/Investor DB

Thomas James

Angel network

Pre-Seed–Series A · 2 people tracked

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Investment thesis

Purexs is Tom James's personal investment platform, focused primarily on supporting companies he has already backed while occasionally investing or advising where the fit is exceptional. Having built companies, taken two to IPO and backed roughly 300 startups, he looks for unusual, driven founders tackling hard problems with the potential to build something meaningful. His focus spans category-defining software, climate, health and deep technology. He operates with no investment committee, offering founders direct questions, candid feedback and quick answers, and is most useful at high-stakes moments such as finding product-market fit, shaping a round, making introductions or working through strategic decisions.

Source: firm website, verified Oct 3, 2026.

Stage
Pre-Seed–Series A
Instruments
Equity
Tracked investments
48
Unicorns
3
Acquisitions
4

Team · 2 people

from the firm's website & public directories

What they invest in

from 34 of 48 portfolio companies

AI & Machine Learning ×13Enterprise Software ×10Healthtech ×10Advanced Manufacturing ×7Cleantech ×7Medical Devices ×7SaaS ×7Biotech ×6

HQs:United States×14United Kingdom×5Singapore×3Canada×2Australia×1Belgium×1

Who they back

founder profiles across 14 portfolio companies
21%
solo founders
3 of 14 mapped founding teams
38%
repeat founders
of 34 founders with career history

Founding team size:solo founder×32 founders×33 founders×24+ founders×6

Where their founders studiedfrom 35 founders with education data

Ghent University ×3Harvard University ×3Imperial College London ×3Massachusetts Institute of Technology ×3Stanford University ×2The London School of Economics and Political Science (LSE) ×2The University of Western Australia ×2University of Toronto ×2

What their founders studiedfrom 33 founders with field-of-study data

Engineering ×13Computer Science ×12Mathematics & Statistics ×4Physics ×4Business & Management ×3Finance & Accounting ×3Economics ×2Humanities ×2

Where their founders worked beforefrom 34 founders with career history

Google ×8OpenAI ×8Stanford University ×3Google Deepmind ×2Stripe ×2

Accelerator rootsportfolio companies that came through a program

Entrepreneur First ×2Techstars ×2

13 founders hold a PhD · 1 hold an MBA (of 34 with degree data)

Investments · 48 tracked

founders shown can be your intro path

By year:2021 · 12019 · 23 dated

Acadian Venturesacadianventures.comin

Acadian Ventures is an early-stage venture capital firm focused on the Future of Work, investing in companies such as Nomi Health, Oyster, SmartRecruiters, Degreed, and Utmost.

Enterprise SoftwareFuture of WorkSaaS

Jason Corsello(Founder & General Partner)inThomas Otter(General Partner)in

Co-investorsConnecticut InnovationsPeakEmblemFELIX CAPITALNotion CapitalUgly Duckling Ventures

Anthropicanthropic.comin𝕏

Anthropic is an AI safety research company that builds reliable, interpretable, and steerable AI systems.

AI & Machine LearningDeep TechDeveloper ToolsEnterprise SoftwareSan Francisco, US

Dario Amodei(Founder)inDaniela Amodei(Founder)inTom Brown(Founder)inJack Clark(Founder)inJared Kaplan(Founder)inChris Olah(Founder)in

Co-investors3Comma Capital7BC Venture Capital7GC & CoA.Capital VenturesAccelAkka+151 more

AppFactorappfactor.ioin

AppFactor offers an agentic platform that discovers where applications are running, analyzes application portfolios, dependencies, and infrastructure for vulnerabilities and misconfigurations, and generates containers and deployment artifacts for cloud-native, hybrid, and multi-cloud environments.

AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise Software

Co-investorsAdara VenturesBegin Capital

Astek Diagnosticsastekdx.cominSeed

Astek Diagnostics develops a diagnostic platform for rapid and accurate detection of urinary tract infections and related conditions in clinical specimens.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesBaltimore, US

Mustafa Al-Adhami(Founder)inCourtney Cavin(Cofounder)in

Co-investorsMaryland TEDCOTEDCOY CombinatorAJGAYANA Capital LLCBuilder Capital+4 more

Atomic Alchemyatomicalchemy.usin𝕏Seedacquired by Oklo

Atomic Alchemy developed technology and facilities for producing radioisotopes for medical, industrial, and research applications, planning dedicated isotope-production reactors in Idaho.

Advanced ManufacturingCleantechClimate TechDeep TechEnergyRoboticsIdaho Falls, US

Thomas Eiden(Founder)in

Co-investorsAsymmetry VenturesBreakwater VenturesDCVC (Data Collective)Divergent CapitalHemisphere Ventures LLCSeaChange+3 more

Canvacanva.com

Design platform; Blackbird invested when it was just an idea and in every round since.

SocialSurry Hills, Nsw, AU

Melanie Perkins(Founder)inClifford Obrecht(Executive Officer, Director)Cliff Obrecht(Founder)inCameron Adams(Founder)inIan LeeJeffrey Story

Co-investors3Spoke Capital500 GlobalAirTree VenturesAlkeon InnovationAlpha Square GroupAltra Venture+58 more

CircuitMind Inc.circuitmind.ioin

Circuit Mind develops a platform that converts hardware architecture into verified schematics and bills of materials using algorithms and software for electronics engineers and design teams.

Advanced ManufacturingAI & Machine LearningDeveloper ToolsHardwareLondon, GB

EdTomide Adesanmi(CEO)inBasilio Gentile(CTO)in

Co-investors7percent VenturesBlackhorn VenturesCreative VenturesDifferential VenturesEntrepreneur FirstEpisode1+6 more

CredPalcredpal.comin𝕏Seed

Credpal operates a financial platform that integrates payments, savings, credit, and investments for individuals in Africa.

FintechLagos, NG

Mofehintolu Olaogun(Founder)inFehintolu Olaogun(Founder)Olorunfemi Jegede(Founder)

Co-investorsAcasia VenturesCairo Angels Syndicate FundFirst CircleMAVA VenturesStacked CapitalY Combinator+5 more

CustomerOScustomeros.aiin𝕏SeedDefunct

CustomerOS is a B2B marketing platform powered by AI agents that identifies target prospects, analyzes pipeline data, and optimizes marketing spend to drive revenue.

AI & Machine LearningEnterprise SoftwareMarketing TechSaaSSales TechLondon, GB

Matt Brown(Founder)inVasi Coscotin(Founder)inJonty Knox(Founder)in

Co-investorsY CombinatorCocoaCrane Venture PartnersLatam Venture CapitalSequoia Capital

DeepTech Recyclingdeeptech-recycling.co.ukin𝕏

A plastic chemical recycling company specializing in advanced recycling technology and plant operations for the circular economy sector.

Circular EconomyCleantechDeep TechNew MaterialsSwindon, GB

Marvine Besong(CEO)in

BoardSimon Ashby-Rudd(Chair)

Co-investorsEMV Capital

Docbotdocbot.coSeedAcquired

Docbot developed AI-powered software for gastroenterology, using computer vision to detect polyps and assist diagnosis during endoscopy and colonoscopy procedures.

ConsumerGamingHealthtechLos Angeles, US

Tyler Dao(Founder)inWilliam Karnes(Founder)inAndrew Ninh(Founder)in

Co-investorsBold Capital PartnersBoutique Venture PartnersY CombinatorApplied AngelsBankia Fintech VentureCollaborative Fund+5 more

Draprdrapr.cominSeedAcquired

Drapr provides virtual try-on technology for clothing that enables shoppers to preview apparel online and helps brands increase their digital sales.

ConsumerE-commerceSaaSSan Francisco, US

David Pastewka(Founder)inRichard Berwick(Founder)inWill Drevno(Founder)in

Co-investorsCabra VCNeer Venture PartnersSmart Partnership CapitalY CombinatorBamboo Capital PartnersBoost VC+2 more

Flow Engineeringflowengineering.comin𝕏

Flow is a hardware development platform that uses AI to help engineering teams keep requirements, architecture, and verification aligned across complex vehicle programs.

Advanced ManufacturingAI & Machine LearningDeveloper Tools

Pari Singh(Founder)in

Co-investorsAir Street CapitalBackedDeep Science VenturesSequoia CapitalAtreides ManagementEntrepreneur First+3 more

Greenpixiegreenpixie.comin

Greenpixie provides emissions measurement and cloud sustainability services to engineering teams, helping them reduce waste and improve efficiency in cloud operations.

AI & Machine LearningCleantechClimate TechCloud Computing

John Ridd(Founder)in

Co-investorsAscensionGreen Angel VenturesOctopus VenturesBeringea

Home Daohome-dao.comin𝕏

homeDAO is a residential accelerator program in Oxford that provides free accommodation, workspace, and $350k SAFE funding to founders building early-stage companies.

EdTechFuture of WorkOxford, GB

Co-investorsPragma Ventures

Instapath Inc.instapathbio.comin𝕏Seed · Sep 2019

Instapath develops rapid digital pathology microscopy platforms that enable cancer diagnosis from tissue samples in minutes rather than days.

BiotechDeep TechHealthtechMedical DevicesHouston, US

Mei Wang(Founder)inQuincy Brown(Founder)inDavid Tulman(Founder)in

Co-investorsDraper AssociatesY CombinatorVenture Investment Associates

Intellineintelline.cainSeed

Intelline develops CAVIE modular power systems for industrial applications, offering scalable distributed power generation with fuel-agnostic capability and up to 40% improved fuel efficiency.

Advanced ManufacturingCleantechClimate TechEnergyHardwareRoboticsWaterloo, CA

Kyle Faller(Founder)inChris Mathew(Founder)in

Co-investorsPioneerY CombinatorAgrolimen VenturesBamboo Capital PartnersLLLP

Isablisabl.ioin𝕏Seed

Isabl develops whole genome and transcriptome sequencing technology for cancer diagnosis, delivering comprehensive genomic profiling and treatment options to physicians and research teams.

BiotechDigital HealthHealthtechMedical DevicesNew York City, US

Juan Medina(CTO and Technical Co-founder)inAndrew Kung(MD PhD, Medical Co-Founder)inElli Papaemmanuil(PhD, CEO and Scientific Co-founder)in

Co-investorsY CombinatorBoxOne VenturesTwo Sigma VenturesEvolution VC PartnersSand Hill AngelsAmino Capital

Jenfijenfi.comin𝕏Seed

Jenfi offers revenue-based financing to digital businesses across Asia, tying repayment obligations to customer revenue.

FintechSingapore, SG

Jeffrey Liu(Founder)inJustin Louie(Founder)inJeffrey Liu Justin Louie(Founder)

Co-investorsICU VenturesITERATIVEMonk's Hill VenturesTaurus VenturesVentureSouqY Combinator+9 more

Lamar Healthlamarhealth.cominSeed

Lamar Health provides workflow automation software for specialty pharmacies and infusion organizations, enabling teams to manage prior authorization processes and patient access workflows.

AI & Machine LearningHealthtechMedia & EntertainmentSaaSSan Francisco, US

Eesha Sharma(Founder)in

Co-investorsDniproHealthy VenturesPenny Jar Capital VentureY CombinatorFlex Capital PartnersFlexcap Ventures+5 more

Luminateluminatemed.comin𝕏Seed

Luminate develops medical device technology to address chemotherapy side effects, particularly hair loss and peripheral neuropathy, for oncology patients and healthcare providers.

BiotechDigital HealthHealthtechMedical DevicesGalway, US

Aaron Hannon(Founder)inBarbara Oliveira(Founder)inProf. Martin O'Halloran(Co-Founder)JAMES EVERINGHAM(Executive Officer, Director)Eldad Livni(Founder)Leonid Belkind(Founder)

Co-investorsSciFoundersY Combinator8VCArtis VenturesAtlantic Bridge VenturesFaber+13 more

Lunasondelunasonde.comin𝕏Jun 2019

Lunasonde develops aerial georadiotomography (aGRT) technology that uses low-frequency radar to create 3D compositional images of the subsurface from aircraft, helicopters, drones, and balloons.

AgTechCleantechClimate TechDeep TechEnergyCortaro, US

Jeremiah Pate(Executive Officer, Director, Promoter)inHILLARY PATE(Executive Officer)

Co-investorsActuate VenturesBantam GroupDrive CapitalKluz VenturesPure VenturesTechstars+2 more

OneLoginonelogin.comin𝕏

OneLogin provides cloud-based identity and access management (CIAM) solutions that enable organizations to securely manage user authentication and application access across their enterprise infrastructure.

Cloud ComputingCybersecurityEnterprise Software

Christian Pedersen(Founder)Thomas Pedersen(Founder)

Co-investorsCRV (Charles River Ventures)Kleiner PerkinsScale Venture Partners

OpenAIopenai.comin𝕏

OpenAI is an AI research and deployment company focused on developing artificial general intelligence (AGI) with emphasis on safety and beneficial outcomes for humanity.

AI & Machine LearningCloud ComputingEnterprise SoftwareSan Francisco, US

Sam Altman(Founder)Elon Musk(Founder)inGreg Brockman(Founder)inIlya Sutskever(Founder)inWojciech Zaremba(Founder)inJohn Schulman(Founder)

Co-investors7BC Venture CapitalA-Rod CorpA.Capital VenturesA'Z AngelsAdvent InternationalAliya Capital Partners+98 more

Percept.AIpercept.aiinSeedacquired by Atlassian

Percept.AI builds AI systems that handle customer support interactions for businesses, using natural language processing to improve support team productivity and responsiveness.

AI & Machine LearningEnterprise SoftwareSaaSSan Francisco, US

Joe (Zhou) Sha(Founder)inDeyang (Derek) Zhao(Founder)inShuo Han(Founder)in

Co-investorsIncubate USY CombinatorAmino CapitalBuilders VCCherubic VenturesCyphr+5 more

Phoenix Tailingsphoenixtailings.comin𝕏Jul 2021

Phoenix Tailings develops clean technology for rare earth element refining in the United States.

Advanced ManufacturingCleantechClimate TechEnergyFintechNew MaterialsBoston, US

Thomas Villalón(Chief Technology Officer & Co-Founder)Anthony Balladon(Founder)inMichelle Chao(Founder)inNick Myers(Chief Executive Officer & Co-Founder)inNicholas Myers(Founder)Tomas Villalon(Founder)

Co-investorsBantam GroupBMW i VenturesCoalitionGeodesic CapitalIn-Q-TelMPower+13 more

Sealseal.runinSeed

Seal provides a software platform that replaces paper and legacy systems for managing GxP (good manufacturing and laboratory practices) work, with built-in AI assistance for process improvement, validation tracking, and compliance records in pharmaceutical and life sciences manufacturing.

AI & Machine LearningBiotechEnterprise SoftwareHealthtechSaaSLondon, GB

Will Moss(Founder)inJonathan Dench(Founder)in

Co-investorsEntrepreneur FirstJude GomilaY CombinatorAllison Pickens VenturesAndreessen HorowitzASDF Ventures+6 more

SepPure Technologiesseppure.comin

SepPure Technologies develops nano-filtration membrane technology that replaces conventional energy-intensive chemical separation processes, reducing solvent use, energy consumption, and emissions.

Advanced ManufacturingCleantechClimate TechDeep TechNew MaterialsSingapore, SG

Mohammad Farahani(CEO)inAmir Hooshang Taheri(Founding CTO)in

Co-investors500 GlobalEntrepreneur FirstUntroD CapitalSEEDS CapitalSOSV

SpaceRydespaceryde.comin𝕏SeedDefunct

SpaceRyde develops reusable spacecraft that deploy via stratospheric balloon and establish an orbital network to perform cargo transport and on-demand in-space services such as refueling, deep-space missions, and debris removal.

Advanced ManufacturingHardwareSpace TechSan Francisco, US

Sohrab Haghighat(Founder)in

Co-investorsBackbone AngelsPi CampusY CombinatorAutomation VenturesChainFund CapitalLiquid Ventures+5 more

Techwolf Skills intelligence platformtechwolf.ai

TechWolf builds AI-driven skills intelligence software that helps enterprises unlock and manage talent based on skills rather than job titles or credentials.

AI & Machine LearningEnterprise SoftwareHR TechSaaSGhent, BE

Mikael Wornoo(Founder)inAndreas De Neve(Founder)inJeroen Van Hautte(Founder)inYasamin Karimi(Chief Product Officer)in

Co-investors20VCAcadian Ventures Management, LlcFELIX CAPITALNotion CapitalPMVSemperVirens Venture Capital+4 more

Tessiantessian.com𝕏

Tessian provides AI-powered email security solutions that detect and prevent email-based cyberattacks and data loss for enterprises.

AI & Machine LearningCybersecurityEnterprise Software

Tim Sadler(Founder)inEdward Bishop(Founder)inEd Bishop(Founder)Thomas Adams(Founder)Tom Adams(Founder)

Co-investorsAccelBalderton CapitalCrane Venture PartnersForgePoint CapitalLocalGlobeMarch Capital Partners+9 more

Trexo Roboticstrexorobotics.comin𝕏Seed

Trexo develops a robotic device that enables children with cerebral palsy and other mobility disabilities to walk independently at home.

HealthtechMedical DevicesRoboticsToronto, CA

Manmeet Maggu(Founder)inRahul Udasi(Founder)in

Co-investorsFoundersFoundersX VenturesGeekdomJoyance Partnerskineo financeSocial Starts+9 more

twoplus fertilitytwoplusfertility.cominSeed

Two Plus Fertility is a fertility and reproductive health service or platform.

Digital HealthDirect to ConsumerFemTechHealthtechMedical DevicesWellness & FitnessSingapore, SG

Prusothman Raja(Founder)inBenjamin Tee(Founder)in

Co-investorsAnthro VenturesGolden Gate VenturesKube VCY CombinatorBamboo Capital PartnersJosh Hannah+4 more

Unimaunimadx.com𝕏SeedDefunct

Unima makes portable diagnostic tests that deliver disease identification at the point of care within 15 minutes at low cost, enabling rapid detection and monitoring of infectious diseases.

BiotechHealthtechMedical DevicesZapopan, MX

Rodrigo Nuno(Founder)inMaria Laura Mendoza(Founder)inAlejandro Nuño Ayala(Founder)inLaura Mendoza(Founder)

Co-investorsY CombinatorAgrolimen VenturesAJGAvalancha VenturesIDrive VenturesInvesto Capital+2 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

AegiqAIWorkifyBlinkBraveCognismGluwaIntec TelecomloveholidaysMessiumOkloOverwolfUmantisVSIMZendesk

Exits · 4

4 acquisitions · showing 2

Atomic Alchemyacq. by OkloPercept.AIacq. by Atlassian

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Thomas James made?
Thomas James has 48 tracked investments, 4 of which have exited.
What stage does Thomas James invest at?
Thomas James invests at the Pre-Seed, Seed, Series A stages.
What sectors does Thomas James focus on?
Thomas James focuses on Advanced Manufacturing, AI & Machine Learning, Cleantech, Climate Tech, Consumer, Cybersecurity, Deep Tech, Enterprise Software, Fintech, Healthtech, New Materials, Quantum Computing, SaaS.
Who does Thomas James co-invest with?
Thomas James most often shares deals with Bantam Group, Entrepreneur First, In-Q-Tel, among 71 tracked co-investors.

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