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VTC Ventures

Venture capital

Managed byMiddleland Capital

Roanoke · Pre-Seed–Series A · 3 people tracked

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Investment thesis

VTC Ventures invests at the earliest stages in areas where its LPs — notably Carilion Clinic and Virginia Tech — provide differentiated insight, deliberately avoiding a generalist approach. Roughly 60% of capital targets transformative healthcare (therapeutics, medical devices, diagnostics, health tech) and 40% high-growth technology, including deep tech, dual-use defense, AI, cybersecurity, robotics, and food & agriculture. The firm pairs targeted early investment with substantial institutional support, offering founders access to hospital systems, patient populations, clinical trial infrastructure, university labs, IP, and operator expertise. It prioritizes companies tied to the Virginia Tech–Carilion ecosystem and Southwest Virginia but invests across the US and globally.

Source: firm website, verified Sep 20, 2026.

Stage
Pre-Seed–Series A
Check
$200K – $1M
HQ
Roanoke, Virginia, US
Leads rounds
Leads
Instruments
Equity
Founded
2016
Last 12 months
1 investment
Tracked investments
18

Team · 3 people

from the firm's website & curated & public directories

What they invest in

from 16 of 18 portfolio companies

AI & Machine Learning ×6Biotech ×5Digital Health ×5Medical Devices ×5AgTech ×4Data & Infrastructure ×4Deep Tech ×4Enterprise Software ×4

HQs:United States×12

Who they back

founder profiles across 8 portfolio companies
50%
solo founders
4 of 8 mapped founding teams
30%
repeat founders
of 10 founders with career history

Founding team size:solo founder×42 founders×4

What their founders studiedfrom 10 founders with field-of-study data

Computer Science ×2Engineering ×2

Where their founders worked beforefrom 10 founders with career history

Harvard John A. Paulson School of Engineering and Applied Sciences ×2

Investments · 18 tracked

founders shown can be your intro path

By year:2026 · 12023 · 32020 · 15 dated

Agfundernewsagfundernews.comin𝕏✓ verified

AgFunderNews is a digital media outlet and news platform that publishes daily content analyzing trends in foodtech, agtech, and climate tech sectors.

AgTechBiotechClimate TechFoodTechMedia & EntertainmentNorth Carolina, US

George H. Greene(Cofounder & CEO)

Co-investorsLeVert Ventures

Astranavastranav.comin

AstraNav develops positioning and navigation software that uses Earth's magnetic field to enable accurate location determination on devices without relying on satellites, Wi-Fi, or external infrastructure.

AI & Machine LearningDeep TechDefense TechIoTMobility & TransportationSaaS

Anton Toutov(CEO)inAlexandre "Sasha" Toutov(CTO & Inventor)in

Atalanatalantech.cominMay 2023

Atalan Tech develops clinician retention intelligence solutions for healthcare systems and organizations seeking to identify at-risk clinicians early, understand underlying causes of burnout and turnover, and implement targeted interventions to improve workforce sustainability.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechHR TechCalifornia, US

Tiffany ChaninSisi HuinTim Russo(Senior Healthcare Technology Executive)inSteven Strongwater(Director)Bob Saunders(Director)B. Bobby Bahram(Director)

Co-investorsBioAdvanceBroad Street AngelsEarly Light VenturesExcelerate Health VenturesOCA Ventures

Brainbox Solutionsbrainboxinc.cominOct 2023

BRAINBox Solutions develops a multi-modality diagnostic approach for mild traumatic brain injury (mTBI), combining blood biomarker panels with tablet-based neurocognitive testing to produce an objective injury score and a prognosis of post-injury symptoms.

AI & Machine LearningBiotechDigital HealthMedical DevicesHouston, US

Steve Wallace(Chief Operating Officer, Global Supply Chain Management)inDonna J. Edmonds(CEO)inJames V. Snider(Chief Technology Officer / Advisor)Tim Van Meter(Chief Scientific Officer)Richard Noel(Chief Product and Commercial Officer)inRobert Sledd(Director)

Co-investorsAmbit Health VenturesBioventures InvestorsGenoa VenturesGENERAL INCEPTION

Earth Opticsearthoptics.comin𝕏

EarthOptics measures soil health for farmers and landowners using field sensors and lab analysis to assess soil's physical, chemical, and biological properties.

AgTechAI & Machine LearningClimate TechData & InfrastructureDeep TechArlington, US

Lars Dyrud(CEO)inTodd Martin(Executive Officer)inStephanie Landa(Executive Officer)inHunt Bowers(Executive Officer)inAdam Gerson(Executive Officer)inJohn Dombrosky(Executive Officer, Director)

Co-investorsArgonautic VenturesCerity Partners VenturesCIBUS ENTERPRISE FUND II LPDoon CapitaliSelect FundMiddleland Capital+8 more

Empo Healthempohealth.comin

Empo Health develops in-home health monitoring devices for diabetic patients and healthcare providers to improve care outcomes.

Digital HealthHealthtechMedical DevicesSan Francisco, US

Eric Dahlseng(Founder)inAnuj Khandelwal(Founder)in

Co-investorsStartXStory VenturesUbiquity VenturesUlu VenturesGaingelsSeaX Ventures

KlariVisklarivis.comin

KlariVis provides data intelligence and analytics dashboards designed for community banks and financial institutions.

Data & InfrastructureEnterprise SoftwareFintechSaaSRichmond, US

Kim Snyder(Founder and CEO)in

Co-investorsBlueprint Equity

Middleland Capitalmiddlelandcapital.comApr 2023

Middleland Capital is a thematic venture capital fund that invests in foodtech and agtech companies focused on food and health.

AgTechFoodTech

Co-investorsRC Capital

PlanetiQplanetiq.comin𝕏

PlanetiQ provides satellite-based GNSS radio occultation data for weather forecasting, climate monitoring, and space weather prediction.

Climate TechData & InfrastructureDefense TechEnergySpace Tech

Chris McCormick(Founder, President and Chairman)inIra Scharf(Chief Executive Officer)inDr. Kursinski(Chief Scientist)

Co-investorsAccess Venture PartnersAV8 VenturesHemisphere Ventures LLCMoonshots CapitalNew Science VenturesService Provider Capital+4 more

Sedarosedaro.comin

Sedaro builds digital engineering and simulation infrastructure for national security missions, enabling complex systems to be designed, predicted, and decided upon with confidence through rigorous simulation.

AI & Machine LearningCloud ComputingDeep TechDefense TechEnterprise SoftwareSaaSSpace Tech

Robbie(Head of Product and Business Strategy)Bas(Head of Platform Development)Daniel(Head of Operations and Financial Strategy)

Co-investorsEarly Light VenturesSpice Capital

Slate Bioslatebio.cominDec 2020

Slate Bio develops regulatory T cell (Treg) therapies for treating autoimmune diseases.

BiotechDigital HealthMedical DevicesCharlottesville, US

Robert Creeden(Director)Kurt Woerpel(Executive Officer)Andrew J Krouse(Executive Officer, Director)

BoardKyparissia Sirinakis(Director)in

Co-investorsEpidarex Capital

Swarmswarm.engineeringin

SWARM is a decision intelligence platform that helps agrifood and manufacturing organizations solve operational challenges by defining problems clearly before deploying agentic AI and optimization algorithms.

Advanced ManufacturingAgTechAI & Machine LearningData & InfrastructureEnterprise Software

Co-investorsS2G InvestmentsHarvard Business Angels of ChicagoMiddleland CapitalAlumni VenturesChampion Hill VenturesCoatue Management+12 more

TearSolutionstearsolutions.comin

TearSolutions develops Lacripep, a topical peptide therapy derived from the Lacritin protein for the treatment of dry eye disease, including cases associated with primary Sjögren's Syndrome.

BiotechDigital HealthMedical DevicesCharlottesville, US

Gordon Laurie(Co-founder & Chief Scientific Officer)inMark B. Logan(Co-founder & Director)inRobert J Dempsey(Executive Officer, Director)inAnil Asrani(Executive Officer, Director)inThomas Gadek(Executive Officer, Director)Sanjay Asrani(President & CEO)

Co-investorsLaunchCapital

Tinycargotinycargo.comin

The Tiny Cargo Co. isolates milk-derived exosomes from cow's milk at industrial scale and loads them with therapeutic cargoes such as peptides, RNAs, and biologics for oral drug delivery.

BiotechDeep TechMedical DevicesRoanoke, US

Robert Gourdie(Founder and President)

Veracityvsveracityvs.comin

Veracity provides a centralized platform for educational institutions to manage their edtech application portfolios, enabling collaboration among technology, instructional, and business office leaders with visibility into software investments and stakeholder communication capabilities.

EdTechGovTechSaaS

Virginia Techvt.eduin𝕏

Virginia Tech is a public research university offering 110+ undergraduate majors and 120+ master's and doctoral degree programs across diverse fields.

EdTechBlacksburg, US

Tim Sandsin

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Carilion ClinicScout Space

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has VTC Ventures made?
VTC Ventures has 18 tracked investments, including 1 dated in the last 24 months.
What stage does VTC Ventures invest at?
VTC Ventures invests at the Pre-Seed, Seed, Series A stages.
What is VTC Ventures's typical check size?
VTC Ventures typically writes checks of $200K – $1M.
What sectors does VTC Ventures focus on?
VTC Ventures focuses on AgTech, AI & Machine Learning, Biotech, Consumer, Cybersecurity, Deep Tech, Defense Tech, Digital Health, Enterprise Software, FoodTech, Healthtech, Medical Devices, New Materials, Robotics, SaaS, Sector Agnostic.
Where is VTC Ventures located?
VTC Ventures is headquartered in Roanoke, US.
Does VTC Ventures lead rounds?
Yes, VTC Ventures leads investment rounds.
Who does VTC Ventures co-invest with?
VTC Ventures most often shares deals with Early Light Ventures, Epidarex Capital, Gaingels, among 35 tracked co-investors.

Images

VTC Ventures photo

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