Deerfield Management Company — Full Portfolio

Black Diamond Therapeutics develops small-molecule kinase inhibitors targeting families of oncogenic mutations across cancer types, including its lead candidate silevertinib for EGFR-mutant lung cancer and glioblastoma.

EBElizabeth Buck(Chief Scientific Officer)inBrent Hatzis-Schoch(Chief Operating Officer and General Counsel)inSYSergey Yurasov(Chief Medical Officer)inMelanie Morrison(Chief Development Officer)

Co-investorsLALAVLILilly Asia VenturesNENew Enterprise Associates (NEA)NENextech InvestNSNSG VenturesRARA Capital+4 more

Cabaletta Bio is a clinical-stage biotechnology company developing engineered T cell therapies for patients with autoimmune diseases.

BiotechHealthtechRadnor, US

SNSteven Nichtberger(Founder)inDGDan Geffken(Executive Officer)inAnup Marda(Chief Financial Officer)inMark Simon(Director)

BoardBDBrian Daniels(Director)in

Co-investors5A5AM VenturesBABain Capital Life Sciences

Edgewise Therapeutics discovers and develops small molecule medicines targeting muscle proteins to treat neuromuscular and cardiac diseases, including sevasemten for muscular dystrophies and EDG-7500 for cardiomyopathy, leveraging a proprietary drug discovery platform based on muscle physiology and high-throughput functional assays.

BiotechDigital HealthBoulder, US

Kevin Koch(Executive Officer, Director)inARAlan Russell(Director)inBEBadreddin Edris(Director and Co-Founder)inKHKenneth Harrison(Director)

BoardPTPeter Thompson(Director)inJRJonathan Root(Director)in

Co-investorsBOBoulder VenturesFOForesite CapitalOROrbiMedUSUS Venture PartnersVIViking GlobalWEWellington Management+1 more

Editas Medicine develops gene editing medicines using CRISPR/Cas9 and CRISPR/Cas12a technology to treat serious diseases including blood disorders, cardiovascular conditions, and cancer.

BiotechDeep TechMedical DevicesCambridge, US

FZFeng Zhang(Founder)inGCGeorge Church(Scientific Founder, Professor of Genetics, Harvard University and MIT)inKeith Joung(Scientific Founder, Professor of Pathology, Harvard Medical School)inDLDavid Liu(Scientific Founder, Professor of Chemistry and Chemical Biology, Harvard University)inKBKatrine Bosley(Executive Officer, Director)inVMVic Myer(Executive Officer)in

Co-investorsECEcoR1 CapitalGVGV (Google Ventures)SOSofinnova VenturesVIViking GlobalATAtlas VentureFLFlagship Ventures+2 more

Foghorn Therapeutics is a clinical-stage biotech developing chromatin-targeted cancer drugs via its Gene Traffic Control platform, including a candidate co-developed with Eli Lilly.

AGAdrian Gottschalk(President and Chief Executive Officer)

Co-investorsFLFlagship PioneeringXEXeraya CapitalBIBiotechnology Value Fund

GeneDx provides advanced genetic testing and clinical interpretation services to help clinicians diagnose rare and inherited genetic disorders, with AI-driven genomic intelligence that supports patient care decisions and accelerates research and drug discovery.

AI & Machine LearningBiotechDigital HealthHealthtech

KSKatherine Stueland(CEO)in

Co-investorsOAOak HC/FT

Kiniksa is a global biopharmaceutical company that discovers and develops novel therapies for patients with unmet medical needs, with a focus on cardiovascular diseases and related conditions.

BiotechMedical DevicesHamilton

THOMAS W BEETHAM(Executive Officer)inSKSanj K. Patel(Chief Executive Officer and Chairman of the Board)

BoardSTEPHEN R BIGGAR(Director)FELIX J BAKER(Director)G. BRADLY COLE(Director)RICHARD S LEVY(Director)

Co-investorsSOSofinnova VenturesSOSofinnova Venture Partners

Mirum Pharmaceuticals is a biopharmaceutical company that develops and delivers therapies for people living with rare diseases.

BiotechHealthtechSan Diego, US

CPChris Peetz(Co-founder & Chief Executive Officer)inEBEric Bjerkholt(Executive Officer)inPRPeter Radovich(Executive Officer)in

BoardPHPatrick Heron(Director)inMichael Grey(Director)Timothy Walbert(Director)

Co-investorsCHChiesi VenturesFRFrazier Life SciencesLOLongitude CapitalMEMESA VERDE VENTURE PARTNERSNENew Enterprise Associates (NEA)PAPappas Capital+4 more

Pacific Biosciences develops long-read DNA and RNA sequencing platforms and kits for genomics research, including whole genome, targeted, epigenetic, and RNA sequencing applications.

BiotechDeep TechMedical DevicesMenlo Park, US

COChristian O. Henry(Executive Officer, Director)inJeff Eidel(Executive Officer)inSGSusan G. Kim(Executive Officer)inMVMark Van Oene(President and Chief Executive Officer)

BoardWilliam W. Ericson(Director)Hannah A. Valantine(Director)

Co-investorsDADag VenturesKLKleiner PerkinsMAMaverick CapitalMOMohr Davidow VenturesTHThe Blackstone Group

Helicons develops a peptide-based therapeutic platform designed to target intracellular proteins previously considered undruggable by combining the specificity of antibodies with the cell-penetrating properties of small molecules.

AI & Machine LearningBiotechDeep TechMedical Devices

MMMathai Mammen(CEO, President and Chairman)inMMMathai Mammen, M.D., Ph.D.(Chairman, CEO and President)inJohn McGee, Ph.D.(Scientific Co-Founder and Executive Vice President, Head of Platform)

Co-investorsARARCH Venture PartnersCACatalio Capital Management, LPFOForesite CapitalFRFrazier Life SciencesGEGeneral CatalystGVGV (Google Ventures)+9 more

SCYNEXIS is a biopharmaceutical company focused on developing drug therapies for severe rare diseases, including anti-infective and antifungal treatments.

BiotechMedical DevicesDurham, US

YJYves J. Ribeill(Executive Officer, Director)inCharles F. Osborne, Jr.(Executive Officer)Brian Schwab(Executive Officer)inDADavid Angulo(President & Chief Executive Officer)inEric Sukenick(General Counsel)Sanjay Subramanian(Chief Financial Officer)

Co-investorsDEDecheng CapitalFOForesite CapitalRARA Capital

Xilio Therapeutics is a clinical-stage biotechnology company developing masked immuno-oncology therapies that use protein engineering to remain inactive until activated by tumor-specific proteases within the tumor microenvironment.

BiotechHealthtechWaltham, US

RRRené Russo(Executive Officer, Director)inJoseph Farmer(Executive Officer)Timothy Clackson(Executive Officer)Christopher Frankenfield(Chief Financial and Operating Officer)inKLKatarina Luptakova(Chief Medical Officer)inPaul Clancy(Director)

Co-investorsBABain Capital Life SciencesBABay City CapitalF-F-Prime CapitalM M VenturesMRMRL Ventures FundRARA Capital+9 more

MMI develops miniaturized robotic surgical instruments and platforms to enable surgeons to perform complex microsurgery and supermicrosurgery on delicate anatomical structures with greater precision.

HealthtechMedical DevicesRoboticsJacksonville, US

MTMark Toland(Executive Officer, Director)inAndrew Cleeland(Director)JLJustin Lynch(Director)inTheresa Jean Cameron(Director)Caleb Moore(Executive Officer)Augusto Vianna Castello(Director)

Board seatAEAndrew ElBardissi· per SEC Form D

Co-investorsANAndera PartnersBIBioStar CapitalFIFidelity InvestmentsRARA CapitalCOCorewell Health VenturesFOFountain Healthcare Partners

NXT Biomedical is a medical device incubator that develops and spins out startups building clinical medical technologies aimed at addressing unmet needs and reducing healthcare costs.

BiotechHealthtechMedical DevicesIrvine, US

Stanton Rowe(CEO)inDon Bobo(Director)

BoardKadhiresan V Kadir(Director)Steven Hochberg(Director)Andrew Cleeland(Director)

Board seatAEAndrew ElBardissi· per SEC Form D

Alo Solutions provides capital investment and practice transition support services for independent physicians seeking to expand their practices, plan for succession, or transition their patient panels.

Digital HealthEnterprise SoftwareFintechHealthtechSaaSRaleigh, US

MEMatt Eirich(CEO)inACAngie Cain(Chief Administrative Officer)inLynn Gordon(Chief Legal & Compliance Officer)in

Pleno develops a genomic testing instrument platform designed to make multiomics testing faster, lower-cost, and higher-plex than existing methods like NGS, PCR, and microarrays.

BiotechHardwareHealthtech

Co-investorsFOForesite CapitalMEMedical Excellence Capital

SpectraWAVE develops optical and computational imaging technologies to diagnose and guide treatment decisions for patients with coronary artery disease and cardiovascular disease.

AI & Machine LearningDeep TechHealthtechMedical DevicesBedford, US

ENEman Namati(President & CEO)inGTGuillermo Tearney(Founder; Professor of Pathology, Massachusetts General Hospital)GSGregg Stone(Founder; Professor of Medicine, Mount Sinai Heart Health System)JMJames Muller(Founder; Cardiologist, Brigham and Women's Hospital)inJeffrey O'Donnell(Founder; Managing General Partner, Runway Healthcare)VWVivek Walimbe(Chief Operating Officer)in

Co-investorsLULumira VenturesS3S3 VenturesSVSV Health InvestorsJOJohnson & Johnson Innovation – JJDC

HealthtechCarlsbad, US

CSChristoph Scharf(Director)inRandy Werneth(Executive Officer, Director)Graydon Beatty(Executive Officer)inVBVince Burgess(Director)inJohn Dahldorf(Executive Officer)

BoardAditya Puri(Director)

Board seatAEAndrew ElBardissi· per SEC Form D

Co-investorsADAdvent Life SciencesOROrbiMedXEXeraya CapitalFOFormation GroupGEGE VenturesINIndex Ventures

Adela develops blood-based tests for cancer detection using epigenetics and liquid biopsy technology, aimed at helping patients and clinicians detect and act on cancer earlier.

BiotechDigital HealthHealthtechMedical DevicesFoster City, US

DDDaniel Diniz De Carvalho(Executive Officer, Promoter)SBScott Bratman(Executive Officer, Director)inAHAnne-Renee Hartman(Founder)inAWAlan Williams(Executive Officer)inLALisa Alderson(Executive Officer, Director)inPriscilla Huang(Executive Officer)in

Board seatAEAndrew ElBardissi· per SEC Form D

Co-investorsDEDecheng CapitalF-F-Prime CapitalOROrbiMedMEMenlo Ventures

Appello Pharma is a biopharmaceutical company focused on drug discovery and development for neurological and metabolic diseases.

BiotechDigital HealthHealthtechMedical DevicesNashville, US

Dr. Laden(Co-founder)Christopher Rand(Executive Officer)Vaughn Bryson(Director)Jeff P. Conn(Director)

BoardWilliam Slattery(Director)HFHowie Furst(Director)in

Board seatHFHoward Furst· per SEC Form D · $13.5M raise · filed Jan 2022

Co-investorsMOMountain Group CapitalRERelevance Ventures

Ascertain provides an agentic AI platform that automates healthcare administrative work such as prior authorizations, referrals, eligibility checks, and care coordination by integrating with existing systems and embedding human review.

AI & Machine LearningDigital HealthHealthtechNew York, US

MMMark Michalski(Executive Officer, Director)inMarc Berger(Executive Officer)Gregg Fergus(Executive Officer, Director)Laurence Kraemer(Executive Officer)Carlos Dedesma(Executive Officer)Courtney Marcin(Director)

Board seatMAMoses AdubiJHJulian Harris· per SEC Form D

Co-investorsAEAegis Ventures

BiotechSan Francisco, US

MPMatthew Patterson(Executive Officer, Director)in

BoardJSJonathan Silverstein(Director)inSSSteve Squinto(Director)inKPKush Parmar(Director)inThomas Woiwode(Director)

Board seatJLJonathan Leff· per SEC Form D

Co-investorsASAsset Management CompanyHEHercules Capital, Inc.RARA CapitalVEvenBio Partners5A5AM VenturesOROrbiMed+1 more

Aurion Biotech develops regenerative cell therapies for ophthalmology, focused on treating blindness and vision loss from corneal endothelial disease.

BiotechHealthtechMedical DevicesSeattle, US

DAVID ROSTOV(Executive Officer)inGREG KUNST(Executive Officer, Director)PATRICK LALLY(Director)JEANNETTE BANKES(Director)CHRISTINE MCCAULEY(Director)ARNAUD LACOSTE(Executive Officer)

Board seatAEAndrew ElBardissi· per SEC Form D

Co-investorsVIVisionary VenturesFLFlying L Partners

Axon Therapies develops the SAVM procedure, an implant-free catheter-based ablation therapy that targets the right greater splanchnic nerve to reduce overactive sympathetic nerve activity in patients with heart failure with preserved ejection fraction (HFpEF).

HealthtechMedical DevicesNew York, US

HRHoward R. Levin(Executive Officer, Director)Mark Gelfand(Executive Officer)Zoar Engelman, PhD(President & CEO)Chad Hoskins(President & Chief Executive Officer)

BoardPLPaul LaViolette(Director)in

Board seatAEAndrew ElBardissi· per SEC Form D · $15M raise · filed Feb 2019

Co-investorsSTStar51 CapitalACAction Potential Venture Capital Ltd.EAEarlybird Venture CapitalSVSV Health Investors

Dracen Pharmaceuticals is a private drug developer working at the intersection of cancer metabolism and immuno-oncology, developing glutamine antagonists that inhibit tumor glutamine metabolism and remodel the tumor microenvironment.

BiotechHealthtechBaltimore, US

Robert Wild(Co-founder & Chief Scientific Officer)TMThomas M. Estok(Chief Executive Officer, President and Treasurer)Drew Pardoll, M.D., Ph.D.(Director)

BoardRobert Jackson(Director)

Board seatJLJonathan Leff· per SEC Form D

Co-investorsBIBiotech Investments S.R.OI&i&i Biotech FundOUOUP (Osage University Partners)SOSofinnova Ventures

Element Science is a medical technology company that develops the Jewel, an FDA-approved adhesive-based wearable cardioverter defibrillator designed to protect patients at risk of sudden cardiac arrest.

AI & Machine LearningDigital HealthHardwareHealthtechMedical DevicesSan Francisco, US

UNUday N. Kumar(Executive Officer, Director)inUKUday Kumar(Founder)in

BoardRussell Hirsch(Director)NENeil Exter(Director)inKYKrishna Yeshwant(Director)inWilliam H. Kucheman(Director)

Board seatAEAndrew ElBardissi· per SEC Form D · $145.6M raise · filed Mar 2020

Co-investorsGVGV (Google Ventures)THThird Rock VenturesQIQiming Venture Partners

Clinical-stage biotech developing next-generation polyene antifungals for life-threatening invasive fungal infections.

BiotechNew York, US

Kieren Marr(Executive Officer, Director)

BoardJim Flynn(Director)MHMartin Heidecker(Director)in

Board seatJLJonathan Leff· per SEC Form D

Co-investorsAMAMR Action FundILIllinois Ventures

Incardatherapeutics develops drug therapies for treating atrial fibrillation using synergistic combinations of anti-arrhythmic agents, with delivery platforms designed for both hospital and at-home settings.

BiotechDigital HealthMedical DevicesBrisbane, US

CACarlos A. Schuler(Executive Officer, Director)inJSJohn S. Patton(Executive Officer, Director)inRangachari Narasimhan(Executive Officer, Director)GCGrace Colon(Executive Officer, Director)inMiller Samantha(Executive Officer)

BoardMcCarthy Reenie(Director)

Board seatAEAndrew ElBardissi· per SEC Form D

Co-investorsASAsset Management CompanyHEHealthCapSOSofinnova Ventures

BiotechNew York, US

Nader Halim(Executive Officer, Director)Althea Stillman(Executive Officer, Director)

BoardDGDavid Greenwald(Director)in

Board seatJLJonathan Leff· per SEC Form D

Co-investorsBIBioAdvance

NeoChord develops a medical device system for beating heart mitral valve repair in patients with mitral valve regurgitation.

Advanced ManufacturingHealthtechMedical DevicesMaple Grove, US

TBTodd Berg(Executive Officer, Director)inDavid H. Chung(Executive Officer, Director)inRNRon Nelson(Executive Officer)in

BoardCTCasey Tansey(Director)Mudit K. Jain(Director)

Board seatAEAndrew ElBardissi· per SEC Form D

Co-investorsBABaird CapitalTRTreo Ventures, LlcUSUS Venture PartnersU.U.S. Venture Partners

Reprieve Cardiovascular develops a decongestion management system that uses real-time patient data to guide and personalize diuretic therapy for fluid removal in heart failure patients.

Digital HealthHealthtechMedical DevicesMilford, US

TFTony Fields(Executive Officer)ABAdam Bartnik(Executive Officer)inMark Pacyna(Executive Officer, Director)inJim Dillon(Executive Officer, Director)Hanson S. Gifford III(Director)Gregory W Mann(Executive Officer)

Board seatAEAndrew ElBardissi· per SEC Form D

Co-investorsARArboretum VenturesLILightstone VenturesRERex Health VenturesGEGenesis Venture CapitalSASante Ventures

Neomorph develops a molecular glue discovery platform to identify small-molecule medicines that degrade disease-causing proteins through targeted protein degradation.

AI & Machine LearningBiotechDeep TechSan Diego, US

Co-investorsLOLongwood Fund

Actio is a precision medicine company that translates genetic insights into new therapeutics, developing drugs that target the genes underlying both rare diseases and more prevalent conditions.

AI & Machine LearningBiotechDeep Tech

DBDavid Breckenridge(Founder)inDavid B. Goldstein(Founder)

Co-investorsCACanaan PartnersDRDroia VenturesECEcoR1 Capital

Aphage develops AI and sensor technologies to identify, track, and classify physical threats across borders, infrastructure, and transportation networks for government and security organizations.

AI & Machine LearningBiotechDefense TechGovTechGaithersburg, IL

Gregory L. Merril(Executive Officer, Director, Promoter)Carl R. Merril(Executive Officer, Director)in

BoardJLJonathan Leff(Director)inEvan Loh(Director)Jana Jensen(Director)Raymond L. Martz(Director)

Co-investorsHAHackensack Meridian Health Bear's DenMAMaryland TEDCOTETEDCOAMAMR Action FundSOSofinnova Ventures

AlpfaMed develops a Pulsed Field Ablation (PFA) technology that uses targeted, heat-free electrical energy to remodel prostate tissue and treat Benign Prostatic Hyperplasia (BPH).

HealthtechMedical DevicesPalo Alto, US

Allan Zingeler(Executive Officer, Director)inMichael Wiley(Executive Officer, Director)inRupa Patel(Executive Officer)

BoardDavid Bonita(Director)Andrew ElBardissi(Director)Michael Hurley(Director)

Annexon is a clinical-stage biopharmaceutical company developing C1q and classical complement pathway inhibitors to treat complement-mediated autoimmune, neurodegenerative, and ophthalmic disorders.

BiotechHealthtechMedical DevicesSo. San Francisco, US

Ben Barres(Scientific Co-Founder)DLDouglas Love(Founder)inMark L Smith(Executive Officer)CMCampbell Murray(Director)inThomas Wiggans(Director)RSRicky Sun(Director)

Co-investorsBABain Capital Life SciencesCOCorrelation VenturesNENew Enterprise Associates (NEA)BLBlackRockBLBlackstone Life SciencesCLClarus Ventures+2 more

PBM Capital is an investment firm that provides funding and operational support to scientists and entrepreneurs, helping them bring products to market and grow their businesses.

BiotechHealthtechBannockburn, US

Brian Kaspar(Executive Officer, Director)James L'Italien(Executive Officer)Andrew F. Knudten(Executive Officer)Sukumar Nagendran(Executive Officer)Thomas Dee(Executive Officer)Sean Nolan(Executive Officer, Director)

Co-investorsFOForesite CapitalPBPBM CapitalRARA CapitalRORoche Venture FundSOSofinnova Ventures

Geoffrey Chaiken(Founder)Matthew Chaiken(Founder)

Co-investors8V8VCB B CapitalBOBoxGroupFRFriedom

Boulevard Bio is a clinical-stage precision immunology company developing multi-specific antibody therapies for B cell-driven autoimmune diseases, with a lead program targeting IgA nephropathy.

BiotechHealthtech

Cohere Health provides a platform aimed at aligning the interests of patients, physicians, and health plans to support care decisions and improve member outcomes.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechSaaSBoston, US

SNSiva Namasivayam(Executive Officer, Director)inRSRobert Shepardson(Executive Officer)inKCKristen Carucci(Executive Officer)inDuncan Reese(Executive Officer)

BoardDavid Barrett(Director)Amir Debourou(Director)

Co-investorsCOCota CapitalFLFlare Capital PartnersLOLongitude CapitalDEDefine VenturesPOPolaris PartnersTETemasek

ConcertoCare provides coordinated in-home and center-based medical, behavioral, and social care for seniors and adults with complex care needs who have Medicare, Medicare Advantage, or Medicare+Medicaid coverage.

Digital HealthHealthtechLongevity

Co-investorsATAtento CapitalOBObvious VenturesSTSteelSky VenturesADAddeparARArboretum VenturesVAVast Ventures+1 more

Cortica provides in-home, in-clinic, and telehealth neurological therapies for children with autism and developmental differences, integrating neurological, biomedical, behavioral, speech-language, and sensorimotor treatments.

Digital HealthHealthtechMedical DevicesSan Diego, US

DSDr. Suzanne Goh(Founder)NHNeil Hattangadi(Co-Founder and Chief Executive Officer)inBEBriana Elvaiah(Executive Officer)inSuzanne Goh-Hattangadi(Founder)Suzanne Goh, MD, BCBA(Co-Founder and Chief Medical Officer)

BoardRDRyan Drant(Director)in

Co-investors.4.406 VenturesAIAIFAPAPERTURE Venture PartnersCVCVS Health VenturesECEcho Health VenturesLOLongitude Capital+6 more

cystetic Medicines is a drug development company creating an inhaled dry-powder therapy based on an FDA-approved antifungal compound to treat cystic fibrosis, targeting the roughly 10% of patients not helped by existing modulators.

BiotechHealthtechMedical DevicesChampaign, US

MARTIN BURKE, MD., PH.D.(Director)DMDr. Martin D. Burke(Co-founder)DMDr. Michael J. Welsh(Co-founder)DJDr. Jeffry Weers(Chief Technology Officer)PWPETER W STEELMAN(Director)inJONATHAN RAMOS(Director)

Co-investorsILIllinois Ventures

Deerfield Catalyst is a medtech incubator that develops medical technology solutions aimed at improving patient outcomes and care delivery.

HealthtechMedical Devices

HLHoward Levin(CEO & CMO)inMGMark Gelfand(Chief Technology Officer)inZEZoar Engelman(Chief Science Officer)inARAdam Rosenwach(Chief Business Officer)inMaybelle Jordan(Chief Strategy Officer)in

Co-investorsSTStar51 Capital

ElevenLabs is an AI research and product company that builds voice generation and audio processing platforms for creating human-like voice interactions with technology.

AI & Machine LearningCreator EconomyEnterprise SoftwareSaaSLondon, GB

MSMati Staniszewski(Founder)inPDPiotr Dabkowski(Co-founder)inHannah C(Founder)MJMateusz Jakub Staniszewski(Co-founder)inMati Staniszewski Piotr Dabkowski(Founder)Piotr Dąbkowski(Founder)

Co-investorsA.A.Capital VenturesALAlkeon InnovationANAndreessen HorowitzANAntiASAspire11BOBond Capital Management+49 more

Eligible provides insurance billing APIs and a billing platform for healthcare businesses, serving both early-stage healthcare startups and large enterprises.

Developer ToolsDigital HealthFintechHealthtechInsurTechNew York City, US

KGKatelyn Gleason(CEO)JSJames Schuler(CTO)inPatrice Krakow

Co-investorsJAJames Beshara FundY Y CombinatorANAndreessen HorowitzANAnvil CapitalATAthena AdvisorsGEGeneral Catalyst+3 more

San Diego protein-sequencing company behind the ProteoCode platform; ceased operations in late 2025.

Co-investorsARARCH Venture PartnersDEDecheng CapitalALAlexandriaGVGV (Google Ventures)NANan Fung Life SciencesNONorthpond Ventures

Excelsior Sciences develops automated chemistry technology for small-molecule discovery and manufacturing, targeting pharmaceutical and materials development.

AI & Machine LearningBiotechDeep Tech

Marty BurkeBartosz GrzybowskiMFMichael Foley(CEO)inJJJana Jensen(COO)in

Co-investorsKHKhosla VenturesSOSofinnova PartnersCOCornucopian Capital ManagementILIllinois Ventures

Frontier is a drug discovery company developing small-molecule covalent drugs aimed at previously undruggable protein targets across the proteome.

AI & Machine LearningBiotechSouth San Francisco, US

CVChris Varma, Ph.D.(Executive Officer, Director)CVChris Varma(Co-founder, Chairman and CEO)inJim Winkler(Executive Officer)JHJohannes Hermann, Ph.D.(Executive Officer)KWKevin Webster(Executive Officer)inGregory Chow(Executive Officer)

Co-investorsBEBerkeley CatalystDCDCVC (Data Collective)DRDroia VenturesFEFelicis VenturesMPMPM BioImpactRARA Capital+2 more

BiotechCambridge, US

Geoff McDonoughy(Executive Officer, Director)Glenn Goddard(Executive Officer)MAMark Angelino(Executive Officer)

BoardJRJason Rhodes(Director)inCSCatherine Stehman-Breen(Director)Anthony Quinn(Director)

Co-investorsATAtlas VentureFOForesite CapitalWEWellington ManagementCACasdin CapitalF-F-Prime CapitalFIFidelity Investments+1 more

Hallux Inc. develops Hallux Subungual Gel (HSG), a physician-administered terbinafine treatment applied directly to the nail bed to treat onychomycosis (fungal nail infection).

BiotechHealthtechMedical DevicesLaguna Hills, US

Hendrik Arend Kroon(Executive Officer)MTMark Taylor(Executive Officer, Director)inJay Birnbaum(Executive Officer, Director)

BoardPSPeter Steelman(Director)inZheng Su(Director)Bryan Sendrowski(Director)

Clinical-stage genetic medicines company using human-derived AAV vectors and nuclease-free gene editing for rare diseases.

BiotechBedford, US

Siyamak Rasty(Executive Officer)Albert Seymour(Executive Officer)

BoardSteven Gillis(Director)ATArthur Tzianabos(Executive Officer, Director)KPKush Parmar(Director)inRichard Gregory(Director)

Co-investors5A5AM VenturesARARCH Venture PartnersOUOUP (Osage University Partners)ALAlexandriaFIFidelity InvestmentsHBHBM Healthcare Investments+5 more

Humanity offers an enterprise employee wellness platform that uses biological age monitoring to help teams improve health and productivity.

Digital HealthHealthtechHR TechLongevityWellness & Fitness

PWPeter Ward(Founder)in

Co-investorsONOne Way VenturesS1s16SCScientia VenturesTRTrueSight VenturesANAndreessen HorowitzJUJump Crypto+3 more

Humanity provides AI-powered employee scheduling and shift-planning software for frontline and enterprise workforces, automating schedule building, demand forecasting, and labor-cost control.

Future of WorkHR TechSaaSBoston, US

PWPeter Ward(Executive Officer, Director)inMichael Geer(Director)

Co-investorsPOPoint NineSASaaS CapitalTETeam Builder VenturesJUJumpstart Nova

Interleukin operates a B2B platform for sourcing and procuring medical products and services, letting registered buyers discover accredited suppliers, request quotes, send purchase orders, and pay on terms in one system.

B2B MarketplacesHealthtechMedical Devices

Co-investorsBUBuko VenturesJAJanus Henderson Investors

IntusCare builds a technology ecosystem for PACE (Programs of All-Inclusive Care for the Elderly) organizations, offering population health, utilization management, and risk adjustment tools to support care delivery, financial performance, and regulatory compliance.

AI & Machine LearningDigital HealthHealthtechProvidence, US

John Robert Felton(Executive Officer, Director)Robbie Felton(Founder)inEvan Jackson(Founder)inARAlex Rothberg(Founder)in

BoardWHWilliam Helman(Director)inGilbert Addo(Director)

Co-investorsBLBlue Star Innovation PartnersEQEqual Opportunity VenturesFEFelicis VenturesGRGreen Egg VenturesJUJumpstart NovaSEService Provider Capital+5 more

Jaguar Gene Therapy develops gene therapy treatments for severe genetic diseases, focusing on AAV-based platform therapies designed to deliver one-time, long-lasting treatments.

BiotechHealthtechMedical DevicesLake Forest, US

JNJoseph NolaninJNJoe Nolan, MBA(Chief Executive Officer)

Co-investorsAIAIFARARCH Venture PartnersJDJDRF T1D FundGOGoldman SachsSASamsung Ventures

Lark provides AI-powered testing infrastructure for engineering teams that can test UIs, APIs, SDKs, and async workflows through natural language tests.

AI & Machine LearningDeveloper ToolsEnterprise SoftwareSan Francisco, US

VDVijit Dhingra(Founder)inJBJack Brown(Founder)in

Co-investorsY Y CombinatorOLOlive Tree CapitalSTSteelSky VenturesALAlpha Intelligence CapitalAPApplied AngelsARArbor Ventures+4 more

Lark develops AI agents that automate manual workflows for wholesale distributors, integrating with their existing ERP systems and learning from each distributor's historical data and team decisions.

Advanced ManufacturingAI & Machine LearningSan Francisco, US

JWJason Wang(CEO)inMWMichael Wang(Co-Founder)in

Co-investorsY Y CombinatorFRFranklin TempletonKIKing River Capital

Lumeris uses AI combined with human-centered design to address the U.S. primary care shortage, co-creating an AI tool called Tom with physicians and patients to deliver Primary Care as a Service.

AI & Machine LearningDigital HealthHealthtechSt. Louis, US

W. Michael Long(Chairman & Chief Executive Officer, Lumeris Group Holdings Corporation)

Co-investorsBLBlue Venture FundsHAHavencrest Capital ManagementKLKleiner PerkinsBLBlueCross BlueShield Venture PartnersSASandbox Industries

Lumos Pharma is a clinical-stage biopharmaceutical company developing therapies for rare diseases, with a lead candidate targeting Pediatric Growth Hormone Deficiency.

BiotechHealthtechAustin, US

Richard John Hawkins(Executive Officer, Director)John C. McKew(President and Chief Scientific Officer)inP"Pisit "Duke" Pitukcheewanont(Chief Medical Officer)inLLLori Lawley(Chief Financial Officer)inBPBrad Powers(Chief Compliance Officer and General Counsel)inCMCampbell Murray(Executive Chairman)in

Co-investorsNENew Enterprise Associates (NEA)RORoche Venture FundCLClarus VenturesSASante Health VenturesSASante VenturesWEWellcome Trust

San Diego clinical-stage biopharma developing non-bile acid FXR agonists for liver and gastrointestinal diseases.

BiotechSan Diego, US

Ronald Evans(Director)Trisha Millican(Executive Officer)Ken Song(Executive Officer, Director)

BoardKBKristina Burow(Director)inRHRichard Heyman(Director)inANAmir Nashat(Director)in

Co-investorsAGage1ECEcoR1 CapitalLALAVLILifeSci Venture PartnersLILilly Asia VenturesNENew Enterprise Associates (NEA)+8 more

myLaurel provides in-home medical care aimed at improving access for high-risk patients, working with clinicians and care teams.

Digital HealthHealthtechNew York, US

Juan Vallarino(Chief Executive Officer)in

Co-investorsACAcumen AmericaBEBeresford VenturesCICity LightFRFrist Cressey VenturesGVGV (Google Ventures)RERevolution+2 more

HealthtechBranford, US

Sofia Noori(Executive Officer, Director)MMMariam Malik(Executive Officer)in

BoardLVLaura Veroneau(Director)Adrienne Rosenthal(Director)

Co-investors.4.406 VenturesOPOptum Ventures

Nuvalent is a biopharmaceutical company focused on structure-based drug discovery and the development of precision oncology therapies.

BiotechHealthtechMedical DevicesCambridge, US

MSMatthew Shair(Director)inHenry Pelish, PhD(Chief Scientific Officer)R. Porter James(Executive Officer, Director)inJames Porter, PhD(Chief Executive Officer)ABAlex Balcom(Chief Financial Officer)inChristopher Turner, MD(Chief Medical Officer)

Co-investorsAVAvoro Capital AdvisorsBABain Capital Life SciencesVIViking GlobalWEWellington Management

Octave is a mental health practice platform that connects licensed therapists with patients seeking in-network mental health care.

Digital HealthHealthtechMental HealthSaaSSan Francisco, US

SASandeep Acharya(Founder, CEO)inDWDavid White(Executive Officer)in

BoardSBSaurabh Bhansali(Director)inEllie Wheeler(Director)Craig Cimini(Director)

Co-investorsFEFelicis VenturesGRGreycroftHEHealthier CapitalNANat TurnerOBObvious VenturesCOCompany Ventures+3 more

Cambridge, US

CQChristophe Queva(Executive Officer)inTheodore Ashburn(Executive Officer, Director)Alon Lazarus(Director)CWCameron Wheeler(Director)in

BoardBMBriggs Morrison(Director)inMitchell Finer(Executive Officer, Director)

Co-investorsASAstellas Venture Management LLCIMIMM Investment JapanCOCowen Healthcare InvestmentsIMIMM InvestmentK2K2 HealthVenturesMPMPM BioImpact+1 more

Teambit analyzes code, meeting time, and interactions to measure and improve the performance of software development teams, delivering objective metrics.

AI & Machine LearningDeveloper ToolsSaaS

PEPaula Enei(Founder)in

Co-investorsGGGG Capital4B4BIO CapitalGEGeneral CatalystMRMRL Ventures FundNONorwest Venture PartnersNONovo Holdings

Practice Fusion provides a cloud-based electronic health record (EHR) platform for medical practices, with integrated medical billing, e-prescribing, and patient engagement tools.

Digital HealthHealthtechSaaSSan Francisco, US

RHRyan Howard(Executive Officer, Director)in

BoardMark Goines(Director)BSBeth Seidenberg(Director)inMichael Harden(Director)Cora Tellez(Director)

Co-investorsBABand of AngelsCACanvas VenturesLOLongitude CapitalWEWestern Technology InvestmentARArtis VenturesFEFelicis Ventures+6 more

Recovery Centers of America provides inpatient and outpatient addiction treatment, including detox, residential care, PHP/IOP outpatient programs, telehealth, and sober living, along with dual diagnosis and mental health care.

Digital HealthHealthtechMental Health

Relation RX is a biotech company focused on discovering novel medicines through an interdisciplinary approach combining expertise from technology, pharma, academia, and venture.

AI & Machine LearningBiotechDeep TechMiami Beach, US

DRDavid Roblin(Chief Executive Officer)inCasey Benjamin Swerner(Executive Officer)inBenjamin Swerner(Founder)Charles Roberts(Founder)Jake Taylor-King(Founder)

BoardJason Pontin(Director)

Co-investorsDCDCVC (Data Collective)HIHitachi VenturesMAMagnetic VenturesRARaptor GroupKHKhosla VenturesNVNVentures

BiotechLexington, US

VMVictoria M. Richon(Executive Officer, Director)in

BoardCameron Wheeler(Director)Jonathan Root(Director)Laurence Lasky(Director)

Co-investorsAVAvego BioScience CapitalOUOUP (Osage University Partners)PEPeregrine VenturesABAbbVieJJJJDCNONovartis Venture Fund+3 more

SentreHeart appears to now redirect to AtriCure, Inc., a medical device company.

BiotechHardwareHealthtechMedical DevicesRedwood City, US

RSRussell Seiber(Executive Officer, Director)inPSPam Simons(Executive Officer)inGreg Fung(Executive Officer)RSRobert Strasser(Executive Officer)in

BoardPYPhil Young(Director)inVictor Tong(Director)

Co-investorsDEDecheng CapitalPRProspect Venture PartnersUSUS Venture PartnersU.U.S. Venture PartnersVIVivo Capital

Brooklyn, US

Marah Lidey(Executive Officer, Director)Naomi Hirabayashi(Executive Officer, Director)

BoardVictoria Song(Director)

Co-investorsCOComcast VenturesLALaunchCapitalFIFidelity InvestmentsOAOaktreeSUSumitomo Corporation

ShineMed pursues a step-by-step commercialization approach to fusion energy, aiming to prove market value at each stage while generating revenue toward the goal of clean, abundant fusion power.

CleantechDeep TechEnergyHealthtechJanesville, US

Gregory Richard Piefer(Executive Officer, Director)Katrina Pitas(Executive Officer)Darin Janecek(Executive Officer)Anton Asmuth(Executive Officer, Director)James Costedio(Executive Officer)David A. Weissburg(Executive Officer, Director, Promoter)in

Co-investorsVEVenture ManagementWIWisconsin Investment PartnersBABaillie GiffordKOKoch Disruptive Technologies

BiotechColumbus, US

Alex DiNello(Executive Officer)

Somatus provides value-based, integrated kidney care and a congestive heart failure management solution for patients, providers, and health plan partners.

Digital HealthHealthtechMclean, US

IOIkenna Okezie(Executive Officer, Director)inAlexander Houlday(Executive Officer)inStacey Queen-Pyndell(Executive Officer)LRLarry Renfro(Interim President & CEO)

BoardAnna Haghgooie(Director)AWAnthony Welters(Director)

Co-investorsFLFlare Capital PartnersOPOptum VenturesHEHealthQuest CapitalBLBlue Venture FundsDEDefy PartnersLOLongitude Capital+7 more

Soon is a portfolio management platform that automates buying and selling of assets across multiple exchanges using strategies like dollar-cost averaging and tax-loss harvesting.

Crypto & Web3FintechSalt Lake City, US

MSMichael Shattuck(Founder)inAaron BylundChris Lovato

Co-investorsIDIdeashipSOSoma CapitalY Y CombinatorDRDragon CapitalFAFalls FintechFIFidelity Investments+2 more

Strata Oncology develops precision oncology biomarkers and predictive diagnostic tools for cancer treatment, including treatment response scores for antibody-drug conjugates (ADCs) and an Immunotherapy Response Score for anti-PD-1/PD-L1 therapies.

AI & Machine LearningBiotechDigital HealthMedical DevicesAnn Arbor, US

Daniel Rhodes(Executive Officer, Director)Dan Rhodes(Founder)inScott Tomlins(Founder)inMatthew Martin(Executive Officer)Jeffrey Williams(Executive Officer, Director)

BoardCOChristopher O'Donnell(Director)in

Co-investorsARArboretum VenturesBABaird CapitalMEMerck Global Health Innovation FundMSMSD Global Health Innovation FundPFPfizer Venture InvestmentsWEWellington Management+1 more

Synthekine is a clinical-stage biotechnology company using protein engineering platforms to develop cytokine-based immunotherapies designed to preserve therapeutic efficacy while avoiding toxicities linked to cytokine pleiotropy.

BiotechHealthtech

K. Christopher Garcia(Founder)SMSusan Molineaux(CEO)inMartin Oft(Chief Scientific Officer)inNaiyer Rizvi(Chief Medical Officer)inGregory(Chief Technical Officer)Geoff(Chief Business Officer)

Co-investorsSASamsara BioCapitalTHThe Column GroupBABain Capital Life SciencesCACanaan PartnersRARA CapitalTCTCG Crossover+2 more

Syros Pharmaceuticals is a Massachusetts gene-control biotech developing small molecules that regulate disease gene expression.

BiotechCambridge, US

Nancy Simonian(CEO)Peter Wirth(Director)Mark Alles(Director)Philip Sharp(Director)Richard A. Young(Director)Sue Gail Eckhardt(Director)

Co-investorsAIAisling CapitalARARCH Venture PartnersQUQuan CapitalALAlexandriaALAlly Bridge GroupBABain Capital+11 more

Endologix develops medical devices and therapies for treating vascular disease, focusing on interventions such as EVAR (endovascular aneurysm repair) procedures.

HardwareHealthtechMedical DevicesSanta Rosa, US

MVMichael V. Chobotov(Executive Officer)inSLSHARI L. O'QUINN(Executive Officer)inMichael R. Kramer(Executive Officer)KIMBERLEY ELTING(Executive Officer)CHRISTOPHER CHAVEZ(Executive Officer, Director)VKVIVEK K. JAYARAMAN(Executive Officer)in

Co-investors41415 CapitalKAKaiser Permanente VenturesNENew Enterprise Associates (NEA)SRSR One Capital Management

Vanta provides an automated security and compliance platform that helps companies achieve and maintain certifications such as SOC 2 and ISO 27001 through continuous monitoring, evidence collection, and an AI agent that drafts policies and compliance work.

AI & Machine LearningCybersecurityEnterprise SoftwareSaaSSan Francisco, US

CCChristina Cacioppo(CEO & Founder)inBrittany Rose(Executive Officer)Erik Goldman(Founder)RPRob Picard(Security Lead)inMLMatt Long(Senior Software Engineer)inAlex Marquez-Shaw(Recruiter)

Co-investorsSESequoia CapitalY Y CombinatorGOGoldman SachsACAcrew CapitalATAtlassian VenturesBEBeyond Capital+25 more

Verana Health aggregates de-identified clinical data from a network of over 20,000 physicians in ophthalmology, urology, and neurology to power real-world evidence, clinical trial enablement, and quality reporting for pharmaceutical companies and healthcare providers using AI and machine learning.

AI & Machine LearningData & InfrastructureDigital HealthHealthtechSan Francisco, US

Mark Blumenkranz, MD(Co-Founder, Verana Health and Lagunita Biosciences)SJSujay Jadhav(Chief Executive Officer)in

Co-investorsNONovo HoldingsBRBreyer CapitalGVGV (Google Ventures)MEMerck Global Health Innovation FundMSMSD Global Health Innovation FundNANat Turner+7 more

HealthtechMountain View, US

KBKenneth Binmoeller, M.D.(Executive Officer, Director)inGreg Patterson(Executive Officer, Director)

BoardA. Barr Dolan(Director)Eric Sillman(Director)Anthony Natale, M.D.(Director)Avi Kometz(Director)

Co-investorsAPAPERTURE Venture PartnersATATEL VenturesTHThird Point VenturesASAscent Biomedical VenturesTHThird PointWEWestern Technology Investment