Plum Alley Investments
Venture capitalNew York · Pre-Seed–Series A · 15 people tracked
Also known as PLUM ALLEY MANAGEMENT LLC
Investment thesis
Plum Alley positions venture investing as a historically significant source of wealth creation and aims to broaden access to well-vetted opportunities and competitive allocations beyond the traditionally small pool of established investors. The firm emphasizes the current technological moment, driven by the convergence of increasing computational ability, new hardware innovation, and machine intelligence, as an extraordinary time to participate as a venture investor. It offers investors of all types a foothold in emerging deep technology areas expected to shape the future.
Source: firm website, verified Aug 25, 2026.
Team · 15 people
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What they invest in
from 26 of 29 portfolio companiesAI & Machine Learning ×14Biotech ×12Medical Devices ×12Healthtech ×11Cleantech ×5IoT ×5Digital Health ×4Climate Tech ×3
HQs:United States×22Sweden×1
Who they back
founder profiles across 24 portfolio companiesFounding team size:solo founder×92 founders×43 founders×74+ founders×4
Where their founders studiedfrom 17 founders with education data
Massachusetts Institute of Technology ×3
Where their founders worked beforefrom 20 founders with career history
Georgia Institute of Technology ×2Stanford University ×2
Accelerator rootsportfolio companies that came through a program
Investments · 29 tracked
founders shown can be your intro pathBy year:2024 · 22021 · 12015 · 14 dated
Co-investorsACVC Partnersblue 9 capitalBosch VenturesRethink ImpactRobert Bosch Venture CapitalGingerbread Capital
AiFi uses AI and computer vision to make physical spaces searchable, observable, and understandable, providing real-time insights for facility and space operators without manual audits.
AI & Machine LearningEnterprise SoftwareIoTRetail Tech
Steve Gu(Founder & CEO)Ying Zheng(Founder)
Co-investorsAmino CapitalCervinCommunitas Capital PartnersDuke Capital PartnersEvolution VenturesGS Futures+5 more
Co-investorsKapor CapitalFearless FundGingerbread Capital
ARIX combines robotics and data analytics to inspect and manage critical industrial assets.
AI & Machine LearningDeep TechEnergyIoTRoboticsJackson, US
Dianna Liu(President and CEO)in
Co-investorsAlleyCorpContour Venture PartnersDorm RoomEnergy Transition VenturesInnovation Catalystkineo finance+4 more
AVTTX is a clinical-stage company developing gene therapy treatments for retinal and ophthalmologic diseases.
BiotechDigital HealthHealthtechMedical Devices
George Montgomery(Executive Chairman)
Co-investorsEcoR1 CapitalEvolution VC PartnersHelios CapitalSocii CapitalTribe Capital Firstlook
Biobot pioneers wastewater epidemiology, monitoring pathogens and substances in sewage to provide real-time public health surveillance at the community level.
BiotechData & InfrastructureGovTechHealthtechBoston, US
Newsha Ghaeli(Cofounder & President)inMariana Matus(Founder)inMariana Guadalupe Matus Garcia(Executive Officer, Director)
BoardVivek Pattipati(Director)inAndrew Perlman(Director)in
Co-investorsAmerican Family Insurance Institute for Corporate and Social ImpactBlindspot Ventures Management CoDCVC (Data Collective)Dorm RoomHomebrewPathbreaker Ventures+5 more
BioEclipse Therapeutics is a clinical-stage oncology company developing immuno-oncology therapeutics using a proprietary platform that targets the tumor microenvironment through engineered immune cell therapies.
BiotechDigital HealthHealthtechMedical DevicesSouth San Francisco, US
Pamela Reilly Contag(Executive Officer, Director)Catherine Sohn(Director)Gregory Schiffman(Director)Mark Frohlich(Director)Stephen Thau(Executive Officer)Elona Baum(Director)
Co-investorsFoothill Ventures
Cordex Systems develops SmartCuff, a medical device that repurposes blood pressure cuff technology as a linear sensor to detect early warning signs of heart disease.
AI & Machine LearningBiotechHealthtechMedical DevicesAnnapolis, US
Kathy Elizabeth Magliato(Executive Officer, Director, Promoter)Albert Fleury IIIinMichael Whittin
BoardDennis SchmulandinGeorge Abein
Co-investorsGingerbread Capital
Diligent Robotics develops AI-powered robot assistants for healthcare settings, focusing on mobile manipulation and social intelligence to help hospital staff with routine non-patient-facing tasks.
AI & Machine LearningHealthtechMedical DevicesRoboticsAustin, US
Andrea Thomaz(Founder & CEO)Andrea L. Thomaz(Founder)inVivian Chu(Founder)inQuaeed Motiwala(Director)Lance VandenBrook(Director)Richard Boyle(Director)
Co-investorsATPCanaan PartnersCorrelation VenturesDnx VenturesGrit VenturesNext Coast Ventures+6 more
Einride develops autonomous electric vehicles and fleet management solutions for decarbonization, serving large enterprises seeking to reduce emissions at scale.
AI & Machine LearningCleantechClimate TechLogistics & Supply ChainMobility & TransportationStockholm, SE
Robert Falck(Founder and Executive Chairman)inLinnéa Kornehed Falck(Co-Founder)inFilip Lilja(Co-Founder)inRoozbeh Charli(CEO)Henrik Green(CTO)
Co-investorsMaersk GrowthNordicNinjaNordicNinjaVCNorthzoneEQT VenturesPlug and Play Ventures+1 more
EpiBone engineers bone tissue from stem cells for regenerative medicine and clinical reconstruction, serving patients requiring bone grafts or craniofacial repair.
BiotechHealthtechMedical DevicesNew York, US
Nina Tandon(Co-Founder, CEO)Sarindr Bhumiratana(Co-Founder)Gordana Vunjak-Novakovic(Director)Elma Hawkins(Director)
BoardRobert Langer(Director)David Zhu(Director)
Co-investorsBeresford VenturesEMV CapitalHackensack Meridian Health Bear's DenKendall Capital PartnersTachyon VenturesTech Council Ventures
Evrnu develops technology to transform textile waste into recyclable fibers for apparel manufacturing, creating sustainable alternatives to conventional textiles without compromising quality or performance.
Circular EconomyCleantechClimate TechNew MaterialsSeattle, US
Christopher Stanev(Executive Officer, Director)Stacy Flynn(Executive Officer, Director)Christopher Stenev(Executive Officer, Director, Promoter)
BoardCorey Vernon(Director)inKyle Adkins(Director)Julie Guggemos(Director)
Co-investorsMagic HourRadicle Impact
One Health operates a clinical trial platform using canine cancer data to accelerate and de-risk human oncology drug development.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesSan Francisco, US
Christina Lopes(Co-Founder & CEO)inBen Lewis(Co-founder)Benjamin Lewis(Co-Founder)inchristina lopes(Founder)in
Co-investorsAndreessen HorowitzaVentureCivilization Ventures Management, LlcGlobal BrainMaC Venture CapitalMyAsiaVC+5 more
Gameto develops cell therapy and reproductive technologies to treat infertility and improve women's health outcomes.
BiotechFemTechHealthtechMedical DevicesAustin, US
Dina Turner(Co-founder & Chief Executive Officer)inMartin Varsavsky(Co-founder & Chairman)inDina Radenkovic(Executive Officer, Director)
BoardDusan Perovic(Director)inDylan Morris(Director)Maryanna Saenko(Director)in
Co-investorsBold Capital PartnersFuture VenturesIngeborg InvestmentsJazzya InvestmentsKorify CapitalLux Capital+11 more
Helaina uses precision fermentation to produce human proteins, including lactoferrin and other bioactive nutrients found in human milk, for consumer nutrition products serving athletes, new parents, and health-conscious consumers.
AI & Machine LearningBiotechFoodTechHealthtechNew York, US
Laura Katz(Founder & CEO)in
Co-investorsBarrel VenturesCosmic Venture PartnersIngeborg InvestmentsTrousdale VenturesPrimary Venture PartnersSpark Capital
humans& is a frontier AI lab focused on building human-centric AI systems that prioritize people and their relationships, emphasizing innovations in reinforcement learning, memory, and user understanding to create AI that strengthens organizations and communities.
AI & Machine LearningEnterprise SoftwareSaaSEl Segundo, US
Eric Zelikman(Co-founder)Noah Goodman(Founder)inAlaarif Nooruldeen(Executive Officer, Director)
BoardKristen Green(Director)Allen Mask(Director)Jonathan Ellman(Director)
Co-investorsGV (Google Ventures)S32SV AngelNVIDIAA.Capital VenturesChamaeleon+6 more
InnerPlant develops living sensor technology that enables farmers to detect plant stress in real-time, allowing targeted application of treatments to reduce chemical use and increase crop yields.
AgTechBiotechIoTCalifornia, US
RodinShely Aronov(Executive Officer, Director)Gary Schaefer(Chief Commercial Officer)in
Co-investorsBison VenturesCultiv8 Funds ManagementKokopelli CapitalMS&AD VenturesSystemiq CapitalTAU Ventures+3 more
Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.
AI & Machine LearningBiotechLongevityMedical DevicesRedwood City, US
Jeremy O'Connell, PhD(Chief Scientific Officer and Co-Founder)Hanadie Yousef, PhD(Executive Advisor and Co-Founder)Hanadie Yousef(Executive Officer, Director)Jeremy O'Connell(Director)Dr. Hanadie Yousef(Founder)in
BoardBen Hemani(Director)in
Co-investorsBascom VenturesBison VenturesCompoundHarmonix FundHorizons VenturesManta Ray Ventures+3 more
KETOS develops an automated water quality and monitoring platform combining hardware, connectivity, software, and services to test water safety and efficiency for cities and businesses.
AI & Machine LearningCleantechData & InfrastructureEnterprise SoftwareIoTMilpitas, US
Meena Sankaran(Executive Officer, Director)Veery Maxwell(Director)
BoardHeidi Patel(Director)inOllen Douglass(Director)
Co-investorsRethink ImpactBetter Ventures Central LlcMotley Fool VenturesThe Perkins FundAccenture Ventures
Kraus Hamdani Aerospace develops ultra-long-endurance autonomous aircraft and AI-enabled airborne systems that provide persistent connectivity, intelligence, and communications infrastructure for defense and national security missions.
AI & Machine LearningDefense TechHardwareIoTRoboticsReno, US
Fatema Hamdani(Co-Founder, CEO)Stefan Kraus(Co-Founder, CTO)
Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.
BiotechDeep TechMedical DevicesBrisbane, US
Jennifer Doudna(Founder)inTrevor Martin(Co-founder, Chief Executive Officer)inJanice Chen(Co-founder, Chief Scientific Officer & President, Research)inLucas Harrington(Co-founder)inAshley Tehranchi(Executive Officer, Director)
BoardUrshit Parikh(Director)
Co-investors8VCBerkeley FrontierCALIFORNIA INNOVATIONDecheng CapitalForesite CapitalMayfield Fund+9 more
Markable.ai is an all-in-one platform for affiliate creators to monetize content through Amazon, Target, and Walmart deeplinks, featuring automated tools for link management, content boosting, and performance optimization.
AI & Machine LearningCreator EconomyMarketing TechMadison, US
Joy Tang(Executive Officer, Director)inFiona Wang(Executive Officer, Director)
BoardSheng Fu(Director)
Co-investorsArbor VenturesFounderPartnersNOEMIS VenturesHeadline
Openwater develops an imaging platform using two optical modalities designed to diagnose and monitor diseases at the size and cost of a smartphone.
AI & Machine LearningDeep TechHealthtechMedical DevicesSan Francisco, US
Dr. Mary Lou Jepsen(Executive Chairman & Founder)in
Co-investorsAIR CapitalBold Capital PartnersCollaborative FundResolute VenturesUntapped Ventures
Openwater develops miniaturized medical devices that use light, sound, and electromagnetic manipulation to treat diseases including cancers, stroke, and mental illness, operating as a hardware and AI platform for physiological data collection and treatment.
AI & Machine LearningHardwareMedical Devices
Co-investorsExcel Venture ManagementLauder PartnersBold Capital PartnersKhosla VenturesStarlight Ventures
Phoenix Tailings develops clean technology for rare earth element refining in the United States.
Advanced ManufacturingCleantechClimate TechEnergyFintechNew MaterialsBoston, US
Nick Myers(CEO & Co-Founder)Thomas Villalón(CTO & Co-Founder)Anthony Balladon(Chief Commercial Officer & Co-Founder)Michelle Chao(Cofounder)Nicholas Myers(Founder)in
BoardNichola Eliovits(Director)in
Co-investorsBantam GroupBMW i VenturesCoalitionGeodesic CapitalMPowerOlive Tree Capital+9 more
Siren Biotechnology develops next-generation AAV (adeno-associated virus) platforms for gene therapy applications, including gene repair, gene transfer, and gene editing.
BiotechDigital HealthMedical DevicesSan Francisco, US
Dr. Nicole Paulk(CEO, Founder, and President)Nicole Paulk(Executive Officer, Director)Lauren Kelly(Founder)inSharon Tetlow(Director)Brad Allen(Director)
Co-investorsArtis VenturesAvilaCarnrite VenturesCivilization Ventures Management, LlcHAWKTAILNZVC+2 more
ThinkCERCA develops K-12 writing software and curriculum designed to teach critical thinking skills to students through structured literacy instruction.
EdTech
Eileen Murphy
Co-investorsEdovate CapitalGingerbread CapitalImpact Engine
Northampton, US
Brian Fitzgerald(Executive Officer, Director)inMeghan Fitzgerald(Director)
BoardIsabelle Hau(Director)
Co-investorsBlue CollectiveCity LightOutbound VenturesOwl VenturesVista Venture Partners500 Global+5 more
Vyv develops UV-free, chemical-free antimicrobial lighting technology using visible spectrum LEDs that continuously reduce microbial growth in occupied indoor spaces.
CleantechHardwareHealthtech
Colleen Costello(CEO)
Co-investorsAlerion VenturesTamiami AngelTech Square VenturesCiti Ventures
Portfolio news
latest coverage across their companies
Phoenix Tailings · techstars.com · Jul 17, 2026
Gameto · smartcompany.com.au · Jul 17, 2026
Juvena Therapeutics · newmarketpitch.com · Jul 13, 2026
FidoCure · aventure.vc · May 31, 2026
MARKABLE · lacrossetribune.com · May 18, 2026
Einride · finance.yahoo.com · Mar 1, 2026
humans& · techcrunch.com · Jan 20, 2026
Frequently asked questions
- How many investments has Plum Alley Investments made?
- Plum Alley Investments has 27 tracked investments.
- What stage does Plum Alley Investments invest at?
- Plum Alley Investments invests at the Pre-Seed, Seed, Series A stages.
- What is Plum Alley Investments's typical check size?
- Plum Alley Investments typically writes checks of $500K – $1.5M.
- What sectors does Plum Alley Investments focus on?
- Plum Alley Investments focuses on AI & Machine Learning, Biotech, Deep Tech, Enterprise Software, Hardware, Impact & Social Good, Medical Devices.
- Where is Plum Alley Investments located?
- Plum Alley Investments is headquartered in New York, US.
- Does Plum Alley Investments lead rounds?
- Plum Alley Investments typically participates in rounds rather than leading them.
- Who does Plum Alley Investments co-invest with?
- Plum Alley Investments most often shares deals with Bold Capital Partners, Civilization Ventures Management, Llc, Rethink Impact, among 142 tracked co-investors.
Co-investors · 20
Rethink Impact is a venture capital firm that backs leaders using technology to address major global challenges, focused on mission-driven companies aiming to benefit all communities.
Tachyon Ventures provides early-stage capital to entrepreneurs building companies in medicine, biotech and bioengineering, supported by a network of scientists at leading research institutions.
Khosla Ventures is a venture capital firm that invests in early-stage companies focused on technology, mobile, and clean energy sectors, including biotechnology applications. The firm provides capital and strategic support to entrepreneurs developing breakthrough technologies across multiple markets.
Spark Capital is a venture capital firm that partners with founders, known for early investments including leading Twitter's Series B in 2008.
Mayfield is a venture capital firm that invests in early-stage consumer and marketplace companies, backing founders from inception through IPO.
EQT Ventures is the venture capital arm within the EQT platform, backing early-stage European founders building what it calls Generation-Defining Companies.
Northzone is a technology-focused venture capital firm investing across AI and deep tech on both sides of the Atlantic, backing companies from early stage through growth.
Robert Bosch Venture Capital GmbH (Bosch Ventures) is the corporate venture capital arm of Bosch, headquartered in Stuttgart, Germany, with additional offices in Frankfurt, Sunnyvale, Boston, Tel Aviv, and Shanghai.
Great Oaks Venture Capital is a New York-based early-stage investor that partners with founders at the earliest stages of company building across the United States.
Hustle Fund is an early-stage venture capital firm that invests quickly in startups, offering capital along with educational programs and mentorship. It also runs an angel investing community that lets members invest alongside the fund.
Pareto Holdings is an early-stage investment and company-building firm headquartered in the United States that operates globally. It has never raised outside capital and is self-funded by design.
▶8 more co-investors
AntlerNext Play VenturesNorrsken VCTriatomic CapitalClearvision VenturesConteur Capital PartnersS2G InvestmentsTectonic Capital
Firms observed investing alongside Plum Alley Investments, from public investor directories. Shared companies are the overlap with Plum Alley Investments's recorded portfolio.
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