/Companies

IsoPlexis

New Haven, US · Founded 2014 · Delaware corporation · 5 known investors

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IsoPlexis offers the Cell Analysis Suite (CAS), software for its Beacon optofluidic platform that lets researchers design, automate, and analyze functional live single-cell workflows. It serves life-science researchers working in areas such as antibody discovery, cell line development, T cell profiling, and adoptive cell therapy.

Founders & leadership

IsoPlexis was founded in 2014 by Rong Fan, Sean McKay, and Sean Mackay.

RF
Rong FanCo-founder
SM
Sean McKayCo-founder
SM
Sean MackayCo-founder
RK
Raj Khakhar
JZ
Jing Zhou

Board

DW
Daniel WagnerBoard director
JCJohn Conley
John ConleyChair, Board Of Directors2014–2023Board Member at Launchpad Venture Group
GH
Gregory HoBoard director

Investors · 5

Funding

SEC filings, press & company announcements

$127M disclosed across 7 of 8 rounds · 2014–2021

▶$7.5MraisedJan 2021 · 1 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • John StrahleyExecutive Officer
  • Sean MackayExecutive Officer, Director
  • John ConleyDirector
  • GREGORY HODirector
  • DANIEL WAGNERDirector
  • JAMES HEATHDirector
  • MICHAEL EGHOLMDirector
  • SHARON KEDARDirector
Offering amount
$7.5M
Amount sold
$7.5M
First sale
Dec 2020
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$85MraisedJan 2021 · 10 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • DANIEL WAGNERDirector
  • GREGORY HODirector
  • John ConleyDirector
  • Sean MackayExecutive Officer, Director
  • MICHAEL EGHOLMDirector
  • SHARON KEDARDirector
  • John StrahleyExecutive Officer
  • JAMES HEATHDirector
Offering amount
$85M
Amount sold
$85M
First sale
Dec 2020
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$19.6MraisedNov 2018 · 6 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • Daniel WagnerDirector
  • Sean MackayExecutive Officer, Director
  • James HeathDirector
  • Gregory HoDirector
  • John ConleyDirector
Offering amount
$25M
Amount sold
$19.6M
First sale
Nov 2018
Incorporated
Corporation, Delaware, 2014
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$5.4MraisedAug 2017 · 4 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • James HeathDirector
  • John ConleyDirector
  • Sean MackayExecutive Officer, Director
  • Daniel WagnerDirector
  • Gregory HoDirector
Offering amount
$6.4M
Amount sold
$5.4M
First sale
Jul 2017
Incorporated
Corporation, Delaware, 2014
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$5.7MraisedJun 2016 · 5 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • Sean McKayExecutive Officer, Director
  • James HeathDirector
  • Rong FanDirector
  • Gregory HoDirector
  • Daniel WagnerDirector
Offering amount
$8M
Amount sold
$5.7M
First sale
Jun 2016
Incorporated
Corporation, Delaware, 2014
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$2.4MraisedMay 2015 · 4 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • Daniel WagnerDirector
  • John ConleyDirector
  • Gregory HoDirector
  • Rong FanDirector
  • Sean McKayExecutive Officer, Director
Offering amount
$3.8M
Amount sold
$2.4M
First sale
May 2015
Incorporated
Corporation, Delaware, 2014
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$1.3MraisedJul 2014 · 7 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Sean MackayExecutive Officer, Director
Offering amount
$1.7M
Amount sold
$1.3M
First sale
Jul 2014
Incorporated
Corporation, Delaware, 2013
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Non-dilutive funding · 17 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
National Institutes of Health (NIH)National Institutes of HealthPhase II2020$2M
National Institutes of Health (NIH)National Institutes of HealthPhase II2019$4M
National Institutes of Health (NIH)National Institutes of HealthPhase II2019$2M
National Institutes of Health (NIH)National Institutes of HealthPhase II2019$2M
National Institutes of Health (NIH)National Institutes of HealthPhase I2019$224.9K
National Institutes of Health (NIH)National Institutes of HealthPhase I2018$224.9K
National Institutes of Health (NIH)National Institutes of HealthPhase I2018$224.6K
National Institutes of Health (NIH)National Institutes of HealthPhase I2018$163.7K
National Institutes of Health (NIH)National Institutes of HealthPhase II2017$1.9M
National Institutes of Health (NIH)National Institutes of HealthPhase II2017$1.9M
National Institutes of Health (NIH)National Institutes of HealthPhase II2017$1.8M
National Institutes of Health (NIH)National Institutes of HealthPhase II2017$1.7M
National Institutes of Health (NIH)National Institutes of HealthPhase I2017$162.5K
National Institutes of Health (NIH)National Institutes of HealthPhase I2016$164K
National Institutes of Health (NIH)National Institutes of HealthPhase I2016$164K
National Institutes of Health (NIH)National Institutes of HealthPhase I2016$160.3K
National Institutes of Health (NIH)National Institutes of HealthPhase I2015$182K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

In the news

Frequently asked questions

What does IsoPlexis do?
IsoPlexis offers the Cell Analysis Suite (CAS), software for its Beacon optofluidic platform that lets researchers design, automate, and analyze functional live single-cell workflows. It serves life-science researchers working in areas such as antibody discovery, cell line development, T cell profiling, and adoptive cell therapy.
Who founded IsoPlexis?
IsoPlexis was founded by Rong Fan, Sean McKay, Sean Mackay in 2014.
Who are IsoPlexis's investors?
IsoPlexis's investors include Connecticut Innovations, Ally Bridge Group, Ironwood Capital, Northpond Ventures, Spring Mountain Capital.
How much funding has IsoPlexis raised?
IsoPlexis has disclosed $127M raised across 7 of its 8 known rounds.
Where is IsoPlexis headquartered?
IsoPlexis is headquartered in New Haven, US.