Bison Ventures
Venture capitalActively deployingSeattle · Seed–Series A · 7 people tracked
Also known as BISON VENTURES MANAGEMENT COMPANY, LLC
Investment thesis
Bison Ventures backs frontier technology companies using science-based and deep technology to tackle the world's most pressing challenges, from combating climate change to curing disease to meeting soaring compute demand. The firm believes these problems require bold, deeply technical solutions that work at massive scale, arguing that software alone is insufficient. It focuses on three areas: AI in the physical world (robotics and AI-first tools across manufacturing, agriculture, energy, construction, and logistics), techbio (engineering biology through high-throughput experimentation and data), and climate and sustainability (AI, automation, new materials, and biotech for climate adaptation and mitigation). It supports contrarian founders building category-defining companies.
Source: firm website, verified Aug 7, 2026.
Team · 7 people
from the firm's website & public directories
What they invest in
from 12 of 29 portfolio companiesAI & Machine Learning ×8Biotech ×3Robotics ×3AgTech ×2Deep Tech ×2Developer Tools ×2Hardware ×2Medical Devices ×2
HQs:United States×9
Investments · 29 tracked
founders shown can be your intro pathBoston, US
Board seatTom Biegala· per SEC Form D · $25M raise · filed Mar 2023
San Francisco, US
Noah Weber(Director)Rui Aguiar(Executive Officer, Director)Caleb Appleton(Director)Davis Treybig(Director)
Board seatCaleb Appleton· per SEC Form D
Great Sky develops physics-based computational intelligence and AI systems built from foundational research.
AI & Machine LearningDeep TechHardwareBoulder, US
Jeffrey Shainline(Executive Officer, Director)inTom Biegala(Director)Mark Wade(Director)
Board seatTom Biegala· per SEC Form D
Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.
AI & Machine LearningBiotechLongevityMedical DevicesRedwood City, US
Jeremy O'Connell, PhD(Chief Scientific Officer and Co-Founder)Hanadie Yousef, PhD(Executive Advisor and Co-Founder)Steven James(Director)inStephen Juelsgaard(Director)inHanadie Yousef(Executive Officer, Director)Laura Lande-Diner(Director)in
Board seatBen Hemani· per SEC Form D
Creating the ML-enabled intelligence platform for healthcare
San Francisco, US
Andrew Pannu(Executive Officer, Director)Caleb Appleton(Director)Mark Jacobstein(Director)
Board seatCaleb Appleton· per SEC Form D · $7.9M raise · filed Oct 2025
Healthtech
John DeLoche(Director)Riaz Valani(Director)Jeremy Alberga(Resigned as an executive officer in April 2015.)Nathan D Wolfe(Executive Officer, Director)Robert Mann(Executive Officer, Director)
Ark provides a customizable digital platform for venture capital and private equity firms to manage investor communications, performance reporting, and document sharing with their limited partners.
Enterprise SoftwareFintechSaaS
Bonsai Robotics develops software that manages autonomous fleets for agricultural and construction operations.
AgTechAI & Machine LearningRobotics
AI-driven hardware design and simulation
Cadstrom provides automated schematic and PCB validation software that catches design errors traditional ERC flows and manual reviews miss, producing structured validation reports before boards go to fabrication.
AI & Machine LearningDeveloper ToolsHardware
Margot(Sets the technical vision (technical lead/co-founder))Scott
Ubiquitous robotics and autonomy to solve challenges in the physical world
Using AI to improve behavioral healthcare
Grid Aero develops autonomous aircraft and flight autonomy systems focused on contested logistics and defense sustainment for the U.S.
Defense TechLogistics & Supply ChainRoboticsPalo Alto, US
Brandon Florian(Executive Officer, Director)Alex Kroll(Executive Officer)Chinmay Patel(Executive Officer)Arthur Paul Dubois Taine(Founder / Aerospace Engineering Leader)
Physical AI for the operating room
InnerPlant develops living sensor technology that enables farmers to detect plant stress in real-time, allowing targeted application of treatments to reduce chemical use and increase crop yields.
AgTechBiotechIoTCalifornia, US
RodinGary Schaefer(Chief Commercial Officer)inShely Aronov(Executive Officer, Director)
Using AI to unlock the power of stem cells
Tackling complex diseases using computational genetics
Semaphor Surgical develops foundational AI infrastructure for surgical systems, providing perception, planning, and decision-making capabilities that enable on-device intelligence for autonomous surgical applications.
AI & Machine LearningMedical DevicesRoboticsBaltimore, US
Tito Porras(Chief Executive Officer)inMathias Unberath(Chief Technology Officer)inAxel Krieger(Chief Robotics Officer)in
Frontier AI research and product company
Thinking Machines Lab is an AI research and product company building systems for human-AI collaboration with emphasis on customization, safety, and accessibility.
AI & Machine Learning
Vivodyne is a bio-AI company that develops lab-grown human tissues and robotic systems to generate causal biological data for therapeutic development.
AI & Machine LearningBiotechDeep TechBrisbane, US
Julie O'Shaughnessy(Director)Andrei Georgescu(Executive Officer, Director)Quinten Stevens(Director)Alex Andrianopolous(Director)Dongeun Huh(Executive Officer, Director)ALEX ANDRIANOPOULOS(Director)
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- What stage does Bison Ventures invest at?
- Bison Ventures invests at the Seed, Series A stages.
- What sectors does Bison Ventures focus on?
- Bison Ventures focuses on Advanced Manufacturing, AgTech, AI & Machine Learning, Biotech, Cleantech, Climate Tech, Deep Tech, Energy, Healthtech, Logistics & Supply Chain, New Materials, Robotics.
- Where is Bison Ventures located?
- Bison Ventures is headquartered in Seattle, US.
Media · Podcasts & interviews
featuring the teamHow to Choose Prudent Investments with Ben Hemani of Bison Ventures
The Building Biotechs Podcast · Ben Hemani
Images
Co-investors · 2
Alumni Ventures (AV) is a venture firm that gives accredited individual investors access to professionally managed, diversified venture portfolios by co-investing alongside leading lead VC firms. It offers annual funds, syndicate deal-by-deal investing, and various investor clubs.
Mubadala is a government-owned investment firm that actively develops and diversifies Abu Dhabi's economy away from oil, operating as both a sovereign investor and domestic industrial development engine rather than focusing primarily on financial returns like traditional sovereign funds. Through Mubadala Capital, it combines sovereign anchor capital with third-party institutional capital to operate as a competitive, fee-earning investment manager across private equity, venture capital, and private credit—an uncommon model where a sovereign wealth affiliate manages external investor money alongside its own.
Firms observed investing alongside Bison Ventures, from public investor directories. Shared companies are the overlap with Bison Ventures's recorded portfolio.
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