Early Stage Partners, LP
Venture capitalCleveland · Seed–Series A · 3 people tracked
Find your way into Early Stage Partners, LP
101 people in our graph share verified history with the Early Stage Partners, LP team — schools, employers, funds. One of them is your warm intro.
Investment thesis
Early Stage Partners focuses on backing promising early stage technology companies in the Midwest, based on the conviction that the region can produce a substantial number of attractive technology businesses. The firm provides much-needed capital along with advice and connections, aiming to generate success for entrepreneurs, investors, and the wider region. It has managed ESP Fund I (2002) and ESP Fund II (2008), both expected to reach top-quartile returns for their size and vintage. Notable exits include TOA Technologies (sold to Oracle), Simbionix, and Reverse Medical.
Source: firm website, verified Aug 3, 2026.
What founders say
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Team · 3 people
from the firm's website & public directoriesWhat they invest in
from 9 of 14 portfolio companiesHealthtech ×5Medical Devices ×4Biotech ×3Advanced Manufacturing ×2Digital Health ×2New Materials ×2SaaS ×2AdTech ×1
HQs:United States×10United Kingdom×1
Investments · 14 tracked
founders shown can be your intro pathBy year:2023 · 12020 · 12017 · 12015 · 12012 · 15 dated
SeaStar Medical develops the Selective Cytopheretic Device (SCD), a therapy that targets highly activated neutrophils and monocytes to neutralize the hyperinflammatory immune response in critically ill ICU patients facing conditions such as infection, trauma, or surgery.
BiotechHealthtechMedical DevicesDenver, US
H David Humes(Director)Eric Schlorff(Executive Officer, Director)inPeter DeComo(Director)Mark Morsfield(Executive Officer)inR James Danehy(Executive Officer, Director)Jen Baird, NACD.DCin
Co-investorsAphelion CapitalCapital Midwest FundWMU Biosciences Research & Commercialization Center
ICN provides cloud-based, real-time promotion and coupon management technology for retailers, handling trade, digital, paper, mobile, and direct-to-card coupons and points at the point of sale.
AdTechRetail TechSaaSNew Canaan, US
Richard Thibedeau(Co-Founder & Chief Operating Officer)Jon Robertson(Co-Founder & EVP Marketing)inBrian Schulte(Co-Founder & VP of IT)inGary Oakley(Executive Officer, Director)
BoardJames Petras(Director)Jonathan Murray(Director)
Co-investorsConnecticut InnovationsLaunchCapital
Ann Arbor, US
Eric Jacobson(Executive Officer)in
BoardPaul Vlasic(Director)Ellen Carnahan(Director)Richard Beedon(Director)Raymond Spencer(Director)Jay Katarincic(Director)in
Co-investorsDraper Triangle
Arisdyne provides process technologies for industrial applications, working with process engineers and plant managers to improve outcomes in areas such as biodiesel production, wastewater and biogas treatment, and graphene manufacturing.
Advanced ManufacturingCleantechDeep TechNew MaterialsCleveland, US
Frederick W. Clarke(Executive Officer, Promoter)Oleg Kozyuk(Executive Officer, Promoter)Peter Reimers(Executive Officer, Director)inDavid Coleman(Executive Officer)
BoardPaul DiBella(Director)Jim Mazzella(Director)
Blue Spark Technologies manufactures wearable medical devices for continuous patient monitoring in healthcare settings.
Digital HealthHealthtechIoTMedical DevicesWestlake, US
ROBERT THOMPSON(Executive Officer)John Gannon(President & CEO)inMatt Ream(Executive Vice President, Marketing and Innovation)inGARY TUCHOLSKI(Executive Officer)
BoardJAMES PETRAS(Director)inCECELIA CRUICKSHANK(Director)
Co-investorsSunbridge Partners
HistoSonics develops histotripsy technology, a non-invasive method that uses focused sound energy to destroy targeted tissue, offered as a medical device for physicians and their patients.
BiotechHardwareHealthtechMedical DevicesAnn Arbor, GB
Thomas Davison(Executive Officer, Director)inM. Christine Gibbons(Executive Officer, Director)inWen Chen(Director)Tom Tefft(Director)Michael Blue(Executive Officer, Director)Fred Lee(Director)
Co-investorsAlpha Wave GlobalAmzak HealthArboretum VenturesHealthQuest CapitalK5 GlobalLumira Ventures+5 more
Ischemia Care operates a CLIA-certified laboratory that develops blood tests for stroke patients using RNA expression analysis to determine stroke cause and improve clinical outcomes.
AI & Machine LearningDigital HealthHealthtechMedical DevicesOxford, US
Jeffrey June(Executive Officer, Director)Teresa June(Executive Officer)in
Co-investorsBroadview VenturesSolas BioVentures
OnShift provides workforce management and employee engagement software for long-term care, senior living, behavioral health, EMS, and home health providers.
Enterprise SoftwareHealthtechHR TechSaaSCleveland, US
Mark Woodka(Executive Officer, Director)in
BoardMichael Stubler(Director)Claiborne Rankin(Director)Jonathan Murray(Director)David Inglis(Director)
Co-investorsDraper TriangleHealth Velocity CapitalHLM Venture PartnersJumpstart Ventures
Ovation Polymers is a specialty engineered plastic compounder that produces custom and standardized performance polymers through processes including dispersion, reactive extrusion, grafting, and nano-material processing.
Advanced ManufacturingNew MaterialsMedina, US
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Linestream TechnologiesJuventas TherapeuticsReverse MedicalSimbionixTOA Technologies
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 1
1 IPOsSeaStar MedicalNASDAQ: ICU
Frequently asked questions
- How many investments has Early Stage Partners, LP made?
- Early Stage Partners, LP has 14 tracked investments, 1 of which have exited.
- What stage does Early Stage Partners, LP invest at?
- Early Stage Partners, LP invests at the Seed, Series A stages.
- What sectors does Early Stage Partners, LP focus on?
- Early Stage Partners, LP focuses on Biotech, Deep Tech, Energy, Enterprise Software, Hardware, Healthtech, Medical Devices, New Materials, SaaS.
- Where is Early Stage Partners, LP located?
- Early Stage Partners, LP is headquartered in Cleveland, US.
- Who does Early Stage Partners, LP co-invest with?
- Early Stage Partners, LP most often shares deals with Draper Triangle, Arboretum Ventures, Connecticut Innovations, among 16 tracked co-investors.
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