Austin · Seed–Series A · 40 people tracked
Also known as SHVMS, LLC
Investment thesis
Santé invests at the intersection of healthcare and technology innovation, seeking visionary entrepreneurs and new ideas that can improve patient outcomes through advances in biology, medicine, and information. Its venture arm, Santé Ventures, targets private healthcare companies with a focus on biotech, medtech, and healthtech. Its public-markets arm, Santé Capital, uses a proprietary MindRank platform built on big data, machine learning, and natural language processing to identify mispriced publicly traded securities and generate risk-adjusted returns through a systematic liquid hedge fund strategy.
Source: firm website, verified Aug 25, 2026.
Team · 40 people
from the firm's website & curated & public directoriesWhat they invest in
from 1 of 1 portfolio companiesDigital Health ×1Healthtech ×1Medical Devices ×1
HQs:United States×1
Investments · 1 tracked
founders shown can be your intro pathReprieve Cardiovascular develops a decongestion management system that uses real-time patient data to guide and personalize diuretic therapy for fluid removal in heart failure patients.
Digital HealthHealthtechMedical DevicesMilford, US
Tony Fields(Executive Officer)Adam Bartnik(Executive Officer)Mark Pacyna(Executive Officer, Director)inJim Dillon(Executive Officer, Director)Hanson S. Gifford III(Director)Gregory W Mann(Executive Officer)
Co-investorsArboretum VenturesLightstone VenturesRex Health VenturesDeerfield Management CompanyGenesis Venture Capital
Portfolio news
latest coverage across their companiesReprieve Cardiovascular · massdevice.com · May 7, 2026
Frequently asked questions
- What stage does Sante Ventures invest at?
- Sante Ventures invests at the Seed, Series A stages.
- What is Sante Ventures's typical check size?
- Sante Ventures typically writes checks of $2M – $6M.
- What sectors does Sante Ventures focus on?
- Sante Ventures focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is Sante Ventures located?
- Sante Ventures is headquartered in Austin, US.
- Does Sante Ventures lead rounds?
- Yes, Sante Ventures leads investment rounds.
Co-investors · 8
Arboretum Ventures is a Midwest-based healthcare venture capital firm that invests in early-stage healthcare startups across medical devices, life science tools and diagnostics, tech-enabled care delivery, and pharma adjacencies.
Lightstone Ventures is a life sciences venture firm founded in 2012 that invests in biotech and medtech companies, backing founders translating scientific breakthroughs into therapies and medical technologies.
New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.
Venrock is a venture capital firm investing across technology and healthcare, backing companies in fintech, developer infrastructure, life sciences, therapeutics, semiconductors, and consumer products.
S3 Ventures is a venture capital firm founded in 2005 that invests in technology companies and medical device/health software startups, backed by a single philanthropic limited partner.
Johnson & Johnson Innovation is the innovation arm of Johnson & Johnson, working to advance life science innovation through early partnerships, incubation via JLABS, venture investing through JJDC, and late-stage partnerships to address global health challenges.
Domain Associates is a venture capital firm founded in 1985 that invests in life sciences companies. The firm operates as a limited liability company.
Abingworth is a life science venture capital firm that backs early-stage biopharma and biotech companies, helping entrepreneurs translate scientific discoveries into new therapeutics.
Firms observed investing alongside Sante Ventures, from public investor directories. Shared companies are the overlap with Sante Ventures's recorded portfolio.
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