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Bison Ventures

Venture capitalActively deploying

San Francisco · 2 people tracked

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Investment thesis

Bison invests in contrarian, science-based deep technology solutions that address humanity's most pressing challenges at massive scale. The firm focuses on three core areas: AI reshaping the physical world through robotics and autonomous systems across manufacturing, agriculture, and logistics; techbio leveraging high-throughput experimentation and biological engineering to solve human health and climate problems; and climate sustainability through companies applying AI, automation, new materials, and biotech to commercial climate adaptation and mitigation. These bold technical innovations, though counterintuitive today, will define new categories and create trillion-dollar opportunities.

Source: firm website, verified Jul 21, 2026.

HQ
San Francisco, US
Tracked investments
2

Team · 2 people

from the firm's website
Ben Hemani· Co-founder, Bison Venturesin

Ben Hemani is an engineer and investor focused on frontier technology companies, with particular interest in AI applications in the physical world. He previously led venture investments at Cascade Asset Management Company (managing Gates Foundation assets) and started his investing career at Braemar Energy Ventures, where he led early investments in climate technology companies. He holds a B.E. and Master of Engineering Management from Dartmouth.

Tom Biegala· Co-founder, Bison Venturesin

Tom Biegala is a frontier technology investor and engineer with two decades of experience across the company lifecycle, from early R&D through IPO. He previously worked at Cascade Asset Management Company managing venture investments for the Gates Foundation and Gates family offices, and earlier held engineering roles at Intel and university spinouts focused on solar technologies. He holds a B.S. in Materials Science and Engineering from Cornell University and an MBA from Northwestern University's Kellogg School of Management.

What they invest in

from 2 of 2 portfolio companies

AI & Machine Learning ×2Biotech ×1Deep Tech ×1Hardware ×1Longevity ×1Medical Devices ×1

HQs:United States×4

Investments · 2 tracked

founders shown can be your intro path
Great Skygreatsky.ai

Great Sky develops physics-based computational intelligence and AI systems built from foundational research. The company targets applications requiring powerful, adaptive, and resource-efficient AI unconstrained by legacy computing infrastructure.

AI & Machine LearningDeep TechHardwareBoulder, US

Gus Swansen(Senior Hardware Systems Engineer)

Juvena Therapeuticsjuvenatherapeutics.comin

Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.

AI & Machine LearningBiotechLongevityMedical Devices

Jeremy O'Connell, PhD(Chief Scientific Officer and Co-Founder)Hanadie Yousef, PhD(Executive Advisor and Co-Founder)

Board seats · per SEC filings · 3

what is this? ⓘ
Great Sky Inc.SEC filing

$6.5M raise · filed Sep 2025 · via Tom Biegala

Juvena Therapeutics, Inc.SEC filing

$41M raise · filed Jul 2025 · via Ben Hemani

Allonnia, LLCSEC filing

$25M raise · filed Mar 2023 · via Tom Biegala

Inferred from directors named on each company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Frequently asked questions

What sectors does Bison Ventures focus on?
Bison Ventures focuses on Advanced Manufacturing, AgTech, AI & Machine Learning, Biotech, Climate Tech, Deep Tech, Energy, Logistics & Supply Chain, Robotics.
Where is Bison Ventures located?
Bison Ventures is headquartered in San Francisco, US.

Images

Bison Ventures photoBison Ventures photo

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