ALS Investment Fund
Venture capitalAmsterdam · Seed · 9 people tracked
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Investment thesis
ALS Investment Fund backs biotech companies developing therapies for neurodegeneration, with a special emphasis on ALS. The firm highlights that neurodegeneration is a leading cause of death and disability, affecting roughly one in five people, with ALS affecting about one in 350. It believes new drugs could meaningfully improve quality of life within the next decade by preserving cognition and motor function, potentially turning neurodegenerative diseases into managed conditions. Having operated for about ten years, the fund supports people and companies working to change the trajectory of these diseases and accelerate a new generation of treatments.
Source: firm website, verified Oct 2, 2026.
Team · 9 people
from the firm's website & public directoriesWhat they invest in
from 8 of 11 portfolio companiesBiotech ×8Deep Tech ×5Healthtech ×4Medical Devices ×3Digital Health ×2AI & Machine Learning ×1
HQs:United States×7Netherlands×1
Investments · 11 tracked
founders shown can be your intro pathBy year:2023 · 12021 · 23 dated
Amylyx is a biopharmaceutical company developing novel therapies for diseases with high unmet medical needs.
BiotechHealthtechCambridge, US
Justin Klee(Director)inJoshua Cohen(Founder)in
BoardStephen D. Chubb(Director)George M. Milne, PH.D.(Director)
Co-investorsAlpha Wave GlobalAvoro Capital AdvisorsBain Capital Life Sciences
Bloom Science is a clinical-stage biotech company developing live biotherapeutic products that replicate the effects of the ketogenic diet through the gut-brain axis.
BiotechDeep TechDigital HealthSan Diego, US
Co-investorsJoyance PartnersPsyMed VenturesSocial StartsApollo Health VenturesLeaps by Bayer
Emulate builds Organ-on-a-Chip systems, including platforms, consumables, and pre-assembled BioKits with validated human cell models, to support drug discovery research.
BiotechDeep TechHealthtech
Donald Ingber(Scientific Founder, Board Member, Scientific Advisory Board Chairman)inDaniel Levner(Co-Founder & CTO)inJim Corbett(CEO, Board Member)inLorna Ewart(Chief Scientific Officer)in
Co-investors+ND CapitalNorthpond VenturesAlumni VenturesAlwyn CapitalFourth RealmStray Dog Capital+3 more
ProJenX is a clinical-stage biotechnology company developing novel, brain-penetrant therapies for neurodegenerative diseases, with an initial focus on amyotrophic lateral sclerosis (ALS).
BiotechDeep TechMedical DevicesNissequogue, US
Valerie Estess(Director)
BoardJohn Prufeta(Director)inEric Heil(Director)inJoni Mancini(Executive Officer)inBrent R. Stockwell(Chair of the Department of Biological Science, Professor at Columbia University)Hynek Wichterle(Jerry and Emily Spiegel Professor at Columbia University)
Co-investorsMedical Excellence Capital
QurAlis develops precision therapies for amyotrophic lateral sclerosis (ALS) and related neurodegenerative diseases by targeting specific disease-causing genetic drivers and molecular mechanisms.
BiotechDeep TechMedical DevicesCambridge, US
Kevin Eggan(Co-founder)inRoet(Co-founder)Woolf(Co-founder)Kasper Roet(Director, Executive Officer, Promoter)inShafique Virani(Executive Officer)inJason Brown(Mr. Brown is the Chief Financial Officer of the Issuer.)in
Co-investorsDolby Family VenturesDroia VenturesInkefMC Healthcare VenturesMission BiocapitalMitsui Global Investment+8 more
uniQure is a biotech company developing gene therapies for serious genetic diseases.
BiotechHealthtechMedical Devices
Co-investorsAdvent Life SciencesForesite CapitalHEALTHCARE ROYALTY PARTNERSRidgeback Capital
Verge Labs builds AI models trained on multimodal human patient data to predict drug targets and patient populations for clinical development, primarily in neuroscience and central nervous system (CNS) disease.
AI & Machine LearningBiotechDeep TechDigital HealthHealthtechSan Francisco, US
Alice Zhang(Co-founder & CEO)inJason Chen(Cofounder)inEmily Ripka(Head of Product & Engineering)in
Co-investorsAgent CapitalBOLD LongevityDraper AssociatesFitz Gate VenturesGreat Oaks Venture CapitalKarlin Ventures+28 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Apic BioVectory
Exits · 1
1 IPOsAmylyxNASDAQ: AMLX
Frequently asked questions
- How many investments has ALS Investment Fund made?
- ALS Investment Fund has 11 tracked investments, 1 of which have exited.
- What stage does ALS Investment Fund invest at?
- ALS Investment Fund invests at the Seed stage.
- What sectors does ALS Investment Fund focus on?
- ALS Investment Fund focuses on Biotech, Healthtech.
- Where is ALS Investment Fund located?
- ALS Investment Fund is headquartered in Amsterdam, NL.











































