Houston Angel Network

15Five provides a strategic performance management platform that helps businesses track employee engagement, performance, and retention through tools like performance reviews, goal tracking, and AI-powered manager coaching.

AI & Machine LearningHR TechSaaSSan Francisco, US

David Hassell(Executive Officer, Director)Shane Metcalf(Director)

BoardBrent Hill(Director)Matthew Cowan(Director)

23andMe operates a research platform that collects genetic data from millions of users to advance genomic research and health discovery.

BiotechDigital HealthDirect to ConsumerHealthtechLongevityMountain View, US

Anne Wojcicki(Co-founder & CEO)Linda Avey(Co-founder)Paul Cheung(Co-founder)Andrew Page(Executive Officer, Director)Kathy Hibbs(Executive Officer)

BoardEsther Dyson(Director)

BiotechPearland, US

Michael Hogan(Director)Mitchell Eggers(Executive Officer, Director)

BoardRobert Tucci(Director)

AgileDD offers a human-guided AI platform that ingests unstructured technical documents (PDFs, images, MS Office files, including handwriting via OCR) and extracts, indexes, and searches them using generative AI, machine learning, and RAG.

AI & Machine LearningEnterprise SoftwareSaaS

AI Driller provides a cloud-based operations platform for drilling and completions teams to plan, engineer, monitor, and execute wells in a single interface.

EnergyEnterprise SoftwareSaaS

BiotechWest Lafayette, US

Vincent Jo Davisson(Executive Officer, Director)Diana Caldwell(Executive Officer, Director)Andrew D Cothrel(Director)

BoardAndrew Cothrel(Director)Wade Lange(Director)Robert Saunders(Director)

AnaOno designs and sells bras and breast forms for people recovering from breast surgery and for everyday wear.

ConsumerFemTechHealthtechPhiladelphia, US

Dana DonofreeHarvey Hoffman(Director)W. Morgan Churchman(Director)

BoardSusan Nethero(Director)

Arovia manufactures Splay, a portable display device that combines a collapsible screen with ultra-short-throw projection technology for productivity, presentations, and entertainment.

ConsumerDeep TechHardwareNew MaterialsHouston, US

Alex(Co-founder, Optical Engineer)George(Co-founder, Mechanical Engineer)Alexander David Wesley(Executive Officer, Director)Taylor Yoke(Executive Officer, Director)Rahul Chandra(Executive Officer)Wesley D Alexander(Executive Officer, Director)

BiologicsMD develops recombinant fusion proteins targeting parathyroid hormone receptors for hair loss, bone disorders, and oncology treatments.

BiotechDeep TechMedical DevicesFayetteville, US

Robyn Goforth(Executive Officer)Rob Gensure(Executive Officer)J. David Owens(Executive Officer, Director)

BoardRamsay Ball(Director)Calvin Goforth(Director, Promoter)Lynn Kirkpatrick(Director)

Bodhi is a design-focused software company that provides customer experience software for the residential solar industry, using data automation and behavioral science to engage homeowners.

AI & Machine LearningCleantechEnergySaaS

Scott Nguyen(CEO)Kay Paulus(Head of Engineering)Jana LG(Head of Design)Stefanie Naden(Head of Customer Success)Jeff Bennett(Head of Product)

Medical device company developing cardiovascular diagnostic solutions.

Osteoboost is an FDA-cleared, drug-free prescription device that delivers precision vibration therapy to slow bone loss in postmenopausal women with osteopenia.

FemTechHealthtechMedical Devices

Endomedix is developing PLEXimine, a technology platform based on polysaccharide chemistry that lets surgeons form structured medical devices in situ during procedures.

BiotechMedical DevicesNew Materials

HeatGenie develops HeatGen, a patented self-heating packaging technology that uses a solid-state thermal reaction to heat ready-to-drink beverages inside the package in under two minutes.

FoodTechHardwareNew Materials

Boomerang's makes Australian-inspired frozen handheld foods, including meat pies, sandwiches, and rolls, made with flaky puff pastry and designed to be prepared in a microwave or air fryer.

ConsumerFoodTech

MMT develops nondestructive material testing and toughness verification technologies, including HSD (hardness, strength, ductility) and BTM (blade toughness meter) testers, to measure the durability of pipelines and other infrastructure without service interruption.

Deep TechEnergyHardware

CaseCtrl develops iQueue for Surgical Clinics, a digital surgical case management and scheduling platform for hospitals, ambulatory surgery centers, and private surgical practices.

Enterprise SoftwareHealthtechSaaSSugar Land, US

CellChorus develops a visual AI platform called TIMING that performs high-throughput dynamic analysis of single cells, measuring cell activation, killing, and movement over time for biopharmaceutical research.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesHouston, US

Dan Meyer(Founder)inNavin Varadarajan(Founder)inLaurence Cooper(Co-founder & Board Chair)Rebecca Berdeaux(Chief Scientific Officer)

ChowCall is a veteran-owned food ordering and delivery app that provides doorstep delivery from local restaurants to military bases and surrounding communities.

FoodTechLogistics & Supply ChainMarketplaces

Douglas G Richardson developed a patented animation technology for visual content creation, used by smartphone manufacturers and content platforms globally.

HardwareMedia & Entertainment

Douglas G Richardson

Medical DevicesAustin, US

John Uecker, M.D.(Executive Officer, Director)Douglas Stoakley(Executive Officer, Director)Frank Barbella(Director)John Uecker(Executive Officer, Director)

BoardBill Hale(Director)David Laverty(Director)

Corveus Medical develops a minimally-invasive catheter-based treatment that deactivates a sympathetic nerve branch to address heart failure progression.

HealthtechMedical DevicesHouston, US

Tyler Melton(Founder)inIshan Kamat(Chief Medical Officer)Byron Smith(VP of Engineering)

Davidson Instruments develops fiber optic pressure measurement systems for harsh industrial applications, including sensing technology used with advanced combustion control systems for jet engines and other industrial combustion turbine engines.

Deep TechEnergyHardware

Direct Kinetics (DKS) develops radioisotopic batteries based on beta-emitting isotope power sources, designed to provide continuous power for decades in an ultra-light form factor.

Deep TechHardwareSpace Tech

DrillDocs offers CleanSight, a non-invasive system that measures wellbore health and cuttings transport in real time by integrating with existing rig equipment and data systems.

Deep TechEnergyIoT

Edge Energy builds power infrastructure technology that generates reliable three-phase power from single-phase supply, avoiding costly grid upgrades.

CleantechEnergyHardware

Everix manufactures ultra-thin plastic optical filters designed to match the performance of traditional glass filters in systems with compact geometries, SWaP-C requirements, and non-flat or free-form optical surfaces.

Deep TechHardwareNew Materials

Exum develops the Massbox, a laser ablation laser ionization (LALI) analytical instrument for scientific labs that improves ionization efficiency and ease of use.

Deep TechHardwareNew MaterialsDenver, US

Jeffrey Williams(Executive Officer, Director, Promoter)Michael A Minyard(Executive Officer)James Thorson(Executive Officer, Director)Stephen Strickland(Director)

BoardPaul Giovacchini(Director)Doug Campbell(Director)

Eyetronic develops a non-invasive electrical stimulation therapy and system for patients with progressive visual field loss caused by glaucoma or other optic nerve diseases.

Digital HealthMedical Devices

Feel Therapeutics develops digital biomarkers and digital health solutions for mental health treatment, designed to function as standalone programs or alongside medications.

BiotechDigital HealthHealthtechMental HealthSan Francisco, US

Georgios Eleftheriou(Executive Officer, Director, Promoter)Charalampos Tsirmpas(Executive Officer, Director, Promoter)Irini Fragkiskou(Executive Officer)

BoardVica Manos(Director)Michel Vounatsos(Chairman of the advisory board, former CEO of Biogen)in

FluxWorks develops magnetic gearing technology for motion systems, replacing traditional mechanical gears with contactless magnetic solutions.

Advanced ManufacturingDeep TechHardwareRoboticsTexas, US

Bryton Praslicka(Chief Executive Officer)

BoardBradley Harrison(Director)

Houston, US

Abbasi N. Dhilawala(Executive Officer, Director)Christopher G. DuPont(Executive Officer, Director)Alexander L. Condon(Executive Officer)

Gecko Robotics builds robots equipped with sensors and cameras to inspect industrial structures like boilers for structural defects, replacing dangerous manual inspections at height.

Advanced ManufacturingAI & Machine LearningDeep TechRoboticsPittsburgh, US

Jake Loosararian(Founder/CEO)Troy Demmer(Founder/COO)

BoardGaetano Crupi(Director)Andrew Davis(Director)Trae Stephens(Director)

Cognota is a LearnOps platform for corporate learning and development (L&D) teams that unifies work orchestration, workflow tools, and AI agents into a single system.

AI & Machine LearningHR TechSaaSToronto

Laura Lenz(Director)Ryan Austin(Executive Officer, Director)David Sikora(Director)

Cognition Therapeutics is a clinical-stage biotechnology company developing zervimesine (CT1812), an investigational once-daily oral small-molecule therapy designed to protect brain synapses by blocking toxic protein oligomers.

BiotechHealthtech

Greasebook is mobile production software for independent oil and gas operators, letting field pumpers submit gauge data, run tickets, and tank readings from any phone so production numbers reach the office in real time.

Merge EDU is a web-based 3D learning platform for K-12 classrooms, offering a library of interactive 3D objects, science simulations, and real Earth data along with AI-assisted tools for students to create, scan, and generate 3D models.

AI & Machine LearningEdTechSaaS

Alameda, US

MetOx develops Xeus, a proprietary high-temperature superconductor (HTS) wire that carries high electrical current with near-zero energy loss.

Deep TechEnergyNew Materials

Hoth develops augmented reality software for healthcare providers to assist with surgical and procedural visualization.

AI & Machine LearningHealthtechMedical Devices

HugeDomains is a domain name marketplace that sells premium domain names to individuals and businesses, offering financing options and a buying guide.

E-commerceMarketplaces

Interobio Systems develops stem-cell-derived human intestinal organoids that include functioning neurons, blood vessels, muscle, and intestinal lining for use in preclinical drug testing.

BiotechDeep TechHealthtech

Charlie Childs(CEO)Madeline Eiken(CTO/COO)Jason Spence(CSO)

Joylux develops intimate and pelvic health products for women navigating menopause and midlife, including the FDA-cleared vFit red-light vaginal hydration device, hormone-free vaginal gels, moisturizers, and cleansers.

Direct to ConsumerFemTechWellness & FitnessSeattle, US

Colette Courtion(Founder)Robert Cross(Director)Richard Boxer(Director)Peter Weiss(Executive Officer)

KEY.co is a curated vacation rental platform offering a vetted selection of premium homes alongside add-on luxury services such as pre-arrival groceries, private chefs, and in-home massages.

ConsumerMarketplacesTravel & Hospitality

Knightscope develops autonomous security robots and related technology for physical security and public safety applications.

AI & Machine LearningDefense TechHardwareRoboticsMountain View, US

Stacy Dean Stephens(Executive Officer)William Santana Li(Chairman & Chief Executive Officer)

A consulting company that provides digital transformation services to enterprise businesses using Microsoft technologies and AI solutions.

AI & Machine LearningEnterprise SoftwareSaaS

Lazarus 3D produces patient-specific, 3D-printed anatomical models made from soft synthetic polymers that mimic human tissue, under its FDA-cleared Pre-Sure platform, so surgeons can rehearse incisions, sutures, and complex procedures before operating.

HardwareHealthtechMedical Devices

Jacques Zaneveld(Founder & CEO)Cheri Waddell(VP of Pre-Sure Products)

LegWorks develops prosthetic devices, including its All-Terrain Knee, designed to be lower-cost while maintaining high performance for amputees.

HardwareHealthtechMedical Devices

BiotechCrestwood, US

Angus McLachlan(Executive Officer, Director)

BoardAndrew Offer(Director)Cedric Francois(Director)John Landry(Director)John Moore(Director)Rod Wolford(Director)

Light Line Medical develops the PhotoDisinfection System, a light-based (photonics) technology that disinfects the inside and outside of translucent catheters, endotracheal tubes, and other medical devices to prevent and treat catheter-related infections.

Deep TechHealthtechMedical Devices

Waku makes canned tea beverages that are fruity and contain prebiotic fiber, positioned as an energetic alternative to traditional tea.

ConsumerDirect to ConsumerFoodTech