Fundraising Fox

S3 Ventures

Venture capitalActively deploying

Austin · Seed–Series B · 17 people tracked

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Investment thesis

S3 Ventures invests in technology companies solving major business problems—spanning software applications, IT infrastructure, developer tools and platforms, hardware, and other tech-driven products—as well as companies improving the human condition through medical devices and health software, from diagnostics and treatment to wellness. Backed by a single philanthropic limited partner, the firm positions itself as a patient, flexible investor free from traditional fundraising pressures. It leads Seed, Series A, and Series B rounds with initial checks of $500K to $15M+ and the capacity to invest $25M+ over the life of a company.

Source: firm website, verified Aug 23, 2026.

Stage
Seed–Series B
Check
$500K – $15M
HQ
Austin, Texas, US
Leads rounds
Leads
Instruments
Equity
Founded
2005
Last 12 months
9 investments
AUM
$1B
Tracked investments
141

Team · 17 people

from the firm's website & public directories
Stephen Banks· Venture Partnerin
Anthony Marfski· Associate

Founder mafia

2 people who came through S3 Ventures went on to found or lead other companies.

What they invest in

from 38 of 141 portfolio companies

SaaS ×19AI & Machine Learning ×13Enterprise Software ×12Healthtech ×9Fintech ×8Data & Infrastructure ×7Cloud Computing ×5Cybersecurity ×4

HQs:United States×47

Who they back

founder profiles across 16 portfolio companies
44%
solo founders
7 of 16 mapped founding teams
~4 yrs
old at investment
median across 16 dated deals

Founding team size:solo founder×72 founders×63 founders×24+ founders×1

Accelerator rootsportfolio companies that came through a program

Techstars ×2Y Combinator ×2

Investments · 141 tracked

founders shown can be your intro path

By year:2026 · 62025 · 82024 · 42023 · 32022 · 22021 · 12020 · 12019 · 12018 · 12017 · 22015 · 22014 · 233 dated

ALKAMI TECHNOLOGY, INC.NASDAQ: ALKTOct 2020SEC filinghigh confidence

Plano, US

Gary Nelson(Director)David Becker(Executive Officer)Jeff Chambers(Executive Officer)Hansen C. Michael(Executive Officer, Director)Jeffery Chambers(Executive Officer)

BoardBrian R. Smith(Director)in

Board seatBrian SmithCharlie Plauche· per SEC Form D · $140M raise · filed Oct 2020

VUV Analyticsvuvanalytics.comin𝕏Nov 2022✓ verified

VUV Analytics develops vacuum ultraviolet (VUV) spectroscopy instruments and detectors for chemical analysis, including detectors for gas and liquid chromatography used in analytical laboratories.

Deep TechHardwareNew MaterialsCedar Park, US

Dale Harrison(Executive Officer)Sean Jameson(Executive Officer, Director)Joseph H. Timko(Director)Kirk Patterson(Executive Officer)Clark Jernigan(Executive Officer, Director)

Board seatBrian SmithEric Engineer· per SEC Form D

Co-investorsNew Science Ventures

Liquibaseliquibase.cominMar 2025 · $10M✓ verified

Liquibase provides a platform for governing and automating database change management across pipelines, platforms, and teams, integrating with tools like ServiceNow, GitHub, Harness, and Terraform.

Data & InfrastructureDeveloper ToolsEnterprise Software

Robert(Co-founder)Pete(Co-founder)Nathan(Founder (Liquibase open-source project))Patti(Chief Executive Officer)Ryan(Chief Customer Officer / Customer Success)Steve Surace(Vice President of Engineering)

Co-investorsRiver Cities CapitalMercury Fund

Mythic AImythic.aiin𝕏✓ verified

Mythic builds analog processing units based on compute-in-memory architecture designed to run AI workloads efficiently in real-world applications.

AI & Machine LearningHardwareSemiconductorsPalo Alto, US

Taner Ozcelik(CEO / Board Member)Steven Pho(CFO)

Co-investorsCatapult VenturesNew Enterprise Associates (NEA)Atreides ManagementDCVC (Data Collective)Linse CapitalLockheed Martin Ventures+6 more

Spectrawavespectrawave.comin𝕏May 2019✓ verified

SpectraWAVE develops optical and computational imaging technologies to diagnose and guide treatment decisions for patients with coronary artery disease and cardiovascular disease.

AI & Machine LearningDeep TechHealthtechMedical DevicesBedford, US

Eman Namati(President & CEO)Guillermo Tearney(Founder; Professor of Pathology, Massachusetts General Hospital)Gregg Stone(Founder; Professor of Medicine, Mount Sinai Heart Health System)James Muller(Founder; Cardiologist, Brigham and Women's Hospital)Jeffrey O'Donnell(Founder; Managing General Partner, Runway Healthcare)Vivek Walimbe(Chief Operating Officer)

Co-investorsLumira VenturesSV Health InvestorsDeerfield Management CompanyJohnson & Johnson Innovation – JJDC

Arpioarpio.ioin𝕏Aug 2023 · $15M

Arpio provides an automated disaster recovery platform purpose-built for AWS and Azure cloud applications.

Cloud ComputingCybersecurityData & InfrastructureEnterprise SoftwareSaaSDurham, US

Doug Neumann(Founder)inShaw Terwilliger(Founder)in

Board seatEric Engineer· per SEC Form D

Co-investorsCompanyon VenturesCreativeCoDraper AssociatesIDEA NCY CombinatorLookout Ventures+2 more

BrainCheckbraincheck.comin𝕏Jan 2024

BrainCheck offers a platform for cognitive assessment and care planning, centered on an FDA-registered Class II digital cognitive assessment plus over 30 clinical evaluation tools that integrate into clinical workflows and EHR systems like Epic and athenahealth.

Digital HealthHealthtechMedical DevicesSaaSHouston, US

Yael Katz(Executive Officer, Director)inDavid Eagleman(Executive Officer, Director)Andrew Chen(Founder)in

Board seatCharlie Plauche· per SEC Form D

Co-investorsBlue Hour VenturesNext Coast VenturesNueterra CapitalTensility Venture PartnersTrue Wealth Ventures

BriggoAug 2018

Austin, US

J. Kevin Nater(Executive Officer, Director)Scott Schaefer(Executive Officer)Stephen Smith(Executive Officer)John Craparo(Executive Officer)Kevin Nater(Executive Officer, Director)Charles Studor(Executive Officer, Director)

Board seatEric Engineer· per SEC Form D

Earlytrade US Holdings Corp.Jun 2026SEC filingmedium confidence

Denver, US

David Saxelby(Director)Scott Spolansky(Executive Officer)Guy Saxelby(Executive Officer, Director)

BoardAnthony Millet(Director)

Board seatCharlie Plauche· per SEC Form D · $17.6M raise · filed Jun 2026

Co-investorsAntlerBrick Mortar Ventures

Engaged Citizen Inc.Jan 2026SEC filingmedium confidence

Denver, US

Jeremy Becker(Executive Officer, Promoter)Adam Zucker(Executive Officer, Director, Promoter)Taylor McLemore(Director)

BoardPeter Solvik(Director)in

Board seatCharlie Plauche· per SEC Form D · $8.8M raise · filed Jan 2026

Co-investorsJackson Square Ventures

Interplay Learninginterplaylearning.comin𝕏Sep 2024

Interplay Learning builds online skilled trades courses designed and delivered by industry experts and instructional designers, covering foundational technical knowledge and real-world applications for technicians.

EdTechEnterprise SoftwareFuture of WorkHR TechSaaSAustin, US

Sam Decker(Director)Douglas Donovan(Executive Officer, Director)Richard Waitumbi(Director)Kimberly Caldbeck(Director)

BoardIan Chiu(Director)

Board seatCharlie Plauche· per SEC Form D

Co-investorsCathexis VenturesCentral Texas Angel NetworkCerity Partners VenturesOwl VenturesSierra VenturesSJF Ventures+3 more

Kamiwazakamiwaza.aiinJan 2025

Kamiwaza offers a distributed AI orchestration platform that processes data where it resides, allowing enterprises to deploy AI without centralizing data or compromising security.

AI & Machine LearningData & InfrastructureEnterprise SoftwareGovTechSilverthorne, US

Matthew Wallace(Executive Officer, Director)Luke Matthew Norris(Executive Officer, Director)

Board seatEric Engineer· per SEC Form D

Co-investorsAscend Venture CapitalCitta CapitalFirstMile VenturesGreater Colorado Venture FundAscendPioneer Square Ventures

MontyCloudmontycloud.comin𝕏Jan 2026

MontyCloud is a no-code, autonomous CloudOps platform that helps IT teams optimize and operate cloud services using intelligent automation and AI.

AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise SoftwareRedmond, US

Venkat Krishnamachari(Chief Product Officer & Co-Founder)Kannan Parthasarthy(Chief Technology Officer & Co-Founder)Rajkumar Sivarajan(Executive Officer)Walter A. Rogers(Executive Officer, Director)VENKATESWARAN HARIHARA SUBRAMANIAN(Executive Officer)

BoardSteve Berg(Director)in

Board seatEric Engineer· per SEC Form D

Co-investors1809 CapitalMadrona Venture GroupRaptor GroupRiverside Acceleration CapitalLytical Ventures

Prokeepprokeep.cominNov 2024

Prokeep offers a centralized communication platform that lets parts departments handle customer messages across text, email, fax, and web chat, with features like picture messaging, automated order status updates, and inventory checks.

AI & Machine LearningLogistics & Supply ChainMarketing TechSaaSSales TechNew Orleans, US

McKay Johnson(Founder)inMark Kanof(Founder)inScott Wolfe(Director)John F. Carrere, III(Executive Officer, Director)John Giannuzzi(Director)

BoardTy Findley(Director)

Board seatCharlie Plauche· per SEC Form D

Co-investorsCallais Capital ManagementIronspring Venture

QbDVisionqbdvision.comin𝕏Apr 2025

QbDVision offers a Digital CMC (Chemistry, Manufacturing, and Controls) SaaS platform that captures structured, versioned pharmaceutical development data and provides end-to-end product lifecycle management from R&D through commercial manufacturing.

BiotechHealthtechSaaSAustin, US

Board seatEric Engineer· per SEC Form D

Co-investorsCartmell VenturesCREATE HEALTH VENTURES

Rarefied Atmosphere, Inc.Feb 2023SEC filingmedium confidence

Austin, US

Leo Resig(Executive Officer, Director, Promoter)John Resig(Executive Officer, Director, Promoter)Jon Shulkin(Director)Mike Grisko(Executive Officer)

Board seatCharlie Plauche· per SEC Form D · $105M raise · filed Feb 2023

Co-investorsTrinity Capital

RepVuerepvue.comJun 2022

Chapel Hill, US

RYAN WALSH(Executive Officer, Director)M. SCOT WINGO(Director)

BoardRICHARD FRAIM(Director)in

Board seatEric Engineer· per SEC Form D

Co-investorsAlerion VenturesKnoll VenturesGTMfundTDF Ventures

SchematicMar 2026

Boulder, US

Board seatCharlie Plauche· per SEC Form D

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Acessa HealthJun 2017

HealthtechAustin, US

Kim Bridges-Rodriguez(Executive Officer, Director)inIan Ratcliffe(Director)Joe S Andrasko(Director)Jeremy McFadden(Executive Officer)

BoardBrian R Smith(Director)in

Advanced Nanotherapies
Alkamialkami.comin𝕏

Alkami is a digital banking software platform for financial institutions including community and regional banks and credit unions.

Data & InfrastructureEnterprise SoftwareFintechMarketing TechSaaS

Mike Shootman(President and Chief Executive Officer)

Co-investorsMissionOGPlains Ventures

Alleviant
Alleviant Medical Incalleviantmedical.comin𝕏Feb 2025

Alleviant Medical develops an investigational minimally invasive medical device using interatrial shunt therapy to treat heart failure patients, currently in FDA-approved clinical trials (ALLAY-HF and ALLAY-HFrEF).

BiotechHealthtechMedical DevicesAustin, US

Adam Berman(Executive Officer, Director)Jacob Kriegel(Executive Officer, Director)Avni Patel(Executive Officer, Director)Christopher Alex Arevalos(Executive Officer, Director)Albertien Greijdanus(Executive Officer, Director)

BoardGeoff Pardo(Director)

Co-investorsBroadview VenturesRiverVest Venture PartnersTMC Venture FundCadence Healthcare VenturesGilde HealthcareGilmartin Capital LLC+1 more

Allstacksallstacks.comin𝕏

Allstacks is an AI-agent platform that connects data from software development tools (Jira, GitHub, GitLab, Jenkins) to provide engineering teams and leaders with delivery metrics, risk alerts, and recommendations for planning, managing, and optimizing software creation.

AI & Machine LearningDeveloper ToolsEnterprise SoftwareRaleigh, US

Jeremy Freeman(Founder)Hersh A. Tapadia(Executive Officer, Director)Hersh Tapadia(Founder)inDarrell J. Freeman, Jr.(Executive Officer, Director)Scot Sherwood(Director)

BoardAndrew Drylie(Director)in

Co-investorsAtlassian VenturesCompanyon VenturesCreativeCoFirst Rays Venture PartnersGutbrain VenturesHyperplane Venture Capital+7 more

Atmosphere TV

Co-investorsSageview Capital

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Buildforcebuildforce.comin

Buildforce runs a platform that matches electrical contractors with pre-vetted, background-checked electricians for short-term or temp-to-hire work, and handles onboarding, GPS time tracking, compliance, and payroll.

B2B MarketplacesConstruction TechHR TechHouston, US

Vu Brown(Founder)

PartnerAaron Perman· led

Co-investorsGrid CapitalMercury FundTDF Ventures

Business Technology (Austin + Dallas, TX)
Business Technology (Austin, TX - 1)
Business Technology (Austin, TX - 2)
Business Technology (Austin, TX - 3)
Business Technology (Austin, TX - 4)
Business Technology (Austin, TX - 5)
Business Technology (Austin, TX - 6)
Business Technology (Austin, TX - 7)
Business Technology (Austin, TX - 8)
Business Technology (Austin, TX - 9)

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 2

IPOs and acquisitions across the tracked portfolio

ALKAMI TECHNOLOGY, INC.NASDAQ: ALKTOutbound Engineacq. by Elm Street Technology

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has S3 Ventures made?
S3 Ventures has 122 tracked investments, 1 of which have exited via acquisition or IPO, including 8 dated in the last 24 months.
What stage does S3 Ventures invest at?
S3 Ventures invests at the Seed, Series A, Series B stages.
What is S3 Ventures's typical check size?
S3 Ventures typically writes checks of $500K – $15M.
What sectors does S3 Ventures focus on?
S3 Ventures focuses on Cloud Computing, Construction Tech, Data & Infrastructure, Developer Tools, Digital Health, Enterprise Software, Hardware, Healthtech, Medical Devices, SaaS.
Where is S3 Ventures located?
S3 Ventures is headquartered in Austin, US.
Does S3 Ventures lead rounds?
Yes, S3 Ventures leads investment rounds.
Who does S3 Ventures co-invest with?
S3 Ventures most often shares deals with Next Coast Ventures, M12 (Microsoft's Venture Fund), Silverton Partners, among 66 tracked co-investors.

Media · Podcasts & interviews

featuring the team

Aaron Perman, Partner at S3 Ventures on B2B, Healthcare & TX Startups

Grace Gong · Aaron Perman

FIESTA November 2023 - Aaron Perman - S3 Ventures

🎉 FIESTA Community 🎉 · Aaron Perman

Episode 12: How to Land Funding in Today’s Environment w/S3 Ventures’ Eric Engineer

Merritt Group · Eric Engineer

Images

S3 Ventures photo

Co-investors · 41

Next Coast Ventures

Next Coast Ventures is a venture capital firm founded by former operators that uses thematic research to invest in and support high-growth startups.

$2M – $4M
Owl Ventures

Owl Ventures is a Silicon Valley-based venture capital firm with over $2 billion in assets under management that invests in education technology companies serving PreK-12, higher education, career mobility, and professional learning sectors. The firm also invests in companies at the intersection of education technology and other industries.

$5M – $50M
Silverton Partners

Silverton Partners is an early-stage venture capital firm based in Texas that partners with founders long-term, having backed 75+ portfolio companies with 30+ acquisitions and 4 IPOs.

Both backed · 2
$200K – $2M
RiverVest Venture Partners

RiverVest Venture Partners is a life sciences venture capital firm that invests in biotechnology and medical companies, working with entrepreneurs to advance therapeutic and medical innovations.

$500K – $3M
Brick Mortar Ventures

Brick & Mortar Ventures is a venture capital firm founded in 2015 that invests in early-stage startups building technology for the architecture, engineering, construction (AEC) and facilities management industries.

Alumni Ventures

Alumni Ventures (AV) is a venture capital firm that co-invests alongside lead VCs in startups, backing founders with capital and access to a large investor and operator community.

Both backed · 1
$100K – $10M
Sierra Ventures

Sierra Ventures is an early-stage venture capital firm that invests in first-principles founders, backing companies from inception through Series A across AI infrastructure, applied/vertical AI, deep tech, and physical/embodied AI.

Both backed · 1
$10M
Shasta Ventures

Shasta Ventures is an early-stage venture capital firm that partners with founders building software, AI, and deep technology companies, providing capital, insight, and operating experience.

Both backed · 1
$250K – $6M
Origin Ventures

Origin Ventures is an early-stage venture capital firm backing founders building companies in the artificial intelligence economy, focusing on infrastructure, software, applications, services, and marketplaces that transform productivity and automation.

Both backed · 1
$500K – $5M
Paladin Capital Group

Paladin Capital Group invests in early stage and growth companies developing cyber, AI and deep technologies that address security and resilience needs for commercial and government customers.

Both backed · 1
$100K – $5M
ForgePoint Capital

ForgePoint Capital is a thesis-driven venture firm investing in early-stage companies in cybersecurity, AI, and infrastructure software.

Both backed · 1
$5M – $50M
Ironspring Venture

Ironspring Ventures is a venture capital firm focused on the digital transformation of legacy industrial sectors, backing startups across construction, supply chain, logistics, manufacturing, and energy.

Both backed · 1
$1M – $4M
29 more co-investors

Baird CapitalTensility Venture PartnersL'ATTITUDE VenturesDebut CapitalAndreessen HorowitzLightspeed Venture PartnersRedpoint VenturesFounder CollectiveNorwest Venture PartnersBattery VenturesNextView VenturesQED InvestorsRed Swan VenturesWingGeneral AtlanticNextGen Venture PartnersRelay VenturesAmity VenturesAV8 VenturesBroadhaven Capital PartnersTwo Bear CapitalNorthwestern Mutual AcceleratorDreamit VenturesSozo VenturesKaya VenturesSante VenturesTexas HALO FundThe Riverside CompanyFasterCapital

Firms observed investing alongside S3 Ventures, from public investor directories. Shared companies are the overlap with S3 Ventures's recorded portfolio.

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