors · 21

Techstarslisted by TechstarsBoulder · $220K

How we know: the Techstars portfolio · open dataset · 5k.vc investor directory · Y Combinator's founder network · Not right? Tell us

Y Combinatorlisted by Y CombinatorSan Francisco · $500K

How we know: the Y Combinator directory · Y Combinator's founder network · Not right? Tell us

ZAKA VClisted by ZAKA VCSan Francisco

How we know: press coverage · Y Combinator's founder network · Not right? Tell us

10X CapitalreportedNew York

How we know: Y Combinator's founder network · Not right? Tell us

2048 VenturesreportedNew York · $500K – $3M

How we know: Y Combinator's founder network · Not right? Tell us

Agrolimen Venturesreported

How we know: Y Combinator's founder network · Not right? Tell us

ContraryreportedSan Francisco · $2M

How we know: Y Combinator's founder network · Not right? Tell us

Duke Capital PartnersreportedDurham

How we know: Y Combinator's founder network · Not right? Tell us

Milkbox PartnersreportedNew York

How we know: Y Combinator's founder network · Not right? Tell us

National Kidney Foundation, Inc.reportedNew York

How we know: Y Combinator's founder network · Not right? Tell us

Phoenix FundreportedNew York

How we know: Y Combinator's founder network · Not right? Tell us

Pillar VCreportedBoston · $50K – $4M

How we know: Y Combinator's founder network · Not right? Tell us

Shorewind CapitalreportedSan Francisco

How we know: Y Combinator's founder network · Not right? Tell us

Sparkwave Capitalreported

How we know: Y Combinator's founder network · Not right? Tell us

TK Venturesreported

How we know: Y Combinator's founder network · Not right? Tell us

Related companies · 8

Uncommon TherapeuticsUncommon Therapeutics uses advanced technologies to develop drugs targeting rare genetic diseases, starting with Rett Syndrome, a neurodevelopmental disorder affecting approximately 1 in 10,000 girls. The company combines disease expertise with efficient drug development to advance therapeutics from discovery to clinical application.
Algen BiotechnologiesAlgen Biotechnologies discovers and develops small molecule therapeutics for cancer and inflammatory diseases using CRISPR, RNAi, and machine learning to decode functional gene networks and predict drug responses.
Biogen IdecBiogen is a biotechnology company founded in 1978 that focuses on breakthroughs in biology. The company serves patients through research and development in the life sciences industry.
LEAH LabsLEAH Labs engineers gene-edited CAR-T cell therapies to treat cancer in pet dogs, with the goal of generating translational insights for human cancer therapy. The company uses proprietary gene editing and protein design to develop therapeutic treatments for companion animal oncology.
BioworldBioWorld is a suite of daily news and data services covering therapeutics, medical technology, biopharma business transactions, and drug R&D, serving biopharmaceutical and medtech industry professionals. Owned by Clarivate, it publishes products including BioWorld, BioWorld Science, and BioWorld Asia with reporting from writers stationed globally.
Kopra BioKopra Bio develops cancer immunotherapy technology that converts cancer cells into biofactories to produce their own destruction. The company operates in the biotech and cancer treatment space.
PepGenPepGen is a clinical-stage biotech company developing oligonucleotide therapies for neuromuscular and neurological diseases using its Enhanced Delivery Oligonucleotide (EDO) platform to improve tissue penetration and uptake in muscle tissues.
PrecigenPrecigen is a biopharmaceutical company developing gene and cell therapies, including PAPZIMEOS (zopapogene imadenovec-drba), an FDA-approved immunotherapy for adults with recurrent respiratory papillomatosis. The company focuses on immuno-oncology and immunotherapy treatments delivered via subcutaneous injection.

Companies working in the same space as Nephrogen.

Non-dilutive funding · 1 SBIR/STTR award

Federal grants — no equity taken
AgencyPhaseYearAmount
National Institutes of Health (NIH)National Institutes of HealthPhase ISTTR2023$325K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

Legal entities · 1

corporate structure
Nephrogen Inc.

Frequently asked questions

What does Nephrogen do?
Nephrogen develops AI-powered AAV delivery vehicles for genetic medicines targeting kidney and pancreatic diseases. The company uses high-throughput in vivo screening to design tissue-specific viral vectors that are significantly more efficient and less immunogenic than existing alternatives.
Who founded Nephrogen?
Nephrogen was founded by Demetri Maxim, Demetri M. in 2022.
Who are Nephrogen's investors?
Nephrogen's investors include Chicago Early Growth Ventures (CEGV), Gaingels, Novogenia GmbH, StartX, Techstars, Y Combinator, ZAKA VC, 10X Capital and 13 more.
Where is Nephrogen headquartered?
Nephrogen is headquartered in New York City, US.