Jonathan Leff
InvestorInvestor at Sofinnova Ventures
Menlo Park, California
Writes $100K β $5M checks Β· typically $1.5M
About
Jonathan Leff is a physician with over 25 years of clinical development experience in the biotechnology and pharmaceutical industry, advising companies on drug development from target identification through market approval. Before joining Sofinnova in 2020, he was SVP and Chief Medical Officer of Ascendis Pharma, EVP of Research and Development at InterMune (where he led development and US approval of Esbriet for idiopathic pulmonary fibrosis), and held CMO roles at KaloBios Pharmaceuticals and Halozyme Therapeutics, plus positions at Roche, Amgen, and Merck. He holds a B.A. in Chemistry and an M.D. from the University of Pennsylvania, and completed training in Internal Medicine and Pulmonary and Critical Care Medicine at the University of Colorado, Denver.
Invests in
Biotech
Experience
- Axonis TherapeuticsBoard Membercurrent2024 β presentBoston, Massachusetts, United States
- Sofinnova InvestmentsExecutive Partnercurrent2020 β presentMenlo Park
- Avalyn PharmaBoard Member2017 β 2026Greater Boston Area
- NorthSea TherapeuticsBoard Member2022 β 2026The Netherlands
- Aerovate TherapeuticsBoard Member2020 β 2021
- Ascendis Pharma A/SSenior Vice President and Chief Medical Officer2016 β 2019Palo Alto, CA
- InterMuneExecutive Vice President, Research and Development2012 β 2015Brisbane, CA
- KaloBios IncChief Medical Officer2011 β 2012San Francisco Bay Area
- Halozyme Therapeutics, Inc.Vice President and Chief Medical Officer2009 β 2010
- RocheVice President, Global Head Inflammation Clinical Development2007 β 2009
- RocheVice President2007 β 2009Palo Alto, California
- AmgenVice President - North America Medical Affairs2002 β 2007
- MerckSenior Director1994 β 2002
- University of Colorado Anschutz Medical CampusAssistant Professor1990 β 1994Denver, Colorado
Education
- University of Colorado AnschutzPulmonary/Critical Care Fellowship1987 β 1990
- University of Colorado AnschutzInternal Medicine Internship/Residency1984 β 1987
- University of Pennsylvania School of MedicineM.D., Medicine1980 β 1984
- University of PennsylvaniaB.A., Chemistry1975 β 1979
Skills & more
+12 more
DermatologyDrug DiscoveryInfectious DiseasesRegulatory AffairsCancerMedicineLifesciencesInternal MedicinePharmaceutical IndustryStrategyAnalysisLeadership- Diplomat, Critical Care Medicine β American Board of Internal Medicine
- Diplomat, American Board of Internal Medicine, Pulmonary Disease β American Board of Internal Medicine
- Diplomat, American Board of Internal Medicine β American Board of Internal Medicine
- License to Practice Medicine β State of California
From Jonathan's professional profile.
Same school
Also attended University of Colorado Anschutz3
Also attended University of Pennsylvania School of Medicine23
+ 17 more
Also attended University of Pennsylvania607
+ 601 more
Shared employers
Also worked at Axonis Therapeutics2
Also worked at InterMune1
Also worked at Roche75
+ 69 more
Also worked at Amgen53
+ 47 more
Deals Β· 3
Genoa PharmaceuticalsBoard seat
via Sofinnova Ventures Β· filed Oct 2023 Β· $189.2M raise
Adaptive Phage TherapeuticsBoard seat
via Sofinnova Ventures Β· filed Jun 2023 Β· $30M raise
Aerovate Therapeutics, Inc.Board seat
via Sofinnova Ventures Β· filed Aug 2020 Β· $75.8M raise
Attribution from SEC filings, press coverage, and firm rosters.




































