Plum Alley Investments
Venture capitalNew York · Pre-Seed–Series A · 15 people tracked
Also known as PLUM ALLEY MANAGEMENT LLC
Investment thesis
Plum Alley positions venture investing as a historically significant source of wealth creation and aims to broaden access to well-vetted opportunities and competitive allocations beyond the traditionally small pool of established investors. The firm emphasizes the current technological moment, driven by the convergence of increasing computational ability, new hardware innovation, and machine intelligence, as an extraordinary time to participate as a venture investor. It offers investors of all types a foothold in emerging deep technology areas expected to shape the future.
Source: firm website, verified Aug 3, 2026.
Team · 15 people
from the firm's website & public directories
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What they invest in
from 26 of 28 portfolio companiesAI & Machine Learning ×14Biotech ×12Medical Devices ×12Healthtech ×11Cleantech ×5IoT ×5Digital Health ×4Climate Tech ×3
HQs:United States×19Sweden×1
Investments · 28 tracked
founders shown can be your intro pathARIX combines robotics and data analytics to inspect and manage critical industrial assets.
AI & Machine LearningDeep TechEnergyIoTRoboticsJackson, US
Dianna Liu(President and CEO)
AVTTX is a clinical-stage company developing gene therapy treatments for retinal and ophthalmologic diseases.
BiotechDigital HealthHealthtechMedical Devices
George Montgomery(Executive Chairman)
Biobot pioneers wastewater epidemiology, monitoring pathogens and substances in sewage to provide real-time public health surveillance at the community level.
BiotechData & InfrastructureGovTechHealthtechBoston, US
Newsha Ghaeli(Cofounder & President)inMariana Matus(Founder)inVivek Pattipati(Director)Andrew Perlman(Director)Mariana Guadalupe Matus Garcia(Executive Officer, Director)
BioEclipse Therapeutics is a clinical-stage oncology company developing immuno-oncology therapeutics using a proprietary platform that targets the tumor microenvironment through engineered immune cell therapies.
BiotechDigital HealthHealthtechMedical Devices
Catherine Sohn(Director)Gregory Schiffman(Director)Biao He(Director)Mark Frohlich(Director)Stephen Thau(Executive Officer)Elona Baum(Director)
Cordex Systems develops SmartCuff, a medical device that repurposes blood pressure cuff technology as a linear sensor to detect early warning signs of heart disease.
AI & Machine LearningBiotechHealthtechMedical Devices
Albert Fleury IIIinMichael WhittinKathy Elizabeth Magliato(Executive Officer, Director, Promoter)
Diligent Robotics develops AI-powered robot assistants for healthcare settings, focusing on mobile manipulation and social intelligence to help hospital staff with routine non-patient-facing tasks.
AI & Machine LearningHealthtechMedical DevicesRoboticsAustin, US
Andrea Thomaz(Founder & CEO)
Einride develops autonomous electric vehicles and fleet management solutions for decarbonization, serving large enterprises seeking to reduce emissions at scale.
AI & Machine LearningCleantechClimate TechLogistics & Supply ChainMobility & TransportationStockholm, SE
Roozbeh Charli(CEO)Henrik Green(CTO)
EpiBone engineers bone tissue from stem cells for regenerative medicine and clinical reconstruction, serving patients requiring bone grafts or craniofacial repair.
BiotechHealthtechMedical Devices<UNKNOWN>, US
Nina Tandon(Co-Founder, CEO)Sarindr Bhumiratana(Co-Founder)Robert Langer(Director)Gordana Vunjak-Novakovic(Director)David Zhu(Director)Elma Hawkins(Director)
Evrnu develops technology to transform textile waste into recyclable fibers for apparel manufacturing, creating sustainable alternatives to conventional textiles without compromising quality or performance.
Circular EconomyCleantechClimate TechNew MaterialsSeattle, US
Christopher Stanev(Executive Officer, Director)Stacy Flynn(Executive Officer, Director)Christopher Stenev(Executive Officer, Director, Promoter)
BoardCorey Vernon(Director)Kyle Adkins(Director)Julie Guggemos(Director)
Gameto develops cell therapy and reproductive technologies to treat infertility and improve women's health outcomes.
BiotechFemTechHealthtechMedical DevicesAustin, US
Dina Turner(Co-founder & Chief Executive Officer)inMartin Varsavsky(Co-founder & Chairman)inDusan Perovic(Director)Dina Radenkovic(Executive Officer, Director)Dylan Morris(Director)Maryanna Saenko(Director)
Helaina uses precision fermentation to produce human proteins, including lactoferrin and other bioactive nutrients found in human milk, for consumer nutrition products serving athletes, new parents, and health-conscious consumers.
AI & Machine LearningBiotechFoodTechHealthtechNew York, US
Laura Katz(Founder & CEO)in
humans& is a frontier AI lab focused on building human-centric AI systems that prioritize people and their relationships, emphasizing innovations in reinforcement learning, memory, and user understanding to create AI that strengthens organizations and communities.
AI & Machine LearningEnterprise SoftwareSaaSEl Segundo, US
Eric Zelikman(Co-founder)Alaarif Nooruldeen(Executive Officer, Director)Kristen Green(Director)Allen Mask(Director)Jonathan Ellman(Director)Eduardo Vivas(Director)
InnerPlant develops living sensor technology that enables farmers to detect plant stress in real-time, allowing targeted application of treatments to reduce chemical use and increase crop yields.
AgTechBiotechIoTCalifornia, US
RodinGary Schaefer(Chief Commercial Officer)inShely Aronov(Executive Officer, Director)
Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.
AI & Machine LearningBiotechLongevityMedical DevicesRedwood City, US
Jeremy O'Connell, PhD(Chief Scientific Officer and Co-Founder)Hanadie Yousef, PhD(Executive Advisor and Co-Founder)Steven James(Director)inStephen Juelsgaard(Director)inHanadie Yousef(Executive Officer, Director)Laura Lande-Diner(Director)in
KETOS develops an automated water quality and monitoring platform combining hardware, connectivity, software, and services to test water safety and efficiency for cities and businesses.
AI & Machine LearningCleantechData & InfrastructureEnterprise SoftwareIoT<UNKNOWN>, US
Meena Sankaran(Executive Officer, Director)Heidi Patel(Director)Veery Maxwell(Director)Ollen Douglass(Director)
Kraus Hamdani Aerospace develops ultra-long-endurance autonomous aircraft and AI-enabled airborne systems that provide persistent connectivity, intelligence, and communications infrastructure for defense and national security missions.
AI & Machine LearningDefense TechHardwareIoTRoboticsReno, US
Fatema Hamdani(Co-Founder, CEO)Stefan Kraus(Co-Founder, CTO)
Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.
BiotechDeep TechMedical DevicesBrisbane, US
Jennifer Doudna(Founder)inTrevor Martin(Co-founder, Chief Executive Officer)Janice Chen(Co-founder, Chief Scientific Officer & President, Research)Lucas Harrington(Co-founder)inUrshit Parikh(Director)Ashley Tehranchi(Executive Officer, Director)
Markable.ai is an all-in-one platform for affiliate creators to monetize content through Amazon, Target, and Walmart deeplinks, featuring automated tools for link management, content boosting, and performance optimization.
AI & Machine LearningCreator EconomyMarketing TechMadison, US
Sheng Fu(Director)Fiona Wang(Executive Officer, Director)Joy Tang(Executive Officer, Director)
Openwater develops an imaging platform using two optical modalities designed to diagnose and monitor diseases at the size and cost of a smartphone.
AI & Machine LearningDeep TechHealthtechMedical DevicesSan Francisco, US
Dr. Mary Lou Jepsen(Executive Chairman & Founder)in
Openwater develops miniaturized medical devices that use light, sound, and electromagnetic manipulation to treat diseases including cancers, stroke, and mental illness, operating as a hardware and AI platform for physiological data collection and treatment.
AI & Machine LearningHardwareMedical Devices
Phoenix Tailings develops clean technology for rare earth element refining in the United States.
Advanced ManufacturingCleantechClimate TechEnergyFintechNew MaterialsBoston, US
Nick Myers(CEO & Co-Founder)Thomas Villalón(CTO & Co-Founder)Anthony Balladon(Chief Commercial Officer & Co-Founder)Nichola Eliovits(Director)Steve Bolze(Director)Yong Hyun Kim(Director)
Siren Biotechnology develops next-generation AAV (adeno-associated virus) platforms for gene therapy applications, including gene repair, gene transfer, and gene editing.
BiotechDigital HealthMedical DevicesSan Francisco, US
Dr. Nicole Paulk(CEO, Founder, and President)Sharon Tetlow(Director)Brad Allen(Director)Nicole Paulk(Executive Officer, Director)
ThinkCERCA develops K-12 writing software and curriculum designed to teach critical thinking skills to students through structured literacy instruction.
EdTech
Eileen Murphy
Frequently asked questions
- What stage does Plum Alley Investments invest at?
- Plum Alley Investments invests at the Pre-Seed, Seed, Series A stages.
- What is Plum Alley Investments's typical check size?
- Plum Alley Investments typically writes checks of $500K – $1.5M.
- What sectors does Plum Alley Investments focus on?
- Plum Alley Investments focuses on AI & Machine Learning, Biotech, Deep Tech, Enterprise Software, Hardware, Impact & Social Good, Medical Devices.
- Where is Plum Alley Investments located?
- Plum Alley Investments is headquartered in New York, US.
- Does Plum Alley Investments lead rounds?
- Plum Alley Investments typically participates in rounds rather than leading them.
Co-investors · 20
Rethink Impact is a venture capital firm that backs leaders using technology to address major global challenges, focused on mission-driven companies aiming to benefit all communities.
Tachyon Ventures provides early-stage capital to entrepreneurs building companies in medicine, biotech and bioengineering, supported by a network of scientists at leading research institutions.
Khosla Ventures is a venture capital firm known for backing bold, contrarian bets in world-class teams that can reshape entire industries.
Spark Capital is a venture capital firm that backs founders across technology and consumer companies; it notably led Twitter's Series B in 2008.
Mayfield Fund is a venture capital firm publishing perspectives on artificial intelligence, focusing on what it calls the Collaborative Intelligence era where humans and AI work together.
Northzone is a multi-stage venture capital firm investing from seed to growth.
Robert Bosch Venture Capital GmbH (Bosch Ventures) is the corporate venture capital arm of Bosch, headquartered in Stuttgart, Germany, with additional offices in Frankfurt, Sunnyvale, Boston, Tel Aviv, and Shanghai.
Great Oaks Venture Capital is a New York-based early-stage investor that partners with founders at the earliest stages of company building across the United States.
EQT Ventures is the early-stage venture arm of EQT, backing founders building what it calls Generation-Defining Companies, primarily across Europe. It acts as a lead investor, operational advisor, and high-conviction capital provider.
Hustle Fund is an early-stage venture capital firm that invests quickly in startups, offering capital along with educational programs and mentorship. It also runs an angel investing community that lets members invest alongside the fund.
Pareto Holdings is an early-stage investment and company-building firm headquartered in the United States that operates globally. It has never raised outside capital and is self-funded by design.
▶8 more co-investors
AntlerNext Play VenturesNorrsken VCTriatomic CapitalClearvision VenturesConteur Capital PartnersS2G InvestmentsTectonic Capital
Firms observed investing alongside Plum Alley Investments, from public investor directories. Shared companies are the overlap with Plum Alley Investments's recorded portfolio.
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