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BoxOne Ventures

Venture capital

Montréal · Pre-Seed–Series A · 9 people tracked

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Investment thesis

BoxOne Ventures focuses on backing passionate, emerging talent at an early stage, aiming to supercharge founders to maximize their impact and potential. Its areas of interest span biotechnology, the future of food, markets, longevity, intelligence (AI), and clean energy, with a broad emphasis on technologies that improve quality of life.

Source: firm website, verified Aug 3, 2026.

Stage
Pre-Seed–Series A
Check
$500K
HQ
Montréal, CA
Leads rounds
Leads
Instruments
Equity
Founded
2018
Tracked investments
175

Team · 9 people

from the firm's website & public directories
Mike· AI and Engineering Lead

What they invest in

from 57 of 175 portfolio companies

Biotech ×25AI & Machine Learning ×23Healthtech ×21Deep Tech ×14Medical Devices ×11Data & Infrastructure ×8SaaS ×8Hardware ×6

HQs:United States×19Canada×14United Kingdom×1

Investments · 175 tracked

founders shown can be your intro path
Isablisabl.infoin𝕏✓ verified

Isabl develops genomic sequencing technology for cancer diagnosis, enabling whole genome and transcriptome testing in clinically relevant timeframes to provide comprehensive treatment options.

BiotechDigital HealthMedical Devices

Abalone Bioabalonebio.comin𝕏

Abalone Bio develops target-activating antibodies for difficult-to-drug disease targets by combining engineered biology with machine learning.

AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US

Richard Yu(Founder)inGustavo Pesce(Founder)in

Aggeneaggene.ca
AI agent building platform
AI agriculture and forestry platform
AI photocatalysts for water purification
AI-based radiofrequency systems
AI-driven business decision optimization
Alectifyalectify.ai
Algae-based fuel from CO2
Altiroenergyaltiroenergy.com

Altiro Energy develops an iron-based energy storage system that stores renewable or excess energy as reusable CO2-free iron fuel and later releases it as on-demand heat or power, producing rust that is recharged for the next cycle.

CleantechClimate TechEnergy

Angstrom Insightsangstrom-insights.ai
Animal-free milk producer
Antibody-drug conjugate optimization
Arpeggio Bioarpeggiobio.comin𝕏

Arpeggio Bio develops pharmaceutical drugs that target transcription factors using artificial intelligence and RNA-sequencing technology, with lead programs in development for melanoma treatment and rare disease applications.

BiotechHealthtechBoulder, US

Joey Azofeifa(Founder)inAmit Mehta(Director)Laura Norris(Executive Officer, Director)Joseph G. Azofeifa(Executive Officer, Director)Timothy Read(Executive Officer, Director)Eric Martin(Executive Officer)

Avian and human antibody discovery
AVIEWaviewint.comin𝕏

Aview provides multimedia translation and dubbing services to help content creators and entertainers expand their audience internationally across social media platforms.

AI & Machine LearningCreator EconomyMarketing TechMedia & EntertainmentAncaster, CA

Axonis Therapeuticsaxonis.usin

Axonis Therapeutics develops medicines targeting KCC2 to restore inhibition in the brain, with a focus on treating neurological disorders including epilepsy and pain.

BiotechMedical DevicesBoston, US

Shane Hegarty(Executive Officer)Jeffrey Imbaro(Executive Officer)Joanna Stanicka(Executive Officer, Director)

BoardCorey . Goodman(Director)Jonathan Leff(Director)Raymond J. Kelleher(Director)

Besidehabitatbesidehabitat.comin

BESIDE Habitat operates architecturally designed cabins for short stays in a preserved natural park setting, offering guests activities such as trail running, wildlife observation, sauna, snowshoeing and cross-country skiing.

ConsumerTravel & HospitalityRawdon, CA

Bioinformatics workflow management
Biological network medicine engineering
BioLoomicsin

Boulder, US

Nicholas Saccomano(Director)Douglas A Chapnick(85 FORREST LANE BOULDER, CO 80302)Joel Dudley(Director)

Biomanufacturing genome digitalization
Biopharma collaboration management
Bioprinting 3D tissue systems
Bitcoin cashback shopping platform
Blank Bioblank.bioin𝕏

Blank Bio develops RNA foundation models for precision oncology, helping pharmaceutical companies identify the right patients for clinical trials and predict disease progression using bulk RNA-seq data.

AI & Machine LearningBiotechHealthtechSan Francisco, US

Jonny Hsu(Founder)inPhilip Fradkin(Founder)inIan Shi(Founder)in

Blockchain betting exchange
Botpressbotpress.com
Cell-free biocatalyst
Cell-therapy modular assembly platform
Clinical trial patient identification
Coinmilescoinmiles.io
Colabracolabra.app

Colabra provides an AI workspace for M&A due diligence that converts sell-side document dumps into a clause-linked risk register, entity map, and gap analysis.

AI & Machine LearningFintechSaaS

Compliance transformation automation
Comprehensive workforce database
Contxtfulcontxtful.com

Contxtful offers Receptiv, a product that scores each programmatic bid request in real time for user receptivity and bundles high-scoring impressions into a Deal ID synced to a buyer's DSP seat.

AdTechAI & Machine Learning

Covariancecovariance.aiin

Covariance offers an AI product, Conrad, that answers questions about the US consumer economy — category and brand trends, competitor market share, and audience personas — grounded in purchase data from millions of households and merchants.

AI & Machine LearningData & InfrastructureMarketing Tech

Custom protein-producing fruit flies
Cytotronicscytotronics.comin

Cytotronics develops Pixel, a semiconductor-to-live-cell interface platform that enables real-time monitoring of multiple cellular properties for drug discovery and cell biology research.

Deep TechMedical DevicesBoston, US

Jeffrey Abbott(Executive Officer, Director)Wenxuan Wu(Executive Officer, Director)

BoardSameer Rohatgi(Director)Jenna Abelli(Director)Douglas Kahn(Director)

Data-centric problem-solving platform
Decentralized allergy testing
Decentralized dialysis provider
Deep learning drug discovery
Digital electrical infrastructure company
Digital employee benefits wallet
Dispersadispersa.cain

Dispersa manufactures biosurfactants derived entirely from food waste, offering a platform of biodegradable bioproducts such as its flagship PuraSurf M ingredient for home, industrial, and institutional (HI&I) formulations.

BiotechCircular EconomyNew Materials

Drug resistance and treatment enhancement
Drugbankdrugbank.com
DTC e-commerce brand scaling platform
Dynomicsdynomics.com
Elementaielementai.com
Encellinencellin.comin𝕏

Encellin develops next-generation therapies for patients with chronic unmet clinical needs, using technology originating from Dr.

BiotechDeep TechHealthtechMedical DevicesSan Francisco, US

Tejal Desai(Technology Expert, Founder)Ronald Martell(Strategic Advisor, Founder)Crystal Nyitray(Executive Officer, Director, Promoter)Grace Wei(Executive Officer, Director, Promoter)Maria del Consuelo Valverde(Director)

Endocrine disorder therapy developer
Endofoldendofold.bio
EV charging infrastructure
FabricNanofabricnano.comin

Claymont, US

Siraj Khaliq(Director)Grant Aarons(Executive Officer, Director, Promoter)Ferdinando Randisi(Director)Robert Kniaz(Director)

Fathomfathom.video

Fathom provides a platform that records and analyzes customer conversations, internal syncs, and strategy calls to give teams a shared view of information and identify patterns.

Enterprise SoftwareSaaS

FightCampjoinfightcamp.comin𝕏

FightCamp provides home boxing and martial arts training equipment and coaching, combining a hardware console with trackers and wraps alongside a structured digital training platform.

ConsumerGamingHardwareLos Angeles, US

Khalil Zahar(Founder/CEO)inPatrick Chandler(Founder/CMO)inAlexandre Marcotte(Founder/CTO)

Frequently asked questions

What stage does BoxOne Ventures invest at?
BoxOne Ventures invests at the Pre-Seed, Seed, Series A stages.
What is BoxOne Ventures's typical check size?
BoxOne Ventures typically writes checks of $500K.
What sectors does BoxOne Ventures focus on?
BoxOne Ventures focuses on AI & Machine Learning, Biotech, Cleantech, Energy, FoodTech, Healthtech, Longevity.
Where is BoxOne Ventures located?
BoxOne Ventures is headquartered in Montréal, CA.
Does BoxOne Ventures lead rounds?
Yes, BoxOne Ventures leads investment rounds.

Images

BoxOne Ventures photoBoxOne Ventures photo

Co-investors · 2

Entrepreneur First

Entrepreneur First (EF) is a talent investor that helps individuals build and launch startups, providing support such as US visa guidance, office space, fundraising preparation, and investor introductions culminating in a San Francisco Demo Day.

$1M – $7M
Sofinnova Ventures

Sofinnova is an investment firm that partners with biotech companies from inception through growth, supporting drug development, the regulatory process, company building, and IPO.

Both backed · 1
$100K – $15M

Firms observed investing alongside BoxOne Ventures, from public investor directories. Shared companies are the overlap with BoxOne Ventures's recorded portfolio.

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