/Investor DB

Sante Ventures

Crossover fundActively deployingventure arm of Sante

Austin · Seed–Series A · 36 people tracked

Also known as SHVMS, LLC

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Investment thesis

Santé invests at the intersection of healthcare and technology innovation, seeking visionary entrepreneurs and new ideas that can improve patient outcomes through advances in biology, medicine, and information. Its venture arm, Santé Ventures, targets private healthcare companies with a focus on biotech, medtech, and healthtech. Its public-markets arm, Santé Capital, uses a proprietary MindRank platform built on big data, machine learning, and natural language processing to identify mispriced publicly traded securities and generate risk-adjusted returns through a systematic liquid hedge fund strategy.

Source: firm website, verified Sep 29, 2026.

Stage
Seed–Series A
Check
$2M – $6M
HQ
Austin, Texas, US
Leads rounds
Leads
Instruments
Equity
Founded
2006
Last 12 months
5 investments
AUM
$1B
VC funds
9
Tracked investments
19

Team · 36 people

from the firm's website & curated & public directories
Alana Horowitz· Senior Associatein
Allie Knauer· Venture Fellow
Brooke Jones· Head of Capital Formation
Charlene Tang· Venture Fellow
Ian Alrahwan· AI Engineer
Jake Rogers· Head of Operationsin
Jeff Crawford· Head of Finance
Kyle Schroeder· Senior Analystin
Laura McMillian· Office Manager
Mateo Vargas· Senior Associatein
Michael Hoffman· Senior Advisor
Ryan Hall· Associatein
Shannon Czimskey· Senior Financial Accountantin

What they invest in

from 13 of 19 portfolio companies

Healthtech ×12Digital Health ×7AI & Machine Learning ×6Medical Devices ×5Biotech ×4Data & Infrastructure ×2Cleantech ×1Climate Tech ×1

HQs:United States×11

Investments · 19 tracked

founders shown can be your intro path

By year:2026 · 32025 · 22023 · 22022 · 22021 · 22020 · 12017 · 12016 · 12013 · 12010 · 12009 · 218 dated

Aimbientaimbient.comin𝕏Series A · May 2023 · $15M

Aimbient builds an ambient AI platform for procedural medicine that automatically captures clinical cases and generates actionable intelligence for healthcare teams to improve patient care and operational outcomes.

AI & Machine LearningHealthtechMedical DevicesNew York, US

Co-investorsUS Venture Partners

BAROnova, Inc.baronova.cominSeries C · Feb 2013 · $27M

Non-surgical, non-pharmacologic devices to induce weight loss

Co-investorsDelos CapitalLongitude CapitalArboretum VenturesHighland Capital Partners

BeeKeeperAIbeekeeperai.comin𝕏Series A · Jun 2023 · $12.1M

BeeKeeperAI enables healthcare AI developers and researchers to access diverse, real-world clinical data while keeping it secure within private cloud infrastructure.

AI & Machine LearningCybersecurityData & InfrastructureDigital HealthHealthtech

Co-investorsAIX Ventures

Clairityclairitytech.comSeries B · Nov 2025 · $43M

Clairity develops direct air capture and mineralization technology to remove carbon dioxide from the atmosphere.

CleantechClimate TechDeep TechHealthtechSouthern Nevada, US

Glen Meyerowitz(Founder)

BoardJoe Cunningham(Director)Kevin Lalande(Executive Officer, Director)

Co-investorsInitialized CapitalLowercarbon CapitalSante Health Ventures

Claret Medicalclaretmedical.comOct 2017

HealthtechSanta Rosa, US

Fred Khosravi(Director)Tony Fields(Executive Officer)

BoardJames Eadie(Director)Azin Parhizgar(Executive Officer, Director)inHenry A. Plain(Director)Leo Nelson Hopkins(Director)

Co-investors415 CapitalLightstone VenturesEaston CapitalMorgenthaler

Endostimendostim.comin𝕏Series B · Jul 2010 · $6M

EndoStim develops a neurostimulation medical device system for treating drug-resistant gastroesophageal reflux disease (GERD) by restoring esophageal function while preserving normal anatomy.

BiotechHealthtechMedical DevicesSt. Louis, US

Eric Goorno(Chief Executive Officer)Greg Wilson(Chief Financial Officer)Stephen Attwood, MD(Surgical Director)Virender Sharma, MD(Chief Medical Officer)Hazim Ansari(Chief Legal Counsel)Bevil J. Hogg(Executive Officer, Director)

Co-investorsRelevance Ventures

Kela Healthkelahealth.comin𝕏Seed · Oct 2020 · $3M

KelaHealth develops data-driven solutions that apply insights from millions of patient records to personalize and improve medical decision-making.

AI & Machine LearningData & InfrastructureDigital HealthHealthtechMedical DevicesSan Francisco, US

Bora Chang(Executive Officer, Director)

BoardDennis McWilliams(Director)

Co-investorsBlue Hour VenturesIntuitive VenturesNC IDEANueterra CapitalTechstars

Lumos Pharmalumos-pharma.comin𝕏Series A · Apr 2016 · $14M

Lumos Pharma is a clinical-stage biopharmaceutical company developing therapies for rare diseases, with a lead candidate targeting Pediatric Growth Hormone Deficiency.

BiotechHealthtechAustin, US

Richard John Hawkins(Executive Officer, Director)John C. McKew(President and Chief Scientific Officer)inPisit "Duke" Pitukcheewanont(Chief Medical Officer)inLori Lawley(Chief Financial Officer)inBrad Powers(Chief Compliance Officer and General Counsel)inCampbell Murray(Executive Chairman)in

Co-investorsNew Enterprise Associates (NEA)Clarus VenturesDeerfield Management CompanySante Health VenturesWellcome Trust

OutcomesAIoutcomes.aiin𝕏Seed · Oct 2025 · $10M

OutcomesAI combines AI voice agents with licensed nurses to deliver scalable, high-quality care across hospitals, virtual care, and specialty programs.

AI & Machine LearningDigital HealthHealthtech

Kuldeep Singh Rajput(Founder)

Co-investorsHeadwater Ventures

RapidPulserapidpulsemed.comSeries A · Jun 2021 · $15M

RapidPulse Medical is an investor relations page showcasing multiple healthcare-focused investment firms and incubators that back medical device and healthcare technology companies.

BiotechDigital HealthHealthtechMedical Devices

Co-investorsBroadview VenturesEpidarex CapitalFlorida Opportunity FundHatteras Venture PartnersS3 Ventures

Reimagine Carereimaginecare.cominSeries A · Jan 2022 · $25M

Reimagine Care partners with cancer providers and health systems to deliver virtual oncology care combining AI-powered support, clinical expertise, and digital monitoring to manage symptoms, reduce emergency visits, and improve patient outcomes outside the clinic setting.

AI & Machine LearningDigital HealthHealthtechNashville, US

Dan Nardi(Mr. Nardi is the CEO and a director of the Issuer)Keith Figlioli(Director)Feby Abraham(Director)Chris Stenzel(Director)

BoardDouglas French(Director)Harlan Levine(Director)in

Co-investorsCU Healthcare Innovation FundFirst Trust Capital PartnersMartin VenturesMcKesson VenturesOncology VenturesLRVHealth

Reprieve Cardiovascularreprievecardio.com

Reprieve Cardiovascular develops a decongestion management system that uses real-time patient data to guide and personalize diuretic therapy for fluid removal in heart failure patients.

Digital HealthHealthtechMedical DevicesMilford, US

Tony Fields(Executive Officer)Adam Bartnik(Executive Officer)inMark Pacyna(Executive Officer, Director)inJim Dillon(Executive Officer, Director)Hanson S. Gifford III(Director)Gregory W Mann(Executive Officer)

Co-investorsArboretum VenturesLightstone VenturesRex Health VenturesDeerfield Management CompanyGenesis Venture Capital

Sensorium Therapeuticssensorium.bioinSeries A · Oct 2022 · $30M

Sensorium Therapeutics is a clinical-stage biotech company developing novel CNS therapies for anxiety, epilepsy, and cognitive dysfunction using its SensAI platform, which integrates AI, chemistry, and curated natural product data to identify therapeutic patterns from over 50 million biological relationships.

AI & Machine LearningBiotechDigital HealthMedford, US

Jerrold Rosenbaum(Director)inJacob Hooker(Executive Officer, Director)inPranav Tadi(Executive Officer)

BoardRyan Katz(Director)inKevin Lalande(Director)inRichard Simon(Director)

Co-investorsBonaventure Equity, LLCHatteras Venture PartnersIter InvestmentsMission BiocapitalPalo Santo VCRoute 66 Ventures+3 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

beHuman HealthBradoNirogy TherapeuticsRiseHealthSONIRE TherapeuticsTerapio

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Sante Ventures made?
Sante Ventures has 19 tracked investments, including 5 dated in the last 24 months.
What stage does Sante Ventures invest at?
Sante Ventures invests at the Seed, Series A stages.
What is Sante Ventures's typical check size?
Sante Ventures typically writes checks of $2M – $6M.
What sectors does Sante Ventures focus on?
Sante Ventures focuses on Biotech, Digital Health, Healthtech, Medical Devices.
Where is Sante Ventures located?
Sante Ventures is headquartered in Austin, US.
Does Sante Ventures lead rounds?
Yes, Sante Ventures leads investment rounds.

Co-investors · 8

Arboretum Ventures

Arboretum Ventures is a Midwest-based venture capital firm focused on the healthcare industry, investing in early-stage companies across medical devices, life science tools and diagnostics, tech-enabled care delivery, and pharma adjacencies.

$5M – $15M
Lightstone Ventures

Lightstone Ventures is a life sciences venture firm founded in 2012 that invests in biotech and medtech companies, backing founders translating scientific breakthroughs into therapies and medical technologies.

New Enterprise Associates (NEA)

New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.

Both backed · 1
$200K – $40M
S3 Ventures

S3 Ventures is a Texas-founded venture capital firm investing nationwide in business technology and healthcare technology companies. Backed by a single philanthropic limited partner, it emphasizes patient, flexible capital.

Both backed · 1
$500K – $15M
Venrock

Venrock is a venture capital firm investing across technology and healthcare, backing companies in fintech, developer infrastructure, life sciences, therapeutics, semiconductors, and consumer products.

$500K – $10M
Johnson & Johnson Innovation – JJDC

Johnson & Johnson Innovation is the innovation arm of Johnson & Johnson, working to advance life science innovation through early partnerships, incubation via JLABS, venture investing through JJDC, and late-stage partnerships to address global health challenges.

Domain Associates

Domain Associates is a venture capital firm founded in 1985 that invests in life sciences companies. The firm operates as a limited liability company.

$200K – $15M
Abingworth

Abingworth is a life science venture capital firm that backs early-stage biopharma and biotech companies, helping entrepreneurs translate scientific discoveries into new therapeutics.

$15M – $30M

Firms observed investing alongside Sante Ventures, from public investor directories. Shared companies are the overlap with Sante Ventures's recorded portfolio.

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