Deerfield Management Company — Full Portfolio

Alo is a physician enablement platform offering practice management, financial strategy, and value-based care services to independent physicians managing the business of their practices.

Digital HealthHealthtechSaaS

Matt Eirich(CEO)

Pleno develops a genomic testing instrument platform designed to make multiomics testing faster, lower-cost, and higher-plex than existing methods like NGS, PCR, and microarrays.

BiotechHardwareHealthtech

Co-investorsForesite CapitalMedical Excellence Capital

SpectraWAVE develops optical and computational imaging technologies to diagnose and guide treatment decisions for patients with coronary artery disease and cardiovascular disease.

AI & Machine LearningDeep TechHealthtechMedical DevicesBedford, US

Eman Namati(President & CEO)Guillermo Tearney(Founder; Professor of Pathology, Massachusetts General Hospital)Gregg Stone(Founder; Professor of Medicine, Mount Sinai Heart Health System)James Muller(Founder; Cardiologist, Brigham and Women's Hospital)Jeffrey O'Donnell(Founder; Managing General Partner, Runway Healthcare)Vivek Walimbe(Chief Operating Officer)

Co-investorsLumira VenturesS3 VenturesSV Health InvestorsJohnson & Johnson Innovation – JJDC

HealthtechCarlsbad, US

Christoph Scharf(Director)inRandy Werneth(Executive Officer, Director)Graydon Beatty(Executive Officer)inVince Burgess(Director)John Dahldorf(Executive Officer)

BoardAditya Puri(Director)

Board seatAndrew ElBardissi· per SEC Form D

Co-investorsAdvent Life SciencesOrbiMedGE VenturesIndex Ventures

Adela develops blood-based diagnostic tests that analyze cell-free DNA using whole methylome analysis to detect and monitor cancer.

BiotechDigital HealthHealthtechFoster City, US

Daniel Diniz De Carvalho(Executive Officer, Promoter)Scott Bratman(Executive Officer, Director)Anne-Renee Hartman(Founder)Alan Williams(Executive Officer)Lisa Alderson(Executive Officer, Director)Priscilla Huang(Executive Officer)

Board seatAndrew ElBardissi· per SEC Form D

Co-investorsDecheng CapitalF-Prime CapitalOrbiMedMenlo Ventures

Appello Pharma is a biopharmaceutical company focused on drug discovery and development for neurological and metabolic diseases.

BiotechDigital HealthHealthtechMedical DevicesNashville, US

Dr. Laden(Co-founder)Christopher Rand(Executive Officer)Vaughn Bryson(Director)Jeff P. Conn(Director)

BoardWilliam Slattery(Director)Howie Furst(Director)in

Board seatHoward Furst· per SEC Form D · $13.5M raise · filed Jan 2022

Co-investorsMountain Group CapitalRelevance Ventures

BiotechLanghorne, US

Donald Wetherhold(Executive Officer)Michael Rohlfs(Executive Officer)David Furniss(Executive Officer)Robert Williford(Executive Officer)

BoardLawrence Glassmann(Director)James Evans(Director)

Board seatJonathan Leff· per SEC Form D · $84M raise · filed Jan 2016

BiotechSan Francisco, US

Matthew Patterson(Executive Officer, Director)

BoardJonathan Silverstein(Director)inSteve Squinto(Director)inKush Parmar(Director)Thomas Woiwode(Director)

Board seatJonathan Leff· per SEC Form D · filed Sep 2015

Co-investorsAsset Management CompanyRA CapitalvenBio PartnersOrbiMedVenrock

Aurion Biotech develops regenerative cell therapies for ophthalmology, focused on treating blindness and vision loss from corneal endothelial disease.

BiotechHealthtechMedical DevicesSeattle, US

DAVID ROSTOV(Executive Officer)GREG KUNST(Executive Officer, Director)PATRICK LALLY(Director)JEANNETTE BANKES(Director)CHRISTINE MCCAULEY(Director)ARNAUD LACOSTE(Executive Officer)

Board seatAndrew ElBardissi· per SEC Form D · $26.1M raise · filed Apr 2022

Co-investorsVisionary VenturesFlying L Partners

Axon Therapies develops the SAVM procedure, an implant-free catheter-based ablation therapy that targets the right greater splanchnic nerve to reduce overactive sympathetic nerve activity in patients with heart failure with preserved ejection fraction (HFpEF).

HealthtechMedical DevicesNew York, US

Howard R. Levin(Executive Officer, Director)Mark Gelfand(Executive Officer)

BoardPaul LaViolette(Director)in

Board seatAndrew ElBardissi· per SEC Form D · $15M raise · filed Feb 2019

Co-investorsSV Health Investors

HealthtechMaple Grove, US

Michael Brenzel(Executive Officer)Paul Buckman(Executive Officer)Kent Lind(Executive Officer)John Feriancek(Executive Officer)Paul Hindrichs(Executive Officer)David Blue(Executive Officer)

Board seatAndrew ElBardissi· per SEC Form D · $5M raise · filed Jan 2019

Dracen Pharmaceuticals is a private drug developer working at the intersection of cancer metabolism and immuno-oncology, developing glutamine antagonists that inhibit tumor glutamine metabolism and remodel the tumor microenvironment.

BiotechHealthtechBaltimore, US

Robert Wild(Co-founder & Chief Scientific Officer)Thomas M. Estok(Chief Executive Officer, President and Treasurer)Drew Pardoll, M.D., Ph.D.(Director)

BoardRobert Jackson(Director)

Board seatJonathan Leff· per SEC Form D · $40.5M raise · filed Jan 2018

Co-investorsBiotech Investments S.R.OOUP (Osage University Partners)

Jewel is a wearable patch cardioverter defibrillator designed to provide continuous protection from sudden cardiac arrest, using machine learning to minimize false alarms while requiring no daily maintenance for up to a week.

AI & Machine LearningHealthtechMedical DevicesSan Francisco, US

Uday N. Kumar(Executive Officer, Director)

BoardRussell Hirsch(Director)Neil Exter(Director)inKrishna Yeshwant(Director)inWilliam H. Kucheman(Director)William Kucheman(Director)

Board seatAndrew ElBardissi· per SEC Form D · $145.6M raise · filed Mar 2020

Co-investorsThird Rock VenturesGV (Google Ventures)

Clinical-stage biotech developing next-generation polyene antifungals for life-threatening invasive fungal infections.

BiotechNew York, US

Kieren Marr(Executive Officer, Director)

BoardJim Flynn(Director)Martin Heidecker(Director)in

Board seatJonathan Leff· per SEC Form D · $83.8M raise · filed Jun 2024

Co-investorsAMR Action FundIllinois Ventures

New York, US

Kathryne Cooper(Director)Ronald Mitchell(Executive Officer, Director)Jonathan Ramos(Executive Officer)

BoardMichael Farrell(Executive Officer)in

Board seatBharath GanesanJulian Harris· per SEC Form D · $11M raise · filed Jul 2022

Incardatherapeutics develops drug therapies for treating atrial fibrillation using synergistic combinations of anti-arrhythmic agents, with delivery platforms designed for both hospital and at-home settings.

BiotechDigital HealthMedical DevicesBrisbane, US

Rangachari Narasimhan(Executive Officer, Director)Grace Colon(Executive Officer, Director)Miller Samantha(Executive Officer)Carlos A. Schuler(Executive Officer, Director)John S. Patton(Executive Officer, Director)

BoardMcCarthy Reenie(Director)

Board seatAndrew ElBardissi· per SEC Form D · $50M raise · filed Oct 2020

Co-investorsAsset Management CompanyHealthCapSofinnova Ventures

BiotechNew York, US

Nader Halim(Executive Officer, Director)Althea Stillman(Executive Officer, Director)

BoardDavid Greenwald(Director)in

Board seatJonathan Leff· per SEC Form D · $40M raise · filed Aug 2022

Co-investorsBioAdvance

BiotechIowa City, US

Steven Richard Mickelsen(Executive Officer, Director, Promoter)Raju Viswanathan(Executive Officer)David Jacques(Executive Officer)Allan Zingeler(Executive Officer, Director)

BoardDavid Booth(Director)Howard Dittrich(Director)

Board seatAndrew ElBardissi· per SEC Form D · $12M raise · filed Aug 2018

Co-investorsCadence Healthcare Ventures

MMI develops the Symani Surgical System, a robotic platform with NanoWrist instruments designed for microsurgery and supermicrosurgery, enabling surgeons to perform delicate procedures such as dissection and anastomosis.

HealthtechMedical DevicesRoboticsJacksonville, US

Mark Toland(Executive Officer, Director)Andrew Cleeland(Director)Justin Lynch(Director)Theresa Jean Cameron(Director)Caleb Moore(Executive Officer)Augusto Vianna Castello(Director)

Board seatAndrew ElBardissi· per SEC Form D · $110M raise · filed Mar 2024

Co-investorsAndera PartnersCorewell Health VenturesFountain Healthcare Partners

NeoChord develops a medical device system for beating heart mitral valve repair in patients with mitral valve regurgitation.

Advanced ManufacturingHealthtechMedical DevicesMaple Grove, US

Todd Berg(Executive Officer, Director)David H. Chung(Executive Officer, Director)Ron Nelson(Executive Officer)

BoardCasey Tansey(Director)Mudit K. Jain(Director)

Board seatAndrew ElBardissi· per SEC Form D · $6M raise · filed Nov 2022

Co-investorsTreo Ventures, LlcUS Venture Partners

HealthtechWoburn, US

Alan Abrams(Executive Officer, Director)Vince Cook(Executive Officer)Peter Dunphy(Executive Officer, Director)Douglas Thompson(Executive Officer, Director, Promoter)Craig Bass(Executive Officer)Jennifer Bryant(Executive Officer)

Board seatSteve AnastosJulian Harris· per SEC Form D · $45M raise · filed Sep 2020

Reprieve Cardiovascular develops a decongestion management system that uses real-time patient data to guide and personalize diuretic therapy for fluid removal in heart failure patients.

Digital HealthHealthtechMedical DevicesMilford, US

Tony Fields(Executive Officer)Adam Bartnik(Executive Officer)Mark Pacyna(Executive Officer, Director)inJim Dillon(Executive Officer, Director)Hanson S. Gifford III(Director)Gregory W Mann(Executive Officer)

Board seatAndrew ElBardissi· per SEC Form D

Co-investorsArboretum VenturesLightstone VenturesRex Health VenturesGenesis Venture CapitalSante Ventures

HealthtechTrumbull, US

Jia Jia Ye(Executive Officer, Director)Alexa Rachlin(Director)Missy Krasner(Director)

Board seatSteve AnastosJulian Harris· per SEC Form D · $18.1M raise · filed Nov 2020

Neomorph develops molecular glue degraders designed to target and degrade disease-causing proteins through engineered neomorphic protein surfaces.

BiotechDeep Tech

Co-investorsLongwood Fund

Cohere Health provides a platform aimed at aligning the interests of patients, physicians, and health plans to support care decisions and improve member outcomes.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechSaaSBoston, US

Siva Namasivayam(Executive Officer, Director)Robert Shepardson(Executive Officer)Kristen Carucci(Executive Officer)Duncan Reese(Executive Officer)

BoardDavid Barrett(Director)Amir Debourou(Director)

Co-investorsCota CapitalFlare Capital PartnersLongitude CapitalDefine VenturesFlare Capital StrategiesTemasek

Deerfield Catalyst is a medtech incubator that develops medical technology solutions aimed at improving patient outcomes and care delivery.

HealthtechMedical Devices

San Diego protein-sequencing company behind the ProteoCode platform; ceased operations in late 2025.

Co-investorsARCH Venture PartnersDecheng CapitalAlexandriaGV (Google Ventures)Nan Fung Life SciencesNorthpond Ventures

Frontier is a drug discovery company developing small-molecule covalent drugs aimed at previously undruggable protein targets across the proteome.

AI & Machine LearningBiotechSouth San Francisco, US

Chris Varma, Ph.D.(Executive Officer, Director)Chris Varma(Co-founder, Chairman and CEO)inJim Winkler(Executive Officer)Johannes Hermann, Ph.D.(Executive Officer)Kevin Webster(Executive Officer)Gregory Chow(Executive Officer)

Co-investorsBerkeley CatalystDCVC (Data Collective)Droia VenturesMPM BioImpactRA CapitalDCVC Bio

Clinical-stage genetic medicines company using human-derived AAV vectors and nuclease-free gene editing for rare diseases.

BiotechBedford, US

Siyamak Rasty(Executive Officer)Albert Seymour(Executive Officer)

BoardSteven Gillis(Director)Arthur Tzianabos(Executive Officer, Director)Kush Parmar(Director)inRichard Gregory(Director)

Co-investors5AM VenturesARCH Venture PartnersOUP (Osage University Partners)AlexandriaHBM Healthcare InvestmentsMaverick Ventures+4 more

Portland, US

Robert Gunn(Executive Officer, Director)Scott Fournier(Executive Officer)Mark Ronay(Executive Officer, Director)

BoardKaren Y. Spencer(Director)Jon C. Ohrn(Director)John Brewer, Jr.(Director)

Brooklyn, US

Marah Lidey(Executive Officer, Director)Naomi Hirabayashi(Executive Officer, Director)

BoardVictoria Song(Director)

Co-investorsComcast VenturesLaunchCapitalFidelity InvestmentsOaktreeSumitomo Corporation

HealthtechJanesville, US

Gregory Richard Piefer(Executive Officer, Director)Katrina Pitas(Executive Officer)Darin Janecek(Executive Officer)Anton Asmuth(Executive Officer, Director)James Costedio(Executive Officer)David A. Weissburg(Executive Officer, Director, Promoter)

Co-investorsVenture ManagementWisconsin Investment Partners

Somatus provides value-based, integrated kidney care and a congestive heart failure management solution for patients, providers, and health plan partners.

Digital HealthHealthtechMclean, US

Ikenna Okezie(Executive Officer, Director)Alexander Houlday(Executive Officer)Stacey Queen-Pyndell(Executive Officer)

BoardAnna Haghgooie(Director)Anthony Welters(Director)

Co-investorsFlare Capital PartnersOptum VenturesHealthQuest CapitalBlue Venture FundsDefy PartnersLongitude Capital+4 more

Soon is a portfolio management platform that automates buying and selling of assets across multiple exchanges using strategies like dollar-cost averaging and tax-loss harvesting.

Crypto & Web3FintechSalt Lake City, US

Michael Shattuck(Founder)in

Co-investorsY CombinatorFidelity InvestmentsOaktree

Strata Oncology develops precision oncology biomarkers and predictive diagnostic tools for cancer treatment, including treatment response scores for antibody-drug conjugates (ADCs) and an Immunotherapy Response Score for anti-PD-1/PD-L1 therapies.

AI & Machine LearningBiotechDigital HealthMedical DevicesAnn Arbor, US

Daniel Rhodes(Executive Officer, Director)Matthew Martin(Executive Officer)Jeffrey Williams(Executive Officer, Director)

BoardChristopher O'Donnell(Director)inDavid Rubin(Director)inJames Pavlik(Director)in

Co-investorsArboretum VenturesPfizer Venture InvestmentsMerck Global Health Innovation FundPfizer Ventures

Synthekine is a clinical-stage biotechnology company using protein engineering platforms to develop cytokine-based immunotherapies designed to preserve therapeutic efficacy while avoiding toxicities linked to cytokine pleiotropy.

BiotechHealthtech

K. Christopher Garcia(Founder)Susan Molineaux(CEO)Martin Oft(Chief Scientific Officer)Naiyer Rizvi(Chief Medical Officer)Gregory(Chief Technical Officer)Geoff(Chief Business Officer)

Co-investorsSamsara BioCapitalThe Column GroupBain Capital Life SciencesCanaan PartnersRA CapitalTCG Crossover+2 more

Endologix develops endovascular medical devices for treating vascular conditions such as abdominal aortic aneurysms and peripheral arterial disease in the femoropopliteal arteries.

HardwareHealthtechMedical Devices

John Liddicoat(President and Chief Executive Officer)Graham Phillips(Chief Operating Officer)Cindy Pinto(Chief Financial Officer)Jorge O'Hara(Chief Commercial Officer)

Co-investors415 CapitalNew Enterprise Associates (NEA)

Biotech applying AI and quantum simulation to nanomaterials and innovative drug delivery (SEHK: 07666).

Co-investorsHongShan Capital Group