Chain Reaction
Angel networkBoston Β· Pre-SeedβSeed Β· 2 people tracked
Find your way into Chain Reaction
477 people in our graph share verified history with the Chain Reaction team β schools, employers, funds. One of them is your warm intro.
Investment thesis
Chain Reaction provides early-stage investors with curated access to blockchain startups through monthly meetings featuring vetted pitches, collaborative due diligence conducted with investors from varied industries, and a nationwide network of accredited investors and blockchain leaders. The platform emphasizes fast decision cycles and peer-driven evaluation to enable individual investors to build differentiated early-stage blockchain portfolios.
Source: firm website, verified Aug 6, 2026.
Team Β· 2 people
from curated
Founder mafia
2 people who came through Chain Reaction went on to found or lead other companies.
What they invest in
from 14 of 19 portfolio companiesCrypto & Web3 Γ9Fintech Γ8SaaS Γ6Enterprise Software Γ4AI & Machine Learning Γ2B2B Marketplaces Γ2Cloud Computing Γ2Gaming Γ2
HQs:United StatesΓ12
Who they back
founder profiles across 9 portfolio companiesFounding team size:solo founderΓ52 foundersΓ4
Accelerator rootsportfolio companies that came through a program
Investments Β· 19 tracked
founders shown can be your intro pathBeamable is an open, extensible game server platform that enables game developers to rapidly build and operate online games and virtual worlds.
Cloud ComputingDeveloper ToolsGamingSaaSBoston, US
Ali El Rhermoul(Founder)in
Co-investorsCompanyon VenturesGrandBanks CapitalAdvancit CapitalJoint EffectsREMUS CapitalBITKRAFT Ventures+1 more
Skybox AI is an AI tool that generates skybox environments and HDRI assets for game studios and creative professionals.
AI & Machine LearningCrypto & Web3GamingIndianapolis, US
Marguerite deCourcelle(Executive Officer, Director)in
Co-investorsNarcissus VenturesRed Beard VenturesTechstars6th Man VenturesAnimoca Brands
Corechain provides a B2B payments platform that enables paperless transactions and supply chain financing to unlock working capital for suppliers with approved but unpaid invoices.
B2B MarketplacesEnterprise SoftwareFintechSaaS
DigiBuild is a construction procurement platform that helps general contractors, subcontractors, and property owners source materials, reduce costs, and maintain project timelines.
AI & Machine LearningB2B MarketplacesConstruction TechEnterprise SoftwarePropTechSaaSMiami, US
Robert Salvador(Founder)inApril Moss(Co-Founder & former COO / Chief Customer Officer)inIvan Franco(Founder)in
Co-investorsPICUS CAPITALDraper AssociatesCathexis VenturesHelium-3 VenturesNeer Venture PartnersY Combinator+3 more
EirSystems builds medication management infrastructure for healthcare providers and EHR platforms, focusing on electronic medication administration records and opioid prescription monitoring across long-term care, behavioral health, and post-acute settings.
Digital HealthEnterprise SoftwareHealthtechMedical DevicesSaaSChattanooga, US
Robert Newman(Executive Officer, Director, Promoter)inRyan Seaberg(Co-Founder)Tyler Seaberg(Executive Officer, Director, Promoter)
Co-investorsAtlanta Technology AngelsSolas BioVentures
Gilded is a crypto payments and invoicing platform that helps finance teams manage accounts payable and receivable workflows using blockchain-based transactions.
Crypto & Web3FintechNew Orleans, US
Co-investorsNew Orleans Startup FundRed Beard VenturesTechstars
Co-investorsEntrepreneurs Roundtable Accelerator (ERA)Gossamer CapitalNew Layer CapitalSprint Vc
New Silver is a tech-enabled real estate lending platform offering fix-and-flip, ground-up construction, and 30-year rental loans to U.S. real estate investors, with online loan approval in under five minutes.
FintechPropTechSaaSWest Hartford, US
Kirill Bensonoff(Co-founder and CEO)inAlex Shvayetsky(Co-Founder and Head of Risk)in
NODE40 provides digital asset reporting infrastructure that reconstructs transaction-level history to support cost basis, lot identity, and reconciliation, producing outputs that can be traced and defended under audit or tax review.
Crypto & Web3FintechSaaSAlbany, US
Perry Phillip Woodin(Executive Officer)Sean David Ryan(Executive Officer)
Co-investorsWalnut Venture Associates
Crypto & Web3FintechStaten Island, US
Co-investorsChaos VenturesTechstars
RoundlyX offered a service that rounded up spare change to invest into cryptocurrency holdings held on users' chosen exchanges.
Crypto & Web3FintechRichmond, US
Alex Euler(Director)William Trible, III(Director)Andrew Elliott(Executive Officer, Director)
Co-investorsSound Media VenturesBlockchain Founders Fund
Play-to-earn game where users earn cryptocurrency using chicken NFTs to battle.
Co-investorsAlpha Moon CapitalGraviton FundSWGI Ventures (SWISS GEM INVESTMENTS)
Trustware provides programmable routing infrastructure that enables decentralized applications, institutions, and users to accept deposits from any blockchain by automatically routing and settling assets across chains with minimal integration effort.
Cloud ComputingCrypto & Web3Boston, US
Garett Curran(Founder)in
Co-investorsTechstars
Web3 Enabler builds Salesforce-native blockchain applications, distributed on the Salesforce AppExchange, that let businesses accept stablecoin payments, send global payments, and track client crypto holdings.
Crypto & Web3Enterprise SoftwareFintechHollywood, US
Alexander Michael Hochberger(Executive Officer, Director)Peter Hubshman(Executive Officer, Director)
BoardAlexander Smart(Director)
Exits Β· 1
IPOs and acquisitions across the tracked portfolioGildedacq. by Bitwave
Portfolio news
latest coverage across their companies
Gilded Β· theglobeandmail.com Β· Jul 13, 2026
DigiBuild Β· startupintros.com Β· Apr 15, 2026
TrustWare Β· trysignalbase.com Β· Oct 21, 2025
Frequently asked questions
- How many investments has Chain Reaction made?
- Chain Reaction has 19 tracked investments, 1 of which have exited via acquisition or IPO.
- What stage does Chain Reaction invest at?
- Chain Reaction invests at the Pre-Seed, Seed stages.
- What sectors does Chain Reaction focus on?
- Chain Reaction focuses on Crypto & Web3.
- Where is Chain Reaction located?
- Chain Reaction is headquartered in Boston, US.
- Does Chain Reaction lead rounds?
- Chain Reaction typically participates in rounds rather than leading them.
- Who does Chain Reaction co-invest with?
- Chain Reaction most often shares deals with Techstars, Red Beard Ventures, PICUS CAPITAL, among 29 tracked co-investors.
Similar investors
AirTree Ventures runs Pathfinders, a free four-week in-person program in Sydney for young builders (high-school graduates up to age 23) to work on a real product, access the AirTree team and founders, and build a peer network.
August Capital is a venture capital firm that invests in a small number of companies, providing hands-on support to entrepreneurs building their businesses.
.jpeg){kind=logo}
B Capital is a global investment firm backing early to late-stage technology innovators across technology, healthcare, and energy & resilience sectors.
Blueyard is a small equal partnership with offices in the US and Europe, investing in early-stage companies.
Breyer Capital is a venture capital firm that backs high-impact entrepreneurs, making strategic investments guided by founder passion and its network of experienced investors.