Plum Alley Investments
New York · Series A · 8 people tracked
Investment thesis
Plum Alley Ventures focuses on frontier technology and medical breakthroughs at Series A stage, prioritizing B2B startups with patented IP and technical applications designed to impact at least one billion people. The firm emphasizes backing gender-diverse founding teams developing innovations intended to create large-scale humanitarian benefit.
Source: firm website, verified Jul 20, 2026.
Team · 8 people
from the firm's websiteWhat they invest in
from 25 of 28 portfolio companiesAI & Machine Learning ×13Biotech ×12Healthtech ×11Medical Devices ×11Cleantech ×5IoT ×5Digital Health ×4Climate Tech ×3
HQs:United States×13Sweden×1
Investments · 28 tracked
founders shown can be your intro pathARIX combines robotics and data analytics to inspect and manage critical industrial assets. The company serves customers across industries seeking to improve safety and reduce maintenance costs through automated inspection solutions.
AI & Machine LearningDeep TechEnergyIoTRobotics
AVTTX is a clinical-stage company developing gene therapy treatments for retinal and ophthalmologic diseases. The company leverages adeno-associated virus (AAV) technology to address unmet medical needs in vision care.
BiotechDigital HealthHealthtechMedical Devices
George Montgomery(Executive Chairman)<UNKNOWN>(Chief Executive Officer and Founder)
Biobot pioneers wastewater epidemiology, monitoring pathogens and substances in sewage to provide real-time public health surveillance at the community level. The company serves public health agencies, vaccine manufacturers, and hospital systems globally.
BiotechData & InfrastructureGovTechHealthtechBoston, US
Newsha Ghaeli(President and Cofounder)inMariana Matus(CEO and Cofounder)in
BioEclipse Therapeutics is a clinical-stage oncology company developing immuno-oncology therapeutics using a proprietary platform that targets the tumor microenvironment through engineered immune cell therapies. The company's approach combines multiple mechanisms of action to eradicate cancer cells and generate durable immune responses against relapse and recurrence.
BiotechDigital HealthHealthtechMedical Devices
Cordex Systems develops SmartCuff, a medical device that repurposes blood pressure cuff technology as a linear sensor to detect early warning signs of heart disease. The device is designed for healthcare professionals and patients at risk of cardiovascular disease.
AI & Machine LearningBiotechHealthtechMedical Devices
Kathy MagliatoAlbert Fleury IIIMichael WhittGeorge Abe
Einride develops autonomous electric vehicles and fleet management solutions for decarbonization, serving large enterprises seeking to reduce emissions at scale.
AI & Machine LearningCleantechClimate TechLogistics & Supply ChainMobility & TransportationStockholm, SE
Roozbeh Charli(CEO)Henrik Green(CTO)
EpiBone engineers bone tissue from stem cells for regenerative medicine and clinical reconstruction, serving patients requiring bone grafts or craniofacial repair. The company translates tissue engineering research into therapeutic products for orthopedic and surgical applications.
BiotechHealthtechMedical Devices<UNKNOWN>, US
Nina Tandon(Co-Founder, CEO)Sarindr Bhumiratana(Co-Founder)
Evrnu develops technology to transform textile waste into recyclable fibers for apparel manufacturing, creating sustainable alternatives to conventional textiles without compromising quality or performance.
Circular EconomyCleantechClimate TechNew Materials
One Health operates a clinical trial platform using canine cancer data to accelerate and de-risk human oncology drug development. The company leverages a dataset of 2 billion datapoints from dogs with naturally occurring cancer to serve as a comparative model for pharmaceutical R&D, helping drug developers validate efficacy and identify biomarkers before human trials.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesSan Francisco, US
Christina K. Lopes(CEO)christina lopes(Founder)inBen Lewis(Co-founder)Christina Lopes(Co-founder)
Helaina uses precision fermentation to produce human proteins, including lactoferrin and other bioactive nutrients found in human milk, for consumer nutrition products serving athletes, new parents, and health-conscious consumers.
AI & Machine LearningBiotechFoodTechHealthtech
<UNKNOWN>Laura Katz(Founder & CEO)
humans& is a frontier AI lab focused on building human-centric AI systems that prioritize people and their relationships, emphasizing innovations in reinforcement learning, memory, and user understanding to create AI that strengthens organizations and communities.
AI & Machine LearningEnterprise SoftwareSaaS
Eric Zelikman(Co-founder)
Gameto develops cell therapy and reproductive technologies to treat infertility and improve women's health outcomes. The company uses stem cell biology and in vitro maturation techniques to create innovative solutions for patients seeking family-building options.
BiotechFemTechHealthtechMedical DevicesAustin, US
Dina Turner(Co-founder & Chief Executive Officer)Martin Varsavsky(Co-founder & Chairman)
InnerPlant develops living sensor technology that enables farmers to detect plant stress in real-time, allowing targeted application of treatments to reduce chemical use and increase crop yields. The company serves agricultural producers seeking data-driven solutions for sustainable crop management.
AgTechBiotechIoTCalifornia, US
Gary Schaefer(Chief Commercial Officer)ShelyRod
Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.
AI & Machine LearningBiotechLongevityMedical Devices
Jeremy O'Connell, PhD(Chief Scientific Officer and Co-Founder)Hanadie Yousef, PhD(Executive Advisor and Co-Founder)
KETOS develops an automated water quality and monitoring platform combining hardware, connectivity, software, and services to test water safety and efficiency for cities and businesses. The company replaces manual, slow testing processes with real-time intelligence for leak detection, usage monitoring, and composition analysis.
AI & Machine LearningCleantechData & InfrastructureEnterprise SoftwareIoT<UNKNOWN>, US
Kraus Hamdani Aerospace develops ultra-long-endurance autonomous aircraft and AI-enabled airborne systems that provide persistent connectivity, intelligence, and communications infrastructure for defense and national security missions. The company serves military and government teams operating in complex, remote, and contested environments where satellite and terrestrial coverage is unreliable.
AI & Machine LearningDefense TechHardwareIoTRoboticsReno, US
Fatema Hamdani(Co-Founder, CEO)Stefan Kraus(Co-Founder, CTO)
Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.
BiotechDeep TechMedical DevicesBrisbane, US
Jennifer Doudna(Founder)Trevor Martin(Co-founder, Chief Executive Officer)Janice Chen(Co-founder, Chief Scientific Officer & President, Research)Lucas Harrington(Co-founder)
A CRISPR technology company developing next-generation systems for in vivo gene therapy with therapeutic partnerships with Bayer and Vertex.
Markable.ai is an all-in-one platform for affiliate creators to monetize content through Amazon, Target, and Walmart deeplinks, featuring automated tools for link management, content boosting, and performance optimization. The platform serves social media creators seeking to increase affiliate commission income through AI-powered content amplification and unified workflow management.
AI & Machine LearningCreator EconomyMarketing Tech
Diligent Robotics develops AI-powered robot assistants for healthcare settings, focusing on mobile manipulation and social intelligence to help hospital staff with routine non-patient-facing tasks. The company's flagship product, Moxi, enables clinical staff to dedicate more time to direct patient care.
AI & Machine LearningHealthtechMedical DevicesRoboticsAustin, US
<UNKNOWN>
Openwater develops an imaging platform using two optical modalities designed to diagnose and monitor diseases at the size and cost of a smartphone. The platform combines hardware, software, and open-source designs for use in clinical settings at hospitals, research institutions, and government programs worldwide, with trials spanning cancer, neurological disease, mental health, and metabolic conditions.
AI & Machine LearningDeep TechHealthtechMedical DevicesSan Francisco, US
Dr. Mary Lou Jepsen(Executive Chairman & Founder)
Phoenix Tailings develops clean technology for rare earth element refining in the United States. The company operates across the full value chain, from mining and recycling to separation and magnet production.
Advanced ManufacturingCleantechClimate TechFintechNew MaterialsBoston, US
Nick Myers(CEO & Co-Founder)Thomas Villalón(CTO & Co-Founder)Anthony Balladon(Chief Commercial Officer & Co-Founder)
Siren Biotechnology develops next-generation AAV (adeno-associated virus) platforms for gene therapy applications, including gene repair, gene transfer, and gene editing. The company focuses on advancing treatments for a wide range of rare diseases through engineered viral vectors and directed evolution approaches.
BiotechDigital HealthMedical Devices
Dr. Nicole Paulk(CEO, Founder, and President)
ThinkCERCA develops K-12 writing software and curriculum designed to teach critical thinking skills to students through structured literacy instruction. The company serves schools and districts with educational technology tools and professional development resources.
EdTech
Eileen Murphy
AiFi uses AI and computer vision to make physical spaces searchable, observable, and understandable, providing real-time insights for facility and space operators without manual audits.
AI & Machine LearningEnterprise SoftwareIoTRetail Tech<UNKNOWN>, US
Vyv develops UV-free, chemical-free antimicrobial lighting technology using visible spectrum LEDs that continuously reduce microbial growth in occupied indoor spaces. The company serves healthcare, travel, food and beverage, agriculture, and fitness industries with integrated solutions designed for always-on protection in buildings and environments.
CleantechHardwareHealthtech
Colleen Costello(CEO)
Frequently asked questions
- What stage does Plum Alley Investments invest at?
- Plum Alley Investments invests at the Series A stage.
- What sectors does Plum Alley Investments focus on?
- Plum Alley Investments focuses on Deep Tech, Medical Devices.
- Where is Plum Alley Investments located?
- Plum Alley Investments is headquartered in New York, US.
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