/Investor DB

Pappas Capital

Venture capital

Research Triangle Park · Seed–Late Stage · 15 people tracked

Also known as A.M. Pappas & Associates, LLC · PAPPAS CAPITAL, LLC

Not to be confused with Pappas Capital (Venture capital · Durham, US)

Find your way into Pappas Capital

1,858 people in our graph share verified history with the Pappas Capital team — schools, employers, funds. One of them is your warm intro.

Atsushi Shimadaunlockedknows William Pay · together at Takeda (overlapped)
knows the team · via Bryan, Garnier & Co
×6knows the team · via Echo Health Ventures
×4knows the team · via C100 Association
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Investment thesis

Pappas Capital focuses on the life sciences, investing in and building companies that develop next-generation products and technologies addressing the full range of human disease. Over more than three decades the firm has backed 100+ companies across the United States, Canada, and Asia, whose products have reached the market to treat conditions such as melanoma, ovarian cancer, and hemophilia. The firm brings hands-on operating and investment expertise, and also runs specialized fund management vehicles including the Chiesi Ventures Fund, Asia Innovation Ventures, AgTech initiatives, and translational medicine programs. It works with both entrepreneurs seeking capital and partners looking to invest.

Source: firm website, verified Sep 26, 2026.

Stage
Seed–Late Stage
Check
$100K – $6M
HQ
Research Triangle Park, North Carolina, US
Instruments
Equity
Founded
1994
AUM
$800M
VC funds
8
Tracked investments
18
IPOs
2
Acquisitions
1

Team · 15 people

from curated & public directories

Founder mafia

2 people who came through Pappas Capital went on to found or lead other companies.

What they invest in

from 15 of 18 portfolio companies

Biotech ×10Healthtech ×8Medical Devices ×3Climate Tech ×2AI & Machine Learning ×1Cleantech ×1Cloud Computing ×1Consumer ×1

HQs:United States×9Germany×1Singapore×1Vietnam×1

Investments · 18 tracked

founders shown can be your intro path

By year:2025 · 12024 · 12022 · 32021 · 12020 · 32018 · 32017 · 214 dated

4D Molecular Therapeutics4dmoleculartherapeutics.cominNASDAQ: FDMTSep 2018 · $90M

4DMT is a late-stage biotechnology company that develops gene delivery systems and genetic therapeutics targeting specific tissue types for various diseases.

BiotechHealthtechEmeryville, US

David Kirn(Executive Officer, Director)inDavid Schaffer(Director)inTheresa Janke(Executive Officer)in

BoardSharon Tetlow(Director)Margi McLoughlin(Director)

Co-investorsAmzak HealthBerkeley CatalystBOLD LongevityChiesi VenturesPappas CapitalPfizer Venture Investments+6 more

Aktis Oncologyaktisoncology.cominNASDAQ: AKTSAug 2022

Aktis Oncology discovers and develops targeted radiopharmaceuticals for treating solid tumors.

BiotechHealthtechMedical DevicesBoston, US

Todd Foley(Co-founder and Chairman)inPatrick Baeuerle(Co-founder & Advisor)inShulamit Ron-Bigger(Executive Officer)inKyle D. Kuvalanka(Chief Financial Officer)inAkos Czibere(Chief Medical Officer)inPaul L. Feldman(Chief Scientific Officer)in

Co-investorsAndreessen HorowitzEcoR1 CapitalMPM BioImpactMRL Ventures FundPappas CapitalRA Capital+5 more

CuraSen Therapeuticscurasen.cominOct 2018✓ verified

CuraSen Therapeutics is a privately funded biopharmaceutical company developing treatments that selectively activate adrenergic receptors in the brain to restore noradrenergic signaling.

BiotechHealthtechSan Carlos, US

Anthony P. Ford(Executive Officer, Director)inBenjamin Potter(Executive Officer)Anthony FordinHenry Skinner(Director)Liam Ratcliffe(Director)in

BoardRon Hunt(Director)in

Co-investorsAlta PartnersLongitude Capitalabrdn plcIntermediate Capital GroupJohnson & Johnson Innovation – JJDCNew Leaf Venture Partners+2 more

Sorriso Pharmaceuticalssorrisopharma.cominDec 2021✓ verified

Sorriso Pharma is a biopharmaceutical company backed by leading venture capital firms specializing in life sciences and healthcare investments.

BiotechHealthtechMedical DevicesSandy, US

Ciara Kennedy, Ph.D.(Executive Officer, Director)Brian Dorsey(Executive Officer)Michael Grey(Director)Mark Chin(Director)Susan Dube(Executive Officer)

BoardEdward Mathers(Director)

Co-investorsNew Enterprise Associates (NEA)NEA Secondary

Amplyxamplyx.comMay 2020

Developing a new class of antifungal medicine to overcome limitations of current therapies.

Co-investorsBioBritGolden SeedsKeiretsu ForumPappas CapitalSofinnova Ventures3x5 Partners+4 more

Avenge Bioavengebio.comJan 2022 · $45M

Biotechnology company developing the LOCOcyte cell-therapy platform for local dosing of immunotherapeutics.

Co-investorsLongitude CapitalPerceptive Xontogeny VentureRock Springs Capital

Reneoreneo.deinDec 2020 · $95M

Reneo is an asset and investment management platform for decarbonizing residential real estate portfolios in Germany.

Climate TechEnterprise SoftwarePropTechGermany, DE

Lennart Börner(Founder & Co-CEO)inAlexander Graubner-Müller(Founder & Co-CEO)in

Co-investorsFoundamentalAbingworthAisling CapitalAmzak HealthEurazeoLakestar+4 more

Reneo Pharmaceuticalsreneopharma.comDec 2020 · $95M

Xoilac TV is a free online football (soccer) live-streaming platform serving fans in Vietnam, offering Full HD match broadcasts of European, Asian, Vietnamese, and international competitions.

ConsumerMedia & EntertainmentSports Tech

Co-investorsAisling CapitalNew Enterprise Associates (NEA)Pappas CapitalRiverVest Venture PartnersAbingworthAmzak Health+2 more

Ribometrixribometrix.com

BiotechGreenville, US

Kevin Weeks(Executive Officer, Director)Katherine Warner(Executive Officer)Joshua Resnick(Director)Michael Solomon(Director)John Gustofson(Director)

BoardMike Dial(Director)in

Co-investorsHatteras Venture PartnersIllumina VenturesM VenturesMC Healthcare VenturesPappas CapitalSV Health Investors+2 more

Rotation Medicalrotationmedical.com

HealthtechPlymouth, US

Thomas Westling(Executive Officer, Director)inMartha Shadan(Executive Officer, Director)Randy Nuernberg(Executive Officer)Craig Van Kampen(Executive Officer)

BoardFouad Azzam(Director)inScott Weiner(Director)in

Co-investorsNew Enterprise Associates (NEA)Pappas CapitalLSP (Life Sciences Partners)

Solusolu.bioin𝕏

Solu provides a cloud-based genomic surveillance platform that analyzes microbial genomes in real-time without requiring coding or configuration.

BiotechCloud ComputingHealthtech

Sam Sihvonen(Founder)in

Co-investorsLifeline VenturesWave Ventures

Solusolutherapeutics.comin𝕏

Solu Therapeutics is a clinical-stage biotech developing a class of antibody therapeutics that link bifunctional small molecules to proprietary effector antibodies (its CyTAC and TicTAC platforms) to reach cell surface targets like GPCRs and ion channels.

BiotechHealthtech

Phil Vickers(CEO / Leadership)inMichael Boretti(Leadership)inBrandon Turunen(Leadership)inSergio Santillana(Leadership)Enda Moran(Leadership)inKelly Honohan(Leadership)in

Co-investorsAstellas Venture Management LLCLongwood Fund

Us2us2.aiin𝕏Apr 2022

Us2.ai provides FDA-cleared AI software that automatically analyzes echocardiograms and generates structured clinical reports in real time.

AI & Machine LearningDigital HealthHealthtechMedical Devices

Co-investorsEast Post Road VenturesFJ LabsPartech VenturesPeak XV Partners

Velosbiovelosbio.comin𝕏Oct 2018

A biopharmaceutical company developing medicines and vaccines with a focus on clinical research and development for human health.

BiotechSan Diego, US

David Johnson(Executive Officer, Director)Cam Gallagher(Director)Scott L. Glenn(Director)in

Co-investorsChiesi VenturesDecheng CapitalPappas CapitalSofinnova VenturesVedanta CapitalArix Bioscience+2 more

Veraloxveralox.comNov 2024acquired by Cadrenal Therapeutics · Dec 2025 · $200K

Developing novel treatments based on the 12-LOX pathway for immuno-inflammatory diseases.

Co-investorsAlumni VenturesHatteras Venture PartnersPappas CapitalSanofi VenturesAlexandriaGenesys Capital+4 more

VFlowTechvflowtech.cominMay 2025 · $20.5M

VFlowTech develops PowerCube vanadium flow battery energy storage systems for commercial, industrial, grid and distributed generation applications in the renewable energy market.

CleantechClimate TechEnergyHardwareSingapore, SG

Avishek Kumar(CEO)inArjun Bhattarai(CTO)in

Co-investorsEntrepreneur FirstUntroD CapitalWavemaker PartnersAntares Ventures Pte. Ltd.Granite AsiaMOL PLUS+1 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Amplyx PharmaceuticalsOrphoMed

Exits · 3

2 IPOs · 1 acquisitions

4D Molecular TherapeuticsNASDAQ: FDMTAktis OncologyNASDAQ: AKTSVeraloxacq. by Cadrenal Therapeutics

Portfolio news

latest coverage across their companies

Public market activity · per SEC filings

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Disclosed stake · filed Feb 2016

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Disclosed stake · filed Mar 2014

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Disclosed stake · filed Nov 2012

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Disclosed stake · filed Jul 2011

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Disclosed stake · filed May 2011

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Disclosed stake · filed Aug 2010

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Disclosed stake · filed Mar 2006

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Disclosed stake · filed Dec 2005

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14 insider ownership filings (Forms 3/4/5)

From the firm's own SEC EDGAR filings — stakes and insider roles in public companies, typically portfolio companies after an IPO. Not a portfolio list published by the firm.

Frequently asked questions

How many investments has Pappas Capital made?
Pappas Capital has 18 tracked investments, 3 of which have exited, including 2 dated in the last 24 months.
What stage does Pappas Capital invest at?
Pappas Capital invests at the Seed, Series A, Series B, Series C, Late Stage stages.
What is Pappas Capital's typical check size?
Pappas Capital typically writes checks of $100K – $6M.
What sectors does Pappas Capital focus on?
Pappas Capital focuses on AgTech, Biotech, Healthtech, Medical Devices.
Where is Pappas Capital located?
Pappas Capital is headquartered in Research Triangle Park, US.

Images

Pappas Capital photo

Co-investors · 6

New Enterprise Associates (NEA)

New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.

$200K – $40M
Kleiner Perkins

Kleiner Perkins is a venture capital firm that backs founders across technology and life sciences, from early stage through growth.

$500K – $15M
Canaan Partners

Canaan Partners is a venture capital firm with over 30 years of history, backing companies across technology and healthcare sectors through close, hands-on partnerships with founders.

$500K – $20M
EQT Life Sciences

EQT Life Sciences, formerly LSP, is one of Europe's largest and most experienced life sciences investors, backing companies developing therapeutics, medical devices, diagnostics and healthtech globally. It is part of EQT Group.

$11M – $66M
Avoro Capital Advisors

Avoro Capital Advisors is an investment firm focused on healthcare and life sciences, pursuing scientific breakthroughs that address unmet medical needs.

Amplitude Venture Capital

Amplitude Ventures is a Canadian venture capital firm that creates, builds, and grows precision medicine companies, investing in human health from ideation through patient care.

Firms observed investing alongside Pappas Capital, from public investor directories. Shared companies are the overlap with Pappas Capital's recorded portfolio.

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