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Thetis Pharmaceuticals LLC

Southport, US · Founded 2011 · Connecticut LLC · 3 known investors

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Thetis is a clinical-stage pharmaceutical company developing TP-317, an oral Resolvin E1 drug that activates the BLT1 receptor to restore tissue and immune balance. It is being developed for inflammatory bowel disease, including ulcerative colitis, and solid tumors.

Founders & leadership

Thetis Pharmaceuticals LLC was founded in 2011 by Frank C Sciavolino and Gary Mathias.

FCFrank C Sciavolino
Frank C SciavolinoCo-Founder, President & Chief Scientific OfficerDr. Sciavolino spent 35 years at Pfizer Global R&D in various management and scientific roles across drug discovery, development, and registration, including work on antibiotic and COX-2 inhibitor programs, and served as Vice President overseeing R&D operations across multiple sites. He holds a Ph.D. in organic chemistry from the University of Michigan and a B.S. in pharmacy from St. John's University.
GMGary Mathias
Gary MathiasCo-Founder & CEO
JPJohn Parkinson
John ParkinsonChief Science Officer
JSJoyce Steinberg
Joyce SteinbergChief Medical Officer

Board

DM
David M WurzerManager
AM
Alan MendelsonManager
DW
Dennis WillsonManager

Investors · 3

Also in the syndicate · 1

Helmsley Charitable Trust

Reported raises · per SEC filings

Form D private placements

$7.4M disclosed across 4 of 5 rounds · 2016–2025

▶$1.1MraisedJul 2022 · 9 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • Gary MathiasExecutive Officer, Director
  • Frank C. SciavolinoDirector
  • Walter OgierDirector
  • Cynthia GreenDirector
  • Dennis F. WillsonDirector
Offering amount
$2M
Amount sold
$1.1M
Minimum investment
$10K
First sale
Jun 2022
Incorporated
Limited Liability Company, Connecticut
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$795.8KraisedAug 2018 · 8 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • David M WurzerDirector
  • Frank C SciavolinoExecutive Officer, Director
  • Dennis F WillsonDirector
  • Gary MathiasExecutive Officer, Director
  • Walter OgierDirector
Offering amount
$2.1M
Amount sold
$795.8K
First sale
Aug 2018
Incorporated
Limited Liability Company, Connecticut
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$4.1MraisedJan 2017 · 52 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • Dennis F WillsonDirector
  • David M WurzerDirector
  • Gary F MathiasExecutive Officer, Director
  • Frank C SciavolinoExecutive Officer, Director
  • Walter OgierDirector
Offering amount
$8M
Amount sold
$4.1M
Sales commissions
$200K
Placement agents
Fairport Capital, Inc.
First sale
Jun 2016
Incorporated
Limited Liability Company, Connecticut
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$1.4MraisedFeb 2016 · 16 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • Gary F MathiasExecutive Officer, Director
  • Dennis WillsonDirector
  • David M WurzerDirector
  • Frank C SciavolinoDirector
  • Alan MendelsonDirector
Offering amount
$4M
Amount sold
$1.4M
First sale
Jan 2016
Incorporated
Limited Liability Company, Connecticut, 2011
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Related companies · 3

Companies working in the same space as Thetis Pharmaceuticals LLC.

Non-dilutive funding · 10 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
National Institutes of Health (NIH)National Institutes of HealthPhase II2023$997.6K
National Institutes of Health (NIH)National Institutes of HealthPhase I2023$398.4K
National Institutes of Health (NIH)National Institutes of HealthPhase I2021$299.6K
National Institutes of Health (NIH)National Institutes of HealthPhase II2020$2M
National Institutes of Health (NIH)National Institutes of HealthPhase II2019$1.7M
National Institutes of Health (NIH)National Institutes of HealthPhase I2019$295.6K
National Institutes of Health (NIH)National Institutes of HealthPhase I2019$293.7K
National Institutes of Health (NIH)National Institutes of HealthPhase II2018$2M
National Institutes of Health (NIH)National Institutes of HealthPhase I2018$205.1K
National Institutes of Health (NIH)National Institutes of HealthPhase I2017$206K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

In the news

Frequently asked questions

What does Thetis Pharmaceuticals LLC do?
Thetis is a clinical-stage pharmaceutical company developing TP-317, an oral Resolvin E1 drug that activates the BLT1 receptor to restore tissue and immune balance. It is being developed for inflammatory bowel disease, including ulcerative colitis, and solid tumors.
Who founded Thetis Pharmaceuticals LLC?
Thetis Pharmaceuticals LLC was founded by Frank C Sciavolino, Gary Mathias in 2011.
Who are Thetis Pharmaceuticals LLC's investors?
Thetis Pharmaceuticals LLC's investors include Connecticut Innovations, Freemind Investments.
How much funding has Thetis Pharmaceuticals LLC raised?
Thetis Pharmaceuticals LLC has disclosed $7.4M raised across 4 of its 5 known rounds.
Where is Thetis Pharmaceuticals LLC headquartered?
Thetis Pharmaceuticals LLC is headquartered in Southport, US.