SV Health Investors — Full Portfolio

Alector develops therapies targeting neurodegenerative diseases including Alzheimer's, frontotemporal dementia, and Parkinson's disease through protein removal, replacement, and immune cell restoration.

AI & Machine LearningBiotechHealthtechLongevityMedical DevicesSan Francisco, US

ARArnon Rosenthal(Ph.D.)inTGTillman Gerngross(Director)

BoardCarl Gordon(Director)TMTerry McGuire(Director)in

Co-investorsFOForesite CapitalGVGV (Google Ventures)MIMission Bay CapitalMIMission BiocapitalMRMRL Ventures FundPOPolaris Partners

American Well operates a digital healthcare platform that connects patients, physicians, and healthcare professionals to provide remote clinical services, earning revenue through arrangements with healthcare organizations and clients who use its technology to deliver telehealth and related services.

HealthtechBoston, US

ISIdo Schoenberg(Executive Officer, Director)inRSRoy Schoenberg(Executive Officer, Director)inJames Malone(Executive Officer)inBradford F. Gay(Executive Officer)PGPhyllis Gotlib(President, International)inMHMark Hirschhorn(Executive Vice President, Chief Financial Officer and Chief Operating Officer)in

Co-investorsHAHanaco Venture CapitalMAMartin VenturesSVSV Life Sciences

Bicycle Therapeutics develops precision-guided therapeutics based on its proprietary bicyclic peptide (Bicycle) technology, designed to penetrate deep into tissues and target intractable solid tumor cancers.

BiotechHealthtechCambridge, GB

GWGregory Winter(Director)inNCNIGEL CROCKETT(Executive Officer)inNKNICHOLAS KEEN(Executive Officer)SASANTIAGO ARROYO(Executive Officer)inMICHAEL HANNAY(Executive Officer)MICHAEL SKYNNER(Executive Officer)in

Co-investorsAHAhren Innovation CapitalASAstellas Venture Management LLCCACambridge Innovation CapitalDEDementia Discovery FundLOLongwood FundRIRidgeback Capital+4 more

BIOAGE develops therapies targeting the molecular pathways that drive aging to increase healthspan and address age-related chronic diseases.

BiotechHealthtechLongevityRichmond, US

KFKristen Fortney, PhD(Co-Founder, CEO)EMEric Morgen, MD(Co-Founder, COO)KFKristen Fortney(Founder)inEMEric Morgen(Founder)inDGDov Goldstein(Executive Officer)in

BoardPEPatrick Enright(Director)in

Co-investorsANAndreessen HorowitzELElad GilFEFelicis VenturesGRGreen Sands EquityIAIA Seed VenturesLOLongitude Capital+19 more

Insulet develops the Omnipod, a tubeless, wearable, disposable insulin delivery Pod, along with automated insulin delivery systems for people managing insulin-dependent diabetes.

Digital HealthHardwareHealthtechMedical DevicesActon, US

AAAshley A. McEvoy(Director, President and Chief Executive Officer)inFPFlavia Pease(Executive Vice President and Chief Financial Officer)inEBEric Benjamin(Executive Vice President, Chief Operating Officer)inLisa Blair Davis(Senior Vice President, Chief Human Resources Officer)inMichael H. Panos(Executive Vice President, Chief Commercial Officer)

Co-investorsWIWinklevoss Capital

Pulse Biosciences develops and commercializes ablation systems based on nanosecond pulsed-field ablation technology to treat medical conditions including benign skin lesions, soft tissue tumors, and cardiac arrhythmias.

BiotechBurlingame, US

Brian B. Dow(Executive Officer)Darrin R. Uecker(Executive Officer, Director)Amy Wang(Executive Officer, Director)Paul A. LaViolette(President and Chief Executive Officer)

BoardMaky Zanganeh(Director)Christopher Marlett(Director)

Sutro is a biotech company developing a cell-free protein synthesis platform for the design and manufacturing of complex biologics, particularly cancer therapies and antibody-drug conjugates.

BiotechDeep TechHealthtechMedical DevicesSouth San Francisco, US

William J. Newell(Executive Officer, Director)JCJane Chung(Chief Executive Officer)inHGHans-Peter Gerber(Chief Scientific Officer)inDPDavid Pauling(Chief Administrative Officer and General Counsel)inJFJonathan Fawcett(VP, Head of Clinical Development)inDevendra Luhar(SVP, Technical Operations)in

Co-investorsOWOwl CapitalRIRidgeback CapitalSASamsara BioCapitalSOSolasta VenturesVIVida Ventures

Xilio Therapeutics is a clinical-stage biotechnology company developing masked immuno-oncology therapies that use protein engineering to remain inactive until activated by tumor-specific proteases within the tumor microenvironment.

BiotechHealthtechWaltham, US

RRRené Russo(Executive Officer, Director)inJoseph Farmer(Executive Officer)Timothy Clackson(Executive Officer)Christopher Frankenfield(Chief Financial and Operating Officer)inKLKatarina Luptakova(Chief Medical Officer)inPaul Clancy(Director)

Co-investorsBABain Capital Life SciencesBABay City CapitalF-F-Prime CapitalM M VenturesMRMRL Ventures FundRARA Capital+9 more

SpectraWAVE develops optical and computational imaging technologies to diagnose and guide treatment decisions for patients with coronary artery disease and cardiovascular disease.

AI & Machine LearningDeep TechHealthtechMedical DevicesBedford, US

ENEman Namati(President & CEO)inGTGuillermo Tearney(Founder; Professor of Pathology, Massachusetts General Hospital)GSGregg Stone(Founder; Professor of Medicine, Mount Sinai Heart Health System)JMJames Muller(Founder; Cardiologist, Brigham and Women's Hospital)inJeffrey O'Donnell(Founder; Managing General Partner, Runway Healthcare)VWVivek Walimbe(Chief Operating Officer)in

Board seatPLPaul LaViolette· per SEC Form D

Co-investorsLULumira VenturesS3S3 VenturesDEDeerfield Management CompanyJOJohnson & Johnson Innovation – JJDC

Alchemab operates a platform that identifies novel drug targets and therapeutics by analyzing patient antibody repertoires using deep B cell sequencing and computational analysis of samples from disease-resilient individuals.

AI & Machine LearningBiotechDeep TechHealthtech

JOJane Osbourn(Founder)Young Kwon(Founder)

Co-investorsRARA CapitalDCDCVC BioDEDementia Discovery FundLILightstone VenturesONOno Venture Investment, Inc.BRBritish Business Bank+3 more

Draig develops neuropsychiatric therapies targeting glutamate and GABA pathways through AMPA and GABAA receptor modulators, serving patients with neuropsychiatric disorders.

BiotechDeep TechDigital HealthMedical DevicesCardiff, GB

John Atack(Head of Biology & Founder)inSWSimon Ward(Chief Scientific Officer & Founder)in

PartnerCDCharles Dunn· led

Co-investorsACAccess BiotechnologyCACanaan PartnersSASanofi VenturesSRSR One Capital ManagementBRBritish Business BankJAJanus Henderson Investors

Dualitas Therapeutics develops bispecific antibody therapies that pair a proprietary proximity engager arm with an antibody against a therapeutic target, using its DualScreen discovery engine to identify synergistic target combinations.

BiotechDeep TechSouth San Francisco, US

Greg Lazar, Ph.D.(Co-Founder and Chief Scientific Officer)FHForbes Huang(Co-Founder, Chief Operating Officer & Chief Business Officer)inGLGreg Lazar(Co-Founder & Chief Scientific Officer)inRichard Murray(Executive Officer, Director)KDKarim Dabbagh(Chief Executive Officer, Board Member)in

BoardALAlicia Levey(Director)

Co-investorsQIQiming Venture PartnersVEVersant VenturesALAlexandriaDEDementia Discovery FundQIQiming HealthcareQIQiming Venture Partners USA

EBT Medical develops neuromodulation technologies targeting the Saphenous nerve to treat pelvic health disorders, particularly overactive bladder.

BiotechMedical Devices

PYPaul Yoo(Co-founder, President & Chief Scientific Officer)inSJSasha John(Co-founder and Chief Innovation Officer)inKRKeith R Carlton(Chief Executive Officer)in

Co-investorsGEGenesys CapitalTOToronto Innovation Acceleration Partners

Enara Bio discovers and validates Dark Antigens from non-coding genomic regions to identify novel cancer targets, and develops first-in-class bispecific T-cell engagers against these targets through its EnTiCE platform.

BiotechDeep TechMedical Devices

George Kassiotis(Co-founder)Drew Pardoll(Co-founder)HAHouman Ashrafian(Co-founder)in

Co-investorsRARA CapitalSASamsara BioCapitalPFPfizer VenturesDEDementia Discovery FundM M VenturesPFPfizer Venture Investments

Harness Therapeutics develops disease-modifying precision therapies for hard-to-treat neurodegenerative diseases through controlled modulation of CNS targets.

BiotechHealthtech

JTJan Thirkettle(CEO Director)in

Co-investorsEPEpidarex CapitalONOno Venture Investment, Inc.DEDementia Discovery Fund

Mestag is an immunology company developing first-in-class treatments for cancer and inflammatory diseases by leveraging novel understanding of fibroblast biology and tertiary lymphoid structures.

AI & Machine LearningBiotechDigital HealthHealthtechLondon, GB

Michael B. Brenner(Founder)Chris Buckley(Founder)MCMark Coles(Founder)inSRSoumya Raychaudhuri(Founder)DADavid A. Tuveson(Founder)Lindsey Rolfe(Chief Medical Officer)in

Co-investorsGVGV (Google Ventures)FOForbionJOJohnson & Johnson Innovation – JJDCNONorthpond VenturesJJJJDC

NRG Therapeutics is a biotech company developing small-molecule drugs targeting the mitochondrial permeability transition pore (mPTP) for neurodegenerative diseases such as ALS and Parkinson's.

BiotechHealthtechLongevity

NMNeil Miller(CEO)inRichard Rutter(CSO)inGrant Hawthorne(COO)inCSClaus Sundgreen(Chief Medical Officer)inPTPaul Thompson(CDO)in

BoardJonathan Savidge(Independent Non Executive Chair)

Co-investorsCRCriteria Bio VenturesNONovartis Venture FundBRBritish Business BankM M VenturesDEDementia Discovery FundOMOmega Funds

Packaging Compliance Labs is an industry leader providing sterile packaging solutions, design validation, and contract packaging services for medical device and life sciences manufacturers.

Advanced ManufacturingEnterprise SoftwareMedical DevicesSaaSGrand Rapids, US

MLMatthew Lapham(CEO & Co-Founder)in

Sitryx is a biotechnology company, founded in 2018, developing therapeutics with a focus on immunometabolism.

BiotechDeep TechHealthtech

Co-investorsLOLongwood FundOXOxford Science EnterprisesSOSofinnova PartnersDEDementia Discovery Fund

Therini Bio is a biotechnology company developing fibrin-targeting therapeutics to treat neurological and ophthalmological diseases, leveraging scientific discoveries in neurovascular and neuroimmune mechanisms of disease.

BiotechDigital HealthHealthtechMedical DevicesSacramento, US

KAKaterina Akassoglou(Scientific Founder, Director of the Center for Neurovascular Brain Immunology and Professor of Neurology at UCSF and Gladstone Institutes)inKAKaterina Akassoglou, PhD(Scientific Founder)LSLeslie Schulze(Executive Officer)TNTara Nickerson(Executive Officer, Director)in

BoardODOlga Danilchanka(Director)inLaia Crespo-Martin(Director)

Co-investorsMRMRL Ventures FundSASanofi VenturesANAngelini VenturesDEDementia Discovery FundDODolby Family VenturesMIMitsui Global Investment+2 more

TRIMTech Therapeutics is a biotechnology company focused on drug discovery and development, backed by investors including Cambridge Innovation Capital and BGF.

BiotechDeep TechLongevityMedical DevicesCambridge, GB

Damian Crowther, PhD FRCP(Co-founder, Head of Research)Dr. Leo James(Co-founder, Group Leader at MRC Laboratory of Molecular Biology)Dr. William McEwan(Co-founder, Group Leader at UK Dementia Research Institute, University of Cambridge)Nicki Thompson, PhD(CEO)Nicki Thompson(CEO)

Co-investorsCACambridge Innovation CapitalPFPfizer VenturesM M VenturesPFPfizer Venture InvestmentsSTStart CodonDIDiamond Edge Ventures

Axon Therapies develops the SAVM procedure, an implant-free catheter-based ablation therapy that targets the right greater splanchnic nerve to reduce overactive sympathetic nerve activity in patients with heart failure with preserved ejection fraction (HFpEF).

HealthtechMedical DevicesNew York, US

HRHoward R. Levin(Executive Officer, Director)Mark Gelfand(Executive Officer)

Board seatPLPaul LaViolette· per SEC Form D · $2M raise · filed Apr 2016

Co-investorsSTStar51 CapitalACAction Potential Venture Capital Ltd.DEDeerfield Management CompanyEAEarlybird Venture Capital

BardyDx develops the Carnation Ambulatory Monitor (CAM), a lightweight cardiac patch monitor designed for extended-wear ambulatory ECG monitoring that emphasizes P-wave signal clarity.

Digital HealthHealthtechMedical DevicesSeattle, US

Gust H. Bardy(Executive Officer, Director, Promoter)Mark Querry(Executive Officer)Kevin Nelson, III(Executive Officer)Rik Vandevenne(Director)Alan Levy(Director)Mark Handfelt(Executive Officer, Promoter)

Board seatPLPaul LaViolette· per SEC Form D

Co-investorsAPAPERTURE Venture PartnersAPAphelion CapitalASAscension VenturesLULumira VenturesRCRC CapitalRERex Health Ventures+2 more

CardioFocus develops Pulsed Field Ablation (PFA) technologies and systems for electrophysiologists to treat complex cardiac arrhythmias with precision and control.

BiotechHealthtechMedical DevicesMarlborough, US

Lauren Jennings(Executive Officer)Warren Clark(Executive Officer)Stephen Sagon(Executive Officer, Director)inARAnjie Roldan(Executive Officer)inWarren R. Clark III(Executive Officer)Stephan S. Ogilvie(CEO)in

Board seatPLPaul LaViolette· per SEC Form D

Co-investorsBIBioBritSASaints CapitalACAccuitive Medical VenturesOXOxford Bioscience PartnersSVSV Life Sciences

Developer of a transcatheter InterAtrial Shunt Device to treat congestive heart failure.

BiotechTewksbury, US

George J. Fazio(Executive Officer, Director)inDan B. Curtis(Executive Officer)

BoardKGKevin Gillis(Director)inGBGerald Brunk(Director)inIYIrit Yaniv(Director)in

Board seatPLPaul LaViolette· per SEC Form D · $11.1M raise · filed Jun 2025

Co-investorsACAccelmed PartnersLULumira VenturesGEGeneral CatalystTHThird Rock Ventures

RejuvenAir, developed by CSA Medical, is a bronchoscopic cryosurgical device that sprays metered doses of liquid nitrogen to destroy damaged airway cells and treat the underlying cause of COPD with Chronic Bronchitis.

HealthtechMedical DevicesLutherville, US

Ellen Sheets(Executive Officer, Director)inIan J. Vawter(Executive Officer)SSSteven Schaefer(Executive Officer)inWilliam Floyd(Executive Officer, Director)inVincent Owens(Director)Richard Kent(Director)

Board seatPLPaul LaViolette· per SEC Form D

Co-investorsASAscension VenturesFIFirst AnalysisNENew Markets Venture PartnersBLBlue Heron CapitalTVTVM CapitalTVTVM Capital Life Science

Endotronix develops the Cordella PA Sensor and Heart Failure System, an FDA-approved implantable pulmonary artery pressure sensor and remote monitoring platform for managing patients with NYHA class III heart failure.

Digital HealthHealthtechMedical DevicesWoodridge, US

HRHarry Rowland(Executive Officer, Director)inANAnthony Nunez(Founder)in

BoardJonathan Jonas(Director)Raymond S. Barrett, Jr.(Director)Sam R. Leno(Director)Leslie A. Saxon(Director)

Board seatPLPaul LaViolette· per SEC Form D

Co-investorsAPAPERTURE Venture PartnersBIBioventures InvestorsJUJumpstart VenturesLULumira VenturesOSOSF VenturesSESeroba Life Sciences+1 more

Lunair Medical develops an implantable closed-loop system that senses respiration and stimulates the phrenic nerve to treat moderate-to-severe sleep apnea, avoiding masks, mouthpieces, and wearables.

Digital HealthHealthtechMedical DevicesMinneapolis, US

MCMark Christopherson(Executive Officer, Director)inHLHoward Levin(Director)

BoardDNDavid Neustaedter(Director)inMHMichael Hurley(Director)

Board seatPLPaul LaViolette· per SEC Form D

Ocular Therapeutix focuses on drug development and treatment for retinal diseases, with an emphasis on wet age-related macular degeneration and expanding into diabetic retinopathy conditions.

BiotechDigital HealthHealthtechMedical DevicesBedford, US

ASAmarpreet Sawhney(Director)Kevin Hanley(Executive Officer)Michael Goldstein(Executive Officer)inDBDaniel Bollag(Executive Officer)Antony Mattessich(Executive Officer, Director)inDNDonald Notman(Executive Officer)in

Board seatCWCharles Warden· per SEC Form D

Co-investorsASAscension VenturesSOSofinnova VenturesTOTop Corner CapitalAGAgent Capital

BiotechHealthtechPompano Beach, US

Laura Tyler Perryman(Director)Regina Groves(Executive Officer, Director)Virginia Sullivan(Executive Officer)Marc Loev(Director)Richard Chen Mao(Director)Gary Perryman(Director)

Board seatPLPaul LaViolette· per SEC Form D · $8M raise · filed Sep 2020

Co-investorsEMEmergent Medical Partners, LLP

Asensus Surgical (formerly TransEnterix) develops robotic-assisted surgical systems and augmented intelligence technology, including reusable instruments, to give surgeons real-time information during procedures.

AI & Machine LearningHealthtechMedical DevicesRoboticsMorrisville, US

AFAnthony Fernando(Executive Officer)inTodd M. Pope(Executive Officer, Director)inJoseph P Slattery(Executive Officer)inJames J. Martin(Executive Officer)Charles J. Filipi(Executive Officer, Director)Jeffrey G. Spragens(Executive Officer, Director)

Board seatPLPaul LaViolette· per SEC Form D

Co-investorsAIAisling CapitalSASaints CapitalQUQuaker BioVenturesSVSV Life Sciences

BiotechMaple Grove, US

JON PATRICK ST. GERMAIN(Executive Officer)DAVID KRENN(Executive Officer)JOHANN NEISZ(Executive Officer, Director)

BoardMARY LINCOLN CAMPBELL(Director)MITCHELL DANN(Director)PAPAUL A. LAVIOLETTE(Director)in

Board seatPLPaul LaViolette· per SEC Form D

Co-investorsKAKaiser Permanente Ventures

Achillion conducts research and development focused on addressing rare disease challenges through investigation of new therapeutic targets, modalities, and technologies.

BiotechHealthtech

Co-investorsCOConnecticut InnovationsPAPappas CapitalDODomain Associates

Adimab develops proprietary platforms for antibody and protein therapeutic discovery, engineering fully-functional immunoglobulins in a controllable in vitro eukaryotic system.

AI & Machine LearningBiotechDeep TechVermont, US

Co-investorsGRGrandBanks CapitalLALaunchCapitalLULux CapitalMIMithril Capital ManagementPRPremji InvestOROrbiMed+1 more

AdvanCell is a clinical-stage radiopharmaceutical company developing a pipeline of targeted alpha therapies for the treatment of cancers including prostate, melanoma, ovarian, breast, and lung.

BiotechHealthtechMedical DevicesCambridge, US

AAAndrew Adamovich(Director)inPLPhilina Lee(Executive Officer, Director)inAPAaron Pickett(Executive Officer)in

BoardWing Cheong Lam(Director)Nik Economopoulos(Director)Anthony Aiudi(Director)

Co-investorsBABain Capital Life SciencesCACatalio Capital Management, LPPRProto AxiomSASanofi VenturesTETenmileABAbingworth+2 more

Allos uses causal AI modeling to optimize pharmaceutical drug formulation and reformulation, mapping chemistry, process variables, and performance data to reduce failed experiments and shorten timelines.

AI & Machine LearningBiotechHealthtech

Co-investorsOAOak Investment Partners

Ally Bridge Group is a healthcare investment management firm investing across the global life sciences industry through complementary private equity and public equity strategies.

BiotechHealthtechMedical DevicesNew York, US

FYFrank Yu(Founder, Chief Executive Officer, Chief Investment Officer)in

Alpheus is a clinical-stage biotechnology company developing Porphyrin Metabolite Activation (PoMA™), a drug-led oncology approach designed to treat glioblastoma using proprietary low-intensity ultrasound to activate tumor-localized porphyrin metabolites.

BiotechHealthtechMedical DevicesChanhassen, US

Jeremy Ling(Executive Officer)inSteve Weiner(Executive Officer)Vijay Agarwal(Founder, President and CEO)inWilliam Davis(Executive Officer, Director)

BoardKVKlaus Veitinger(Director)inIEImran Eba(Executive Officer)in

Co-investorsOROrbiMedHEHealthQuest CapitalSASamsara BioCapitalACAction Potential Venture Capital Ltd.BRBrightEdge

Amphista Therapeutics develops next-generation targeted protein degradation (TPD) medicines using its proprietary Targeted Glue technology, which is engineered to selectively trigger the destruction of disease-causing proteins.

BiotechCambridge, GB

LMLouise Modis(Chief Executive Officer)inMPMartin Pass(Chief Development Officer)inGBGiles Brown(Executive VP Drug Discovery)in

Co-investorsADAdvent Life SciencesNONovartis Venture FundDEDementia Discovery FundEUEuropean Investment FundFOForbionGIGilde Healthcare+2 more

The site presents ICON, a clinical research organization providing full-service drug development outsourcing, regulatory strategy, and clinical trial solutions for pharmaceutical and biotech sponsors.

AI & Machine LearningBiotechHealthtech

Co-investorsHAHalifax Group

Artios develops DNA damage response (DDR)-based medicines targeting patients with high unmet need cancers.

BiotechHealthtechMedical Devices

Co-investorsANAndera PartnersDEDementia Discovery FundM M VenturesNONovartis Venture FundPFPfizer Venture InvestmentsRARA Capital+6 more

AstronauTx is a biotechnology company focused on drug discovery and development for neurodegenerative and neuroinflammatory diseases, working across small molecules and biologics.

BiotechDeep TechHealthtechLongevityMedical Devices

JRJane Rhodes(Chief Executive Officer)inMIMagnus Ivarsson(Chief Scientific Officer)inHPHannah Pearce(Chief Operating Officer)inMichelle L. Mellion(Chief Medical Officer)in

Co-investorsDEDementia Discovery FundMPMPM BioImpactNONovartis Venture FundUCUCL Technology FundALAlbionVC

Autifony Therapeutics is a privately funded biopharmaceutical company developing treatments for neurological conditions including Fragile X Syndrome and orphan epilepsy syndromes.

BiotechHealthtechMedical DevicesStevenage, GB

Charles H. Large(Founder and Chief Executive Officer)inGiuseppe Alvaro(Director)Daniel UmbrichtBarbara Domayne-HaymanMartin GunthorpeHannah Selin

Co-investorsPFPfizer Venture InvestmentsDEDementia Discovery FundINInnovate UK

AviadoBio is a gene therapy company developing adeno-associated viral (AAV) treatments for neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

BiotechDeep TechDigital HealthHealthtech

CSChris Shaw(Co-Founder & Chief Scientific and Clinical Advisor)inDYDo Young Lee(Co-Founder)YBYoun Bok Lee(Co-Founder)inLDLisa Deschamps(Chief Executive Officer)inGFGraeme Fielder(Chief Operating Officer)inABAlex Bloom(Chief Development Officer)in

Co-investorsADAdvent Life SciencesDEDementia DiscoveryF-F-Prime CapitalLILifeArc VenturesMOMonograph Capital PartnersNENew Enterprise Associates (NEA)

Repligen provides bioprocessing technologies—including process intensification, tangential flow filtration, chromatography, process analytics, and single-use fluid management—for upstream and downstream biopharmaceutical workflows.

BiotechHardwareMedical DevicesLebanon, US

TGTillman Gerngross(Director)EAErrik Anderson(Director)inWarren Kett(Executive Officer)Jon Sheller(Executive Officer)Kevin Issett(Executive Officer, Director)Kevin Isett(Executive Officer, Director)

Co-investorsOROrbiMedBOBorealis VenturesMIMithril Capital ManagementNENeomed ManagementPOPolaris PartnersSASands Capital Ventures+1 more

AVROBIO develops ex vivo lentiviral vector-based hematopoietic stem cell gene therapies to treat lysosomal disorders by permanently integrating therapeutic genes into patient stem cells manufactured outside the body.

BiotechDigital HealthHealthtechMedical Devices

Brixton Bio develops Reneurx therapy, a treatment aimed at providing long-lasting pain relief for up to six months from a single administration.

BiotechMedical Devices

CSCharles Sidoti(Founder)in

Co-investorsANAngel Physicians FundCACatalyst Health VenturesEXExcelestar VenturesFEFemHealth VenturesSCSchooner CapitalSPSparta Group

Caraway Therapeutics was a preclinical biopharmaceutical company developing small-molecule therapies modulating lysosomal function to treat neurodegenerative and rare diseases.

BiotechHealthtech

Co-investorsDEDementia Discovery FundEIEisai Innovation, Inc.MCMcCarthy CapitalMRMRL Ventures FundABAbbVieBRBridge Investments+8 more

CarePredict offers a platform that detects patterns in the daily activities of older adults to signal health changes and enable early intervention.

AI & Machine LearningDigital HealthHealthtechLongevityPlantation, US

SMSatish Movva(Founder)inPeter Livingston(Director)DHDean Hatton(Director)inMarc Loev(Director)

Co-investorsHEHealthtech CapitalLALas Olas Venture CapitalVIVillage GlobalMIMiami Angels

Celerion is a contract research organization specializing in early phase clinical drug development, providing bioanalytical services and laboratory testing that generate clinical data for pharmaceutical clients.

BiotechDigital HealthHealthtechMedical DevicesLincoln, US

Co-investorsAEAea InvestorsBABain Capital VenturesH.H.I.G. CapitalH.H.I.G. HealthBridge PartnersTHTHL FUND

Centauri provides data-driven technology and services for U.S. health plans and health systems, turning fragmented clinical data into analytics used for risk adjustment, care coordination, quality optimization, and clinical data exchange.

Data & InfrastructureDigital HealthHealthtech

MMMike McNelis(Founder)in

Co-investorsABABRY PartnersDEDementia Discovery FundSISilversmith Capital Partners

Cerevance develops precision novel therapeutics for central nervous system disorders, particularly neurodegenerative diseases, using its proprietary NETSseq platform and machine learning to identify targets from an extensive collection of human brain tissue samples.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesBoston, US

CTCraig Thompson(Chief Executive Officer)inSVSagar Vaidya(Chief Medical Officer)inCarrie Ann Cook(Chief Business Officer)MCMark Carlton(Chief Scientific Officer)inOVOttavio V. Vitolo(Chief Medical Officer)in

Co-investorsDEDementia Discovery FundFOForesite CapitalGVGV (Google Ventures)SVSV Life SciencesDEDementia DiscoveryDODolby Family Ventures+3 more

Cumulus manufactures a cold coffee brewing machine that produces cold brew, nitro, and cold espresso on demand, sold direct to consumers alongside specialty coffee capsules and accessories.

ConsumerHardwareNew York, US

Mesh Gelman(Founder)in

BoardJSJonathan Shulkin(Director)DLDan Levitan(Director)in

Co-investorsMAMaveronBRBrick Mortar VenturesINInvesting Women AngelsSHShell VenturesVAValor Equity Partners

EMED makes infusion pump systems and subcutaneous delivery devices for patients requiring immunoglobulin therapy and other biologics.

Digital HealthHardwareHealthtechMedical Devices

Phil Parvin MBAin

EpiVax works with biologic and vaccine developers to assess and manage immunogenicity risk across the product lifecycle, combining in silico analysis with in vitro testing to produce actionable immunogenicity data.

AI & Machine LearningBiotechHealthtech

ADAnnie De Groot MD(Founder)inRSRich-Henry Schabowsky, PhD, JDin

BiotechCambridge, US

JGJennifer Glennon(Executive Officer)inBalkrishan (Simba) Gill, Ph.D.(Executive Officer, Director)Duncan McHale(Executive Officer)inWDWilliam DeVaul(Executive Officer)inMark Bodmer, Ph.D.(Executive Officer)

BoardNoubar B. Afeyan, Ph.D.(Director)

Co-investorsGVGV (Google Ventures)ALAlexandriaFLFlagship PioneeringKAKaiser Permanente VenturesMAMayo Clinic Ventures

Evidation collects and analyzes real-world health data from millions of community members to enable clinical research and health programs across various medical conditions.

BiotechData & InfrastructureDigital HealthHealthtechSan Francisco, US

CLChristine Lemke(Executive Officer, Director)inDKDeborah Kilpatrick(Executive Officer, Director)LOLeslie Oley Wilberforcein

BoardDavid Fleshman(Director)RCRowan Chapman(Director)in

Co-investorsASAsset Management CompanyB B Capital GroupB4B4 CapitalCRCross Creek AdvisorsDEDementia Discovery FundFRFresco Capital+6 more

EyeBio (Eyebiotech Limited), a subsidiary of Merck, develops therapies for retinal diseases such as diabetic macular edema and neovascular age-related macular degeneration, targeting vascular leakage through pathways like Wnt signaling.

BiotechHealthtechHolborn, London

David R. Guyer(Founder, CEO & President)Anthony P. Adamis(Chief Scientific Officer, Co-founder, Director & Chair of Advisory Board)James Allister John Costine(Director)Michael Jay Ross(Executive Officer)Catherine Elizabeth Bingham(Director)

Co-investorsJEJeito CapitalSASamsara BioCapitalOMOmega Funds

Homecare Homebase (HCHB) offers a suite of AI and analytics extensions built into its home health and hospice software, providing reporting dashboards, patient intake, rehospitalization risk prediction, automated scheduling, and ambient clinical documentation.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechMedical DevicesSaaS

DMDr. Martha Stuart Williams(Chief People Officer)Isaac(Vice President of Technology Operations)

Imbria Pharmaceuticals develops novel cardiovascular disease treatments that target cardiac energy metabolism, with a lead drug candidate, ninerafaxstat, in clinical trials for non-obstructive hypertrophic cardiomyopathy.

BiotechDigital Health

ASAlvin Shih(CEO)inAMAlbert M. Kim(Chief Medical Officer)in

Co-investorsANAN Venture PartnersCACatalio Capital Management, LPRARA CapitalSASanofi VenturesCACatalio Capital Management

Kinaset Therapeutics is a drug developer working on KN-002, a therapeutic candidate for treating severe asthma across patients regardless of the underlying cause of inflammation.

BiotechHealthtechMedfield, US

RHRoger Heerman(Chief Business/Operating Officer / Co-Founder)inFMFrazer Morgan(Chief Development Officer / Co-Founder)inRCRobert Clarke(Chief Executive Officer / Board Member / Co-Founder)Christopher O’Brien(Chief Medical Officer)

BoardJBJamil Beg(Director of the Issuer)inTom King(Director of the Issuer)

Co-investors5A5AM VenturesATAtlas VentureRARA CapitalEQEQT Life SciencesGIGimvSISixty Degree Capital+3 more

Leal Therapeutics is a company focused on CNS (central nervous system) disorders, drawing on academic and drug-development experience in neurology and neurodegenerative disease.

BiotechHealthtechMedical DevicesWorcester, US

AAAsa Abeliovich(CEO & Founder, Director)

Co-investorsOROrbiMedABAbbVieDEDementia Discovery FundNENewpath Partners

Leica Microsystems manufactures optical microscopy instruments and fluorescence reagents for scientific research and diagnostics.

BiotechDeep TechHardwareHealthtechMedical DevicesWetzlar, DE

Co-investorsARArieal Southeast Angel Partners

Leiters Health is an FDA-registered 503B outsourcing facility that produces sterile compounded preparations for hospitals, surgery centers, and ophthalmic use.

BiotechHealthtechMedical DevicesDenver, US

Co-investorsCOCorewell Health VenturesDEDementia Discovery FundESEscalate Capital PartnersFRFrazier Healthcare PartnersH.H.I.G. CapitalH.H.I.G. HealthBridge Partners+4 more

LoQus23 Therapeutics is a drug discovery company developing treatments for triplet repeat expansion diseases such as Huntington's disease, focused on preclinical CNS and neuroscience research.

BiotechDeep TechCambridge, GB

DRDavid Reynolds(Co-founder & CEO)inCBCaroline Benn(Co-founder & CSO)in

Co-investorsDEDementia Discovery FundNONovartis Venture FundFOForbion

Miach Orthopaedics develops implants that help the body restore its own connective tissue, with an initial focus on treating ACL tears.

HealthtechMedical DevicesWestborough, US

MMMartha Murray(Founder)inCJChris Joyce(Executive Officer)inPMPatrick McBrayer(Executive Officer, Director)inSean Sansiveri(Director)Pieter Wolters(Director)

BoardMarc-Andre Marcotte(Director)

Co-investorsAMAmzak HealthAPAPERTURE Venture PartnersENEndeavour Vision

Mindframe builds AI-powered technology for behavioral health practitioners to enhance clinical care delivery and patient engagement in regulated healthcare environments.

AI & Machine LearningDigital HealthHealthtechMental HealthLondon, GB

PGPinar Gorgulu(CEO & Co-founder)inFaye Cheung, PhD(CTO & Co-founder)in

Co-investorsTETechstars

Montara is a biotech company developing small-molecule therapeutics focused on neurodegeneration and diseases such as Alzheimer's.

AI & Machine LearningBiotechDeep TechSan Francisco, US

KSKevan Shokat(Co-Scientific Founder & Chairman of the SAB)TSThomas Südhof(Co-Scientific Founder & SAB Member)Seth Stratton(Director)Dirk Langdorf(Director)Nicholas Hertz(Executive Officer, Director)

Co-investorsBEBEVCDODolby Family VenturesTWTwo Bear CapitalDEDementia Discovery FundKDKdT Ventures

Modern Systems Talk (MST) publishes content and insights on technology topics including system architecture, cloud computing, automation, AI, cybersecurity, and digital transformation.

Media & Entertainment

Co-investorsAGAgate Medical Investments LPSCSCP Vitalife PartnersFOForbionGVGV (Google Ventures)NONorthpond Ventures

Nanopath is developing a molecular diagnostic platform for point-of-care disease diagnosis, with a focus on women's health.

BiotechFemTechMedical DevicesCambridge, US

Alison Burklund(Executive Officer, Director)inAmogha Tadimety(Executive Officer, Director)in

BoardASAaron Sandoski(Director)inJCJeff Crowe(Director)in

Co-investorsALAlumni VenturesNONorwest Venture PartnersSEService Provider CapitalUNUndeterred CapitalGIGingerbread CapitalGRGreen D Ventures+2 more

The NFLPA is the labor union representing players of the National Football League, working on their success and well-being both on and off the field.

Sports Tech

Nimbus develops wireless power technology that uses invisible infrared LED light to transmit energy across a room, with a receiver that converts the light into electricity to charge laptops, phones, and other devices.

Deep TechEnergyHardware

Michael Gorman(Founder)in

Co-investorsFOFoothill VenturesACAccess BiotechnologyATAtlas VentureBABain Capital Life SciencesBIBiotechnology Value FundCOCommodore Capital+2 more

FuseBase is an enterprise platform for deploying and managing AI agents across teams with role-based access controls, audit trails, and integrations to CRM, Slack, Teams, and email systems.

AI & Machine LearningEnterprise SoftwareFuture of WorkSaaSCleveland, US

Pavel Sher(CEO)Aaron Adsit(CRO)Denis Kibalko(CTO)

Co-investorsPRPre-Seed to SucceedYEYellow Rocks!ACAccess BiotechnologyATAtlas VentureBABain Capital Life SciencesBIBiotechnology Value Fund+3 more

Nimbus Therapeutics is a biotechnology company that designs precision small molecule medicines using a computational, multidisciplinary drug discovery approach.

AI & Machine LearningBiotechDeep TechHealthtech

Co-investorsACAccess BiotechnologyATAtlas VentureBABain Capital Life SciencesDEDementia Discovery FundGVGV (Google Ventures)LILightstone Ventures+4 more

Nira Medical consolidates independent neurology practices across the United States to improve patient access to neurological care.

Digital HealthHealthtechMedical Devices

Co-investorsSISilversmith Capital PartnersTRTRANSFORMATION CAPITAL

Nitrase Therapeutics is a clinical-stage biopharmaceutical company using its NITROME platform to develop therapeutics based on nitrases, a class of enzymes it discovered that drive protein nitration.

BiotechHealthtechLongevity

Irene Griswold-Prenner(Founder & Chief Executive Officer)in

Co-investorsDEDementia Discovery FundMIMission BiocapitalSOSofinnova PartnersABAbbVieMIMission Bay Capital

Nuwellis develops medical technology solutions for managing fluid overload in patients with cardiorenal conditions, serving clinicians and healthcare providers in inpatient and outpatient settings.

BiotechHardwareHealthtechMedical DevicesEden Prairie, US

Rob Scott(Executive Officer)inNJNestor Jaramillo, Jr.(Executive Officer, Director)inBrian Brown(Executive Officer)David A. Rosa(Executive Officer, Director)CDClaudia Drayton(Executive Officer)inDebra J. Kridner(Executive Officer)

Co-investorsASAscension VenturesKAKaiser Permanente Ventures

Onkos Surgical develops limb salvage and orthopedic reconstruction implants and systems for treating musculoskeletal cancer and complex orthopedic conditions.

HardwareHealthtechMedical DevicesParsippany, US

PTPatrick Treacy(Founder)inAntony Koblish(Director, Promoter)inBTBrad Tyler(Executive Officer)in

BoardAOAdele Oliva(Director)inStephen Bloch(Director)inPaul Touhey(Director)

Co-investors131315 CapitalCACanaan PartnersJSJSD Capital, LLCRORocky Point Ventures

BiotechNew York, US

DGDavid Guyer(Executive Officer, Director)GSGlenn Sblendorio(Executive Officer, Director)MAMike AtiehinDavid Redlick(Director)Keith Westby(Executive Officer)David Carroll(Executive Officer)

Co-investorsSOSofinnova VenturesCLClarus VenturesSVSV Life Sciences

BiotechMt. Arlington, US

Paul Chaney(Executive Officer, Director)

BoardACAbbie Celniker(Director)inDavid Guyer(Director)BPBruce Peacock(Director)KSKevin Starr(Director)inLutz Giebel(Director)

Co-investorsASAstellas Venture Management LLCAGAgent CapitalSVSV Life SciencesTHThird Rock Ventures

PayMedix simplifies healthcare payments by paying providers in full for allowed in-network claims and streamlining patient billing, improving access to care regardless of financial status.

Digital HealthEnterprise SoftwareFintechHealthtech

Tom Policelli(Chief Executive Officer)inBMBrian Marsella(President)in

Co-investorsHLHLM Investment Partners

Perfuze develops medical devices for the treatment of acute ischemic stroke, focused on addressing unmet clinical needs in mechanical thrombectomy.

Deep TechHealthtechMedical DevicesGalway City, IE

WAWayne Allen(Co-Founder, CEO, Director)inLMLiam Mullins(CTO and Co-founder)in

Co-investorsSESeroba Life SciencesBEBek VenturesENEnterprise IrelandEQEQT Life Sciences

Pivot Point Consulting provides managed IT services, EHR consulting, strategic advisory, analytics and AI solutions, and ERP implementation services to healthcare organizations.

AI & Machine LearningEnterprise SoftwareHealthtechSaaS

Podimetrics offers a remote monitoring and care program for people with complex diabetes, centered on the SmartMat device that collects foot-health data to enable early intervention and prevent complications such as amputations.

Digital HealthHealthtechMedical DevicesSomerville, US

DLDavid Linders(Executive Officer, Director)inJonathan Bloom(Executive Officer, Director)

BoardASAaron Sandoski(Director)in

Co-investorsNONorwich VenturesSCScientific Health DevelopmentPOPolaris PartnersRORock Health

Prilenia is a biotechnology company developing treatments for neurodegenerative diseases, including Huntington's disease and amyotrophic lateral sclerosis (ALS).

BiotechHealthtechMedical Devices

Co-investorsALALS Investment FundAMAmplitude Venture CapitalFOForbion

Pulmocide is a biopharmaceutical company developing inhaled therapies for difficult-to-treat respiratory diseases, currently focused on respiratory fungal infections such as pulmonary aspergillosis.

BiotechHealthtech

PSPete Strong(Co-founder)Garth Rapeport(Co-founder)inKazuhiro Ito(Co-founder)inJohn Murray(Co-founder)inDMDavid Mantusin

Co-investorsADAdjuvant CapitalASAsahi Kasei Corporate Venture CapitalDEDementia Discovery FundF-F-Prime CapitalJEJeito CapitalLOLongwood Fund+4 more

Quell Therapeutics is a clinical-stage biopharmaceutical company developing targeted Treg cell therapies with advanced manufacturing capabilities.

BiotechDeep TechHealthtechMedical Devices

Co-investorsALAlbionVCJEJeito CapitalUCUCL Technology Fund

QurAlis develops precision therapies for amyotrophic lateral sclerosis (ALS) and related neurodegenerative diseases by targeting specific disease-causing genetic drivers and molecular mechanisms.

BiotechDeep TechMedical DevicesCambridge, US

KEKevin Eggan(Founder, QurAlis; Group Vice President, Head of Research and Early Development, BioMarin Pharmaceutical)inRoet(Co-founder)Woolf(Co-founder)KRKasper Roet(Founder, Chief Executive Officer)inSVShafique Virani(Executive Officer)inJBJason Brown(Mr. Brown is the Chief Financial Officer of the Issuer.)in

Co-investorsALALS Investment FundDODolby Family VenturesDRDroia VenturesINInkefMCMC Healthcare VenturesMIMission Biocapital+8 more

Ria Health provides telemedicine-based treatment for alcohol and opioid use disorders, delivered by a team of physicians, nurse practitioners, and counselors.

Digital HealthHealthtechMental HealthWellness & FitnessSan Francisco, US

BSBill Stapleton(CEO)in

Co-investorsSOSOSV

BiotechGreenville, US

KWKevin Weeks(Executive Officer, Director)Katherine Warner(Executive Officer)Joshua Resnick(Director)Michael Solomon(Director)John Gustofson(Director)

BoardMike Dial(Director)in

Co-investorsHAHatteras Venture PartnersILIllumina VenturesM M VenturesMCMC Healthcare VenturesPAPappas CapitalABAbbVie+2 more

Rondo Therapeutics is an immuno-oncology biopharmaceutical company developing bispecific/multispecific antibody therapeutics designed for tumor-selective targeting to treat solid tumors while sparing healthy tissue.

BiotechHealthtech

SFShelley Force Aldred(Co-Founder & Chief Executive Officer)inNTNathan Trinklein(Co-Founder, President & CSO)inKatherine(Chief Development Officer)Thomas(Chief Medical Officer)

Co-investorsCACanaan PartnersDEDementia Discovery FundRERed Tree VentureJOJohnson & Johnson Innovation – JJDCNONovo Holdings