Bison Ventures
Venture capitalActively deployingSeattle · Seed–Series A · 6 people tracked
Also known as BISON VENTURES MANAGEMENT COMPANY, LLC
Investment thesis
Bison Ventures backs frontier technology companies using science-based and deep technology to tackle the world's most pressing challenges, from combating climate change to curing disease to meeting soaring compute demand. The firm believes these problems require bold, deeply technical solutions that work at massive scale, arguing that software alone is insufficient. It focuses on three areas: AI in the physical world (robotics and AI-first tools across manufacturing, agriculture, energy, construction, and logistics), techbio (engineering biology through high-throughput experimentation and data), and climate and sustainability (AI, automation, new materials, and biotech for climate adaptation and mitigation). It supports contrarian founders building category-defining companies.
Source: firm website, verified Aug 25, 2026.
Team · 6 people
from the firm's website & public directories
What they invest in
from 18 of 25 portfolio companiesAI & Machine Learning ×13Biotech ×6Deep Tech ×4Developer Tools ×3Enterprise Software ×3Robotics ×3AgTech ×2Data & Infrastructure ×2
HQs:United States×13Canada×1
Who they back
founder profiles across 10 portfolio companiesFounding team size:solo founder×42 founders×23 founders×24+ founders×2
Investments · 25 tracked
founders shown can be your intro pathBy year:2026 · 22025 · 42024 · 22023 · 19 dated
Allonnia applies industrial biology—screening microbes and engineered proteins that interact with metals—to recover copper, nickel, and rare earths from ore and mine waste streams like coal ash, tailings, and acid mine drainage.
BiotechCleantechNew MaterialsBoston, US
Nicole Richards(CEO)Kent Sorenson(Chief Technology Officer)inChuck(Executive)inPamela(Head of Human Resources)inHugh(Financial Leadership)in
Board seatTom Biegala· per SEC Form D
Co-investorsFerment Studio
Cosmon builds Nexus, an AI agent for hardware engineers that automates CAD, simulation (CAE), and PLM tasks such as design checking, drawing generation, and simulation setup.
Advanced ManufacturingAI & Machine LearningEnterprise SoftwareSan Francisco, US
Rui Aguiar(Executive Officer, Director)Noah Weber(Director)
BoardDavis Treybig(Director)in
Board seatCaleb Appleton· per SEC Form D
Co-investorsInnovation Endeavors
Great Sky develops physics-based computational intelligence and AI systems built from foundational research.
AI & Machine LearningDeep TechHardwareBoulder, US
Jeffrey Shainline(Executive Officer, Director)inMark Wade(Director)in
Board seatTom Biegala· per SEC Form D
Co-investorsMatchstick VenturesMythos Ventures Management, LlcRange VCService Provider CapitalWireframe Ventures
Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.
AI & Machine LearningBiotechLongevityMedical DevicesRedwood City, US
Jeremy O'Connell, PhD(Chief Scientific Officer and Co-Founder)Hanadie Yousef, PhD(Executive Advisor and Co-Founder)Hanadie Yousef(Executive Officer, Director)Jeremy O'Connell(Director)Dr. Hanadie Yousef(Founder)in
Board seatBen Hemani· per SEC Form D
Co-investorsBascom VenturesCompoundHarmonix FundHorizons VenturesManta Ray VenturesOpen Field Capital+3 more
Sleuth provides evidence-backed answers for biopharma decision-making, built on a knowledge graph that maps over a billion relationships across biology, clinical evidence, competitive dynamics, and deal history.
AI & Machine LearningBiotechData & InfrastructureFintechSan Francisco, US
Andrew Pannu(Executive Officer, Director)
BoardMark Jacobstein(Director)
Board seatCaleb Appleton· per SEC Form D
Co-investorsHAWKTAILAtria Ventures
Ark provides a customizable digital platform for venture capital and private equity firms to manage investor communications, performance reporting, and document sharing with their limited partners.
Enterprise SoftwareFintechSaaS
Co-investorsAcies InvestmentsAloft VCAlta PartnersAmity VenturesArtis VenturesAsymmetric Capital Partners+21 more
Bonsai Robotics develops autonomy technology and equipment, including its Amiga lineup powered by Bonsai Intelligence, to automate off-road jobs for operations ranging from small businesses to large companies.
AgTechAI & Machine LearningRobotics
Co-investorsAcre Venture PartnersBetter Food VenturesCongruent VenturesSerra VenturesSoundproof VenturesThe E14 Fund+2 more
Cadstrom provides automated schematic and PCB validation software that catches design errors traditional ERC flows and manual reviews miss, producing structured validation reports before boards go to fabrication.
AI & Machine LearningDeveloper ToolsHardwareMontréal, CA
Margot(Sets the technical vision (technical lead/co-founder))inMargot Blouin(Founder)
Co-investorsAllen Institute for AI (AI2) Incubator
Ubiquitous robotics and autonomy to solve challenges in the physical world
Redefining the future of human-robot interaction.
Brad Porter(Founder & CEO)inJane Mooney(Co-founder & VP, Strategy and Finance)inSteph Tryphonas(Co-founder)in
Co-investorsCalibrate VenturesMVP VenturesRitual CapitalSequoia Capital1984 Ventures Management, LlcBezos Expeditions+4 more
Frontera Health builds AI tools that help clinicians write behavioral health assessments and diagnostic reports for children with autism and related disorders, cutting documentation time and reducing waitlists.
AI & Machine LearningDigital HealthHealthtechDenver, US
Amol Deshpande(Executive Officer, Director)
BoardGalym Imanbayev(Director)inBilal Zuberi(Director)in
Co-investorsInspired CapitalLightspeed Venture PartnersRed Glass Ventures
Grid develops uncrewed, long-range cargo aircraft ("Lifter") that carry heavy payloads over thousands of miles, operated as a distributed, autonomous mesh network managed by small ground teams.
Defense TechLogistics & Supply ChainRoboticsPalo Alto, US
Alex Kroll(Executive Officer)Chinmay Patel(Executive Officer)inArthur Paul Dubois Taine(Founder / Aerospace Engineering Leader)Arthur DuboisinBrandon Florian(Executive Officer, Director)in
Co-investorsCalibrate VenturesCommonweal VenturesGeodesic CapitalAlumni VenturesUbiquity Ventures
Physical AI for the operating room
InnerPlant develops living sensor technology that enables farmers to detect plant stress in real-time, allowing targeted application of treatments to reduce chemical use and increase crop yields.
AgTechBiotechIoTCalifornia, US
RodinShely Aronov(Executive Officer, Director)Gary Schaefer(Chief Commercial Officer)in
Co-investorsCultiv8 Funds ManagementKokopelli CapitalMS&AD VenturesPlum Alley InvestmentsSystemiq CapitalTAU Ventures+3 more
Using AI to unlock the power of stem cells
Logic is a production AI platform where teams write a natural language spec that is turned into a spec-driven agent with typed REST APIs, auto-generated tests, version control, and multi-model routing across providers like GPT, Claude, and Gemini.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSaaSSeattle, US
Steve Krenzel(Founder)inJess Garms(Founder)in
Co-investorsAudacious8VCAlumni VenturesGeneral CatalystKhosla VenturesPillar VC+1 more
Tackling complex diseases using computational genetics
Passkey operates Locksmith, a computational platform that uses human genetics, biology, and pharmacology to identify synergistic drug combinations from approved and late-stage drugs, allowing existing assets to be repurposed for new indications.
AI & Machine LearningBiotechDeep Tech
Co-investorsBreakout VenturesWireframe Ventures
Router Protocol operates an open, permissionless cross-chain swap network that connects solvers, DEXs, and bridges into a unified system for executing low-slippage swaps across blockchains.
Crypto & Web3Data & InfrastructureDeveloper Tools
Ramani Ramachandran(Founder & CEO)
Co-investorsBitDAOCoinbase VenturesMantle NetworkMapleblock CapitalO1exTDeFi+8 more
Semaphor Surgical develops foundational AI infrastructure for surgical systems, providing perception, planning, and decision-making capabilities that enable on-device intelligence for autonomous surgical applications.
AI & Machine LearningMedical DevicesRoboticsBaltimore, US
Tito Porras(Chief Executive Officer)inMathias Unberath(Chief Technology Officer)inAxel Krieger(Chief Robotics Officer)in
Co-investorsFlare Capital PartnersPage One Ventures
Frontier AI research and product company
Thinking Machines Lab is an AI research and product company building systems for human-AI collaboration with emphasis on customization, safety, and accessibility.
AI & Machine LearningSan Francisco, US
Mira Murati(Co-founder)inBarret Zoph(Co-founder)inLilian Weng(Co-founder)inAndrew Tulloch(Co-founder)inLuke Metz(Co-founder)inPhuong Nga Nguyen(Founder)
Co-investorsAccelAndreessen HorowitzFactorial FundsGV (Google Ventures)Juniper Ventures Management, LlcOwl Ventures+4 more
Vivodyne is a bio-AI company that develops lab-grown human tissues and robotic systems to generate causal biological data for therapeutic development.
AI & Machine LearningBiotechDeep TechBrisbane, US
Andrei Georgescu(Executive Officer, Director)Dongeun Huh(Executive Officer, Director)Andrei Georgescu, Ph.D.(Founder)in
BoardQuinten Stevens(Director)Alex Andrianopolous(Director)Alex Morgan(Director)in
Co-investorsKairos Venture Investments, LlcKhosla VenturesFortius VenturesMBX Capital
Zyphra is an AI research company building open foundation models based on novel architectures trained on heterogeneous compute, with a focus on intelligence efficiency and silicon performance.
AI & Machine LearningCloud ComputingDeep TechSan Francisco, US
Tomás Figliolia(Founder)
Co-investorsDefined VCFuture VenturesGaia VenturesMetaplanet
Portfolio news
latest coverage across their companiesLogic · investing.com · Aug 11, 2026
Thinking Machines Lab · cryptobriefing.com · Jul 16, 2026
Juvena Therapeutics · newmarketpitch.com · Jul 13, 2026
Zyphra · intellizence.com · May 25, 2026
Great Sky · inforcapital.com · Mar 16, 2026
Grid Aero · aviationtoday.com · Feb 5, 2026
Bonsai Robotics · trysignalbase.com · Nov 20, 2025
Sleuth Insights · intelligence360.news · Nov 3, 2025
Frequently asked questions
- How many investments has Bison Ventures made?
- Bison Ventures has 25 tracked investments, including 6 dated in the last 24 months.
- What stage does Bison Ventures invest at?
- Bison Ventures invests at the Seed, Series A stages.
- What sectors does Bison Ventures focus on?
- Bison Ventures focuses on Advanced Manufacturing, AgTech, AI & Machine Learning, Biotech, Cleantech, Climate Tech, Deep Tech, Energy, Healthtech, Logistics & Supply Chain, New Materials, Robotics.
- Where is Bison Ventures located?
- Bison Ventures is headquartered in Seattle, US.
- Does Bison Ventures lead rounds?
- Bison Ventures has led 3 of the 4 rounds where its role is on record.
- Who does Bison Ventures co-invest with?
- Bison Ventures most often shares deals with Calibrate Ventures, Kindred Ventures, Page One Ventures, among 101 tracked co-investors.
Media · Podcasts & interviews
featuring the teamHow to Choose Prudent Investments with Ben Hemani of Bison Ventures
The Building Biotechs Podcast · Ben Hemani
Images
Co-investors · 2
Alumni Ventures (AV) is a venture capital firm that co-invests alongside lead VCs in startups, backing founders with capital and access to a large investor and operator community.
Mubadala is a government-owned investment firm that actively develops and diversifies Abu Dhabi's economy away from oil, operating as both a sovereign investor and domestic industrial development engine rather than focusing primarily on financial returns like traditional sovereign funds. Through Mubadala Capital, it combines sovereign anchor capital with third-party institutional capital to operate as a competitive, fee-earning investment manager across private equity, venture capital, and private credit—an uncommon model where a sovereign wealth affiliate manages external investor money alongside its own.
Firms observed investing alongside Bison Ventures, from public investor directories. Shared companies are the overlap with Bison Ventures's recorded portfolio.
Similar investors
Khosla Ventures is a venture capital firm that invests in early-stage companies focused on technology, mobile, and clean energy sectors, including biotechnology applications. The firm provides capital and strategic support to entrepreneurs developing breakthrough technologies across multiple markets.
Unruly Capital is a venture firm that backs founders working on ideas that seem too early or unconventional but are expected to become mainstream within a decade, focusing on frontier technology themes.
Creative Destruction Lab (CDL) is a nonprofit organization that runs an objectives-based mentoring program for seed-stage, science- and technology-based startups, helping founders build massive companies.
BDC Fund Investments is the fund-of-funds arm of BDC Capital that acts as a limited partner, backing emerging and established fund managers who invest in technology-focused Canadian companies.
Everywhere Ventures is an early-stage venture firm, backed by a community of founders and operators as LPs, that writes early checks (including pre-seed) into startups across many sectors and geographies.