/Investor DB

ALS Investment Fund

Venture capital

Amsterdam · Seed · 9 people tracked

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Investment thesis

ALS Investment Fund backs biotech companies developing therapies for neurodegeneration, with a special emphasis on ALS. The firm highlights that neurodegeneration is a leading cause of death and disability, affecting roughly one in five people, with ALS affecting about one in 350. It believes new drugs could meaningfully improve quality of life within the next decade by preserving cognition and motor function, potentially turning neurodegenerative diseases into managed conditions. Having operated for about ten years, the fund supports people and companies working to change the trajectory of these diseases and accelerate a new generation of treatments.

Source: firm website, verified Oct 3, 2026.

Stage
Seed
HQ
Amsterdam, NL
Instruments
Equity
Tracked investments
11
Unicorns
1
IPOs
2

Team · 9 people

from the firm's website & public directories
Jeroen van der Pol· Chief Financial Officerin
Nancy de Ruiter· Chair Advisory Committeein
Olivier Tak· Science & DDin
Rist Brouwer· Advisor Investment Committeein
Siya Chandrie· Investor Relationsin

What they invest in

from 10 of 11 portfolio companies

Biotech ×10Deep Tech ×5Healthtech ×5Medical Devices ×4Digital Health ×2AI & Machine Learning ×1

HQs:United States×8Netherlands×1

Investments · 11 tracked

founders shown can be your intro path

By year:2023 · 12021 · 34 dated

Amylyxamylyx.comin𝕏NASDAQ: AMLX

Amylyx is a biopharmaceutical company developing novel therapies for diseases with high unmet medical needs.

BiotechHealthtechCambridge, US

Justin Klee(Director)inJoshua Cohen(Founder)in

BoardStephen D. Chubb(Director)George M. Milne, PH.D.(Director)

Co-investorsAlpha Wave GlobalAvoro Capital AdvisorsBain Capital Life Sciences

Kempharmkempharm.comNASDAQ: ZVRA

BiotechCoralville, US

Travis C. Mickle(Executive Officer, Director, Promoter)Christal M.M. Mickle(Executive Officer, Director)Gordon K. Johnson(Executive Officer)Tracy M. Woody(Executive Officer)Sven Guenther(Executive Officer, Director)Neil F. McFarlane(President, Chief Executive Officer and Director)

Bloom Sciencebloomscience.comin𝕏Series A · Dec 2021 · $12M

Bloom Science is a clinical-stage biotech company developing live biotherapeutic products that replicate the effects of the ketogenic diet through the gut-brain axis.

BiotechDeep TechDigital HealthSan Diego, US

Co-investorsJoyance PartnersPsyMed VenturesSocial StartsApollo Health VenturesLeaps by Bayer

Emulate Bioemulatebio.comin𝕏

Emulate builds Organ-on-a-Chip systems, including platforms, consumables, and pre-assembled BioKits with validated human cell models, to support drug discovery research.

BiotechDeep TechHealthtech

Donald Ingber(Founder)inDaniel Levner(Co-Founder & CTO)inJim Corbett(CEO, Board Member)inLorna Ewart(Chief Scientific Officer)in

Co-investors+ND CapitalNorthpond VenturesAlumni VenturesAlwyn CapitalFourth RealmStray Dog Capital+4 more

Prileniaprilenia.com

Prilenia is a biotechnology company developing treatments for neurodegenerative diseases, including Huntington's disease and amyotrophic lateral sclerosis (ALS).

BiotechHealthtechMedical Devices

Co-investorsSV Health InvestorsAmplitude Venture CapitalForbion

ProJenXprojenx.comin𝕏Dec 2021

ProJenX is a clinical-stage biotechnology company developing novel, brain-penetrant therapies for neurodegenerative diseases, with an initial focus on amyotrophic lateral sclerosis (ALS).

BiotechDeep TechMedical DevicesNissequogue, US

Valerie Estess(Director)

BoardJohn Prufeta(Director)inEric Heil(Director)inJoni Mancini(Executive Officer)inBrent R. Stockwell(Chair of the Department of Biological Science, Professor at Columbia University)Hynek Wichterle(Jerry and Emily Spiegel Professor at Columbia University)

Co-investorsMedical Excellence Capital

Quralisquralis.comin𝕏Mar 2023

QurAlis develops precision therapies for amyotrophic lateral sclerosis (ALS) and related neurodegenerative diseases by targeting specific disease-causing genetic drivers and molecular mechanisms.

BiotechDeep TechMedical DevicesCambridge, US

Kevin Eggan(Founder, QurAlis; Group Vice President, Head of Research and Early Development, BioMarin Pharmaceutical)inRoet(Co-founder)Woolf(Co-founder)Kasper Roet(Founder, Chief Executive Officer)inShafique Virani(Executive Officer)inJason Brown(Mr. Brown is the Chief Financial Officer of the Issuer.)in

Co-investorsDolby Family VenturesDroia VenturesInkefMC Healthcare VenturesMission BiocapitalMitsui Global Investment+8 more

Uniqureuniqure.comin𝕏

uniQure is a biotech company developing gene therapies for serious genetic diseases.

BiotechHealthtechMedical Devices

Matthew Kapustain

Co-investorsAdvent Life SciencesForesite CapitalHEALTHCARE ROYALTY PARTNERSRidgeback CapitalForbion

Verge Genomicsvergegenomics.comin𝕏Series A

Verge Labs builds AI models trained on multimodal human patient data to predict drug targets and patient populations for clinical development, primarily in neuroscience and central nervous system (CNS) disease.

AI & Machine LearningBiotechDeep TechDigital HealthHealthtechSan Francisco, US

Alice Zhang(CEO)inJason Chen(Founder)inEmily Ripka(Vice President Product \u0026 Engineering)inNaveen Jain(Investor)inGeorge Spencer(Operations)

Co-investorsAgent CapitalBOLD LongevityDraper AssociatesFitz Gate VenturesGreat Oaks Venture CapitalKarlin Ventures+28 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Apic BioVectory

Exits · 2

2 IPOs

AmylyxNASDAQ: AMLXKempharmNASDAQ: ZVRA

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has ALS Investment Fund made?
ALS Investment Fund has 11 tracked investments, 2 of which have exited.
What stage does ALS Investment Fund invest at?
ALS Investment Fund invests at the Seed stage.
What sectors does ALS Investment Fund focus on?
ALS Investment Fund focuses on Biotech, Healthtech.
Where is ALS Investment Fund located?
ALS Investment Fund is headquartered in Amsterdam, NL.
Who does ALS Investment Fund co-invest with?
ALS Investment Fund most often shares deals with SV Health Investors, Draper Associates, Medical Excellence Capital, among 38 tracked co-investors.

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