Plum Alley Investments
Venture capitalNew York · Seed–Series A · 15 people tracked
Also known as PLUM ALLEY MANAGEMENT LLC
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Investment thesis
Plum Alley positions venture investing as a historically significant source of wealth creation and aims to broaden access to well-vetted opportunities and competitive allocations beyond the traditionally small pool of established investors. The firm emphasizes the current technological moment, driven by the convergence of increasing computational ability, new hardware innovation, and machine intelligence, as an extraordinary time to participate as a venture investor. It offers investors of all types a foothold in emerging deep technology areas expected to shape the future.
Source: firm website, verified Sep 29, 2026.
Team · 15 people
from the firm's website & public directoriesWhat they invest in
from 29 of 31 portfolio companiesAI & Machine Learning ×14Biotech ×14Healthtech ×11Medical Devices ×11Cleantech ×5Deep Tech ×5IoT ×5Climate Tech ×4
HQs:United States×26South Korea×1Sweden×1
Who they back
founder profiles across 24 portfolio companiesFounding team size:solo founder×82 founders×53 founders×54+ founders×6
Where their founders studiedfrom 35 founders with education data
Massachusetts Institute of Technology ×5Columbia Business School ×2Princeton University ×2Stanford University ×2Stanford University Graduate School of Business ×2Stanford University School of Medicine ×2University of Wisconsin-Madison ×2
What their founders studiedfrom 39 founders with field-of-study data
Engineering ×13Life Sciences ×8Business & Management ×7Computer Science ×7Economics ×4Design & Architecture ×3Finance & Accounting ×3Chemistry ×2
Where their founders worked beforefrom 35 founders with career history
Google ×3Stanford University ×3Unreasonable ×3Georgia Institute of Technology ×2Harvard Medical School ×2Microsoft ×2
Accelerator rootsportfolio companies that came through a program
14 founders hold a PhD · 8 hold an MBA (of 39 with degree data)
Investments · 31 tracked
founders shown can be your intro pathBy year:2025 · 12024 · 32021 · 22020 · 12019 · 12018 · 22017 · 32016 · 12015 · 115 dated
AiFi uses AI and computer vision to make physical spaces searchable, observable, and understandable, providing real-time insights for facility and space operators without manual audits.
AI & Machine LearningEnterprise SoftwareIoTRetail Tech
Steve Gu(Founder & CEO)Ying Zheng(Founder)in
Co-investorsAmino CapitalBRC InnovationCervinCommunitas Capital PartnersDuke Capital PartnersEvolution Ventures+9 more
Air Protein produces protein made from elements in the air through a fermentation-based process, creating a land-independent food ingredient.
BiotechClimate TechFoodTechPleasanton, US
Lisa Dyson(CEO)Ori Sasson(Director)James White(Executive Officer, Director)Joseph Grundfest(Director)Maisie Ganzler(Director)John Reed(Founder)
Co-investorsGV (Google Ventures)Kapor CapitalRadicle ImpactFearless FundGingerbread Capital
ARIX combines robotics and data analytics to inspect and manage critical industrial assets.
AI & Machine LearningDeep TechEnergyIoTRoboticsJackson, US
Dianna Liu(President and CEO)in
Co-investorsAlleyCorpContour Venture PartnersCreative Destruction Lab (CDL)Dorm RoomEnergy Transition VenturesInnovation Catalyst+5 more
AVTTX is a clinical-stage company developing gene therapy treatments for retinal and ophthalmologic diseases.
BiotechDigital HealthHealthtechMedical Devices
George Montgomery(Executive Chairman)
Co-investorsEcoR1 CapitalEvolution VC PartnersHelios CapitalSand Hill AngelsTransform InvestmentsSocii Capital+1 more
Biobot pioneers wastewater epidemiology, monitoring pathogens and substances in sewage to provide real-time public health surveillance at the community level.
BiotechData & InfrastructureGovTechHealthtechBoston, US
Newsha Ghaeli(President)inMariana Matus(Founder)inMariana Guadalupe Matus Garcia(Executive Officer, Director)Ayo Omojola(Investor)in
BoardVivek Pattipati(Director)inAndrew Perlman(Director)in
Co-investorsAmerican Family Insurance Institute for Corporate and Social ImpactBlindspot Ventures Management CoDCVC (Data Collective)DesignXDorm RoomHomebrew+22 more
BioEclipse Therapeutics is a clinical-stage oncology company developing immuno-oncology therapeutics using a proprietary platform that targets the tumor microenvironment through engineered immune cell therapies.
BiotechDigital HealthHealthtechMedical DevicesSouth San Francisco, US
Pamela Reilly Contag(Executive Officer, Director)Catherine Sohn(Director)Gregory Schiffman(Director)Mark Frohlich(Director)Stephen Thau(Executive Officer)Elona Baum(Director)
Co-investorsFoothill Ventures
Cordex Systems develops SmartCuff, a medical device that repurposes blood pressure cuff technology as a linear sensor to detect early warning signs of heart disease.
AI & Machine LearningBiotechHealthtechMedical DevicesAnnapolis, US
Kathy Elizabeth Magliato(Founder, CEO, CMO)Albert Fleury IIIinMichael Whitt(Founder and Inventor)in
BoardDennis SchmulandinGeorge Abein
Co-investorsGingerbread Capital
Diligent Robotics develops AI-powered robot assistants for healthcare settings, focusing on mobile manipulation and social intelligence to help hospital staff with routine non-patient-facing tasks.
AI & Machine LearningHealthtechMedical DevicesRoboticsAustin, US
Andrea L. Thomaz(Founder)inVivian Chu(Founder)inAndrea Thomaz(Founder)
BoardQuaeed Motiwala(Director)Rohit Sharma(Director)inLance VandenBrook(Director)
Co-investorsATPCanaan PartnersCorrelation VenturesDnx VenturesGrit VenturesInterwoven Ventures+12 more
Einride develops autonomous electric vehicles and fleet management solutions for decarbonization, serving large enterprises seeking to reduce emissions at scale.
AI & Machine LearningCleantechClimate TechLogistics & Supply ChainMobility & TransportationStockholm, SE
Robert Falck(Founder)inLinnéa Kornehed Falck(Co-Founder)inFilip Lilja(Founder)inRoozbeh Charli(Chief Executive Officer)inHenrik Green(CTO)inLinnéa Kornehed(Founder)
Co-investorsMaersk GrowthNordicNinjaNordicNinjaVCNorthzoneWolfswood PartnersEQT Ventures+4 more
EpiBone engineers bone tissue from stem cells for regenerative medicine and clinical reconstruction, serving patients requiring bone grafts or craniofacial repair.
BiotechHealthtechMedical DevicesNew York, US
Nina Tandon(Co-Founder, CEO)inSarindr Bhumiratana(Co-Founder)inGordana Vunjak-Novakovic(Director)Elma Hawkins(Director)
BoardRobert Langer(Director)David Zhu(Director)in
Co-investorsBeresford VenturesCatalytic Impact FoundationEMV CapitalHackensack Meridian Health Bear's DenKendall Capital PartnersLifespan Vision Ventures+3 more
Evrnu develops technology to transform textile waste into recyclable fibers for apparel manufacturing, creating sustainable alternatives to conventional textiles without compromising quality or performance.
Circular EconomyCleantechClimate TechNew MaterialsSeattle, US
Christopher Stanev(Executive Officer, Director)inStacy Flynn(Executive Officer, Director)inChristopher Stenev(Executive Officer, Director, Promoter)
BoardCorey Vernon(Director)inKyle Adkins(Director)Julie Guggemos(Director)
Co-investorsE8 AngelsGotham Gal VenturesMagic HourRadicle ImpactFor Good VenturesGiant Leap+1 more
One Health operates a clinical trial platform using canine cancer data to accelerate and de-risk human oncology drug development.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesSan Francisco, US
Christina Lopes(Founder)inBenjamin Lewis(COO)inchristina lopesinPedro Carrasco(Chief of Staff)Christi Miller(Head of Operations)
Co-investorsAndreessen HorowitzaVentureCivilization Ventures Management, LlcGlobal BrainIKJ CapitalMaC Venture Capital+15 more
Gameto develops cell therapy and reproductive technologies to treat infertility and improve women's health outcomes.
BiotechFemTechHealthtechMedical DevicesAustin, US
Dina Turner(Co-founder & Chief Executive Officer)inMartin Varsavsky(Co-founder & Chairman)inDina Radenkovic(Founder)inMartín Varsavsky(Founder)
BoardDusan Perovic(Director)inDylan Morris(Director)in
Co-investorsBold Capital PartnersDeviation CapitalFJ LabsFuture VenturesIngeborg InvestmentsInsight Partners+18 more
Helaina uses precision fermentation to produce human proteins, including lactoferrin and other bioactive nutrients found in human milk, for consumer nutrition products serving athletes, new parents, and health-conscious consumers.
AI & Machine LearningBiotechFoodTechHealthtechNew York, US
Laura Katz(Founder)in
Co-investorsBarrel VenturesCosmic Venture PartnersIngeborg InvestmentsPrimary Venture PartnersTrousdale VenturesVisible Ventures+4 more
humans& is a frontier AI lab focused on building human-centric AI systems that prioritize people and their relationships, emphasizing innovations in reinforcement learning, memory, and user understanding to create AI that strengthens organizations and communities.
AI & Machine LearningEnterprise SoftwareSaaSEl Segundo, US
Eric Zelikman(Founder)inNoah Goodman(Founder)inGeorges Harik(Founder)Alaarif Nooruldeen(Executive Officer, Director)Andi Peng(Founder)Ray Ramadorai(Founder)
Co-investorsGV (Google Ventures)S32SV AngelNVIDIAA.Capital VenturesAlumni Ventures+19 more
InnerPlant develops living sensor technology that enables farmers to detect plant stress in real-time, allowing targeted application of treatments to reduce chemical use and increase crop yields.
AgTechAI & Machine LearningBiotechDeep TechIoTRoboticsCalifornia, US
RodinShely Aronov(Executive Officer, Director)inMichael Berolzheimer(Founder & Managing Partner)inGary Schaefer(Chief Commercial Officer)in
BoardJocelyne Cooke(CFO)in
Co-investorsBee PartnersBison VenturesCultiv8 Funds ManagementKokopelli CapitalMS&AD VenturesNimble Partners+6 more
Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.
AI & Machine LearningBiotechLongevityMedical DevicesRedwood City, US
Jeremy O'Connell, PhD(Chief Scientific Officer and Co-Founder)Hanadie Yousef, PhD(Co-Founder, Director and Executive Advisor)Jeremy O'Connell(Director)inDr. Hanadie Yousef(Founder)inJulie Anne Smith(Chief Executive Officer and Director)in
BoardBen Hemani(Director)in
Co-investorsAlumni VenturesBascom VenturesBison VenturesCompoundHarmonix FundHorizons Ventures+5 more
KETOS develops an automated water quality and monitoring platform combining hardware, connectivity, software, and services to test water safety and efficiency for cities and businesses.
AI & Machine LearningCleantechData & InfrastructureEnterprise SoftwareIoTMilpitas, US
Meena Sankaran(Executive Officer, Director)inVeery Maxwell(Director)
BoardHeidi Patel(Director)inOllen Douglass(Director)
Co-investorsRethink ImpactBetter Ventures Central LlcMotley Fool VenturesThe Perkins FundAccenture Ventures
Kraus Hamdani Aerospace develops ultra-long-endurance autonomous aircraft and AI-enabled airborne systems that provide persistent connectivity, intelligence, and communications infrastructure for defense and national security missions.
AI & Machine LearningDefense TechHardwareIoTRoboticsReno, US
Fatema Hamdani(Co-Founder, CEO)inStefan Kraus(Co-Founder, CTO)in
Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.
BiotechDeep TechMedical DevicesBrisbane, US
Jennifer Doudna(Founder)inTrevor Martin(Founder)inJanice Chen(Founder)inLucas Harrington(Founder)inAshley Tehranchi(Founder)in
BoardUrshit Parikh(Director)
Co-investors8VCBerkeley FrontierCalifornia Innovation FundDecheng CapitalForesite CapitalMayfield Fund+12 more
Markable.ai is an all-in-one platform for affiliate creators to monetize content through Amazon, Target, and Walmart deeplinks, featuring automated tools for link management, content boosting, and performance optimization.
AI & Machine LearningCreator EconomyMarketing TechMadison, US
Joy Tang(Executive Officer, Director)inFiona Wang(Executive Officer, Director)
BoardSheng Fu(Director)
Co-investorsArbor VenturesFounderPartnersFoundersX VenturesNOEMIS VenturesPartech VenturesHeadline
Openwater develops an imaging platform using two optical modalities designed to diagnose and monitor diseases at the size and cost of a smartphone.
AI & Machine LearningDeep TechHardwareHealthtechMedical DevicesSan Francisco, US
Dr. Mary Lou Jepsen(Executive Chairman & Founder)in
Co-investorsAIR CapitalBold Capital PartnersCleveland AvenueCollaborative FundColterExcel Venture Management+6 more
OpenWater is a membership-based network for accomplished professionals who want to continue doing meaningful work while maintaining access to peer expertise, mentorship, and professional opportunities.
Future of WorkSaaSSector AgnosticSocialSan Francisco, US
Co-investorsResolute VenturesLauder Partners
Phoenix Tailings develops clean technology for rare earth element refining in the United States.
Advanced ManufacturingCleantechClimate TechEnergyFintechNew MaterialsBoston, US
Thomas Villalón(Chief Technology Officer & Co-Founder)Anthony Balladon(Founder)inMichelle Chao(Founder)inNick Myers(Chief Executive Officer & Co-Founder)inNicholas Myers(Founder)Tomas Villalon(Founder)
Co-investorsBantam GroupBMW i VenturesCoalitionGeodesic CapitalIn-Q-TelMPower+13 more
Siren Biotechnology develops next-generation AAV (adeno-associated virus) platforms for gene therapy applications, including gene repair, gene transfer, and gene editing.
BiotechDigital HealthMedical DevicesSan Francisco, US
Dr. Nicole Paulk(CEO, Founder, and President)inLauren Kelly(Founder)inSharon Tetlow(Director)Brad Allen(Director)
Co-investorsArtis VenturesAvilaCarnrite VenturesCivilization Ventures Management, LlcHAWKTAILNZVC+3 more
ThinkCERCA develops K-12 writing software and curriculum designed to teach critical thinking skills to students through structured literacy instruction.
EdTechChicago, US
Eileen Murphy(Executive Officer, Director)inAbby Ross(Executive Officer)inJoshua Tolman(Executive Officer)
BoardChuck Templeton(Director)
Co-investorsEdovate CapitalG2T3V FundGreat Oaks Venture CapitalHis FundNovel CapitalUnreasonable+3 more
A Korean company operating in cryogenics, materials, and high-voltage fields.
Deep TechHardwareNew MaterialsAnyang, KR
Co-investorsKiwoom InvestmentSpinLabTAL Education Group
Northampton, US
Brian Fitzgerald(Executive Officer, Director)inMeghan Fitzgerald(Director)
BoardIsabelle Hau(Director)
Co-investorsBlue CollectiveCity LightOutbound VenturesOwl VenturesVista Venture Partners500 Global+5 more
Vyv develops UV-free, chemical-free antimicrobial lighting technology using visible spectrum LEDs that continuously reduce microbial growth in occupied indoor spaces.
CleantechHardwareHealthtech
Colleen Costello(CEO)in
Co-investorsAlerion VenturesTamiami AngelTech Square VenturesWellstarCiti Ventures
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AclimaAshvattha Therapeutics
Portfolio news
latest coverage across their companiesGameto · insightpartners.com · Mar 4, 2026
Einride · techcrunch.com · Feb 26, 2026
Phoenix Tailings · finsmes.com · Feb 20, 2026
humans& · techcrunch.com · Jan 20, 2026
Juvena Therapeutics · finsmes.com · Jan 13, 2026
Frequently asked questions
- How many investments has Plum Alley Investments made?
- Plum Alley Investments has 31 tracked investments, 1 of which have exited, including 1 dated in the last 24 months.
- What stage does Plum Alley Investments invest at?
- Plum Alley Investments invests at the Seed, Series A stages.
- What is Plum Alley Investments's typical check size?
- Plum Alley Investments typically writes checks of $500K – $1.5M.
- What sectors does Plum Alley Investments focus on?
- Plum Alley Investments focuses on AI & Machine Learning, Biotech, Deep Tech, Enterprise Software, Hardware, Impact & Social Good, Medical Devices.
- Where is Plum Alley Investments located?
- Plum Alley Investments is headquartered in New York, US.
- Does Plum Alley Investments lead rounds?
- Plum Alley Investments typically participates in rounds rather than leading them.
- Who does Plum Alley Investments co-invest with?
- Plum Alley Investments most often shares deals with StartX, Collaborative Fund, DCVC (Data Collective), among 191 tracked co-investors.
Co-investors · 20
Rethink Impact is a venture capital firm that backs leaders using technology to address major global challenges, focused on mission-driven companies aiming to benefit all communities.
Tachyon Ventures provides early-stage capital to entrepreneurs building companies in medicine, biotech and bioengineering, supported by a network of scientists at leading research institutions.
Khosla Ventures is a venture capital firm that backs bold, early-stage, technology-driven companies across deep tech and other sectors, providing hands-on 'venture assistance' to help founders build category-defining businesses.
Spark Capital is a venture capital firm that partners with founders, known for early investments including leading Twitter's Series B in 2008.
Great Oaks Venture Capital is a New York-based seed and early-stage investor that backs founders building enduring businesses across the United States.
Mayfield is a venture capital firm that invests in early-stage consumer and marketplace companies, backing founders from inception through IPO.
EQT Ventures is the venture capital arm within the EQT platform, backing early-stage European founders building what it calls Generation-Defining Companies.
Northzone is a technology-focused venture capital firm investing across AI and deep tech on both sides of the Atlantic, backing companies from early stage through growth.
Robert Bosch Venture Capital GmbH (Bosch Ventures) is the corporate venture capital arm of Robert Bosch, headquartered in Stuttgart, Germany, with offices across Europe, the US, Israel, and China.
Hustle Fund is an early-stage venture capital firm that invests quickly in startups, offering capital along with educational programs and mentorship. It also runs an angel investing community that lets members invest alongside the fund.
Pareto Holdings is an early-stage investment and company-building firm headquartered in the United States that operates globally. It has never raised outside capital and is self-funded by design.
▶8 more co-investors
AntlerNext Play VenturesNorrsken VCTriatomic CapitalClearvision VenturesConteur Capital PartnersS2G InvestmentsTectonic Capital
Firms observed investing alongside Plum Alley Investments, from public investor directories. Shared companies are the overlap with Plum Alley Investments's recorded portfolio.
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