Thomas James
Angel networkPre-Seed–Series A · 2 people tracked
Find your way into Thomas James
Sign up to see every warm intro you have to Thomas James
- Paths you didn't know you had: your email and LinkedIn already hold routes to the Thomas James team. We find them
- 2nd- and 3rd-degree connections: the friend-of-a-friend routes you can't see from your own inbox or LinkedIn
- Answers now, not in days: momentum is everything in a raise. Skip asking around whether someone knows someone
Days of research, done the moment you sign in, with every route ranked by how warm it is.
Investment thesis
Purexs is Tom James's personal investment platform, focused primarily on supporting companies he has already backed while occasionally investing or advising where the fit is exceptional. Having built companies, taken two to IPO and backed roughly 300 startups, he looks for unusual, driven founders tackling hard problems with the potential to build something meaningful. His focus spans category-defining software, climate, health and deep technology. He operates with no investment committee, offering founders direct questions, candid feedback and quick answers, and is most useful at high-stakes moments such as finding product-market fit, shaping a round, making introductions or working through strategic decisions.
Source: firm website, verified Oct 3, 2026.
Team · 2 people
from the firm's website & public directoriesWhat they invest in
from 34 of 48 portfolio companiesAI & Machine Learning ×13Enterprise Software ×10Healthtech ×10Advanced Manufacturing ×7Cleantech ×7Medical Devices ×7SaaS ×7Biotech ×6
HQs:United States×14United Kingdom×5Singapore×3Canada×2Australia×1Belgium×1
Who they back
founder profiles across 14 portfolio companiesFounding team size:solo founder×32 founders×33 founders×24+ founders×6
Where their founders studiedfrom 35 founders with education data
Ghent University ×3Harvard University ×3Imperial College London ×3Massachusetts Institute of Technology ×3Stanford University ×2The London School of Economics and Political Science (LSE) ×2The University of Western Australia ×2University of Toronto ×2
What their founders studiedfrom 33 founders with field-of-study data
Engineering ×13Computer Science ×12Mathematics & Statistics ×4Physics ×4Business & Management ×3Finance & Accounting ×3Economics ×2Humanities ×2
Where their founders worked beforefrom 34 founders with career history
Google ×8OpenAI ×8Stanford University ×3Google Deepmind ×2Stripe ×2
Accelerator rootsportfolio companies that came through a program
13 founders hold a PhD · 1 hold an MBA (of 34 with degree data)
Investments · 48 tracked
founders shown can be your intro pathBy year:2021 · 12019 · 23 dated
Acadian Ventures is an early-stage venture capital firm focused on the Future of Work, investing in companies such as Nomi Health, Oyster, SmartRecruiters, Degreed, and Utmost.
Enterprise SoftwareFuture of WorkSaaS
Jason Corsello(Founder & General Partner)inThomas Otter(General Partner)in
Co-investorsConnecticut InnovationsPeakEmblemFELIX CAPITALNotion CapitalUgly Duckling Ventures
Anthropic is an AI safety research company that builds reliable, interpretable, and steerable AI systems.
AI & Machine LearningDeep TechDeveloper ToolsEnterprise SoftwareSan Francisco, US
Dario Amodei(Founder)inDaniela Amodei(Founder)inTom Brown(Founder)inJack Clark(Founder)inJared Kaplan(Founder)inChris Olah(Founder)in
Co-investors3Comma Capital7BC Venture Capital7GC & CoA.Capital VenturesAccelAkka+151 more
AppFactor offers an agentic platform that discovers where applications are running, analyzes application portfolios, dependencies, and infrastructure for vulnerabilities and misconfigurations, and generates containers and deployment artifacts for cloud-native, hybrid, and multi-cloud environments.
AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise Software
Co-investorsAdara VenturesBegin Capital
Astek Diagnostics develops a diagnostic platform for rapid and accurate detection of urinary tract infections and related conditions in clinical specimens.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesBaltimore, US
Mustafa Al-Adhami(Founder)inCourtney Cavin(Cofounder)in
Co-investorsMaryland TEDCOTEDCOY CombinatorAJGAYANA Capital LLCBuilder Capital+4 more
Atomic Alchemy developed technology and facilities for producing radioisotopes for medical, industrial, and research applications, planning dedicated isotope-production reactors in Idaho.
Advanced ManufacturingCleantechClimate TechDeep TechEnergyRoboticsIdaho Falls, US
Thomas Eiden(Founder)in
Co-investorsAsymmetry VenturesBreakwater VenturesDCVC (Data Collective)Divergent CapitalHemisphere Ventures LLCSeaChange+3 more
Design platform; Blackbird invested when it was just an idea and in every round since.
SocialSurry Hills, Nsw, AU
Melanie Perkins(Founder)inClifford Obrecht(Executive Officer, Director)Cliff Obrecht(Founder)inCameron Adams(Founder)inIan LeeJeffrey Story
Co-investors3Spoke Capital500 GlobalAirTree VenturesAlkeon InnovationAlpha Square GroupAltra Venture+58 more
Circuit Mind develops a platform that converts hardware architecture into verified schematics and bills of materials using algorithms and software for electronics engineers and design teams.
Advanced ManufacturingAI & Machine LearningDeveloper ToolsHardwareLondon, GB
EdTomide Adesanmi(CEO)inBasilio Gentile(CTO)in
Co-investors7percent VenturesBlackhorn VenturesCreative VenturesDifferential VenturesEntrepreneur FirstEpisode1+6 more
Credpal operates a financial platform that integrates payments, savings, credit, and investments for individuals in Africa.
FintechLagos, NG
Mofehintolu Olaogun(Founder)inFehintolu Olaogun(Founder)Olorunfemi Jegede(Founder)
Co-investorsAcasia VenturesCairo Angels Syndicate FundFirst CircleMAVA VenturesStacked CapitalY Combinator+5 more
CustomerOS is a B2B marketing platform powered by AI agents that identifies target prospects, analyzes pipeline data, and optimizes marketing spend to drive revenue.
AI & Machine LearningEnterprise SoftwareMarketing TechSaaSSales TechLondon, GB
Matt Brown(Founder)inVasi Coscotin(Founder)inJonty Knox(Founder)in
Co-investorsY CombinatorCocoaCrane Venture PartnersLatam Venture CapitalSequoia Capital
A plastic chemical recycling company specializing in advanced recycling technology and plant operations for the circular economy sector.
Circular EconomyCleantechDeep TechNew MaterialsSwindon, GB
Marvine Besong(CEO)in
BoardSimon Ashby-Rudd(Chair)
Co-investorsEMV Capital
Docbot developed AI-powered software for gastroenterology, using computer vision to detect polyps and assist diagnosis during endoscopy and colonoscopy procedures.
ConsumerGamingHealthtechLos Angeles, US
Tyler Dao(Founder)inWilliam Karnes(Founder)inAndrew Ninh(Founder)in
Co-investorsBold Capital PartnersBoutique Venture PartnersY CombinatorApplied AngelsBankia Fintech VentureCollaborative Fund+5 more
Drapr provides virtual try-on technology for clothing that enables shoppers to preview apparel online and helps brands increase their digital sales.
ConsumerE-commerceSaaSSan Francisco, US
David Pastewka(Founder)inRichard Berwick(Founder)inWill Drevno(Founder)in
Co-investorsCabra VCNeer Venture PartnersSmart Partnership CapitalY CombinatorBamboo Capital PartnersBoost VC+2 more
Flow is a hardware development platform that uses AI to help engineering teams keep requirements, architecture, and verification aligned across complex vehicle programs.
Advanced ManufacturingAI & Machine LearningDeveloper Tools
Pari Singh(Founder)in
Co-investorsAir Street CapitalBackedDeep Science VenturesSequoia CapitalAtreides ManagementEntrepreneur First+3 more
Greenpixie provides emissions measurement and cloud sustainability services to engineering teams, helping them reduce waste and improve efficiency in cloud operations.
AI & Machine LearningCleantechClimate TechCloud Computing
Co-investorsAscensionGreen Angel VenturesOctopus VenturesBeringea
homeDAO is a residential accelerator program in Oxford that provides free accommodation, workspace, and $350k SAFE funding to founders building early-stage companies.
EdTechFuture of WorkOxford, GB
Co-investorsPragma Ventures
Instapath develops rapid digital pathology microscopy platforms that enable cancer diagnosis from tissue samples in minutes rather than days.
BiotechDeep TechHealthtechMedical DevicesHouston, US
Mei Wang(Founder)inQuincy Brown(Founder)inDavid Tulman(Founder)in
Co-investorsDraper AssociatesY CombinatorVenture Investment Associates
Intelline develops CAVIE modular power systems for industrial applications, offering scalable distributed power generation with fuel-agnostic capability and up to 40% improved fuel efficiency.
Advanced ManufacturingCleantechClimate TechEnergyHardwareRoboticsWaterloo, CA
Kyle Faller(Founder)inChris Mathew(Founder)in
Co-investorsPioneerY CombinatorAgrolimen VenturesBamboo Capital PartnersLLLP
Isabl develops whole genome and transcriptome sequencing technology for cancer diagnosis, delivering comprehensive genomic profiling and treatment options to physicians and research teams.
BiotechDigital HealthHealthtechMedical DevicesNew York City, US
Juan Medina(CTO and Technical Co-founder)inAndrew Kung(MD PhD, Medical Co-Founder)inElli Papaemmanuil(PhD, CEO and Scientific Co-founder)in
Co-investorsY CombinatorBoxOne VenturesTwo Sigma VenturesEvolution VC PartnersSand Hill AngelsAmino Capital
Jenfi offers revenue-based financing to digital businesses across Asia, tying repayment obligations to customer revenue.
FintechSingapore, SG
Jeffrey Liu(Founder)inJustin Louie(Founder)inJeffrey Liu Justin Louie(Founder)
Co-investorsICU VenturesITERATIVEMonk's Hill VenturesTaurus VenturesVentureSouqY Combinator+9 more
Lamar Health provides workflow automation software for specialty pharmacies and infusion organizations, enabling teams to manage prior authorization processes and patient access workflows.
AI & Machine LearningHealthtechMedia & EntertainmentSaaSSan Francisco, US
Eesha Sharma(Founder)in
Co-investorsDniproHealthy VenturesPenny Jar Capital VentureY CombinatorFlex Capital PartnersFlexcap Ventures+5 more
Luminate develops medical device technology to address chemotherapy side effects, particularly hair loss and peripheral neuropathy, for oncology patients and healthcare providers.
BiotechDigital HealthHealthtechMedical DevicesGalway, US
Aaron Hannon(Founder)inBarbara Oliveira(Founder)inProf. Martin O'Halloran(Co-Founder)JAMES EVERINGHAM(Executive Officer, Director)Eldad Livni(Founder)Leonid Belkind(Founder)
Co-investorsSciFoundersY Combinator8VCArtis VenturesAtlantic Bridge VenturesFaber+13 more
Lunasonde develops aerial georadiotomography (aGRT) technology that uses low-frequency radar to create 3D compositional images of the subsurface from aircraft, helicopters, drones, and balloons.
AgTechCleantechClimate TechDeep TechEnergyCortaro, US
Jeremiah Pate(Executive Officer, Director, Promoter)inHILLARY PATE(Executive Officer)
Co-investorsActuate VenturesBantam GroupDrive CapitalKluz VenturesPure VenturesTechstars+2 more
OneLogin provides cloud-based identity and access management (CIAM) solutions that enable organizations to securely manage user authentication and application access across their enterprise infrastructure.
Cloud ComputingCybersecurityEnterprise Software
Christian Pedersen(Founder)Thomas Pedersen(Founder)
Co-investorsCRV (Charles River Ventures)Kleiner PerkinsScale Venture Partners
OpenAI is an AI research and deployment company focused on developing artificial general intelligence (AGI) with emphasis on safety and beneficial outcomes for humanity.
AI & Machine LearningCloud ComputingEnterprise SoftwareSan Francisco, US
Sam Altman(Founder)Elon Musk(Founder)inGreg Brockman(Founder)inIlya Sutskever(Founder)inWojciech Zaremba(Founder)inJohn Schulman(Founder)
Co-investors7BC Venture CapitalA-Rod CorpA.Capital VenturesA'Z AngelsAdvent InternationalAliya Capital Partners+98 more
Percept.AI builds AI systems that handle customer support interactions for businesses, using natural language processing to improve support team productivity and responsiveness.
AI & Machine LearningEnterprise SoftwareSaaSSan Francisco, US
Joe (Zhou) Sha(Founder)inDeyang (Derek) Zhao(Founder)inShuo Han(Founder)in
Co-investorsIncubate USY CombinatorAmino CapitalBuilders VCCherubic VenturesCyphr+5 more
Phoenix Tailings develops clean technology for rare earth element refining in the United States.
Advanced ManufacturingCleantechClimate TechEnergyFintechNew MaterialsBoston, US
Thomas Villalón(Chief Technology Officer & Co-Founder)Anthony Balladon(Founder)inMichelle Chao(Founder)inNick Myers(Chief Executive Officer & Co-Founder)inNicholas Myers(Founder)Tomas Villalon(Founder)
Co-investorsBantam GroupBMW i VenturesCoalitionGeodesic CapitalIn-Q-TelMPower+13 more
Seal provides a software platform that replaces paper and legacy systems for managing GxP (good manufacturing and laboratory practices) work, with built-in AI assistance for process improvement, validation tracking, and compliance records in pharmaceutical and life sciences manufacturing.
AI & Machine LearningBiotechEnterprise SoftwareHealthtechSaaSLondon, GB
Will Moss(Founder)inJonathan Dench(Founder)in
Co-investorsEntrepreneur FirstJude GomilaY CombinatorAllison Pickens VenturesAndreessen HorowitzASDF Ventures+6 more
SepPure Technologies develops nano-filtration membrane technology that replaces conventional energy-intensive chemical separation processes, reducing solvent use, energy consumption, and emissions.
Advanced ManufacturingCleantechClimate TechDeep TechNew MaterialsSingapore, SG
Mohammad Farahani(CEO)inAmir Hooshang Taheri(Founding CTO)in
Co-investors500 GlobalEntrepreneur FirstUntroD CapitalSEEDS CapitalSOSV
SpaceRyde develops reusable spacecraft that deploy via stratospheric balloon and establish an orbital network to perform cargo transport and on-demand in-space services such as refueling, deep-space missions, and debris removal.
Advanced ManufacturingHardwareSpace TechSan Francisco, US
Sohrab Haghighat(Founder)in
Co-investorsBackbone AngelsPi CampusY CombinatorAutomation VenturesChainFund CapitalLiquid Ventures+5 more
TechWolf builds AI-driven skills intelligence software that helps enterprises unlock and manage talent based on skills rather than job titles or credentials.
AI & Machine LearningEnterprise SoftwareHR TechSaaSGhent, BE
Mikael Wornoo(Founder)inAndreas De Neve(Founder)inJeroen Van Hautte(Founder)inYasamin Karimi(Chief Product Officer)in
Co-investors20VCAcadian Ventures Management, LlcFELIX CAPITALNotion CapitalPMVSemperVirens Venture Capital+4 more
Tessian provides AI-powered email security solutions that detect and prevent email-based cyberattacks and data loss for enterprises.
AI & Machine LearningCybersecurityEnterprise Software
Tim Sadler(Founder)inEdward Bishop(Founder)inEd Bishop(Founder)Thomas Adams(Founder)Tom Adams(Founder)
Co-investorsAccelBalderton CapitalCrane Venture PartnersForgePoint CapitalLocalGlobeMarch Capital Partners+9 more
Trexo develops a robotic device that enables children with cerebral palsy and other mobility disabilities to walk independently at home.
HealthtechMedical DevicesRoboticsToronto, CA
Manmeet Maggu(Founder)inRahul Udasi(Founder)in
Co-investorsFoundersFoundersX VenturesGeekdomJoyance Partnerskineo financeSocial Starts+9 more
Two Plus Fertility is a fertility and reproductive health service or platform.
Digital HealthDirect to ConsumerFemTechHealthtechMedical DevicesWellness & FitnessSingapore, SG
Prusothman Raja(Founder)inBenjamin Tee(Founder)in
Co-investorsAnthro VenturesGolden Gate VenturesKube VCY CombinatorBamboo Capital PartnersJosh Hannah+4 more
Unima makes portable diagnostic tests that deliver disease identification at the point of care within 15 minutes at low cost, enabling rapid detection and monitoring of infectious diseases.
BiotechHealthtechMedical DevicesZapopan, MX
Rodrigo Nuno(Founder)inMaria Laura Mendoza(Founder)inAlejandro Nuño Ayala(Founder)inLaura Mendoza(Founder)
Co-investorsY CombinatorAgrolimen VenturesAJGAvalancha VenturesIDrive VenturesInvesto Capital+2 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AegiqAIWorkifyBlinkBraveCognismGluwaIntec TelecomloveholidaysMessiumOkloOverwolfUmantisVSIMZendesk
Exits · 4
4 acquisitions · showing 2Atomic Alchemyacq. by OkloPercept.AIacq. by Atlassian
Portfolio news
latest coverage across their companies
Flow Engineering · techcrunch.com · Sep 30, 2026

Anthropic · Anthropic Newsroom · Aug 4, 2026
OpenAI · openai.com · Jul 21, 2026
Greenpixie · finsmes.com · May 18, 2026
Trexo Robotics · trexorobotics.com · Mar 30, 2026
Phoenix Tailings · finsmes.com · Feb 20, 2026
Luminate · finsmes.com · Jan 7, 2026
CustomerOS · ycombinator.com · Sep 24, 2025
Frequently asked questions
- How many investments has Thomas James made?
- Thomas James has 48 tracked investments, 4 of which have exited.
- What stage does Thomas James invest at?
- Thomas James invests at the Pre-Seed, Seed, Series A stages.
- What sectors does Thomas James focus on?
- Thomas James focuses on Advanced Manufacturing, AI & Machine Learning, Cleantech, Climate Tech, Consumer, Cybersecurity, Deep Tech, Enterprise Software, Fintech, Healthtech, New Materials, Quantum Computing, SaaS.
- Who does Thomas James co-invest with?
- Thomas James most often shares deals with Bantam Group, Entrepreneur First, In-Q-Tel, among 71 tracked co-investors.
Similar investors
Khosla Ventures is a venture capital firm that backs bold, early-stage, technology-driven companies across deep tech and other sectors, providing hands-on 'venture assistance' to help founders build category-defining businesses.
Everywhere Ventures is an early-stage venture firm that writes pre-seed checks and is backed by a community of founder and operator LPs.
Shastra VC is an early-stage venture firm backing founders in frontier tech, climate tech, and AI, investing at the pre-proof 'belief' stage.
Maverick Ventures Israel is an early-stage venture capital firm founded by entrepreneurs, backing Israeli technology startups across diverse industries with capital and operational support.
Alpha Edison is an early-stage venture firm that partners with entrepreneurs using technology to unlock latent demand in markets where consumer and business behaviors are shifting.






























































































-2.png)























































































